pyrazines has been researched along with carbon tetrachloride in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 5 (50.00) | 24.3611 |
| 2020's | 2 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fu, QL | 1 |
| Kim, ND; Kim, SG; Kwak, MK | 1 |
| Li, XS; Liu, LY; Liu, ZQ; Tan, LX | 1 |
| Li, S; Lu, B; Si, S; Yu, L; Zeng, Y | 1 |
| Lu, C; Shao, J; Xu, W; Zhang, F; Zheng, S | 1 |
| Lin, Q; Qian, L; Shao, J; Zhang, C; Zhang, F; Zhang, Z; Zhao, S; Zheng, S | 1 |
| Chen, A; Hao, M; Jin, H; Lian, N; Shao, J; Wu, L; Yao, Z; Zhang, F; Zheng, S | 1 |
| Chen, A; Shao, J; Yao, Z; Zhang, F; Zhang, Z; Zhao, S; Zheng, S | 1 |
| Guo, Z; He, S; Hu, Z; Jiang, K; Lin, C; Su, H; Yuan, G; Zeng, Y; Zhong, F | 1 |
| Li, D; Li, X; Liu, H; Wang, M; Wu, Z; Xie, F; Xu, C; Zhang, X; Zhao, W | 1 |
10 other study(ies) available for pyrazines and carbon tetrachloride
| Article | Year |
|---|---|
[Experimental study on yiqi-huoxue therapy of liver fibrosis].
Topics: Alanine Transaminase; Animals; Astragalus propinquus; Carbon Tetrachloride; Collagen; Drugs, Chinese Herbal; Female; Fibrinolytic Agents; Liver; Liver Cirrhosis; Male; Pyrazines; Rats; Rats, Inbred Strains | 1992 |
Inhibition of cytochrome P450 2E1 expression by 2-(allylthio)pyrazine, a potential chemoprotective agent: hepatoprotective effects.
Topics: Animals; Carbon Tetrachloride; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Enzyme Inhibitors; Female; Glutathione; Liver; Male; Mice; Mice, Inbred ICR; Pyrazines; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1997 |
[Effects of combination therapy of rehin and tetramethylpyrazine on experimental hepatic fibrosis induced by tetrachloride].
Topics: Animals; Anthraquinones; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Drug Therapy, Combination; Liver Cirrhosis, Experimental; Male; Pyrazines; Rats; Rats, Wistar | 2004 |
Alleviation of CCl4-induced cirrhosis in rats by tetramethylpyrazine is associated with downregulation of leptin and TGF-beta1 pathway.
Topics: Animals; Blotting, Western; Carbon Tetrachloride; Down-Regulation; Fibrinolytic Agents; Histocytochemistry; Leptin; Liver Cirrhosis; Male; Pyrazines; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Leptin; Receptors, Transforming Growth Factor beta; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Smad3 Protein; Smad7 Protein; Transforming Growth Factor beta1 | 2010 |
Nrf2 knockdown attenuates the ameliorative effects of ligustrazine on hepatic fibrosis by targeting hepatic stellate cell transdifferentiation.
Topics: Animals; beta Catenin; Carbon Tetrachloride; Cell Line; Cell Transdifferentiation; Gene Knockdown Techniques; Genetic Therapy; Hepatic Stellate Cells; Humans; Liver; Liver Cirrhosis; Male; Mice, Inbred ICR; NF-E2-Related Factor 2; Pyrazines | 2016 |
Tetramethylpyrazine attenuates carbon tetrachloride-caused liver injury and fibrogenesis and reduces hepatic angiogenesis in rats.
Topics: Angiogenesis Inhibitors; Animals; Apoptosis; bcl-2-Associated X Protein; Becaplermin; Carbon Tetrachloride; Down-Regulation; Endothelial Cells; Hepatocytes; Liver; Liver Cirrhosis; Male; Neovascularization, Pathologic; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-sis; Pyrazines; Rats; Rats, Sprague-Dawley; Receptors, Platelet-Derived Growth Factor; Up-Regulation; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2 | 2017 |
Canonical hedgehog signalling regulates hepatic stellate cell-mediated angiogenesis in liver fibrosis.
Topics: Animals; Benzoquinones; Carbon Tetrachloride; Disease Models, Animal; Hedgehog Proteins; Hepatic Stellate Cells; HSP90 Heat-Shock Proteins; Hypoxia-Inducible Factor 1, alpha Subunit; Lactams, Macrocyclic; Liver Cirrhosis; Male; Mice; Mice, Inbred ICR; Mustard Compounds; Neovascularization, Pathologic; Phenylpropionates; Pyrazines; Rats; Rats, Sprague-Dawley; Signal Transduction; Smoothened Receptor | 2017 |
Tetramethylpyrazine attenuates sinusoidal angiogenesis via inhibition of hedgehog signaling in liver fibrosis.
Topics: Animals; Carbon Tetrachloride; Cell Proliferation; Gene Expression Regulation; Hedgehog Proteins; Humans; Liver Cirrhosis; Mice; Neovascularization, Pathologic; Nitric Oxide; Nitric Oxide Synthase; Primary Cell Culture; Pyrazines; Smoothened Receptor | 2017 |
Tetramethylpyrazine ameliorates hepatic fibrosis through autophagy-mediated inflammation.
Topics: Animals; Autophagy; Carbon Tetrachloride; Cell Line, Tumor; Chromones; Chronic Disease; Fibrinolytic Agents; Hepatic Stellate Cells; Inflammation; Liver Cirrhosis; Male; Microscopy, Fluorescence; Morpholines; Phosphatidylinositol 3-Kinases; Platelet-Derived Growth Factor; Pyrazines; Rats; Rats, Sprague-Dawley; Signal Transduction | 2020 |
Lack of Mof reduces acute liver injury by enhancing transcriptional activation of Igf1.
Topics: Acute Disease; Adenoviridae; Animals; Carbon Tetrachloride; Cell Line, Tumor; Gene Knockdown Techniques; Histone Acetyltransferases; Imidazoles; Insulin-Like Growth Factor I; Liver; Liver Regeneration; Mice, Inbred C57BL; Promoter Regions, Genetic; Protein Binding; Pyrazines; Signal Transduction; Transcriptional Activation | 2021 |