Compounds > pyrazines
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pyrazines and 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one

pyrazines has been researched along with 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (30.00)29.6817
2010's5 (50.00)24.3611
2020's2 (20.00)2.80

Authors

AuthorsStudies
Mao, H; Schnellmann, RG; Xing, J; Zhang, Z; Zhuang, S1
Chen, KF; Chen, PJ; Cheng, AL; Hsieh, HP; Hsu, C; Hsu, CH; Lu, YS; Yeh, PY1
Albanell, J; Belda-Iniesta, C; Cejas, P; Chattopadhyay, S; Cortes-Sempere, M; de Castro-Carpeño, J; Gonzalez-Barón, M; Machado-Pinilla, R; Manguan-García, C; Moratilla, C; Nistal, M; Perona, R; Rodriguez-Fanjul, V; Rovira, A; Sánchez-Pérez, I; Tapia, M1
Abal, L; Casanova, JM; Dolcet, X; Egido, R; Llombart-Cussac, A; Martí, RM; Matias-Guiu, X; Moreno, S; Puig, S; Santacana, M; Sorolla, A; Valls, J; Velasco, A; Vilella, R; Yeramian, A1
Cho, NH; Choi, HK; Chun, YJ; Im, HJ; Kim, D; Kwon, Y; Park, N; Park, YS; Shin, S; Sung, CH; Ye, DJ1
Bogachkov, Y; Doscas, ME; Kaufman, H; Li, Y; Rao, GS; Ruby, C; Usha, L; Wang, Y; Williams, JW; Williamson, AJ; Xiao, F; Xu, X; Zhou, J1
Li, W; Wang, C; Wang, P; Zeng, W1
Ding, JD; Ma, GS; Sheng, ZL; Wang, X; Zuo, PF; Zuo, Z1
Guo, Z; He, S; Hu, Z; Jiang, K; Lin, C; Su, H; Yuan, G; Zeng, Y; Zhong, F1
Chen, Q; Gao, W; Ge, J; Liu, B; Liu, J; Tang, D; Yang, J; Zhao, J1

Other Studies

10 other study(ies) available for pyrazines and 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one

ArticleYear
Src regulates cell cycle protein expression and renal epithelial cell proliferation via PI3K/Akt signaling-dependent and -independent mechanisms.
    American journal of physiology. Renal physiology, 2008, Volume: 295, Issue:1

    Topics: Cell Line; Cell Proliferation; Chromones; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinase Inhibitor p57; Epithelial Cells; Hydrazines; Kidney; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Morpholines; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Pyrazines; Quinolines; Signal Transduction; src-Family Kinases; Up-Regulation

2008
Bortezomib overcomes tumor necrosis factor-related apoptosis-inducing ligand resistance in hepatocellular carcinoma cells in part through the inhibition of the phosphatidylinositol 3-kinase/Akt pathway.
    The Journal of biological chemistry, 2009, Apr-24, Volume: 284, Issue:17

    Topics: Antineoplastic Agents; Apoptosis; Boronic Acids; Bortezomib; Carcinoma, Hepatocellular; Cell Line, Tumor; Chromones; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Liver Neoplasms; Morpholines; NF-kappa B; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyrazines; RNA, Small Interfering; TNF-Related Apoptosis-Inducing Ligand

2009
MKP1 repression is required for the chemosensitizing effects of NF-kappaB and PI3K inhibitors to cisplatin in non-small cell lung cancer.
    Cancer letters, 2009, Dec-28, Volume: 286, Issue:2

    Topics: Antineoplastic Agents; Blotting, Western; Boronic Acids; Bortezomib; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; Chromones; Cisplatin; Dual Specificity Phosphatase 1; Humans; Immunohistochemistry; JNK Mitogen-Activated Protein Kinases; Lung Neoplasms; Morpholines; NF-kappa B; Nitriles; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyrazines; RNA Interference; Signal Transduction; Sulfones

2009
Inhibition of activated receptor tyrosine kinases by Sunitinib induces growth arrest and sensitizes melanoma cells to Bortezomib by blocking Akt pathway.
    International journal of cancer, 2012, Feb-15, Volume: 130, Issue:4

    Topics: Antineoplastic Agents; Boronic Acids; Bortezomib; Cell Line, Tumor; Cell Proliferation; Chromones; Humans; Indoles; Melanoma; Morpholines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyrazines; Pyrroles; Receptor Protein-Tyrosine Kinases; Receptor, Platelet-Derived Growth Factor alpha; RNA, Small Interfering; Signal Transduction; Sunitinib; Vascular Endothelial Growth Factor Receptor-2

2012
Induction of steroid sulfatase expression in PC-3 human prostate cancer cells by insulin-like growth factor II.
    Toxicology letters, 2013, Nov-25, Volume: 223, Issue:2

    Topics: 17-Hydroxysteroid Dehydrogenases; Androstadienes; Boronic Acids; Bortezomib; Cell Line, Tumor; Chromones; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Humans; Insulin-Like Growth Factor II; Leupeptins; Male; Morpholines; NF-kappa B; Nitriles; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Polymerase Chain Reaction; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Pyrazines; Sequence Analysis, DNA; Signal Transduction; Steryl-Sulfatase; Sulfones; Sulfotransferases; Wortmannin

2013
Inhibition of p70 S6 kinase (S6K1) activity by A77 1726 and its effect on cell proliferation and cell cycle progress.
    Neoplasia (New York, N.Y.), 2014, Volume: 16, Issue:10

    Topics: Aniline Compounds; Butadienes; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Chromones; Crotonates; Feedback, Physiological; Gene Knockdown Techniques; Humans; Hydroxybutyrates; Imidazoles; Isoxazoles; Leflunomide; MAP Kinase Signaling System; Morpholines; Nitriles; Phosphatidylinositol 3-Kinases; Protein Kinase Inhibitors; Pyrazines; Receptor, IGF Type 1; Ribosomal Protein S6 Kinases, 70-kDa; Toluidines

2014
Tetramethylpyrazine improves the recovery of spinal cord injury via Akt/Nrf2/HO-1 pathway.
    Bioorganic & medicinal chemistry letters, 2016, Feb-15, Volume: 26, Issue:4

    Topics: Animals; Apoptosis; Caspase 3; Chromones; Cytokines; Heme Oxygenase-1; Locomotion; Male; Morpholines; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidative Stress; Phosphorylation; Protein Binding; Proto-Oncogene Proteins c-akt; Pyrazines; Rats; Rats, Sprague-Dawley; Signal Transduction; Spinal Cord Injuries

2016
Tetramethylprazine attenuates myocardial ischemia/reperfusion injury through modulation of autophagy.
    Life sciences, 2019, Dec-15, Volume: 239

    Topics: Animals; Apoptosis; Autophagy; Cardiotonic Agents; Cell Survival; Chromones; Creatine Kinase; L-Lactate Dehydrogenase; Male; Morpholines; Myocardial Reperfusion Injury; Myocytes, Cardiac; Primary Cell Culture; Protein Kinase Inhibitors; Pyrazines; Rats; Rats, Sprague-Dawley

2019
Tetramethylpyrazine ameliorates hepatic fibrosis through autophagy-mediated inflammation.
    Biochemistry and cell biology = Biochimie et biologie cellulaire, 2020, Volume: 98, Issue:3

    Topics: Animals; Autophagy; Carbon Tetrachloride; Cell Line, Tumor; Chromones; Chronic Disease; Fibrinolytic Agents; Hepatic Stellate Cells; Inflammation; Liver Cirrhosis; Male; Microscopy, Fluorescence; Morpholines; Phosphatidylinositol 3-Kinases; Platelet-Derived Growth Factor; Pyrazines; Rats; Rats, Sprague-Dawley; Signal Transduction

2020
miR‑181d promotes cell proliferation via the IGF1/PI3K/AKT axis in glioma.
    Molecular medicine reports, 2020, Volume: 22, Issue:5

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Chromones; Glioma; Humans; Imidazoles; Insulin-Like Growth Factor I; Male; Mice; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyrazines; Signal Transduction; Transfection; Tumor Burden; Xenograft Model Antitumor Assays

2020