pyrazines has been researched along with coelenterazine in 199 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (1.51) | 18.7374 |
| 1990's | 19 (9.55) | 18.2507 |
| 2000's | 62 (31.16) | 29.6817 |
| 2010's | 83 (41.71) | 24.3611 |
| 2020's | 32 (16.08) | 2.80 |
| Authors | Studies |
|---|---|
| Johnson, FH; Shimomura, O | 1 |
| Lucas, M; Solano, F | 1 |
| Campbell, AK; Knight, MR; Smith, SM; Trewavas, AJ | 1 |
| Campbell, AK; Compston, DA; Frith, S; Houston, WA; Morgan, BP; Patel, A; Scolding, NJ | 1 |
| Kishi, Y; Musicki, B; Shimomura, O | 1 |
| Brownstein, M; Button, D | 1 |
| Badminton, MN; Campbell, AK; Kendall, JM; Sala-Newby, G | 1 |
| Bondaŕ, VS; Frank, LA; Illarionov, BA; Markova, SV; Trofimov, CP; Vysotski, ES | 1 |
| Shimomura, O | 3 |
| Campbell, AK; Watkins, NJ | 1 |
| Inouye, S; Kishi, Y; Shimomura, O | 1 |
| Campbell, AK; Knight, MR; Read, ND; Trewavas, AJ | 1 |
| Badminton, MN; Campbell, AK; Kendall, JM; Sala-Newby, GB | 1 |
| Badminton, MN; Campbell, AK; Kendall, JM; Rembold, CM; Sala-Newby, GB | 1 |
| Gonzalez-Trueba, G; Paradisi, C; Zoratti, M | 1 |
| Inouye, S; Shimomura, O | 1 |
| Shimomura, O; Teranishi, K | 2 |
| Jubin, R; Murray, MG | 1 |
| Alakhov, YB; Berestovskaya, NG; Bondar, VS; Gorokhovatsky, AY; Maximov, JE; Shaloiko, LA; von Doehren, H; Vysotski, ES | 1 |
| Freeman, BA; Radi, R; Richardson, G; Suarez, E; Tarpey, MM; White, CR | 1 |
| Hibbert, F; Jones, K; Keenan, M | 1 |
| Head, JF; Inouye, S; Shimomura, O; Teranishi, K | 1 |
| Baguet, F; de Wergifosse, B; Dubuisson, ML; Marchand-Brynaert, J; Rees, JF; Trouet, A | 1 |
| Anastacio, VM; Augusto, O; da Luz, PL; Junqueira, ML; Krieger, JE; Laurindo, FR; Pereira, AC; Souza, HP; Souza, LC | 1 |
| Inouye, S; Nakamura, H; Shimomura, O; Watanabe, K | 1 |
| Inouye, S | 2 |
| Chen, CJ; Lee, J; Liu, ZJ; Rose, JP; Vysotski, ES; Wang, BC | 1 |
| Inouye, S; Murai, A; Nakamura, H; Wu, C | 1 |
| De Tollenaere, C; de Wergifosse, B; Devillers, I; Dive, G; Falmagne, B; Marchand-Brynaert, J; Rees, JF | 1 |
| Ainscow, EK; Mitchell, KJ; Pinton, P; Pozzan, T; Rizzuto, R; Rutter, GA; Tacchetti, C; Varadi, A | 1 |
| Haddock, SH; Rivers, TJ; Robison, BH | 1 |
| Bryan, B; Flood, PR; Inouye, S; Shimomura, A; Shimomura, O | 1 |
| Bhaumik, S; Gambhir, SS | 1 |
| Kakoi, H | 1 |
| Johnstone, L; Myint, AT; Raha, S; Robinson, BH | 1 |
| Plieth, C; Trewavas, AJ | 1 |
| Tsuji, FI | 1 |
| Janssens, BJ; Marchand-Brynaert, J; Rees, JF | 1 |
| Arrault, A; Bouskela, E; Cordi, A; Dubuisson, M; Gharbi, S; Marchand, C; Marchand-Brynaert, J; Rees, JF; Rupin, A; Verbeuren, T | 1 |
| Burton, M; Cavalier, JF; De Tollenaere, C; Dussart, F; Marchand, C; Marchand-Brynaert, J; Rees, JF | 1 |
| Chatterjee, P; Hu, L; Li, WG; Miller, FJ; Oberley, LW; Rice, JB; Spector, AA; Stoll, LL; Weintraub, NL; Xu, SP | 1 |
| Blinks, JR; Deng, L; Frank, LA; Herko, M; Lee, J; Liu, ZJ; Malikova, NP; Markova, SV; Rose, JP; Vysotski, ES; Wang, BC | 1 |
| Grigliatti, TA; Knight, PJ; Pfeifer, TA | 1 |
| Deng, L; Lee, J; Liu, ZJ; Rose, J; Vysotski, ES; Wang, BC | 1 |
| Finel, M; Hassinen, IE; Kervinen, M; Pätsi, J | 1 |
| Pichler, A; Piwnica-Worms, D; Prior, JL | 1 |
| de Wergifosse, B; Dubuisson, M; Marchand-Brynaert, J; Rees, JF; Trouet, A | 1 |
| Cao, Y; Contag, CH; Doyle, TC; Piwnica-Worms, D; Stevenson, DK; Wong, RJ; Zhao, H | 1 |
| Inouye, S; Kato, S; Oba, Y; Ojika, M; Tsuduki, H | 1 |
| Ferbitz, L; Fuhrmann, M; Hausherr, A; Hegemann, P; Heitzer, M; Schödl, T | 1 |
| Chong, KT; Inouye, S; Nakagawa, A; Shimomura, O; Teranishi, K; Toma, S | 1 |
| Grigliatti, TA; Knight, PJ | 1 |
| Darley-Usmar, VM; Landar, A; Le Goffe, C; Moellering, DR; Ramachandran, A; Zmijewski, JW | 1 |
| Dubuisson, ML; Marchand-Brynaert, J; Rees, JF | 1 |
| Dalrymple, MB; Dromey, JR; Eidne, KA; Lim, EM; Pfleger, KD; Thomas, WG | 1 |
| Frangioni, JV | 1 |
| Inouye, S; Sasaki, S | 2 |
| Cheung, CY; Meng, A; Miller, AL; Webb, SE | 1 |
| Teranishi, K | 1 |
| Gambhir, SS; Loening, AM; Rao, J; So, MK | 1 |
| Bovolenta, S; Corazza, S; Foti, M; Lohmer, S | 1 |
| Bönisch, H; Brüss, M; Combrink, S; Göthert, M; Niesler, B; Walstab, J | 1 |
| Fenn, TD; Gambhir, SS; Loening, AM | 1 |
| Frank, LA; Lee, J; Malikova, NP; Markova, SV; Stepanyuk, GA; Titushin, MS; Vysotski, ES | 1 |
| Howell, MH; von Arnim, AG; Woo, J | 1 |
| Daunert, S; Ensor, CM; Teasley Hamorsky, K; Wei, Y | 1 |
| Frank, LA; Lee, J; Liu, ZJ; Markova, SS; Stepanyuk, GA; Vysotski, ES; Wang, BC | 1 |
| Campbell, S; Cissell, KA; Deo, SK | 1 |
| Lee, J; Liu, ZJ; Rose, JP; Stepanyuk, GA; Vysotski, ES; Wang, BC | 1 |
| Brini, M | 1 |
| Combs, K; Daunert, S; Deo, S; Ensor, C; Qu, X; Rowe, L | 1 |
| Babu, PS; Christoffersen, CT; Jones, KA; Jorgensen, VH; Menon, V; Ranganathn, A; Sabio, M; Uberti, MA | 1 |
| Daunert, S; Deo, SK; Dikici, E; Ensor, M; Logue, C; Millner, L; Qu, X; Rowe, L | 1 |
| Eremeeva, EV; Markova, SV; van Berkel, WJ; Visser, AJ; Vysotski, ES; Westphal, AH | 1 |
| Afanasev, I | 1 |
| Gupta, M; Luker, G; Luker, K | 1 |
| Bresser, T; Knochel, P; Mosrin, M | 1 |
| Inouye, S; Kato, S; Oba, Y; Ojika, M | 1 |
| Isobe, H; Okumura, M; Yamaguchi, K; Yamanaka, S | 1 |
| Daunert, S; Ensor, M; Mehl, R; Rowe, L | 1 |
| Hiraoka, K; Kasahara, N; Kimura, T; Logg, CR | 1 |
| Lee, J; Malikova, NP; Markova, SV; Stepanyuk, GA; Unch, J; Vysotski, ES | 1 |
| Hisada, S; Hosoya, T; Iimori, R; Inouye, S; Sahara, Y | 1 |
| Plieth, C; Saleh, L | 1 |
| Karplus, E; Miller, AL; Rogers, KL; Webb, SE | 1 |
| Ahn, BC; Bae, SA; Ha, JH; Jeon, YH; Lee, J; Lee, SW; Lee, YJ; Lee, YL; Yoon, GS | 1 |
| Inouye, S; Kanamori, T; Kondo, C; Suzuki, T | 1 |
| Blasberg, RG; Huang, R; Serganova, I; Vider, J | 1 |
| Inoue, Y; Izawa, K; Kiryu, S; Ohtomo, K; Ratanakanit, H; Sheng, F; Tojo, A; Watanabe, M | 1 |
| Chan, CT; De, A; Dragulescu-Andrasi, A; Gambhir, SS; Massoud, TF | 1 |
| Aghamaali, MR; Hassannia, S; Hosseinkhani, S; Jafarian, V; Sajedi, RH; Sariri, R; Taghdir, M | 1 |
| Frank, LA; Korneeva, SI; Krasitskaya, VV; Kudryavtsev, AN; Markova, SV; Stepanyuk, GA | 1 |
| Hirano, T | 1 |
| Bovenberg, MS; Degeling, MH; Tannous, BA | 1 |
| Feng, Y; Lee, J; Liu, ZJ; Titushin, MS; Vysotski, ES | 1 |
| Morse, D; Tannous, BA | 1 |
| Balivada, S; Basel, MT; Bossmann, SH; Kalita, M; Moore, D; Pyle, M; Rachakatla, RS; Seo, GM; Shinogle, H; Shrestha, TB; Thapa, PS; Troyer, DL; Villanueva, D; Wang, H | 1 |
| Bhattacharyya, S; Miller, SC; Quiñones, GA; Sobek, D; Stephan, JP | 1 |
| Schildkraut, E; Schildkraut, I; Tzertzinis, G | 1 |
| Chan, CT; Chiosis, G; Gambhir, SS; Geller, R; Hoehne, A; Massoud, TF; Paulmurugan, R; Reeves, RE; Solow-Cordero, DE; Yaghoubi, SS | 1 |
| Bachas, L; Daunert, S; Dikici, E; Ensor, CM; Pasini, P; Teasley Hamorsky, K | 1 |
| Eremeeva, EV; van Berkel, WJ; van Mierlo, CP; Vysotski, ES; Westphal, AH | 1 |
| Hasegawa, M; Jin, T; Ohyanagi, T; Tsukasaki, Y | 1 |
| Fahad, AS; Feugang, JM; Greene, JM; Monroe, WA; Ryan, PL; Willard, ST; Youngblood, RC | 1 |
| Haddock, SH; McDermott, AG; Powers, ML; Shaner, NC | 1 |
| Hosoya, T; Iimori, R; Inouye, S; Sahara-Miura, Y; Sato, J; Yoshida, S | 1 |
| Eremeeva, EV; Liu, ZJ; Natashin, PV; Song, L; van Berkel, WJ; Vysotski, ES; Zhou, Y | 1 |
| Chan, CM; Miller, AL; Webb, SE | 1 |
| Hosoya, T; Inouye, S; Kurakata, H; Sahara-Miura, Y; Sato, J; Yoshida, S | 1 |
| Burakova, LP; Lee, J; Liu, ZJ; Rose, J; Stepanyuk, GA; Vysotski, ES; Wang, BC | 1 |
| Eremeeva, EV; Markova, SV; van Berkel, WJ; Vysotski, ES | 1 |
| Ibata, K; Kikuchi, K; Lindberg, E; Miyawaki, A; Mizukami, S | 1 |
| Bononi, A; Bonora, M; Giorgi, C; Marchi, S; Patergnani, S; Pinton, P; Rimessi, A; Rizzuto, R | 1 |
| Inouye, S; Sahara-Miura, Y | 1 |
| Granatiero, V; Merli, G; Patron, M; Rizzuto, R; Tosatto, A | 1 |
| Iyengar, R; Luker, GD; Luker, KE; Moudgil, P; Nyati, S; Rehemtulla, A; Stacer, AC | 1 |
| Burakova, LP; Eremeeva, EV; Frank, LA; Krasitskaya, VV; Kudryavtsev, AN; Shimomura, O | 1 |
| Hosoya, T; Inouye, S; Sahara-Miura, Y; Sato, J; Yoshida, S | 1 |
| Borgdorff, AJ; Brûlet, P; Burakova, LP; Dodd, RH; Gealageas, R; Malikova, NP; Picaud, S; Vysotski, ES | 1 |
| Citterio, D; Hoshino, E; Iwasawa, N; Nishihara, R; Nishiyama, S; Saitoh, T; Sato, M; Suganuma, S; Suzuki, H; Suzuki, K | 1 |
| Christianson, LM; Francis, WR; Haddock, SH; Powers, ML; Shaner, NC | 1 |
| Hosoya, T; Iimori, R; Inouye, S; Sahara-Miura, Y; Sato, J; Sumida, Y; Yoshida, S | 1 |
| Coste, AT; Delarze, E; Ischer, F; Sanglard, D | 1 |
| Mehle, A | 1 |
| Coutant, EP; Janin, YL | 1 |
| Alonso, MT; Aulestia, FJ; García-Sancho, J; Rodríguez-Prados, M; Rojo-Ruiz, J | 1 |
| Bronsart, LL; Contag, CH; Stokes, C | 2 |
| Borgdorff, AJ; Malikova, NP; Vysotski, ES | 1 |
| Markova, SV; Vysotski, ES | 1 |
| Ehara, H; Hosoya, T; Inouye, S; Sekine, SI; Shirouzu, M; Tomabechi, Y | 1 |
| Eremeeva, EV; van Berkel, WJ; Vysotski, ES | 1 |
| Bronsart, L; Contag, C; Habtezion, A; Nguyen, L | 1 |
| Du, L; Jiang, T; Li, M | 1 |
| Burakova, LP; Eremeeva, EV; Stepanyuk, GA; Vysotski, ES | 1 |
| Esteves da Silva, JC; Magalhães, CM; Pinto da Silva, L | 1 |
| Jiang, T; Li, M; Yang, X; Yuan, M; Zhang, H; Zhang, T | 1 |
| Carvalho, LA; Kantar, RS; Lashgari, G; Lewandrowski, GK; Tabet, EI; Tannous, BA | 1 |
| Citterio, D; Nishihara, R; Suzuki, K | 1 |
| Chan, HY; Cheung, MC; Gao, Y; Miller, AL; Webb, SE | 1 |
| Dinesh-Kumar, SP; Hong, J; Woo, J | 1 |
| Abe, M; Citterio, D; Kim, SB; Nishihara, R; Nishiyama, S; Suzuki, K | 1 |
| Ferreira, PJO; Min, CG; Pinto da Silva, L | 1 |
| English, AW; Gross, RE; Jaiswal, PB; Tung, JK | 1 |
| Ding, K; Gross, RE; Shiu, FH; Tung, JK | 1 |
| Hall, MP; Kirkland, TA; Machleidt, T; Shakhmin, A; Walker, JR; Wood, KV | 1 |
| Ferré, S; Sánchez-Soto, M; Yano, H | 1 |
| Du, L; Jiang, T; Li, M; Li, Z; Yang, X | 1 |
| Brown, TM; Dorka, N; Hochgeschwender, U; Medendorp, WE; Palmateer, B; Petersen, ED; Prakash, M; Wagner, LM; Zenchak, JR | 1 |
| Citterio, D; Hoshino, E; Iwasawa, N; Kakudate, Y; Kim, SB; Kishigami, S; Nakajima, T; Nishihara, R; Nishiyama, S; Sasaki, SI; Sato, M; Suzuki, K | 1 |
| Armstrong, JD; Davies, RW; Lagogiannis, K; Marescotti, M; Webb, B | 1 |
| Cheng, L; Dong, G; Du, L; Han, G; Li, M; Li, X; Tang, C; Yang, X; Zhang, C; Zhou, Y | 1 |
| Ahn, BC; Baek, SH; Gangadaran, P; Hong, CM; Jeong, SY; Kalimuthu, SK; Lee, HW; Lee, J; Lee, SW; Li, XJ; Min, OJ; Rajendran, RL; Zhu, L | 1 |
| Esteves da Silva, JCG; Magalhães, CM; Pinto da Silva, L | 2 |
| Ai, HW; Yeh, HW | 1 |
| Baatallah, R; Coutant, EP; Gagnot, G; Goyard, S; Hervin, V; Jacob, Y; Janin, YL; Rose, T | 1 |
| Bouvier, M; Kobayashi, H; Picard, LP; Schönegge, AM | 1 |
| Abe, M; Citterio, D; Ikeda, Y; Iwasawa, N; Kim, SB; Nakajima, T; Nishihara, R; Nishiyama, S; Paulmurugan, R; Sato, M; Suzuki, K | 1 |
| Daunert, S; Deo, S; Dikici, E; Joel, S; Scott, D; Yu, X | 1 |
| Afjei, R; Citterio, D; Hiruta, Y; Iwasawa, N; Kim, SB; Nakajima, T; Natarajan, A; Nishihara, R; Nishiyama, S; Paulmurugan, R; Sato, M; Suzuki, K; Yamamoto, E | 1 |
| Citterio, D; Hiruta, Y; Iwasawa, N; Kim, SB; Nakajima, T; Nishihara, R; Nishiyama, S; Nomura, N; Sato, M; Suzuki, K | 1 |
| Cabañas, C; Cardeñes, B; López-Martín, S; Morales, S; Toribio, V; Yáñez-Mó, M | 1 |
| Duarte, D; Esteves da Silva, JCG; Ferreira, PJO; Magalhães, CM; Núñez-Montenegro, A; Pinto da Silva, L; Rodríguez-Borges, JE; Vale, N | 1 |
| Duarte, D; Esteves da Silva, JCG; Ferreira, PJO; González-Berdullas, P; Magalhães, CM; Núnez-Montenegro, A; Pinto da Silva, L; Rodríguez-Borges, JE; Vale, N | 1 |
| Friedman, NG; Gomez-Ramirez, M; Hochgeschwender, U; Moore, CI; More, AI | 1 |
| Berglund, K; Gross, RE; Tung, JK; Wang, Z; Wei, L; Yu, SP; Zhang, JY | 1 |
| Asada, H; Iwasaka, M; Muneyama, E; Oba, Y; Paitio, J; Takei, S; Yano, D | 1 |
| Broyles, D; Daunert, S; Deo, SK; Dikici, E; Joda, H; Kaifer, A; Kaur, A; Moutsiopoulou, A | 1 |
| Ding, BW; Eremeeva, EV; Liu, YJ; Vysotski, ES | 1 |
| Inouye, S; Kanamori, T; Suzuki, T | 1 |
| Eremeeva, EV; Jiang, T; Li, M; Malikova, NP; Vysotski, ES | 1 |
| Love, AC; Prescher, JA | 1 |
| Bashmakova, EE; Frank, LA; Krasitskaya, VV | 1 |
| Dobi, KC; Gaffney, JP; Galbraith, M; Gruber, DF; Guarnaccia, A; Gujarati, NA; Mirza, JD; Oliveira, AG; Pieribone, VA; Sparks, JS; Tessler, M; Wood, RJ | 1 |
| Benfenati, F; Blancafort, L; Cappelli, A; Cesca, F; Giuliani, G; Merolla, A; Paolino, M; Reale, A; Saletti, M | 1 |
| Citterio, D; Eguchi, M; Hiruta, Y; Ikeda, Y; Mizui, Y; Ozawa, T; Tanaka, M; Yoshimura, H | 1 |
| Kobayashi, N; Kuroda, Y; Saotome, T; Tsuda, K; Unzai, S; Wu, N; Yamazaki, T | 1 |
| Kurita, R; Nishihara, R; Niwa, K; Tomita, T | 1 |
| Corneliussen, AS; Didriksen, AK; Dijkema, FM; Nordentoft, MK; Willemoës, M; Winther, JR | 1 |
| Abe, M; Kim, SB; Nishihara, R; Suzuki, K | 2 |
| Kim, SB; Nishihara, R; Paulmurugan, R; Suzuki, K | 1 |
| Berglund, K; Carrasco, D; English, AW; Goebel, K; Gross, RE; Isaacson, R; Mistretta, OC; Wynans, C | 1 |
| Kurita, R; Nishihara, R | 1 |
| Endo, H; Mizuno, G; Oba, Y; Paitio, J; Yano, D | 1 |
| Hosoya, T; Inouye, S; Nakamura, M | 1 |
| Jiang, T; Li, M | 1 |
| Esteves da Silva, JCG; González-Berdullas, P; Magalhães, CM; Pinto da Silva, L; Sousa, J | 1 |
| Hosoya, T; Inouye, S; Sahara-Miura, Y; Sato, JI; Sekine, SI; Shirouzu, M; Sumida, Y; Tomabechi, Y | 1 |
| Baker, B; Benner, J; Brown, E; Corrêa, IR; Ettwiller, L; McClung, C; Schildkraut, I; Tzertzinis, G | 1 |
| Furuta, T; Hirano, T; Kamiya, G; Kim, SB; Kitada, N; Maki, S | 1 |
| Furuta, T; Hirano, T; Kamiya, G; Kim, SB; Kitada, N; Maki, SA | 1 |
| Furuta, T; Kamiya, G; Kim, SB; Kitada, N; Maki, SA | 1 |
14 review(s) available for pyrazines and coelenterazine
| Article | Year |
|---|---|
Glowing jellyfish, luminescence and a molecule called coelenterazine.
Topics: Aequorin; Animals; Firefly Luciferin; Green Fluorescent Proteins; Imidazoles; Luminescent Measurements; Luminescent Proteins; Models, Chemical; Pyrazines; Scyphozoa | 1999 |
Coelenterazine (marine bioluminescent substrate): a source of inspiration for the discovery of novel antioxidants.
Topics: Animals; Antioxidants; Drug Design; Hemolysis; Humans; Imidazoles; Lipid Peroxidation; Neuroprotective Agents; Oxidation-Reduction; Oxidative Stress; Peroxynitrous Acid; Pyrazines; Radiation-Protective Agents; Reactive Oxygen Species; Superoxides | 2005 |
Luminescence of imidazo[1,2-a]pyrazin-3(7H)-one compounds.
Topics: Aequorin; Imidazoles; Luminescence; Luminescent Agents; Models, Chemical; Molecular Structure; Pyrazines; Reactive Oxygen Species; Water | 2007 |
Detection of superoxide in cells, tissues and whole organisms.
Topics: Acridines; Cytochromes c; Imidazoles; Luminescent Measurements; Luminol; Oxygen; Pyrazines; Spectrophotometry; Spin Trapping; Superoxides | 2009 |
The reaction mechanism of calcium-activated photoprotein bioluminescence.
Topics: Calcium; Imidazoles; Light; Luminescent Agents; Luminescent Measurements; Luminescent Proteins; Oxygen; Pyrazines | 2012 |
Protein-protein complexation in bioluminescence.
Topics: Animals; Anthozoa; Aquatic Organisms; Bacteria; Binding Sites; Calcium; Crystallography, X-Ray; Fluorescence Resonance Energy Transfer; Green Fluorescent Proteins; Hydrozoa; Imidazoles; Luciferases; Luminescent Measurements; Luminescent Proteins; Models, Molecular; Protein Binding; Pteridines; Pyrazines; Scyphozoa; Spectrometry, Fluorescence | 2011 |
Synthetic Routes to Coelenterazine and Other Imidazo[1,2-a]pyrazin-3-one Luciferins: Essential Tools for Bioluminescence-Based Investigations.
Topics: Firefly Luciferin; Humans; Imidazoles; Luciferases; Luminescence; Luminescent Measurements; Luminescent Proteins; Pyrazines | 2015 |
Coelenterazine-dependent luciferases.
Topics: Animals; Imidazoles; Luciferases; Luminescent Proteins; Pyrazines | 2015 |
Lighting up bioluminescence with coelenterazine: strategies and applications.
Topics: Imidazoles; Luciferases; Luminescence; Membrane Fusion; Pyrazines | 2016 |
Chemiluminescence and Bioluminescence as an Excitation Source in the Photodynamic Therapy of Cancer: A Critical Review.
Topics: Animals; Firefly Luciferin; Humans; Imidazoles; Luciferases, Firefly; Luciferases, Renilla; Luminescence; Luminescent Agents; Luminol; Neoplasms; Photochemotherapy; Photosensitizing Agents; Pyrazines; Reactive Oxygen Species | 2016 |
Development and Applications of Bioluminescent and Chemiluminescent Reporters and Biosensors.
Topics: Animals; Benzothiazoles; Biosensing Techniques; Humans; Imidazoles; Luciferases; Luminescent Agents; Luminescent Measurements; Optical Imaging; Pyrazines | 2019 |
[Novel Technology for Studying Insulin Secretion: Imaging and Quantitative Analysis by a Bioluminescence Method].
Topics: Animals; Cell Communication; Cell Line; Cells, Cultured; Humans; Imidazoles; Insulin Secretion; Insulin-Secreting Cells; Luciferases; Luminescent Measurements; Molecular Imaging; Pyrazines; Rats | 2020 |
Seeing (and Using) the Light: Recent Developments in Bioluminescence Technology.
Topics: Animals; Channelrhodopsins; Firefly Luciferin; Imidazoles; Light; Luciferases; Luminescent Measurements; Microscopy, Fluorescence; Neoplasms; Optical Imaging; Pyrazines | 2020 |
Coelenterazine-Dependent Luciferases as a Powerful Analytical Tool for Research and Biomedical Applications.
Topics: Calcium; Enzyme Activation; Firefly Luciferin; Gene Expression; Genes, Reporter; Imidazoles; Luciferases; Luminescent Measurements; Luminescent Proteins; Oxidative Stress; Pyrazines; Research | 2020 |
185 other study(ies) available for pyrazines and coelenterazine
| Article | Year |
|---|---|
Peroxidized coelenterazine, the active group in the photoprotein aequorin.
Topics: Aequorin; Apoproteins; Binding Sites; Imidazoles; Luminescent Measurements; Mass Spectrometry; Oxidation-Reduction; Peroxides; Pigments, Biological; Proteins; Pyrazines | 1978 |
Coelenterazine is a superoxide anion-sensitive chemiluminescent probe: its usefulness in the assay of respiratory burst in neutrophils.
Topics: Aequorin; Azides; Cytochalasin B; Humans; Imidazoles; In Vitro Techniques; Indicators and Reagents; Kinetics; Luminescent Measurements; Luminol; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidation-Reduction; Pyrazines; Superoxides | 1992 |
Recombinant aequorin as a probe for cytosolic free Ca2+ in Escherichia coli.
Topics: Aequorin; Anti-Bacterial Agents; Apoproteins; Calcium; Complement System Proteins; Escherichia coli; Humans; Imidazoles; In Vitro Techniques; Luminescence; Neutrophils; Pyrazines; Recombinant Proteins; Transformation, Genetic | 1991 |
Photoproteins as indicators of intracellular free Ca2+.
Topics: Aequorin; Animals; Apoproteins; Biological Evolution; Calcium; Cloning, Molecular; Complement System Proteins; Humans; Imidazoles; In Vitro Techniques; Indicators and Reagents; Liposomes; Luminescent Measurements; Luminescent Proteins; Neutrophils; Pyrazines; RNA, Messenger | 1989 |
Semi-synthetic aequorin. An improved tool for the measurement of calcium ion concentration.
Topics: Aequorin; Animals; Calcium; Imidazoles; Kinetics; Luminescent Measurements; Luminescent Proteins; Pyrazines; Scyphozoa; Spectrophotometry | 1988 |
Aequorin-expressing mammalian cell lines used to report Ca2+ mobilization.
Topics: Aequorin; Animals; Calcium; Cells, Cultured; CHO Cells; Cricetinae; Feasibility Studies; Gene Expression Regulation; Humans; Imidazoles; Kidney; Ligands; Luminescent Measurements; Pyrazines; Substance P; Transfection | 1993 |
Nucleoplasmin-targeted aequorin provides evidence for a nuclear calcium barrier.
Topics: Aequorin; Amino Acid Sequence; Animals; Antigens, Viral, Tumor; Apoproteins; Base Sequence; Calcium; Cell Line; Cell Membrane Permeability; Cell Nucleus; Complement Membrane Attack Complex; Cytosol; Imidazoles; Luminescent Measurements; Molecular Sequence Data; Nuclear Proteins; Nucleoplasmins; Phosphoproteins; Pyrazines; Recombinant Fusion Proteins | 1995 |
Mn(2+)-activated luminescence of the photoprotein obelin.
Topics: Aequorin; Animals; Cnidaria; Dose-Response Relationship, Drug; Free Radical Scavengers; Free Radicals; Hydrogen-Ion Concentration; Imidazoles; Kinetics; Light; Luminescent Measurements; Luminescent Proteins; Manganese; Models, Chemical; Pyrazines; Recombinant Proteins; Sulfhydryl Reagents; Thiosulfates | 1995 |
Cause of spectral variation in the luminescence of semisynthetic aequorins.
Topics: Aequorin; Calcium; Deuterium; Electrochemistry; Imidazoles; Luminescent Measurements; Molecular Conformation; Oxygen; Photometry; Pyrazines; Spectrometry, Fluorescence | 1995 |
Requirement of the C-terminal proline residue for stability of the Ca(2+)-activated photoprotein aequorin.
Topics: Aequorin; Animals; Base Sequence; Calcium; DNA; Electrophoresis, Agar Gel; Glutamates; Glutamic Acid; Histidine; Imidazoles; In Vitro Techniques; Luminescent Measurements; Molecular Sequence Data; Mutation; Polymerase Chain Reaction; Proline; Protein Biosynthesis; Pyrazines; Recombinant Proteins; Scyphozoa | 1993 |
The relative rate of aequorin regeneration from apoaequorin and coelenterazine analogues.
Topics: Aequorin; Apoproteins; Calcium-Binding Proteins; Imidazoles; Pyrazines; Recombinant Proteins | 1993 |
Imaging calcium dynamics in living plants using semi-synthetic recombinant aequorins.
Topics: Aequorin; Calcium; Calibration; Cold Temperature; Image Processing, Computer-Assisted; Imidazoles; Kinetics; Luminescent Measurements; Molecular Structure; Nicotiana; Plants, Toxic; Pyrazines; Recombinant Proteins | 1993 |
Differences in stability of recombinant apoaequorin within subcellular compartments.
Topics: Aequorin; Apoproteins; Cytosol; Endoplasmic Reticulum; HeLa Cells; Humans; Imidazoles; Pyrazines; Recombinant Proteins | 1995 |
Recombinant apoaequorin acting as a pseudo-luciferase reports micromolar changes in the endoplasmic reticulum free Ca2+ of intact cells.
Topics: Adenosine Triphosphate; Aequorin; Apoproteins; Calcium; Endoplasmic Reticulum; HeLa Cells; Humans; Imidazoles; Ionomycin; Kinetics; Luciferases; Luminescent Measurements; Pyrazines; Recombinant Proteins; Sensitivity and Specificity; Time Factors | 1996 |
Synthesis of coelenterazine.
Topics: Aequorin; Imidazoles; Pyrazines | 1996 |
The use of Renilla luciferase, Oplophorus luciferase, and apoaequorin as bioluminescent reporter protein in the presence of coelenterazine analogues as substrate.
Topics: Aequorin; Animals; Apoproteins; Calcium-Binding Proteins; Cnidaria; Decapoda; Firefly Luciferin; Imidazoles; Indicators and Reagents; Luciferases; Luminescent Measurements; Molecular Weight; Pyrazines; Recombinant Proteins; Scyphozoa; Substrate Specificity | 1997 |
Coelenterazine analogs as chemiluminescent probe for superoxide anion.
Topics: Aequorin; Firefly Luciferin; Hypoxanthine; Imidazoles; Luminescent Measurements; Molecular Structure; Pyrazines; Sensitivity and Specificity; Solubility; Structure-Activity Relationship; Superoxides; Xanthine Oxidase | 1997 |
Membrane permeability of coelenterazine analogues measured with fish eggs.
Topics: Aequorin; Animals; Cell Membrane Permeability; Dose-Response Relationship, Drug; Firefly Luciferin; Imidazoles; Intracellular Fluid; Killifishes; Ovum; Pyrazines | 1997 |
Activity screening of bacteria containing Renilla luciferase plasmids.
Topics: Animals; Cloning, Molecular; Cnidaria; Coleoptera; Escherichia coli; Firefly Luciferin; Gene Expression; Genes, Reporter; Imidazoles; Luciferases; Luminescent Measurements; Plasmids; Protein Biosynthesis; Pyrazines; Rabbits; Reticulocytes | 1998 |
Cotranslational formation of active photoprotein obelin in a cell-free translation system: direct ultrahigh sensitive measure of the translation course.
Topics: Cell-Free System; Imidazoles; Luminescent Measurements; Luminescent Proteins; Protein Biosynthesis; Protein Folding; Pyrazines; RNA, Messenger; Time Factors | 1999 |
Chemiluminescent detection of oxidants in vascular tissue. Lucigenin but not coelenterazine enhances superoxide formation.
Topics: Acetylcholine; Acridines; Animals; Cells, Cultured; Cytochrome c Group; Endothelium, Vascular; Firefly Luciferin; Hydrogen Peroxide; Imidazoles; Luminescent Measurements; Male; NAD; Nitrates; Oxidants; Oxygen Consumption; Pyrazines; Rats; Rats, Sprague-Dawley; Superoxides; Vasodilator Agents; Xanthine Oxidase | 1999 |
The crystal structure of the photoprotein aequorin at 2.3 A resolution.
Topics: Aequorin; Animals; Calcium; Crystallography, X-Ray; Escherichia coli; Imidazoles; Ligands; Models, Molecular; Molecular Sequence Data; Protein Binding; Protein Conformation; Protein Structure, Secondary; Pyrazines; Recombinant Proteins; Scyphozoa | 2000 |
Antioxidative properties of natural coelenterazine and synthetic methyl coelenterazine in rat hepatocytes subjected to tert-butyl hydroperoxide-induced oxidative stress.
Topics: Animals; Antioxidants; Dose-Response Relationship, Drug; Drug Interactions; Imidazoles; In Vitro Techniques; Lipid Peroxidation; Liver; Male; Oxidative Stress; Pyrazines; Rats; Rats, Wistar; tert-Butylhydroperoxide | 2000 |
Vascular oxidant stress early after balloon injury: evidence for increased NAD(P)H oxidoreductase activity.
Topics: Acridines; Animals; Biphenyl Compounds; Catheterization; Cyclic N-Oxides; Cyclooxygenase Inhibitors; Electron Spin Resonance Spectroscopy; Electron Transport; Endothelium, Vascular; Free Radicals; Glutathione; Imidazoles; Lipoxygenase Inhibitors; Luminescent Measurements; Male; Metalloporphyrins; NAD; NADH, NADPH Oxidoreductases; NADP; NADPH Oxidases; NF-kappa B; Nitric Oxide Synthase; Onium Compounds; Oxidation-Reduction; Oxidative Stress; Oxygen Consumption; Pyrazines; Rabbits; Reactive Oxygen Species; Recombinant Fusion Proteins; Spin Labels; Superoxide Dismutase; Superoxides; Transcription, Genetic; Wound Healing; Xanthine Oxidase | 2000 |
Secretional luciferase of the luminous shrimp Oplophorus gracilirostris: cDNA cloning of a novel imidazopyrazinone luciferase(1).
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Catalysis; Cloning, Molecular; COS Cells; Decapoda; Escherichia coli; Imidazoles; Leucine; Luciferases; Luminescence; Microsomes; Molecular Sequence Data; Molecular Weight; Protein Biosynthesis; Pyrazines; Recombinant Fusion Proteins; Repetitive Sequences, Amino Acid; Sequence Alignment; Transfection | 2000 |
Fusions to imidazopyrazinone-type luciferases and aequorin as reporters.
Topics: Aequorin; Animals; Artificial Gene Fusion; Cnidaria; Cyprinidae; Decapoda; Firefly Luciferin; Genes, Reporter; Imidazoles; Luciferases; Luminescent Measurements; Pyrazines | 2000 |
Structure of the Ca2+-regulated photoprotein obelin at 1.7 A resolution determined directly from its sulfur substructure.
Topics: Aequorin; Amino Acid Sequence; Calcium; Crystallography, X-Ray; Imidazoles; Luminescent Proteins; Models, Molecular; Molecular Sequence Data; Oxygen; Protein Binding; Protein Conformation; Protein Structure, Secondary; Pyrazines; Recombinant Proteins; Sequence Homology, Amino Acid; Sulfur | 2000 |
Design, synthesis, and evaluation of the transition- state inhibitors of coelenterazine bioluminescence: probing the chiral environment of active site.
Topics: Animals; Binding Sites; Cnidaria; Crystallography, X-Ray; Imidazoles; Kinetics; Luminescent Measurements; Magnetic Resonance Spectroscopy; Models, Chemical; Pyrazines; Stereoisomerism | 2001 |
Imidazolopyrazinones as potential antioxidants.
Topics: Antioxidants; Drug Evaluation, Preclinical; Imidazoles; Magnetic Resonance Spectroscopy; Molecular Structure; Pyrazines; Pyrazoles; Reactive Oxygen Species; Structure-Activity Relationship; Superoxides | 2001 |
Dense core secretory vesicles revealed as a dynamic Ca(2+) store in neuroendocrine cells with a vesicle-associated membrane protein aequorin chimaera.
Topics: Adenosine Triphosphate; Adenoviridae; Aequorin; Animals; Caffeine; Calcium; Cell Line; Central Nervous System Stimulants; Chelating Agents; Egtazic Acid; Endoplasmic Reticulum; Genes, Reporter; Imidazoles; Immunohistochemistry; Inositol 1,4,5-Trisphosphate; Islets of Langerhans; Membrane Proteins; Nerve Tissue Proteins; Pyrazines; R-SNARE Proteins; Recombinant Fusion Proteins; Ryanodine Receptor Calcium Release Channel; Secretory Vesicles | 2001 |
Can coelenterates make coelenterazine? Dietary requirement for luciferin in cnidarian bioluminescence.
Topics: Animals; Artemia; Cnidaria; Diet; Firefly Luciferin; Imidazoles; Kinetics; Luminescent Measurements; Physical Stimulation; Pyrazines; Scyphozoa; Seawater | 2001 |
Isolation and properties of the luciferase stored in the ovary of the scyphozoan medusa Periphylla periphylla.
Topics: Animals; Chromatography, Gel; Chromatography, Ion Exchange; Electrophoresis, Polyacrylamide Gel; Female; Guanidine; Hot Temperature; Hydrogen-Ion Concentration; Imidazoles; Luciferases; Luminescent Measurements; Mercaptoethanol; Molecular Weight; Ovary; Pyrazines; Scyphozoa | 2001 |
Optical imaging of Renilla luciferase reporter gene expression in living mice.
Topics: Animals; Coleoptera; Dose-Response Relationship, Drug; Genes, Reporter; Imidazoles; Kinetics; Light; Luciferases; Luminescent Measurements; Mice; Protein Binding; Pyrazines; Radionuclide Imaging; Rats; Time Factors; Transfection; Tumor Cells, Cultured | 2002 |
Synthesis of 2-amino-3-benzyl-5-(p-hydroxyphenyl)pyrazine.
Topics: Imidazoles; Luminescent Measurements; Molecular Conformation; Pyrazines | 2002 |
Control of oxygen free radical formation from mitochondrial complex I: roles for protein kinase A and pyruvate dehydrogenase kinase.
Topics: Adenosine Triphosphate; Animals; Blotting, Western; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Electron Transport Complex I; Enzyme Activation; Firefly Luciferin; Humans; Imidazoles; Membrane Proteins; Mitochondria, Heart; NAD; NADH Dehydrogenase; NADH, NADPH Oxidoreductases; Oxygen Consumption; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Pyrazines; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxides | 2002 |
Reorientation of seedlings in the earth's gravitational field induces cytosolic calcium transients.
Topics: Adaptation, Physiological; Aequorin; Arabidopsis; Calcium; Cytoplasm; Equipment Design; Gravitropism; Gravity Sensing; Imidazoles; Indoleacetic Acids; Phthalimides; Pyrazines; Stress, Mechanical; Triiodobenzoic Acids | 2002 |
Bioluminescence reaction catalyzed by membrane-bound luciferase in the "firefly squid," Watasenia scintillans.
Topics: Adenosine Triphosphate; Animals; Decapodiformes; Diphosphates; Enzyme Activation; Female; Firefly Luciferin; Imidazoles; Luciferases; Luminescent Measurements; Models, Chemical; Organ Specificity; Oxygen; Pyrazines | 2002 |
Protection of peroxide-treated fish erythrocytes by coelenterazine and coelenteramine.
Topics: Animals; Bass; Chromans; Comet Assay; DNA Damage; Dose-Response Relationship, Drug; Erythrocytes; Glutathione; Hemolysis; Imidazoles; Lipid Peroxidation; Oxidative Stress; Pyrazines; tert-Butylhydroperoxide; Thiobarbituric Acid Reactive Substances | 2002 |
Protective effect of imidazolopyrazinone antioxidants on ischemia/reperfusion injury.
Topics: Amidines; Animals; Antioxidants; Capillary Permeability; Cricetinae; Firefly Luciferin; Imidazoles; Lipid Peroxidation; Microcirculation; Protective Agents; Pyrazines; Reperfusion Injury; Structure-Activity Relationship | 2003 |
Synthesis, structure-activity relationship and in vitro evaluation of coelenterazine and coelenteramine derivatives as inhibitors of lipid peroxidation.
Topics: Antioxidants; Imidazoles; Linoleic Acid; Lipid Peroxidation; Micelles; Models, Chemical; Oxygen; Pyrazines; Structure-Activity Relationship; Time Factors | 2003 |
Activation of NAD(P)H oxidase by lipid hydroperoxides: mechanism of oxidant-mediated smooth muscle cytotoxicity.
Topics: Animals; Arteriosclerosis; Cell Survival; Cells, Cultured; Enzyme Activation; Free Radicals; Imidazoles; Linoleic Acids; Lipid Peroxides; Male; Membrane Transport Proteins; Microscopy, Confocal; Muscle, Smooth; NADPH Dehydrogenase; NADPH Oxidases; Oligonucleotides, Antisense; Oxidants; Oxidative Stress; Oxygen; Phosphoproteins; Pyrazines; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Superoxides; Transfection | 2003 |
Violet bioluminescence and fast kinetics from W92F obelin: structure-based proposals for the bioluminescence triggering and the identification of the emitting species.
Topics: Animals; Binding Sites; Calcium; Color; Crystallography, X-Ray; Hydrozoa; Imidazoles; In Vitro Techniques; Kinetics; Luminescent Measurements; Luminescent Proteins; Magnesium; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Protons; Pyrazines; Spectrophotometry | 2003 |
A functional assay for G-protein-coupled receptors using stably transformed insect tissue culture cell lines.
Topics: Aequorin; Animals; Biological Assay; Cattle; Cell Line, Transformed; Dopamine Agonists; Dose-Response Relationship, Drug; GTP-Binding Protein alpha Subunits, Gq-G11; Heterotrimeric GTP-Binding Proteins; Humans; Imidazoles; Ligands; Moths; Pyrazines; Receptors, Dopamine D1; Receptors, G-Protein-Coupled | 2003 |
Atomic resolution structure of obelin: soaking with calcium enhances electron density of the second oxygen atom substituted at the C2-position of coelenterazine.
Topics: Binding Sites; Calcium; Carbon; Crystallography; Electrons; Imidazoles; Luminescent Proteins; Macromolecular Substances; Nanotechnology; Oxygen; Protein Binding; Protein Conformation; Protein Subunits; Pyrazines; Solutions | 2003 |
Lucigenin and coelenterazine as superoxide probes in mitochondrial and bacterial membranes.
Topics: Acridines; Animals; Cell Membrane; Firefly Luciferin; Hypoxanthine; Imidazoles; Intracellular Membranes; Luminescent Measurements; Mitochondria, Liver; Molecular Probes; NADH, NADPH Oxidoreductases; Oxidation-Reduction; Paracoccus denitrificans; Pyrazines; Rats; Superoxides; Time Factors; Xanthine Oxidase | 2004 |
Imaging reversal of multidrug resistance in living mice with bioluminescence: MDR1 P-glycoprotein transports coelenterazine.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Drug Resistance, Multiple; Imidazoles; Luminescent Measurements; Mice; Pyrazines; Transfection | 2004 |
Coelenterazine: a two-stage antioxidant in lipid micelles.
Topics: Amidines; Antioxidants; Free Radicals; Imidazoles; Linoleic Acid; Lipid Metabolism; Lipid Peroxidation; Micelles; Molecular Structure; Nitriles; Oxidation-Reduction; Pyrazines; Structure-Activity Relationship; Time Factors | 2004 |
Characterization of coelenterazine analogs for measurements of Renilla luciferase activity in live cells and living animals.
Topics: Animals; Anthozoa; Cell Line, Tumor; Dose-Response Relationship, Drug; Genes, Reporter; Glioma; HeLa Cells; Humans; Imidazoles; Injections, Intravenous; Kinetics; Luciferases; Luminescent Measurements; Male; Mice; Mice, Inbred Strains; Molecular Structure; Protein Binding; Pyrazines; Radionuclide Imaging; Rats; Substrate Specificity; Time Factors; Transfection | 2004 |
Identification of the luciferin-luciferase system and quantification of coelenterazine by mass spectrometry in the deep-sea luminous ostracod Conchoecia pseudodiscophora.
Topics: Animals; Crustacea; Firefly Luciferin; Imidazoles; Luciferases; Luminescent Measurements; Mass Spectrometry; Molecular Structure; Pyrazines; Species Specificity; Time Factors | 2004 |
Blue fluorescent protein from the calcium-sensitive photoprotein aequorin is a heat resistant enzyme, catalyzing the oxidation of coelenterazine.
Topics: Aequorin; Calcium; Catalysis; Circular Dichroism; Hot Temperature; Imidazoles; Indicators and Reagents; Luminescent Proteins; Oxidation-Reduction; Pyrazines; Spectrometry, Fluorescence; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2004 |
Monitoring dynamic expression of nuclear genes in Chlamydomonas reinhardtii by using a synthetic luciferase reporter gene.
Topics: Algal Proteins; Animals; Chlamydomonas reinhardtii; Enzyme Stability; Escherichia coli; Gene Expression; Imidazoles; Luciferases; Nuclear Proteins; Photosynthetic Reaction Center Complex Proteins; Plasmids; Promoter Regions, Genetic; Pyrazines; Recombinant Fusion Proteins; Ribulose-Bisphosphate Carboxylase; Substrate Specificity; Time Factors; Transfection | 2004 |
The crystal structures of semi-synthetic aequorins.
Topics: Aequorin; Animals; Calcium; Crystallography, X-Ray; Electrons; Hydrozoa; Imidazoles; Luminescent Proteins; Models, Chemical; Models, Molecular; Peroxides; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Pyrazines; Recombinant Proteins | 2005 |
Chimeric G proteins extend the range of insect cell-based functional assays for human G protein-coupled receptors.
Topics: Animals; Biochemistry; Cell Culture Techniques; Cell Line; Culture Media, Serum-Free; DNA, Complementary; Dose-Response Relationship, Drug; Genes, Reporter; Humans; Imidazoles; Insecta; Pyrazines; Receptors, G-Protein-Coupled; Recombinant Fusion Proteins; Signal Transduction; Transfection; Type C Phospholipases | 2004 |
Oxidized LDL induces mitochondrially associated reactive oxygen/nitrogen species formation in endothelial cells.
Topics: Animals; Aorta; Butanones; Cattle; Cells, Cultured; Electron Transport Chain Complex Proteins; Endothelial Cells; Enzyme Inhibitors; Esterases; Fluoresceins; Humans; Imidazoles; Lipoproteins, LDL; Mitochondria; Nitric Oxide Synthase; Pyrazines; Reactive Nitrogen Species; Reactive Oxygen Species; Rotenone; Thenoyltrifluoroacetone; Thiophenes | 2005 |
Extended bioluminescence resonance energy transfer (eBRET) for monitoring prolonged protein-protein interactions in live cells.
Topics: Animals; Cell Survival; Cells, Cultured; Chlorocebus aethiops; COS Cells; Energy Transfer; Humans; Imidazoles; Kinetics; Luciferases, Renilla; Protein Binding; Proteins; Pyrazines; Recombinant Fusion Proteins; Reproducibility of Results; Spectrometry, Fluorescence; Substrate Specificity | 2006 |
Self-illuminating quantum dots light the way.
Topics: Energy Transfer; Fluorescence; Imidazoles; Luciferases; Luminescent Agents; Luminescent Measurements; Models, Biological; Nanotechnology; Protein Binding; Pyrazines; Quantum Dots; Semiconductors; Substrate Specificity | 2006 |
Blue fluorescent protein from the calcium-sensitive photoprotein aequorin: catalytic properties for the oxidation of coelenterazine as an oxygenase.
Topics: Aequorin; Animals; Calcium; Catalysis; Imidazoles; Luciferases; Luminescent Measurements; Luminescent Proteins; Oxidation-Reduction; Oxygenases; Pyrazines; Recombinant Proteins; Spectrometry, Fluorescence; Substrate Specificity | 2006 |
Transient expression of apoaequorin in zebrafish embryos: extending the ability to image calcium transients during later stages of development.
Topics: Aequorin; Animals; Apoproteins; Calcium Signaling; Imidazoles; Microscopy, Fluorescence; Pyrazines; Recombinant Proteins; Transfection; Zebrafish | 2006 |
Imidazole-assisted catalysis of luminescence reaction in blue fluorescent protein from the photoprotein aequorin.
Topics: Aequorin; Amides; Binding Sites; Calcium; Catalysis; Imidazoles; Kinetics; Luciferases; Luminescent Agents; Luminescent Proteins; Osmolar Concentration; Oxidation-Reduction; Oxygen; Protons; Pyrazines; Spectrometry, Fluorescence | 2007 |
Creating self-illuminating quantum dot conjugates.
Topics: Energy Transfer; Imidazoles; Luciferases, Renilla; Luminescence; Nanotechnology; Pyrazines; Quantum Dots | 2006 |
Development of a Ca(2+)-activated photoprotein, Photina, and its application to high-throughput screening.
Topics: Adenosine Triphosphate; Aequorin; Amino Acid Sequence; Animals; Calcium; Cell Survival; Chemokine CX3CL1; CHO Cells; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Histamine; Imidazoles; Inhibitory Concentration 50; Luminescent Measurements; Luminescent Proteins; Mitochondria; Molecular Sequence Data; Protein Engineering; Pyrazines; Receptors, G-Protein-Coupled; Receptors, Purinergic; Recombinant Proteins; Reproducibility of Results; Transfection | 2007 |
Aequorin luminescence-based assay for 5-hydroxytryptamine (serotonin) type 3 receptor characterization.
Topics: Aequorin; Calcium; Cells, Cultured; Humans; Imidazoles; Ligands; Luminescent Agents; Luminescent Measurements; Pyrazines; Receptors, Serotonin, 5-HT3; Reproducibility of Results; Sensitivity and Specificity; Transfection | 2007 |
Crystal structures of the luciferase and green fluorescent protein from Renilla reniformis.
Topics: Animals; Crystallization; Green Fluorescent Proteins; Hydrozoa; Imidazoles; Luciferases; Models, Molecular; Protein Conformation; Pyrazines; Renilla | 2007 |
Coelenterazine-binding protein of Renilla muelleri: cDNA cloning, overexpression, and characterization as a substrate of luciferase.
Topics: Amino Acid Sequence; Animals; Anthozoa; Base Sequence; Cloning, Molecular; DNA Primers; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Imidazoles; Luciferases; Molecular Sequence Data; Proteins; Pyrazines; Sequence Homology, Amino Acid; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Substrate Specificity | 2008 |
Bioluminescence of the arm light organs of the luminous squid Watasenia scintillans.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animal Structures; Animals; Catalysis; Decapodiformes; Enzyme Stability; Hydrogen-Ion Concentration; Imidazoles; Kinetics; Luciferases; Luminescence; Luminescent Measurements; Magnesium Chloride; Molecular Structure; Particle Size; Photochemistry; Pyrazines; Spectrophotometry; Subcellular Fractions; Sucrose; Temperature | 2008 |
Structure-function studies on the active site of the coelenterazine-dependent luciferase from Renilla.
Topics: Aequorin; Amino Acid Sequence; Binding Sites; Catalysis; Computer Simulation; Diethyl Pyrocarbonate; Imidazoles; Isoxazoles; Luciferases, Renilla; Luminescent Measurements; Models, Molecular; Mutagenesis, Site-Directed; Phenylmethylsulfonyl Fluoride; Pyrazines; Structure-Activity Relationship | 2008 |
A bioluminescent molecular switch for glucose.
Topics: Aequorin; Biosensing Techniques; Carrier Proteins; Glucose; Imidazoles; Luminescence; Luminescent Measurements; Nanotechnology; Protein Conformation; Pyrazines; Recombinant Fusion Proteins | 2008 |
Crystal structure of coelenterazine-binding protein from Renilla muelleri at 1.7 A: why it is not a calcium-regulated photoprotein.
Topics: Amino Acid Sequence; Animals; Calcium; Crystallography, X-Ray; Imidazoles; Luminescent Proteins; Models, Molecular; Molecular Sequence Data; Protein Binding; Protein Structure, Tertiary; Pyrazines; Renilla; Sequence Alignment | 2008 |
Rapid, single-step nucleic acid detection.
Topics: DNA; Energy Transfer; Escherichia coli; Imidazoles; Luciferases, Renilla; Luminescent Agents; Luminescent Measurements; Nucleic Acid Hybridization; Oligonucleotide Probes; Pyrazines; Quantum Dots | 2008 |
Structure based mechanism of the Ca(2+)-induced release of coelenterazine from the Renilla binding protein.
Topics: Amino Acid Sequence; Animals; Binding Sites; Calcium; Calcium-Binding Proteins; Crystallography, X-Ray; Imidazoles; Luciferases, Renilla; Luminescent Agents; Models, Molecular; Molecular Sequence Data; Protein Conformation; Pyrazines; Renilla; Spectrometry, Fluorescence; Structure-Activity Relationship; Substrate Specificity | 2009 |
Calcium-sensitive photoproteins.
Topics: Aequorin; Algorithms; Calcium; Cytosol; Imidazoles; Luminescent Proteins; Pyrazines; Recombinant Fusion Proteins; Subcellular Fractions; Transfection | 2008 |
Genetically modified semisynthetic bioluminescent photoprotein variants: simultaneous dual-analyte assay in a single well employing time resolution of decay kinetics.
Topics: 6-Ketoprostaglandin F1 alpha; Aequorin; Angiotensin II; Animals; Escherichia coli; Half-Life; Imidazoles; Immunoassay; Kinetics; Mutation; Protein Engineering; Pyrazines | 2008 |
Development of an aequorin luminescence calcium assay for high-throughput screening using a plate reader, the LumiLux.
Topics: Aequorin; Aniline Compounds; Animals; Apoproteins; Calcium; CHO Cells; Cluster Analysis; Cricetinae; Cricetulus; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; False Positive Reactions; Fluorescence; Fluorescent Dyes; Imidazoles; Inhibitory Concentration 50; Kinetics; Luminescent Agents; Luminescent Measurements; Pyrazines; Receptors, Calcium-Sensing; Receptors, Dopamine; Robotics; Software; Xanthenes | 2008 |
Aequorin variants with improved bioluminescence properties.
Topics: Aequorin; Apoproteins; Bacillus; Escherichia coli; Imidazoles; Luminescent Agents; Luminescent Proteins; Mutagenesis, Site-Directed; Mutation; Oxygen; Protein Stability; Pyrazines; Recombinant Proteins | 2009 |
The intrinsic fluorescence of apo-obelin and apo-aequorin and use of its quenching to characterize coelenterazine binding.
Topics: Aequorin; Amino Acid Sequence; Amino Acid Substitution; Animals; Apoproteins; Fluorescence; Hydrozoa; Imidazoles; Kinetics; Luminescent Proteins; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Binding; Pyrazines; Recombinant Proteins; Sequence Homology, Amino Acid; Spectrometry, Fluorescence; Tryptophan | 2009 |
Discovery of green fluorescent protein (GFP) (Nobel Lecture).
Topics: Aequorin; Biochemistry; Calcium; Firefly Luciferin; Fluorescent Dyes; Green Fluorescent Proteins; History, 20th Century; Imidazoles; Japan; Nobel Prize; Pyrazines | 2009 |
Bioluminescent CXCL12 fusion protein for cellular studies of CXCR4 and CXCR7.
Topics: Animals; Biological Assay; Breast Neoplasms; Cell Line; Cell Line, Tumor; Chemokine CXCL12; Copepoda; Drug Discovery; Female; Genetic Vectors; Green Fluorescent Proteins; Humans; Imidazoles; Kidney; Lentivirus; Luciferases; Luminescent Measurements; Luminescent Proteins; Promoter Regions, Genetic; Protein Binding; Pyrazines; Receptors, CXCR; Receptors, CXCR4; Recombinant Fusion Proteins; Signal Transduction; Substrate Specificity; Transduction, Genetic | 2009 |
Regio- and chemoselective multiple functionalization of chloropyrazine derivatives. Application to the synthesis of coelenterazine.
Topics: Animals; Imidazoles; Organometallic Compounds; Pyrazines; Pyruvaldehyde; Scyphozoa | 2009 |
Biosynthesis of coelenterazine in the deep-sea copepod, Metridia pacifica.
Topics: Animals; Copepoda; Imidazoles; Luminescent Agents; Phenylalanine; Pyrazines; Tyrosine | 2009 |
Theoretical investigation of thermal decomposition of peroxidized coelenterazines with and without external perturbations.
Topics: Aequorin; Binding Sites; Electrons; Hydrogen Bonding; Imidazoles; Models, Molecular; Molecular Conformation; Peroxides; Protons; Pyrazines; Quantum Theory; Temperature; Thermodynamics | 2009 |
Modulating the bioluminescence emission of photoproteins by in vivo site-directed incorporation of non-natural amino acids.
Topics: Aequorin; Amino Acid Substitution; Amino Acids; Escherichia coli; Imidazoles; Luminescent Measurements; Luminescent Proteins; Mutagenesis, Site-Directed; Pyrazines; Tyrosine | 2010 |
Optimization of enzyme-substrate pairing for bioluminescence imaging of gene transfer using Renilla and Gaussia luciferases.
Topics: Animals; Cell Line; Copepoda; Gene Transfer Techniques; Genes, Reporter; Humans; Imidazoles; Luciferases; Luminescent Agents; Luminescent Measurements; Luminescent Proteins; Male; Mice; Mice, Nude; Pyrazines; Renilla | 2010 |
Coelenterazine-v ligated to Ca2+-triggered coelenterazine-binding protein is a stable and efficient substrate of the red-shifted mutant of Renilla muelleri luciferase.
Topics: Animals; Calcium; Calcium-Binding Proteins; Imidazoles; Luciferases; Luminescent Agents; Mutation; Protein Binding; Pyrazines; Renilla; Substrate Specificity | 2010 |
Application of new semisynthetic aequorins with long half-decay time of luminescence to G-protein-coupled receptor assay.
Topics: Aequorin; Animals; Apoproteins; Calcium; CHO Cells; Cricetinae; Cricetulus; Half-Life; Imidazoles; Kinetics; Luminescent Agents; Oxygen; Pyrazines; Receptors, G-Protein-Coupled; Receptors, Muscarinic; Recombinant Proteins; Spectrometry, Fluorescence | 2010 |
A coelenterazine-based luminescence assay to quantify high-molecular-weight superoxide anion scavenger activities.
Topics: Antioxidants; Biological Assay; Free Radical Scavengers; Imidazoles; Luminescence; Luminescent Measurements; Oxidation-Reduction; Pyrazines; Reactive Oxygen Species; Superoxide Dismutase; Superoxides | 2010 |
The use of aequorins to record and visualize Ca(2+) dynamics: from subcellular microdomains to whole organisms.
Topics: Aequorin; Animals; Apoproteins; Calcium; Calcium Signaling; Cell Line; Green Fluorescent Proteins; Imidazoles; Luminescent Measurements; Mice; Pyrazines; Recombinant Fusion Proteins; Recombinant Proteins; Subcellular Fractions; Transfection; Zebrafish | 2010 |
Evaluation of the reversal of multidrug resistance by MDR1 ribonucleic acid interference in a human colon cancer model using a Renilla luciferase reporter gene and coelenterazine.
Topics: Adenoviridae; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Colonic Neoplasms; Cyclosporine; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Genes, Reporter; Humans; Imidazoles; Immunohistochemistry; Luciferases, Renilla; Luminescent Measurements; Mice; Models, Biological; Pyrazines; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Small Interfering | 2010 |
Video rate bioluminescence imaging of secretory proteins in living cells: localization, secretory frequency, and quantification.
Topics: Animals; Copepoda; Glucose; Glyburide; Imidazoles; Insulin; Insulin Secretion; Insulin-Secreting Cells; Luciferases; Luminescent Measurements; Mice; Protein Precursors; Pyrazines; Recombinant Fusion Proteins; Video Recording | 2011 |
ATP-binding cassette transporters modulate both coelenterazine- and D-luciferin-based bioluminescence imaging.
Topics: Animals; ATP-Binding Cassette Transporters; Benzothiazoles; Female; Genes, Reporter; HEK293 Cells; Humans; Imaging, Three-Dimensional; Imidazoles; Luminescent Measurements; Mice; Mice, Nude; NIH 3T3 Cells; Pyrazines; Time Factors; Transplantation, Heterologous | 2011 |
Gaussia luciferase for bioluminescence tumor monitoring in comparison with firefly luciferase.
Topics: Animals; Area Under Curve; Genes, Reporter; HCT116 Cells; Humans; Imidazoles; Kinetics; Luciferases; Mice; Mice, SCID; Neoplasms, Experimental; Pyrazines; Spectrometry, Fluorescence; Statistics, Nonparametric; Whole Body Imaging | 2011 |
Bioluminescence resonance energy transfer (BRET) imaging of protein-protein interactions within deep tissues of living subjects.
Topics: Animals; Blotting, Western; Drug Evaluation, Preclinical; Fluorescence Resonance Energy Transfer; Imidazoles; Luciferases, Renilla; Luminescent Proteins; Mice; Plasmids; Protein Binding; Pyrazines; Red Fluorescent Protein; Tacrolimus Binding Protein 1A; TOR Serine-Threonine Kinases | 2011 |
A unique EF-hand motif in mnemiopsin photoprotein from Mnemiopsis leidyi: implication for its low calcium sensitivity.
Topics: Aequorin; Amino Acid Sequence; Animals; Calcium; Ctenophora; Hydrogen-Ion Concentration; Imidazoles; Luminescent Proteins; Molecular Sequence Data; Protein Conformation; Pyrazines | 2011 |
Ca(2+)-triggered coelenterazine-binding protein from Renilla as an enzyme-dependent label for binding assay.
Topics: Animals; Calcium; Imidazoles; Luciferases, Renilla; Luminescent Agents; Luminescent Measurements; Models, Molecular; Protein Binding; Proteins; Pyrazines; Renilla | 2011 |
Enhanced Gaussia luciferase blood assay for monitoring of in vivo biological processes.
Topics: Animals; Copepoda; Genes, Reporter; Glioma; Humans; Imidazoles; Luciferases; Luminescent Measurements; Mice; Mice, Nude; Pyrazines; Tumor Cells, Cultured | 2012 |
A water-soluble coelenterazine for sensitive in vivo imaging of coelenterate luciferases.
Topics: Animals; Imidazoles; Luciferases; Luminescent Measurements; Pyrazines; Solubility; Water | 2012 |
Stem cell-based photodynamic therapy.
Topics: Aminolevulinic Acid; Animals; Cell Line, Tumor; Cell Survival; Female; Fetal Blood; Imidazoles; Luciferases; Lung Neoplasms; Melanoma; Mice; Mice, Inbred C57BL; Neural Stem Cells; Oxidation-Reduction; Photochemotherapy; Photosensitizing Agents; Plasmids; Protoporphyrins; Pyrazines; Rats; Stem Cell Transplantation; Stem Cells; Transfection | 2012 |
Ultrasensitive detection of cellular protein interactions using bioluminescence resonance energy transfer quantum dot-based nanoprobes.
Topics: 3T3 Cells; Animals; Bioluminescence Resonance Energy Transfer Techniques; Chlorocebus aethiops; COS Cells; Humans; Imidazoles; Luciferases, Renilla; Membrane Proteins; Mice; Nanoparticles; Protein Interaction Mapping; Pyrazines; Quantum Dots; Receptors, Fc; Streptavidin | 2012 |
Substrate cooperativity in marine luciferases.
Topics: Amino Acid Sequence; Animals; Aquatic Organisms; Benzothiazoles; Copepoda; Imidazoles; Luciferases; Molecular Sequence Data; Pyrazines; Sequence Alignment; Substrate Specificity | 2012 |
Discovery and validation of small-molecule heat-shock protein 90 inhibitors through multimodality molecular imaging in living subjects.
Topics: Acetamides; Animals; Benzoquinones; Blotting, Western; Cell Line, Tumor; Drug Discovery; High-Throughput Screening Assays; HSP90 Heat-Shock Proteins; Humans; Imidazoles; Immunoprecipitation; Intramolecular Oxidoreductases; Lactams, Macrocyclic; Lead; Luciferases, Firefly; Luciferases, Renilla; Mice; Mice, Nude; Neoplasms; Positron-Emission Tomography; Prostaglandin-E Synthases; Protein Folding; Protein Isoforms; Pyrazines; Small Molecule Libraries; Thioacetamide; Thiophenes; Tomography, X-Ray Computed; Tritium | 2012 |
Bioluminescence inhibition assay for the detection of hydroxylated polychlorinated biphenyls.
Topics: Aequorin; Dimethyl Sulfoxide; Endocrine Disruptors; Environmental Pollutants; Humans; Hydroxylation; Imidazoles; Luminescent Measurements; Polychlorinated Biphenyls; Pyrazines; Recombinant Proteins | 2012 |
Ligand binding and conformational states of the photoprotein obelin.
Topics: Calcium; Circular Dichroism; Imidazoles; Luminescent Proteins; Protein Binding; Protein Folding; Pyrazines; Spectrometry, Fluorescence | 2012 |
Bioluminescence resonance energy transfer coupled near-infrared quantum dots using GST-tagged luciferase for in vivo imaging.
Topics: Animals; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Glutathione Transferase; Imidazoles; Luciferases; Luminescent Measurements; Lymph Nodes; Mice; Pyrazines; Quantum Dots; Recombinant Fusion Proteins; Whole Body Imaging | 2013 |
Application of quantum dot nanoparticles for potential non-invasive bio-imaging of mammalian spermatozoa.
Topics: Animals; Cell Survival; Fluorescent Dyes; Imidazoles; Luciferases; Male; Microscopy, Confocal; Pyrazines; Quantum Dots; Spermatozoa; Sus scrofa | 2012 |
Expression and characterization of the calcium-activated photoprotein from the ctenophore Bathocyroe fosteri: insights into light-sensitive photoproteins.
Topics: Amino Acid Sequence; Animals; Calcium; Calcium-Binding Proteins; Cloning, Molecular; Ctenophora; Imidazoles; Luminescence; Luminescent Agents; Luminescent Proteins; Molecular Sequence Data; Phylogeny; Protein Conformation; Pyrazines | 2013 |
Expression, purification and luminescence properties of coelenterazine-utilizing luciferases from Renilla, Oplophorus and Gaussia: comparison of substrate specificity for C2-modified coelenterazines.
Topics: Animals; Catalysis; Copepoda; Escherichia coli; Imidazoles; Luciferases, Renilla; Luminescent Measurements; Pyrazines; Renilla; Substrate Specificity | 2013 |
Oxygen activation of apo-obelin-coelenterazine complex.
Topics: Animals; Calcium; Histidine; Hydrozoa; Imidazoles; Luminescence; Luminescent Proteins; Models, Molecular; Oxygen; Protein Binding; Protons; Pyrazines; Spectrophotometry | 2013 |
Reconstitution of holo-aequorin with apoaequorin mRNA and coelenterazine in zebrafish embryos.
Topics: Aequorin; Animals; Apoproteins; Embryo, Nonmammalian; Gene Expression; Imidazoles; Microinjections; Pyrazines; Recombinant Proteins; RNA, Messenger; Zebrafish | 2013 |
C6-Deoxy coelenterazine analogues as an efficient substrate for glow luminescence reaction of nanoKAZ: the mutated catalytic 19 kDa component of Oplophorus luciferase.
Topics: Amino Acid Sequence; Animals; Catalytic Domain; CHO Cells; Copepoda; Cricetinae; Cricetulus; Decapoda; Escherichia coli; Imidazoles; Luciferases; Luminescence; Molecular Sequence Data; Mutant Proteins; Protein Sorting Signals; Pyrazines; Recombinant Fusion Proteins; Substrate Specificity | 2013 |
Spatial structure of the novel light-sensitive photoprotein berovin from the ctenophore Beroe abyssicola in the Ca(2+)-loaded apoprotein conformation state.
Topics: Amino Acid Sequence; Amino Acids; Animals; Apoproteins; Calcium; Crystallography, X-Ray; Ctenophora; Escherichia coli; Hydrogen-Ion Concentration; Imidazoles; Light; Luminescent Measurements; Luminescent Proteins; Models, Molecular; Molecular Sequence Data; Oxygen; Protein Conformation; Protein Structure, Tertiary; Pyrazines; Recombinant Proteins; Sequence Alignment | 2013 |
Role of key residues of obelin in coelenterazine binding and conversion into 2-hydroperoxy adduct.
Topics: Amino Acid Substitution; Apoproteins; Calcium; Imidazoles; Kinetics; Luminescent Proteins; Models, Molecular; Mutation; Protein Binding; Protein Conformation; Pyrazines; Spectrometry, Fluorescence | 2013 |
Development of luminescent coelenterazine derivatives activatable by β-galactosidase for monitoring dual gene expression.
Topics: Animals; beta-Galactosidase; Biosensing Techniques; Cell Line, Tumor; Galactose; Gene Expression; Humans; Imidazoles; Luciferases; Luminescence; Luminescent Measurements; Pyrazines; Substrate Specificity | 2013 |
Subcellular calcium measurements in mammalian cells using jellyfish photoprotein aequorin-based probes.
Topics: Aequorin; Animals; Calcium; Cell Culture Techniques; Imidazoles; Luminescent Measurements; Luminescent Proteins; Mammals; Oxidation-Reduction; Pyrazines; Scyphozoa; Transfection | 2013 |
A Novel Catalytic Function of Synthetic IgG-Binding Domain (Z Domain) from Staphylococcal Protein A: Light Emission with Coelenterazine.
Topics: Animals; Catalysis; Electrophoresis, Polyacrylamide Gel; Imidazoles; Immunoglobulin G; Luciferases; Luminescence; Protein Binding; Protein Domains; Pyrazines; Staphylococcal Protein A | 2014 |
Using targeted variants of aequorin to measure Ca2+ levels in intracellular organelles.
Topics: Aequorin; Animals; Calcium; Gene Expression; Hydrozoa; Imidazoles; Organelles; Photons; Protein Binding; Protein Transport; Pyrazines; Recombinant Proteins | 2014 |
NanoLuc reporter for dual luciferase imaging in living animals.
Topics: Animals; Breast Neoplasms; Cell Line; Disease Progression; Female; Heterografts; Imidazoles; Luciferases; Luciferases, Firefly; Luminescent Measurements; Mice; Molecular Imaging; Neoplasm Transplantation; Pyrazines; Signal Transduction; Substrate Specificity; Transfection; Transforming Growth Factor beta | 2013 |
Hydrogen-bond networks between the C-terminus and Arg from the first α-helix stabilize photoprotein molecules.
Topics: Aequorin; Arginine; Crystallization; Escherichia coli; Hydrogen Bonding; Imidazoles; Kinetics; Luminescent Measurements; Luminescent Proteins; Mutation; Proline; Protein Stability; Protein Structure, Secondary; Pyrazines; Recombinant Proteins | 2014 |
Luminescence enhancement of the catalytic 19 kDa protein (KAZ) of Oplophorus luciferase by three amino acid substitutions.
Topics: Amino Acid Substitution; Animals; Biocatalysis; CHO Cells; Cricetinae; Cricetulus; Decapoda; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Imidazoles; Luciferases; Luminescence; Luminescent Measurements; Molecular Structure; Molecular Weight; Mutagenesis, Site-Directed; Mutant Proteins; Pyrazines; Recombinant Proteins; Substrate Specificity | 2014 |
Bioluminescent properties of obelin and aequorin with novel coelenterazine analogues.
Topics: Aequorin; Animals; CHO Cells; Cricetulus; Hydrozoa; Imidazoles; Luminescent Agents; Luminescent Measurements; Luminescent Proteins; Molecular Imaging; Pyrazines | 2014 |
Bioluminescent coelenterazine derivatives with imidazopyrazinone C-6 extended substitution.
Topics: Animals; Imidazoles; Luciferases, Renilla; Luminescent Agents; Luminescent Measurements; Pyrazines; Renilla; Substrate Specificity | 2015 |
Occurrence of Isopenicillin-N-Synthase Homologs in Bioluminescent Ctenophores and Implications for Coelenterazine Biosynthesis.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Conserved Sequence; Ctenophora; Imidazoles; Luminescence; Luminescent Agents; Luminescent Proteins; Molecular Sequence Data; Nonheme Iron Proteins; Oxidoreductases; Phylogeny; Pyrazines; Sequence Homology, Amino Acid; Species Specificity; Transcriptome | 2015 |
Concise Synthesis of v-Coelenterazines.
Topics: Imidazoles; Luminescence; Luminescent Agents; Marine Biology; Molecular Structure; Pyrazines | 2015 |
Adaptation of a Gaussia princeps Luciferase reporter system in Candida albicans for in vivo detection in the Galleria mellonella infection model.
Topics: Adaptation, Physiological; Animals; Candida albicans; Candidiasis; Copepoda; Disease Models, Animal; Fluconazole; Imidazoles; Larva; Lepidoptera; Luciferases; Luminescent Measurements; Moths; Pyrazines; Virulence | 2015 |
Fiat Luc: Bioluminescence Imaging Reveals In Vivo Viral Replication Dynamics.
Topics: Animals; Arthropod Proteins; Humans; Imidazoles; Luciferases; Luminescent Agents; Luminescent Measurements; Protein Engineering; Pyrazines; Recombinant Proteins; Tissue Distribution; Virus Diseases; Virus Replication; Whole Body Imaging | 2015 |
A new low-Ca²⁺ affinity GAP indicator to monitor high Ca²⁺ in organelles by luminescence.
Topics: Aequorin; Apoproteins; Calcium; Golgi Apparatus; Green Fluorescent Proteins; Humans; Imidazoles; Luminescence; Luminescent Agents; Organelles; Pyrazines; Recombinant Proteins | 2015 |
Multimodality Imaging of Cancer Superoxide Anion Using the Small Molecule Coelenterazine.
Topics: Animals; Female; Flow Cytometry; HeLa Cells; Humans; Imidazoles; Mice, Inbred BALB C; Microscopy, Fluorescence; Multimodal Imaging; Neoplasms; Pyrazines; Small Molecule Libraries; Superoxides | 2016 |
Semisynthetic photoprotein reporters for tracking fast Ca(2+) transients.
Topics: Aequorin; Animals; Calcium; Calcium Signaling; Cations, Divalent; Hydrozoa; Imidazoles; Luminescent Agents; Luminescent Measurements; Luminescent Proteins; Pyrazines | 2015 |
Crystal structure of nanoKAZ: The mutated 19 kDa component of Oplophorus luciferase catalyzing the bioluminescent reaction with coelenterazine.
Topics: Amino Acid Sequence; Animals; Arthropod Proteins; Binding Sites; Catalysis; Computer Simulation; Crustacea; Imidazoles; Luciferases; Luminescent Measurements; Luminescent Proteins; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutation; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Pyrazines | 2016 |
Chemiluminescence Imaging of Superoxide Anion Detects Beta-Cell Function and Mass.
Topics: Animals; Cell Respiration; Diabetes Mellitus, Experimental; Disease Models, Animal; Glucose; HeLa Cells; Humans; Hyperglycemia; Imaging, Three-Dimensional; Imidazoles; Insulin-Secreting Cells; Luminescent Measurements; Mice, Inbred NOD; Organ Size; Pyrazines; Pyridines; Ranolazine; Superoxides | 2016 |
Transient-state kinetic analysis of complex formation between photoprotein clytin and GFP from jellyfish Clytia gregaria.
Topics: Algorithms; Animals; Apoproteins; Benzeneacetamides; Bioluminescence Resonance Energy Transfer Techniques; Calcium Signaling; Dimerization; Fluorescence Resonance Energy Transfer; Green Fluorescent Proteins; Hydrozoa; Imidazoles; Kinetics; Luminescent Proteins; Models, Molecular; Protein Conformation; Protein Interaction Domains and Motifs; Protein Multimerization; Pyrazines; Recombinant Proteins | 2016 |
Reactive Oxygen Species Imaging in a Mouse Model of Inflammatory Bowel Disease.
Topics: Animals; Disease Models, Animal; Imaging, Three-Dimensional; Imidazoles; Inflammatory Bowel Diseases; Luminescent Measurements; Male; Mice; Mice, Inbred BALB C; Pyrazines; RAW 264.7 Cells; Reactive Oxygen Species | 2016 |
Role of certain amino acid residues of the coelenterazine-binding cavity in bioluminescence of light-sensitive Ca(2+)-regulated photoprotein berovin.
Topics: Amino Acids; Animals; Benzeneacetamides; Binding Sites; Calcium; Hydrozoa; Imidazoles; Luminescence; Luminescent Agents; Luminescent Measurements; Luminescent Proteins; Models, Molecular; Protein Binding; Protein Conformation; Pyrazines | 2016 |
Novel bioluminescent coelenterazine derivatives with imidazopyrazinone C-6 extended substitution for Renilla luciferase.
Topics: Cell Line, Tumor; Click Chemistry; Humans; Imidazoles; Luciferases, Renilla; Luminescent Measurements; Pyrazines; Pyrazoles | 2016 |
Imaging Tumor Vascularity and Response to Anti-Angiogenic Therapy Using Gaussia Luciferase.
Topics: Angiogenesis Inhibitors; Animals; Cell Line, Tumor; Copepoda; Humans; Imidazoles; Luciferases; Luminescent Agents; Luminescent Measurements; Neoplasm Transplantation; Neoplasms; Phenylurea Compounds; Pyrazines; Quinolines; Recombinant Proteins; Treatment Outcome | 2016 |
Synthetic Bioluminescent Coelenterazine Derivatives.
Topics: Imidazoles; Kinetics; Luciferases, Renilla; Luminescent Agents; Luminescent Measurements; Pyrazines | 2016 |
Expression and reconstitution of the bioluminescent Ca(2+) reporter aequorin in human embryonic stem cells, and exploration of the presence of functional IP3 and ryanodine receptors during the early stages of their differentiation into cardiomyocytes.
Topics: Adenosine Triphosphate; Aequorin; Blotting, Western; Caffeine; Calcium; Cell Differentiation; Cell Line; Fluorescent Dyes; HEK293 Cells; Human Embryonic Stem Cells; Humans; Imidazoles; Inositol 1,4,5-Trisphosphate Receptors; Luminescent Measurements; Myocytes, Cardiac; Potassium Chloride; Pyrazines; Ryanodine Receptor Calcium Release Channel; Time Factors | 2016 |
Bioluminescence Resonance Energy Transfer (BRET)-Based Synthetic Sensor Platform for Drug Discovery.
Topics: Animals; Antibodies; Autophagy; Autophagy-Related Proteins; Bioluminescence Resonance Energy Transfer Techniques; Biosensing Techniques; Cysteine Endopeptidases; Drug Discovery; Fluorescence; Humans; Imidazoles; Luciferases, Renilla; Microtubule-Associated Proteins; Protein Binding; Pyrazines | 2017 |
Luciferase-Specific Coelenterazine Analogues for Optical Contamination-Free Bioassays.
Topics: Bias; Imidazoles; Luciferases; Luminescent Agents; Luminescent Measurements; Molecular Structure; Pyrazines | 2017 |
Theoretically obtained insight into the mechanism and dioxetanone species responsible for the singlet chemiexcitation of Coelenterazine.
Topics: Amides; Electron Transport; Heterocyclic Compounds, 1-Ring; Imidazoles; Luminescence; Models, Chemical; Models, Molecular; Molecular Conformation; Pyrazines | 2017 |
Motoneuron activity is required for enhancements in functional recovery after peripheral nerve injury in exercised female mice.
Topics: Animals; Evoked Potentials, Motor; Female; Imidazoles; Luciferases, Renilla; Luminescent Agents; Mice, Transgenic; Motor Activity; Motor Neurons; Nerve Regeneration; Optogenetics; Peripheral Nerve Injuries; Pyrazines; Recovery of Function; Sciatic Nerve | 2020 |
Chemically activated luminopsins allow optogenetic inhibition of distributed nodes in an epileptic network for non-invasive and multi-site suppression of seizure activity.
Topics: Animals; Anterior Thalamic Nuclei; Bicuculline; Convulsants; Dentate Gyrus; Epilepsy; Imidazoles; Luminescent Agents; Male; Neural Inhibition; Neural Pathways; Opsins; Optogenetics; Pyrazines; Rats, Sprague-Dawley; Seizures | 2018 |
Coelenterazine analogues emit red-shifted bioluminescence with NanoLuc.
Topics: Imidazoles; Luciferases; Luminescent Agents; Luminescent Measurements; Molecular Structure; Pyrazines | 2017 |
Bioluminescence Resonance Energy Transfer Assay to Characterize Gi-Like G Protein Subtype-Dependent Functional Selectivity.
Topics: Bioluminescence Resonance Energy Transfer Techniques; Gene Expression Regulation; GTP-Binding Protein alpha Subunits, Gi-Go; HEK293 Cells; Humans; Imidazoles; Luminescent Agents; Polyethyleneimine; Protein Transport; Pyrazines; Receptors, G-Protein-Coupled; Signal Transduction; Transfection | 2017 |
A coelenterazine-type bioluminescent probe for nitroreductase imaging.
Topics: Dose-Response Relationship, Drug; Fluorescent Dyes; Humans; Imidazoles; Molecular Structure; Nitroreductases; Pyrazines; Structure-Activity Relationship; Tumor Cells, Cultured | 2017 |
Bioluminescence-driven optogenetic activation of transplanted neural precursor cells improves motor deficits in a Parkinson's disease mouse model.
Topics: Animals; Disease Models, Animal; Female; Imidazoles; Luminescent Agents; Luminescent Measurements; Luminescent Proteins; Male; Mice, Transgenic; Motor Activity; Neural Stem Cells; Opsins; Optogenetics; Parkinson Disease; Pyrazines; Rotarod Performance Test | 2020 |
Azide- and Dye-Conjugated Coelenterazine Analogues for a Multiplex Molecular Imaging Platform.
Topics: Animals; Azides; Chlorocebus aethiops; COS Cells; Fluorescent Dyes; Imidazoles; Luciferases; Luminescent Agents; Luminescent Measurements; Molecular Imaging; Pyrazines | 2018 |
Monitoring brain activity and behaviour in freely moving Drosophila larvae using bioluminescence.
Topics: Aequorin; Animals; Animals, Genetically Modified; Brain; Calcium; Drosophila; Imidazoles; Larva; Luminescence; Nervous System Physiological Phenomena; Pyrazines | 2018 |
Novel photoactivatable substrates for Renilla luciferase imaging in vitro and in vivo.
Topics: Animals; Imidazoles; Luciferases, Renilla; Luminescent Agents; Luminescent Measurements; Mice; Mice, Nude; Molecular Structure; Neoplasms, Experimental; Optical Imaging; Photochemical Processes; Pyrazines; Substrate Specificity; Ultraviolet Rays | 2018 |
New Optical Imaging Reporter-labeled Anaplastic Thyroid Cancer-Derived Extracellular Vesicles as a Platform for In Vivo Tumor Targeting in a Mouse Model.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Disease Models, Animal; Drug Carriers; Extracellular Vesicles; Female; Genes, Reporter; Humans; Imidazoles; Luciferases, Renilla; Luminescent Agents; Mice; Mice, Nude; Optical Imaging; Pyrazines; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms; Xenograft Model Antitumor Assays | 2018 |
Comparative study of the chemiluminescence of coelenterazine, coelenterazine-e and Cypridina luciferin with an experimental and theoretical approach.
Topics: Heterocyclic Compounds, 1-Ring; Hydrogen-Ion Concentration; Imidazoles; Luciferases; Luminescence; Luminescent Agents; Pyrazines; Solvents | 2019 |
Gram-scale synthesis of luciferins derived from coelenterazine and original insights into their bioluminescence properties.
Topics: Acetylation; Animals; Fireflies; Firefly Luciferin; Imidazoles; Luciferases, Firefly; Luminescent Measurements; Molecular Structure; Pyrazines | 2019 |
Bioluminescence resonance energy transfer-based imaging of protein-protein interactions in living cells.
Topics: Animals; Bacterial Proteins; Benzeneacetamides; beta-Arrestin 2; Fluorescence Resonance Energy Transfer; Gene Expression; Green Fluorescent Proteins; HEK293 Cells; Humans; Imidazoles; Luminescent Measurements; Luminescent Proteins; Membrane Proteins; Optical Imaging; Plasmids; Protein Interaction Mapping; Pyrazines; Receptors, Vasopressin; Recombinant Fusion Proteins; Renilla; Transfection | 2019 |
Near-Infrared Bioluminescence Imaging with a through-Bond Energy Transfer Cassette.
Topics: Carbocyanines; Energy Transfer; Imidazoles; Infrared Rays; Luminescent Agents; Luminescent Measurements; Molecular Structure; Pyrazines | 2019 |
Multiplexing cytokine analysis: towards reducing sample volume needs in clinical diagnostics.
Topics: Aequorin; Animals; Goats; Humans; Hydrozoa; Imidazoles; Immunoassay; Immunoglobulin G; Interleukin-6; Interleukin-9; Limit of Detection; Luminescence; Luminescent Measurements; Mice; Mutation; Pyrazines; Reproducibility of Results; Tumor Necrosis Factor-alpha | 2019 |
Highly bright and stable NIR-BRET with blue-shifted coelenterazine derivatives for deep-tissue imaging of molecular events
Topics: Amino Acid Sequence; Animals; Binding Sites; Breast Neoplasms; Chlorocebus aethiops; COS Cells; Female; Fluorescence Resonance Energy Transfer; HeLa Cells; Heterografts; Humans; Imidazoles; Liver Neoplasms; Luciferases; Luminescent Agents; Luminescent Measurements; Luminescent Proteins; Lung Neoplasms; Mice; Models, Molecular; Molecular Imaging; Protein Binding; Protein Interaction Domains and Motifs; Protein Structure, Secondary; Pyrazines; Receptors, Estrogen; Recombinant Fusion Proteins; Red Fluorescent Protein; Single-Cell Analysis | 2019 |
Biothiol-Activatable Bioluminescent Coelenterazine Derivative for Molecular Imaging in Vitro and in Vivo.
Topics: Animals; Chlorocebus aethiops; COS Cells; Imidazoles; Luminescent Agents; Luminescent Measurements; Molecular Imaging; Molecular Structure; Optical Imaging; Pyrazines; Sensilla; Sulfhydryl Compounds | 2019 |
Development of a quantitative method to measure EV uptake.
Topics: Biological Transport; Breast Neoplasms; Cell Line, Tumor; Extracellular Vesicles; Female; Genes, Reporter; Green Fluorescent Proteins; High-Throughput Screening Assays; Humans; Imidazoles; Luciferases, Renilla; Luminescent Measurements; Nanoparticles; Pyrazines; Recombinant Fusion Proteins; Sensitivity and Specificity; Subcellular Fractions; Tetraspanin 29; Tetraspanin 30 | 2019 |
Study of the Combination of Self-Activating Photodynamic Therapy and Chemotherapy for Cancer Treatment.
Topics: Antineoplastic Agents; Cell Proliferation; Cell Survival; Drug Screening Assays, Antitumor; Humans; Imidazoles; MCF-7 Cells; Molecular Structure; PC-3 Cells; Photochemotherapy; Photosensitizing Agents; Pyrazines; Tumor Cells, Cultured | 2019 |
Single-molecule chemiluminescent photosensitizer for a self-activating and tumor-selective photodynamic therapy of cancer.
Topics: Cell Line, Tumor; Cell Survival; Computer Simulation; Humans; Imidazoles; Light; Neoplasms; Photochemotherapy; Photosensitizing Agents; Proof of Concept Study; Pyrazines; Singlet Oxygen; Thermodynamics | 2019 |
The BioLuminescent-OptoGenetic in vivo response to coelenterazine is proportional, sensitive, and specific in neocortex.
Topics: Animals; Channelrhodopsins; Female; Imidazoles; Luminescent Agents; Luminescent Measurements; Luminescent Proteins; Male; Mice, Inbred C57BL; Neocortex; Neurons; Opsins; Optogenetics; Pyrazines; Reproducibility of Results | 2020 |
Improved trafficking and expression of luminopsins for more efficient optical and pharmacological control of neuronal activity.
Topics: Animals; Behavior, Animal; Female; Imidazoles; Luciferases; Luminescent Agents; Luminescent Measurements; Male; Membrane Potentials; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Opsins; Optogenetics; Primary Cell Culture; Protein Transport; Pyrazines; Somatosensory Cortex | 2020 |
Reflector of the body photophore in lanternfish is mechanistically tuned to project the biochemical emission in photocytes for counterillumination.
Topics: Animals; Biological Mimicry; Blood Platelets; Fishes; Guanine; Imidazoles; Luciferases; Luminescence; Pyrazines; Spectroscopy, Fourier Transform Infrared; X-Ray Diffraction | 2020 |
Bioluminescent Protein-Inhibitor Pair in the Design of a Molecular Aptamer Beacon Biosensing System.
Topics: Animals; Aptamers, Nucleotide; Biosensing Techniques; Copepoda; Enzyme Inhibitors; Imidazoles; Luciferases; Luminescent Measurements; Luminescent Proteins; Models, Molecular; Molecular Structure; Pyrazines; Signal-To-Noise Ratio | 2020 |
Luminescence Activity Decreases When v-coelenterazine Replaces Coelenterazine in Calcium-Regulated Photoprotein-A Theoretical and Experimental Study.
Topics: Calcium; Imidazoles; Luminescent Measurements; Luminescent Proteins; Models, Theoretical; Molecular Dynamics Simulation; Protein Conformation; Pyrazines; Quantum Theory | 2020 |
Bioluminescent Properties of Semi-Synthetic Obelin and Aequorin Activated by Coelenterazine Analogues with Modifications of C-2, C-6, and C-8 Substituents.
Topics: Aequorin; Animals; Calcium; Hydrogen Bonding; Imidazoles; Luminescent Proteins; Mutagenesis, Site-Directed; Protein Conformation; Pyrazines | 2020 |
A putative chordate luciferase from a cosmopolitan tunicate indicates convergent bioluminescence evolution across phyla.
Topics: Animals; Biological Evolution; Chordata; Computational Biology; Evolution, Molecular; Gene Expression Profiling; Imidazoles; Luciferases; Luminescence; Luminescent Measurements; Models, Molecular; Phylogeny; Pyrazines; Sequence Alignment; Sequence Analysis, DNA; Species Specificity; Urochordata | 2020 |
Stability Studies of New Caged bis-deoxy-coelenterazine Derivatives and Their Potential Use as Cellular pH Probes.
Topics: Half-Life; Hydrogen-Ion Concentration; Hydrolysis; Imidazoles; Kinetics; Magnetic Resonance Spectroscopy; Molecular Probes; Pyrazines; Thermodynamics | 2021 |
Long-term single cell bioluminescence imaging with C-3 position protected coelenterazine analogues.
Topics: Animals; Cell Line; Humans; Imidazoles; Luminescence; Optical Imaging; Pyrazines; Single-Cell Analysis | 2021 |
Solution structure of Gaussia Luciferase with five disulfide bonds and identification of a putative coelenterazine binding cavity by heteronuclear NMR.
Topics: Amino Acid Sequence; Animals; Copepoda; Disulfides; Imidazoles; Luciferases; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Protein Domains; Protein Folding; Pyrazines | 2020 |
Coelenterazine Analogue with Human Serum Albumin-Specific Bioluminescence.
Topics: Alkylation; Humans; Imidazoles; Luminescence; Pyrazines; Serum Albumin, Human | 2020 |
Flash properties of Gaussia luciferase are the result of covalent inhibition after a limited number of cycles.
Topics: Animals; Copepoda; Escherichia coli; Imidazoles; Kinetics; Luciferases; Pyrazines; Recombinant Proteins; Spectrometry, Fluorescence | 2021 |
Near-Infrared Bioluminescence Imaging of Animal Cells with Through-Bond Energy Transfer Cassette.
Topics: Animals; Carbocyanines; Chlorocebus aethiops; COS Cells; Energy Transfer; Imidazoles; Luciferases; Luminescent Agents; Luminescent Measurements; Molecular Imaging; Pyrazines; Spectroscopy, Near-Infrared | 2021 |
Luciferase-Specific Coelenterazine Analogues for Optical Cross Talk-Free Bioassays.
Topics: Alkynes; Animals; Chlorocebus aethiops; COS Cells; Estrogen Receptor Modulators; Imidazoles; Immunosuppressive Agents; Luciferases; Luminescent Agents; Luminescent Measurements; Optical Imaging; Pyrazines; Sirolimus; Styrenes | 2021 |
Highly Bright NIR-BRET System for Imaging Molecular Events in Live Cells.
Topics: Animals; Apoptosis; Breast Neoplasms; Cell Proliferation; Female; Fluorescence Resonance Energy Transfer; Humans; Imidazoles; Luciferases; Luminescent Agents; Luminescent Measurements; Mice; Mice, Inbred NOD; Mice, SCID; Optical Imaging; Pyrazines; Spectroscopy, Near-Infrared; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2021 |
Bioluminescent Optogenetics: A Novel Experimental Therapy to Promote Axon Regeneration after Peripheral Nerve Injury.
Topics: Animals; Axons; Disease Models, Animal; Evoked Potentials, Motor; Female; Humans; Imidazoles; Luminescent Agents; Luminescent Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Neurons; Nerve Regeneration; Optogenetics; Peripheral Nerve Injuries; Pyrazines; Recombinant Fusion Proteins; Regenerative Medicine | 2021 |
Mix-and-read bioluminescent copper detection platform using a caged coelenterazine analogue.
Topics: Copper; Humans; Imidazoles; Luciferases; Pyrazines | 2021 |
Etmopterus lantern sharks use coelenterazine as the substrate for their luciferin-luciferase bioluminescence system.
Topics: Animals; Chromatography, Liquid; Fish Proteins; Hydrogen-Ion Concentration; Imidazoles; Luciferases; Luminescence; Luminescent Measurements; Methanol; Pyrazines; Sharks; Skin; Species Specificity; Substrate Specificity; Tandem Mass Spectrometry | 2021 |
Enzymatic conversion of dehydrocoelenterazine to coelenterazine using FMN-bound flavin reductase of NAD(P)H:FMN oxidoreductase.
Topics: Aliivibrio fischeri; Animals; Bacterial Proteins; Biocatalysis; Biotransformation; Chromatography, High Pressure Liquid; Flavin Mononucleotide; Gene Expression; Imidazoles; Kinetics; Luciferases; Luminescence; Luminescent Measurements; NADH, NADPH Oxidoreductases; Phenylpyruvic Acids; Pyrazines; Renilla | 2022 |
Theoretical Study of the Thermolysis Reaction and Chemiexcitation of Coelenterazine Dioxetanes.
Topics: Imidazoles; Luminescent Measurements; Models, Theoretical; Pyrazines | 2022 |
Synthetic Coelenterazine Derivatives and Their Application for Bioluminescence Imaging.
Topics: Diagnostic Imaging; Imidazoles; Luminescent Measurements; Pyrazines | 2022 |
Comparative Investigation of the Chemiluminescent Properties of a Dibrominated Coelenterazine Analog.
Topics: Imidazoles; Luminescence; Luminescent Measurements; Pyrazines; Superoxides | 2022 |
Reverse mutants of the catalytic 19 kDa mutant protein (nanoKAZ/nanoLuc) from Oplophorus luciferase with coelenterazine as preferred substrate.
Topics: Amino Acids; Animals; Decapoda; Imidazoles; Luciferases; Luciferases, Renilla; Luminescent Measurements; Mutant Proteins; Pyrazines | 2022 |
Coelenterazine sulfotransferase from Renilla muelleri.
Topics: Animals; Arylsulfotransferase; Chromatography, Liquid; DNA, Complementary; Escherichia coli; Imidazoles; Luciferases; Luminescent Measurements; Proteomics; Pyrazines; Renilla; Sulfates; Sulfotransferases; Tandem Mass Spectrometry | 2022 |
C-Series Coelenterazine-Driven Bioluminescence Signature Imaging.
Topics: Indicators and Reagents; Luciferases; Luminescent Measurements; Pyrazines | 2022 |
S-Series Coelenterazine-Driven Combinatorial Bioluminescence Imaging Systems for Mammalian Cells.
Topics: Animals; Imidazoles; Ligands; Luciferases; Luminescent Measurements; Mammals; Pyrazines | 2023 |
Coelenterazine Indicators for the Specific Imaging of Human and Bovine Serum Albumins.
Topics: Humans; Imidazoles; Protein Binding; Pyrazines; Serum Albumin; Serum Albumin, Bovine; Serum Albumin, Human; Spectrometry, Fluorescence | 2023 |