Compounds > pyrazines
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pyrazines and fenretinide

pyrazines has been researched along with fenretinide in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (45.45)29.6817
2010's6 (54.55)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Aggarwal, BB; Gutierrez, AM; Lotan, R; Shishodia, S1
Bhat, GJ; Niture, SK; Smith, QR; Srivenugopal, KS; Velu, CS1
Armstrong, JL; Birch-Machin, MA; Brown, AM; Corazzari, M; Hill, D; Lovat, PE; Martin, S; Pagliarini, V; Piacentini, M; Redfern, CP1
Armstrong, JL; Birch-Machin, MA; Flockhart, R; Hill, DS; Lovat, PE; Martin, S; Redfern, CP; Simpson, DG; Tonison, JJ1
Brignole, C; Carosio, R; Cilli, M; Di Paolo, D; Galietta, LJ; Loi, M; Marimpietri, D; Nico, B; Pagnan, G; Pastorino, F; Pezzolo, A; Piccardi, F; Pistoia, V; Ponzoni, M; Ribatti, D1
Armstrong, JL; Flockhart, R; Lovat, PE; Redfern, CP; Veal, GJ1
Armstrong, JL; Birch-Machin, M; Fulda, S; Harbottle, A; Hill, DS; Hiscutt, EL; Kerr, R; Lovat, PE; Martin, S; Redfern, CP1
Birch-Machin, MA; Hill, DS; Lovat, PE; Martin, S; Paton, AW; Paton, JC; Redfern, CP1
Al Sabah, S; Armstrong, JL; Corazzari, M; Ellis, N; Falasca, L; Fimia, GM; Hill, DS; Lovat, PE; Martin, S; Pagliarini, V; Piacentini, M; Redfern, CP1
Lovat, PE; Martin, S; Redfern, CP1
Cowan, AJ; Frayo, SL; Gopal, AK; Green, DJ; Pagel, JM; Palanca-Wessels, MC; Press, OW1

Other Studies

11 other study(ies) available for pyrazines and fenretinide

ArticleYear
N-(4-hydroxyphenyl)retinamide inhibits invasion, suppresses osteoclastogenesis, and potentiates apoptosis through down-regulation of I(kappa)B(alpha) kinase and nuclear factor-kappaB-regulated gene products.
    Cancer research, 2005, Oct-15, Volume: 65, Issue:20

    Topics: Antineoplastic Agents; Apoptosis; Boronic Acids; Bortezomib; Carcinoma, Small Cell; Carrier Proteins; Cell Growth Processes; Cyclin D1; Cyclooxygenase 2; Down-Regulation; Drug Synergism; Enzyme Activation; Fenretinide; Genes, myc; Humans; I-kappa B Kinase; I-kappa B Proteins; Lung Neoplasms; Membrane Glycoproteins; NF-kappa B; NF-KappaB Inhibitor alpha; Oncogene Protein v-akt; Osteoclasts; Phosphorylation; Promoter Regions, Genetic; Proto-Oncogene Proteins c-myc; Pyrazines; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; Transcription Factor RelA; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A

2005
Increased expression of the MGMT repair protein mediated by cysteine prodrugs and chemopreventative natural products in human lymphocytes and tumor cell lines.
    Carcinogenesis, 2007, Volume: 28, Issue:2

    Topics: Acetylcysteine; Anticarcinogenic Agents; Antioxidants; Base Sequence; Biological Products; Blotting, Western; Cell Line, Tumor; Curcumin; Cysteine; DNA Modification Methylases; DNA Primers; DNA Repair Enzymes; Dose-Response Relationship, Drug; Fenretinide; Glutathione; Glutathione S-Transferase pi; Humans; Lymphocytes; Prodrugs; Pyrazines; RNA, Messenger; Silymarin; Thiones; Thiophenes; Tumor Suppressor Protein p14ARF; Tumor Suppressor Proteins

2007
Increasing melanoma cell death using inhibitors of protein disulfide isomerases to abrogate survival responses to endoplasmic reticulum stress.
    Cancer research, 2008, Jul-01, Volume: 68, Issue:13

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bacitracin; Boronic Acids; Bortezomib; Cell Death; Cell Survival; Drug Evaluation, Preclinical; Drug Synergism; Endoplasmic Reticulum; Enzyme Inhibitors; Fenretinide; Humans; Melanoma; Oxidative Stress; Protein Disulfide-Isomerases; Pyrazines; Treatment Outcome; Tumor Cells, Cultured

2008
Combining the endoplasmic reticulum stress-inducing agents bortezomib and fenretinide as a novel therapeutic strategy for metastatic melanoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, Feb-15, Volume: 15, Issue:4

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Boronic Acids; Bortezomib; Cell Division; Cell Line, Tumor; Cell Survival; Drug Synergism; Endoplasmic Reticulum; Female; Fenretinide; G2 Phase; Humans; Ki-67 Antigen; Melanoma; Mice; Pyrazines

2009
The combined therapeutic effects of bortezomib and fenretinide on neuroblastoma cells involve endoplasmic reticulum stress response.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, Feb-15, Volume: 15, Issue:4

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Boronic Acids; Bortezomib; Cell Line, Tumor; Cell Proliferation; Chick Embryo; Endoplasmic Reticulum; Fenretinide; Humans; Mice; Neuroblastoma; Pyrazines; Xenograft Model Antitumor Assays

2009
Regulation of endoplasmic reticulum stress-induced cell death by ATF4 in neuroectodermal tumor cells.
    The Journal of biological chemistry, 2010, Feb-26, Volume: 285, Issue:9

    Topics: Activating Transcription Factor 4; Antineoplastic Agents; Boronic Acids; Bortezomib; Cell Death; Cell Line, Tumor; Endoplasmic Reticulum; Fenretinide; Humans; Neuroectodermal Tumors; Pyrazines; Signal Transduction; Stress, Physiological

2010
Targeting X-linked inhibitor of apoptosis protein to increase the efficacy of endoplasmic reticulum stress-induced apoptosis for melanoma therapy.
    The Journal of investigative dermatology, 2010, Volume: 130, Issue:9

    Topics: Antineoplastic Agents; Apoptosis; Boronic Acids; Bortezomib; Drug Resistance, Neoplasm; Endoplasmic Reticulum; Female; Fenretinide; Gene Expression Regulation, Neoplastic; Genes, ras; Humans; In Vitro Techniques; Male; Melanoma; Middle Aged; Mutation; Nevus, Pigmented; Proto-Oncogene Proteins B-raf; Pyrazines; RNA, Small Interfering; Skin Neoplasms; Stress, Physiological; X-Linked Inhibitor of Apoptosis Protein

2010
Targeting GRP78 to enhance melanoma cell death.
    Pigment cell & melanoma research, 2010, Volume: 23, Issue:5

    Topics: Antineoplastic Agents; Boronic Acids; Bortezomib; Cell Death; Cell Line, Tumor; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Fenretinide; Heat-Shock Proteins; Humans; Melanoma; Pyrazines; RNA, Small Interfering; Unfolded Protein Response

2010
Oncogenic B-RAF signaling in melanoma impairs the therapeutic advantage of autophagy inhibition.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2011, Apr-15, Volume: 17, Issue:8

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Biphenyl Compounds; Blotting, Western; Boronic Acids; Bortezomib; Cell Line, Tumor; Endoplasmic Reticulum; Female; Fenretinide; Humans; Luminescent Proteins; Melanoma; Mice; Microscopy, Fluorescence; Microtubule-Associated Proteins; Nitrophenols; Piperazines; Proto-Oncogene Proteins B-raf; Pyrazines; RNA Interference; Signal Transduction; Sulfonamides; Xenograft Model Antitumor Assays

2011
Cell-type variation in stress responses as a consequence of manipulating GRP78 expression in neuroectodermal cells.
    Journal of cellular biochemistry, 2015, Volume: 116, Issue:3

    Topics: Biomarkers; Boronic Acids; Bortezomib; Cell Death; Cell Line, Tumor; Cell Shape; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Fenretinide; Gene Knockdown Techniques; Heat-Shock Proteins; Humans; Neural Plate; Pyrazines; RNA, Small Interfering; Stress, Physiological; Unfolded Protein Response

2015
Bortezomib and fenretinide induce synergistic cytotoxicity in mantle cell lymphoma through apoptosis, cell-cycle dysregulation, and IκBα kinase downregulation.
    Anti-cancer drugs, 2015, Volume: 26, Issue:9

    Topics: Antineoplastic Agents; Apoptosis; Boronic Acids; Bortezomib; Cell Line, Tumor; Cyclin B; Cyclin D1; Cyclin D3; Drug Synergism; Fenretinide; G2 Phase Cell Cycle Checkpoints; Humans; I-kappa B Proteins; Lymphoma, Mantle-Cell; NF-KappaB Inhibitor alpha; Pyrazines

2015