pyrazines has been researched along with cardiovascular agents in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.14) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 7 (50.00) | 29.6817 |
| 2010's | 5 (35.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zeng, GY; Zhang, LY; Zhang, Y; Zhou, YP | 1 |
| Bonnet, PA; Boucard, M; Chapat, JP; Laurent, F; Michel, A | 1 |
| Liao, F | 1 |
| Chang, LG; Minamiyama, M | 1 |
| Poole-Wilson, PA; van Veldhuisen, DJ | 1 |
| Ackermann, C; Hou, H; Qi, X; Sheng, M; Sun, D | 1 |
| Qi-Neng, P; Yan-Yu, X; Zhi-Peng, C | 1 |
| Ho, JW; Jie, M | 1 |
| Chawla, PS; Kochar, MS | 1 |
| Chen, H; Li, G; Liu, X; Zhan, P | 1 |
| Li, J; Lu, J; Wan, H; Yang, J; Zhang, Y; Zhu, Z | 1 |
| Chen, H; Deng, L; Guo, X; Liu, X; Song, Y; Wu, J; Zhai, L; Zhan, P | 1 |
| Cui, L; Li, Z; Liu, X; Shen, Y; Wang, S; Yu, F; Zhan, P | 1 |
| Chen, W; Cui, L; Li, Z; Liu, X; Shen, Y; Wang, S; Yu, F; Zhan, P | 1 |
4 review(s) available for pyrazines and cardiovascular agents
| Article | Year |
|---|---|
Herbs of activating blood circulation to remove blood stasis.
Topics: Aged; Animals; Anticoagulants; Blood Viscosity; Cardiovascular Agents; Coronary Disease; Drugs, Chinese Herbal; Fibrinolytic Agents; Hemodynamics; Hemorheology; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyrazines; Rats; Rats, Wistar; Stroke; Thrombosis | 2000 |
The underreporting of results and possible mechanisms of 'negative' drug trials in patients with chronic heart failure.
Topics: Bosentan; Cardiovascular Agents; Deoxyepinephrine; Heart Failure; Humans; Imidazoles; Mibefradil; Pyrazines; Quinolines; Sulfonamides; Xamoterol | 2001 |
Pharmacological activity of cardiovascular agents from herbal medicine.
Topics: Alkaloids; Astragalus propinquus; Biphenyl Compounds; Cardiovascular Agents; Drugs, Chinese Herbal; Flavonoids; Glycyrrhizic Acid; Herbal Medicine; Humans; Lignans; Phenanthrenes; Pyrazines | 2007 |
What's new in clinical pharmacology and therapeutics.
Topics: Abatacept; Acetanilides; Amides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antiparkinson Agents; Antirheumatic Agents; Antiviral Agents; Apomorphine; Benzazepines; Cardiovascular Agents; Fumarates; Hepatitis B; Human Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18; Humans; Hypoglycemic Agents; Immunoconjugates; Multiple Sclerosis; Natalizumab; Nucleosides; Papillomavirus Vaccines; Pharmacology, Clinical; Piperazines; Pyrazines; Pyrimidinones; Quinoxalines; Ranolazine; Sitagliptin Phosphate; Smoking Cessation; Telbivudine; Thymidine; Triazoles; Varenicline; Viral Vaccines | 2008 |
10 other study(ies) available for pyrazines and cardiovascular agents
| Article | Year |
|---|---|
[Effects of tetramethylpyrazine on cardiac haemodynamics in dogs (author's transl)].
Topics: Animals; Cardiovascular Agents; Dogs; Hemodynamics; Oxygen Consumption; Propranolol; Pyrazines; Reserpine | 1982 |
Pharmacological activities of imidazo[1,2-alpha]pyrazine derivatives.
Topics: Adenosine; Animals; Calcium; Cardiovascular Agents; Cattle; Diuresis; Guinea Pigs; Heart Atria; Heart Rate; Ileum; Imidazoles; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Myocardial Contraction; Parasympatholytics; Phosphodiesterase Inhibitors; Pyrazines; Rabbits; Rats; Rats, Wistar; Theophylline; Trachea | 1995 |
Macro- and microcirculatory effects of tetramethylpyrazine and extract of Charthamus tinctorius L. in rabbit mesentery.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Animals; Arterioles; Blood Flow Velocity; Blood Pressure; Calcium Channel Blockers; Cardiovascular Agents; Carthamus tinctorius; Drugs, Chinese Herbal; Microcirculation; Microscopy, Video; Neurotransmitter Agents; Nicardipine; Phentolamine; Pyrazines; Rabbits; Splanchnic Circulation | 2000 |
Physicochemical characterization and percutaneous delivery of 2,3,5,6-tetramethylpyrazine.
Topics: Administration, Cutaneous; Animals; Cardiovascular Agents; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Ligusticum; Mice; Mice, Hairless; Pyrazines; Rabbits; Rats; Rats, Sprague-Dawley; Skin; Skin Absorption; Solubility | 2003 |
The enhancing effect of synthetical borneol on the absorption of tetramethylpyrazine phosphate in mouse.
Topics: Administration, Oral; Animals; Biological Availability; Brain; Camphanes; Cardiovascular Agents; Computer Simulation; Dose-Response Relationship, Drug; Drug Combinations; Intestinal Absorption; Least-Squares Analysis; Male; Mice; Models, Biological; Nonlinear Dynamics; Phosphates; Pyrazines; Reproducibility of Results | 2007 |
Ligustrazine derivatives. Part 5: design, synthesis and biological evaluation of novel ligustrazinyloxy-cinnamic acid derivatives as potent cardiovascular agents.
Topics: Animals; Cardiovascular Agents; Cell Line; Chemistry Techniques, Synthetic; Cinnamates; Cytoprotection; Drug Design; Endothelial Cells; Platelet Aggregation; Pyrazines; Rabbits; Structure-Activity Relationship | 2011 |
Synergistic protective effect of astragaloside IV-tetramethylpyrazine against cerebral ischemic-reperfusion injury induced by transient focal ischemia.
Topics: Animals; Astragalus Plant; Cardiovascular Agents; Caspase 3; Disease Models, Animal; Drug Synergism; Glucose; Hippocampus; Ischemic Attack, Transient; Male; Malondialdehyde; Neuroprotective Agents; Nimodipine; Nitric Oxide Synthase Type II; Phytotherapy; Plant Extracts; Positron-Emission Tomography; Proto-Oncogene Proteins c-bcl-2; Pyrazines; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; RNA, Messenger; Saponins; Superoxide Dismutase; Triterpenes | 2012 |
Ligustrazine derivatives. Part 4: design, synthesis, and biological evaluation of novel ligustrazine-based stilbene derivatives as potential cardiovascular agents.
Topics: Cardiovascular Agents; Drug Design; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Peroxide; Oxidative Stress; Pyrazines; Stilbenes; Structure-Activity Relationship | 2012 |
Ligustrazine derivatives. Part 6: design, synthesis and evaluation of novel ligustrazinyl acylguanidine derivatives as potential cardiovascular agents.
Topics: Antioxidants; Cardiovascular Agents; Cell Line; Cell Proliferation; Cell Survival; Drug Design; Endothelial Cells; Guanidines; Humans; Inhibitory Concentration 50; Pyrazines; Structure-Activity Relationship | 2012 |
Ligustrazine derivatives. Part 8: design, synthesis, and preliminary biological evaluation of novel Ligustrazinyl amides as cardiovascular agents.
Topics: Amides; Cardiovascular Agents; Cells, Cultured; Drug Design; Endothelial Cells; Humans; Pyrazines; Structure-Activity Relationship | 2014 |