pyrazines has been researched along with allopurinol in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (30.77) | 18.7374 |
| 1990's | 9 (34.62) | 18.2507 |
| 2000's | 6 (23.08) | 29.6817 |
| 2010's | 2 (7.69) | 24.3611 |
| 2020's | 1 (3.85) | 2.80 |
| Authors | Studies |
|---|---|
| Fanelli, GM; Weiner, IM | 2 |
| Gotoh, N; Niki, E | 1 |
| Koga, S; Nakano, M | 1 |
| Nakano, M | 1 |
| Goto, T; Nakano, M; Sugioka, K; Ushijima, Y | 1 |
| Furumoto, S; Mitsuda, H; Suzuki, Y | 1 |
| Haddow, A; Ross, WC; Timmis, GM | 1 |
| Bloch, A; Bobek, M; Cole, FE; Sharma, RA | 1 |
| Tinker, JP; Weiner, IM | 1 |
| Aroldi, A; Colussi, G; D'Angelo, A; Fabris, A; Graziani, G; Mandressi, A; Maschio, G; Minetti, L; Pagano, F; Ponticelli, C; Rocco, F; Surian, M; Tasca, A; Tessitore, N; Trinchieri, A | 1 |
| Nagamine, T; Sekiguchi, T | 1 |
| Huang, CK; Maruyama, N; Nakano, M; Uehara, K | 1 |
| Itoh, T; Kamisaki, Y; Nakamoto, K; Wada, K | 1 |
| Shimomura, O; Teranishi, K | 1 |
| Kawanaka, N; Nakamura, Y; Sato, M; Tsutsui, Y; Yamaguchi, S | 1 |
| Freeman, BA; Radi, R; Richardson, G; Suarez, E; Tarpey, MM; White, CR | 1 |
| Crause, P; Gloe, T; Keller, M; Pohl, U; Sohn, HY | 1 |
| Anastacio, VM; Augusto, O; da Luz, PL; Junqueira, ML; Krieger, JE; Laurindo, FR; Pereira, AC; Souza, HP; Souza, LC | 1 |
| Cheng, W; Hisadome, K; Ito, Y; Karashima, Y; Kimura, C; Koyama, T; Oike, M; Wang, YP | 1 |
| Finel, M; Hassinen, IE; Kervinen, M; Pätsi, J | 1 |
| Moffett, JW; Rose, AL; Waite, TD | 1 |
| Akatov, VS; Fisyuk, AS; Kruglov, AG; Nikiforova, AB; Shatalin, YV; Shubina, VV | 1 |
| Bhalodia, Y; Manek, R; Sheth, N; Vaghasiya, J | 1 |
| Li, D; Lin, LN; Wang, WT; Xu, ZJ | 1 |
| Abe, T; Anzai, N; Mishima, E; Miyazaki, M | 1 |
1 review(s) available for pyrazines and allopurinol
| Article | Year |
|---|---|
Uric Acid Elevation by Favipiravir, an Antiviral Drug.
Topics: Aldehyde Oxidase; Amides; Antiviral Agents; Biotransformation; Coronavirus Infections; COVID-19; Drug Interactions; Humans; Hyperuricemia; Kidney; Kidney Diseases; Molecular Structure; Organic Anion Transport Protein 1; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Organic Cation Transport Proteins; Pandemics; Pneumonia, Viral; Pyrazines; Uric Acid; Xanthine Oxidase | 2020 |
25 other study(ies) available for pyrazines and allopurinol
| Article | Year |
|---|---|
Renal urate excretion in animal models.
Topics: Allopurinol; Animals; Carboxylic Acids; Dogs; Goats; Haplorhini; Humans; Kidney; Kidney Tubules, Proximal; Male; Mersalyl; Pan troglodytes; Probenecid; Pyrazines; Uric Acid | 1975 |
Rates of interactions of superoxide with vitamin E, vitamin C and related compounds as measured by chemiluminescence.
Topics: Ascorbic Acid; Binding, Competitive; Chromans; Hydrogen-Ion Concentration; Hypoxanthine; Hypoxanthines; Kinetics; Liposomes; Luminescent Measurements; Phosphatidylcholines; Pyrazines; Superoxides; Vitamin E; Xanthine Oxidase | 1992 |
A high involvement of O2- possibly generated in inner membranes for iron-induced microsomal lipid peroxidation.
Topics: Animals; Ceruloplasmin; Copper; Cytochrome P-450 Enzyme System; Erythrocytes; Free Radical Scavengers; Imidazoles; Intracellular Membranes; Iron; Lipid Peroxidation; Luminescent Measurements; Microsomes, Liver; Milk; Models, Biological; Organometallic Compounds; Pyrazines; Rats; Salicylates; Superoxide Dismutase; Superoxides; Xanthine Oxidase | 1992 |
Assay for superoxide dismutase based on chemiluminescence of luciferin analog.
Topics: Animals; Erythrocytes; Granulocytes; Humans; Imidazoles; Indicators and Reagents; Isoenzymes; Luminescent Measurements; Lymphocytes; Organ Specificity; Pyrazines; Rats; Superoxide Dismutase; Xanthine Oxidase | 1990 |
Chemiluminescence probe with Cypridina luciferin analog, 2-methyl-6-phenyl-3,7-dihydroimidazo[1,2-a]pyrazin-3-one, for estimating the ability of human granulocytes to generate O2-.
Topics: Granulocytes; Humans; Hydrogen Peroxide; Luminescent Measurements; Peroxidase; Phagocytosis; Pyrazines; Superoxides; Xanthine Oxidase; Zymosan | 1986 |
An extreme diminution in the strong affinity of 2-amino-4-hydroxy-6-formylpteridine for xanthine oxidase by reduction of a 7, 8-double bond or a formyl group at position 6 of its pyrazine ring.
Topics: Amines; Animals; Binding Sites; Binding, Competitive; Kinetics; Mathematics; Milk; Models, Chemical; Oxidation-Reduction; Polarography; Pteridines; Pyrazines; Structure-Activity Relationship; Xanthine Oxidase; Xanthines | 1974 |
The chain of unexpected discovery: xanthopterin-stimulated renal mitosis.
Topics: Animals; Biochemistry; Creativity; History, 20th Century; Hyperplasia; Hypertrophy; Hypoxanthines; Kidney; Kidney Diseases; Mitosis; Pteridines; Purines; Pyrazines; Pyrimidines; Quinoxalines; Rats; Stimulation, Chemical; Structure-Activity Relationship; United Kingdom; Xanthine Oxidase; Xanthopterin | 1972 |
Synthesis and biological activity of some imidazo(4,5-b)pyrazines and their ribonucleosides as purine analogs.
Topics: Animals; Burkitt Lymphoma; Cells; Cells, Cultured; Crystallography; Escherichia coli; Imidazoles; Inosine; Leukemia L1210; Mammary Neoplasms, Experimental; Methods; Mice; Oxides; Purines; Pyrazines; Ribonucleosides; Xanthine Oxidase | 1973 |
Pharmacology of pyrazinamide: metabolic and renal function studies related to the mechanism of drug-induced urate retention.
Topics: Adsorption; Allopurinol; Animals; Biological Transport, Active; Biotransformation; Carboxylic Acids; Colorimetry; Dogs; Female; Filtration; Haplorhini; Humans; Inulin; Kidney; Kidney Function Tests; Kidney Tubules; Male; Metabolism; Pyrazinamide; Pyrazines; Uric Acid; Uricosuric Agents | 1972 |
Pyrazinoate excretion in the chimpanzee. Relation to urate disposition and the actions of uricosuric drugs.
Topics: Allopurinol; Aminohippuric Acids; Animals; Biological Transport; Carboxylic Acids; Chlorothiazide; Depression, Chemical; Glomerular Filtration Rate; Insulin; Iodopyracet; Kidney Tubules; Male; Organomercury Compounds; Pan troglodytes; Probenecid; Protein Binding; Pyrazines; Salicylates; Stimulation, Chemical; Sulfinpyrazone; Uric Acid; Uricosuric Agents | 1973 |
Prevention of calcium nephrolithiasis with low-dose thiazide, amiloride and allopurinol.
Topics: Adult; Allopurinol; Amiloride; Calcium; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Kidney Calculi; Male; Middle Aged; Pyrazines; Uric Acid | 1981 |
Inhibition of free radical generation by biotin.
Topics: Adult; Biotin; Cytochrome c Group; Free Radicals; Humans; Hypoxanthine; Hypoxanthines; Luminescent Measurements; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pyrazines; Spectrophotometry; Xanthine Oxidase | 1994 |
The first application of a chemiluminescence probe, 2-methyl-6-[p-methoxyphenyl]-3,7-dihydroimidazo[1,2-a]pyrazin-3-one (MCLA), for detecting O2- production, in vitro, from Kupffer cells stimulated by phorbol myristate acetate.
Topics: Animals; Hypoxanthine; Hypoxanthines; Imidazoles; In Vitro Techniques; Kupffer Cells; Luminescent Measurements; Male; Pyrazines; Rats; Rats, Wistar; Superoxides; Tetradecanoylphorbol Acetate; Xanthine Oxidase | 1993 |
Effect of cystathionine as a scavenger of superoxide generated from human leukocytes or derived from xanthine oxidase in vitro.
Topics: Cystathionine; Erythrocyte Membrane; Free Radical Scavengers; Humans; Hydroxyl Radical; Imidazoles; Leukocytes; Lipid Peroxidation; Pyrazines; Superoxides; Xanthine Oxidase | 1996 |
Coelenterazine analogs as chemiluminescent probe for superoxide anion.
Topics: Aequorin; Firefly Luciferin; Hypoxanthine; Imidazoles; Luminescent Measurements; Molecular Structure; Pyrazines; Sensitivity and Specificity; Solubility; Structure-Activity Relationship; Superoxides; Xanthine Oxidase | 1997 |
Effects of zinc acexamate (NAS-501) on superoxide radicals and lipid peroxidation of rat gastric mucosa.
Topics: Aminocaproates; Aminocaproic Acid; Animals; Anti-Ulcer Agents; Antioxidants; Electron Spin Resonance Spectroscopy; Gastric Mucosa; Guinea Pigs; Hypoxanthine; Lipid Peroxidation; Luminescent Measurements; Macrophages; Male; Neutrophils; Pyrazines; Rats; Rats, Sprague-Dawley; Superoxides; Thiobarbituric Acid Reactive Substances; Xanthine Oxidase | 1999 |
Chemiluminescent detection of oxidants in vascular tissue. Lucigenin but not coelenterazine enhances superoxide formation.
Topics: Acetylcholine; Acridines; Animals; Cells, Cultured; Cytochrome c Group; Endothelium, Vascular; Firefly Luciferin; Hydrogen Peroxide; Imidazoles; Luminescent Measurements; Male; NAD; Nitrates; Oxidants; Oxygen Consumption; Pyrazines; Rats; Rats, Sprague-Dawley; Superoxides; Vasodilator Agents; Xanthine Oxidase | 1999 |
Pitfalls of using lucigenin in endothelial cells: implications for NAD(P)H dependent superoxide formation.
Topics: Acridines; Arsenicals; Cells, Cultured; Cytochrome c Group; Imidazoles; Luminescent Measurements; NAD; NADH, NADPH Oxidoreductases; NADP; NADPH Oxidases; Neutrophils; Onium Compounds; Pyrazines; Superoxides; Umbilical Veins; Xanthine; Xanthine Oxidase | 2000 |
Vascular oxidant stress early after balloon injury: evidence for increased NAD(P)H oxidoreductase activity.
Topics: Acridines; Animals; Biphenyl Compounds; Catheterization; Cyclic N-Oxides; Cyclooxygenase Inhibitors; Electron Spin Resonance Spectroscopy; Electron Transport; Endothelium, Vascular; Free Radicals; Glutathione; Imidazoles; Lipoxygenase Inhibitors; Luminescent Measurements; Male; Metalloporphyrins; NAD; NADH, NADPH Oxidoreductases; NADP; NADPH Oxidases; NF-kappa B; Nitric Oxide Synthase; Onium Compounds; Oxidation-Reduction; Oxidative Stress; Oxygen Consumption; Pyrazines; Rabbits; Reactive Oxygen Species; Recombinant Fusion Proteins; Spin Labels; Superoxide Dismutase; Superoxides; Transcription, Genetic; Wound Healing; Xanthine Oxidase | 2000 |
Superoxide anion impairs contractility in cultured aortic smooth muscle cells.
Topics: Adenosine Triphosphate; Animals; Aorta, Thoracic; Calcium; Cattle; Cells, Cultured; Collagen; Enzyme Inhibitors; Gels; Imidazoles; Intracellular Fluid; Ionophores; Luminescent Measurements; Muscle, Smooth, Vascular; Potassium; Pyrazines; Superoxide Dismutase; Superoxides; Vasoconstriction; Xanthine; Xanthine Oxidase | 2002 |
Lucigenin and coelenterazine as superoxide probes in mitochondrial and bacterial membranes.
Topics: Acridines; Animals; Cell Membrane; Firefly Luciferin; Hypoxanthine; Imidazoles; Intracellular Membranes; Luminescent Measurements; Mitochondria, Liver; Molecular Probes; NADH, NADPH Oxidoreductases; Oxidation-Reduction; Paracoccus denitrificans; Pyrazines; Rats; Superoxides; Time Factors; Xanthine Oxidase | 2004 |
Determination of superoxide in seawater using 2-methyl-6-(4-methoxyphenyl)-3,7- dihydroimidazo[1,2-a]pyrazin-3(7H)-one chemiluminescence.
Topics: Hydrogen-Ion Concentration; Imidazoles; Luminescence; Luminescent Measurements; Metals; Oxygen; Pacific Ocean; Photochemistry; Pyrazines; Seawater; Superoxides; Time Factors; Xanthine; Xanthine Oxidase | 2008 |
Sulfur-containing compounds quench 3,7-dihydro-2-methyl-6-(4-methoxyphenyl)imidazol[1,2-a]pyrazine-3-one chemiluminescence: Discrimination between true antioxidants and quenchers using xanthine oxidase.
Topics: Antioxidants; Imidazoles; Luminescent Measurements; Pyrazines; Sulfur Compounds; Xanthine Oxidase | 2010 |
Sitagliptin protects renal ischemia reperfusion induced renal damage in diabetes.
Topics: Animals; Apoptosis; Catalase; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; DNA Fragmentation; Female; Glutathione; Glutathione Peroxidase; Kidney; Kidney Diseases; Lipid Peroxidation; Male; Oxidative Stress; Peroxidase; Pyrazines; Rats; Rats, Wistar; Reperfusion Injury; Sitagliptin Phosphate; Superoxide Dismutase; Triazoles; Xanthine Oxidase | 2011 |
[Effects of ligustrazin on lipid peroxidation during hepatic ischemia reperfusion injury].
Topics: Alanine Transaminase; Animals; Female; Lipid Peroxidation; Liver; Male; Malondialdehyde; Pyrazines; Rabbits; Reperfusion Injury; Superoxide Dismutase; Xanthine Oxidase | 2002 |