pyrazines has been researched along with 2-aminopyrazine in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 8 (66.67) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Lunn, WH; Shadle, JK | 1 |
| Burton, M; Cavalier, JF; Dussart, F; Marchand, C; Marchand-Brynaert, J; Rees, JF | 1 |
| Asiri, AM; Badahdah, KO | 1 |
| De Wael, F; Lambert, DM; Marchand-Brynaert, J; Muccioli, GG; Rees, JF; Schneider, YJ; Sergent, T | 1 |
| Aleskog, A; Ekholm, C; Eriksson, A; Fhölenhag, K; Hassan, SB; Höglund, M; Jensen, AJ; Larsson, R; Lindhagen, E; Löthgren, A; Parrow, V; Scobie, M | 1 |
| Hammarström, LG; Lundbäck, T; Rottenberg, ME; Sjöberg, B; Svensson, R; Vodnala, SK | 1 |
| Chai, S; Cong, SL; Han, YC; Yu, J | 1 |
| Chapman, K; Cubbon, RM; Hale, JJ; Lin, S; Lombardo, M; Malkani, S; Mills, SG; O'Neill, EA; Thompson, JE; Wang, R; Yang, L; Zhang, WX | 1 |
| Banks, MD; Bennett, RV; Fernández, FM; Kaddi, CD; Paine, MR; Wang, MD; Weber, AL | 1 |
| Angulo-Barturen, I; Antonova-Koch, Y; Bashyam, S; Birkholtz, LM; Botha, ME; Charman, SA; Chibale, K; Ferrer, S; Gonzàlez Cabrera, D; Han, Z; Jiménez-Díaz, MB; Lawrence, N; Le Manach, C; Martínez, MS; Meister, S; Nchinda, AT; Nondaba, SH; Paquet, T; Reader, J; Street, LJ; Taylor, D; Waterson, D; White, KL; Winzeler, EA; Wittlin, S; Witty, MJ; Younis, Y; Zabiulla, M | 1 |
| Abdildinova, A; Gong, YD; Yang, SJ | 1 |
| Arista, L; Broennimann, V; Guth, S; Head, V; Kramer, I; Stiefl, N; Teixeira-Fouchard, S; Ullrich, T; Weiler, S | 1 |
12 other study(ies) available for pyrazines and 2-aminopyrazine
| Article | Year |
|---|---|
Mercapturic acid formation from 2-aminopyrazine in rats.
Topics: Acetylcysteine; Animals; Chromatography, High Pressure Liquid; Mass Spectrometry; Pyrazines; Rats; Rats, Zucker | 1992 |
Catechol derivatives of aminopyrazine and cell protection against UVB-induced mortality.
Topics: Antioxidants; Catechols; Cell Line; Culture Media; Humans; L-Lactate Dehydrogenase; NAD; Pyrazines; Radiation-Protective Agents; Ultraviolet Rays | 2001 |
Synthesis of some new anils: part 1. Reaction of 2-hydroxy-benzaldehyde and 2-hydroxynaphthaldehyde with 2-aminopyridene and 2-aminopyrazine.
Topics: Acetonitriles; Aldehydes; Aminopyridines; Aniline Compounds; Magnetic Resonance Spectroscopy; Naphthalenes; Pyrazines; Schiff Bases; Solvents; Spectrophotometry, Infrared; Stereoisomerism; Toluene | 2007 |
Chemistry around imidazopyrazine and ibuprofen: discovery of novel fatty acid amide hydrolase (FAAH) inhibitors.
Topics: Aldehydes; Amidohydrolases; Anti-Inflammatory Agents; Antioxidants; Caco-2 Cells; Cannabinoid Receptor Modulators; Drug Discovery; Enzyme Inhibitors; Humans; Ibuprofen; Oximes; Pyrazines; Pyrazoles | 2010 |
Identification of AKN-032, a novel 2-aminopyrazine tyrosine kinase inhibitor, with significant preclinical activity in acute myeloid leukemia.
Topics: Adult; Aged; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Epithelial Cells; Female; Flow Cytometry; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myelomonocytic, Acute; Male; Mice; Middle Aged; Molecular Structure; Pyrazines; Xenograft Model Antitumor Assays; Young Adult | 2010 |
In vitro and in vivo activities of 2-aminopyrazines and 2-aminopyridines in experimental models of human African trypanosomiasis.
Topics: Aminopyridines; Animals; Benzopyrans; Cell Line; Humans; Mice; Mice, Inbred C57BL; Piperidines; Pyrazines; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma brucei gambiense; Trypanosoma brucei rhodesiense; Trypanosomiasis, African | 2013 |
Multiple hydrogen bonding in excited states of aminopyrazine in methanol solution: time-dependent density functional theory study.
Topics: Computer Simulation; Electrons; Fluorescence; Hydrogen Bonding; Light; Methanol; Models, Molecular; Molecular Conformation; Pyrazines; Quantum Theory; Solutions; Thermodynamics; Time Factors | 2013 |
Design, synthesis, and biological evaluation of aminopyrazine derivatives as inhibitors of mitogen-activated protein kinase-activated protein kinase 2 (MK-2).
Topics: Cell Line; Drug Design; Enzyme Activation; Humans; Inhibitory Concentration 50; Mitogen-Activated Protein Kinase 1; Molecular Structure; Pyrazines | 2015 |
DetectTLC: Automated Reaction Mixture Screening Utilizing Quantitative Mass Spectrometry Image Features.
Topics: Chromatography, Thin Layer; Complex Mixtures; Data Mining; Fluorescence; Image Processing, Computer-Assisted; Mass Spectrometry; Pyrazines | 2016 |
Identification of a Potential Antimalarial Drug Candidate from a Series of 2-Aminopyrazines by Optimization of Aqueous Solubility and Potency across the Parasite Life Cycle.
Topics: Animals; Antimalarials; Disease Models, Animal; Dose-Response Relationship, Drug; Ether-A-Go-Go Potassium Channels; Hep G2 Cells; Humans; Life Cycle Stages; Malaria; Mice; Mice, SCID; Microsomes, Liver; Molecular Structure; Parasitic Diseases, Animal; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Pyrazines; Solubility; Structure-Activity Relationship; Water | 2016 |
Solid-Phase Parallel Synthesis of N-Substituted-2-aminothiazolo[4,5-b]pyrazine Derivatives via Tandem Reaction of Isothiocyanate Terminated Resin with o-Bromo-2-Aminopyrazines.
Topics: Cyclization; Isothiocyanates; Molecular Docking Simulation; Molecular Structure; Pyrazines; Solid-Phase Synthesis Techniques; Thiazoles | 2016 |
Discovery of a novel 2-aminopyrazine-3-carboxamide as a potent and selective inhibitor of Activin Receptor-Like Kinase-2 (ALK2) for the treatment of fibrodysplasia ossificans progressiva.
Topics: Activin Receptors, Type I; Humans; Myositis Ossificans; Ossification, Heterotopic; Pyrazines; Signal Transduction | 2022 |