pyrazines has been researched along with betulinic acid in 5 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hajduch, M; Kvasnica, M; Sarek, J; Tislerova, I; Urban, M | 1 |
| Aggarwal, BB; Pandey, MK; Sung, B | 1 |
| Li, Z; Liu, M; Liu, T; Luo, J; Qiu, WW; Tang, J; Xu, J; Yang, F | 1 |
| Chu, FH; Han, YT; Lei, HM; Wang, PL; Wu, GR; Xu, B; Xu, X; Yan, WQ; Zhang, CZ; Zhao, R | 1 |
| Chu, F; Cui, H; Feng, W; Guo, W; Lei, H; Li, G; Li, T; Wang, P; Wang, S; Xu, B; Yang, Y; Yuan, Y; Zhang, B; Zhang, N | 1 |
5 other study(ies) available for pyrazines and betulinic acid
| Article | Year |
|---|---|
Triterpenoid pyrazines and benzopyrazines with cytotoxic activity.
Topics: Antineoplastic Agents, Phytogenic; Betulinic Acid; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Leukemia, T-Cell; Molecular Structure; Pentacyclic Triterpenes; Pyrazines; Structure-Activity Relationship; Triterpenes; Tumor Cells, Cultured | 2007 |
Betulinic acid suppresses STAT3 activation pathway through induction of protein tyrosine phosphatase SHP-1 in human multiple myeloma cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Betulinic Acid; Blotting, Western; Boronic Acids; Bortezomib; Cell Proliferation; Drug Therapy, Combination; Electrophoretic Mobility Shift Assay; Enzyme Activation; Flow Cytometry; Humans; Immunoenzyme Techniques; Immunosuppressive Agents; Interleukin-6; Janus Kinase 1; Janus Kinase 2; Luciferases; Multiple Myeloma; Pentacyclic Triterpenes; Protease Inhibitors; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Pyrazines; Signal Transduction; src-Family Kinases; STAT3 Transcription Factor; Thalidomide; Triterpenes; Tumor Cells, Cultured | 2010 |
Synthesis and biological evaluation of heterocyclic ring-fused betulinic acid derivatives as novel inhibitors of osteoclast differentiation and bone resorption.
Topics: Acid Phosphatase; Animals; Betulinic Acid; Bone Density Conservation Agents; Bone Resorption; Cathepsin K; Cell Differentiation; Cell Line; Cell Proliferation; Crystallography, X-Ray; Female; Isoenzymes; Isoxazoles; Mice; Mice, Inbred C57BL; Osteoclasts; Ovariectomy; Pentacyclic Triterpenes; Pyrazines; Pyrazoles; Pyrimidines; RANK Ligand; Rats; Structure-Activity Relationship; Tartrate-Resistant Acid Phosphatase; Thiazoles; Triterpenes | 2012 |
Combination of amino acid/dipeptide with ligustrazine-betulinic acid as antitumor agents.
Topics: Amino Acids; Anisoles; Antineoplastic Agents; Apoptosis; Betulinic Acid; Calcium; Cell Line, Tumor; Dipeptides; Drug Screening Assays, Antitumor; Humans; Membrane Potential, Mitochondrial; Pentacyclic Triterpenes; Pyrazines; Structure-Activity Relationship; Triterpenes | 2017 |
BA-12 Inhibits Angiogenesis via Glutathione Metabolism Activation.
Topics: Animals; Betulinic Acid; Caenorhabditis elegans; Chorioallantoic Membrane; Drug Discovery; Human Umbilical Vein Endothelial Cells; Humans; Metabolomics; Neovascularization, Pathologic; Pentacyclic Triterpenes; Pyrazines; Triterpenes | 2019 |