pyrazines has been researched along with dimethylnitrosamine in 5 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (80.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ha, JR; Kang, KW; Kim, CW; Kim, ND; Kim, SG | 1 |
| Choi, SH; Ha, JR; Kang, KW; Kim, CW; Kim, SG | 1 |
| Bae, SK; Kim, SG; Lee, I; Lee, JY; Lee, MG; Lee, SJ; Lee, Y | 1 |
| Bae, SK; Kim, JW; Kim, SG; Kim, T; Lee, I; Lee, MG; Lee, SJ | 1 |
| Brown, LC; Cummings, ME; Li, L; Patel, Y; Pegg, AE; Peterson, LA; Stram, DO; Urban, AM; Vu, CC; Warmka, JK; Wattenberg, EV | 1 |
5 other study(ies) available for pyrazines and dimethylnitrosamine
| Article | Year |
|---|---|
2-(Allylthio)pyrazine, a cancer chemopreventive agent, inhibits liver fibrosis induced by dimethylnitrosamine in rats: role of inhibition of transforming growth factor-beta1 expression.
Topics: Animals; Dimethylnitrosamine; Enzyme Inhibitors; Liver; Liver Cirrhosis; Male; Pyrazines; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Transaminases; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2001 |
Inhibition of dimethylnitrosamine-induced liver fibrosis by [5-(2-pyrazinyl)-4-methyl-1,2-dithiol-3-thione] (oltipraz) in rats: suppression of transforming growth factor-beta1 and tumor necrosis factor-alpha expression.
Topics: Animals; Base Sequence; Dimethylnitrosamine; DNA Primers; Glyceraldehyde-3-Phosphate Dehydrogenases; Liver Cirrhosis, Experimental; Pyrazines; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thiones; Thiophenes; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2002 |
Pharmacokinetic changes of oltipraz after intravenous and oral administration to rats with liver cirrhosis induced by dimethylnitrosamine.
Topics: Administration, Oral; Animals; Area Under Curve; Blood Proteins; Dimethylnitrosamine; Injections, Intravenous; Liver Cirrhosis, Experimental; Male; Microsomes, Liver; Protein Binding; Pyrazines; Rats; Rats, Sprague-Dawley; Schistosomicides; Thiones; Thiophenes; Time Factors; Tissue Distribution | 2004 |
Pharmacokinetics and therapeutic effects of oltipraz after consecutive or intermittent oral administration in rats with liver cirrhosis induced by dimethylnitrosamine.
Topics: Administration, Oral; Alkylating Agents; Animals; Area Under Curve; Chromatography, High Pressure Liquid; Creatinine; Dimethylnitrosamine; Half-Life; Hematocrit; Liver; Liver Cirrhosis; Male; Organ Size; Pyrazines; Rats; Rats, Wistar; Schistosomicides; Thiones; Thiophenes | 2006 |
Role of aldehydes in the toxic and mutagenic effects of nitrosamines.
Topics: Aldehydes; Animals; CHO Cells; Cricetinae; Cricetulus; Dimethylnitrosamine; DNA Adducts; DNA Damage; DNA Methylation; Humans; Models, Chemical; Mutagenicity Tests; Nitrosamines; Nitrosomethylurethane; O(6)-Methylguanine-DNA Methyltransferase; Pyrazines | 2013 |