Compounds > pyrazines
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pyrazines and casein kinase ii

pyrazines has been researched along with casein kinase ii in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's4 (80.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cluzeau, J; Fujii, N; Hara, T; Hirasawa, A; Ohno, H; Oishi, S; Suzuki, Y; Tsujimoto, G1
Fuchi, N; Fujii, S; Iura, Y; Kaneko, H; Nishimura, K; Nitta, A; Sekiya, Y; Suyama, K; Takahashi, T; Ueda, H; Yamada, M; Yamaguchi, S1
Adami, F; Brancalion, A; Cabrelle, A; Cappellesso, R; Colpo, A; Di Maggio, SA; Gurrieri, C; Mandato, E; Manni, S; Marino, F; Piazza, F; Pizzi, M; Semenzato, G; Trentin, L; Tubi, LQ; Zaffino, F; Zambello, R1
Fuchi, N; Hirasawa, A; Hou, Z; Liu, N; Miyamoto, Y; Ohno, H; Oshida, K; Shi, J; Suzuki, Y; Takei, Y; Tsujimoto, G; Xiao, Y; Yamada, M; Yasue, M1
Bao, L; Block, MH; Cooke, E; Dakin, LA; Denz, CR; Dowling, JE; Ferguson, AD; Gingipalli, L; Johannes, JW; Lamb, ML; Larsen, NA; Lyne, PD; Pontz, TW; Wang, T; Wu, A; Wu, X; Zhang, HJ; Zheng, X1

Other Studies

5 other study(ies) available for pyrazines and casein kinase ii

ArticleYear
Structure-activity relationships of pyrazine-based CK2 inhibitors: synthesis and evaluation of 2,6-disubstituted pyrazines and 4,6-disubstituted pyrimidines.
    Archiv der Pharmazie, 2008, Volume: 341, Issue:9

    Topics: Casein Kinase II; Enzyme Inhibitors; Indicators and Reagents; Pyrazines; Pyrimidines; Structure-Activity Relationship

2008
Discovery and structure-activity relationship of 2,6-disubstituted pyrazines, potent and selective inhibitors of protein kinase CK2.
    Bioorganic & medicinal chemistry letters, 2012, Jul-01, Volume: 22, Issue:13

    Topics: Animals; Binding Sites; Casein Kinase II; Computer Simulation; Disease Models, Animal; Drug Evaluation, Preclinical; Humans; Indazoles; Injections, Intraperitoneal; Nephritis; Protein Kinase Inhibitors; Protein Structure, Tertiary; Pyrazines; Rats; Structure-Activity Relationship

2012
Protein kinase CK2 inhibition down modulates the NF-κB and STAT3 survival pathways, enhances the cellular proteotoxic stress and synergistically boosts the cytotoxic effect of bortezomib on multiple myeloma and mantle cell lymphoma cells.
    PloS one, 2013, Volume: 8, Issue:9

    Topics: Adenosine Triphosphate; Analysis of Variance; Apoptosis; Base Sequence; Blotting, Western; Boronic Acids; Bortezomib; Casein Kinase II; Cell Line, Tumor; DNA Primers; Humans; Immunohistochemistry; Leukocytes, Mononuclear; Lymphoma, Mantle-Cell; Molecular Sequence Data; Multiple Myeloma; Naphthyridines; NF-kappa B; Phenazines; Pyrazines; Real-Time Polymerase Chain Reaction; RNA Interference; Signal Transduction; STAT3 Transcription Factor

2013
The Effects of a Selective CK2 Inhibitor on Anti-glomerular Basement Membrane Glomerulonephritis in Rats.
    Biological & pharmaceutical bulletin, 2015, Volume: 38, Issue:9

    Topics: Animals; Apoptosis; Blood Urea Nitrogen; Casein Kinase II; Creatinine; Emodin; Glomerulonephritis; Kidney Glomerulus; Male; Protein Kinase Inhibitors; Proteinuria; Pyrazines; Rats, Inbred WKY; Testis

2015
Discovery of 2,6-disubstituted pyrazine derivatives as inhibitors of CK2 and PIM kinases.
    Bioorganic & medicinal chemistry letters, 2018, 05-01, Volume: 28, Issue:8

    Topics: Casein Kinase II; Cell Line, Tumor; Drug Design; Humans; Molecular Structure; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-pim-1; Pyrazines; Structure-Activity Relationship

2018