pyrazines has been researched along with epidermal growth factor in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (46.15) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (38.46) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Czech, MP; Davis, RJ | 1 |
| Benos, DJ; Sapirstein, VS | 1 |
| Cassel, D; Cragoe, EJ; Glaser, L; Shaikewitz, T; Zhuang, Y | 1 |
| Besterman, JM; Cragoe, EJ; Cuatrecasas, P; Tyrey, SJ | 1 |
| Cassel, D; Glaser, L; Rothenberg, P; Schlesinger, P | 1 |
| Villereal, ML | 1 |
| Hwang, JJ; Ip, MM; Lee, PP; Mead, L | 1 |
| Bursi, R; Hiramatsu, Y; Kondo, H; Sawa, M | 1 |
| Hirayama, R; Inoue, Y; Ishibushi, E; Ito, Y; Kiyoi, T; Kondo, H; Kumihara, H; Miyasaka, T; Nakajima, F; Ohmoto, H; Sawa, M; Yamamoto, M; Yamamoto, T; Yoshiizumi, K; Yoshino, K | 1 |
| Hu, WX; Shi, YW; Tang, LJ | 1 |
| Kesarwala, AH; Piwnica-Worms, D; Samrakandi, MM | 1 |
| Dudem, S; Jain, N; Kalivendi, SV; Vangala, JR | 1 |
| Arafiles, JVV; Futaki, S; Hara, Y; Hirose, H; Imanishi, M; Kuriyama, M; Maekawa, M; Masuda, T; Shudou, M | 1 |
13 other study(ies) available for pyrazines and epidermal growth factor
| Article | Year |
|---|---|
Amiloride directly inhibits growth factor receptor tyrosine kinase activity.
Topics: Adenosine Triphosphate; Amiloride; Animals; Binding, Competitive; Carcinoma, Squamous Cell; Cell Line; Cell Membrane; Epidermal Growth Factor; ErbB Receptors; Histones; Humans; Kinetics; Mice; Phosphorylation; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrazines; Receptor, Insulin; Receptors, Cell Surface; Receptors, Platelet-Derived Growth Factor; Sodium | 1985 |
Activation of amiloride-sensitive sodium transport in C6 glioma cells.
Topics: Amiloride; Animals; Biological Transport, Active; Bradykinin; Bucladesine; Cell Line; Colchicine; Diglycerides; Epidermal Growth Factor; Glioma; Protons; Pyrazines; Rats; Sodium; Tetradecanoylphorbol Acetate | 1984 |
Characterization of potent Na+/H+ exchange inhibitors from the amiloride series in A431 cells.
Topics: Amiloride; Animals; Carrier Proteins; Cell Line; Dogs; Epidermal Growth Factor; Hydrogen-Ion Concentration; Intracellular Fluid; Kinetics; Leucine; Ouabain; Potassium; Pyrazines; Rabbits; Rubidium; Sodium-Hydrogen Exchangers; Sodium-Potassium-Exchanging ATPase | 1984 |
Inhibition of epidermal growth factor-induced mitogenesis by amiloride and an analog: evidence against a requirement for Na+/H+ exchange.
Topics: Amiloride; Animals; Carrier Proteins; Cell Line; Epidermal Growth Factor; Humans; Kinetics; Mice; Mice, Inbred BALB C; Mitosis; Protein Biosynthesis; Protons; Pyrazines; RNA; Sodium; Sodium-Hydrogen Exchangers | 1984 |
Epidermal growth factor stimulates amiloride-sensitive 22Na+ uptake in A431 cells. Evidence for Na+/H+ exchange.
Topics: Amiloride; Calcium; Carcinoma, Squamous Cell; Carrier Proteins; Cell Line; Dose-Response Relationship, Drug; Epidermal Growth Factor; Humans; Ouabain; Pyrazines; Sodium; Sodium-Hydrogen Exchangers | 1983 |
Sodium fluxes in human fibroblasts: effect of serum, Ca+2, and amiloride.
Topics: Amiloride; Blood; Calcium; Cells, Cultured; Epidermal Growth Factor; Fibroblasts; Humans; Male; Penis; Pyrazines; Sodium | 1981 |
Functional role of matrix metalloproteinases (MMPs) in mammary epithelial cell development.
Topics: Animals; Cell Size; Cells, Cultured; Culture Media, Conditioned; Culture Media, Serum-Free; Epidermal Growth Factor; Epithelial Cells; Extracellular Matrix; Female; Gelatinases; Humans; Hydroxamic Acids; Immunoblotting; Mammary Glands, Animal; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Mice; Organoids; Peptides; Phenylalanine; Phenylmercury Compounds; Protease Inhibitors; Pyrazines; Rats; Rats, Sprague-Dawley; Sulfonamides; Thiophenes; Transforming Growth Factor alpha | 2001 |
A three-dimensional quantitative structure-activity relationship study of heparin-binding epidermal growth factor shedding inhibitors using comparative molecular field analysis.
Topics: Epidermal Growth Factor; Heparin-binding EGF-like Growth Factor; Humans; Intercellular Signaling Peptides and Proteins; Isoquinolines; Ligands; Models, Molecular; Molecular Conformation; Protein Binding; Pyrazines; Quantitative Structure-Activity Relationship; Sulfonamides; Tumor Cells, Cultured | 2002 |
Synthesis and structure-activity relationships of 5,6,7,8-tetrahydropyrido[3,4-b]pyrazine-based hydroxamic acids as HB-EGF shedding inhibitors.
Topics: Epidermal Growth Factor; Heparin-binding EGF-like Growth Factor; Humans; Hydroxamic Acids; Intercellular Signaling Peptides and Proteins; Protease Inhibitors; Pyrazines; Stereoisomerism; Structure-Activity Relationship; Sulfonamides; Tumor Cells, Cultured | 2003 |
[Gene expression profile changes in human multiple myeloma].
Topics: Adult; Aged; Boronic Acids; Bortezomib; Epidermal Growth Factor; Female; Gene Expression; Gene Expression Profiling; Heparin-binding EGF-like Growth Factor; Humans; Intercellular Signaling Peptides and Proteins; Male; Middle Aged; Multiple Myeloma; Nuclear Proteins; Oligonucleotide Array Sequence Analysis; Protein Tyrosine Phosphatases; Pyrazines; RNA, Messenger | 2003 |
Proteasome inhibition blocks ligand-induced dynamic processing and internalization of epidermal growth factor receptor via altered receptor ubiquitination and phosphorylation.
Topics: Boronic Acids; Bortezomib; Epidermal Growth Factor; ErbB Receptors; Genes, Reporter; HeLa Cells; Humans; Luciferases, Firefly; Microscopy, Fluorescence; Phosphorylation; Protease Inhibitors; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrazines; Recombinant Fusion Proteins; Transfection; Ubiquitination | 2009 |
Regulation of PSMB5 protein and β subunits of mammalian proteasome by constitutively activated signal transducer and activator of transcription 3 (STAT3): potential role in bortezomib-mediated anticancer therapy.
Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Boronic Acids; Bortezomib; Cell Line, Tumor; Epidermal Growth Factor; HEK293 Cells; HeLa Cells; Humans; Neoplasms; Phosphorylation; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Subunits; Pyrazines; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; STAT3 Transcription Factor; Tyrosine; Up-Regulation | 2014 |
Piezo1 activation using Yoda1 inhibits macropinocytosis in A431 human epidermoid carcinoma cells.
Topics: Biological Transport; Calcium; Carcinoma, Squamous Cell; Cell Line, Tumor; Epidermal Growth Factor; Humans; Ion Channels; Pinocytosis; Pyrazines; Thiadiazoles | 2022 |