Page last updated: 2024-08-21

pyrazines and calpain

pyrazines has been researched along with calpain in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (10.00)18.2507
2000's4 (40.00)29.6817
2010's4 (40.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Alvarez, ME; Cooper, R; Gillum, AM; Gregory, J; Harris, A; Kydd, GC; Sun, HH; White, CB1
An, WG; Blagosklonny, MV; Hwang, SG; Trepel, JB1
Aubé, J; Hanzlik, RP; Li, Q; Zeng, Y1
Dale, Y; Eltom, SE1
Anderson, KC; Antón, IM; Calamito, M; de la Fuente, MA; Elkhal, A; Gallego, MD; Geha, RS; Ochs, HD; Ramesh, N; Rosen, FS; Sasahara, Y; Siminovitch, K; Suresh, K1
Chen, S; Deng, X; Khuri, FR; Li, C; Lonial, S; Sun, SY; Yue, P1
Agten, A; Cielen, N; Decramer, M; Dekhuijzen, RP; Gayan-Ramirez, G; Maes, K; Thomas, D; Van Hees, HW1
Dorr, RT; Escalante, AM; Karolak, MR; Landowski, TH; Lynch, RM; McGrath, RT1
Chang, H; Gao, Y; Goswami, N; Hinghofer-Szalkay, H; Li, G; Li, Y; Ma, X; Wang, H; Zhang, J1
Chen, J; Ji, Y; Li, W; Ma, H; Ma, Y; Shen, J; Shen, Y; Su, SA; Wang, Y; Xiang, M; Xie, Y; Zhang, Y1

Other Studies

10 other study(ies) available for pyrazines and calpain

ArticleYear
Phevalin, a new calpain inhibitor, from a Streptomyces sp.
    The Journal of antibiotics, 1995, Volume: 48, Issue:10

    Topics: Calpain; Pyrazines; Streptomyces

1995
Protease inhibitor-induced apoptosis: accumulation of wt p53, p21WAF1/CIP1, and induction of apoptosis are independent markers of proteasome inhibition.
    Leukemia, 2000, Volume: 14, Issue:7

    Topics: Acetylcysteine; Acrylates; Amino Acid Chloromethyl Ketones; Apoptosis; Boronic Acids; Bortezomib; Calpain; Cathepsins; Cell Division; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cysteine Endopeptidases; Drug Synergism; Genes, p53; Humans; Jurkat Cells; Leupeptins; Multienzyme Complexes; Neoplasm Proteins; Neoplasms; Oligopeptides; Protease Inhibitors; Proteasome Endopeptidase Complex; Pyrazines; Tumor Cells, Cultured; Tumor Suppressor Protein p53; U937 Cells

2000
Synthesis of a small library of diketopiperazines as potential inhibitors of calpain.
    Bioorganic & medicinal chemistry letters, 2005, Jun-15, Volume: 15, Issue:12

    Topics: Calpain; Combinatorial Chemistry Techniques; Cysteine Proteinase Inhibitors; Diketopiperazines; Humans; Molecular Structure; Peptide Library; Piperazines; Pyrazines; Recombinant Proteins; Structure-Activity Relationship

2005
The induction of CYP1A1 by oltipraz is mediated through calcium-dependent-calpain.
    Toxicology letters, 2006, Oct-10, Volume: 166, Issue:2

    Topics: Animals; Anticarcinogenic Agents; Calcium; Calpain; Cell Line, Tumor; Cytochrome P-450 CYP1A1; Down-Regulation; Enzyme Induction; Female; Humans; Immunohistochemistry; Mice; Microscopy, Fluorescence; Pyrazines; Receptors, Aryl Hydrocarbon; Reverse Transcriptase Polymerase Chain Reaction; Thiones; Thiophenes

2006
WIP is a chaperone for Wiskott-Aldrich syndrome protein (WASP).
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Jan-16, Volume: 104, Issue:3

    Topics: Actins; Animals; Arginine; Boronic Acids; Bortezomib; Calpain; Carrier Proteins; Cytoskeletal Proteins; Enzyme Inhibitors; Humans; Interleukin-2; Intracellular Signaling Peptides and Proteins; Jurkat Cells; Lymphocytes; Mice; Mice, Knockout; Molecular Chaperones; Mutation, Missense; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Binding; Pyrazines; Wiskott-Aldrich Syndrome; Wiskott-Aldrich Syndrome Protein

2007
Proteasome inhibitor PS-341 (bortezomib) induces calpain-dependent IkappaB(alpha) degradation.
    The Journal of biological chemistry, 2010, May-21, Volume: 285, Issue:21

    Topics: Active Transport, Cell Nucleus; Apoptosis; Boronic Acids; Bortezomib; Calpain; Caspase 8; Cell Line, Tumor; Cell Nucleus; Humans; I-kappa B Proteins; Multiple Myeloma; NF-KappaB Inhibitor alpha; Protease Inhibitors; Pyrazines; Transcription Factor RelA

2010
Bortezomib partially protects the rat diaphragm from ventilator-induced diaphragm dysfunction.
    Critical care medicine, 2012, Volume: 40, Issue:8

    Topics: Animals; Boronic Acids; Bortezomib; Calpain; Caspase 3; Diaphragm; Male; Muscle Contraction; Muscular Atrophy; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrazines; Rats; Rats, Wistar; Respiration, Artificial

2012
Preventing the autophagic survival response by inhibition of calpain enhances the cytotoxic activity of bortezomib in vitro and in vivo.
    Cancer chemotherapy and pharmacology, 2013, Volume: 71, Issue:6

    Topics: Animals; Antineoplastic Agents; Apoptosis; Autophagy; Boronic Acids; Bortezomib; Calpain; Cell Line, Tumor; Cell Survival; Drug Synergism; HIV Protease Inhibitors; Humans; Mice; Mice, SCID; Multiple Myeloma; Nelfinavir; Pyrazines; RNA, Small Interfering; Xenograft Model Antitumor Assays

2013
Identification of the optimal dose and calpain system regulation of tetramethylpyrazine on the prevention of skeletal muscle atrophy in hindlimb unloading rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 96

    Topics: Animals; Calpain; Dose-Response Relationship, Drug; Female; Hindlimb Suspension; Muscle Contraction; Muscle, Skeletal; Muscular Atrophy; Pyrazines; Rats; Rats, Sprague-Dawley; Vasodilator Agents

2017
Piezo1-Mediated Mechanotransduction Promotes Cardiac Hypertrophy by Impairing Calcium Homeostasis to Activate Calpain/Calcineurin Signaling.
    Hypertension (Dallas, Tex. : 1979), 2021, Volume: 78, Issue:3

    Topics: Adrenergic beta-Agonists; Animals; Calcineurin; Calcium; Calcium Signaling; Calpain; Cardiomegaly; Homeostasis; Ion Channels; Isoproterenol; Mechanotransduction, Cellular; Mice; Mice, Knockout; Myocytes, Cardiac; Pyrazines; Rats; Thiadiazoles

2021