Compounds > pyrazines
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pyrazines and bay 11-7082

pyrazines has been researched along with bay 11-7082 in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (71.43)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ford, RJ; Lo, P; Pham, LV; Tamayo, AT; Yoshimura, LC1
Benet, I; García-Conde, J; Jantus-Lewintre, E; Sarsotti, E; Terol, MJ1
Allen, P; Higginbottom, K; Joel, SP; Jüliger, S; Lister, TA; Maharaj, L; Schenkein, D; Strauss, SJ1
Barbone, D; Darnowski, JW; Fennell, DA; Galvani, A; Gasparri, F; Gaudino, G; Mutti, L; Nici, L; Porta, C; Sartore-Bianchi, A1
Albanell, J; Belda-Iniesta, C; Cejas, P; Chattopadhyay, S; Cortes-Sempere, M; de Castro-Carpeño, J; Gonzalez-Barón, M; Machado-Pinilla, R; Manguan-García, C; Moratilla, C; Nistal, M; Perona, R; Rodriguez-Fanjul, V; Rovira, A; Sánchez-Pérez, I; Tapia, M1
Bronson, R; Feldser, DM; Jacks, T; Meylan, E; Oliver, TG; Winslow, MM; Xue, W1
Cho, NH; Choi, HK; Chun, YJ; Im, HJ; Kim, D; Kwon, Y; Park, N; Park, YS; Shin, S; Sung, CH; Ye, DJ1

Other Studies

7 other study(ies) available for pyrazines and bay 11-7082

ArticleYear
Inhibition of constitutive NF-kappa B activation in mantle cell lymphoma B cells leads to induction of cell cycle arrest and apoptosis.
    Journal of immunology (Baltimore, Md. : 1950), 2003, Jul-01, Volume: 171, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; B-Lymphocyte Subsets; bcl-X Protein; Biopsy; Boronic Acids; Bortezomib; Cell Cycle; Growth Inhibitors; Humans; Hydrolysis; I-kappa B Proteins; Lymphoma, B-Cell; Lymphoma, Mantle-Cell; Minor Histocompatibility Antigens; NF-kappa B; NF-KappaB Inhibitor alpha; Nitriles; Organic Chemicals; Proto-Oncogene Proteins c-bcl-2; Pyrazines; Sulfones; Tumor Cells, Cultured

2003
Bortezomib induces different apoptotic rates in B-CLL cells according to IgVH and BCL-6 mutations.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2006, Volume: 8, Issue:11

    Topics: ADP-ribosyl Cyclase 1; Adult; Aged; Aged, 80 and over; Amino Acid Chloromethyl Ketones; Antineoplastic Agents; Apoptosis; Boronic Acids; Bortezomib; Caspase Inhibitors; Caspases; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Gene Rearrangement, B-Lymphocyte, Heavy Chain; Genes, Immunoglobulin; Humans; I-kappa B Kinase; I-kappa B Proteins; Immunoglobulin Heavy Chains; Immunoglobulin Variable Region; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Neoplasm Proteins; NF-kappa B; Nitriles; Phosphorylation; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-bcl-6; Pyrazines; Sulfones; Tumor Cells, Cultured; ZAP-70 Protein-Tyrosine Kinase

2006
The proteasome inhibitor bortezomib acts independently of p53 and induces cell death via apoptosis and mitotic catastrophe in B-cell lymphoma cell lines.
    Cancer research, 2007, Mar-15, Volume: 67, Issue:6

    Topics: Antineoplastic Agents; Apoptosis; Boronic Acids; Bortezomib; Caspases; Cell Cycle Proteins; Cell Line, Tumor; Enzyme Activation; Humans; Lymphoma, B-Cell; Mitosis; NF-kappa B; Nitriles; Protease Inhibitors; Proto-Oncogene Proteins c-bcl-2; Pyrazines; Sulfones; Tumor Suppressor Protein p53

2007
Bortezomib inhibits nuclear factor-kappaB dependent survival and has potent in vivo activity in mesothelioma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Oct-01, Volume: 13, Issue:19

    Topics: Animals; Antineoplastic Agents; Boronic Acids; Bortezomib; Cell Line, Tumor; Cell Survival; Cell Transformation, Neoplastic; Enzyme Inhibitors; Humans; Male; Mesothelioma; Mice; Mice, Nude; NF-kappa B; Nitriles; Proteasome Inhibitors; Pyrazines; Sulfones; Tumor Necrosis Factor-alpha

2007
MKP1 repression is required for the chemosensitizing effects of NF-kappaB and PI3K inhibitors to cisplatin in non-small cell lung cancer.
    Cancer letters, 2009, Dec-28, Volume: 286, Issue:2

    Topics: Antineoplastic Agents; Blotting, Western; Boronic Acids; Bortezomib; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; Chromones; Cisplatin; Dual Specificity Phosphatase 1; Humans; Immunohistochemistry; JNK Mitogen-Activated Protein Kinases; Lung Neoplasms; Morpholines; NF-kappa B; Nitriles; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyrazines; RNA Interference; Signal Transduction; Sulfones

2009
Response and resistance to NF-κB inhibitors in mouse models of lung adenocarcinoma.
    Cancer discovery, 2011, Volume: 1, Issue:3

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Antineoplastic Agents; Boronic Acids; Bortezomib; Cell Line, Tumor; Drug Resistance, Neoplasm; Lung Neoplasms; Mice; Mice, 129 Strain; NF-kappa B; Nitriles; Pyrazines; Signal Transduction; Sulfones; Survival Rate; Transcription Factor RelA

2011
Induction of steroid sulfatase expression in PC-3 human prostate cancer cells by insulin-like growth factor II.
    Toxicology letters, 2013, Nov-25, Volume: 223, Issue:2

    Topics: 17-Hydroxysteroid Dehydrogenases; Androstadienes; Boronic Acids; Bortezomib; Cell Line, Tumor; Chromones; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Humans; Insulin-Like Growth Factor II; Leupeptins; Male; Morpholines; NF-kappa B; Nitriles; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Polymerase Chain Reaction; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Pyrazines; Sequence Analysis, DNA; Signal Transduction; Steryl-Sulfatase; Sulfones; Sulfotransferases; Wortmannin

2013