Page last updated: 2024-08-21

pyrazines and atorvastatin

pyrazines has been researched along with atorvastatin in 4 studies

Research

Studies (4)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (25.00)	29.6817
2010's	3 (75.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Kurbanov, RD; Shek, AB; Tashkenbaeva, NF	1
Bhome, R; Penn, H	1
Scheen, AJ	1
Aquilante, CL; Kosmiski, LA; Predhomme, JA; Sidhom, MS; Wempe, MF	1

Reviews

1 review(s) available for pyrazines and atorvastatin

Article	Year
Pharmacokinetic evaluation of atorvastatin and sitagliptin in combination for the treatment of type 2 diabetes. Expert opinion on drug metabolism & toxicology, 2012, Volume: 8, Issue:6 Topics: Atorvastatin; Blood Glucose; Cardiovascular Diseases; Cholesterol; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Pyrazines; Pyrroles; Risk Assessment; Sitagliptin Phosphate; Treatment Outcome; Triazoles	2012

Article

Year

Pharmacokinetic evaluation of atorvastatin and sitagliptin in combination for the treatment of type 2 diabetes.

Expert opinion on drug metabolism & toxicology, 2012, Volume: 8, Issue:6

Topics: Atorvastatin; Blood Glucose; Cardiovascular Diseases; Cholesterol; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Pyrazines; Pyrroles; Risk Assessment; Sitagliptin Phosphate; Treatment Outcome; Triazoles

2012

Trials

2 trial(s) available for pyrazines and atorvastatin

Article	Year
[Effects of atorvastatin and acipimox on the lipid spectrum of blood plasma, endothelial function and a clinical course of unstable angina pectoris]. Terapevticheskii arkhiv, 2006, Volume: 78, Issue:8 Topics: Angina, Unstable; Atorvastatin; Brachial Artery; Cholesterol, LDL; Drug Therapy, Combination; Endothelium, Vascular; Follow-Up Studies; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Male; Pyrazines; Pyrroles; Treatment Outcome; Vasodilation	2006
Effect of ABCB1 polymorphisms and atorvastatin on sitagliptin pharmacokinetics in healthy volunteers. European journal of clinical pharmacology, 2013, Volume: 69, Issue:7 Topics: Adult; Atorvastatin; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biotransformation; Cohort Studies; Colorado; Cross-Over Studies; Dipeptidyl-Peptidase IV Inhibitors; Drug Interactions; Female; Genetic Association Studies; Half-Life; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Metabolic Clearance Rate; Middle Aged; Polymorphism, Single Nucleotide; Pyrazines; Pyrroles; Sitagliptin Phosphate; Triazoles; Young Adult	2013

Article

Year

[Effects of atorvastatin and acipimox on the lipid spectrum of blood plasma, endothelial function and a clinical course of unstable angina pectoris].

Terapevticheskii arkhiv, 2006, Volume: 78, Issue:8

Topics: Angina, Unstable; Atorvastatin; Brachial Artery; Cholesterol, LDL; Drug Therapy, Combination; Endothelium, Vascular; Follow-Up Studies; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Male; Pyrazines; Pyrroles; Treatment Outcome; Vasodilation

2006

Effect of ABCB1 polymorphisms and atorvastatin on sitagliptin pharmacokinetics in healthy volunteers.

European journal of clinical pharmacology, 2013, Volume: 69, Issue:7

Topics: Adult; Atorvastatin; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biotransformation; Cohort Studies; Colorado; Cross-Over Studies; Dipeptidyl-Peptidase IV Inhibitors; Drug Interactions; Female; Genetic Association Studies; Half-Life; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Metabolic Clearance Rate; Middle Aged; Polymorphism, Single Nucleotide; Pyrazines; Pyrroles; Sitagliptin Phosphate; Triazoles; Young Adult

2013

Other Studies

1 other study(ies) available for pyrazines and atorvastatin

Article	Year
Rhabdomyolysis precipitated by a sitagliptin-atorvastatin drug interaction. Diabetic medicine : a journal of the British Diabetic Association, 2012, Volume: 29, Issue:5 Topics: Aged; Atorvastatin; Drug Interactions; Drug Therapy, Combination; Heptanoic Acids; Humans; Male; Pyrazines; Pyrroles; Rhabdomyolysis; Sitagliptin Phosphate; Treatment Outcome; Triazoles	2012