pyrazines has been researched along with glutamic acid in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.26) | 18.2507 |
| 2000's | 4 (21.05) | 29.6817 |
| 2010's | 11 (57.89) | 24.3611 |
| 2020's | 3 (15.79) | 2.80 |
| Authors | Studies |
|---|---|
| Campbell, AK; Watkins, NJ | 1 |
| Alavijeh, M; Böhme, GA; Boireau, A; Bordier, F; Brealey, C; Briet, D; Canton, T; Debono, MW; Jahn, G; Jimonet, P; Laville, M; Le Guern, S; Mignani, S; Pratt, J; Roberts, S; Roux, M; Stutzmann, JM; Stygall, J; Vuilhorgne, M | 1 |
| Hurley, LM | 1 |
| Dodd, PG; Gayton, S; Greener, BS; Harbottle, GW; Mantell, SJ; Maw, GN; Osborne, SA; Owen, DR; Rees, H; Ringer, TJ; Rodriguez-Lens, M; Smith, GF | 1 |
| Cheng, FC; Cheng, H; Chou, SC; Fu, YS; Fu, YY; Hsu, SY; Kao, LS; Lin, YY; Shih, YH; Tsai, TH; Wang, JY | 1 |
| Appleyard, SM; Cui, RJ; Roberts, BL; Zhao, H; Zhu, M | 1 |
| Chang, CH; Chen, SH; Huang, WT; Kao, CH; Lin, CH | 1 |
| Bianchi, E; Cerretani, D; Ghelardini, C; Menicacci, C | 1 |
| Bie, XD; Ge, LJ; Han, J; Wan, HT; Yang, JH; Zhang, YY | 1 |
| Teng, F; Tu, J; Zhang, C; Zhang, D | 1 |
| Anderson, DR; Buisson, B; Fagiolini, M; Fanger, CM; Gleyzes, M; Gordon, E; Menniti, FS; Mierau, SB; Paschetto, K; Sirivolu, VR; Steidl, E; Virginio, C; Volkmann, RA | 1 |
| Chen, H; Han, Y; Hu, S; Hu, Y; Mak, S; Sun, Y; Tsim, KWK; Wang, Y; Xu, D; Zhang, G; Zhang, Z | 1 |
| Yang, YN; Yu, AN; Zhou, YY | 1 |
| Fujita, T; Kumamoto, E; Piao, LH; Yu, T | 1 |
| Cameron, CE; Ciota, AT; Gohara, DW; Griesemer, SB; Kramer, LD; Pata, JD; Van Slyke, GA | 1 |
| Gu, J; Li, C; Liu, W; Long, C; Shan, L; Sun, Y; Wang, Y; Wu, L; Xu, L; Yang, X; Zhang, G; Zhang, T; Zhang, Z; Zhou, X | 1 |
| Lu, T; Tong, H; Wang, K; Wang, X | 1 |
| Cui, H; Hayat, K; Ho, CT; Xia, X; Zhai, Y; Zhang, H; Zhang, X | 1 |
| Cui, H; Hayat, K; Ho, CT; Xia, X; Zhang, F; Zhang, H; Zhang, X; Zhou, T | 1 |
19 other study(ies) available for pyrazines and glutamic acid
| Article | Year |
|---|---|
Requirement of the C-terminal proline residue for stability of the Ca(2+)-activated photoprotein aequorin.
Topics: Aequorin; Animals; Base Sequence; Calcium; DNA; Electrophoresis, Agar Gel; Glutamates; Glutamic Acid; Histidine; Imidazoles; In Vitro Techniques; Luminescent Measurements; Molecular Sequence Data; Mutation; Polymerase Chain Reaction; Proline; Protein Biosynthesis; Pyrazines; Recombinant Proteins; Scyphozoa | 1993 |
RPR 119990, a novel alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid antagonist: synthesis, pharmacological properties, and activity in an animal model of amyotrophic lateral sclerosis.
Topics: Amyotrophic Lateral Sclerosis; Animals; Anticonvulsants; Disease Progression; Electrophysiology; Electroshock; Excitatory Amino Acid Antagonists; Glutamic Acid; Imidazoles; In Vitro Techniques; Longevity; Mice; Mice, Transgenic; Muscle, Skeletal; Neurons; Patch-Clamp Techniques; Pyrazines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Superoxide Dismutase | 2001 |
Different serotonin receptor agonists have distinct effects on sound-evoked responses in inferior colliculus.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acoustic Stimulation; Animals; Chiroptera; Dose-Response Relationship, Drug; Electrodes; Electrophysiology; Evoked Potentials, Auditory; Extracellular Space; gamma-Aminobutyric Acid; Glutamic Acid; Inferior Colliculi; Iontophoresis; Male; Pyrazines; Pyridines; Pyrroles; Receptor, Serotonin, 5-HT1A; Serotonin; Serotonin Receptor Agonists | 2006 |
Structure-activity relationships of novel non-competitive mGluR1 antagonists: a potential treatment for chronic pain.
Topics: Animals; Binding, Competitive; Chemical Phenomena; Chemistry, Physical; CHO Cells; Chronic Disease; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Glutamic Acid; Pain; Pyrazines; Rats; Receptors, Metabotropic Glutamate; Structure-Activity Relationship | 2007 |
Tetramethylpyrazine inhibits activities of glioma cells and glutamate neuro-excitotoxicity: potential therapeutic application for treatment of gliomas.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Coculture Techniques; Glioma; Glutamic Acid; Microdialysis; Nerve Degeneration; Neurons; Pyrazines; Rats; Rats, Sprague-Dawley; Xenograft Model Antitumor Assays | 2008 |
Serotonin activates catecholamine neurons in the solitary tract nucleus by increasing spontaneous glutamate inputs.
Topics: Action Potentials; Animals; Catecholamines; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Male; Mice; Neurons; Patch-Clamp Techniques; Piperazines; Pyrazines; Quinoxalines; Receptors, Presynaptic; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin Receptor Agonists; Solitary Nucleus; Tyrosine 3-Monooxygenase | 2012 |
Tetramethylpyrazine decreases hypothalamic glutamate, hydroxyl radicals and prostaglandin-E2 and has antipyretic effects.
Topics: Animals; Antipyretics; Body Temperature; Dinoprostone; Glutamic Acid; Hydroxyl Radical; Hypothalamus; Lipopolysaccharides; Male; Pyrazines; Rabbits; Tumor Necrosis Factor-alpha | 2013 |
Spinal administration of mGluR5 antagonist prevents the onset of bortezomib induced neuropathic pain in rat.
Topics: Analgesics; Animals; Boronic Acids; Bortezomib; Ceftriaxone; Cell Line, Tumor; Cell Survival; Central Nervous System Agents; Disease Models, Animal; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Hyperalgesia; Injections, Spinal; Male; Neural Conduction; Neuralgia; Peripheral Nervous System Diseases; Pyrazines; Pyridines; Random Allocation; Rats; Receptor, Metabotropic Glutamate 5 | 2014 |
Effect of ligustrazine on levels of amino acid neurotransmitters in rat striatum after cerebral ischemia-reperfusion injury.
Topics: Amino Acids; Animals; Aspartic Acid; Brain; Brain Ischemia; Corpus Striatum; gamma-Aminobutyric Acid; Glutamic Acid; Infarction, Middle Cerebral Artery; Male; Microdialysis; Molecular Structure; Neurotransmitter Agents; Pyrazines; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Taurine; Time Factors | 2014 |
Ultrasound-enhanced protective effect of tetramethylpyrazine against cerebral ischemia/reperfusion injury.
Topics: Animals; bcl-2-Associated X Protein; Brain Ischemia; Glutamic Acid; High-Energy Shock Waves; Interleukin-8; Ligusticum; Medicine, Chinese Traditional; Microscopy, Electron, Scanning; PC12 Cells; Proto-Oncogene Proteins c-bcl-2; Pyrazines; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Superoxide Dismutase; Tumor Necrosis Factor-alpha; Vasodilator Agents | 2014 |
MPX-004 and MPX-007: New Pharmacological Tools to Study the Physiology of NMDA Receptors Containing the GluN2A Subunit.
Topics: Animals; CA1 Region, Hippocampal; Calcium; Cells, Cultured; Dogs; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Glycine; Humans; Ion Channel Gating; Madin Darby Canine Kidney Cells; Male; Neurons; Oocytes; Protein Subunits; Pyrazines; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship; Sulfonamides; Xenopus | 2016 |
Neuroprotection against glutamate-induced excitotoxicity and induction of neurite outgrowth by T-006, a novel multifunctional derivative of tetramethylpyrazine in neuronal cell models.
Topics: Animals; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Glutamic Acid; Hydrazones; Neuronal Outgrowth; Neurons; Neuroprotection; PC12 Cells; Pyrazines; Rats; Rats, Sprague-Dawley | 2016 |
Kinetics of browning and correlations between browning degree and pyrazine compounds in l-ascorbic acid/acidic amino acid model systems.
Topics: Amino Acids; Ascorbic Acid; Aspartic Acid; Glutamic Acid; Kinetics; Maillard Reaction; Models, Biological; Pyrazines | 2017 |
Presynaptic facilitation by tetracaine of glutamatergic spontaneous excitatory transmission in the rat spinal substantia gelatinosa - Involvement of TRPA1 channels.
Topics: Acetanilides; Amides; Anesthetics, Local; Animals; Bupivacaine; Capsaicin; Excitatory Postsynaptic Potentials; Glutamic Acid; Levobupivacaine; Male; Neurotransmitter Agents; Pain; Patch-Clamp Techniques; Presynaptic Terminals; Prilocaine; Purines; Pyrazines; Pyridines; Rats, Sprague-Dawley; Ropivacaine; Ruthenium Red; Substantia Gelatinosa; Tetracaine; Tetrodotoxin; Tissue Culture Techniques; TRPA1 Cation Channel; TRPC Cation Channels | 2017 |
Mutagen resistance and mutation restriction of St. Louis encephalitis virus.
Topics: Amino Acid Substitution; Antiviral Agents; Drug Resistance, Viral; Encephalitis Virus, St. Louis; Encephalitis, St. Louis; Glutamic Acid; HeLa Cells; Humans; Lysine; Models, Molecular; Mutagens; Mutation; Nucleosides; Protein Domains; Pyrazines; Ribavirin; RNA-Dependent RNA Polymerase; Viral Nonstructural Proteins | 2017 |
Neuroprotective Effect and Mechanism of Action of Tetramethylpyrazine Nitrone for Ischemic Stroke Therapy.
Topics: Animals; Apoptosis Regulatory Proteins; Calcium; Cell Hypoxia; Cells, Cultured; Drug Evaluation, Preclinical; Free Radical Scavengers; Glucose; Glutamic Acid; Infarction, Middle Cerebral Artery; Lipid Peroxidation; Mitochondria; Motor Activity; Nerve Tissue Proteins; Neuroprotective Agents; Nitrogen Oxides; Patch-Clamp Techniques; Protein Kinase Inhibitors; Pyrazines; Rats; Rats, Sprague-Dawley; Signal Transduction | 2018 |
Molecular Mechanism of Tetramethylpyrazine Ameliorating Neuroexcitotoxicity through Activating the PKA/CREB Signaling Pathway.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Cyclic AMP-Dependent Protein Kinases; Glutamic Acid; Molecular Docking Simulation; Neurons; PC12 Cells; Proto-Oncogene Proteins c-bcl-2; Pyrazines; Rats; Signal Transduction | 2022 |
Structural diversity and concentration dependence of pyrazine formation: Exogenous amino substrates and reaction parameters during thermal processing of l-alanyl-l-glutamine Amadori compound.
Topics: Chromatography, Liquid; Dipeptides; Glutamic Acid; Glutamine; Maillard Reaction; Pyrazines; Tandem Mass Spectrometry | 2022 |
Simultaneously Enhanced Formation of Pyrazines and Furans during Thermal Degradation of the Glycyl-l-glutamine Amadori Compound by Selected Exogenous Amino Acids and Appropriate Elevated Temperatures.
Topics: Amino Acids; Chromatography, Liquid; Furans; Glutamic Acid; Maillard Reaction; Pyrazines; Tandem Mass Spectrometry; Temperature | 2023 |