Page last updated: 2024-08-21

pyrazines and fluorine

pyrazines has been researched along with fluorine in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19902 (25.00)18.7374
1990's0 (0.00)18.2507
2000's3 (37.50)29.6817
2010's3 (37.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baer, JE; Bohn, DL; Fanelli, GM; Reilly, SS1
Kar, PP; Martin, MA1
Fujiwara, I; Kurono, M; Yoshida, K1
Ayrtont, J; Bowers, GD; Dear, GJ; Ismail, IM; Plumb, RS; Roberts, AD; Sweatman, BC1
Alkorta, I; Del Bene, JE; Elguero, J1
Basso, AD; Doll, RJ; Esposite, SJ; Gray, K; Jones, J; Kerekes, AD; Lee, S; Liu, M; Prelusky, DB; Smith, EB; Tagat, JR; Terracina, GA; Tevar, S; Xiao, Y; Yu, T; Zhang, Y1
Béni, S; Hu, WH; Li, H; Noszál, B; Sohajda, T; Szente, L; Zeng, LL1
Ding, Y; Dong, L; Jiang, MH; Shah, V; Shen, WB; Sun, LL; Zhang, FF; Zheng, F1

Other Studies

8 other study(ies) available for pyrazines and fluorine

ArticleYear
Renal excretion and uricosuric properties of halofenate, a hypolipidemic-uricosuric agent, in the chimpanzee.
    The Journal of pharmacology and experimental therapeutics, 1972, Volume: 180, Issue:2

    Topics: Acetamides; Aminohippuric Acids; Animals; Carbon Isotopes; Carboxylic Acids; Clofibrate; Diuresis; Fluorine; Glycolates; Hydrogen-Ion Concentration; Hypolipidemic Agents; Kidney; Kidney Function Tests; Kidney Tubules; Kinetics; Male; Pan troglodytes; Probenecid; Pyrazines; Salicylates; Uricosuric Agents

1972
Effect of cholinesterase inhibitors and PAM on the release of acetylcholine from isolated guinea pig ileum.
    Japanese journal of pharmacology, 1971, Volume: 21, Issue:5

    Topics: Acetylcholine; Amines; Aminosalicylic Acids; Animals; Cholinesterase Inhibitors; Fluorine; Guinea Pigs; Ileum; In Vitro Techniques; Muscle, Smooth; Neostigmine; Organophosphorus Compounds; Phosphamidon; Physostigmine; Propylamines; Pyrazines; Stimulation, Chemical

1971
Stereospecific interaction of a novel spirosuccinimide type aldose reductase inhibitor, AS-3201, with aldose reductase.
    Biochemistry, 2001, Jul-27, Volume: 40, Issue:28

    Topics: Aldehyde Reductase; Binding Sites; Bromosuccinimide; Enzyme Inhibitors; Enzyme Stability; Fluorine; Holoenzymes; Humans; Hydrogen-Ion Concentration; Kinetics; Ligands; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Pyrazines; Spectrometry, Fluorescence; Spiro Compounds; Stereoisomerism; Substrate Specificity; Succinimides; Temperature; Titrimetry

2001
N-O glucuronidation: a major human metabolic pathway in the elimination of two novel anti-convulsant drug candidates.
    Xenobiotica; the fate of foreign compounds in biological systems, 2002, Volume: 32, Issue:1

    Topics: Animals; Anticonvulsants; Dogs; Female; Fluorine; Fluorobenzenes; Glucuronides; Humans; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Molecular Structure; Pyrazines; Rats; Rats, Sprague-Dawley

2002
Characterizing complexes with F-Li...N, H-Li...N, and CH3Li...N lithium bonds: structures, binding energies, and spin-spin coupling constants.
    The journal of physical chemistry. A, 2009, Sep-24, Volume: 113, Issue:38

    Topics: Ammonia; Fluorine; Hydrochloric Acid; Hydrogen; Lithium; Methylamines; Molecular Structure; Nitrogen; Pyrazines; Pyridines; Quantum Theory; Triazines

2009
Aurora kinase inhibitors based on the imidazo[1,2-a]pyrazine core: fluorine and deuterium incorporation improve oral absorption and exposure.
    Journal of medicinal chemistry, 2011, Jan-13, Volume: 54, Issue:1

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Aurora Kinases; Biological Availability; Cell Line, Tumor; Deuterium; Dogs; Drug Screening Assays, Antitumor; Fluorine; Histones; Humans; Imidazoles; Macaca fascicularis; Mice; Mice, Nude; Neoplasm Transplantation; Phosphorylation; Protein Serine-Threonine Kinases; Pyrazines; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Transplantation, Heterologous

2011
Evaluation of the interaction between sitagliptin and cyclodextrin derivatives by capillary electrophoresis and nuclear magnetic resonance spectroscopy.
    Electrophoresis, 2011, Volume: 32, Issue:19

    Topics: Cyclodextrins; Electrophoresis, Capillary; Fluorine; Hydrogen-Ion Concentration; Nuclear Magnetic Resonance, Biomolecular; Pyrazines; Sitagliptin Phosphate; Stereoisomerism; Temperature; Triazoles

2011
Quantitative analysis of sitagliptin using the (19)F-NMR method: a universal technique for fluorinated compound detection.
    The Analyst, 2015, Jan-07, Volume: 140, Issue:1

    Topics: Fluorine; Magnetic Resonance Spectroscopy; Pyrazines; Sitagliptin Phosphate; Triazoles

2015