pyrazines has been researched along with bms 665053 in 3 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fotsch, C; St Jean, DJ | 1 |
| Ahuja, VT; Bronson, JJ; Hartz, RA; Huang, S; Leet, JE; Macor, JE; Shu, YZ; Vrudhula, VM; Wong, H; Zhuo, X | 1 |
| Ahuja, VT; Bronson, JJ; Grace, JE; Hartz, RA; Lodge, NJ; Macor, JE; Vrudhula, VM | 1 |
1 review(s) available for pyrazines and bms 665053
| Article | Year |
|---|---|
Mitigating heterocycle metabolism in drug discovery.
Topics: Animals; Biotransformation; Databases, Factual; Drug Discovery; Drug Interactions; Heterocyclic Compounds, 1-Ring; Heterocyclic Compounds, 4 or More Rings; Humans; Mice; Pharmaceutical Preparations; Rats | 2012 |
2 other study(ies) available for pyrazines and bms 665053
| Article | Year |
|---|---|
Comparative biotransformation of pyrazinone-containing corticotropin-releasing factor receptor-1 antagonists: minimizing the reactive metabolite formation.
Topics: Animals; Bile; Biotransformation; Glucuronic Acid; Glutathione; Humans; Liver; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Microsomes, Liver; Models, Chemical; Molecular Structure; Pyrazines; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Spectrophotometry, Ultraviolet | 2010 |
Synthesis and evaluation of prodrugs of corticotropin-releasing factor-1 (CRF
Topics: Animals; Biological Availability; Prodrugs; Pyrazines; Rats; Receptors, Corticotropin-Releasing Hormone | 2017 |