pyrazinamide has been researched along with isoniazid in 1868 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 461 (24.68) | 18.7374 |
| 1990's | 334 (17.88) | 18.2507 |
| 2000's | 391 (20.93) | 29.6817 |
| 2010's | 536 (28.69) | 24.3611 |
| 2020's | 146 (7.82) | 2.80 |
| Authors | Studies |
|---|---|
| Davis, MC; Franzblau, SG; Martin, AR; Wächter, GA | 1 |
| Davis, MC; Franzblau, SG; Martin, AR | 1 |
| Bansal, NP; Dick, JD; Houston, TA; Jones, PB; Parrish, NM; Stapon, A; Townsend, CA | 1 |
| Franzblau, SG; Gezginci, MH; Martin, AR | 1 |
| Haritakul, R; Keller, PA; Morgan, J | 1 |
| Hashizume, H; Kawasaki, M; Komatsu, M; Matsumoto, M; Sasaki, H; Shimokawa, Y; Tomishige, T; Tsubouchi, H | 1 |
| Andries, K; Chauffour, A; Ibrahim, M; Jarlier, V; Lounis, N; Truffot-Pernot, C; Veziris, N | 1 |
| Cho, SH; Franzblau, SG; Hwang, CH; Pauli, GF; Wan, B; Warit, S | 1 |
| Imramovský, A; Jampílek, J; Kaustová, J; Kocevar, M; Polanc, S; Recková, Z; Vinsová, J | 1 |
| Chung, WJ; Jacobs, WR; Ngo, SC; Sayahi, H; Welch, JT; Zimhony, O | 1 |
| Byrne, ST; Chong, C; Denkin, SM; Gu, P; Liu, JO; Sullivan, D; Zhang, Y; Zhou, J | 1 |
| Basaraba, RJ; Brooks, EJ; Caraway, ML; Driver, ER; Hoff, DR; Lenaerts, AJ; Orme, IM; Peloquin, CA; Ryan, GJ | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Connell, TG; Curtis, N; Ritz, N; Robins-Browne, R; Sievers, A; Tebruegge, M | 1 |
| Karthikeyan, SV; Perumal, S; Shetty, KA; Sriram, D; Yogeeswari, P | 1 |
| Perumal, S; Ranjith Kumar, R; Senthilkumar, P; Sriram, D; Yogeeswari, P | 1 |
| Gaillard, JL; Jackson, M; McDonnell, G; Niederweis, M; Skovierová, H; Svetlíková, Z | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Rieder, RJ; Zavizion, B; Zhao, Z | 1 |
| Banerjee, D; Indumathi, S; Perumal, S; Sriram, D; Yogeeswari, P | 1 |
| Banerjee, D; Kumar, RS; Perumal, S; Rajesh, SM; Sriram, D; Yogeeswari, P | 1 |
| Bala, BD; Karthikeyan, SV; Perumal, S; Raja, VP; Sriram, D; Yogeeswari, P | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Franzblau, SG; He, R; Mao, J; Pak, D; Wan, B; Wang, Y; Yuan, H | 1 |
| Angulo-Barturen, I; Beltrán, M; Cáceres, N; Cardona, PJ; García, JI; García-Bustos, JF; Rullas, J | 1 |
| Fowler, JS; Hooker, JM; Liu, L; Shea, C; Tonge, PJ; Xu, Y | 1 |
| Manikannan, R; Muthusubramanian, S; Sriram, D; Yogeeswari, P | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Khanna, A; Pareek, PK; Raj, VS; Rattan, A; Saini, KS; Sharma, P; Singh, H; Sood, R; Tarai, B; Upadhyay, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Manikannan, R; Muthusubramanian, S; Sriram, D; Venkatesan, R; Yogeeswari, P | 1 |
| Kantevari, S; Patpi, SR; Sridhar, B; Sriram, D; Yogeeswari, P | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Perumal, S; Raja, VP; Sriram, D; Yogeeswari, P | 1 |
| Kantevari, S; Sridhar, B; Sriram, D; Yempala, T; Yogeeswari, P | 1 |
| Bosze, S; Horváti, K; Kočevar, M; Polanc, S; Stolaříková, J; Vavříková, E; Vávrová, K; Vinšová, J | 1 |
| Augustynowicz-Kopeć, E; Bojanowski, K; Foks, H; Gobis, K; Napiórkowska, A | 1 |
| Murugavel, M; Muthusubramanian, S; Paul, N; Sriram, D | 1 |
| Anjana Devi, T; Jain, N; Kalivendi, SV; Kantevari, S; Murthy, R; Patpi, SR; Pulipati, L; Sridhar, B; Sriram, D; Yogeeswari, P | 1 |
| Chikhalia, KH; Kumari, P; Patel, PK; Patel, RV; Rajani, DP | 1 |
| Chakrapani, H; Malwal, SR; Sriram, D; Yogeeswari, P | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Alexandrova, L; Andreevskaya, S; Chernousova, L; Chizhov, A; Karpenko, I; Khandazhinskaya, A; Kochetkov, S; Matyugina, E; Smirnova, T | 1 |
| Coffey, A; Csollei, J; Fajkusova, D; Guo, J; Jampilek, J; Keltosova, S; Kollar, P; Kralova, K; Oktabec, Z; Pesko, M; Vejsova, M | 1 |
| Kantevari, S; Sriram, D; Yempala, T; Yogeeswari, P | 1 |
| Doležal, M; Kubíček, V; Kuneš, J; Mandíková, J; Paterová, P; Trejtnar, F; Zitko, J | 1 |
| Doležal, M; Kubíček, V; Kuneš, J; Paterová, P; Servusová, B; Vobicková, J; Zitko, J | 1 |
| Alexandrova, LA; Andreevskaya, SN; Chernousova, LN; Chizhov, AO; Efremenkova, OV; Karpenko, IL; Kochetkov, SN; Shmalenyuk, ER; Smirnova, TG | 1 |
| Barry, CE; Dartois, V | 1 |
| Kantevari, S; Sridevi, JP; Sriram, D; Yempala, T; Yogeeswari, P | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Addla, D; Gurram, D; Jallapally, A; Kantevari, S; Sriram, D; Yogeeswari, P | 2 |
| Doležal, M; Kubíček, V; Kučera, R; Kuneš, J; Mandíková, J; Paterová, P; Servusová, B; Zitko, J | 1 |
| Chikhalia, KH; Kumari, P; Patel, AB | 1 |
| Charushin, VN; Kravchenko, MA; Medvinskiy, ID; Rusinov, GL; Verbitskiy, EV | 1 |
| Chaturvedi, V; Chauhan, K; Chauhan, PM; Sharma, M; Trivedi, P | 1 |
| Doležal, M; Garaj, V; Janoutová, A; Mandíková, J; Marek, J; Paterová, P; Servusová, B; Vejsová, M; Zitko, J | 1 |
| Augustynowicz-Kopeć, E; Foks, H; Gobis, K; Napiórkowska, A; Serocki, M | 1 |
| Gowri Chandra Sekhar, KV; Nagesh, HN; Naidu, KM; Singh, M; Sriram, D; Yogeeswari, P | 1 |
| Bharate, SS; Vishwakarma, RA | 1 |
| Achur, R; Dalimba, U; Kumar, HS; Nayak, N; Peethambar, SK; Ramprasad, J; Sriram, D; Yogeeswari, P | 1 |
| Augustynowicz-Kopeć, E; Bojanowski, K; Foks, H; Gobis, K; Napiórkowska, A; Suchan, K | 1 |
| Bera, S; Chaturvedi, V; Jana, AK; Kumar M, SL; Manna, SK; Mishra, P; Mondal, S; Panda, G; Parai, MK; Saha, T; Singh, P; Singh, S; Sinha, S; Trivedi, P | 1 |
| Charushin, VN; Cheprakova, EM; Chupakhin, ON; Kravchenko, MA; Rusinov, GL; Skornyakov, SN; Slepukhin, PA; Verbitskiy, EV | 1 |
| Askri, M; Boudriga, S; Golz, C; Knorr, M; Mhiri, C; Nana, F; Sriram, D; Strohmann, C; Yogeeswari, P | 1 |
| Dalimba, U; Nayak, N; Ramprasad, J; Sriram, D; Yogeeswari, P | 1 |
| Dalimba, U; Nayak, N; Ramprasad, J | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Arkile, MA; Asgaonkar, KD; Chitre, TS; Dharme, AB; Jha, PC; Khedkar, VM; Miniyar, PB; Sarkar, D; Yeware, A | 1 |
| Chakraborti, AK; Dhameliya, TM; Jadhavar, PS; Pancholia, S; Shah, P; Sridevi, JP; Sriram, D; Yogeshwari, P | 1 |
| Chakraborti, AK; Dhameliya, TM; Jadhavar, PS; Kumar, D; Sridevi, JP; Sriram, D; Vaja, MD; Yogeeswari, P | 1 |
| Kantevari, S; Pulipati, L; Sriram, D; Yogeeswari, P | 1 |
| Kantevari, S; Pulipati, L; Sridevi, JP; Sriram, D; Yogeeswari, P | 1 |
| Kantevari, S; Sriram, D; Surineni, G; Yogeeswari, P | 1 |
| Baskakova, SA; Charushin, VN; Chupakhin, ON; Kravchenko, MA; Rusinov, GL; Skornyakov, SN; Verbitskiy, EV | 1 |
| Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
| Chegaev, K; Chung, MC; de Souza, PC; Dos Santos, JL; Fernandes, GFDS; Fruttero, R; Guglielmo, S; Lazzarato, L; Marino, LB; Pavan, FR | 1 |
| Beuerman, RW; Cao, D; Corkran, HM; Dick, T; Koh, JJ; Lakshminarayanan, R; Lim, F; Lin, S; Liu, S; Mukherjee, D; Stocker, BL; Tan, DTH; Tan, DZ; Tan, JK; Timmer, MSM; Zou, H | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Chakraborti, AK; Kumar, A; Sriram, D; Tanwar, B; Yogeeswari, P | 1 |
| Balaji, NV; Hari Babu, B; Murali Krishna Kumar, M; Purna Nagasree, K; Subbaraju, GV | 1 |
| Feng, LS; Gao, C; Hu, YQ; Lv, ZS; Wu, X; Xu, Z; Zhang, S; Zhao, F | 1 |
| Baskakova, SA; Charushin, VN; Chupakhin, ON; Evstigneeva, NP; Gerasimova, NA; Kravchenko, MA; Kungurov, NV; Pervova, MG; Rusinov, GL; Skornyakov, SN; Verbitskiy, EV; Zil'berberg, NV | 1 |
| Chang, L; Feng, LS; Gao, C; Lv, ZS; Ren, QC; Xu, Z; Zhang, S | 1 |
| Feng, LS; Gao, C; Lv, ZS; Ren, QC; Song, XF; Xu, Z | 1 |
| Aiub, CAF; Araujo-Lima, CF; Boechat, N; Castelo-Branco, FS; Costa, TEMM; Costa-Lima, MM; de Lima, EC; Domingos, JLO; Felzenszwalb, I; Gomes, KM; Henriques, MG; Lourenço, MCS; Penido, C; Pinto, AC | 1 |
| Fan, YL; Feng, LS; Gao, T; Huang, ZP; Jin, XH; Yu, HF; Zeng, ZG | 1 |
| Kantevari, S; Marvadi, SK; Sriram, D; Surineni, G; Yogeeswari, P | 1 |
| Banerjee, A; Chakraborti, AK; Dhameliya, TM; Pancholia, S; Panda, D; Sriram, D; Tiwari, R | 1 |
| Ashok, D; Goud, GL; Manga, V; Ramesh, S; Reddy, VP; Saikrishna, B; Sriram, D; Yogeeswari, P | 1 |
| Bai, L; Deng, J; Feng, L; Lv, Z; Wang, Y; Xu, Z; Zhang, F; Zhao, S | 1 |
| Dalimba, U; Madan Kumar, S; Reddyrajula, R | 1 |
| Bera, S; Mondal, D | 1 |
| Mabhula, A; Singh, V | 1 |
| Augustynowicz-Kopeć, E; Bojanowski, K; Foks, H; Gobis, K; Głogowska, A; Korona-Głowniak, I; Krause, M; Siluk, D; Ziembicka, D | 1 |
| Jayathirtha Rao, V; Kishore, G; Kumar, SB; Ravinder, M; Sriram, D; Yogeeswari, P | 1 |
| Agafonova, NA; Borisevich, SS; Burgart, YV; Chupakhin, ON; Evstigneeva, NP; Gerasimova, NA; Krasnykh, OP; Kungurov, NV; Kushch, SO; Makhaeva, GF; Maslova, VV; Rudakova, EV; Saloutin, VI; Shchegolkov, EV; Solodnikov, SY; Triandafilova, GA; Ulitko, MV; Zilberberg, NV | 1 |
| Rakesh, KP; Tiwari, SP; Vaishnav, Y; Verma, R; Verma, S; Verma, SK | 1 |
| Cordeiro, R; Kachroo, M | 1 |
| Dhawan, S; Girase, PS; Karpoormath, R; Kumar, V; Palkar, MB; Shinde, SR | 1 |
| Trotsko, N | 1 |
| Bayannavar, PK; Hoolageri, SR; Joshi, SD; Kamble, RR; Kodasi, B; Kumbar, VM; Nesaragi, AR; Shaikh, SKJ | 1 |
| Ahmad, I; Alshahrani, MY; Jain, R; Pradeep Kumar, CB; Prashanth, MK; Raghu, MS; Yogesh Kumar, K | 1 |
| Agrahari, AK; Rajkhowa, S; Sharma, A; Tiwari, VK | 1 |
| Martin, PD | 1 |
| Bates, JH | 1 |
| Fox, W; Mitchison, DA | 2 |
| Newton, RW | 1 |
| Rossouw, JE; Saunders, SJ | 1 |
| Jindani, A | 2 |
| Springett, VH | 1 |
| Clarke, PD | 1 |
| Angel, JH | 2 |
| Pearson, JO | 2 |
| Mitchison, DA | 6 |
| Fox, W; Nunn, AJ | 1 |
| Gow, JG | 4 |
| Chan, SL | 1 |
| Girling, DJ | 2 |
| Aquinas, M | 1 |
| Grosset, J; Perdrizet, S; Pretet, S | 1 |
| Aber, VR; Dickinson, JM; Mitchison, DA | 1 |
| Morgan, EJ | 1 |
| Eule, H | 1 |
| Johnston, RF; Promisloff, RA | 1 |
| Balogh, F; Borthwick, WM; Mallo, N; Mazurek, L; Trnka, L; Victorov, J | 1 |
| Fallon, RJ | 1 |
| Utkin, VV | 1 |
| Ait Khaled, N; Benachenhou, A; Chaulet, P; Fekar, A; Virot, JP | 1 |
| Parthasarathy, R; Ramakrishnan, CV; Sambamoorthy, S; Somasundaram, PR; Subbammal, S | 1 |
| Hinshaw, HC | 1 |
| Iatsozhinskiĭ, IuD; Kulik, NM; Molotkov, VN | 1 |
| Allan, WG | 2 |
| Heffernan, JF | 1 |
| Allen, BW; Ellard, GA; Gammon, PT; King, RC; McDougall, AC; Rees, RJ; Weddell, AG | 1 |
| Sifontes, JE | 1 |
| Kumar, L | 1 |
| Kwan, SY; Lee, J; Wong, PC; Yew, WW | 1 |
| Abdi, A; Lema, E; Roscigno, G; Wolde, K | 1 |
| Arora, R; Arora, VK; Oumachigui, A; Rajaram, P | 1 |
| Kumaresan, JA; Maganu, ET | 1 |
| Yu, BZ | 1 |
| Schmidt, M | 1 |
| Hitoglou-Makedou, A; Pratsidou, P; Sofroniadis, I; Tsakalidis, D; Tzouvelekis, G | 1 |
| Nolan, CM | 1 |
| Chotpitayasunonah, T; Jacobs, RF; Kelleher, K; Pope, S; Sunakorn, P | 1 |
| Khoo, SH; Warner, TT; Wilkins, EG | 1 |
| Kovaleva, SI | 1 |
| Pust, RE | 1 |
| Grosset, J; Ji, B; Lacroix, C; Truffot-Pernot, C | 1 |
| Misra, RS; Mukherjee, A; Ramesh, V; Saxena, U | 1 |
| Lalwani, AK; Lee, KC; Schecter, G; Tami, TA | 1 |
| Singhal, KC; Varshney, MK | 1 |
| Donald, PR; Parkin, DP; Seifart, HI | 1 |
| Adrados, M; Díaz, F; García Aguado, C; González Lahoz, JM; Laguna, F; Martínez, R; Puente, S | 1 |
| Cramer, G; Hamel, U; Roth, G; Wiesner, B | 1 |
| Alexander, M; Held, T; Mielke, M; Reichelt, A; Rössler, W | 1 |
| Skakun, NP; Slivka, IuI | 1 |
| Lode, H; Schaberg, T | 2 |
| Chaisson, RE; Goodman, PC; Hopewell, PC; Sande, MA; Schecter, GF; Small, PM | 1 |
| Crowle, AJ; Dahl, R; May, MH; Ross, E | 1 |
| Horsfield, N; McCarthy, OR; Ormerod, LP; Rudd, RM | 2 |
| Dickinson, JM; Mitchison, DA | 2 |
| Chan, HS; Chan, K; Walubo, A; Wong, CL; Woo, J | 2 |
| Kaojarern, S; Krittiyanunt, S; Mokkhavesa, C; Phuapradit, P; Supmonchai, K | 1 |
| Gupta, EV; Rac, VV; Thomas, IM | 1 |
| Curtis, G; Fleenor, ME; Harden, JW | 1 |
| O'Brien, RJ | 1 |
| Gaitonde, CD; Pathak, PV | 1 |
| Catlin, BJ; Cohn, DL; Judson, FN; Peterson, KL; Sbarbaro, JA | 1 |
| Agounitestane, D; Ait Khaled, N; Boulahbal, F; Chaulet, P; Chiheb, M; Khaled, S | 1 |
| Magnussen, H; Nowak, D; Radenbach, D | 2 |
| Croughan, M; Harris, G; Rayner, A; Watt, B | 1 |
| Balasubramanian, R; Jawahar, MS; Paramasivan, CN; Ramachandran, R; Selvakumar, N; Sivasubramanian, S; Somasundaram, PR; Vijayan, VK | 1 |
| Crowle, AJ; May, MH | 1 |
| Combs, DL; Geiter, LJ; O'Brien, RJ | 1 |
| Brink, BA; Cowie, RL | 1 |
| Campbell, IA | 1 |
| Kusema, T; Mhonda, M; Neill, P; Nhachi, CF; Pringle, D | 1 |
| Iurchenko, LN; Koriakin, VA; Onishchenko, VV; Shapatava, MN; Sokolova, GB | 1 |
| Farrell, VJ | 1 |
| Alarcón, F; Banda, H; Chacón, G; Dueñas, G; Escalante, L; Pérez, Y | 1 |
| Morland, L | 1 |
| Blumberg, EA; Gil, RA | 1 |
| Dhand, R; Katariya, S; Kumar, L; Rao, KL; Singhi, PD | 1 |
| Fox, W | 5 |
| Cheung, WL; Ng, A; Siu, KF | 1 |
| Pitchenik, AE | 1 |
| Loos, U; Musch, E; Schwabe, HK | 1 |
| Benatar, SR; Maartens, G; Willcox, PA | 1 |
| Holdiness, MR | 2 |
| Mitchison, DA; Nunn, AJ | 1 |
| Katoch, K; Ramanathan, U; Ramu, G | 1 |
| Daramas, M; Jittinandana, A; Kecharanandana, P; Payanandana, W | 1 |
| Aziz, A; Aziz, K; Ishaq, M; Siddiqi, SH | 1 |
| Jittinandana, A | 1 |
| Domingo, Z; Peter, JC | 1 |
| McCarthy, OR; Rudd, RM | 1 |
| Heap, BJ | 1 |
| Tournier, G | 1 |
| Ladron de Guevara, R | 1 |
| Abtroun, N; Amrane, R; Boulahbal, F; Mazouni, L; Zidane, C | 1 |
| Bellabas, M; Boulahbal, F; Chaulet, P; Khaled, NA; Khaled, S | 1 |
| Baumann, HR; Bohn, W; Brändli, O; Haegi, V; Villiger, B; Zäch, R | 1 |
| Bellon, G; Gallet, S | 1 |
| Iusukhno, EE; Khomenko, VV; Petrovich, DI; Porokhnia, VV; Skvira, VP | 1 |
| Felten, MK | 1 |
| Klimniuk, EV; Slivka, IuI; Tabachuk, OE | 1 |
| Acocella, G | 2 |
| Chan, JC; Humphries, MJ; Ng, HK; O'Mahony, G; Teoh, R | 1 |
| Fischer, P; Merkel, S; Weinecke, W | 1 |
| Dhillon, J; Mitchison, DA | 1 |
| Grosset, JH; Lecoeur, HF; Truffot-Pernot, C | 1 |
| Zeis, BM | 1 |
| Donald, PR; O'Kennedy, A; Schoeman, JF | 1 |
| Aeberhardt, G; Bernheim, J; Dautzenberg, B; Gallinari, C; Grosset, J; Lévy, A; Sors, C | 1 |
| Beurey, J; Cuny, JF; Schmutz, JL; Trechot, P; Weber, M | 1 |
| Ellis, ME; Tayoub, F | 1 |
| Aluoch, JA; Babu Swai, O; Darbyshire, JH; Edwards, EA; Githui, WA; Nunn, AJ; Thiong'o, R | 1 |
| Nariman, S | 1 |
| Ashtekar, DR; Fernandes, F; Khadse, BG; Shirodkar, MV | 1 |
| Xu, RX | 1 |
| Azuma, Y; Baba, H; Izuchi, R; Shinkai, A | 1 |
| Desai, SG; Trivedi, SS | 1 |
| Hawkins, DB; Kahlstrom, EJ; Schwartz, MS | 1 |
| Collins, CH; Uttley, AH | 1 |
| Grosset, JH; Lecoeur, H; Truffot-Pernot, C | 1 |
| Acocella, G; Gialdroni-Grassi, G; Grassi, C; Nonis, A | 1 |
| Acocella, G; Gialdroni-Grassi, G; Grassi, C; Nonis, A; Patane, E; Perna, G | 1 |
| Ormerod, LP | 1 |
| Boulahbal, F; Chaulet, P; Hamadi, A; Khaled, S | 1 |
| Goldberger, MJ | 1 |
| Kleeberg, HH | 1 |
| Lee, CN; Lee, JJ; Lin, TP; Suo, J; Yang, SP | 1 |
| Czaplińska-Jóźwiak, E; Szymański, A | 1 |
| Combs, DL; Geiter, LJ; O'Brien, RJ; Snider, DE | 1 |
| Blanco Palenciano, J; Blanco Roca, MT; González Roiz, C; Martínez Oliva, C; Muñoz Sanz, A; Prieto Prieto, J; Puente Ranz, LF | 1 |
| Elias-Jones, AC; Heard, SR; Leitch, RN; Sequeira, J | 1 |
| Rieder, HL | 2 |
| Bek, E; Farer, LS; Graczyk, J; Snider, DE; Zierski, M | 1 |
| Des Prez, RM; Sheller, JR | 1 |
| Ramírez, O; Ramírez, R | 1 |
| Beck, H; Eule, H; Evers, H; Fischer, P; Kwiatkowski, H; Merkel, S; Reech, R; Sieler, R; Thomas, E; Weinecke, W | 1 |
| Davidson, PT; Hanh, LQ | 1 |
| Aderinto, EB; Awotedu, AA; Ogunbanjo, BO; Onadeko, BO | 1 |
| Adendorff, JJ; Boeke, EJ; Lazarus, C | 1 |
| Corsello, BF | 1 |
| Geiter, LJ; O'Brien, RJ | 1 |
| Phuapradit, P; Vejjajiva, A | 1 |
| Horsfield, N; Ormerod, LP | 1 |
| Van Scoy, RE; Wilkowske, CJ | 2 |
| Kamińska, M; Kopeć, H; Maternowska, W; Nikodemowicz, E; Prus, F; Sembratowicz, L | 1 |
| Duraipandian, M; Nagarajan, M; Prabhakar, R; Ramachandran, P; Ramakrishnan, CV; Tripathy, SP | 1 |
| Allen, BW; Chan, SL; Ellard, DR; Ellard, GA; Girling, DJ; Ng, HK; Nunn, AJ; Tan, TH; Teo, SK | 1 |
| Berkani, M; Chaulet, P; Darbyshire, JH; Fox, W; Nunn, A | 1 |
| Crewe-Brown, HH; Glatthaar, E; McCutcheon, JP; Summers, RS | 1 |
| Behari, M; Maheshwari, MC; Pauranik, A | 1 |
| Engelhard, M; Layer, P | 1 |
| Janardhanam, B; Parthasarathy, R; Ramachandran, P; Santha, T; Sarma, GR; Sivasubramanian, S; Somasundaram, PR; Tripathy, SP | 1 |
| Acocella, G; Angel, JH | 1 |
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| Mistry, N; Oswal, V; Rao, S; Shaikh, A; Sriraman, K; Vaswani, S | 1 |
| Karthikeyan, K; Premjith, R; Vijayasankar, P | 1 |
| Almond, L; Berg, A; Gardner, I; Hatley, O; Humphries, H; Jamei, M; Pan, X; Romero, K; Small, B; Zhang, M | 1 |
| Bekker, A; Davies, G; Denti, P; Gonzalez-Martinez, C; Hesseling, AC; McIlleron, HM; Rabie, H; Svensson, EM; van der Laan, LE; van Rie, A; Wasmann, RE; Wiesner, L; Winckler, J; Zar, HJ | 1 |
| Bollela, VR; Della Pasqua, O; Lanchote, VL; Nardotto, GHB; Rocha, A | 1 |
| Bandere, D; Cirule, A; Grinberga, S; Igumnova, V; Kivrane, A; Krams, A; Pole, I; Pugovics, O; Ranka, R; Sevostjanovs, E; Viksna, A | 1 |
| Chen, H; Chen, N; Huang, C; Li, Y; Nie, Q; Tang, Q; Tao, L; Wang, X; Wang, Y; Yang, C; Zhou, Y | 1 |
| Alsultan, A; Byun, MK; Cho, I; Choi, H; Geiter, L; Joh, JS; Kang, JY; Kang, YS; Kim, H; Kim, JS; Kim, JW; Kim, SJ; Kim, SK; Kim, TH; Kim, YH; Lee, SH; Lim, HS; Mok, J; Park, HJ; Park, YB; Shen, X; Shim, TS; Yang, J | 1 |
| Kumari, D; Perveen, S; Sharma, R; Singh, K | 1 |
| Chen, G; Liu, K; Liu, L; Wang, X; Wu, F; Yang, Y; Zhang, Y; Zou, H | 1 |
| Allen, L; Carr, W; Goswami, N; Kurbatova, E; Starks, A; Winston, C | 1 |
| Álvarez Álvarez, B; Calpena Martínez, S; Carrillo Acosta, I; Górgolas Hernández-Mora, M | 1 |
| Della Pasqua, O; Ferrer, S; Muliaditan, M; Ortega-Muro, F; Teutonico, D | 1 |
| Aarnoutse, R; Bhavani, PK; Chabala, C; Choo, L; Crook, AM; Demers, AM; Gibb, DM; Graham, SM; Hesseling, AC; Hissar, S; Joseph, B; Kapasa, M; Kinikar, A; LeBeau, K; Love-Koh, J; Mave, V; Mboizi, RB; McIlleron, H; Mulenga, V; Musoke, P; Palmer, M; Raichur, P; Seddon, JA; Thomason, MJ; Turkova, A; van der Zalm, MM; Welch, SB; Wills, GH; Wobudeya, E | 1 |
| Alffenaar, JC; Augustinsson, D; Bornefall, A; Carlsson, B; Ekqvist, D; Fredrikson, M; Niward, K; Nordvall, MJ; Paues, J; Sandstedt, M; Simonsson, USH; Sönnerbrandt, M | 1 |
| Carr, W; Converse, PJ; Dartois, V; Dooley, KE; Garcia, A; Kurbatova, E; Nuermberger, EL; Stout, JE; Tasneen, R; Vernon, AA; Zimmerman, MD | 1 |
| Chasweka, M; Chirambo, AP; Chitani, A; Corbett, EL; Davies, GR; Ghany, JF; Gordon, SB; Khoo, SH; Malamba, R; Mallewa, JE; McCallum, AD; Meghji, JZ; Mwandumba, HC; Pertinez, HE; Shani, D; Sheha, I; Sloan, DJ | 1 |
| Anderson, R; Cholo, MC; Mashele, SA; Matjokotja, MT; Rasehlo, SSM; Steel, HC | 1 |
| Abulfathi, AA; Carter, CL; Dartois, V; Decloedt, EH; Demers, AM; Deventer, AV; Garcia-Prats, AJ; Goussard, P; Hesseling, AC; Janson, J; Lopez-Varela, E; Morrison, J; Reuter, H; Savic, RM; Seddon, JA; Strydom, N; Svensson, EM; van der Merwe, J; van Wyk, AC; Warren, R; Zimmerman, M | 1 |
| Byeon, SJ; Choi, JH; Chung, SJ | 1 |
| Abouhareb, R; Alasadi, L; Alrstom, A; Alsuliman, T; Daher, N; Karam, B; Mohandes, AF; Rajab Bek, MW | 1 |
| Anderson, G; Vinnard, C | 1 |
| Alshaer, MH; Gratz, J; Heysell, SK; Houpt, ER; Justine, M; Kosek, M; Liu, J; Maro, A; Mduma, E; Mpagama, SG; Mujaga, B; Peloquin, CA; Rogawski McQuade, ET; Thomas, TA; Van Aartsen, D | 1 |
| Chimbetete, T; Choshi, P; Lehloenya, R; Meintjes, G; Pedretti, S; Peter, J; Phillips, E; Porter, M; Smith, R | 1 |
| Wen, Y; Wu, X; Zhang, G | 1 |
| Arodola-Oladoyinbo, O; Chirehwa, M; Denti, P; Gengiah, TN; Kawuma, AN; Naidoo, A; Naidoo, K; Padayatchi, N; Perumal, R | 1 |
| Chen, X; Ding, Y; Fu, L; Guo, S; Liu, H; Lu, Y; Wang, B; Wang, N; Zhang, W; Zhu, H | 1 |
| Addise, D; Beyene, D; Merker, M; Mesfin, EA; Niemann, S; Shuaib, YA; Tesfaye, A; Tessema, B | 1 |
| Cheon, M; Hahn, S; Jeon, D; Kang, YA; Kim, HJ; Kim, KJ; Kim, YR; Kwak, N; Kwon, BS; Kwon, YS; Lee, JH; Lee, JK; Lee, JY; Mok, J; Park, J; Park, Y; Yim, JJ | 1 |
| Bennie, M; Godman, B; Kruger, D; Kurdi, A; Meyer, JC; Schellack, N; Skosana, PP | 1 |
| Kang, JY; Kim, HW; Kim, JS; Kim, JW; Kim, SK; Kim, YH; Lee, SH; Min, J; Yoon, HK | 1 |
| Glenn, SM; Kell, DB; Makarov, V; Mukamolova, GV; Turapov, O | 1 |
| George, S; Gerbo, RM; Hartman-Adams, H | 1 |
| Mlisana, KP; Mvelase, NR; Singh, R; Swe Swe-Han, K | 1 |
| Kilonzo, K; Lyamuya, F; Mremi, A; Sadiq, A; Temba, B; Urassa, D; Vara, P | 1 |
| Alfarisi, O; Barthwal, M; Deshmukh, S; Dharmshale, S; Dooley, KE; Gaikwad, S; Golub, JE; Gupta, A; Gupte, A; Gupte, N; Kagal, A; Lokhande, R; Mave, V; Pradhan, N; Raskar, S; Sahasrabudhe, T; Sane, M | 1 |
| Kamoshita, F; Karaushi, H; Mitsutake, K; Miyawaki, Y; Seki, M; Watanabe, N | 1 |
| Castel, S; Court, R; Joubert, A; Loveday, M; Norman, J; van der Merwe, M; Waitt, C; Wiesner, L; Zuma, P | 1 |
| Amengor, CDK; Ben, IO; Biniyam, PD; Danquah, CA; Harley, BK; Orman, E | 1 |
| Brankin, A; Colman, RE; Georghiou, SB; Seifert, M; Suresh, A; Uplekar, S; Walker, TM | 1 |
| Di Palma, M; Francis, JR; Globan, M; Hall, C; Hersch, N; Horan, K; Lopes, C; Meumann, EM; Pereira, HM; Ralph, AP; Sarmento, N | 1 |
| Cáceres-Pérez, AR; Fariña, JB; Oliva, A; Santoveña-Estévez, A; Suárez-González, J | 1 |
| Aarnoutse, RE; Agarwal, D; Alffenaar, JC; Antwi, S; Bang, ND; Bekker, A; Bell, DJ; Chabala, C; Choo, L; Davies, GR; Day, JN; Dayal, R; Denti, P; Donald, PR; Engidawork, E; Gafar, F; Garcia-Prats, AJ; Gibb, D; Graham, SM; Hesseling, AC; Heysell, SK; Idris, MI; Kabra, SK; Kinikar, A; Kumar, AKH; Kwara, A; Lodha, R; Magis-Escurra, C; Marais, BJ; Martinez, N; Mathew, BS; Mave, V; McIlleron, HM; Mduma, E; Mlotha-Mitole, R; Mpagama, SG; Mukherjee, A; Nataprawira, HM; Peloquin, CA; Pouplin, T; Ramachandran, G; Ranjalkar, J; Roy, V; Ruslami, R; Schaaf, HS; Shah, I; Singh, Y; Stevens, J; Sturkenboom, MGG; Svensson, EM; Swaminathan, S; Taxis, K; Thatte, U; Thee, S; Thomas, TA; Tikiso, T; Touw, DJ; Turkova, A; Velpandian, T; Verhagen, LM; Wasmann, RE; Winckler, JL; Yang, H; Yunivita, V | 1 |
| Kertys, M; Mokrý, J; Porvazník, I; Pršo, K; Solovič, I; Žideková, N | 1 |
| Bhadauria, M; Nirala, SK; Rakshit, S; Sahu, N | 1 |
| Barnes, G; Dawson, R; Dooley, KE; Dorman, SE; Friedman, A; Gupte, N; Hendricks, B; Ignatius, EH; Narunsky, K; Smit, T; Whitelaw, C | 1 |
| Béranger, A; Gegia, M; Linh, NN; Mirzayev, F; Mohamed, A; Nahid, P; Radtke, K; Savic, RM; Schumacher, SG; Solans, BP | 1 |
| Bharathiraja, T; Hemanth Kumar, AK; Kannan, T; Lavanya, J; Mary Rebecca, Y; Sudha, V | 1 |
| Avihingsanon, A; Balanag, VM; Burhan, E; Chew, KL; Cousins, C; Crook, AM; Dalay, VB; Djaharuddin, I; Kusmiati, T; Lee, SL; Lu, Q; Nunn, AJ; Papineni, P; Paton, NI; Pokharkar, Y; Ruslami, R; Sarin, R; Sekaggya-Wiltshire, C; Sugiri, JJR; Suresh, C; Veto, RS | 1 |
| Chen, L; Clemens, DL; Ding, X; Gu, J; Gui, X; Hao, X; He, Y; Ho, CM; Horwitz, MA; Lee, BY; Liu, Y; Lou, H; Ma, J; Sha, W; Sun, Q; Yang, H; Yao, L; Ying, R; Zheng, X | 1 |
| Naidoo, A; Naidoo, K; Padayatchi, N; Perumal, R | 1 |
| Dartois, V; Mittereder, LR; Namasivayam, S; Oland, S; Sher, A; Wang, H; Zimmerman, M | 1 |
| Bao, Z; Cao, H; Davies Forsman, L; Hoffner, S; Hu, Y; Li, X; Liu, J; Ning, Z; Wang, S; Zhu, J | 1 |
| Balijepalli, MK; Butti, L; Kandra, N; Masapogu, S; Somarouthu, VS; Uppala, PK; Uttaravalli, U; Vangoori, Y; Varghese, AM | 1 |
| Chen, X; Feng, Z; Ge, S; Li, R; Li, Y; Miao, Y; Peng, Y; Song, L; Sun, F; Wang, X; Zhang, W; Zhang, Y | 1 |
| Ezhilarasan, D | 1 |
| Bakshi, S; Kaur, M; Sharma, S; Verma, A | 1 |
| Brehm, TT; Friesen, I; Heyckendorf, J; Kalsdorf, B; Kandulla, J; Köhler, N; Kuhns, M; Lange, C; Martensen, J; Schmiedel, S; Terhalle, E | 1 |
| Gadgil, CJ; Ramachandran, A | 1 |
| Chen, S; Fu, S; Hou, P; Li, H; Li, Q; Li, S; Liu, X; Liu, Y; Ma, Y; Zhang, H | 1 |
| Aalhoul, F; Cotton, F; Fage, D | 1 |
| Adeel, A; Ahmad, A; Ahmad, I; Aslam, H; Mushtaq, F; Raza, SM; Saleem, S | 1 |
| Aarnoutse, R; Chabala, C; Cotton, MF; Denti, P; Galileya, LT; Gibb, D; Hesseling, A; Lee, J; McIlleron, H; Njahira Mukui, I; Rabie, H; Turkova, A; Wasmann, RE; Zar, H | 1 |
| Alshaer, MH; Amissah, AK; Antwi, S; Appiah, AF; Bosomtwe, D; Dompreh, A; Dong, SK; Enimil, A; Kusi-Amponsah, I; Kwara, A; Maranchick, N; Martyn-Dickens, C; Morgan, R; Ojewale, O; Opoku, T; Osei Kuffour, B; Peloquin, CA; Sarfo, AD; Sly-Moore, E; Yang, H | 1 |
| Choudhary, S; Joshi, D; Sahni, M; Srivastava, A | 1 |
136 review(s) available for pyrazinamide and isoniazid
| Article | Year |
|---|---|
A medicinal chemists' guide to the unique difficulties of lead optimization for tuberculosis.
Topics: Animals; Antitubercular Agents; Drug Discovery; Humans; Lung; Mycobacterium tuberculosis; Tuberculosis | 2013 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Isoniazid derivatives and their anti-tubercular activity.
Topics: Animals; Antitubercular Agents; Drug Discovery; Humans; Isoniazid; Mycobacterium tuberculosis; Tuberculosis; Tuberculosis, Multidrug-Resistant | 2017 |
Triazole derivatives and their anti-tubercular activity.
Topics: Antitubercular Agents; Dose-Response Relationship, Drug; Humans; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship; Triazoles; Tuberculosis | 2017 |
Recent advances of pyrazole-containing derivatives as anti-tubercular agents.
Topics: Antitubercular Agents; Dose-Response Relationship, Drug; Humans; Molecular Structure; Mycobacterium tuberculosis; Pyrazoles; Structure-Activity Relationship; Tuberculosis | 2017 |
Recent advances of imidazole-containing derivatives as anti-tubercular agents.
Topics: Animals; Antitubercular Agents; Dose-Response Relationship, Drug; Humans; Imidazoles; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship; Tuberculosis | 2018 |
Benzofuran derivatives and their anti-tubercular, anti-bacterial activities.
Topics: Anti-Bacterial Agents; Antitubercular Agents; Benzofurans; Humans; Structure-Activity Relationship | 2019 |
Insights of synthetic analogues of anti-leprosy agents.
Topics: Humans; Leprostatic Agents; Leprosy; Structure-Activity Relationship | 2019 |
Drug-resistance in
Topics: | 2019 |
Anti-tuberculosis activity and its structure-activity relationship (SAR) studies of oxadiazole derivatives: A key review.
Topics: Animals; Antitubercular Agents; Drug Discovery; Humans; Models, Molecular; Mycobacterium tuberculosis; Oxadiazoles; Structure-Activity Relationship; Tuberculosis | 2021 |
An appraisal of anti-mycobacterial activity with structure-activity relationship of piperazine and its analogues: A review.
Topics: Animals; Antitubercular Agents; Drug Design; Drug Discovery; Humans; Mycobacterium tuberculosis; Piperazine; Structure-Activity Relationship; Tuberculosis | 2021 |
Antitubercular properties of thiazolidin-4-ones - A review.
Topics: Animals; Antitubercular Agents; Chlorocebus aethiops; Humans; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium; Structure-Activity Relationship; Thiazolidines; THP-1 Cells; Vero Cells | 2021 |
Emerging impact of triazoles as anti-tubercular agent.
Topics: Antitubercular Agents; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Structure-Activity Relationship; Triazoles; Tuberculosis | 2022 |
Treatment of tuberculosis.
Topics: Adult; Aminosalicylic Acids; Capreomycin; Child; Cycloserine; Drug Resistance, Microbial; Drug Therapy, Combination; Ethambutol; Ethionamide; Humans; Isoniazid; Kanamycin; Middle Aged; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Streptomycin; Time Factors; Tuberculosis; Viomycin | 1975 |
Advances in the treatment of tuberculosis.
Topics: Aminosalicylic Acids; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Pyrazinamide; Rifampin; Streptomycin; Thioacetazone; Tuberculosis; Tuberculosis, Lymph Node; Tuberculosis, Meningeal; Tuberculosis, Miliary; Tuberculosis, Osteoarticular; Tuberculosis, Pulmonary; Tuberculosis, Urogenital | 1976 |
The hepatic toxicity of antituberculosis regimens containing isoniazid, rifampicin and pyrazinamide.
Topics: Acetylation; Adolescent; Adult; Aged; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Liver Function Tests; Middle Aged; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 1978 |
Failure of therapy for tuberculosis in human immunodeficiency virus infection.
Topics: Adolescent; Adult; AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; Drug Therapy, Combination; Ethambutol; Female; HIV Seropositivity; Humans; Isoniazid; Male; Mycobacterium tuberculosis; Pyrazinamide; Pyridoxine; Rifampin; Tuberculosis | 1992 |
[Chemoprophylaxis of tuberculosis (lecture)].
Topics: Adolescent; Adult; Age Factors; Antitubercular Agents; BCG Vaccine; Child; Ethambutol; Humans; Infant, Newborn; Isoniazid; Pyrazinamide; Rifampin; Time Factors; Tuberculosis | 1992 |
[Pharmacokinetic aspects of tuberculosis therapy with a fixed combination of rifampicin, isoniazide and pyrazinamide].
Topics: Biological Availability; Drug Therapy, Combination; Humans; Isoniazid; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 1991 |
[Therapy of tuberculosis].
Topics: Antitubercular Agents; Contraindications; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Prothionamide; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis | 1990 |
Adverse cutaneous reactions to antituberculosis drugs.
Topics: Acne Vulgaris; Adult; Amikacin; Antitubercular Agents; Drug Hypersensitivity; Ethambutol; Ethionamide; Female; Humans; Isoniazid; Male; Middle Aged; Pellagra; Pigmentation Disorders; Prothionamide; Pyrazinamide; Rifampin; Skin Diseases; Streptomycin; Thioacetazone | 1985 |
Chromatographic analysis of antituberculosis drugs in biological samples.
Topics: Aminosalicylic Acids; Antitubercular Agents; Capreomycin; Chromatography; Cycloserine; Ethambutol; Ethionamide; Humans; Isoniazid; Kanamycin; Kinetics; Monitoring, Physiologic; Pyrazinamide; Rifampin; Streptomycin; Thioacetazone; Viomycin | 1985 |
[Which treatment for primary tuberculosis?].
Topics: Acquired Immunodeficiency Syndrome; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis | 1989 |
Adverse reactions to drugs used in the treatment of tuberculosis.
Topics: Antitubercular Agents; Drug Hypersensitivity; Humans; Isoniazid; Pyrazinamide; Rifampin; Streptomycin | 1988 |
Antituberculosis agents.
Topics: Antitubercular Agents; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 1988 |
CNS tuberculosis.
Topics: Biopsy; Cerebral Ventricles; Cerebrospinal Fluid; Ethambutol; Humans; Hyaluronoglucosaminidase; Isoniazid; Nervous System Diseases; Prognosis; Pyrazinamide; Rifampin; Streptomycin; Tomography, X-Ray Computed; Tuberculoma; Tuberculosis, Meningeal | 1986 |
Respiratory pharmacology. Antituberculosis drugs.
Topics: Aminosalicylic Acids; Antitubercular Agents; Cyclosporins; Ethambutol; Humans; Isoniazid; Pyrazinamide; Rifampin; Tuberculosis | 1986 |
[Treatment of pleuropulmonary tuberculosis in 1985].
Topics: Aminoglycosides; Antitubercular Agents; Ethambutol; Humans; Isoniazid; Pyrazinamide; Rifampin; Thioamides; Tuberculosis, Pleural; Tuberculosis, Pulmonary | 1985 |
[Results of chemotherapy in tuberculosis].
Topics: Ambulatory Care; Anti-Bacterial Agents; Antitubercular Agents; Drug Synergism; Ethambutol; Ethionamide; Female; Humans; Isoniazid; Peptides; Pyrazinamide; Thioacetazone; Tuberculosis; Tuberculosis, Pulmonary; Tuberculosis, Urogenital; Viomycin | 1971 |
General considerations in intermittent drug therapy of pulmonary tuberculosis.
Topics: Aminosalicylic Acids; Antitubercular Agents; Clinical Trials as Topic; Ethambutol; Ethionamide; Humans; Isoniazid; Pyrazinamide; Rifampin; Streptomycin; Thioacetazone; Time Factors; Tuberculosis, Pulmonary | 1971 |
Drug reactions. 18. Cutaneous reactions to antituberculous drugs.
Topics: Aminosalicylic Acids; Antitubercular Agents; Capreomycin; Cycloserine; Drug Eruptions; Ethambutol; Ethionamide; Humans; Isoniazid; Isonicotinic Acids; Kanamycin; Pyrazinamide; Rifampin; Skin; Stomatitis; Streptomycin; Thioacetazone; Viomycin | 1972 |
New trends in the chemotherapy of tuberculosis--current aspects.
Topics: Antitubercular Agents; Drug Resistance, Microbial; Drug Therapy, Combination; Ethambutol; Ethionamide; Follow-Up Studies; Humans; Isoniazid; Pyrazinamide; Rifampin; Sputum; Streptomycin; Thioacetazone; Time Factors; Tuberculosis | 1974 |
Leprosy. A preliminary review of the experimental evaluation of drugs for the treatment of leprosy.
Topics: Aminosalicylic Acids; Animals; Anti-Bacterial Agents; Antitubercular Agents; Cycloserine; Ethambutol; Humans; Isoniazid; Leprosy; Mice; Mycobacterium leprae; Phenazines; Pyrazinamide; Streptomycin; Sulfadimethoxine; Sulfides; Thioacetazone; Urea | 1967 |
The impact of chemotherapy on the care of patients with tuberculosis.
Topics: Antitubercular Agents; Aspirin; Bacteriological Techniques; BCG Vaccine; Drug Therapy, Combination; Ethambutol; Hospitalization; Humans; Isoniazid; Length of Stay; Mycobacterium tuberculosis; Outpatient Clinics, Hospital; Pyrazinamide; Rifampin; Streptomycin; Time Factors; Tuberculin Test; Tuberculosis, Pulmonary | 1974 |
[Chemotherapeutic studies on advanced tuberculosis in mice].
Topics: Aminosalicylic Acids; Animals; Antitubercular Agents; Drug Resistance, Microbial; Drug Synergism; Ethambutol; Ethionamide; Isoniazid; Kanamycin; Mice; Models, Biological; Phenazines; Pyrazinamide; Streptomycin; Tuberculosis, Pulmonary; Viomycin | 1965 |
Chemotherapeutics with tuberculostatic action.
Topics: Aminosalicylic Acids; Antitubercular Agents; Catalase; Ethambutol; Ethionamide; Hemin; Humans; Hydrogen Peroxide; Isoniazid; Isonicotinic Acids; Metals; NAD; Pyrazinamide; Structure-Activity Relationship; Thiosemicarbazones | 1971 |
Tuberculosis in Hong Kong ten years later.
Topics: Aminosalicylic Acids; BCG Vaccine; Child, Preschool; China; Cycloserine; Drug Resistance, Microbial; Ethionamide; Health Education; Hong Kong; Hospitalization; Humans; Hypersensitivity; Infant; Infant Mortality; Infant, Newborn; Isoniazid; Pyrazinamide; Racial Groups; Research; Rifampin; Streptomycin; Tuberculosis, Pulmonary | 1973 |
[On the fate of tuberculostatics in macro- and microorganisms].
Topics: Aminosalicylic Acids; Animals; Antitubercular Agents; Cycloserine; Ethionamide; Humans; Isoniazid; Pyrazinamide; Streptomycin | 1967 |
[Experimental chemotherapy of tuberculosis].
Topics: Aminosalicylic Acids; Antitubercular Agents; Cycloserine; Drug Synergism; Ethambutol; Ethionamide; Humans; Isoniazid; Phenylthiourea; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis | 1969 |
[Identification and determination of antitubercular compounds].
Topics: Aminosalicylic Acids; Antitubercular Agents; Chromatography, Ion Exchange; Chromatography, Paper; Chromatography, Thin Layer; Countercurrent Distribution; Cycloserine; Electrophoresis; Ethambutol; Ethionamide; Isoniazid; Methods; Pyrazinamide; Streptomycin | 1970 |
[Antitubercular agents. 2. Specific chemotherapeutic agents].
Topics: Aminosalicylic Acids; Antitubercular Agents; Ethambutol; Ethionamide; Isoniazid; Isonicotinic Acids; Phenylthiourea; Pyrazinamide; Sulfones; Thiosemicarbazones | 1971 |
Chemotherapy of pulmonary tuberculosis.
Topics: Aminosalicylic Acids; Antitubercular Agents; Drug Resistance, Microbial; Ethambutol; Hospitalization; Humans; Isoniazid; Mycobacterium tuberculosis; Pyrazinamide; Streptomycin; Tuberculosis, Pulmonary | 1969 |
[Toxicity of pyrazinamide in antituberculous treatments (author's transl)].
Topics: Chemical and Drug Induced Liver Injury; Diarrhea; Drug Eruptions; Gout; Humans; Isoniazid; Nausea; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis | 1980 |
Treatment of tuberculosis. The Mitchell lecture 1979.
Topics: Animals; Antitubercular Agents; Drug Administration Schedule; Drug Resistance, Microbial; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Pulmonary | 1980 |
Should isoniazid be used in retreatment of tuberculosis despite acquired isoniazid resistance?
Topics: Dose-Response Relationship, Drug; Drug Resistance, Microbial; Drug Therapy, Combination; Ethionamide; Humans; Isoniazid; Mycobacterium tuberculosis; Pyrazinamide; Tuberculosis, Pulmonary | 1981 |
Bacteriologic basis of short-course chemotherapy for tuberculosis.
Topics: Animals; Antitubercular Agents; Drug Resistance, Microbial; Drug Therapy, Combination; Guinea Pigs; Humans; Isoniazid; Mice; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Pulmonary | 1980 |
Tuberculosis.
Topics: Alcohol Drinking; Carrier State; Chemical and Drug Induced Liver Injury; Ethambutol; Humans; Isoniazid; Pyrazinamide; Rifampin; Streptomycin; Tuberculin Test; Tuberculosis, Pulmonary | 1980 |
Drug-induced mitochondrial damage and sideroblastic change.
Topics: Anemia, Sideroblastic; Animals; Bone Marrow; Chloramphenicol; Cycloserine; Erythrocytes; Ethanol; Heme; Humans; Iron; Isoniazid; Lead Poisoning; Mitochondria; Phenacetin; Pyrazinamide; Pyridoxine; Rats | 1980 |
What's new in tuberculosis?
Topics: Aged; Antitubercular Agents; Drug Administration Schedule; Drug Therapy, Combination; Humans; Isoniazid; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Pulmonary | 1981 |
Whither short-course chemotherapy?
Topics: Animals; Drug Administration Schedule; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; Isoniazid; Mice; Pyrazinamide; Rifampin; Sputum; Time Factors; Tuberculosis, Pulmonary | 1981 |
[The therapeutic aspects of urogenital tuberculosis. Apropos of 86 cases].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Antitubercular Agents; Constriction, Pathologic; Endoscopy; Female; Humans; Isoniazid; Male; Middle Aged; Nephrectomy; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Urogenital; Ureter; Ureteral Diseases; Ureteroscopy | 1995 |
Fixed-dose combinations of antituberculous medications to prevent drug resistance.
Topics: Antitubercular Agents; Drug Combinations; Drug Resistance, Microbial; Humans; Isoniazid; Pyrazinamide; Rifampin | 1995 |
Outpatient management of tuberculosis.
Topics: Algorithms; Ambulatory Care; Antitubercular Agents; Drug Administration Schedule; Drug Interactions; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Mass Screening; Population Surveillance; Pyrazinamide; Rifampin; Sensitivity and Specificity; Streptomycin; Tuberculin Test; Tuberculosis, Pulmonary; United States | 1996 |
Feline tuberculosis: a literature review and discussion of 19 cases caused by an unusual mycobacterial variant.
Topics: Animals; Anti-Bacterial Agents; Antitubercular Agents; Cat Diseases; Cats; Diagnosis, Differential; Dihydrostreptomycin Sulfate; Drug Therapy, Combination; Female; Incidence; Isoniazid; Male; Mycobacterium; Mycobacterium bovis; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Skin; Tuberculosis; Tuberculosis, Cutaneous; United Kingdom; Weight Loss | 1996 |
Mechanisms of drug resistance in Mycobacterium tuberculosis.
Topics: Chromosome Mapping; Drug Resistance, Microbial; Isoniazid; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Streptomycin | 1996 |
[Fulminant hepatitis during the therapy for tuberculous meningitis].
Topics: Adult; Antibiotics, Antitubercular; Antitubercular Agents; Drug Therapy, Combination; Female; Hepatic Encephalopathy; Humans; Isoniazid; Pyrazinamide; Rifampin; Tuberculosis, Meningeal | 1996 |
New horizons in the treatment of tuberculosis.
Topics: Animals; Drug Design; Drug Resistance, Microbial; Ethambutol; Humans; Isoniazid; Mycolic Acids; Pyrazinamide; Rifampin; Tuberculosis | 1997 |
[Antitubercular chemotherapy].
Topics: Aged; AIDS-Related Opportunistic Infections; Antitubercular Agents; Child; Clinical Protocols; Drug Combinations; Ethambutol; Follow-Up Studies; HIV Seronegativity; Humans; Isoniazid; Patient Compliance; Patient Education as Topic; Pyrazinamide; Rifampin; Treatment Failure; Tuberculosis; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 1997 |
[Pharyngeal tuberculosis: an analytical study and report of 10 cases].
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Female; Humans; Isoniazid; Male; Middle Aged; Pharyngeal Diseases; Pyrazinamide; Rifampin; Tuberculosis | 1998 |
[Short-course chemotherapy of tuberculosis with pyrazinamide].
Topics: Antibiotics, Antitubercular; Antitubercular Agents; Drug Administration Schedule; Ethambutol; Humans; Isoniazid; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Pulmonary | 1998 |
Molecular genetic basis of antimicrobial agent resistance in Mycobacterium tuberculosis: 1998 update.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antibiotics, Antitubercular; Antitubercular Agents; Cycloserine; Drug Resistance, Multiple; Ethambutol; Ethionamide; Fluoroquinolones; Genes, Bacterial; Isoniazid; Mutation; Mycobacterium tuberculosis; Polymorphism, Genetic; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Multidrug-Resistant; Virulence | 1998 |
Shortening the duration of treatment for cervical tuberculous lymphadenitis.
Topics: Antitubercular Agents; Drug Administration Schedule; Drug Therapy, Combination; Follow-Up Studies; Humans; Isoniazid; Neck; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Lymph Node | 2000 |
Tuberculous peritonitis in patients undergoing continuous ambulatory peritoneal dialysis: case report and review.
Topics: Adult; Antitubercular Agents; Ethambutol; Humans; Isoniazid; Male; Mycobacterium tuberculosis; Peritoneal Dialysis, Continuous Ambulatory; Peritonitis, Tuberculous; Pyrazinamide; Rifampin | 2000 |
Role of individual drugs in the chemotherapy of tuberculosis.
Topics: Antibiotics, Antitubercular; Antitubercular Agents; Drug Administration Schedule; Drug Resistance; Drug Therapy, Combination; Humans; Isoniazid; Microbial Sensitivity Tests; Primary Prevention; Pyrazinamide; Rifampin; Sputum; Time Factors; Treatment Outcome; Tuberculosis | 2000 |
[Molecular mechanisms of multidrug resistance in Mycobacterium tuberculosis].
Topics: Antitubercular Agents; Drug Resistance, Multiple; Ethambutol; Humans; Isoniazid; Mutation; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Multidrug-Resistant | 2000 |
[Effectiveness and problems of PZA-containing 6-month regimen for the treatment of new pulmonary tuberculosis patients].
Topics: Animals; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Pyrazinamide; Rifampin; Risk Factors; Streptomycin; Time Factors; Tuberculosis, Pulmonary | 2001 |
Tubercular laryngeal abscess.
Topics: Abscess; Adult; Antitubercular Agents; Cefotaxime; Diclofenac; Drainage; Ethambutol; Humans; Hydrocortisone; Isoniazid; Laryngoscopy; Male; Pyrazinamide; Rifampin; Tomography, X-Ray Computed; Tuberculosis, Laryngeal | 2001 |
Antitubercular drugs (isoniazid, rifampin and pyrazinamide): hepatobiliary reactions.
Topics: Antitubercular Agents; Biliary Tract Diseases; Chemical and Drug Induced Liver Injury; Humans; Isoniazid; Pyrazinamide; Rifampin | 2001 |
The molecular basis of resistance to isoniazid, rifampin, and pyrazinamide in Mycobacterium tuberculosis.
Topics: Antibiotics, Antitubercular; Antitubercular Agents; Drug Resistance, Microbial; Humans; Isoniazid; Mycobacterium tuberculosis; Pyrazinamide; Rifampin | 2001 |
Tuberculous meningitis: is a 6-month treatment regimen sufficient?
Topics: Adult; Antitubercular Agents; Child; Drug Administration Schedule; Drug Therapy, Combination; Humans; Isoniazid; Pyrazinamide; Recurrence; Rifampin; Tuberculosis, Meningeal | 2001 |
Chemotherapeutic treatment for spinal tuberculosis.
Topics: Adult; Antibiotics, Antitubercular; Antitubercular Agents; Child; Drug Administration Schedule; Female; Humans; Isoniazid; Male; Pyrazinamide; Recurrence; Rifampin; Treatment Outcome; Tuberculosis, Spinal | 2002 |
Primary lingual tuberculosis: a case report with review of literature.
Topics: Adult; Antibiotics, Antitubercular; Antitubercular Agents; Diagnosis, Differential; Ethambutol; Follow-Up Studies; Humans; Isoniazid; Male; Pyrazinamide; Rifampin; Tongue Diseases; Tongue Neoplasms; Tuberculosis, Oral | 2002 |
Cervical lymphadenitis caused by Mycobacterium lentiflavum.
Topics: Abscess; Amoxicillin-Potassium Clavulanate Combination; Humans; Infant; Isoniazid; Lymph Nodes; Male; Mycobacterium; Mycobacterium Infections; Pyrazinamide; Rifampin; Tuberculosis, Lymph Node | 2002 |
[Resistant tuberculosis: a molecular review].
Topics: Antitubercular Agents; Drug Resistance, Multiple, Bacterial; Ethambutol; Humans; Isoniazid; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Multidrug-Resistant | 2002 |
Clinical practice. Latent tuberculosis infection.
Topics: Adult; Antitubercular Agents; Drug Therapy, Combination; Humans; Isoniazid; Male; Practice Guidelines as Topic; Pyrazinamide; Rifampin; Risk Factors; Sensitivity and Specificity; Tuberculin Test; Tuberculosis | 2002 |
Tuberculoma en plaque: a case report.
Topics: Adolescent; Antitubercular Agents; Brain Diseases; Drug Therapy, Combination; Female; Humans; Isoniazid; Pyrazinamide; Rifampin; Tomography, X-Ray Computed; Tuberculoma | 2002 |
[Tuberculous epididymitis caused by Mycobacterium bovis].
Topics: Abscess; Aged; Animal Husbandry; Animals; Anti-Bacterial Agents; Antitubercular Agents; Cattle; Drug Therapy, Combination; Epididymitis; Humans; Isoniazid; Male; Mycobacterium bovis; Occupational Diseases; Pyrazinamide; Rifampin; Scrotum; Tuberculosis, Bovine; Tuberculosis, Male Genital | 2003 |
[COMPLICATIONS OF A METABOLIC AND ENDOCRINE NATURE PRODUCED BY ANTIBACILLARY CHEMOTHERAPY].
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Avitaminosis; Cycloserine; Endocrinology; Ethionamide; Isoniazid; Kanamycin; Metabolic Diseases; Niacin; Niacinamide; Pyrazinamide; Streptomycin; Sulfones; Thiosemicarbazones; Toxicology; Viomycin; Vitamin B 6 Deficiency | 1964 |
[UROGENITAL TUBERCULOSIS: PATHOGENESIS, DIAGNOSIS AND THERAPY. SURVEY OF THE MOST IMPORTANT PUBLICATIONS OF THE LAST YEARS].
Topics: Adrenal Cortex Hormones; Aminosalicylic Acid; Aminosalicylic Acids; Antitubercular Agents; Cycloserine; Ethionamide; Isoniazid; Kanamycin; Mycobacterium tuberculosis; Phenylthiourea; Pyrazinamide; Serologic Tests; Streptomycin; Thiosemicarbazones; Tuberculosis; Tuberculosis, Urogenital; Urine | 1964 |
Safety of rifampin and pyrazinamide for the treatment of latent tuberculosis infection.
Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Antitubercular Agents; Drug Therapy, Combination; Humans; Isoniazid; Pyrazinamide; Randomized Controlled Trials as Topic; Rifampin; Tuberculosis, Pulmonary | 2004 |
Management of spinal tuberculosis--current concepts.
Topics: Antitubercular Agents; Ethambutol; Humans; Isoniazid; Pyrazinamide; Tuberculosis, Spinal | 2004 |
[Procedure in case of suspected mycobacterial infection of lymph nodes of the neck. 2. Therapy].
Topics: Adult; Anti-Bacterial Agents; Antibiotics, Antitubercular; Antitubercular Agents; Disease Notification; Drug Therapy, Combination; Ethambutol; Female; Germany; Humans; Immunocompromised Host; Isoniazid; Male; Mycobacterium Infections; Mycobacterium Infections, Nontuberculous; Patient Isolation; Pyrazinamide; Rifampin; Streptomycin; Time Factors; Tuberculosis, Lymph Node | 2005 |
Rifampicin plus pyrazinamide versus isoniazid for treating latent tuberculosis infection: a meta-analysis.
Topics: Antibiotics, Antitubercular; Antitubercular Agents; Comorbidity; Drug Therapy, Combination; HIV Infections; Humans; Isoniazid; Liver; Pyrazinamide; Randomized Controlled Trials as Topic; Rifampin; Risk Assessment; Tuberculosis | 2006 |
Antituberculosis drugs and hepatotoxicity.
Topics: Antitubercular Agents; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Immunogenetics; Isoniazid; Liver; Pyrazinamide; Rifampin; Risk Factors; Tuberculosis | 2006 |
[Trends in tuberculosis treatment duration].
Topics: Animals; Antibiotics, Antitubercular; Antitubercular Agents; Disease Models, Animal; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Humans; Isoniazid; Mice; Mutation; Mycobacterium tuberculosis; Pyrazinamide; Recurrence; Rifampin; Time Factors; Tuberculosis; Tuberculosis, Multidrug-Resistant | 2006 |
Advances in the treatment of tuberculosis.
Topics: Adamantane; AIDS-Related Opportunistic Infections; Animals; Anti-Bacterial Agents; Antitubercular Agents; Drug Administration Schedule; Drug Resistance, Bacterial; Drug Therapy, Combination; Drugs, Investigational; Ethylenediamines; Extensively Drug-Resistant Tuberculosis; Fluoroquinolones; Humans; Isoniazid; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Pyrazinamide; Rifampin; Treatment Refusal; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 2007 |
Antituberculosis drug-induced hepatotoxicity: concise up-to-date review.
Topics: Antitubercular Agents; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Humans; Incidence; Isoniazid; Liver Diseases; Pyrazinamide; Rifampin; Risk Factors; Tuberculosis | 2008 |
Diffuse pachymeningitis due to Mycobacterium tuberculosis: a case report and review of the literature.
Topics: Adrenal Cortex Hormones; Aged; Antibiotics, Antitubercular; Antitubercular Agents; Ethambutol; Female; Humans; Isoniazid; Meningitis; Mycobacterium tuberculosis; Prednisone; Pyrazinamide; Rifampin; Tuberculosis, Meningeal | 2008 |
Tuberculosis and silicosis: epidemiology, diagnosis and chemoprophylaxis.
Topics: Antibiotics, Antitubercular; Brazil; Humans; Isoniazid; Occupational Exposure; Pyrazinamide; Rifampin; Silicon Dioxide; Silicosis; Silicotuberculosis; Tuberculosis, Pulmonary | 2008 |
Efforts towards the development of new antitubercular agents: potential for thiolactomycin based compounds.
Topics: Animals; Antitubercular Agents; Drug Design; Ethambutol; Isoniazid; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Physiological Phenomena; Pyrazinamide; Rifamycins; Streptomycin; Thiophenes; Tuberculosis; Tuberculosis, Pulmonary | 2008 |
[Use of rifampicin plus pyrazinamide for antituberculosis prophylaxis does not increase the risk of severe hepatotoxicity in HIV patients: meta-analysis of randomized controlled clinical trials].
Topics: Anti-HIV Agents; Antibiotic Prophylaxis; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Drug Synergism; Drug Therapy, Combination; HIV Infections; Humans; Isoniazid; Pyrazinamide; Randomized Controlled Trials as Topic; Risk; Tuberculosis | 2010 |
Tuberculous orchiepididymitis during 1978-2003 period: review of 34 cases and role of 16S rRNA amplification.
Topics: Adult; Aged; Aged, 80 and over; Antitubercular Agents; Combined Modality Therapy; Comorbidity; Epididymitis; Ethambutol; Exudates and Transudates; HIV Infections; Humans; Isoniazid; Male; Middle Aged; Mycobacterium tuberculosis; Orchitis; Prostatitis; Pyrazinamide; Retrospective Studies; Ribotyping; Rifampin; RNA, Ribosomal, 16S; Scrotum; Spain; Tuberculosis, Male Genital; Tuberculosis, Renal; Urine | 2010 |
Pediatric intracranial subdural empyema caused by Mycobacterium tuberculosis--a case report and review of literature.
Topics: Adolescent; Antibiotics, Antitubercular; Craniotomy; Dura Mater; Empyema, Subdural; Humans; Isoniazid; Male; Pyrazinamide; Pyridoxine; Rifampin; Tuberculosis | 2010 |
Bronchiectatic air bronchograms in pulmonary tuberculosis: a case report and literature review.
Topics: Antibiotics, Antitubercular; Antitubercular Agents; Bronchiectasis; Bronchoalveolar Lavage; Bronchoscopy; Diagnosis, Differential; Ethambutol; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Radiography; Rifampin; Tuberculosis, Pulmonary | 2010 |
Primary tuberculosis of the TMJ: presentation of a case and literature review.
Topics: Antitubercular Agents; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Temporomandibular Joint; Temporomandibular Joint Disorders; Treatment Outcome; Tuberculosis, Osteoarticular; Young Adult | 2010 |
Treatment of latent infection with Mycobacterium tuberculosis: update 2010.
Topics: Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Communicable Disease Control; Drug Design; Drug Resistance, Bacterial; Female; HIV Infections; Humans; Isoniazid; Latent Tuberculosis; Male; Mycobacterium tuberculosis; Patient Compliance; Pyrazinamide; Rifampin; Treatment Outcome | 2011 |
Cerebrospinal fluid concentrations of antituberculosis agents in adults and children.
Topics: Adult; Antitubercular Agents; Child; Dose-Response Relationship, Drug; Female; Humans; Isoniazid; Male; Pyrazinamide; Rifampin; Tuberculosis, Meningeal | 2010 |
Best drug treatment for multidrug-resistant and extensively drug-resistant tuberculosis.
Topics: Amikacin; Antitubercular Agents; Capreomycin; Drug Resistance, Multiple; Ethambutol; Extensively Drug-Resistant Tuberculosis; Fluoroquinolones; Humans; Isoniazid; Kanamycin; Levofloxacin; Ofloxacin; Pyrazinamide; Tuberculosis | 2010 |
The chemotherapy of tuberculous meningitis in children and adults.
Topics: Adult; Aminosalicylic Acid; Antibiotics, Antitubercular; Antitubercular Agents; Child; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; History, 18th Century; History, 19th Century; History, 20th Century; History, 21st Century; Humans; Isoniazid; Male; Pyrazinamide; Rifampin; Severity of Illness Index; Streptomycin; Tuberculosis, Meningeal | 2010 |
Surgical treatment of an infant with Bacille Calmette-Guérin osteomyelitis extending across the growth plate.
Topics: Anti-Bacterial Agents; BCG Vaccine; Bone Substitutes; Curettage; Durapatite; Growth Plate; Humans; Infant; Isoniazid; Knee Joint; Male; Meta-Analysis as Topic; Osteomyelitis; Pyrazinamide; Recurrence; Reoperation; Rifampin; Tibia | 2011 |
[Lupus vulgaris caused by Mycobacterium bovis].
Topics: Aged; Antitubercular Agents; Axilla; Drug Therapy, Combination; Humans; Isoniazid; Lupus Vulgaris; Male; Mycobacterium bovis; Pyrazinamide; Rifampin; Tuberculoma; Tuberculosis, Lymph Node; Ultrasonography | 2012 |
[Not just a success story. On the history of tuberculosis treatment].
Topics: Antitubercular Agents; Ethambutol; History, 17th Century; History, 18th Century; History, 19th Century; History, 20th Century; History, Medieval; Humans; Isoniazid; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Streptomycin; Tuberculin; Tuberculosis | 2012 |
Unilateral and painless development of isoniazid induced gynecomastia during re-treatment of pulmonary tuberculosis.
Topics: Adolescent; Anti-Bacterial Agents; Antitubercular Agents; Drug Therapy, Combination; Ethambutol; Gynecomastia; Humans; Isoniazid; Male; Pyrazinamide; Retreatment; Rifampin; Sputum; Streptomycin; Treatment Outcome; Tuberculosis, Pulmonary | 2011 |
Leprosy and tuberculosis co-infection: clinical and immunological report of two cases and review of the literature.
Topics: Adult; Brazil; Coinfection; Female; Humans; Immunity, Cellular; Interferon-gamma; Interleukin-12; Isoniazid; Leprosy; Male; Middle Aged; Prednisone; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Pleural; Tuberculosis, Pulmonary; White People | 2013 |
[Tubercular abscess of the chest wall in the child].
Topics: Abscess; Adolescent; Antitubercular Agents; Biopsy; Combined Modality Therapy; Diagnosis, Differential; Drainage; Drug Therapy, Combination; Ethambutol; Female; Humans; Immunocompetence; Isoniazid; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Sternum; Thoracic Neoplasms; Thoracic Wall; Tomography, X-Ray Computed; Tuberculosis, Cutaneous; Tuberculosis, Osteoarticular | 2013 |
[Pseudotumor form of primary nasopharyngeal tuberculosis: apropos of 2 new cases and review of the literature].
Topics: Antitubercular Agents; Biopsy; Diagnosis, Differential; Drug Therapy, Combination; Humans; Isoniazid; Male; Middle Aged; Nasal Obstruction; Nasopharyngeal Diseases; Nasopharyngeal Neoplasms; Pyrazinamide; Rifampin; Smoking; Tuberculosis; Tuberculosis, Lymph Node; Young Adult | 2013 |
Isolated tuberculous liver abscess in an immunocompetent adult patient: A case report and literature review.
Topics: Aged; Antitubercular Agents; Biopsy; Blood Chemical Analysis; Drug Combinations; Ethambutol; Humans; Isoniazid; Laparotomy; Liver; Liver Abscess; Male; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Tuberculosis | 2016 |
Understanding pharmacokinetics to improve tuberculosis treatment outcome.
Topics: Antitubercular Agents; Diabetes Mellitus; Drug Monitoring; Ethambutol; HIV Infections; Humans; Isoniazid; Microbial Sensitivity Tests; Pyrazinamide; Rifamycins; Treatment Outcome; Tuberculosis; Tuberculosis, Pulmonary | 2014 |
The association between CYP2E1 polymorphisms and hepatotoxicity due to anti-tuberculosis drugs: a meta-analysis.
Topics: Antitubercular Agents; Arylamine N-Acetyltransferase; Cytochrome P-450 CYP2E1; Gene Frequency; Genetic Predisposition to Disease; Genotype; Hepatocytes; Humans; Isoniazid; Liver Failure, Acute; Odds Ratio; Polymorphism, Genetic; Pyrazinamide; Rifampin; Tuberculosis | 2014 |
Antitubercular therapy in patients with cirrhosis: challenges and options.
Topics: Antitubercular Agents; Ethambutol; Humans; Immune System Diseases; Isoniazid; Latent Tuberculosis; Liver; Liver Cirrhosis; Liver Diseases; Liver Failure; Liver Function Tests; Liver Transplantation; Prevalence; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Multidrug-Resistant | 2014 |
Treatment of latent tuberculosis infection: a network meta-analysis.
Topics: Antitubercular Agents; Chemical and Drug Induced Liver Injury; Drug Administration Schedule; Drug Therapy, Combination; Humans; Isoniazid; Latent Tuberculosis; Pyrazinamide; Rifampin | 2014 |
Tuberculous meningitis: advances in diagnosis and treatment.
Topics: Antitubercular Agents; Drug Therapy, Combination; Host-Pathogen Interactions; Humans; Isoniazid; Mycobacterium tuberculosis; Practice Guidelines as Topic; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Meningeal | 2015 |
Tuberculosis Drug Development: History and Evolution of the Mechanism-Based Paradigm.
Topics: Antitubercular Agents; Diarylquinolines; Drug Design; Drug Resistance, Bacterial; Drug Therapy, Combination; Ethambutol; Evolution, Chemical; Female; Humans; Isoniazid; Male; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Tuberculosis; Tuberculosis, Multidrug-Resistant | 2015 |
Clinical research in the treatment of tuberculosis: current status and future prospects.
Topics: Antitubercular Agents; Biomedical Research; Clinical Trials as Topic; Drug Therapy, Combination; Fluoroquinolones; Humans; Isoniazid; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; World Health Organization | 2015 |
Therapeutic drug monitoring in anti-tuberculosis treatment: a systematic review and meta-analysis.
Topics: Antitubercular Agents; Databases, Factual; Dose-Response Relationship, Drug; Drug Monitoring; Ethambutol; Humans; Isoniazid; Pyrazinamide; Randomized Controlled Trials as Topic; Rifampin; Treatment Outcome; Tuberculosis | 2016 |
Optimizing treatment outcome of first-line anti-tuberculosis drugs: the role of therapeutic drug monitoring.
Topics: Antitubercular Agents; Drug Monitoring; Ethambutol; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis | 2016 |
Six-month therapy for abdominal tuberculosis.
Topics: Abdomen; Antitubercular Agents; Drug Administration Schedule; Ethambutol; Humans; Isoniazid; Pyrazinamide; Randomized Controlled Trials as Topic; Recurrence; Rifampin; Time Factors; Tuberculosis, Gastrointestinal | 2016 |
Anti-tuberculosis drug resistance in Ethiopia: systematic review.
Topics: Antitubercular Agents; Drug Resistance, Multiple, Bacterial; Ethambutol; Ethiopia; Humans; Isoniazid; Prevalence; Public Health; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Multidrug-Resistant | 2017 |
Treatment of Latent Tuberculosis Infection: An Updated Network Meta-analysis.
Topics: Adult; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Child; Drug Combinations; Humans; Isoniazid; Latent Tuberculosis; Network Meta-Analysis; Pyrazinamide; Rifampin | 2017 |
A comprehensive review on Primary gallbladder tuberculosis.
Topics: Adolescent; Adult; Antitubercular Agents; Child; Female; Gallbladder Diseases; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Tuberculosis; Young Adult | 2018 |
Development of new drug-regimens against multidrug-resistant tuberculosis.
Topics: Adamantane; Antitubercular Agents; Diarylquinolines; Drug Development; Drug Therapy, Combination; Duration of Therapy; Ethambutol; Ethylenediamines; Humans; Isoniazid; Macrolides; Medication Adherence; Nitroimidazoles; Oxazolidinones; Pyrazinamide; Rifampin; Tuberculosis, Multidrug-Resistant | 2019 |
Pharmacokinetics of First-Line Anti-Tubercular Drugs.
Topics: Age Factors; Antitubercular Agents; Child; Drug Overdose; Ethambutol; Food; Genotype; HIV Infections; Humans; Isoniazid; Malnutrition; Nutritional Status; Polymorphism, Genetic; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis | 2019 |
Severe disseminated tuberculosis in HIV-negative refugees.
Topics: Adolescent; Adult; Antibiotics, Antitubercular; Ethambutol; Fluorine Radioisotopes; HIV Infections; Humans; Isoniazid; Male; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Positron Emission Tomography Computed Tomography; Pyrazinamide; Refugees; Rifampin; Treatment Outcome; Tuberculosis, Pulmonary; Young Adult | 2019 |
A systematic review and meta-analysis of first-line tuberculosis drug concentrations and treatment outcomes.
Topics: Adult; Antitubercular Agents; Case-Control Studies; Humans; Isoniazid; Observational Studies as Topic; Pharmaceutical Preparations; Pyrazinamide; Retrospective Studies; Treatment Outcome; Tuberculosis | 2020 |
Tuberculosis treatment in children: The changing landscape.
Topics: Antitubercular Agents; Child; Drug Therapy, Combination; Duration of Therapy; Ethambutol; Humans; Isoniazid; Pyrazinamide; Rifampin; Tuberculosis; Tuberculosis, Central Nervous System; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 2020 |
Diagnostic Challenges and Dilemmas in Tuberculous Meningitis.
Topics: Adult; Antitubercular Agents; Asthma; Ethambutol; Female; Headache; Hospitalization; Humans; Hydrocephalus; Isoniazid; Leukocytosis; Magnetic Resonance Imaging; Polymerase Chain Reaction; Pyrazinamide; Rifampin; Somalia; Spinal Puncture; Tuberculosis, Meningeal; United States; Vision Disorders | 2020 |
Tuberculosis in 2019.
Topics: Antitubercular Agents; Ethambutol; Health Policy; Humans; India; Isoniazid; Molecular Diagnostic Techniques; Nucleic Acid Amplification Techniques; Polymerase Chain Reaction; Practice Guidelines as Topic; Pulmonologists; Pyrazinamide; Rifampin; Surveys and Questionnaires; Tuberculosis; Tuberculosis, Multidrug-Resistant; World Health Organization | 2020 |
Multiple tuberculomas in an immunocompetent patient and their diagnostic challenge in a high prevalence country: Case report and literature review.
Topics: Antitubercular Agents; Blindness; Brain; Brain Diseases; Cerebellar Ataxia; Dexamethasone; Drug Therapy, Combination; Endemic Diseases; Ethambutol; Female; Glucocorticoids; Humans; Immunocompetence; Isoniazid; Magnetic Resonance Imaging; Nausea; Nystagmus, Pathologic; Peru; Pyrazinamide; Quadriplegia; Rifampin; Tomography, X-Ray Computed; Tuberculoma, Intracranial; Tuberculosis, Pulmonary; Vomiting; Young Adult | 2020 |
Are We There Yet? Short-Course Regimens in TB and HIV: From Prevention to Treatment of Latent to XDR TB.
Topics: Anti-HIV Agents; Antitubercular Agents; Drug Interactions; Extensively Drug-Resistant Tuberculosis; HIV Infections; Humans; Isoniazid; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 2020 |
Thinking Outside the Lungs: A Case of Disseminated Abdominal Tuberculosis.
Topics: Antitubercular Agents; Female; Humans; Isoniazid; Lung; Middle Aged; Pyrazinamide; Rifampin | 2020 |
Development of physiologically-based pharmacokinetic models for standard of care and newer tuberculosis drugs.
Topics: Antitubercular Agents; Humans; Isoniazid; Pyrazinamide; Standard of Care; Tuberculosis | 2021 |
Tuberculosis drug discovery: Progression and future interventions in the wake of emerging resistance.
Topics: Antitubercular Agents; Diarylquinolines; Drug Therapy, Combination; Ethambutol; Extensively Drug-Resistant Tuberculosis; Humans; Isoniazid; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Pyrazinamide; Rifampin | 2022 |
Global estimates and determinants of antituberculosis drug pharmacokinetics in children and adolescents: a systematic review and individual patient data meta-analysis.
Topics: Adolescent; Antitubercular Agents; Child; Child, Preschool; Ethambutol; Humans; Isoniazid; Pyrazinamide; Rifampin | 2023 |
Effectiveness and Pharmacokinetic Exposures of First-Line Drugs Used to Treat Drug-Susceptible Tuberculosis in Children: A Systematic Review and Meta-Analysis.
Topics: Adolescent; Adult; Antitubercular Agents; Child; Ethambutol; HIV; HIV Infections; Humans; Isoniazid; Pyrazinamide; Rifampin; Tuberculosis | 2023 |
Antitubercular drugs induced liver injury: an updated insight into molecular mechanisms.
Topics: Antitubercular Agents; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liver Injury, Chronic; Humans; Isoniazid; Pyrazinamide; Rifampin | 2023 |
[Treatment of tuberculosis: what is new?]
Topics: Antitubercular Agents; Humans; Isoniazid; Moxifloxacin; Pyrazinamide; Tuberculosis; Tuberculosis, Multidrug-Resistant | 2023 |
250 trial(s) available for pyrazinamide and isoniazid
| Article | Year |
|---|---|
Short-course treatment in pulmonary tuberculosis.
Topics: Adolescent; Adult; Africa, Eastern; Antitubercular Agents; Humans; Isoniazid; Middle Aged; Pyrazinamide; Rifampin; Streptomycin; Thioacetazone; Time Factors; Tuberculosis, Pulmonary | 1975 |
Short-course chemotherapy in pulmonary tuberculosis.
Topics: Clinical Trials as Topic; Developing Countries; Drug Therapy, Combination; Humans; Isoniazid; Pyrazinamide; Rifampin; Streptomycin; Thioacetazone; Time Factors; Tuberculosis, Pulmonary | 1977 |
Controlled clinical trial of four short-course regimens of chemotherapy for two durations in the treatment of pulmonary tuberculosis: first report: Third East African/British Medical Research Councils study.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Clinical Trials as Topic; Drug Administration Schedule; Drug Resistance; Drug Therapy, Combination; Female; Humans; Isoniazid; Kenya; Male; Middle Aged; Pyrazinamide; Recurrence; Rifampin; Streptomycin; Tanzania; Thioacetazone; Time Factors; Tuberculosis, Pulmonary; Uganda; Zambia | 1978 |
Controlled clinical trial of five short-course (4-month) chemotherapy regimens in pulmonary tuberculosis. First report of 4th study. East African and British Medical Research Councils.
Topics: Adolescent; Adult; Africa, Eastern; Aged; Clinical Trials as Topic; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Isoniazid; Male; Middle Aged; Mycobacterium tuberculosis; Pyrazinamide; Random Allocation; Rifampin; Streptomycin; Time Factors; Tuberculosis, Pulmonary; Zambia | 1978 |
Sputum-smear-negative pulmonary tuberculosis: controlled trial of 3-month and 2-month regimens of chemotherapy.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Drug Therapy, Combination; Humans; Isoniazid; Male; Middle Aged; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Sputum; Streptomycin; Time Factors; Tuberculosis, Pulmonary | 1979 |
Controlled trial of 6-month and 8-month regimens in the treatment of pulmonary tuberculosis. First report.
Topics: Adolescent; Adult; Antitubercular Agents; Clinical Trials as Topic; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Ethambutol; Humans; Infant, Newborn; Isoniazid; Mycobacterium tuberculosis; Pyrazinamide; Random Allocation; Rifampin; Streptomycin; Time Factors; Tuberculosis, Pulmonary | 1978 |
The hepatic toxicity of antituberculosis regimens containing isoniazid, rifampicin and pyrazinamide.
Topics: Acetylation; Adolescent; Adult; Aged; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Liver Function Tests; Middle Aged; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 1978 |
Clinical trial of six-month and four-month regimens of chemotherapy in the treatment of pulmonary tuberculosis.
Topics: Adolescent; Adult; Alanine Transaminase; Antitubercular Agents; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Recurrence; Rifampin; Sputum; Streptomycin; Tuberculosis, Pulmonary | 1979 |
[Controlled trial of 6 to 8 month chemotherapeutic regimens in the treatment of pulmonary tuberculosis. A study of Hong Kong Chest Service/British Medical Research Council/].
Topics: Antitubercular Agents; Clinical Trials as Topic; Drug Therapy, Combination; Ethambutol; Hong Kong; Humans; Isoniazid; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Pulmonary | 1978 |
[Short term chemotherapy of tuberculosis. Evaluation of an 18-week-long treatment including pyrazinamide (preliminary results)].
Topics: Antitubercular Agents; Clinical Trials as Topic; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Pulmonary | 1978 |
Controlled clinical trial of four 6-month regimens of chemotherapy for pulmonary tuberculosis. Second report. Second East African/British Medical Research Council Study.
Topics: Adolescent; Clinical Trials as Topic; Drug Therapy, Combination; Follow-Up Studies; Humans; Isoniazid; Pyrazinamide; Rifamycins; Streptomycin; Time Factors; Tuberculosis, Pulmonary | 1976 |
Controlled trial of 6- and 9-month regimens of daily and intermittent streptomycin plus isoniazid plus pyrazinamide for pulmonary tuberculosis in Hong Kong.
Topics: Adolescent; Adult; Clinical Trials as Topic; Drug Combinations; Drug Resistance, Microbial; Female; Hong Kong; Humans; Isoniazid; Male; Pyrazinamide; Recurrence; Sputum; Streptomycin; Time Factors; Tuberculosis, Pulmonary | 1975 |
Intensive short course chemotherapy for treatment of Greek children with tuberculosis.
Topics: Anti-Bacterial Agents; Child; Child, Preschool; Drug Administration Schedule; Drug Therapy, Combination; Female; Greece; Humans; Infant; Isoniazid; Male; Prospective Studies; Pyrazinamide; Rifampin; Tuberculosis | 1992 |
Six-months versus nine-months chemotherapy for tuberculosis of lymph nodes: preliminary results. British Thoracic Society Research Committee.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antitubercular Agents; Drug Administration Schedule; Ethambutol; Humans; Isoniazid; Middle Aged; Pyrazinamide; Rifampin; Time Factors; Tuberculosis, Lymph Node | 1992 |
Comparative efficacy of drug regimens in skin tuberculosis.
Topics: Adolescent; Adult; Antitubercular Agents; Child; Drug Administration Schedule; Drug Therapy, Combination; Humans; Isoniazid; Pyrazinamide; Rifampin; Thioacetazone; Tuberculosis, Cutaneous | 1991 |
Controlled trial of 2, 4, and 6 months of pyrazinamide in 6-month, three-times-weekly regimens for smear-positive pulmonary tuberculosis, including an assessment of a combined preparation of isoniazid, rifampin, and pyrazinamide. Results at 30 months. Hon
Topics: Adolescent; Adult; Drug Administration Schedule; Drug Combinations; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Humans; Isoniazid; Male; Middle Aged; Mycobacterium tuberculosis; Pyrazinamide; Recurrence; Rifampin; Sputum; Streptomycin; Tuberculosis, Pulmonary | 1991 |
Assessment of a daily combined preparation of isoniazid, rifampin, and pyrazinamide in a controlled trial of three 6-month regimens for smear-positive pulmonary tuberculosis. Singapore Tuberculosis Service/British Medical Research Council.
Topics: Adolescent; Adult; Drug Combinations; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Humans; Isoniazid; Male; Middle Aged; Mycobacterium tuberculosis; Patient Compliance; Pyrazinamide; Recurrence; Rifampin; Sputum; Streptomycin; Tuberculosis, Pulmonary | 1991 |
Short-course chemotherapy for pulmonary tuberculosis under routine programme conditions: a comparison of regimens of 28 and 36 weeks duration in Algeria. Algerian Working Group/British Medical Research Council Cooperative Study.
Topics: Adolescent; Adult; Aged; Algeria; Antitubercular Agents; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Streptomycin; Time Factors; Tuberculosis, Pulmonary | 1991 |
[A therapeutic trial of a combination of 3 essential drugs in a short course of chemotherapy in tuberculosis. Results 6 months after the end of treatment].
Topics: Drug Combinations; Drug Resistance, Microbial; Follow-Up Studies; Humans; Isoniazid; Mycobacterium tuberculosis; Pyrazinamide; Random Allocation; Rifampin; Tuberculosis, Pulmonary | 1990 |
Five year results of a 3-month and two 5-month regimens for the treatment of sputum-positive pulmonary tuberculosis in south India.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Drug Administration Schedule; Drug Resistance, Microbial; Follow-Up Studies; Humans; Isoniazid; Middle Aged; Mycobacterium tuberculosis; Pyrazinamide; Recurrence; Rifampin; Sputum; Streptomycin; Tuberculosis, Pulmonary | 1990 |
USPHS Tuberculosis Short-Course Chemotherapy Trial 21: effectiveness, toxicity, and acceptability. The report of final results.
Topics: Adult; Antitubercular Agents; Centers for Disease Control and Prevention, U.S.; Data Interpretation, Statistical; Drug Administration Schedule; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Multicenter Studies as Topic; Patient Compliance; Proportional Hazards Models; Pyrazinamide; Randomized Controlled Trials as Topic; Recurrence; Rifampin; Sputum; Survival Rate; Tuberculosis, Pulmonary; United States | 1990 |
Short-course chemotherapy for pulmonary tuberculosis with a rifampicin-isoniazid-pyrazinamide combination tablet.
Topics: Adult; Antitubercular Agents; Drug Combinations; Drug Therapy, Combination; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Randomized Controlled Trials as Topic; Rifampin; Streptomycin; Tablets; Tuberculosis, Pulmonary | 1990 |
[Tisamide in the complex treatment of tuberculosis].
Topics: Adult; Drug Therapy, Combination; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Pulmonary | 1990 |
A randomized trial of fully intermittent vs. daily followed by intermittent short course chemotherapy for childhood tuberculosis.
Topics: Adolescent; Antitubercular Agents; Child; Child, Preschool; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Infant; Isoniazid; Male; Patient Compliance; Pyrazinamide; Rifampin; Tuberculosis; Tuberculosis, Lymph Node; Tuberculosis, Pulmonary | 1990 |
Six-month combination chemotherapy for cervical tuberculous lymphadenitis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antitubercular Agents; Child; Drug Therapy, Combination; Female; Humans; Isoniazid; Male; Middle Aged; Prospective Studies; Pyrazinamide; Reoperation; Rifampin; Streptomycin; Tuberculosis, Lymph Node | 1990 |
Pyrazinamide as a part of combination therapy for BL and LL patients--a preliminary report.
Topics: Adolescent; Adult; Animals; Clofazimine; Dapsone; Drug Therapy, Combination; Female; Humans; Isoniazid; Leprosy; Male; Mice; Middle Aged; Muscle, Smooth; Pyrazinamide; Rifampin; Scrotum; Skin; Thioacetazone | 1988 |
Intracranial tuberculomas. An assessment of a therapeutic 4-drug trial in 35 children.
Topics: Adolescent; Antitubercular Agents; Brain Diseases; Child; Child, Preschool; Combined Modality Therapy; Ethambutol; Female; Humans; Infant; Isoniazid; Male; Pyrazinamide; Retrospective Studies; Rifampin; Tomography, X-Ray Computed; Tuberculoma | 1989 |
Acceptability, compliance, and adverse reactions when isoniazid, rifampin, and pyrazinamide are given as a combined formulation or separately during three-times-weekly antituberculosis chemotherapy.
Topics: Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Humans; Isoniazid; Patient Compliance; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 1989 |
[A controlled survey comparing 2 short-term therapeutic regimes in lymph node tuberculosis].
Topics: Adolescent; Adult; Antitubercular Agents; Child; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Streptomycin; Time Factors; Tuberculosis, Lymph Node | 1989 |
[Therapeutic trial of a combination of isoniazid, rifampicin and pyrazinamide in the first 2 months of treatment of pulmonary tuberculosis].
Topics: Adolescent; Adult; Antitubercular Agents; Clinical Trials as Topic; Drug Combinations; Drug Therapy, Combination; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Random Allocation; Rifampin; Tuberculosis, Pulmonary | 1989 |
A controlled trial of 3-month, 4-month, and 6-month regimens of chemotherapy for sputum-smear-negative pulmonary tuberculosis. Results at 5 years. Hong Kong Chest Service/Tuberculosis Research Centre, Madras/British Medical Research Council.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Clinical Trials as Topic; Drug Administration Schedule; Drug Therapy, Combination; Female; Hong Kong; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Random Allocation; Rifampin; Sputum; Streptomycin; Tuberculosis, Pulmonary | 1989 |
[Short-term therapy of lung tuberculosis using a fixed combination of isoniazid, rifampicin and pyrazinamide. Results after 2 years].
Topics: Adult; Antitubercular Agents; Drug Combinations; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Multicenter Studies as Topic; Patient Compliance; Prospective Studies; Pyrazinamide; Recurrence; Rifampin; Time Factors; Tuberculosis, Pulmonary | 1989 |
Clinical trial of three 6-month regimens of chemotherapy given intermittently in the continuation phase in the treatment of pulmonary tuberculosis. Singapore Tuberculosis Service/British Medical Research Council.
Topics: Adolescent; Adult; Antitubercular Agents; Clinical Trials as Topic; Drug Administration Schedule; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Pulmonary | 1985 |
Long-term follow-up of a clinical trial of six-month and four-month regimens of chemotherapy in the treatment of pulmonary tuberculosis. Singapore Tuberculosis Service/British Medical Research Council.
Topics: Adolescent; Adult; Antibiotics, Antitubercular; Clinical Trials as Topic; Follow-Up Studies; Humans; Isoniazid; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis | 1986 |
Five-year follow-up of a clinical trial of three 6-month regimens of chemotherapy given intermittently in the continuation phase in the treatment of pulmonary tuberculosis. Singapore Tuberculosis Service/British Medical Research Council.
Topics: Antitubercular Agents; Drug Administration Schedule; Drug Resistance, Microbial; Drug Therapy, Combination; Follow-Up Studies; Humans; Isoniazid; Mycobacterium tuberculosis; Pyrazinamide; Recurrence; Rifampin; Streptomycin; Tuberculosis, Pulmonary | 1988 |
Adrenal function in tuberculosis.
Topics: Acute Disease; Adolescent; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aged; Child; Child, Preschool; Ethambutol; Female; Humans; Hydrocortisone; Infant; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Pulmonary | 1986 |
Controlled clinical trial of a regimen of two durations for the treatment of isoniazid resistant pulmonary tuberculosis.
Topics: Adolescent; Adult; Clinical Trials as Topic; Drug Resistance, Microbial; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Pyrazinamide; Random Allocation; Rifampin; Streptomycin; Tuberculosis, Pulmonary | 1988 |
Pulmonary tuberculosis treated with isoprodian and rifampicin or pyrazinamide.
Topics: Adult; Aged; Antitubercular Agents; Clinical Trials as Topic; Dapsone; Drug Combinations; Drug Therapy, Combination; Female; Humans; Isoniazid; Male; Middle Aged; Patient Compliance; Prothionamide; Pyrazinamide; Radiography; Recurrence; Rifampin; Sputum; Tuberculosis, Pulmonary | 1987 |
Short-course chemotherapy of pulmonary tuberculosis in pneumoconiotic patients.
Topics: Adult; Aged; Antitubercular Agents; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Isoniazid; Middle Aged; Pneumoconiosis; Prospective Studies; Pyrazinamide; Recurrence; Rifampin; Streptomycin; Time Factors; Tuberculosis, Pulmonary | 1987 |
[Results of a shortened (6 months) schedule of treatment of pulmonary tuberculosis using INH, RMP and PZA].
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Clinical Trials as Topic; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Time Factors; Tuberculosis, Pulmonary | 1987 |
United States Public Health Service Tuberculosis Therapy Trial 21: preliminary results of an evaluation of a combination tablet of isoniazid, rifampin and pyrazinamide.
Topics: Clinical Trials as Topic; Drug Combinations; Female; Humans; Isoniazid; Male; Patient Compliance; Pyrazinamide; Random Allocation; Rifampin; Tuberculosis, Pulmonary | 1987 |
Short-course tuberculosis chemotherapy studies conducted in Poland during the past decade.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Clinical Trials as Topic; Drug Administration Schedule; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Recurrence; Rifampin; Streptomycin; Tuberculosis, Pulmonary | 1986 |
Controlled clinical trial of 4 short-course regimens of chemotherapy (three 6-month and one 8-month) for pulmonary tuberculosis: final report. East and Central African/British Medical Research Council Fifth Collaborative Study.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Clinical Trials as Topic; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Random Allocation; Rifampin; Streptomycin; Tuberculosis, Pulmonary | 1986 |
A controlled clinical trial of 3- and 5-month regimens in the treatment of sputum-positive pulmonary tuberculosis in South India. Tuberculosis Research Centre, Madras, and National Tuberculosis Institute, Bangalore.
Topics: Adolescent; Adult; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Dizziness; Drug Administration Schedule; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; India; Isoniazid; Joint Diseases; Male; Middle Aged; Pyrazinamide; Recurrence; Rifampin; Streptomycin; Time Factors; Tuberculosis, Pulmonary | 1986 |
[Daily ultrashort chemotherapy and intermittent short-term chemotherapy with 4 drugs of communicable pulmonary tuberculosis treated for the first time. Results of a cooperative multicenter study].
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Clinical Trials as Topic; Drug Administration Schedule; Drug Therapy, Combination; Humans; Isoniazid; Middle Aged; Pyrazinamide; Random Allocation; Rifampin; Streptomycin; Tuberculosis, Pulmonary | 1986 |
Controlled clinical trial of three short-course regimens of chemotherapy for pulmonary tuberculosis in Nigeria--a preliminary report.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Clinical Trials as Topic; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Female; Humans; Isoniazid; Male; Middle Aged; Nigeria; Pyrazinamide; Rifampin; Sputum; Streptomycin; Tuberculosis, Pulmonary | 1986 |
Three chemotherapy studies of tuberculous meningitis in children.
Topics: Antitubercular Agents; Child; Child, Preschool; Drug Therapy, Combination; Ethambutol; Female; Humans; India; Infant; Isoniazid; Male; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Meningeal | 1986 |
Controlled clinical trial of two 6-month regimens of chemotherapy in the treatment of pulmonary tuberculosis. Tanzania/British Medical Research Council Study.
Topics: Adolescent; Adult; Clinical Trials as Topic; Drug Resistance, Microbial; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Recurrence; Rifampin; Streptomycin; Tanzania; Tuberculosis, Pulmonary | 1985 |
Operational evaluation of treatment for tuberculosis. Results of 8- and 12-month regimens in Peru.
Topics: Adolescent; Adult; Antitubercular Agents; Child; Child, Preschool; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Infant; Infant, Newborn; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Streptomycin; Time Factors; Tuberculosis, Pulmonary | 1985 |
[Which is the best drug combination for the short-term therapy of tuberculosis? A prospective randomized study with 190 patients].
Topics: Adult; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Patient Compliance; Prospective Studies; Pyrazinamide; Random Allocation; Rifampin; Tuberculosis, Pulmonary | 1985 |
[Controlled study comparing 3 daily chemotherapy regimens for six months in pulmonary tuberculosis in routine practice in Algiers. Results at 30 months].
Topics: Antitubercular Agents; Clinical Trials as Topic; Drug Resistance, Microbial; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 1985 |
General considerations in intermittent drug therapy of pulmonary tuberculosis.
Topics: Aminosalicylic Acids; Antitubercular Agents; Clinical Trials as Topic; Ethambutol; Ethionamide; Humans; Isoniazid; Pyrazinamide; Rifampin; Streptomycin; Thioacetazone; Time Factors; Tuberculosis, Pulmonary | 1971 |
Controlled clinical trial of short-course (6-month) regimens of chemotherapy for treatment of pulmonary tuberculosis.
Topics: Administration, Oral; Adolescent; Adult; Antitubercular Agents; Clinical Trials as Topic; Drug Combinations; Drug Resistance, Microbial; Evaluation Studies as Topic; Female; Humans; Injections, Intramuscular; Isoniazid; Male; Microbial Sensitivity Tests; Middle Aged; Pyrazinamide; Radiography; Recurrence; Rifampin; Sputum; Streptomycin; Thioacetazone; Time Factors; Tuberculosis, Pulmonary | 1972 |
Controlled clinical trial of four short-course (6-month) regimens of chemotherapy for treatment of pulmonary tuberculosis. Second report.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Drug Resistance, Microbial; Female; Humans; Isoniazid; Male; Middle Aged; Mycobacterium tuberculosis; Pyrazinamide; Radiography; Rifamycins; Streptomycin; Thioacetazone; Time Factors; Tuberculosis, Pulmonary | 1973 |
Controlled clinical trial of four short-course (6-month) regimens of chemotherapy for treatment of pulmonary tuberculosis. Third report. East African-British Medical Research Councils.
Topics: Adolescent; Adult; Africa, Eastern; Clinical Trials as Topic; Drug Combinations; Drug Evaluation; Drug Resistance, Microbial; Drug Therapy, Combination; Follow-Up Studies; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrazinamide; Recurrence; Rifampin; Streptomycin; Thioacetazone; Time Factors; Tuberculosis, Pulmonary | 1974 |
Interaction aspects of antimycobacterial drugs in the chemotherapy of tuberculosis. I. Role of individual antituberculous drugs in drug regimens used in the chemotherapy of human tuberculosis.
Topics: Aminosalicylic Acids; Antitubercular Agents; Clinical Trials as Topic; Cycloserine; Drug Evaluation; Drug Therapy, Combination; Ethambutol; Ethionamide; Humans; Isoniazid; Pyrazinamide; Rifampin; Streptomycin; Thioacetazone; Tuberculosis, Pulmonary | 1974 |
Controlled clinical trial of four short-course (6-month) regimens of chemotherapy for treatment of pulmonary tuberculosis.
Topics: Administration, Oral; Adolescent; Adult; Africa; Clinical Trials as Topic; Drug Combinations; Drug Evaluation; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Humans; Injections, Intramuscular; Isoniazid; Male; Mycobacterium tuberculosis; Pyrazinamide; Recurrence; Rifampin; Sputum; Streptomycin; Thioacetazone; Time Factors; Tuberculosis, Pulmonary | 1974 |
[Short-term treatment of pulmonary tuberculosis].
Topics: Adolescent; Antitubercular Agents; Clinical Trials as Topic; Drug Therapy, Combination; Evaluation Studies as Topic; Humans; Isoniazid; Pyrazinamide; Rifampin; Streptomycin; Thioacetazone; Time Factors; Tuberculosis, Pulmonary | 1974 |
Evaluation of results of chemotherapy in tuberculosis with special consideration of ethambutol.
Topics: Aminosalicylic Acids; Clinical Trials as Topic; Cycloserine; Drug Combinations; Electronic Data Processing; Ethambutol; Ethionamide; Evaluation Studies as Topic; Humans; Isoniazid; Phenylthiourea; Pyrazinamide; Streptomycin; Thiosemicarbazones; Tuberculosis, Pulmonary; Viomycin | 1970 |
Ethambutol in the initial treatment of pulmonary tuberculosis. U.S. Public Health Service tuberculosis therapy trials.
Topics: Adolescent; Adult; Aminosalicylic Acids; Clinical Trials as Topic; Ethambutol; Evaluation Studies as Topic; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Radiography; Sputum; Tuberculosis, Pulmonary; Visual Acuity | 1973 |
Clinical experience of intermittent treatment in the United Kingdom.
Topics: Aminosalicylic Acids; Clinical Trials as Topic; Humans; Isoniazid; Pyrazinamide; Streptomycin; Tuberculosis, Pulmonary; United Kingdom | 1968 |
A comparison of regimens of ethionamide, pyrazinamide and cycloserine in re-treatment of patients with pulmonary tuberculosis.
Topics: Clinical Trials as Topic; Cycloserine; Ethionamide; Humans; Isoniazid; Prospective Studies; Pyrazinamide; Tuberculosis, Pulmonary | 1968 |
A controlled comparison of four regimens of streptomycin plus pyrazinamide in the retreatment of pulmonary tuberculosis.
Topics: Adolescent; Adult; Aspartate Aminotransferases; Clinical Trials as Topic; Drug Resistance, Microbial; Female; Humans; Injections, Intramuscular; Isoniazid; Male; Mathematics; Middle Aged; Pyrazinamide; Radiography; Sex Factors; Sputum; Streptomycin; Tuberculosis, Pulmonary | 1969 |
Controlled clinical trials with Isoxyl.
Topics: Clinical Trials as Topic; Cycloserine; Drug Combinations; Drug Synergism; Ethionamide; Evaluation Studies as Topic; Humans; Isoniazid; Phenylthiourea; Pyrazinamide; Tuberculosis, Pulmonary | 1970 |
Madras study of supervised once-weekly chemotherapy in the treatment of pulmonary tuberculosis: laboratory aspects.
Topics: Clinical Trials as Topic; Drug Resistance, Microbial; Drug Synergism; Humans; India; Isoniazid; Mycobacterium tuberculosis; Pyrazinamide; Streptomycin; Tuberculosis, Pulmonary | 1968 |
A controlled comparison of a twice-weekly and three once-weekly regimens in the initial treatment of pulmonary tuberculosis.
Topics: Adolescent; Adult; Child; Humans; India; Isoniazid; Microbial Sensitivity Tests; Middle Aged; Pyrazinamide; Streptomycin; Tuberculosis, Pulmonary | 1970 |
Controlled clinical trial of four short-course regimens of chemotherapy for two durations in the treatment of pulmonary tuberculosis. Second report. Third East African/British Medical Research Council Study.
Topics: Adolescent; Adult; Antibiotics, Antitubercular; Clinical Trials as Topic; Drug Administration Schedule; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; Isoniazid; Pyrazinamide; Random Allocation; Rifampin; Streptomycin; Thioacetazone; Time Factors; Tuberculosis, Pulmonary | 1980 |
Comparison of a conventional and an initial 2-month intensive drug regimen for treating pulmonary tuberculosis in Swaziland.
Topics: Adult; Antitubercular Agents; Clinical Trials as Topic; Drug Administration Schedule; Drug Therapy, Combination; Eswatini; Female; Humans; Isoniazid; Male; Middle Aged; Patient Compliance; Pyrazinamide; Recurrence; Rifampin; Streptomycin; Thioacetazone; Time Factors; Tuberculosis, Pulmonary | 1984 |
Study of chemotherapy regimens of 5 and 7 months' duration and the role of corticosteroids in the treatment of sputum-positive patients with pulmonary tuberculosis in South India.
Topics: Adult; Antitubercular Agents; Clinical Trials as Topic; Drug Administration Schedule; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Humans; Isoniazid; Male; Middle Aged; Prednisolone; Pyrazinamide; Random Allocation; Rifampin; Sputum; Streptomycin; Tuberculosis, Pulmonary | 1983 |
Controlled clinical trial of 4 short-couse regimens of chemotherapy (three 6-month and one 8-month) for pulmonary tuberculosis.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Clinical Trials as Topic; Drug Administration Schedule; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Random Allocation; Rifampin; Streptomycin; Tuberculosis, Pulmonary | 1983 |
[Short-term chemotherapy of tuberculosis. Cooperative French trial].
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Clinical Trials as Topic; Drug Therapy, Combination; Ethambutol; Female; Follow-Up Studies; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Pulmonary | 1983 |
Controlled clinical trial comparing a 6-month and a 12-month regimen in the treatment of pulmonary tuberculosis in the Algerian Sahara. Algerian working group/British Medical Research Council cooperative study.
Topics: Adolescent; Adult; Algeria; Antitubercular Agents; Clinical Trials as Topic; Drug Administration Schedule; Drug Therapy, Combination; Ethambutol; Female; Hospitalization; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Rural Population; Streptomycin; Tuberculosis, Pulmonary | 1984 |
A controlled trial of 6 months' chemotherapy in pulmonary tuberculosis. Final report: results during the 36 months after the end of chemotherapy and beyond. British Thoracic Society.
Topics: Antitubercular Agents; Clinical Trials as Topic; Drug Administration Schedule; Drug Therapy, Combination; Ethambutol; Follow-Up Studies; Humans; Isoniazid; Pyrazinamide; Recurrence; Rifampin; Streptomycin; Tuberculosis, Pulmonary | 1984 |
Supervised six-months treatment of newly diagnosed pulmonary tuberculosis using isoniazid, rifampin, and pyrazinamide with and without streptomycin.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Recurrence; Rifampin; Streptomycin; Time Factors; Tuberculosis, Pulmonary | 1984 |
[Pyrazinamide versus ethambutol in short-term therapy of lung tuberculosis. A randomized study].
Topics: Adult; Aged; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Middle Aged; Pyrazinamide; Random Allocation; Rifampin; Time Factors; Tuberculosis, Pulmonary | 1983 |
A controlled trial of six months chemotherapy in pulmonary tuberculosis. Second report: results during the 24 months after the end of chemotherapy. British Thoracic Association.
Topics: Antitubercular Agents; Clinical Trials as Topic; Drug Administration Schedule; Drug Therapy, Combination; Ethambutol; Follow-Up Studies; Humans; Isoniazid; Pyrazinamide; Recurrence; Rifampin; Streptomycin; Time Factors; Tuberculosis, Pulmonary | 1982 |
[Short-term chemotherapy of pulmonary tuberculosis. Bacteriologic results].
Topics: Adolescent; Adult; Clinical Trials as Topic; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Pyrazinamide; Rifampin; Sputum; Time Factors; Tuberculosis, Pulmonary | 1980 |
[Controlled trial of isoniazid.rifampicin.ethambutol regimen and isoniazid.rifampicin.pyrazinamide regimen in the primary chemotherapy for pulmonary tuberculosis (author's transl)].
Topics: Adult; Antitubercular Agents; Clinical Trials as Topic; Drug Administration Schedule; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 1980 |
Side-effects of drug regimens used in short-course chemotherapy for pulmonary tuberculosis. A controlled clinical study.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Middle Aged; Pyrazinamide; Random Allocation; Rifampin; Streptomycin; Time Factors; Tuberculosis, Pulmonary | 1980 |
Controlled clinical trial of five short-course (4-month) chemotherapy regimens in pulmonary tuberculosis. Second report of the 4th study. East African/British Medical Research Councils Study.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Clinical Trials as Topic; Drug Administration Schedule; Drug Therapy, Combination; Humans; Isoniazid; Middle Aged; Pyrazinamide; Random Allocation; Recurrence; Rifampin; Streptomycin; Tuberculosis, Pulmonary | 1981 |
A controlled trial of six months chemotherapy in pulmonary tuberculosis. First Report: results during chemotherapy. British Thoracic Association.
Topics: Adolescent; Adult; Clinical Trials as Topic; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Pulmonary | 1981 |
Clinical trial of six-month and four-month regimens of chemotherapy in the treatment of pulmonary tuberculosis: the results up to 30 months.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Clinical Trials as Topic; Drug Administration Schedule; Drug Therapy, Combination; Humans; Isoniazid; Middle Aged; Pyrazinamide; Random Allocation; Rifampin; Streptomycin; Time Factors; Tuberculosis, Pulmonary | 1981 |
BTA short-course chemotherapy studies.
Topics: Clinical Trials as Topic; Ethambutol; Female; Hepatitis; Humans; Isoniazid; Liver Function Tests; Male; Pyrazinamide; Rifampin; Streptomycin; Time Factors; Tuberculosis, Pulmonary; United Kingdom | 1981 |
A study of the characteristics and course of sputum smear-negative pulmonary tuberculosis.
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Radiography; Rifampin; Sputum; Streptomycin; Tuberculosis, Pulmonary | 1981 |
Short-course chemotherapy for pulmonary tuberculosis. A 100-day interrupted regimen.
Topics: Adult; Antibiotics, Antitubercular; Clinical Trials as Topic; Drug Administration Schedule; Drug Combinations; Follow-Up Studies; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Recurrence; Rifampin; Streptomycin; Tuberculosis, Pulmonary | 1981 |
Chemotherapy for tuberculosis today.
Topics: Antitubercular Agents; Clinical Trials as Topic; Ethambutol; Humans; Isoniazid; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 1982 |
[Comparative study of the treatment of pulmonary tuberculosis with isoprodian and pyrazinamide as well as isoprodian and rifampicin].
Topics: Adult; Aged; Antitubercular Agents; Dapsone; Drug Combinations; Drug Therapy, Combination; Humans; Isoniazid; Isonicotinic Acids; Male; Middle Aged; Prothionamide; Pyrazinamide; Radiography; Rifampin; Sputum; Time Factors; Tuberculosis, Pulmonary | 1982 |
[Clinical trial of a combination of three drugs in fixed proportions in the treatment of tuberculosis. Groupe de Travail sur la Chimiothérapie de la Tuberculose].
Topics: Adolescent; Adult; Anti-Bacterial Agents; Antitubercular Agents; Drug Therapy, Combination; Drug Tolerance; Female; Humans; Isoniazid; Male; Middle Aged; Prospective Studies; Pyrazinamide; Recurrence; Rifampin; Tuberculosis, Pulmonary | 1995 |
Randomised trial of thiacetazone and rifampicin-containing regimens for pulmonary tuberculosis in HIV-infected Ugandans. The Makerere University-Case Western University Research Collaboration.
Topics: Adolescent; Adult; AIDS-Related Opportunistic Infections; Drug Eruptions; Drug Hypersensitivity; Drug Therapy, Combination; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Streptomycin; Survival Rate; Thioacetazone; Tuberculosis, Pulmonary; Uganda | 1994 |
A comparison of two short course tuberculosis chemotherapy regimens, both using Rifater during an intensive phase, with a 3 year follow-up.
Topics: Adolescent; Adult; Antitubercular Agents; Drug Combinations; Female; Follow-Up Studies; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Retrospective Studies; Rifampin; Thailand; Treatment Outcome; Tuberculosis, Pulmonary | 1995 |
A controlled clinical trial of short-course chemotherapy for tuberculoma of the brain.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Antitubercular Agents; Child; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Tomography, X-Ray Computed; Tuberculoma, Intracranial | 1995 |
[Treatment of pleural tuberculosis with a short 4-month regimen: preliminary results].
Topics: Adult; Antitubercular Agents; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Isoniazid; Male; Prospective Studies; Pyrazinamide; Rifampin; Tuberculosis, Pleural | 1995 |
[Analysis of course and treatment results after treatment of pulmonary tuberculosis with early introduction of interrupted observation--preliminary report].
Topics: Adult; Aged; Aged, 80 and over; Antitubercular Agents; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Pulmonary; Uric Acid | 1995 |
Antituberculosis treatment-induced hepatotoxicity: role of predictive factors.
Topics: Adolescent; Adult; Antitubercular Agents; Body Mass Index; Case-Control Studies; Chemical and Drug Induced Liver Injury; Female; Humans; Isoniazid; Male; Middle Aged; Nutrition Disorders; Pyrazinamide; Rifampin | 1995 |
[Contemporary methods in the diagnosis and treatment of intrathoracic tuberculosis in children].
Topics: Administration, Oral; Child; Child, Preschool; Drug Therapy, Combination; Ethambutol; Follow-Up Studies; Humans; Injections, Intramuscular; Isoniazid; Pyrazinamide; Rifampin; Time Factors; Treatment Outcome; Tuberculosis, Pulmonary | 1994 |
Evaluation of the 3-drug combination, Rifater, versus 4-drug therapy in the ambulatory treatment of tuberculosis in Cape Town.
Topics: Antitubercular Agents; Drug Combinations; Drug Resistance, Microbial; Ethambutol; Humans; Isoniazid; Patient Compliance; Prospective Studies; Pyrazinamide; Rifampin; Sputum; Streptomycin; Tuberculosis | 1994 |
Study of the effect of concomitant food on the bioavailability of rifampicin, isoniazid and pyrazinamide.
Topics: Adolescent; Adult; Biological Availability; Cross-Over Studies; Dietary Carbohydrates; Dietary Fats; Female; Food; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 1995 |
[Compliance and tolerance of new antitubercular short-term chemopreventive regimens in childhood--a pilot project].
Topics: Adolescent; Antitubercular Agents; Child; Child, Preschool; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Infant; Isoniazid; Male; Pilot Projects; Pyrazinamide; Rifampin; Tuberculin Test; Tuberculosis, Pulmonary | 1994 |
[Six-month short course chemotherapy containing pyrazinamide for initial treatment of pulmonary tuberculosis].
Topics: Adolescent; Adult; Aged; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Pulmonary | 1994 |
A prospective evaluation of antituberculosis therapy in patients with human immunodeficiency virus infection.
Topics: Adult; AIDS-Related Opportunistic Infections; Antitubercular Agents; Drug Therapy, Combination; Ethambutol; Female; HIV-1; Humans; Isoniazid; Los Angeles; Male; Mycobacterium tuberculosis; Patient Compliance; Prospective Studies; Pyrazinamide; Remission Induction; Rifampin; Time Factors; Treatment Outcome; Tuberculosis, Pulmonary | 1994 |
Early bactericidal and sterilizing activities of ciprofloxacin in pulmonary tuberculosis.
Topics: Adult; Aged; Ciprofloxacin; Drug Therapy, Combination; Ethambutol; Female; HIV Seropositivity; HIV-1; Humans; Isoniazid; Male; Middle Aged; Mycobacterium tuberculosis; Prospective Studies; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 1993 |
Six months versus nine months chemotherapy for tuberculosis of lymph nodes: final results.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antitubercular Agents; Drug Administration Schedule; Drug Therapy, Combination; Ethambutol; Follow-Up Studies; Humans; Isoniazid; Middle Aged; Pyrazinamide; Rifampin; Tuberculosis, Lymph Node | 1993 |
[Combined chemotherapy of patients with tuberculosis - new regimens and dosage forms].
Topics: Antitubercular Agents; Dosage Forms; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Streptomycin; Time Factors; Tuberculosis, Pulmonary | 1993 |
[Results of short-term tuberculosis therapy with isoniazid, rifampicin and pyrazinamide].
Topics: Adult; Antitubercular Agents; Drug Combinations; Drug Resistance, Microbial; Female; Humans; Isoniazid; Male; Middle Aged; Patient Compliance; Pyrazinamide; Rifampin; Time Factors; Tuberculosis | 1993 |
Bioavailability of isoniazid, rifampicin and pyrazinamide (in free combination or fixed-triple formulation) in intermittent antituberculous chemotherapy.
Topics: Adult; Biological Availability; Capsules; Drug Administration Schedule; Drug Combinations; Half-Life; Humans; Isoniazid; Male; Pyrazinamide; Rifampin; Tablets; Tuberculosis, Pulmonary | 1993 |
Two-year follow-up of persons with HIV-1- and HIV-2-associated pulmonary tuberculosis treated with short-course chemotherapy in West Africa.
Topics: Adolescent; Adult; Africa, Western; AIDS-Related Opportunistic Infections; Antibiotics, Antitubercular; Antitubercular Agents; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Seronegativity; HIV Seropositivity; HIV-1; HIV-2; Humans; Isoniazid; Male; Pyrazinamide; Recurrence; Rifampin; Treatment Failure; Tuberculosis, Pulmonary | 1995 |
Randomized controlled trial of a drug regimen that includes ciprofloxacin for the treatment of pulmonary tuberculosis.
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Antitubercular Agents; Ciprofloxacin; Ethambutol; Female; HIV-1; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Time Factors; Tuberculosis, Pulmonary | 1996 |
Short course chemoprophylaxis with rifampicin, isoniazid and pyrazinamide for tuberculosis evaluated in gold miners with chronic silicosis: a double-blind placebo controlled trial.
Topics: Adult; Antitubercular Agents; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Follow-Up Studies; Gold; Humans; Isoniazid; Male; Middle Aged; Mining; Pyrazinamide; Rifampin; Silicotuberculosis | 1996 |
Pharmacokinetics of isoniazid in pulmonary tuberculosis--a comparative study at two dose levels.
Topics: Antibiotics, Antitubercular; Antitubercular Agents; Child; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Isoniazid; Male; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Pulmonary | 1996 |
A controlled trial of a 4-weekly supplement of rifampicin, pyrazinamide and streptomycin in the continuation phase of a 7-month daily chemotherapy regimen for pulmonary tuberculosis. Tanzania/British Medical Research Council Collaborative Investigation.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Black People; Body Weight; Drug Administration Schedule; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Humans; Isoniazid; Isonicotinic Acids; Male; Middle Aged; Mycobacterium tuberculosis; Pyrazinamide; Recurrence; Rifampin; Sputum; Streptomycin; Tuberculosis, Pulmonary | 1996 |
Treatment of multidrug-resistant tuberculosis in Indonesia.
Topics: Adult; Drug Resistance, Multiple; Drug Therapy, Combination; Female; Humans; Indonesia; Isoniazid; Male; Microbial Sensitivity Tests; Middle Aged; Mycobacterium tuberculosis; Nausea; Ofloxacin; Prospective Studies; Pyrazinamide; Rifampin; Tuberculosis, Multidrug-Resistant | 1996 |
[Compliance, efficacy and tolerability of the therapeutic regimen recommended by National Consensus on Tuberculosis].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antitubercular Agents; Child; Child, Preschool; Drug Therapy, Combination; Female; HIV Infections; Humans; Infant; Isoniazid; Male; Middle Aged; Patient Compliance; Prospective Studies; Pyrazinamide; Recurrence; Rifampin; Tuberculosis; Tuberculosis, Multidrug-Resistant | 1997 |
Pharmacokinetics of antimycobacterial drugs in patients with tuberculosis, AIDS, and diarrhea.
Topics: Adult; AIDS-Related Opportunistic Infections; Antitubercular Agents; Biological Availability; Diarrhea; Female; Humans; Isoniazid; Male; Prospective Studies; Pyrazinamide; Rifampin; Tuberculosis | 1997 |
A trial of three regimens to prevent tuberculosis in Ugandan adults infected with the human immunodeficiency virus. Uganda-Case Western Reserve University Research Collaboration.
Topics: Adult; AIDS-Related Opportunistic Infections; Antitubercular Agents; Drug Therapy, Combination; Female; HIV Infections; Humans; Isoniazid; Male; Pyrazinamide; Rifampin; Risk; Treatment Outcome; Tuberculin Test; Tuberculosis, Pulmonary | 1997 |
Susceptibility to levofloxacin of Myocobacterium tuberculosis isolates from patients with HIV-related tuberculosis and characterization of a strain with levofloxacin monoresistance. Community Programs for Clinical Research on AIDS 019 and the AIDS Clinica
Topics: AIDS-Related Opportunistic Infections; Anti-Infective Agents; Antibiotics, Antitubercular; Antitubercular Agents; Drug Resistance, Microbial; Drug Therapy, Combination; Ethambutol; Humans; In Vitro Techniques; Isoniazid; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Rifampin; Sputum; Tuberculosis | 1997 |
Population pharmacokinetic modeling of isoniazid, rifampin, and pyrazinamide.
Topics: Absorption; Adult; Analysis of Variance; Antibiotics, Antitubercular; Antitubercular Agents; Chromatography, High Pressure Liquid; Cross-Over Studies; Dose-Response Relationship, Drug; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin | 1997 |
Randomised controlled clinical trial of short course chemotherapy in abdominal tuberculosis: a five-year report.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Child; Drug Administration Schedule; Drug Therapy, Combination; Ethambutol; Female; Follow-Up Studies; Humans; Isoniazid; Male; Middle Aged; Prognosis; Pyrazinamide; Rifampin; Streptomycin; Time Factors; Tuberculosis, Gastrointestinal | 1997 |
A controlled clinical trial of oral short-course regimens in the treatment of sputum-positive pulmonary tuberculosis. Tuberculosis Research Centre.
Topics: Administration, Oral; Adolescent; Adult; Aged; Antitubercular Agents; Child; Drug Administration Schedule; Drug Resistance, Microbial; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Recurrence; Rifampin; Sputum; Tuberculosis, Pulmonary | 1997 |
Randomised trial of isoniazid versus rifampicin and pyrazinamide for prevention of tuberculosis in HIV-1 infection.
Topics: Adult; AIDS-Related Opportunistic Infections; Antitubercular Agents; Drug Administration Schedule; Female; Follow-Up Studies; HIV Infections; HIV-1; Humans; Isoniazid; Male; Prospective Studies; Pyrazinamide; Rifampin; Time Factors; Tuberculosis, Pulmonary | 1998 |
Prospective study of corticosteroid as an adjunct in the treatment of endobronchial tuberculosis in adults.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Bronchoscopy; Chi-Square Distribution; Drug Therapy, Combination; Ethambutol; Female; Follow-Up Studies; Glucocorticoids; Humans; Isoniazid; Lung; Male; Middle Aged; Prednisolone; Prospective Studies; Pyrazinamide; Radiography; Respiratory Function Tests; Rifampin; Streptomycin; Treatment Outcome; Tuberculosis, Pulmonary | 1997 |
Evaluation of an intensive intermittent-induction regimen and duration of short-course treatment for human immunodeficiency virus-related pulmonary tuberculosis. Terry Beirn Community Programs for Clinical Research on AIDS (CPCRA) and the AIDS Clinical Tr
Topics: Adult; AIDS-Related Opportunistic Infections; Antitubercular Agents; Drug Administration Schedule; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Levofloxacin; Male; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Recurrence; Rifampin; Sputum; Treatment Outcome; Tuberculosis, Pulmonary | 1998 |
Rifapentine and isoniazid in the continuation phase of treating pulmonary tuberculosis. Initial report.
Topics: Adolescent; Adult; Antitubercular Agents; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Streptomycin; Treatment Outcome; Tuberculosis, Pulmonary | 1998 |
Bioavailability of rifampicin, isoniazid and pyrazinamide from fixed-dose combination capsules.
Topics: Administration, Oral; Adult; Antibiotics, Antitubercular; Biological Availability; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Reference Values; Rifampin | 1998 |
[Lomefloxacin in complex treatment of acute progressive form of pulmonary tuberculosis].
Topics: Acute Disease; Adolescent; Adult; Animals; Anti-Infective Agents; Antibiotics, Antitubercular; Antitubercular Agents; Colony Count, Microbial; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; Ethambutol; Fluoroquinolones; Humans; Isoniazid; Mice; Middle Aged; Pyrazinamide; Quinolones; Streptomycin; Treatment Outcome; Tuberculosis, Pulmonary | 1998 |
Twice weekly tuberculosis preventive therapy in HIV infection in Zambia.
Topics: Adult; AIDS-Related Opportunistic Infections; Antibiotic Prophylaxis; Antibiotics, Antitubercular; Antitubercular Agents; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Incidence; Isoniazid; Male; Patient Compliance; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculin Test; Tuberculosis, Pulmonary; Zambia | 1998 |
Hepatic enzyme abnormalities in children on triple therapy for tuberculosis.
Topics: Adolescent; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Infant; Infant, Newborn; Isoniazid; Liver; Liver Function Tests; Male; Monitoring, Physiologic; Prognosis; Pyrazinamide; Rifampin; Tuberculosis | 1999 |
[Long-term efficacy of full course intermittent short-course chemotherapy on new smear positive tuberculosis patients].
Topics: Antitubercular Agents; Drug Therapy, Combination; Ethambutol; Follow-Up Studies; Humans; Isoniazid; Pyrazinamide; Recurrence; Rifampin; Streptomycin; Tuberculosis, Pulmonary | 1997 |
Assessment of a combined preparation of isoniazid, rifampicin and pyrazinamide (Rifater) in the initial phase of chemotherapy in three 6-month regimens for smear-positive pulmonary tuberculosis: a five-year follow-up report.
Topics: Antitubercular Agents; Drug Administration Schedule; Drug Combinations; Follow-Up Studies; Humans; Isoniazid; Pyrazinamide; Recurrence; Rifampin; Streptomycin; Tuberculosis, Pulmonary | 1999 |
Rifampin and pyrazinamide vs isoniazid for prevention of tuberculosis in HIV-infected persons: an international randomized trial. Terry Beirn Community Programs for Clinical Research on AIDS, the Adult AIDS Clinical Trials Group, the Pan American Health O
Topics: Adolescent; Adult; Aged; AIDS-Related Opportunistic Infections; Antitubercular Agents; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV Infections; Humans; Isoniazid; Male; Middle Aged; Patient Compliance; Proportional Hazards Models; Pyrazinamide; Rifampin; Statistics, Nonparametric; Tuberculin Test; Tuberculosis | 2000 |
Twice weekly vs. daily chemotherapy for childhood tuberculosis.
Topics: Antitubercular Agents; Child, Preschool; Drug Administration Schedule; Female; Humans; Infant; Isoniazid; Male; Patient Compliance; Pyrazinamide; Rifampin; South Africa; Treatment Outcome; Tuberculosis, Pulmonary | 2000 |
A randomised controlled trial of lay health workers as direct observers for treatment of tuberculosis.
Topics: Adult; Antitubercular Agents; Community Health Workers; Drug Combinations; Female; Humans; Isoniazid; Male; Pyrazinamide; Rifampin; South Africa; Tuberculosis | 2000 |
Long-term effect of preventive therapy for tuberculosis in a cohort of HIV-infected Zambian adults.
Topics: Adult; AIDS-Related Opportunistic Infections; Antitubercular Agents; CD4 Lymphocyte Count; Cohort Studies; Disease Progression; Female; Follow-Up Studies; HIV Infections; Humans; Isoniazid; Male; Pyrazinamide; Rifampin; Time Factors; Treatment Outcome; Tuberculosis; Zambia | 2001 |
Modified short-course chemotherapy of pulmonary tuberculosis in Ibadan, Nigeria--a preliminary report.
Topics: Adolescent; Adult; Antitubercular Agents; Developing Countries; Drug Administration Schedule; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Male; Middle Aged; Nigeria; Pyrazinamide; Rifampin; Sputum; Streptomycin; Thioacetazone; Time Factors; Treatment Outcome; Tuberculosis, Pulmonary; Urban Health; World Health Organization | 2000 |
[Controlled clinical study on efficacy of fixed-dose compounds rifater/rifinah in antituberculous chemotherapy].
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Drug Therapy, Combination; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 1998 |
The potential use of urinary excretion data for assessing the relative bioavailability of rifampicin in fixed dose combination anti-tuberculosis formulations.
Topics: Antibiotics, Antitubercular; Area Under Curve; Biological Availability; Chromatography, High Pressure Liquid; Colorimetry; Cross-Over Studies; Drug Combinations; Ethambutol; Humans; Isoniazid; Male; Pyrazinamide; Quality Control; Reference Values; Rifampin; Therapeutic Equivalency; Tuberculosis; Urinalysis | 2001 |
Reintroducing antituberculosis therapy after Stevens-Johnson syndrome in human immunodeficiency virus-infected patients with tuberculosis: role of desensitization.
Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Antitubercular Agents; Desensitization, Immunologic; Dose-Response Relationship, Drug; Ethambutol; Female; Humans; Isoniazid; Male; Pyrazinamide; Rifampin; Stevens-Johnson Syndrome; Treatment Outcome; Tuberculosis | 2001 |
Duration of efficacy of treatment of latent tuberculosis infection in HIV-infected adults.
Topics: Adolescent; Adult; AIDS-Related Opportunistic Infections; Antitubercular Agents; Drug Therapy, Combination; Female; HIV Infections; Humans; Incidence; Isoniazid; Male; Microbial Sensitivity Tests; Middle Aged; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Time Factors; Treatment Outcome; Tuberculin Test; Tuberculosis, Pulmonary | 2001 |
Treatment of childhood tuberculosis with a six month directly observed regimen of only two weeks of daily therapy.
Topics: Adolescent; Antibiotics, Antitubercular; Antitubercular Agents; Child; Child, Preschool; Directly Observed Therapy; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Infant; Isoniazid; Male; Patient Compliance; Pyrazinamide; Recurrence; Rifampin; Treatment Outcome; Tuberculosis, Pulmonary | 2002 |
Rifapentine and isoniazid in the continuation phase of a 6-month regimen. Final report at 5 years: prognostic value of various measures.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibiotics, Antitubercular; Antitubercular Agents; Child; Drug Therapy, Combination; Female; Hong Kong; Humans; Isoniazid; Life Tables; Male; Middle Aged; Prognosis; Proportional Hazards Models; Pyrazinamide; Rifampin; Streptomycin; Treatment Outcome; Tuberculosis, Pulmonary | 2002 |
Side-effects of drugs used in directly observed treatment short-course in newly diagnosed pulmonary tuberculosis subjects in Nigerians: a controlled clinical study.
Topics: Adolescent; Adult; Antitubercular Agents; Clinical Protocols; Directly Observed Therapy; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Nigeria; Pyrazinamide; Rifampin; Time Factors; Tuberculosis, Pulmonary | 2002 |
Short-course rifampin and pyrazinamide compared with isoniazid for latent tuberculosis infection: a multicenter clinical trial.
Topics: Adult; Antibiotics, Antitubercular; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Isoniazid; Liver; Liver Function Tests; Male; Prospective Studies; Pyrazinamide; Rifampin | 2002 |
Bioequivalence assessment of rifampicin, isoniazid and pyrazinamide in a fixed dose combination of rifampicin, isoniazid, pyrazinamide and ethambutol vs. separate formulations.
Topics: Analysis of Variance; Antibiotics, Antitubercular; Cross-Over Studies; Drug Combinations; Ethambutol; Humans; Isoniazid; Male; Pyrazinamide; Rifampin; Therapeutic Equivalency; Time Factors; Tuberculosis | 2002 |
Fixed-dose combination chemotherapy (Rifater/Rifinah) for active pulmonary tuberculosis in Taiwan: a two-year follow-up.
Topics: Adult; Antitubercular Agents; Drug Combinations; Female; Humans; Isoniazid; Male; Mycobacterium tuberculosis; Patient Compliance; Pyrazinamide; Rifampin; Sputum; Taiwan; Tuberculosis, Pulmonary | 2002 |
Results of a 12-month regimen for drug-resistant pulmonary tuberculosis.
Topics: Adolescent; Adult; Antibiotics, Antitubercular; Antitubercular Agents; Drug Administration Schedule; Ethambutol; Female; Follow-Up Studies; Humans; Isoniazid; Male; Middle Aged; Outcome Assessment, Health Care; Prospective Studies; Pyrazinamide; Rifampin; Streptomycin; Time Factors; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 2002 |
Comparative evaluation of efficacy and safety profile of three anti-tuberculous regimens in Mangalore.
Topics: Adult; Antitubercular Agents; Dizziness; Drug Therapy, Combination; Ethambutol; Female; Follow-Up Studies; Gastritis; Humans; Hypesthesia; Isoniazid; Male; Nausea; Pyrazinamide; Rifampin; Streptomycin; Treatment Outcome; Tuberculosis, Pulmonary | 2002 |
The clearance of theophylline is increased during the initial period of tuberculosis treatment.
Topics: Adult; Aged; Antitubercular Agents; Bronchodilator Agents; Drug Interactions; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Prospective Studies; Pyrazinamide; Rifampin; Theophylline; Time Factors; Tuberculosis, Pulmonary | 2003 |
Evaluation of bioequivalence of isoniazid and pyrazinamide in three and four drugs fixed dose combinations using WHO simplified protocol.
Topics: Administration, Oral; Adult; Analysis of Variance; Antitubercular Agents; Area Under Curve; Chemistry, Pharmaceutical; Clinical Protocols; Cross-Over Studies; Dosage Forms; Drug Administration Schedule; Drug Combinations; Drug Evaluation; Ethambutol; Half-Life; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Therapeutic Equivalency; World Health Organization | 2003 |
Use of Rhu-GM-CSF in pulmonary tuberculosis patients: results of a randomized clinical trial.
Topics: Adjuvants, Immunologic; Adolescent; Adult; Antitubercular Agents; Double-Blind Method; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Pulmonary | 2003 |
Initial experience on rifampin and pyrazinamide vs isoniazid in the treatment of latent tuberculosis infection among patients with silicosis in Hong Kong.
Topics: Aged; Antitubercular Agents; Drug Administration Schedule; Female; Hong Kong; Humans; Isoniazid; Male; Middle Aged; Patient Compliance; Pyrazinamide; Rifampin; Risk Factors; Silicosis; Tuberculosis | 2003 |
[Assessment of the use of a multicomponent drug in the treatment of new cases of pulmonary tuberculosis].
Topics: Adolescent; Adult; Drug Combinations; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Mycobacterium tuberculosis; Pyrazinamide; Radiography; Rifampin; Sputum; Time Factors; Tuberculosis, Pulmonary | 2003 |
Short-course rifampin and pyrazinamide compared with isoniazid for latent tuberculosis infection: a cost-effectiveness analysis based on a multicenter clinical trial.
Topics: Adolescent; Adult; Antitubercular Agents; Cost Savings; Cost-Benefit Analysis; Costs and Cost Analysis; Humans; Isoniazid; Pyrazinamide; Rifampin; Tuberculosis | 2004 |
[Treatment of latent tuberculosis among homeless population. Comparison between wo therapeutic approaches].
Topics: Adult; Antitubercular Agents; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Ill-Housed Persons; Isoniazid; Male; Patient Compliance; Prospective Studies; Pyrazinamide; Rifampin; Tuberculosis | 2004 |
Comparative bioavailability of rifampicin, isoniazid and pyrazinamide from a four drug fixed dose combination with separate formulations at the same dose levels.
Topics: Administration, Oral; Adult; Antitubercular Agents; Area Under Curve; Biological Availability; Chemistry, Pharmaceutical; Drug Combinations; Half-Life; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Therapeutic Equivalency | 2004 |
Split-drug regimens for the treatment of patients with sputum smear-positive pulmonary tuberculosis--a unique approach.
Topics: Adult; Antitubercular Agents; Drug Resistance, Bacterial; Drug Therapy, Combination; Ethambutol; Female; Follow-Up Studies; Humans; Isoniazid; Male; Pyrazinamide; Rifampin; Risk Factors; Survival Analysis; Treatment Outcome; Tuberculosis, Pulmonary | 2004 |
The short-term effects of anti-tuberculosis therapy on plasma pyridoxine levels in patients with pulmonary tuberculosis.
Topics: Adult; Antitubercular Agents; Ethambutol; Female; Follow-Up Studies; HIV Infections; Humans; Isoniazid; Male; Pyrazinamide; Pyridoxine; Rifampin; Time Factors; Tuberculosis, Pulmonary | 2004 |
Disposition of uric acid upon administration of ofloxacin alone and in combination with other anti-tuberculosis drugs.
Topics: Adult; Antitubercular Agents; Clinical Trials as Topic; Humans; Isoniazid; Male; Ofloxacin; Pyrazinamide; Rifampin; Uric Acid | 2004 |
Decreased bioavailability of rifampin and other antituberculosis drugs in patients with advanced human immunodeficiency virus disease.
Topics: Acetylation; Adult; Antibiotics, Antitubercular; Antitubercular Agents; Biological Availability; Ethambutol; Feces; Female; HIV Infections; Humans; Intestinal Absorption; Isoniazid; Male; Middle Aged; Phenotype; Pyrazinamide; Rifampin; Tuberculosis | 2004 |
Penetration of isoniazid, rifampicin and pyrazinamide in tuberculous pleural effusion and psoas abscess.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Female; Humans; Isoniazid; Male; Microbial Sensitivity Tests; Middle Aged; Netherlands; Pleural Effusion; Psoas Abscess; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary; Young Adult | 2004 |
[Optimization of tuberculosis complex chemotherapy with the use of moxifloxacin].
Topics: Adolescent; Adult; Animals; Antitubercular Agents; Aza Compounds; Drug Therapy, Combination; Female; Fluoroquinolones; Humans; Isoniazid; Male; Mice; Middle Aged; Moxifloxacin; Pyrazinamide; Quinolines; Tuberculosis, Pulmonary | 2004 |
Evaluation of modified short course chemotherapy in active pulmonary tuberculosis patients with human immunodeficiency virus infection in University College Hospital, Ibadan, Nigeria--a preliminary report.
Topics: Acne Vulgaris; Adolescent; Adult; Age Distribution; Aged; Antitubercular Agents; Drug Therapy, Combination; Ethambutol; Female; HIV Infections; Humans; Isoniazid; Male; Middle Aged; Nigeria; Pyrazinamide; Radiography; Rifampin; Tuberculosis, Pulmonary | 2004 |
Short-course chemotherapy for paediatric respiratory tuberculosis: 5-year report.
Topics: Antitubercular Agents; Child; Child, Preschool; Drug Administration Schedule; Drug Therapy, Combination; Follow-Up Studies; Humans; Infant; Isoniazid; Pyrazinamide; Rifampin; Statistics, Nonparametric; Tuberculosis, Pulmonary | 2005 |
[Randomized control study on domestic fixed-dose combinations in the initial treatment of smears positive tuberculosis].
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Clinical Protocols; Drug Therapy, Combination; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Pulmonary; Young Adult | 2004 |
Treatment of lymph node tuberculosis--a randomized clinical trial of two 6-month regimens.
Topics: Adolescent; Adult; Antibiotics, Antitubercular; Antitubercular Agents; Child; Directly Observed Therapy; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Isoniazid; Lymph Nodes; Male; Middle Aged; Mycobacterium tuberculosis; Pyrazinamide; Recurrence; Rifampin; Self Administration; Treatment Outcome; Tuberculin Test; Tuberculosis, Lymph Node | 2005 |
Weekly rifapentine/isoniazid or daily rifampin/pyrazinamide for latent tuberculosis in household contacts.
Topics: Adult; Antitubercular Agents; Disease Progression; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Incidence; Isoniazid; Male; Pyrazinamide; Retrospective Studies; Rifampin; Treatment Outcome; Tuberculosis, Pulmonary | 2006 |
Pharmacokinetics and tolerability of a higher rifampin dose versus the standard dose in pulmonary tuberculosis patients.
Topics: Adolescent; Adult; Antibiotics, Antitubercular; Antitubercular Agents; Area Under Curve; Biological Availability; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Drug Tolerance; Ethambutol; Female; Half-Life; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Radiography, Thoracic; Rifampin; Treatment Outcome; Tuberculosis, Pulmonary | 2007 |
[Randomized clinical trial investigating three chemoprophylaxis regimens for latent tuberculosis infection in HIV-infected patients].
Topics: Adult; Antitubercular Agents; Drug Therapy, Combination; Female; HIV Infections; Humans; Isoniazid; Male; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Tuberculosis; Virus Latency | 2007 |
Evaluation of a non-rifampicin continuation phase (6HE) following thrice-weekly intensive phase for the treatment of new sputum positive pulmonary tuberculosis.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Drug Administration Schedule; Drug Resistance, Bacterial; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Sputum; Treatment Outcome; Tuberculosis, Pulmonary | 2007 |
Low serum concentrations of anti-tuberculosis drugs and determinants of their serum levels.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antitubercular Agents; Chromatography, Liquid; Drug Monitoring; Ethambutol; Female; Humans; Isoniazid; Linear Models; Male; Mass Spectrometry; Middle Aged; Pyrazinamide; Rifampin; Tuberculosis | 2007 |
A Phase II study of the sterilising activities of ofloxacin, gatifloxacin and moxifloxacin in pulmonary tuberculosis.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Antitubercular Agents; Aza Compounds; Colony Count, Microbial; Drug Therapy, Combination; Female; Fluoroquinolones; Gatifloxacin; Humans; Isoniazid; Male; Middle Aged; Moxifloxacin; Nonlinear Dynamics; Ofloxacin; Pyrazinamide; Quinolines; Rifampin; Sputum | 2008 |
Nutritional status of persons with HIV infection, persons with HIV infection and tuberculosis, and HIV-negative individuals from southern India.
Topics: Adult; AIDS-Related Opportunistic Infections; Anemia; Antitubercular Agents; Body Composition; Drug Therapy, Combination; Ethambutol; HIV Infections; HIV Seronegativity; Humans; Hypoalbuminemia; India; Isoniazid; Malnutrition; Nutritional Status; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Pulmonary | 2008 |
Clinical evaluation and monitoring of adverse effects for fixed multidose combination against single drug therapy in pulmonary tuberculosis patients.
Topics: Adolescent; Adult; Antitubercular Agents; Dose-Response Relationship, Drug; Drug Monitoring; Drug Therapy, Combination; Educational Status; Employment; Ethambutol; Humans; Isoniazid; Middle Aged; Pakistan; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 2008 |
[Relapse rate of pulmonary tuberculosis within two years following completion of twice weekly intermittent chemotherapy].
Topics: Adult; Aged; Aged, 80 and over; Antitubercular Agents; Directly Observed Therapy; Drug Administration Schedule; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Recurrence; Rifampin; Self Administration; Tuberculosis, Pulmonary | 2008 |
Pyrazinamide serum levels in childhood tuberculosis.
Topics: Adolescent; Antitubercular Agents; Child; Child, Preschool; Drug Therapy, Combination; Humans; Infant; Isoniazid; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 2008 |
Prevention of hepatotoxicity due to anti tuberculosis treatment: a novel integrative approach.
Topics: Adult; Antitubercular Agents; Blood Sedimentation; Body Weight; Chemical and Drug Induced Liver Injury; Curcuma; Drug Therapy, Combination; Ethambutol; Female; Hemoglobins; Humans; Isoniazid; Liver Diseases; Male; Middle Aged; Patient Compliance; Plant Preparations; Pyrazinamide; Rifampin; Tinospora; Treatment Outcome; Tuberculosis | 2008 |
Moxifloxacin versus ethambutol in the initial treatment of tuberculosis: a double-blind, randomised, controlled phase II trial.
Topics: Adult; Antitubercular Agents; Aza Compounds; Brazil; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Ethambutol; Female; Fluoroquinolones; Humans; Isoniazid; Kaplan-Meier Estimate; Logistic Models; Male; Moxifloxacin; Multivariate Analysis; Pyrazinamide; Quinolines; Rifampin; Sputum; Time Factors; Treatment Outcome; Tuberculosis, Pulmonary | 2009 |
Comparison of a four-drug fixed-dose combination regimen with a single tablet regimen in smear-positive pulmonary tuberculosis.
Topics: Adult; Antitubercular Agents; Drug Combinations; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Patient Satisfaction; Pyrazinamide; Rifampin; Sputum; Treatment Outcome; Tuberculosis, Pulmonary | 2009 |
Shortening treatment in adults with noncavitary tuberculosis and 2-month culture conversion.
Topics: Adult; Antitubercular Agents; Drug Administration Schedule; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Kaplan-Meier Estimate; Male; Mycobacterium tuberculosis; Proportional Hazards Models; Pyrazinamide; Rifampin; Sputum; Treatment Outcome; Tuberculosis, Pulmonary | 2009 |
Prospective randomized trial of six-month versus nine-month therapy for intestinal tuberculosis.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Gastrointestinal; Young Adult | 2009 |
Efficacy of a 6-month versus 9-month intermittent treatment regimen in HIV-infected patients with tuberculosis: a randomized clinical trial.
Topics: Adult; AIDS-Related Opportunistic Infections; Antitubercular Agents; CD4 Lymphocyte Count; Drug Administration Schedule; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Ethambutol; Female; HIV Infections; Humans; Isoniazid; Kaplan-Meier Estimate; Logistic Models; Male; Medication Adherence; Pyrazinamide; Rifampin; Tuberculosis; Viral Load | 2010 |
Patient-centred tuberculosis treatment delivery under programmatic conditions in Tanzania: a cohort study.
Topics: Adult; Antitubercular Agents; Cohort Studies; Directly Observed Therapy; Ethambutol; Humans; Isoniazid; Middle Aged; Pyrazinamide; Rifampin; Tanzania; Treatment Outcome; Tuberculosis; Young Adult | 2009 |
Safety of 3 different reintroduction regimens of antituberculosis drugs after development of antituberculosis treatment-induced hepatotoxicity.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Female; Humans; Isoniazid; Male; Middle Aged; Prospective Studies; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis; Young Adult | 2010 |
Tuberculosis treatment in HIV infected Ugandans with CD4 counts>350 cells/mm reduces immune activation with no effect on HIV load or CD4 count.
Topics: Adult; Antitubercular Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cohort Studies; Ethambutol; Female; Flow Cytometry; HIV Infections; HIV-1; Humans; Isoniazid; Male; Middle Aged; Prospective Studies; Pyrazinamide; Rifampin; Tuberculosis; Uganda; Viral Load; Young Adult | 2010 |
Protective effect of N-acetylcysteine on antituberculosis drug-induced hepatotoxicity.
Topics: Acetylcysteine; Aged; Aged, 80 and over; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Drug Interactions; Drug Therapy, Combination; Ethambutol; Female; Free Radical Scavengers; Humans; Isoniazid; Liver; Male; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 2010 |
Relative bioavailability of rifampicin in a three-drug fixed-dose combination formulation.
Topics: Adult; Antitubercular Agents; Area Under Curve; Biological Availability; Cross-Over Studies; Double-Blind Method; Drug Combinations; Drugs, Generic; Humans; Isoniazid; Mexico; Pyrazinamide; Rifampin; Therapeutic Equivalency; Young Adult | 2010 |
Genital tuberculosis among infertile women and fertility outcome after antitubercular therapy.
Topics: Adult; Antitubercular Agents; Drug Therapy, Combination; Ethambutol; Female; Fertilization; Humans; Infertility, Female; Isoniazid; Laparoscopy; Polymerase Chain Reaction; Pregnancy; Prospective Studies; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Female Genital | 2011 |
Efficacy and safety of a 4-drug fixed-dose combination regimen compared with separate drugs for treatment of pulmonary tuberculosis: the Study C randomized controlled trial.
Topics: Adult; Antitubercular Agents; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Pulmonary; Young Adult | 2011 |
Randomized pharmacokinetic and pharmacodynamic comparison of fluoroquinolones for tuberculous meningitis.
Topics: Administration, Oral; Adolescent; Adult; Aged; Ciprofloxacin; Ethambutol; Female; Fluoroquinolones; Gatifloxacin; Humans; Injections, Intramuscular; Isoniazid; Levofloxacin; Male; Middle Aged; Multivariate Analysis; Ofloxacin; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Meningeal; Young Adult | 2011 |
Results at 30 months of a randomised trial of two 8-month regimens for the treatment of tuberculosis.
Topics: Adolescent; Adult; Aged; Antibiotics, Antitubercular; Antitubercular Agents; Drug Combinations; Drug Therapy, Combination; Ethambutol; Female; Humans; Intention to Treat Analysis; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Sputum; Treatment Failure; Tuberculosis, Pulmonary; World Health Organization; Young Adult | 2011 |
Pharmacokinetics of isoniazid, rifampin, and pyrazinamide in children younger than two years of age with tuberculosis: evidence for implementation of revised World Health Organization recommendations.
Topics: Antitubercular Agents; Area Under Curve; Child, Preschool; Coinfection; Female; HIV Infections; Humans; Isoniazid; Male; Nutritional Status; Practice Guidelines as Topic; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis; Tuberculosis, Pulmonary; World Health Organization | 2011 |
Phase II dose-ranging trial of the early bactericidal activity of PA-824.
Topics: Adolescent; Adult; Antitubercular Agents; Drug Administration Schedule; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Nitroimidazoles; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary; Young Adult | 2012 |
Efavirenz, tenofovir and emtricitabine combined with first-line tuberculosis treatment in tuberculosis-HIV-coinfected Tanzanian patients: a pharmacokinetic and safety study.
Topics: Adenine; Adult; Alkynes; Anti-HIV Agents; Antitubercular Agents; Benzoxazines; Cyclopropanes; Deoxycytidine; Drug Combinations; Drug Therapy, Combination; Efavirenz, Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; Ethambutol; Female; HIV Infections; Humans; Isoniazid; Male; Organophosphonates; Oxazines; Pyrazinamide; Reverse Transcriptase Inhibitors; Rifampin; Treatment Outcome; Tuberculosis, Pulmonary | 2013 |
A time-to-event pharmacodynamic model describing treatment response in patients with pulmonary tuberculosis using days to positivity in automated liquid mycobacterial culture.
Topics: Antimalarials; Bacterial Load; Bacteriological Techniques; Diagnostic Techniques, Respiratory System; Ethambutol; Humans; Isoniazid; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Sputum; Treatment Outcome; Tuberculosis, Pulmonary | 2013 |
Tuberculous lymphadenopathy: a multicentre operational study of 6-month thrice weekly directly observed treatment.
Topics: Adolescent; Adult; Antitubercular Agents; Child; Child, Preschool; Directly Observed Therapy; Drug Administration Schedule; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Lymph Node; Young Adult | 2013 |
Oral bioavailability of rifampicin, isoniazid, ethambutol, and pyrazinamide in a 4-drug fixed-dose combination compared with the separate formulations in healthy Chinese male volunteers.
Topics: Adult; Antitubercular Agents; Area Under Curve; China; Chromatography, High Pressure Liquid; Cross-Over Studies; Drug Combinations; Ethambutol; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Tandem Mass Spectrometry; Therapeutic Equivalency | 2013 |
Evaluation of initial and steady-state gatifloxacin pharmacokinetics and dose in pulmonary tuberculosis patients by using monte carlo simulations.
Topics: Adult; Antitubercular Agents; Area Under Curve; Coinfection; Drug Administration Schedule; Drug Dosage Calculations; Drug Synergism; Drug Therapy, Combination; Female; Fluoroquinolones; Gatifloxacin; HIV Infections; Humans; Isoniazid; Male; Monte Carlo Method; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 2013 |
Impact of tuberculosis treatment on CD4 cell count, HIV RNA, and p24 antigen in patients with HIV and tuberculosis.
Topics: Adult; Antitubercular Agents; Biomarkers; CD4 Lymphocyte Count; Coinfection; Dietary Supplements; Drug Therapy, Combination; Ethambutol; Female; Guinea-Bissau; HIV Core Protein p24; HIV Infections; HIV-1; HIV-2; Humans; Isoniazid; Kaplan-Meier Estimate; Male; Middle Aged; Pyrazinamide; Rifampin; RNA, Viral; Tuberculosis, Pulmonary; Vitamin D; Young Adult | 2013 |
Bioequivalence of fixed-dose combination Myrin®-P Forte and reference drugs in loose combination.
Topics: Adult; Antitubercular Agents; Area Under Curve; Cross-Over Studies; Drug Combinations; Drug Therapy, Combination; Ethambutol; Fasting; Female; Healthy Volunteers; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Singapore; Therapeutic Equivalency; Young Adult | 2013 |
Relative bioavailability of isoniazid in a fixed-dose combination product in healthy Mexican subjects.
Topics: Administration, Oral; Adult; Antitubercular Agents; Area Under Curve; Biological Availability; Cross-Over Studies; Drug Combinations; Drugs, Generic; Female; Half-Life; Healthy Volunteers; Humans; Isoniazid; Male; Metabolic Clearance Rate; Pyrazinamide; Rifampin; Therapeutic Equivalency; Young Adult | 2014 |
The pharmacokinetics of a single oral or rectal dose of concurrently administered isoniazid, rifampin, pyrazinamide, and ethambutol in Asian elephants (Elephas maximus).
Topics: Administration, Oral; Administration, Rectal; Animals; Antitubercular Agents; Area Under Curve; Cross-Over Studies; Drug Combinations; Elephants; Ethambutol; Female; Isoniazid; Male; Pyrazinamide; Rifampin | 2014 |
Safety and efficacy of levofloxacin versus rifampicin in tuberculous meningitis: an open-label randomized controlled trial.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Aspirin; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Levofloxacin; Male; Middle Aged; Prednisolone; Pyrazinamide; Radiography; Rifampin; Treatment Outcome; Tuberculosis, Meningeal; Young Adult | 2014 |
Intermittent tuberculosis treatment for patients with isoniazid intolerance or drug resistance.
Topics: Adult; Ambulatory Care Facilities; Antitubercular Agents; Canada; Directly Observed Therapy; Drug Administration Schedule; Drug Resistance, Bacterial; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Prospective Studies; Pyrazinamide; Rifampin; Time Factors; Treatment Outcome; Tuberculosis; United States | 2014 |
Four-month moxifloxacin-based regimens for drug-sensitive tuberculosis.
Topics: Adult; Antitubercular Agents; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Ethambutol; Female; Fluoroquinolones; HIV Seropositivity; Humans; Isoniazid; Kaplan-Meier Estimate; Male; Moxifloxacin; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary; Young Adult | 2014 |
Evaluation of a standardized treatment regimen of anti-tuberculosis drugs for patients with multi-drug-resistant tuberculosis (STREAM): study protocol for a randomized controlled trial.
Topics: Antitubercular Agents; Bangladesh; Clinical Protocols; Clofazimine; Drug Administration Schedule; Drug Therapy, Combination; Ethambutol; Fluoroquinolones; Humans; Isoniazid; Kanamycin; Moxifloxacin; Prothionamide; Pyrazinamide; Research Design; Time Factors; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 2014 |
Results at 30 months of a randomised trial of FDCs and separate drugs for the treatment of tuberculosis.
Topics: Africa; Antitubercular Agents; Asia; Dose-Response Relationship, Drug; Drug Combinations; Ethambutol; Female; Follow-Up Studies; Humans; Isoniazid; Latin America; Male; Pyrazinamide; Recurrence; Rifampin; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 2014 |
Impact of nonlinear interactions of pharmacokinetics and MICs on sputum bacillary kill rates as a marker of sterilizing effect in tuberculosis.
Topics: Adolescent; Adult; Antitubercular Agents; Area Under Curve; Disinfection; Drug Antagonism; Drug Synergism; Drug Therapy, Combination; Ethambutol; Female; HIV Infections; Humans; Isoniazid; Male; Microbial Sensitivity Tests; Middle Aged; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Sputum; Sterilization; Treatment Outcome; Tuberculosis; Young Adult | 2015 |
Effect of micronutrient supplementation on treatment outcomes in children with intrathoracic tuberculosis: a randomized controlled trial.
Topics: Adolescent; Antitubercular Agents; Body Height; Body Mass Index; Body Weight; Child; Child, Preschool; Dietary Supplements; Double-Blind Method; Ethambutol; Female; Humans; India; Infant; Isoniazid; Male; Micronutrients; Patient Compliance; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis; Zinc | 2014 |
A four-month gatifloxacin-containing regimen for treating tuberculosis.
Topics: Adult; Antitubercular Agents; Blood Glucose; Drug Administration Schedule; Drug Therapy, Combination; Ethambutol; Female; Fluoroquinolones; Gatifloxacin; Humans; Intention to Treat Analysis; Isoniazid; Male; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 2014 |
High-dose rifapentine with moxifloxacin for pulmonary tuberculosis.
Topics: Adolescent; Adult; Antitubercular Agents; Coinfection; Drug Administration Schedule; Drug Therapy, Combination; Ethambutol; Female; Fluoroquinolones; HIV Seropositivity; Humans; Isoniazid; Kaplan-Meier Estimate; Male; Middle Aged; Moxifloxacin; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary; Young Adult | 2014 |
Pharmacokinetics of first-line antituberculosis drugs in HIV-infected children with tuberculosis treated with intermittent regimens in India.
Topics: Adolescent; Antitubercular Agents; Child; Child, Preschool; Female; HIV Infections; Humans; India; Infant; Isoniazid; Male; Pyrazinamide; Regression Analysis; Rifampin; Treatment Outcome; Tuberculosis | 2015 |
A dose-ranging trial to optimize the dose of rifampin in the treatment of tuberculosis.
Topics: Adolescent; Adult; Antibiotics, Antitubercular; Bacterial Load; Drug Dosage Calculations; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary; Young Adult | 2015 |
A randomized trial comparing standard outcomes in two treatment models for substance users with tuberculosis.
Topics: Adult; Antitubercular Agents; Directly Observed Therapy; Drug Users; Ethambutol; Ethnicity; Female; Humans; Isoniazid; Male; Patient Compliance; Pyrazinamide; Rifampin; Socioeconomic Factors; Substance-Related Disorders; Treatment Outcome; Tuberculosis | 2015 |
Efficiency and safety of the combination of moxifloxacin, pretomanid (PA-824), and pyrazinamide during the first 8 weeks of antituberculosis treatment: a phase 2b, open-label, partly randomised trial in patients with drug-susceptible or drug-resistant pul
Topics: Adolescent; Adult; Antitubercular Agents; Colony Count, Microbial; Drug Therapy, Combination; Ethambutol; Female; Fluoroquinolones; Humans; Isoniazid; Male; Moxifloxacin; Nitroimidazoles; Pyrazinamide; Rifampin; South Africa; Sputum; Tanzania; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Young Adult | 2015 |
Two-stage activity-safety study of daily rifapentine during intensive phase treatment of pulmonary tuberculosis.
Topics: Adult; Antitubercular Agents; Drug Administration Schedule; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; South Africa; Sputum; Treatment Outcome; Tuberculosis, Pulmonary; Young Adult | 2015 |
Effects on type 2 diabetes complicated with pulmonary tuberculosis: regiment of insulin, isoniazid, rifampicin, pyrazinamide and ethambutol versus the regiment plus Qi-boosting and Yin-nourishing decoction of Traditional Chinese Medicine.
Topics: Adult; Aged; Antitubercular Agents; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Drugs, Chinese Herbal; Ethambutol; Female; Humans; Hypoglycemic Agents; Insulin; Isoniazid; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 2015 |
Pharmacokinetics of Antituberculosis Drugs in HIV-Positive and HIV-Negative Adults in Malawi.
Topics: Adolescent; Adult; Antitubercular Agents; Ethambutol; Female; HIV Infections; Humans; Isoniazid; Malawi; Male; Middle Aged; Pyrazinamide; Rifampin; Young Adult | 2015 |
Effect of SLCO1B1 Polymorphisms on Rifabutin Pharmacokinetics in African HIV-Infected Patients with Tuberculosis.
Topics: Adult; Antitubercular Agents; Area Under Curve; CD4 Lymphocyte Count; Coinfection; Ethambutol; Female; Gene Expression; HIV Infections; Humans; Isoniazid; Liver-Specific Organic Anion Transporter 1; Male; Monte Carlo Method; Organic Anion Transporters; Polymorphism, Single Nucleotide; Pyrazinamide; Rifabutin; Rifampin; Sex Factors; Tuberculosis, Pulmonary | 2016 |
Pharmacokinetics of Isoniazid, Pyrazinamide, and Ethambutol in Newly Diagnosed Pulmonary TB Patients in Tanzania.
Topics: Adult; Antitubercular Agents; Ethambutol; Female; Humans; Isoniazid; Male; Pyrazinamide; Tanzania; Tuberculosis, Pulmonary | 2015 |
Pharmacokinetics of Rifampin, Isoniazid, Pyrazinamide, and Ethambutol in Infants Dosed According to Revised WHO-Recommended Treatment Guidelines.
Topics: Anti-Bacterial Agents; Area Under Curve; Coinfection; Drug Dosage Calculations; Ethambutol; Female; HIV; HIV Infections; Humans; Infant; Infant, Newborn; Isoniazid; Male; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Practice Guidelines as Topic; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 2016 |
Tackling the unknowns of short-course rifapentine-based treatment for active tuberculosis: a decision analysis.
Topics: Antitubercular Agents; Decision Support Techniques; Ethambutol; Humans; Isoniazid; Markov Chains; Pyrazinamide; Recurrence; Rifampin; Treatment Outcome; Tuberculosis | 2016 |
A randomised Phase II trial to evaluate the toxicity of high-dose rifampicin to treat pulmonary tuberculosis.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Dose-Response Relationship, Drug; Ethambutol; Female; Follow-Up Studies; Humans; Isoniazid; Male; Middle Aged; Patient Compliance; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Pulmonary; Young Adult | 2016 |
Safety and efficacy of additional levofloxacin in tuberculous meningitis: A randomized controlled pilot study.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Disability Evaluation; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Levofloxacin; Male; Middle Aged; Pilot Projects; Proportional Hazards Models; Pyrazinamide; Rifampin; Seizures; Time Factors; Treatment Outcome; Tuberculosis, Meningeal; Young Adult | 2016 |
A Phase 2 Randomized Trial of a Rifapentine plus Moxifloxacin-Based Regimen for Treatment of Pulmonary Tuberculosis.
Topics: Adult; Antitubercular Agents; Case-Control Studies; Drug Therapy, Combination; Female; Fluoroquinolones; Humans; Isoniazid; Male; Middle Aged; Moxifloxacin; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 2016 |
Efficacy and Safety of 'Fixed Dose' versus 'Loose' Drug Regimens for Treatment of Pulmonary Tuberculosis in Two High TB-Burden African Countries: A Randomized Controlled Trial.
Topics: Adult; Africa; Aged; Antitubercular Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Sputum; Treatment Outcome; Tuberculosis, Pulmonary | 2016 |
Delamanid Coadministered with Antiretroviral Drugs or Antituberculosis Drugs Shows No Clinically Relevant Drug-Drug Interactions in Healthy Subjects.
Topics: Adult; Alkynes; Anti-HIV Agents; Antitubercular Agents; Benzoxazines; Cyclopropanes; Drug Combinations; Drug Interactions; Ethambutol; Female; Healthy Volunteers; Humans; Isoniazid; Male; Nitroimidazoles; Oxazoles; Pyrazinamide; Rifampin | 2016 |
Anti-tuberculosis drug concentrations in tuberculosis patients with and without diabetes mellitus.
Topics: Adult; Antitubercular Agents; Diabetes Mellitus; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Tuberculosis | 2017 |
Evaluation of Proinflammatory Cytokines and Adverse Events in Healthy Volunteers upon Inhalation of Antituberculosis Drugs.
Topics: Administration, Inhalation; Adult; Antitubercular Agents; Cross-Over Studies; Double-Blind Method; Dry Powder Inhalers; Female; Healthy Volunteers; Humans; Interleukin-1beta; Isoniazid; Levofloxacin; Liposomes; Male; Peak Expiratory Flow Rate; Pyrazinamide; Rifampin; Sputum; Tumor Necrosis Factor-alpha; Young Adult | 2016 |
High-dose rifampicin, moxifloxacin, and SQ109 for treating tuberculosis: a multi-arm, multi-stage randomised controlled trial.
Topics: Adamantane; Adult; Antitubercular Agents; Drug Administration Schedule; Drug Therapy, Combination; Ethambutol; Ethylenediamines; Female; Fluoroquinolones; Humans; Isoniazid; Male; Moxifloxacin; Pyrazinamide; Rifampin; South Africa; Tanzania; Tuberculosis, Pulmonary | 2017 |
Pharmacokinetics, Tolerability, and Bacteriological Response of Rifampin Administered at 600, 900, and 1,200 Milligrams Daily in Patients with Pulmonary Tuberculosis.
Topics: Adult; Antibiotics, Antitubercular; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Pulmonary | 2017 |
Association of UGT2B7 polymorphisms with risk of induced liver injury by anti-tuberculosis drugs in Chinese Han.
Topics: Adult; Antitubercular Agents; Asian People; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Ethambutol; Female; Genetic Predisposition to Disease; Glucuronosyltransferase; Humans; Isoniazid; Male; Middle Aged; Polymorphism, Single Nucleotide; Pyrazinamide; Rifampin; Risk; Tuberculosis, Pulmonary; Young Adult | 2017 |
Biomarkers of Tuberculosis Severity and Treatment Effect: A Directed Screen of 70 Host Markers in a Randomized Clinical Trial.
Topics: Adult; Aged; Antitubercular Agents; Biomarkers; Drug Combinations; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Severity of Illness Index; Treatment Outcome; Tuberculosis, Pulmonary | 2017 |
Substitution of ethambutol with linezolid during the intensive phase of treatment of pulmonary tuberculosis: a prospective, multicentre, randomised, open-label, phase 2 trial.
Topics: Adult; Aged; Aged, 80 and over; Antitubercular Agents; Drug Substitution; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Linezolid; Male; Middle Aged; Prospective Studies; Pyrazinamide; Rifampin; Sputum; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Young Adult | 2019 |
Treatment outcomes for isoniazid-monoresistant tuberculosis in Peru, 2012-2014.
Topics: Adolescent; Adult; Child; Child, Preschool; Cross-Sectional Studies; Drug Therapy, Combination; Ethambutol; Female; Humans; Infant; Infant, Newborn; Isoniazid; Levofloxacin; Male; Middle Aged; Peru; Pyrazinamide; Retrospective Studies; Rifampin; Sex Factors; Time Factors; Tuberculosis, Multidrug-Resistant | 2018 |
Efficacy and safety of cholecalciferol-augmented anti-tuberculosis therapy for treatment of naïve patients with pulmonary tuberculosis: A randomized, controlled, clinical study.
Topics: Adult; Antitubercular Agents; Cholecalciferol; Drug Therapy, Combination; Egypt; Ethambutol; Female; Humans; Isoniazid; Male; Pyrazinamide; Rifampin; Treatment Failure; Treatment Outcome; Tuberculosis, Pulmonary; Vitamins; Young Adult | 2019 |
Evaluation of metformin in combination with rifampicin containing antituberculosis therapy in patients with new, smear-positive pulmonary tuberculosis (METRIF): study protocol for a randomised clinical trial.
Topics: Adult; Antibiotics, Antitubercular; Drug Combinations; Drug Therapy, Combination; Ethambutol; Humans; India; Isoniazid; Metformin; Multicenter Studies as Topic; Mycobacterium tuberculosis; Pyrazinamide; Randomized Controlled Trials as Topic; Rifampin; Tuberculosis, Pulmonary | 2019 |
Safety of pyrazinamide-including regimen in late elderly patients with pulmonary tuberculosis: A prospective randomized open-label study.
Topics: Age Factors; Aged, 80 and over; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Ethambutol; Female; Humans; Incidence; Isoniazid; Male; Mycobacterium tuberculosis; Prospective Studies; Pyrazinamide; Rifampin; Time Factors; Treatment Outcome; Tuberculosis, Pulmonary | 2019 |
Toxicity related to standard TB therapy for pulmonary tuberculosis and treatment outcomes in the REMoxTB study according to HIV status.
Topics: Adult; Antitubercular Agents; Ethambutol; Female; HIV Seropositivity; Humans; Incidence; Isoniazid; Linear Models; Male; Multivariate Analysis; Prospective Studies; Pyrazinamide; Rifampin; Risk Factors; Treatment Outcome; Tuberculosis, Pulmonary; United Kingdom | 2019 |
Fourteen-Day Bactericidal Activity, Safety, and Pharmacokinetics of Linezolid in Adults with Drug-Sensitive Pulmonary Tuberculosis.
Topics: Adult; Antitubercular Agents; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Linezolid; Male; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; South Africa; Sputum; Tuberculosis, Pulmonary | 2020 |
Telacebec (Q203), a New Antituberculosis Agent.
Topics: Administration, Oral; Antitubercular Agents; Dose-Response Relationship, Drug; Drug Therapy, Combination; Ethambutol; Humans; Imidazoles; Isoniazid; Mycobacterium tuberculosis; Piperidines; Pyrazinamide; Pyridines; Rifampin; Tuberculosis, Pulmonary | 2020 |
Electronic pillbox-enabled self-administered therapy versus standard directly observed therapy for tuberculosis medication adherence and treatment outcomes in Ethiopia (SELFTB): protocol for a multicenter randomized controlled trial.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Cost-Benefit Analysis; Directly Observed Therapy; Electrical Equipment and Supplies; Equivalence Trials as Topic; Ethambutol; Ethiopia; Female; Follow-Up Studies; Humans; Isoniazid; Male; Microbial Sensitivity Tests; Middle Aged; Multicenter Studies as Topic; Mycobacterium tuberculosis; Patient Acceptance of Health Care; Prospective Studies; Pyrazinamide; Randomized Controlled Trials as Topic; Rifampin; Self Administration; Sputum; Treatment Outcome; Tuberculosis, Pulmonary; Young Adult | 2020 |
Optimising pyrazinamide for the treatment of tuberculosis.
Topics: Antibiotics, Antitubercular; Antitubercular Agents; Humans; Isoniazid; Pyrazinamide; Rifampin; Tuberculosis | 2021 |
Assessing whether isoniazid is essential during the first 14 days of tuberculosis therapy: a phase 2a, open-label, randomised controlled trial.
Topics: Adult; Antitubercular Agents; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Moxifloxacin; Pyrazinamide; Rifampin; Tuberculosis | 2020 |
Efficacy and safety of combined isoniazid-rifampicin-pyrazinamide-levofloxacin dry powder inhaler in treatment of pulmonary tuberculosis: A randomized controlled trial.
Topics: Dry Powder Inhalers; Humans; Isoniazid; Levofloxacin; Powders; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 2021 |
Early Bactericidal Activity of Delpazolid (LCB01-0371) in Patients with Pulmonary Tuberculosis.
Topics: Adult; Aged; Antitubercular Agents; Drug Therapy, Combination; Humans; Isoniazid; Middle Aged; Mycobacterium tuberculosis; Oxazolidinones; Pyrazinamide; Sputum; Tuberculosis, Pulmonary; Young Adult | 2022 |
Shorter Treatment for Nonsevere Tuberculosis in African and Indian Children.
Topics: Adolescent; Africa; Antitubercular Agents; Child; Child, Preschool; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; India; Infant; Intention to Treat Analysis; Isoniazid; Male; Patient Acuity; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis | 2022 |
Safety and pharmacokinetics-pharmacodynamics of a shorter tuberculosis treatment with high-dose pyrazinamide and rifampicin: a study protocol of a phase II clinical trial (HighShort-RP).
Topics: Adult; Antitubercular Agents; Clinical Trials, Phase II as Topic; Drug Therapy, Combination; Humans; Isoniazid; Pyrazinamide; Randomized Controlled Trials as Topic; Recurrence; Rifampin; Tuberculosis | 2022 |
Treatment shortening of drug-sensitive pulmonary tuberculosis using high-dose rifampicin for 3 months after culture conversion (Hi-DoRi-3): a study protocol for an open-label randomized clinical trial.
Topics: Antitubercular Agents; Drug Therapy, Combination; Humans; Isoniazid; Multicenter Studies as Topic; Pyrazinamide; Randomized Controlled Trials as Topic; Rifampin; Treatment Outcome; Tuberculosis, Pulmonary | 2022 |
Assessing Pretomanid for Tuberculosis (APT), a Randomized Phase 2 Trial of Pretomanid-Containing Regimens for Drug-Sensitive Tuberculosis: 12-Week Results.
Topics: Animals; Antitubercular Agents; Drug Therapy, Combination; Isoniazid; Mice; Nitroimidazoles; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 2023 |
Treatment Strategy for Rifampin-Susceptible Tuberculosis.
Topics: Antitubercular Agents; Diarylquinolines; Drug Administration Schedule; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Linezolid; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 2023 |
Efficacy and safety of an innovative short-course regimen containing clofazimine for treatment of drug-susceptible tuberculosis: a clinical trial.
Topics: Antitubercular Agents; Clofazimine; Drug Therapy, Combination; Humans; Isoniazid; Prothionamide; Pyrazinamide; Treatment Outcome; Tuberculosis | 2023 |
Optimizing (O) rifapentine-based (RI) regimen and shortening (EN) the treatment of drug-susceptible tuberculosis (T) (ORIENT) using an adaptive seamless design: study protocol of a multicenter randomized controlled trial.
Topics: Clinical Trials, Phase II as Topic; Humans; Isoniazid; Moxifloxacin; Multicenter Studies as Topic; Pyrazinamide; Randomized Controlled Trials as Topic; Rifampin; Tuberculosis | 2023 |
1484 other study(ies) available for pyrazinamide and isoniazid
| Article | Year |
|---|---|
Antimycobacterial activity of substituted isosteres of pyridine- and pyrazinecarboxylic acids.
Topics: Antitubercular Agents; Coumarins; Esters; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrazines; Pyridines; Structure-Activity Relationship | 1998 |
Syntheses and evaluation of benzodiazaborine compounds against M. tuberculosis H37Rv in vitro.
Topics: Antitubercular Agents; Boron Compounds; Drug Design; Heterocyclic Compounds, 2-Ring; Indicators and Reagents; Isoniazid; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Pyrazinamide; Structure-Activity Relationship | 1998 |
A new class of antituberculosis agents.
Topics: Amides; Antitubercular Agents; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Structure-Activity Relationship; Sulfones | 2000 |
Antimycobacterial activity of substituted isosteres of pyridine- and pyrazinecarboxylic acids. 2.
Topics: Antitubercular Agents; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Oxadiazoles; Pyrazines; Pyridines; Structure-Activity Relationship | 2001 |
Anilinopyrimidines as novel antituberculosis agents.
Topics: Animals; Antimalarials; Antitubercular Agents; Cell Line, Tumor; Cell Survival; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Plasmodium falciparum; Pyrimidines; Structure-Activity Relationship | 2003 |
OPC-67683, a nitro-dihydro-imidazooxazole derivative with promising action against tuberculosis in vitro and in mice.
Topics: Animals; Antitubercular Agents; Blood; Cell Line; Humans; In Vitro Techniques; Intracellular Membranes; Macrophages; Mammals; Mice; Microbial Sensitivity Tests; Microsomes, Liver; Mycobacterium; Mycobacterium bovis; Mycolic Acids; Nitroimidazoles; Oxazoles; Treatment Outcome; Tuberculosis | 2006 |
Synergistic activity of R207910 combined with pyrazinamide against murine tuberculosis.
Topics: Animals; Antitubercular Agents; Colony Count, Microbial; Diarylquinolines; Drug Synergism; Female; Lung; Mice; Organ Size; Pyrazinamide; Quinolines; Spleen; Survival Analysis; Tuberculosis, Pulmonary | 2007 |
Low-oxygen-recovery assay for high-throughput screening of compounds against nonreplicating Mycobacterium tuberculosis.
Topics: Anti-Bacterial Agents; Antitubercular Agents; DNA, Bacterial; Drug Evaluation, Preclinical; Mycobacterium tuberculosis; Oxygen | 2007 |
A new modification of anti-tubercular active molecules.
Topics: Antitubercular Agents; Chemical Phenomena; Chemistry, Physical; Chromatography, High Pressure Liquid; Half-Life; Isoniazid; Kinetics; Lipids; Microbial Sensitivity Tests; Mycobacterium avium; Mycobacterium kansasii; Pyrazinamide; Quantitative Structure-Activity Relationship | 2007 |
Inhibition of isolated Mycobacterium tuberculosis fatty acid synthase I by pyrazinamide analogs.
Topics: Bacterial Proteins; Cell-Free System; Fatty Acid Synthases; Humans; Inhibitory Concentration 50; Kinetics; Mass Spectrometry; Molecular Structure; Mycobacterium tuberculosis; NADP; Oxidation-Reduction; Pyrazinamide; Reproducibility of Results; Substrate Specificity | 2007 |
Pyrrolidine dithiocarbamate and diethyldithiocarbamate are active against growing and nongrowing persister Mycobacterium tuberculosis.
Topics: Animals; Antitubercular Agents; Ditiocarb; Female; Mice; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrazinamide; Pyrrolidines; Rifampin; Thiocarbamates | 2007 |
Metronidazole lacks antibacterial activity in guinea pigs infected with Mycobacterium tuberculosis.
Topics: Animals; Antitubercular Agents; Colony Count, Microbial; Female; Guinea Pigs; Isoniazid; Lung; Metronidazole; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Spleen; Tuberculosis, Pulmonary | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Susceptibility of Mycobacterium bovis BCG vaccine strains to antituberculous antibiotics.
Topics: Antitubercular Agents; BCG Vaccine; Microbial Sensitivity Tests; Mycobacterium bovis | 2009 |
A microwave-assisted facile regioselective Fischer indole synthesis and antitubercular evaluation of novel 2-aryl-3,4-dihydro-2H-thieno[3,2-b]indoles.
Topics: Antitubercular Agents; Drug Resistance, Multiple, Bacterial; Indoles; Microwaves; Mycobacterium tuberculosis; Stereoisomerism; Structure-Activity Relationship | 2009 |
A facile synthesis and antimycobacterial evaluation of novel spiro-pyrido-pyrrolizines and pyrrolidines.
Topics: Anti-Bacterial Agents; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Mycobacterium Infections, Nontuberculous; Mycobacterium smegmatis; Mycobacterium tuberculosis; Piperidones; Pyrrolidines; Spiro Compounds; Tuberculosis | 2009 |
Role of porins in the susceptibility of Mycobacterium smegmatis and Mycobacterium chelonae to aldehyde-based disinfectants and drugs.
Topics: Antitubercular Agents; Disinfectants; Drug Resistance, Bacterial; Glutaral; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Mycobacterium chelonae; Mycobacterium smegmatis; o-Phthalaldehyde; Porins | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
New approach for drug susceptibility testing: monitoring the stress response of mycobacteria.
Topics: Electric Impedance; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrazinamide; Stress, Physiological | 2009 |
L-proline-catalysed facile green protocol for the synthesis and antimycobacterial evaluation of [1,4]-thiazines.
Topics: Anti-Bacterial Agents; Antitubercular Agents; Catalysis; Drug Resistance, Multiple, Bacterial; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium smegmatis; Mycobacterium tuberculosis; Proline; Thiazines | 2009 |
Novel three-component domino reactions of ketones, isatin and amino acids: synthesis and discovery of antimycobacterial activity of highly functionalised novel dispiropyrrolidines.
Topics: Amino Acids; Anti-Bacterial Agents; Isatin; Ketones; Microbial Sensitivity Tests; Models, Molecular; Molecular Conformation; Mycobacterium tuberculosis; Pyrrolidines | 2010 |
A highly atom economic, chemo-, regio- and stereoselective synthesis and evaluation of spiro-pyrrolothiazoles as antitubercular agents.
Topics: Antitubercular Agents; Crystallography, X-Ray; Drug Resistance, Multiple, Bacterial; Molecular Conformation; Mycobacterium tuberculosis; Pyrroles; Spiro Compounds; Stereoisomerism; Thiazoles | 2010 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Synthesis and antituberculosis activity of novel mefloquine-isoxazole carboxylic esters as prodrugs.
Topics: Antitubercular Agents; Carboxylic Acids; Esters; Humans; Isoxazoles; Mefloquine; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Prodrugs | 2010 |
Fast standardized therapeutic-efficacy assay for drug discovery against tuberculosis.
Topics: Acetamides; Animals; Antitubercular Agents; Aza Compounds; Disease Models, Animal; Drug Discovery; Ethambutol; Fluoroquinolones; Immunocompetence; Inhalation Exposure; Isoniazid; Linezolid; Mice; Mice, Inbred C57BL; Moxifloxacin; Oxazolidinones; Pyrazinamide; Quinolines; Reproducibility of Results; Rifampin; Tuberculosis, Pulmonary | 2010 |
Radiosynthesis and bioimaging of the tuberculosis chemotherapeutics isoniazid, rifampicin and pyrazinamide in baboons.
Topics: Animals; Antitubercular Agents; Blood Proteins; Brain; Carbon Radioisotopes; Humans; Isoniazid; Papio; Positron-Emission Tomography; Pyrazinamide; Rifampin; Thorax; Tissue Distribution | 2010 |
Selective one-pot multicomponent synthesis and anti-tubercular evaluation of 5-(aryl/cyclohexylsulfanyl)-2-alkoxy-4,6-diarylnicotinonitriles.
Topics: Antitubercular Agents; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nicotine | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Emergence and molecular characterization of extensively drug-resistant Mycobacterium tuberculosis clinical isolates from the Delhi Region in India.
Topics: Amikacin; Antitubercular Agents; Bacterial Proteins; Capreomycin; DNA Gyrase; DNA Mutational Analysis; DNA-Directed RNA Polymerases; Extensively Drug-Resistant Tuberculosis; Fluoroquinolones; India; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Point Mutation; Polymerase Chain Reaction; Rifampin | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Pyrazole derivatives from azines of substituted phenacyl aryl/cyclohexyl sulfides and their antimycobacterial activity.
Topics: Anti-Bacterial Agents; Antitubercular Agents; Dimethylformamide; Formamides; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrazoles; Sulfides | 2010 |
Synthesis and antitubercular evaluation of novel substituted aryl and thiophenyl tethered dihydro-6H-quinolin-5-ones.
Topics: Antitubercular Agents; Catalysis; Cesium; Chlorides; Crystallography, X-Ray; Microbial Sensitivity Tests; Molecular Conformation; Mycobacterium tuberculosis; Quinolones; Structure-Activity Relationship | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Synthesis and antimycobacterial activity of highly functionalized tetrahydro-4(1H)-pyridinones.
Topics: Anti-Bacterial Agents; Crystallography, X-Ray; Microbial Sensitivity Tests; Models, Molecular; Mycobacterium tuberculosis; Pyridones | 2011 |
Synthesis and antitubercular evaluation of amidoalkyl dibenzofuranols and 1H-benzo[2,3]benzofuro[4,5-e][1,3]oxazin-3(2H)-ones.
Topics: Antitubercular Agents; Benzofurans; Catalysis; Cyclization; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Oxazines; Phosphoric Acids; Polymers; Silicon Dioxide; Temperature; Urea | 2011 |
New fluorine-containing hydrazones active against MDR-tuberculosis.
Topics: Animals; Antitubercular Agents; Cell Line; Fluorine; Humans; Hydrazones; Microbial Sensitivity Tests; Mycobacterium; Mycobacterium kansasii; Plasma; Rats; Tuberculosis, Multidrug-Resistant | 2011 |
Synthesis of novel 3-cyclohexylpropanoic acid-derived nitrogen heterocyclic compounds and their evaluation for tuberculostatic activity.
Topics: Antitubercular Agents; Benzimidazoles; Cell Line; Heterocyclic Compounds; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Propionates | 2012 |
Camphorsulfonic acid catalysed facile tandem double Friedlander annulation protocol for the synthesis of phenoxy linked bisquinoline derivatives and discovery of antitubercular agents.
Topics: Animals; Antitubercular Agents; Camphor; Catalysis; Chemistry Techniques, Synthetic; Mice; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Phenols; Quinolines; Structure-Activity Relationship | 2012 |
Design, synthesis, and structure-activity correlations of novel dibenzo[b,d]furan, dibenzo[b,d]thiophene, and N-methylcarbazole clubbed 1,2,3-triazoles as potent inhibitors of Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Benzofurans; Carbazoles; Cell Line, Tumor; Click Chemistry; Cytostatic Agents; Drug Design; Humans; Mycobacterium tuberculosis; Thiophenes; Triazoles | 2012 |
Synthesis of benzimidazolyl-1,3,4-oxadiazol-2ylthio-N-phenyl (benzothiazolyl) acetamides as antibacterial, antifungal and antituberculosis agents.
Topics: Antifungal Agents; Antitubercular Agents; Bacteria; Benzothiazoles; Chemistry Techniques, Synthetic; Fungi; Microbial Sensitivity Tests; Mycobacterium tuberculosis | 2012 |
Synthesis and antimycobacterial activity of prodrugs of sulfur dioxide (SO2).
Topics: Animals; Antitubercular Agents; Hydrogen-Ion Concentration; Kinetics; Mycobacterium tuberculosis; Prodrugs; Rats; Structure-Activity Relationship; Sulfonamides; Sulfur Dioxide | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
The synthesis and antituberculosis activity of 5'-nor carbocyclic uracil derivatives.
Topics: Animals; Antitubercular Agents; Cell Survival; Chlorocebus aethiops; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Stereoisomerism; Uracil; Vero Cells | 2012 |
Anti-infective and herbicidal activity of N-substituted 2-aminobenzothiazoles.
Topics: Anti-Infective Agents; Antifungal Agents; Antineoplastic Agents; Benzothiazoles; Cell Line, Tumor; Chloroplasts; Drug Screening Assays, Antitumor; Herbicides; Humans; Microbial Sensitivity Tests; Spinacia oleracea; Structure-Activity Relationship | 2012 |
Molecular hybridization of bioactives: synthesis and antitubercular evaluation of novel dibenzofuran embodied homoisoflavonoids via Baylis-Hillman reaction.
Topics: Antitubercular Agents; Biological Products; Chromones; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship | 2012 |
Synthesis and antimycobacterial evaluation of pyrazinamide derivatives with benzylamino substitution.
Topics: Antitubercular Agents; Benzylamines; Cells, Cultured; Humans; Inhibitory Concentration 50; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium; Pyrazinamide | 2013 |
Synthesis and antimycobacterial evaluation of N-substituted 5-chloropyrazine-2-carboxamides.
Topics: Amides; Anti-Bacterial Agents; Antitubercular Agents; Mycobacterium tuberculosis; Pyrazines; Structure-Activity Relationship | 2013 |
Inhibition of Mycobacterium tuberculosis strains H37Rv and MDR MS-115 by a new set of C5 modified pyrimidine nucleosides.
Topics: Animals; Antitubercular Agents; Cell Line, Tumor; Cell Survival; Chlorocebus aethiops; Humans; Jurkat Cells; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrimidine Nucleosides; Structure-Activity Relationship; Vero Cells | 2013 |
Design, synthesis and antitubercular evaluation of novel 2-substituted-3H-benzofuro benzofurans via palladium-copper catalysed Sonagashira coupling reaction.
Topics: Animals; Antitubercular Agents; Benzofurans; Catalysis; Copper; Drug Design; Heterocyclic Compounds, 4 or More Rings; Humans; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Palladium; Structure-Activity Relationship | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Rational design, synthesis and antitubercular evaluation of novel 2-(trifluoromethyl)phenothiazine-[1,2,3]triazole hybrids.
Topics: Antitubercular Agents; Click Chemistry; Dose-Response Relationship, Drug; Drug Design; HEK293 Cells; Humans; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship; Thiazines; Triazoles | 2014 |
Alkylamino derivatives of pyrazinamide: synthesis and antimycobacterial evaluation.
Topics: Anti-Bacterial Agents; Antifungal Agents; Antitubercular Agents; Crystallography; Drug Evaluation, Preclinical; Hep G2 Cells; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrazinamide | 2014 |
Design, synthesis and evaluation of 1,2,3-triazole-adamantylacetamide hybrids as potent inhibitors of Mycobacterium tuberculosis.
Topics: Acetamides; Adamantane; Antitubercular Agents; Click Chemistry; Drug Design; HEK293 Cells; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Structure-Activity Relationship; Triazoles | 2014 |
Facile synthesis of benzonitrile/nicotinonitrile based s-triazines as new potential antimycobacterial agents.
Topics: Anti-Bacterial Agents; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Nicotinic Acids; Nitriles; Structure-Activity Relationship; Triazines | 2014 |
Synthesis and antituberculosis activity of novel 5-styryl-4-(hetero)aryl-pyrimidines via combination of the Pd-catalyzed Suzuki cross-coupling and S(N)(H) reactions.
Topics: Animals; Antitubercular Agents; Catalysis; Dose-Response Relationship, Drug; Mice; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Palladium; Pyrimidines; Structure-Activity Relationship | 2014 |
New class of methyl tetrazole based hybrid of (Z)-5-benzylidene-2-(piperazin-1-yl)thiazol-4(%H)-one as potent antitubercular agents.
Topics: Animals; Antitubercular Agents; Chlorocebus aethiops; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship; Tetrazoles; Thiazoles; Vero Cells | 2014 |
Synthesis and antimycobacterial evaluation of 5-alkylamino-N-phenylpyrazine-2-carboxamides.
Topics: Amides; Anti-Bacterial Agents; Antitubercular Agents; Humans; Pyrazinamide; Structure-Activity Relationship; Tuberculosis | 2015 |
Synthesis and evaluation of in vitro antimycobacterial activity of novel 1H-benzo[d]imidazole derivatives and analogues.
Topics: Animals; Antitubercular Agents; Benzimidazoles; Cell Line; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium bovis; Mycobacterium tuberculosis; Structure-Activity Relationship; Swine | 2015 |
Novel amide and sulphonamide derivatives of 6-(piperazin-1-yl)phenanthridine as potent Mycobacterium tuberculosis H37Rv inhibitors.
Topics: Amides; Animals; Antitubercular Agents; Cell Line; Crystallography, X-Ray; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydrolases; Macrophages; Mice; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Mycobacterium tuberculosis; Phenanthridines; Piperazines; Structure-Activity Relationship | 2015 |
Thermodynamic equilibrium solubility measurements in simulated fluids by 96-well plate method in early drug discovery.
Topics: Drug Discovery; Pharmaceutical Preparations; Solubility; Thermodynamics | 2015 |
Synthesis and biological evaluation of new imidazo[2,1-b][1,3,4]thiadiazole-benzimidazole derivatives.
Topics: Animals; Antifungal Agents; Antioxidants; Antitubercular Agents; Benzimidazoles; Cell Survival; Chlorocebus aethiops; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Structure-Activity Relationship; Thiadiazoles; Tuberculosis; Vero Cells | 2015 |
Novel 2-(2-phenalkyl)-1H-benzo[d]imidazoles as antitubercular agents. Synthesis, biological evaluation and structure-activity relationship.
Topics: Animals; Antitubercular Agents; Benzimidazoles; Cell Line; Cell Proliferation; Dose-Response Relationship, Drug; Humans; Mice; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship | 2015 |
Thiophene containing trisubstituted methanes [TRSMs] as identified lead against Mycobacterium tuberculosis.
Topics: Animals; Anti-Bacterial Agents; Chlorocebus aethiops; Drug Design; Drug Resistance, Bacterial; Drug Resistance, Multiple; Humans; Methane; Mice; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Rats; Thiophenes; Vero Cells | 2015 |
Synthesis, and structure-activity relationship for C(4) and/or C(5) thienyl substituted pyrimidines, as a new family of antimycobacterial compounds.
Topics: Animals; Antitubercular Agents; Drug Resistance; Inhibitory Concentration 50; Mice; Molecular Structure; Mycobacterium tuberculosis; Pyrimidines; Structure-Activity Relationship; Ticrynafen | 2015 |
Design of novel dispirooxindolopyrrolidine and dispirooxindolopyrrolothiazole derivatives as potential antitubercular agents.
Topics: Animals; Antitubercular Agents; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Drug Design; Mice; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Pyrrolidines; Spiro Compounds; Structure-Activity Relationship; Thiazoles | 2015 |
One-pot synthesis of new triazole--Imidazo[2,1-b][1,3,4]thiadiazole hybrids via click chemistry and evaluation of their antitubercular activity.
Topics: Antitubercular Agents; Click Chemistry; Crystallography, X-Ray; Dose-Response Relationship, Drug; Imidazoles; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship; Thiadiazoles; Triazoles | 2015 |
New INH-pyrazole analogs: Design, synthesis and evaluation of antitubercular and antibacterial activity.
Topics: Anti-Bacterial Agents; Antitubercular Agents; Bacteria; Binding Sites; Drug Design; Inhibitory Concentration 50; Isoniazid; Microbial Sensitivity Tests; Models, Molecular; Molecular Docking Simulation; Molecular Structure; Mycobacterium tuberculosis; Pyrazoles | 2015 |
Synthesis and docking studies of pyrazine-thiazolidinone hybrid scaffold targeting dormant tuberculosis.
Topics: Antitubercular Agents; Molecular Docking Simulation; Pyrazines; Thiazolidines | 2016 |
Benzo[d]thiazol-2-yl(piperazin-1-yl)methanones as new anti-mycobacterial chemotypes: Design, synthesis, biological evaluation and 3D-QSAR studies.
Topics: Animals; Antitubercular Agents; Chemistry Techniques, Synthetic; Drug Design; Mice; Microbial Sensitivity Tests; Models, Molecular; Molecular Conformation; Mycobacterium tuberculosis; Piperazine; Piperazines; Quantitative Structure-Activity Relationship; RAW 264.7 Cells | 2016 |
Synthesis, biological evaluation and structure-activity relationship of 2-styrylquinazolones as anti-tubercular agents.
Topics: Antitubercular Agents; Cell Survival; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Mycobacterium tuberculosis; Quinazolines; Structure-Activity Relationship | 2016 |
Click-based synthesis and antitubercular evaluation of novel dibenzo[b,d]thiophene-1,2,3-triazoles with piperidine, piperazine, morpholine and thiomorpholine appendages.
Topics: Antitubercular Agents; Cell Survival; Click Chemistry; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Molecular Structure; Morpholines; Mycobacterium tuberculosis; Piperazine; Piperazines; Piperidines; Structure-Activity Relationship; Thiophenes; Triazoles | 2016 |
Synthesis and antitubercular evaluation of novel dibenzo[b,d]thiophene tethered imidazo[1,2-a]pyridine-3-carboxamides.
Topics: Antitubercular Agents; Cell Proliferation; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Imidazoles; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Pyridines; Structure-Activity Relationship; Thiophenes | 2016 |
Click-based synthesis and antitubercular evaluation of dibenzofuran tethered thiazolyl-1,2,3-triazolyl acetamides.
Topics: Acetamides; Animals; Antitubercular Agents; Benzofurans; Cell Proliferation; Click Chemistry; Dose-Response Relationship, Drug; Mice; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; RAW 264.7 Cells; Structure-Activity Relationship | 2016 |
Synthesis and evaluation of antitubercular activity of fluorinated 5-aryl-4-(hetero)aryl substituted pyrimidines.
Topics: Antitubercular Agents; Fluorine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Microbial Sensitivity Tests; Mycobacterium; Pyrimidines | 2016 |
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
Synthesis and biological activity of furoxan derivatives against Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Cell Line, Tumor; Chemistry Techniques, Synthetic; Drug Design; Humans; Mycobacterium tuberculosis; Oxadiazoles | 2016 |
Amphiphilic xanthones as a potent chemical entity of anti-mycobacterial agents with membrane-targeting properties.
Topics: Adenosine Triphosphate; Animals; Antitubercular Agents; Biological Availability; Cell Membrane; Cytochrome P-450 Enzyme Inhibitors; Drug Design; Hydrophobic and Hydrophilic Interactions; Kinetics; Mycobacterium tuberculosis; Rats; Xanthones | 2016 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Design, development of new synthetic methodology, and biological evaluation of substituted quinolines as new anti-tubercular leads.
Topics: Antitubercular Agents; Dose-Response Relationship, Drug; Drug Design; HEK293 Cells; Humans; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Quinolines; Structure-Activity Relationship; Tuberculosis | 2016 |
Synthesis, screening and docking analysis of hispolon analogs as potential antitubercular agents.
Topics: Antitubercular Agents; Catechols; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship | 2017 |
Synthesis and biological evaluation of novel 5-aryl-4-(5-nitrofuran-2-yl)-pyrimidines as potential anti-bacterial agents.
Topics: Anti-Bacterial Agents; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Molecular Structure; Neisseria gonorrhoeae; Nitro Compounds; Pyrimidines; Staphylococcus aureus; Structure-Activity Relationship | 2017 |
New hydrazides derivatives of isoniazid against Mycobacterium tuberculosis: Higher potency and lower hepatocytotoxicity.
Topics: Animals; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Hep G2 Cells; Humans; Hydrazines; Isoniazid; Macrophages; Mice; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship | 2018 |
Dibenzofuran, dibenzothiophene and N-methyl carbazole tethered 2-aminothiazoles and their cinnamamides as potent inhibitors of Mycobacterium tuberculosis.
Topics: Anti-Bacterial Agents; Benzofurans; Carbazoles; Cell Survival; Cinnamates; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship; Thiazoles; Thiophenes | 2018 |
Benzo[d]thiazole-2-carbanilides as new anti-TB chemotypes: Design, synthesis, biological evaluation, and structure-activity relationship.
Topics: Animals; Antitubercular Agents; Carbanilides; Cell Survival; Dose-Response Relationship, Drug; Drug Design; Mice; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Mycobacterium tuberculosis; RAW 264.7 Cells; Structure-Activity Relationship; Thiazoles | 2018 |
Design, synthesis, molecular-docking and antimycobacterial evaluation of some novel 1,2,3-triazolyl xanthenones.
Topics: | 2017 |
Molecular hybridization approach for phenothiazine incorporated 1,2,3-triazole hybrids as promising antimicrobial agents: Design, synthesis, molecular docking and in silico ADME studies.
Topics: Adsorption; Animals; Anti-Bacterial Agents; Chlorocebus aethiops; Dose-Response Relationship, Drug; Drug Design; Escherichia coli; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Phenothiazines; Pseudomonas aeruginosa; Staphylococcus aureus; Structure-Activity Relationship; Triazoles; Vero Cells | 2019 |
4-Substituted picolinohydrazonamides as a new class of potential antitubercular agents.
Topics: Animals; Antitubercular Agents; Bacteria; Humans; Mice; Microbial Sensitivity Tests; Molecular Structure; Pyridines; Thiosemicarbazones; Yeasts | 2020 |
Synthesis, antitubercular and anticancer activity of new Baylis-Hillman adduct-derived
Topics: | 2014 |
Multiple biological active 4-aminopyrazoles containing trifluoromethyl and their 4-nitroso-precursors: Synthesis and evaluation.
Topics: Animals; Bacteria; Drug Screening Assays, Antitumor; Epidermophyton; HeLa Cells; Humans; Mice; Microbial Sensitivity Tests; Molecular Structure; Nitroso Compounds; Pyrazoles; Rats, Sprague-Dawley; Structure-Activity Relationship; Trichophyton | 2020 |
Synthesis and biological evaluation of anti-tubercular activity of Schiff bases of 2-Amino thiazoles.
Topics: Amination; Antitubercular Agents; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Schiff Bases; Thiazoles; Tuberculosis | 2020 |
Microwave assisted regioselective synthesis of quinoline appended triazoles as potent anti-tubercular and antifungal agents via copper (I) catalyzed cycloaddition.
Topics: Antifungal Agents; Antitubercular Agents; Aspergillus; Candida albicans; Catalysis; Cell Survival; Copper; Cycloaddition Reaction; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Microbial Sensitivity Tests; Microwaves; Molecular Structure; Mycobacterium tuberculosis; Quinolines; Stereoisomerism; Structure-Activity Relationship; Triazoles | 2021 |
Design, synthesis and molecular docking studies of imidazole and benzimidazole linked ethionamide derivatives as inhibitors of InhA and antituberculosis agents.
Topics: Antitubercular Agents; Benzimidazoles; Dose-Response Relationship, Drug; Drug Design; Ethionamide; Humans; Imidazoles; Inhibins; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship | 2022 |
Tuberculosis in the 1980s: a case for short-course chemotherapy.
Topics: Animals; Drug Administration Schedule; Drug Resistance, Microbial; Drug Therapy, Combination; Ethambutol; Humans; Hydrogen-Ion Concentration; Isoniazid; Mice; New Zealand; Pyrazinamide; Rifampin; Tuberculosis | 1979 |
Short-course chemotherapy for pulmonary tuberculosis.
Topics: Africa, Eastern; Aminosalicylic Acids; Antitubercular Agents; Drug Resistance, Microbial; Drug Therapy, Combination; Follow-Up Studies; Isoniazid; Mycobacterium tuberculosis; Prognosis; Pyrazinamide; Recurrence; Rifampin; Sputum; Streptomycin; Thioacetazone; Time Factors; Tuberculosis, Pulmonary | 1975 |
Side effects of drugs used to treat tuberculosis.
Topics: Aminosalicylic Acids; Animals; Antitubercular Agents; Capreomycin; Chemical and Drug Induced Liver Injury; Cycloserine; Deafness; Drug Hypersensitivity; Ethambutol; Ethionamide; Gastrointestinal Diseases; Goiter; Humans; Isoniazid; Kanamycin; Liver; Mental Disorders; Mice; Nervous System Diseases; Pyrazinamide; Rifampin; Streptomycin; Thioacetazone; Tuberculosis; Viomycin | 1975 |
Short-course chemotherapy for pulmonary tuberculosis.
Topics: Antitubercular Agents; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; Isoniazid; Pyrazinamide; Rifampin; Streptomycin; Thioacetazone; Time Factors; Tuberculosis, Pulmonary | 1975 |
Hepatic complications of antituberculous therapy.
Topics: Aminosalicylic Acids; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Ethambutol; Ethionamide; Female; Gastrointestinal Diseases; Humans; Isoniazid; Jaundice; Lymphatic Diseases; Male; Pyrazinamide; Skin Diseases; Streptomycin; Thioacetazone; Tuberculosis, Pulmonary | 1975 |
The treatment of tuberculosis.
Topics: Aminosalicylic Acids; Capreomycin; Ethambutol; Ethionamide; Humans; Isoniazid; Prothionamide; Pyrazinamide; Rifampin; Streptomycin; Thioacetazone; Tuberculosis | 1975 |
Editorial: Treatment of tuberculous meningitis.
Topics: Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Meningeal | 1976 |
Short-course treatment in pulmonary tuberculosis.
Topics: Adolescent; Humans; Isoniazid; Pyrazinamide; Rifampin; Streptomycin; Thioacetazone; Time Factors; Tuberculosis, Pulmonary | 1977 |
Short-course (6-month) treatment of pulmonary tuberculosis (Second East African/British Medical Research Council Study).
Topics: Africa, Eastern; Drug Therapy, Combination; Humans; Isoniazid; Pyrazinamide; Rifampin; Streptomycin; Thioacetazone; Time Factors; Tuberculosis, Pulmonary | 1976 |
Short-term chemotherapy of pulmonary tuberculosis. A controlled trial. The Research Committee of the Tuberculosis Association of India.
Topics: Drug Therapy, Combination; Ethambutol; Humans; India; Isoniazid; Pyrazinamide; Streptomycin; Thioacetazone; Tuberculosis, Pulmonary | 1976 |
Short-course chemotherapy for tuberculosis.
Topics: Adult; Ambulatory Care; Drug Administration Schedule; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Pyrazinamide; Rifampin; South Africa; Streptomycin; Time Factors; Tuberculosis, Pulmonary | 1979 |
Basic mechanisms of chemotherapy.
Topics: Aminosalicylic Acid; Animals; Antitubercular Agents; Drug Resistance, Microbial; Drug Therapy, Combination; Ethambutol; Guinea Pigs; Humans; In Vitro Techniques; Isoniazid; Mice; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Streptomycin; Thioacetazone; Tuberculosis, Pulmonary | 1979 |
The cost of antituberculous drug regimens.
Topics: Antitubercular Agents; Biological Availability; Drug Administration Schedule; Drug Therapy; Humans; Isoniazid; Long-Term Care; Pyrazinamide; Rifampin; Tuberculosis | 1979 |
Tuberculosis: genitourinary tuberculosis.
Topics: Cystoscopy; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Isoniazid; Methods; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Urogenital; Urine | 1979 |
Adverse reactions to short-course regimens containing streptomycin, isoniazid, pyrazinamide and rifampicin in Hong Kong.
Topics: Aminosalicylic Acids; Arthritis; Chemical and Drug Induced Liver Injury; Drug Eruptions; Drug Therapy, Combination; Gastrointestinal Diseases; Hong Kong; Humans; Isoniazid; Labyrinth Diseases; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Pulmonary | 1976 |
Recent advances in antituberculosis chemotherapy.
Topics: Antitubercular Agents; Ethambutol; Humans; Isoniazid; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Pulmonary | 1979 |
Bactericidal activity of streptomycin, isoniazid, rifampin, ethambutol, and pyrazinamide alone and in combination against Mycobacterium Tuberculosis.
Topics: Drug Interactions; Drug Therapy, Combination; Ethambutol; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Streptomycin | 1977 |
Silicosis and tuberculosis.
Topics: Adult; Aminosalicylic Acid; Antitubercular Agents; Ethambutol; Ethionamide; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Radiography; Recurrence; Silicotuberculosis; Streptomycin; Time Factors | 1979 |
[Therapy of tuberculosis].
Topics: Alanine Transaminase; Aspartate Aminotransferases; Drug Resistance, Microbial; Ethambutol; Humans; Isoniazid; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Pulmonary | 1979 |
Genitourinary tuberculosis: a 7-year review.
Topics: Adolescent; Adult; Aged; Drug Therapy, Combination; Ethambutol; Female; Follow-Up Studies; Forecasting; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Time Factors; Tuberculosis, Urogenital | 1979 |
Modern management of tuberculosis.
Topics: Adolescent; Adult; Aminosalicylic Acid; Child; Cycloserine; Drug Administration Schedule; Drug Therapy, Combination; Ethambutol; Ethionamide; Humans; Isoniazid; Male; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Pulmonary | 1979 |
Principles of the chemotherapy of tuberculosis.
Topics: Aminosalicylic Acid; Ethambutol; Female; Humans; Isoniazid; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Urogenital | 1977 |
The treatment of tuberculous meningitis.
Topics: Aminosalicylic Acid; Antitubercular Agents; Drug Evaluation; Drug Therapy, Combination; Ethambutol; Ethionamide; Humans; Isoniazid; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Meningeal | 1978 |
[Intermittent chemotherapy of pulmonary tuberculosis (review of the literature)].
Topics: Aminosalicylic Acid; Antitubercular Agents; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Pulmonary | 1978 |
[Results of a cooperative international questionnaire on the cost of antitubercular drugs].
Topics: Antitubercular Agents; Costs and Cost Analysis; Ethambutol; Ethionamide; Isoniazid; Pyrazinamide; Rifampin; Streptomycin | 1978 |
Cycloserine plus ethionamide plus pyrazinamide in the treatment of patients excreting isoniazid-resistant tubercle bacilli following previous chemotherapy.
Topics: Adult; Cycloserine; Drug Resistance, Microbial; Drug Therapy, Combination; Ethionamide; Female; Humans; Isoniazid; Male; Middle Aged; Mycobacterium tuberculosis; Pyrazinamide; Tuberculosis, Pulmonary | 1976 |
Management of tuberculosis: altered role of the primary care physician.
Topics: Adolescent; Adult; Aminosalicylic Acid; Antitubercular Agents; Child; Cycloserine; Ethambutol; Ethionamide; Humans; Isoniazid; Pyrazinamide; Rifampin; Streptomycin; Tuberculin Test; Tuberculosis, Pulmonary | 1977 |
Controlled trial of 6-month and 9-month regimens of daily and intermittent streptomycin plus isoniazid plus pyrazinamide for pulmonary tuberculosis in Hong Kong. The results up to 30 months.
Topics: Adolescent; Adult; Drug Administration Schedule; Drug Evaluation; Drug Resistance, Microbial; Hong Kong; Humans; Isoniazid; Pyrazinamide; Recurrence; Streptomycin; Time Factors; Tuberculosis, Pulmonary | 1977 |
[Chemotherapy of lung tuberculosis].
Topics: Cyclacillin; Ethambutol; Ethionamide; Humans; Isoniazid; Pyrazinamide; Streptomycin; Tuberculosis, Pulmonary | 1977 |
Letter: Tuberculosis care in general hospitals: Arizona's experience.
Topics: Economics, Medical; Hospitalization; Humans; Isoniazid; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Pulmonary | 1976 |
Hong Kong tuberculosis treatment services/British Medical Research Council Study of 6- and 9-month regimens of daily and intermittent streptomycin, isoniazid and pyrazinamide for pulmonary tuberculosis.
Topics: Adult; Hong Kong; Humans; Isoniazid; Pyrazinamide; Streptomycin; Time Factors; Tuberculosis, Pulmonary; United Kingdom | 1976 |
Proceedings: Latest results of East African/British Medical Research Council short course chemotherapy studies.
Topics: Drug Evaluation; Humans; Isoniazid; Pyrazinamide; Recurrence; Rifampin; Streptomycin; Tuberculosis | 1975 |
Hong Kong Tuberculosis Treatment Services/British Medical Research Council study of short-course regimens of streptomycin, isoniazid and pyrazinamide: latest results.
Topics: Adult; Drug Evaluation; Humans; Isoniazid; Pyrazinamide; Streptomycin; Tuberculosis, Pulmonary | 1975 |
The penetration of dapsone, rifampicin, isoniazid and pyrazinamide into peripheral nerves.
Topics: Animals; Dapsone; Dogs; Isoniazid; Peripheral Nerves; Pyrazinamide; Rifampin; Sciatic Nerve; Sheep; Time Factors | 1975 |
Editorial: Rifampin in tuberculous meningitis.
Topics: Child; Child, Preschool; Drug Hypersensitivity; Drug Interactions; Drug Therapy, Combination; Humans; Infant; Isoniazid; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Meningeal | 1975 |
Rationale for chemotherapy of tuberculosis and current recommendations.
Topics: Antitubercular Agents; Child; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Streptomycin; Time Factors; Tuberculosis | 1992 |
Tolerance of ofloxacin in the treatment of pulmonary tuberculosis in presence of hepatic dysfunction.
Topics: Adult; Aged; Aged, 80 and over; Chemical and Drug Induced Liver Injury; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Isoniazid; Liver Function Tests; Male; Middle Aged; Ofloxacin; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Pulmonary | 1992 |
Fixed dose combination short course chemotherapy in the treatment of pulmonary tuberculosis.
Topics: Adolescent; Adult; Aged; Drug Combinations; Drug Therapy, Combination; Humans; Isoniazid; Middle Aged; Mycobacterium tuberculosis; Patient Compliance; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 1992 |
Prospective analysis of short course chemotherapy in female genital tuberculosis.
Topics: Adult; Antitubercular Agents; Drug Therapy, Combination; Female; Humans; Isoniazid; Middle Aged; Prospective Studies; Pyrazinamide; Rifampin; Streptomycin; Time Factors; Treatment Outcome; Tuberculosis, Female Genital | 1992 |
Case holding in patients with tuberculosis in Botswana.
Topics: Botswana; Drug Therapy, Combination; Humans; Isoniazid; National Health Programs; Patient Compliance; Primary Health Care; Pyrazinamide; Rifampin; Time Factors; Tuberculosis; Tuberculosis, Pulmonary | 1992 |
[Evaluation of the treatment of adult tuberculous meningitis].
Topics: Adolescent; Adult; Antitubercular Agents; Drug Therapy, Combination; Female; Humans; Intracranial Pressure; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Streptomycin; Survival Rate; Tuberculosis, Meningeal | 1992 |
[Therapy of pulmonary tuberculosis].
Topics: Adult; Antitubercular Agents; Ethambutol; Female; Follow-Up Studies; Humans; Inpatients; Isoniazid; Male; Outpatients; Pregnancy; Prothionamide; Pyrazinamide; Rifampin; Streptomycin; Time Factors; Tuberculosis, Pulmonary | 1992 |
Intensive short course chemotherapy for tuberculous meningitis.
Topics: Antitubercular Agents; Child; Child, Preschool; Drug Administration Schedule; Drug Therapy, Combination; Ethambutol; Female; Humans; Infant; Isoniazid; Male; Prospective Studies; Pyrazinamide; Rifampin; Streptomycin; Treatment Outcome; Tuberculosis, Meningeal | 1992 |
Reactivation of tuberculous lymphadenitis during pregnancy.
Topics: Adult; Female; Humans; Isoniazid; Mycobacterium tuberculosis; Pregnancy; Pregnancy Complications, Infectious; Pyrazinamide; Recurrence; Rifampin; Risk Factors; Tuberculosis, Lymph Node; United Kingdom | 1992 |
Tuberculosis in the 1990's: resurgence, regimens, and resources.
Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Child; Drug Administration Schedule; Drug Interactions; Drug Resistance, Microbial; Drug Therapy, Combination; Ethambutol; False Negative Reactions; Humans; Isoniazid; Pyrazinamide; Radiography, Thoracic; Rifampin; Risk Factors; Streptomycin; Tuberculosis; United States | 1992 |
Antagonism between isoniazid and the combination pyrazinamide-rifampin against tuberculosis infection in mice.
Topics: Animals; Colony Count, Microbial; Drug Combinations; Female; Isoniazid; Mice; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Spleen; Tuberculosis | 1992 |
Transmission of multidrug-resistant tuberculosis among immunocompromised persons in a correctional system--New York, 1991.
Topics: Antitubercular Agents; Drug Resistance, Microbial; Ethambutol; Ethionamide; HIV Seropositivity; Humans; Immunocompromised Host; Isoniazid; Kanamycin; Mycobacterium tuberculosis; New York; Prisons; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis | 1992 |
From the Centers for Disease Control. Transmission of multidrug-resistant tuberculosis among immunocompromised persons, correctional system--New York, 1991.
Topics: Antitubercular Agents; Drug Resistance, Microbial; Ethambutol; Ethionamide; HIV Seropositivity; Humans; Immunocompromised Host; Isoniazid; Kanamycin; Mycobacterium tuberculosis; New York; Prisons; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis | 1992 |
Contemporary management of cervical tuberculosis.
Topics: Adult; Aged; Aged, 80 and over; Biopsy; Biopsy, Needle; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Mycobacterium tuberculosis; Neck; Pyrazinamide; Recurrence; Retrospective Studies; Rifampin; Sputum; Streptomycin; Tuberculin Test; Tuberculosis, Lymph Node | 1992 |
Effect of simultaneous isoniazid administration on pharmacokinetic parameters of pyrazinamide.
Topics: Adult; Drug Therapy, Combination; Female; Humans; Isoniazid; Male; Metabolic Clearance Rate; Middle Aged; Pyrazinamide; Time Factors; Tuberculosis, Pulmonary | 1991 |
Stability of isoniazid, rifampin and pyrazinamide in suspensions used for the treatment of tuberculosis in children.
Topics: Ascorbic Acid; Child; Chromatography, High Pressure Liquid; Drug Stability; Humans; Isoniazid; Pyrazinamide; Rifampin; Suspensions; Temperature; Tuberculosis | 1991 |
AIDS and tuberculosis in Spain. A report of 140 cases.
Topics: Acquired Immunodeficiency Syndrome; Drug Therapy, Combination; Ethambutol; Female; Humans; Incidence; Isoniazid; Male; Prospective Studies; Pyrazinamide; Retrospective Studies; Rifampin; Risk Factors; Spain; Streptomycin; Substance Abuse, Intravenous; Tuberculosis; Tuberculosis, Pulmonary | 1991 |
[Standardized controlled antitubercular therapy and results in 755 patients].
Topics: Adult; Aged; Antitubercular Agents; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Recurrence; Rifampin; Sputum; Streptomycin; Tuberculosis, Pulmonary | 1991 |
[Tuberculosis of the larynx, oral cavity and pharynx].
Topics: Adult; Diagnosis, Differential; Drug Therapy, Combination; Endoscopy; Ethambutol; Humans; Isoniazid; Male; Pharyngeal Diseases; Pharyngeal Neoplasms; Pyrazinamide; Rifampin; Tuberculosis; Tuberculosis, Laryngeal; Tuberculosis, Oral | 1991 |
[Effectiveness of tocopherol and anti-hypoxic agents in liver damage caused by antitubercular agents].
Topics: Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Hepatitis, Animal; Inosine Diphosphate; Isoniazid; Male; Piracetam; Pyrazinamide; Rats; Rifampin; Vitamin E | 1991 |
Treatment of tuberculosis in patients with advanced human immunodeficiency virus infection.
Topics: Acquired Immunodeficiency Syndrome; Adult; Drug Administration Schedule; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Mycobacterium tuberculosis; Pyrazinamide; Retrospective Studies; Rifampin; Sputum; Tuberculosis; Tuberculosis, Pulmonary | 1991 |
Evidence that vesicles containing living, virulent Mycobacterium tuberculosis or Mycobacterium avium in cultured human macrophages are not acidic.
Topics: Ammonium Chloride; Cell Fusion; Cells, Cultured; Chloroquine; Humans; Hydrogen-Ion Concentration; Isoniazid; Macrophages; Mycobacterium avium; Mycobacterium tuberculosis; Pyrazinamide; Streptomycin; Virulence | 1991 |
Short course chemotherapy for pulmonary tuberculosis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Self Administration; Time Factors; Tuberculosis, Pulmonary | 1991 |
The management of pulmonary tuberculosis in adults notified in England and Wales in 1988. The British Thoracic Society Research Committee and the Medical Research Council Cardiothoracic Epidemiology Group.
Topics: Antitubercular Agents; Drug Administration Schedule; Drug Therapy, Combination; England; Humans; Isoniazid; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary; Wales | 1991 |
Efficacy of intermittent pyrazinamide in experimental murine tuberculosis.
Topics: Animals; Colony Count, Microbial; Drug Administration Schedule; Drug Therapy, Combination; Isoniazid; Lung; Mice; Mice, Inbred Strains; Pyrazinamide; Spleen; Tuberculosis, Pulmonary; Tuberculosis, Splenic | 1991 |
The disposition of antituberculous drugs in plasma of elderly patients. I. Isoniazid and hydrazine metabolite.
Topics: Acetylation; Adult; Aged; Aged, 80 and over; Aging; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 1991 |
The disposition of antituberculous drugs in plasma of elderly patients. II. Isoniazid, rifampicin and pyrazinamide.
Topics: Adult; Aged; Aged, 80 and over; Aging; Female; Humans; Isoniazid; Male; Metabolic Clearance Rate; Middle Aged; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 1991 |
Effect of steroids on cerebrospinal fluid penetration of antituberculous drugs in tuberculous meningitis.
Topics: Adult; Aged; Antitubercular Agents; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Steroids; Streptomycin; Tuberculosis, Meningeal | 1991 |
Chromosomal aberrations in tuberculosis patients before and after treatment with short-term chemotherapy.
Topics: Chromosome Aberrations; Drug Therapy, Combination; Humans; Isoniazid; Mutagens; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Pulmonary | 1991 |
Interaction between carbamazepine and antituberculosis agents.
Topics: Antitubercular Agents; Carbamazepine; Drug Interactions; Drug Therapy, Combination; Female; Humans; Isoniazid; Middle Aged; Pyrazinamide | 1991 |
Hepatoxic reaction to antituberculous drugs: Adjustments to therapeutic regimen.
Topics: Antitubercular Agents; Chemical and Drug Induced Liver Injury; Clinical Protocols; Humans; Isoniazid; Liver Diseases; Pyrazinamide; Rifampin | 1991 |
Rapid liquid chromatographic method for the estimation of isoniazid and pyrazinamide in plasma and urine.
Topics: Chromatography, Liquid; Humans; Isoniazid; Pyrazinamide | 1990 |
A 62-dose, 6-month therapy for pulmonary and extrapulmonary tuberculosis. A twice-weekly, directly observed, and cost-effective regimen.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Aspartate Aminotransferases; Cost-Benefit Analysis; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Recurrence; Rifampin; Sputum; Streptomycin; Tuberculosis; Tuberculosis, Pulmonary | 1990 |
[In 76% of patients with active tuberculosis treated with triple therapy (isoniazid-rifampicin-pyrazinamide) cultural conversion precedes microscopic conversion].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Drug Therapy, Combination; Female; Humans; Isoniazid; Male; Middle Aged; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Sputum; Tuberculosis, Pulmonary | 1990 |
Use of a radiometric technique for rapid sensitivity testing of mycobacteria in Scotland: the first year's experience.
Topics: Carbon Radioisotopes; Culture Media; Drug Resistance, Microbial; Egg Proteins; Ethambutol; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrazinamide; Radiometry; Rifampin; Scotland | 1990 |
Inhibition of tubercle bacilli in cultured human macrophages by chloroquine used alone and in combination with streptomycin, isoniazid, pyrazinamide, and two metabolites of vitamin D3.
Topics: Adult; Calcifediol; Calcitriol; Chloroquine; Culture Media; Female; Humans; In Vitro Techniques; Isoniazid; Macrophages; Male; Middle Aged; Mycobacterium tuberculosis; Pyrazinamide; Streptomycin | 1990 |
Any questions? How should a patient be managed who is being treated for sputum positive pulmonary tuberculosis and becomes jaundiced in the third week of chemotherapy?
Topics: Antitubercular Agents; Drug Therapy, Combination; Humans; Isoniazid; Jaundice; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 1990 |
Effects of two pulmonary tuberculosis drug treatments and acetylator status on liver function in a Zimbabwean population.
Topics: Alanine Transaminase; Alkaline Phosphatase; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Humans; Isoniazid; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Pulmonary; Zimbabwe | 1990 |
Brain stem tuberculoma in adult patients: diagnosis and treatment.
Topics: Adult; Brain Diseases; Drug Therapy, Combination; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Streptomycin; Tomography, X-Ray Computed; Tuberculoma | 1990 |
Tuberculous meningitis. Short course of chemotherapy.
Topics: Adolescent; Adult; Aged; Child; Drug Combinations; Female; Humans; Infant; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Tuberculosis, Meningeal | 1990 |
[Treatment of tuberculosis. Drug combinations, therapeutic problems and results in a 10-year case load].
Topics: Antitubercular Agents; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Isoniazid; Male; Pyrazinamide; Recurrence; Rifampin; Tuberculosis, Pulmonary | 1990 |
Cerebellar syndrome caused by isoniazid.
Topics: Aged; Cerebellar Diseases; Female; Humans; Isoniazid; Kidney Failure, Chronic; Pyrazinamide; Pyridoxine; Renal Dialysis; Tuberculosis | 1990 |
Drug combinations and the bioavailability of rifampicin.
Topics: Antitubercular Agents; Biological Availability; Drug Combinations; Humans; Isoniazid; Pyrazinamide; Rifampin; Tuberculosis | 1990 |
Tuberculosis control and the AIDS epidemic in developing countries.
Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Developing Countries; Diagnosis, Differential; Disease Outbreaks; Drug Therapy, Combination; Humans; Isoniazid; Pyrazinamide; Rifampin; Tuberculosis | 1990 |
[Clinico-pharmacokinetic interactions of rifampicin, pyrazinamide and isoniazide].
Topics: Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Humans; Infusions, Intravenous; Isoniazid; Metabolic Clearance Rate; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 1990 |
Miliary tuberculosis: rapid diagnosis, hematologic abnormalities, and outcome in 109 treated adults.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Confidence Intervals; Female; Follow-Up Studies; Humans; Isoniazid; Male; Middle Aged; Prognosis; Pyrazinamide; Radiography; Regression Analysis; Retrospective Studies; Rifampin; Survival Rate; Time Factors; Tuberculosis, Miliary | 1990 |
Influence of initial drug resistance on the response to short-course chemotherapy of pulmonary tuberculosis.
Topics: Antitubercular Agents; Drug Evaluation; Drug Resistance, Microbial; Ethambutol; Humans; Isoniazid; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Streptomycin; Thioacetazone; Tuberculosis, Pulmonary | 1986 |
180 doses in 26 weeks vs 56 doses in 24 weeks of chemotherapy in pulmonary tuberculosis: a preliminary report.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Drug Administration Schedule; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Thioacetazone; Tuberculosis, Pulmonary | 1988 |
Drug resistance of Mycobacterium tuberculosis isolated from treated patients in Pakistan.
Topics: Adolescent; Adult; Aminosalicylic Acid; Antitubercular Agents; Drug Resistance, Microbial; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Mycobacterium tuberculosis; Pakistan; Pyrazinamide; Rifampin; Sputum; Streptomycin; Thioacetazone; Tuberculosis | 1989 |
Problems of tuberculosis treatment in Thailand.
Topics: Dose-Response Relationship, Drug; Drug Combinations; Drug Evaluation; Female; Humans; Isoniazid; Male; National Health Programs; Pyrazinamide; Rifampin; Streptomycin; Thailand; Thioacetazone; Tuberculosis | 1989 |
Six months' chemotherapy for lymph node tuberculosis.
Topics: Adolescent; Adult; Drug Administration Schedule; Female; Humans; India; Isoniazid; Male; Middle Aged; Prognosis; Pyrazinamide; Retrospective Studies; Rifampin; Tuberculosis, Lymph Node; United Kingdom | 1989 |
Mycobacterium simiae as a cause of intra-abdominal disease: a case report.
Topics: Abdomen; Adult; Ascitic Fluid; Drug Therapy, Combination; Female; Humans; Isoniazid; Kanamycin; Mycobacterium; Mycobacterium Infections; Mycobacterium Infections, Nontuberculous; Nontuberculous Mycobacteria; Ofloxacin; Pyrazinamide; Rifampin | 1989 |
[Tuberculosis in children in 1989].
Topics: Acquired Immunodeficiency Syndrome; Adolescent; Age Factors; Anti-Bacterial Agents; BCG Vaccine; Child; Child, Preschool; Drug Therapy, Combination; Humans; Infant; Infant, Newborn; Isoniazid; Pyrazinamide; Rifampin; Tuberculosis | 1989 |
[Tuberculous ulcer of the tongue: clinical case].
Topics: Adult; Female; Humans; Isoniazid; Pyrazinamide; Rifampin; Tongue Diseases; Tuberculosis; Tuberculosis, Oral; Tuberculosis, Pulmonary; Ulcer | 1989 |
[Experience with intensive short-term chemotherapy of patients with recently diagnosed destructive pulmonary tuberculosis].
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifamycins; Streptomycin; Time Factors; Tuberculosis, Pulmonary | 1989 |
Importance of rifampicin in combined daily/intermittent chemotherapy for tuberculosis.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Dapsone; Drug Combinations; Drug Evaluation; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Microbial Sensitivity Tests; Middle Aged; Prothionamide; Pyrazinamide; Rifampin; Sputum; Tuberculosis, Pulmonary | 1989 |
[Hepatotoxic effect of a combination of pyrazinamide with isoniazid and rifampicin].
Topics: Animals; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Drug Synergism; Isoniazid; Liver; Male; Pyrazinamide; Rats; Rifampin | 1989 |
Human bioavailability studies.
Topics: Biological Availability; Drug Combinations; Humans; Isoniazid; Pyrazinamide; Rifampin | 1989 |
Internuclear ophthalmoplegia in tuberculous meningitis.
Topics: Adult; Brain Stem; Cerebral Infarction; Dexamethasone; Drug Therapy, Combination; Endarteritis; Humans; Isoniazid; Male; Middle Aged; Ophthalmoplegia; Prognosis; Pyrazinamide; Rifampin; Tuberculosis, Meningeal | 1989 |
[Recommendations for the therapy of tuberculosis. (Position: December, 1988)].
Topics: Antitubercular Agents; Ethambutol; Humans; Isoniazid; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis | 1989 |
Activity and penetration of antituberculosis drugs in mouse peritoneal macrophages infected with Mycobacterium microti OV254.
Topics: Animals; Antitubercular Agents; Culture Media; Hydrogen-Ion Concentration; In Vitro Techniques; Isoniazid; Macrophages; Mice; Mice, Inbred BALB C; Mycobacterium Infections; Pyrazinamide; Rifampin; Streptomycin; Time Factors | 1989 |
Experimental short-course preventive therapy of tuberculosis with rifampin and pyrazinamide.
Topics: Animals; BCG Vaccine; Colony Count, Microbial; Drug Administration Schedule; Drug Therapy, Combination; Isoniazid; Mice; Pyrazinamide; Rifampin; Spleen; Time Factors; Tuberculosis | 1989 |
Antimycobacterial drugs and the production of reactive oxidants by polymorphonuclear leucocytes in vitro.
Topics: Antitubercular Agents; Ethambutol; In Vitro Techniques; Isoniazid; Luminescent Measurements; Neutrophils; Oxidation-Reduction; Peroxidase; Pyrazinamide; Rifampin; Streptomycin | 1988 |
Hepatic toxicity during chemotherapy for severe tuberculosis meningitis.
Topics: Alanine Transaminase; Antitubercular Agents; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Child, Preschool; Drug Combinations; Ethionamide; gamma-Glutamyltransferase; Humans; Infant; Isoniazid; Liver Diseases; Pyrazinamide; Rifampin; Tuberculosis, Meningeal | 1987 |
[Routine use of 6-month antitubercular treatment in 300 patients].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antitubercular Agents; Drug Therapy, Combination; Drug Tolerance; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Patient Compliance; Pyrazinamide; Retrospective Studies; Rifampin; Time Factors; Tuberculosis | 1986 |
[Drug-induced pellagroid erythema. A case of pellagroid erythema caused by isoniazide].
Topics: Antineoplastic Agents; Erythema; Ethionamide; Female; Humans; Isoniazid; Middle Aged; Monoamine Oxidase Inhibitors; Niacinamide; Pellagra; Pyrazinamide; Pyridoxine; Skin | 1987 |
A rapid method for the evaluation of new antituberculous agents.
Topics: Antitubercular Agents; Carbon Dioxide; Ethambutol; Guanidines; Isoniazid; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Scintillation Counting; Streptomycin; Succinimides; Thiazoles; Time Factors | 1987 |
[Fully supervised ambulatory short-course chemotherapy with an intermittent regimen for newly diagnosed smear-positive pulmonary tuberculosis].
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Isoniazid; Male; Middle Aged; Mycobacterium tuberculosis; Outpatient Clinics, Hospital; Pyrazinamide; Rifampin; Sputum; Tuberculosis, Pulmonary | 1987 |
[Long-term results of short-course chemotherapy in pulmonary tuberculosis (final report). The third study: comparative study of two regimens, 6RHZ and -6RHS (treatment was continued for 6 months after negative conversion of sputum by culture)].
Topics: Adult; Aged; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Isoniazid; Male; Middle Aged; Mycobacterium tuberculosis; Pyrazinamide; Recurrence; Rifampin; Sputum; Streptomycin; Tuberculosis, Pulmonary | 1988 |
Primary antituberculosis drug resistance and acquired rifampicin resistance in Gujarat, India.
Topics: Antitubercular Agents; Drug Resistance, Microbial; Humans; India; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Pulmonary | 1988 |
Airway obstruction secondary to tuberculosis lymph node erosion into the trachea: drainage via bronchoscopy.
Topics: Airway Obstruction; Bronchoscopy; Drainage; Female; Humans; Infant; Isoniazid; Pyrazinamide; Radiography; Rifampin; Tracheal Diseases; Tuberculosis, Lymph Node; Tuberculosis, Pulmonary | 1988 |
In vitro activity of ciprofloxacin in combination with standard antituberculous drugs against mycobacterium tuberculosis.
Topics: Antitubercular Agents; Ciprofloxacin; Ethambutol; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Streptomycin | 1988 |
[New and future drugs in pulmonary tuberculosis].
Topics: Antitubercular Agents; Drug Resistance, Microbial; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 1988 |
Management and outcome of pulmonary tuberculosis in adults notified in England and Wales in 1983. Medical Research Council Tuberculosis and Chest Diseases Unit.
Topics: Adolescent; Adult; Antitubercular Agents; Bangladesh; Drug Administration Schedule; England; Ethambutol; Female; Follow-Up Studies; Hospitalization; Humans; India; Isoniazid; Male; Pakistan; Patient Acceptance of Health Care; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary; Wales | 1988 |
Comparative bioavailability of isoniazid, rifampin, and pyrazinamide administered in free combination and in a fixed triple formulation designed for daily use in antituberculosis chemotherapy. I. Single-dose study.
Topics: Adult; Antitubercular Agents; Biological Availability; Drug Administration Schedule; Drug Combinations; Female; Humans; Isoniazid; Male; Middle Aged; Osmolar Concentration; Pyrazinamide; Rifampin | 1988 |
Comparative bioavailability of isoniazid, rifampin, and pyrazinamide administered in free combination and in a fixed triple formulation designed for daily use in antituberculosis chemotherapy. II. Two-month, daily administration study.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Biological Availability; Drug Administration Schedule; Drug Combinations; Female; Humans; Isoniazid; Male; Middle Aged; Osmolar Concentration; Pyrazinamide; Rifampin | 1988 |
A retrospective comparison of two drug regimens RHE2/RH10 and RHZ2/RH10 in the treatment of tuberculous mediastinal lymphadenopathy.
Topics: Adolescent; Adult; Aged; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Mediastinal Diseases; Middle Aged; Pyrazinamide; Radiography; Rifampin; Time Factors; Tuberculosis, Lymph Node | 1988 |
[A crossed pharmacokinetic assay of two presentations of HRZ: one with combined components and one with isolated components H+R+Z].
Topics: Administration, Oral; Adult; Drug Combinations; Female; Humans; Isoniazid; Male; Pyrazinamide; Rifampin | 1988 |
[Isoniazid and pyrazinamide: in vitro effect on polymorphonuclear leukocytes].
Topics: Candida albicans; Cell Adhesion; Cell Movement; Humans; In Vitro Techniques; Isoniazid; Neutrophils; Phagocytosis; Pyrazinamide | 1987 |
Drugs for tuberculosis.
Topics: Adult; Aged; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Child; Drug Administration Schedule; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Middle Aged; Pyrazinamide; Rifampin; Tuberculosis | 1988 |
Tuberculosis presenting as laryngeal stridor in a child.
Topics: Child, Preschool; Humans; Injections, Intramuscular; Injections, Spinal; Isoniazid; Larynx; Lung; Male; Pyrazinamide; Respiratory Sounds; Rifampin; Streptomycin; Tomography, X-Ray Computed; Tuberculosis, Laryngeal; Tuberculosis, Miliary | 1988 |
Tuberculosis verrucosa cutis: clinical picture and response to short-course chemotherapy.
Topics: Adult; Humans; Isoniazid; Male; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Cutaneous | 1988 |
American Thoracic Society. Medical Section of the American Lung Association: Treatment of tuberculosis and tuberculosis infection in adults and children.
Topics: Adult; Age Factors; Blood Cell Count; Blood Urea Nitrogen; Child; Creatinine; Drug Administration Schedule; Drug Resistance, Microbial; Ethambutol; Female; Humans; Isoniazid; Lactation; Liver; Mycobacterium bovis; Pregnancy; Pyrazinamide; Rifampin; Sputum; Streptomycin; Time Factors; Tuberculin; Tuberculosis | 1986 |
[Lupoid syndrome in "BCG-itis." Report of a case].
Topics: Adult; BCG Vaccine; Female; Humans; Isoniazid; Lupus Vulgaris; Prednisolone; Pyrazinamide; Rifampin | 1986 |
Pott's paraplegia.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Female; Humans; Infant; Isoniazid; Male; Middle Aged; Paraplegia; Pyrazinamide; Rifampin; Spinal Canal; Spinal Fusion; Streptomycin; Tuberculosis, Spinal | 1987 |
New approach to treatment of pulmonary and extrapulmonary tuberculosis. Possible ramifications of cutaneous mycobacterial infections.
Topics: Ethambutol; Humans; Isoniazid; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Cutaneous; Tuberculosis, Pulmonary | 1987 |
From the Centers for Disease Control. Conference on new approaches for tuberculosis preventive therapy.
Topics: Antitubercular Agents; Humans; Isoniazid; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 1987 |
[Chemotherapy of pulmonary tuberculosis. Sputum culture conversion in 8 weeks in 84% of patients].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antitubercular Agents; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Isoniazid; Lung; Male; Middle Aged; Pyrazinamide; Radiography; Rifampin; Sputum; Time Factors; Tuberculosis, Pulmonary | 1987 |
Treatment of tuberculous meningitis: role of short-course chemotherapy.
Topics: Adolescent; Adult; Aged; Drug Administration Schedule; Drug Therapy, Combination; Humans; Isoniazid; Middle Aged; Prospective Studies; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Meningeal | 1987 |
Short-course antituberculous chemotherapy for pulmonary and pleural disease: 5 years' experience in clinical practice.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antitubercular Agents; Drug Administration Schedule; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Pyridoxine; Rifampin; Streptomycin; Tuberculosis, Pleural; Tuberculosis, Pulmonary | 1987 |
Antituberculous agents.
Topics: Antitubercular Agents; Ethambutol; Humans; Isoniazid; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis | 1987 |
[Studies of short-term chemotherapy of tuberculosis. III. Early and late results of 6 months' treatment of tuberculosis. Analysis of failures and recurrences during 1-5 years' observation].
Topics: Adolescent; Adult; Aged; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Isoniazid; Male; Middle Aged; Patient Dropouts; Pyrazinamide; Recurrence; Rifampin; Time Factors; Tuberculosis, Pulmonary | 1986 |
The bioavailability of isoniazid, rifampin, and pyrazinamide in two commercially available combined formulations designed for use in the short-course treatment of tuberculosis.
Topics: Acetylation; Adolescent; Adult; Biological Availability; Drug Combinations; Humans; Isoniazid; Middle Aged; Osmolar Concentration; Phenotype; Pyrazinamide; Rifampin; Time Factors; Tuberculosis | 1986 |
[Results of a therapeutic trial comparing a 6-month regimen to a 12-month regimen in the treatment of pulmonary tuberculosis in the Algerian Sahara. Final report: results 3 years after the onset of treatment].
Topics: Adult; Algeria; Antitubercular Agents; Drug Administration Schedule; Drug Resistance, Microbial; Ethambutol; Female; Follow-Up Studies; Humans; Isoniazid; Male; Pyrazinamide; Recurrence; Rifampin; Streptomycin; Transients and Migrants; Tuberculosis, Pulmonary | 1986 |
Short-course tuberculosis therapy--a new combination product.
Topics: Drug Combinations; Humans; Isoniazid; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 1986 |
Pyrazinamide in treatment of tuberculous meningitis.
Topics: Drug Therapy, Combination; Humans; Isoniazid; Pyrazinamide; Rifampin; Tuberculosis, Meningeal | 1986 |
[Tuberculostatics-induced systemic lupus erythematosus].
Topics: Antitubercular Agents; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Lupus Erythematosus, Systemic; Middle Aged; Prothionamide; Pyrazinamide; Streptomycin; Tuberculosis, Pulmonary | 1986 |
Hepatic toxicity in South Indian patients during treatment of tuberculosis with short-course regimens containing isoniazid, rifampicin and pyrazinamide.
Topics: Adolescent; Adult; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Humans; Infant; Isoniazid; Jaundice; Liver; Pyrazinamide; Rifampin; Tuberculosis; Tuberculosis, Meningeal; Tuberculosis, Pulmonary; Tuberculosis, Spinal | 1986 |
Short-course chemotherapy of pulmonary tuberculosis: a new approach to drug dosage in the initial intensive phase.
Topics: Antitubercular Agents; Body Weight; Drug Therapy, Combination; Humans; Isoniazid; Pyrazinamide; Rifampin; Tablets; Time Factors; Tuberculosis, Pulmonary | 1986 |
Package inserts for antituberculosis drugs and tuberculins.
Topics: Antitubercular Agents; Child; Child, Preschool; Contraceptives, Oral; Drug Interactions; Drug Labeling; Drug Synergism; Humans; Isoniazid; Mycobacterium Infections; Outpatients; Pyrazinamide; Rifampin; Tuberculin; United States; United States Food and Drug Administration | 1985 |
Safety of thrice-weekly rifampicin for tuberculosis in South-East Asian refugees.
Topics: Adolescent; Adult; Aged; Asia, Southeastern; Australia; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Drug Administration Schedule; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Middle Aged; Prospective Studies; Pyrazinamide; Refugees; Rifampin; Tuberculosis, Pulmonary | 1985 |
The action of antituberculosis drugs in short-course chemotherapy.
Topics: Antitubercular Agents; Drug Resistance, Microbial; Ethambutol; Humans; Isoniazid; Models, Biological; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Sterilization; Streptomycin; Time Factors; Tuberculosis, Pulmonary | 1985 |
[The latest topics concerning pyrazinamide].
Topics: Adolescent; Adult; Animals; Child; Drug Resistance, Microbial; Drug Synergism; Female; Humans; Isoniazid; Male; Mice; Middle Aged; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Tuberculosis | 1985 |
Short-course chemotherapy for extrapulmonary tuberculosis. Nine years' experience.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Drug Administration Schedule; Female; Humans; Isoniazid; Male; Middle Aged; Prospective Studies; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis | 1986 |
Pharmacokinetic studies on antituberculosis regimens in humans. I. Absorption and metabolism of the compounds used in the initial intensive phase of the short-course regimens: single administration study.
Topics: Absorption; Antitubercular Agents; Humans; Isoniazid; Kinetics; Male; Pyrazinamide; Rifampin; Streptomycin | 1985 |
Six-month chemotherapy for urogenital tuberculosis.
Topics: Adult; Aged; Drug Therapy, Combination; Female; Humans; Isoniazid; Middle Aged; Pyrazinamide; Radiography; Rifampin; Tuberculosis, Urogenital | 1985 |
Tuberculosis in an Indochinese refugee camp: epidemiology, management and therapeutic results.
Topics: Adolescent; Adult; Antitubercular Agents; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Infant; Isoniazid; Middle Aged; Patient Compliance; Pregnancy; Pyrazinamide; Refugees; Rifampin; Streptomycin; Thailand; Tuberculosis; Tuberculosis, Lymph Node; Tuberculosis, Pulmonary | 1985 |
Field trial of short course chemotherapy for pulmonary tuberculosis: results at 30 months.
Topics: Adolescent; Adult; Drug Therapy, Combination; Female; Humans; Isoniazid; Male; Pyrazinamide; Rifampin; Thailand; Time Factors; Tuberculosis, Pulmonary | 1985 |
Ultrashort-course chemotherapy for culture-negative pulmonary tuberculosis--a qualified success.
Topics: Antitubercular Agents; Drug Therapy, Combination; Ethambutol; Follow-Up Studies; Humans; Isoniazid; Male; Pyrazinamide; Random Allocation; Rifampin; Time Factors; Tuberculosis, Pulmonary | 1985 |
Failure of a prothionamide-containing oral antituberculosis regimen.
Topics: Administration, Oral; Antitubercular Agents; Dapsone; Drug Combinations; Drug Therapy, Combination; Humans; Isoniazid; Isonicotinic Acids; Male; Patient Compliance; Prothionamide; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 1985 |
Tuberculosis of the knee.
Topics: Adolescent; Adult; Child; Combined Modality Therapy; Female; Follow-Up Studies; Humans; Immobilization; Isoniazid; Knee Joint; Male; Pyrazinamide; Radiography; Rifampin; Streptomycin; Tuberculosis, Osteoarticular | 1985 |
Adult tuberculous meningitis: comparative study of different chemotherapeutic regimens.
Topics: Adolescent; Adult; Aminosalicylic Acid; Antitubercular Agents; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Prospective Studies; Pyrazinamide; Random Allocation; Rifampin; Streptomycin; Tuberculosis, Meningeal | 1985 |
The first clinical experiences with ethambutol in chronic pulmonary tuberculosis and basilar meningitis.
Topics: Adult; Aminosalicylic Acids; Capreomycin; Chronic Disease; Cycloserine; Drug Combinations; Drug Resistance, Microbial; Ethambutol; Ethionamide; Female; Humans; Isoniazid; Kanamycin; Male; Meningitis; Middle Aged; Pyrazinamide; Radiography; Streptomycin; Tuberculosis, Pulmonary; Viomycin | 1970 |
Clinical experience with ethambutol.
Topics: Aminosalicylic Acids; Blood Chemical Analysis; Capreomycin; Drug Combinations; Drug Hypersensitivity; Drug Resistance, Microbial; Ethambutol; Ethionamide; Gentamicins; Humans; Isoniazid; Kanamycin; Pyrazinamide; Streptomycin; Tuberculosis, Pulmonary; Viomycin | 1970 |
Shorter chemotherapy in tuberculosis.
Topics: Developing Countries; Drug Combinations; Economics; Humans; Isoniazid; Pyrazinamide; Rifampin; Streptomycin; Thioacetazone; Time Factors; Tuberculosis, Pulmonary | 1972 |
[Characteristics of drug-induced hepatitis in patients with tuberculosis].
Topics: Aminosalicylic Acids; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Ethionamide; Humans; Isoniazid; Liver; Pyrazinamide; Streptomycin; Thioacetazone; Tuberculosis | 1972 |
Technical and bacteriological aspects of a continuous survey of drug resistance in tuberculosis in South Africa.
Topics: Aminosalicylic Acids; Computers; Cycloserine; Diffusion; Drug Resistance, Microbial; Ethionamide; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrazinamide; South Africa; Sputum; Streptomycin; Thioacetazone; Tuberculosis, Pulmonary | 1972 |
[Allergy to antitubercular agents; with special reference to new drugs].
Topics: Adult; Aged; Agranulocytosis; Anaphylaxis; Antitubercular Agents; Capreomycin; Cycloserine; Drug Hypersensitivity; Ethambutol; Ethionamide; Female; Humans; Isoniazid; Kanamycin; Pyrazinamide; Rifampin; Thrombocytopenia; Viomycin | 1973 |
Pyrazinamide and other drugs in tuberculous meningitis.
Topics: Adult; Blood-Brain Barrier; Humans; Isoniazid; Male; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Meningeal | 1973 |
[Proceedings: Ambulatory chemotherapy of tuberculosis in Finland (organization)].
Topics: Ambulatory Care; Aminosalicylic Acids; Antitubercular Agents; Capreomycin; Ethambutol; Ethionamide; Finland; Humans; Isoniazid; Patient Dropouts; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis; Tuberculosis, Pulmonary | 1973 |
Short-course treatment in pulmonary tuberculosis.
Topics: Adolescent; Adult; Africa, Eastern; Antitubercular Agents; Humans; Isoniazid; Mycobacterium tuberculosis; Pyrazinamide; Recurrence; Rifampin; Sputum; Streptomycin; Thioacetazone; Time Factors; Tuberculosis, Pulmonary | 1973 |
[Drug therapy of tuberculosis].
Topics: Amides; Aminosalicylic Acids; Antitubercular Agents; Capreomycin; Drug Therapy, Combination; Ethambutol; Ethionamide; Humans; Isoniazid; Isonicotinic Acids; Kanamycin; Phenylthiourea; Pyrazinamide; Rifampin; Streptomycin; Tetracycline; Thiosemicarbazones; Tuberculosis; Viomycin | 1974 |
Primary cutaneous inoculation drug-resistant tuberculosis.
Topics: Capreomycin; Drug Resistance, Microbial; Ethambutol; Female; Humans; Isoniazid; Laboratory Infection; Middle Aged; Mycobacterium tuberculosis; Needles; Punctures; Pyrazinamide; Streptomycin; Thumb; Tuberculin Test; Tuberculosis, Cutaneous | 1974 |
Management of drug failure cases.
Topics: Adult; Aged; Aminosalicylic Acids; Antitubercular Agents; Collapse Therapy; Congresses as Topic; Cycloserine; Drug Resistance, Microbial; Ethambutol; Ethionamide; Female; Humans; India; Isoniazid; Male; Microbial Sensitivity Tests; Middle Aged; Prognosis; Pyrazinamide; Tuberculosis, Pulmonary | 1972 |
Sodium nitroprusside test for the detection of isoniazid and acetylisoniazid in urine.
Topics: Aminosalicylic Acids; Cycloserine; Ethionamide; Ferrocyanides; Humans; Indicators and Reagents; Isoniazid; Pyrazinamide; Streptomycin; Thioacetazone | 1967 |
In vitro and in vivo studies to assess the suitability of antituberculous drugs for use in intermittent chemotherapy regimens.
Topics: Animals; Antitubercular Agents; Cycloserine; Ethambutol; Ethionamide; Guinea Pigs; In Vitro Techniques; Isoniazid; Mycobacterium tuberculosis; Phenylthiourea; Pyrazinamide; Streptomycin; Thioacetazone; Time Factors; Tuberculosis | 1968 |
Tuberculosis Chemotherapy Centre, Madras.
Topics: Antitubercular Agents; Cycloserine; Diet Therapy; Drug Resistance, Microbial; Ethionamide; Home Care Services; Humans; India; Isoniazid; Pyrazinamide; Streptomycin; Thioacetazone; Tuberculosis, Pulmonary | 1968 |
Drugs for tuberculosis.
Topics: Aminosalicylic Acids; Costs and Cost Analysis; Cycloserine; Drug Synergism; Ethambutol; Ethionamide; Humans; Isoniazid; Kanamycin; Pyrazinamide; Streptomycin; Thioacetazone; Tuberculosis; Viomycin | 1968 |
In vitro and in vivo studies to assess the suitability of anti-tuberculous drugs for use in intermittent chemotherapy regimens.
Topics: Animals; Antitubercular Agents; Cycloserine; Ethambutol; Ethionamide; Guinea Pigs; In Vitro Techniques; Isoniazid; Methods; Phenylthiourea; Pyrazinamide; Streptomycin; Thioacetazone; Tuberculosis | 1968 |
New drugs against tuberculosis.
Topics: Animals; Antitubercular Agents; Cortisone; Isoniazid; Mice; Pyrazinamide; Rifampin | 1969 |
Comparison of various drug regimens in domiciliary chemotherapy.
Topics: Adolescent; Adult; Costs and Cost Analysis; Home Care Services; Humans; Isoniazid; Middle Aged; Mycobacterium tuberculosis; Pyrazinamide; Sputum; Streptomycin; Thioacetazone; Time Factors; Tuberculosis, Pulmonary | 1970 |
[Pulmonary tuberculosis resistant to streptomycin and isoniazid and treated wtih a combination of ethionamide, pyrazinamide, and cycloserine (200 cases)].
Topics: Adolescent; Adult; Age Factors; Aged; Aminosalicylic Acids; Child; Cycloserine; Drug Resistance, Microbial; Ethionamide; Female; Humans; Isoniazid; Male; Middle Aged; Morocco; Mycobacterium tuberculosis; Pyrazinamide; Recurrence; Residence Characteristics; Rifampin; Sex Factors; Streptomycin; Time Factors; Tuberculosis, Pulmonary | 1973 |
The effect of radiation on microbiologic characteristics of M tuberculosis.
Topics: Aminosalicylic Acids; Antitubercular Agents; Cell Survival; Chromosomes, Bacterial; Cycloserine; Dose-Response Relationship, Radiation; Drug Resistance, Microbial; Ethambutol; Ethionamide; Freezing; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Preservation, Biological; Pyrazinamide; Radiation Genetics; Rifampin; Streptomycin | 1974 |
[Algodystrophy associated with antitubercular chemotherapy: 22 cases].
Topics: Adult; Antitubercular Agents; Cycloserine; Ethambutol; Ethionamide; Female; Humans; Isoniazid; Male; Niacinamide; Pyrazinamide; Reflex Sympathetic Dystrophy; Rifampin; Tuberculosis; Vitamin B Deficiency | 1969 |
[Results of outpatient treatment of tuberculous patients in a rural area of the Moldavian SSR].
Topics: Adolescent; Adult; Ambulatory Care; Aminosalicylic Acids; Antitubercular Agents; Cycloserine; Ethionamide; Female; Humans; Isoniazid; Kanamycin; Male; Middle Aged; Moldova; Pyrazinamide; Rural Health; Streptomycin; Thiosemicarbazones; Tuberculosis | 1974 |
Bacteriology of tuberculosis with special reference to kanamycin and related drugs.
Topics: Aminosalicylic Acids; Antitubercular Agents; Cycloserine; Drug Resistance, Microbial; Ethionamide; Humans; Isoniazid; Kanamycin; Pyrazinamide; Streptomycin; Tuberculosis; Viomycin | 1966 |
[Therapy of pulmonary tuberculosis in its current aspects].
Topics: Aminosalicylic Acids; Anti-Bacterial Agents; Antitubercular Agents; Cycloserine; Ethionamide; Humans; Isoniazid; Kanamycin; Phenylthiourea; Pyrazinamide; Streptomycin; Tuberculosis, Pulmonary; Viomycin | 1965 |
The results of treatment in patients with cultures resistant to streptomycin, isoniazid and PAS: a five-year follow-up.
Topics: Aminosalicylic Acids; Cycloserine; Drug Resistance, Microbial; Ethionamide; Follow-Up Studies; Humans; Isoniazid; Mycobacterium tuberculosis; Pneumonectomy; Pyrazinamide; Streptomycin; Tuberculosis, Pulmonary; Viomycin | 1967 |
The susceptibility of mycobacteria to rifamide and rifampicin.
Topics: Aminosalicylic Acids; Anti-Bacterial Agents; Antitubercular Agents; Cycloserine; Drug Resistance, Microbial; Ethionamide; Humans; Injections, Intravenous; Isoniazid; Kanamycin; Mycobacterium; Mycobacterium bovis; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Streptomycin; Thiosemicarbazones; Viomycin | 1967 |
Treatment of pulmonary tuberculosis.
Topics: Aminosalicylic Acids; Drug Resistance, Microbial; Humans; Isoniazid; Kanamycin; Pyrazinamide; Streptomycin; Tuberculosis, Pulmonary; Viomycin | 1967 |
Studies on the mode of action of isoniazid on mycobacteria.
Topics: Aminosalicylic Acids; Drug Resistance, Microbial; Hot Temperature; Isoniazid; Mycobacterium tuberculosis; N-Glycosyl Hydrolases; NAD; Pyrazinamide; Streptomycin | 1967 |
Experimental chemotherapy of tuberculosis.
Topics: Adrenocorticotropic Hormone; Animals; Antitubercular Agents; Bacteriological Techniques; Cortisone; Ethionamide; Guinea Pigs; Humans; Isoniazid; Lung; Male; Methods; Mice; Middle Aged; Pyrazinamide; Spleen; Streptomycin; Sulfones; Time Factors | 1968 |
[The drug treatment of renal tuberculosis].
Topics: Adrenal Cortex Hormones; Aminosalicylic Acids; Antitubercular Agents; Cycloserine; Ethionamide; Humans; Isoniazid; Kanamycin; Phenylthiourea; Pyrazinamide; Streptomycin; Tuberculosis, Renal; Ureteral Obstruction; Viomycin | 1967 |
A continuing study of patients with "open negative" status at Battey State Hospital.
Topics: Adolescent; Adult; Aged; Aminosalicylic Acids; Child; Cycloserine; Female; Follow-Up Studies; Georgia; Humans; Isoniazid; Male; Middle Aged; Mycobacterium tuberculosis; Pyrazinamide; Sputum; Streptomycin; Tuberculosis, Pulmonary; Viomycin | 1968 |
Ethambytol in the retreatment of pulmonary tuberculosis. United States Public Health Service cooperative trial.
Topics: Cycloserine; Drug Resistance, Microbial; Ethambutol; Ethionamide; Humans; Isoniazid; Kanamycin; Pyrazinamide; Thiosemicarbazones; Tuberculosis, Pulmonary; United States; United States Public Health Service; Viomycin | 1968 |
The problem of the chronic excretor of tubercle bacilli.
Topics: Adult; Age Factors; Aged; Aminosalicylic Acids; Chronic Disease; Cycloserine; Czechoslovakia; Drug Resistance, Microbial; Ethionamide; Female; Hospitalization; Humans; Isoniazid; Male; Methods; Middle Aged; Mycobacterium tuberculosis; Public Health; Pyrazinamide; Sex Factors; Sputum; Streptomycin; Time Factors; Tuberculosis, Pulmonary; Viomycin | 1968 |
[Drug sensitivity of the so-called atypical mycobacteria].
Topics: Aminosalicylic Acids; Antitubercular Agents; Cycloserine; Drug Resistance, Microbial; Ethambutol; Ethionamide; In Vitro Techniques; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Morpholines; Mycobacterium; Pyrazinamide; Pyrazines; Rifampin; Streptomycin; Viomycin | 1968 |
Ethambutol in the treatment of 26 patients with chronic active pulmonary tuberculosis.
Topics: Chronic Disease; Cycloserine; Drug Resistance, Microbial; Ethambutol; Humans; Isoniazid; Kanamycin; Pyrazinamide; Tuberculosis, Pulmonary; Viomycin | 1969 |
Chemotherapy of tuberculosis.
Topics: Aminosalicylic Acids; Antitubercular Agents; Cycloserine; Ethambutol; Ethionamide; Humans; Isoniazid; Kanamycin; Pyrazinamide; Streptomycin; Tuberculosis, Pulmonary; Viomycin | 1970 |
[Kanamycin and florimycin in the clinical course of pulmonary tuberculosis].
Topics: Adolescent; Adult; Albuminuria; Aminosalicylic Acids; Antitubercular Agents; Chronic Disease; Cycloserine; Depression, Chemical; Drug Resistance, Microbial; Eosinophilia; Ethionamide; Headache; Hearing Disorders; Hematuria; Humans; Isoniazid; Kanamycin; Lung Diseases; Middle Aged; Mycobacterium tuberculosis; Pruritus; Pyrazinamide; Respiratory Therapy; Tachycardia; Thiosemicarbazones; Time Factors; Tinnitus; Tuberculosis, Pulmonary; Vertigo; Vestibule, Labyrinth; Viomycin | 1971 |
Treatment of drug-resistant tuberculosis.
Topics: Aminosalicylic Acids; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Cycloserine; Drug Eruptions; Drug Hypersensitivity; Drug Resistance, Microbial; Drug Synergism; Ethambutol; Ethionamide; Female; Gastrointestinal Diseases; Humans; Hypothyroidism; Isoniazid; Kanamycin; Male; Microbial Sensitivity Tests; Pyrazinamide; Recurrence; Rifampin; Streptomycin; Tuberculosis, Pulmonary; Viomycin | 1971 |
[Advances and principles in tuberculostatic therapy].
Topics: Adult; Aminosalicylic Acids; Antitubercular Agents; Cycloserine; Drug Resistance, Microbial; Ethambutol; Ethionamide; Female; Humans; Isoniazid; Kanamycin; Male; Microbial Sensitivity Tests; Middle Aged; Phenylthiourea; Pyrazinamide; Rifampin; Streptomycin; Thiosemicarbazones; Tuberculosis; Viomycin | 1971 |
[Duration of the after-control of the tuberculous patients following the termination of the treatment].
Topics: Adolescent; Adult; Aminosalicylic Acids; Antitubercular Agents; Cycloserine; Ethambutol; Ethionamide; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Recurrence; Rifampin; Streptomycin; Thiosemicarbazones; Time Factors; Tuberculosis, Pulmonary; Viomycin | 1972 |
Effect of pyrazinamide on nicotinamide adenine dinucleotide glycohydrolase of tuberculous host.
Topics: Animals; Drug Resistance, Microbial; Isoniazid; Liver; Male; Mice; Mycobacterium Infections; Mycobacterium tuberculosis; N-Glycosyl Hydrolases; NAD; Niacinamide; Pyrazinamide | 1973 |
Treatment of tuberculosis today in Nebraska.
Topics: Aminosalicylic Acids; Antitubercular Agents; Cycloserine; Drug Hypersensitivity; Ethambutol; Ethionamide; Humans; Isoniazid; Kanamycin; Pyrazinamide; Pyridoxine; Rifampin; Sputum; Streptomycin; Tuberculosis; Viomycin | 1973 |
New antituberculosis drugs and concepts of prophylaxis.
Topics: Aminosalicylic Acids; Antitubercular Agents; Arthritis; Chemical and Drug Induced Liver Injury; Child; Cycloserine; Drug Hypersensitivity; Drug Resistance, Microbial; Ethambutol; Ethionamide; Humans; Isoniazid; Kanamycin; Liver; Lupus Vulgaris; Male; Middle Aged; Pyrazinamide; Rifampin; Streptomycin; Tuberculin Test; Tuberculosis; Viomycin | 1974 |
Intermittent chemotherapy for adults with tuberculosis.
Topics: Administration, Oral; Adult; Drug Resistance, Microbial; Ethambutol; Humans; Injections, Intramuscular; Isoniazid; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis | 1974 |
[Identification of human chromosomes by chromomerization in vitro].
Topics: Aminosalicylic Acids; Antitubercular Agents; Cells, Cultured; Chromosome Aberrations; Chromosomes; Cytogenetics; Heterochromatin; Humans; Isoniazid; Lymphocytes; Nucleic Acid Denaturation; Pyrazinamide | 1972 |
Shorter treatment.
Topics: Animals; Drug Combinations; Humans; Isoniazid; Pyrazinamide; Recurrence; Rifampin; Time Factors; Tuberculosis, Pulmonary | 1972 |
Treatment of urogenital tuberculosis with terivalidin.
Topics: Adult; Aminosalicylic Acids; Anti-Infective Agents, Urinary; Antitubercular Agents; Cystoscopy; Drug Therapy, Combination; Female; Humans; Imines; Isoniazid; Kidney; Kidney Pelvis; Male; Middle Aged; Nephrectomy; Oxazoles; Prednisolone; Pyrazinamide; Pyuria; Radiography; Streptomycin; Tuberculosis, Renal; Tuberculosis, Urogenital; Ureteral Diseases | 1972 |
[Toxicity of antitubercular agents for the liver].
Topics: Aminosalicylic Acids; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Cycloserine; Ethambutol; Ethionamide; Humans; Isoniazid; Pyrazinamide; Rifampin; Streptomycin | 1973 |
Human growth hormone therapy in hypopituitarism due to tuberculous meningitis.
Topics: Adolescent; Aminosalicylic Acids; Blood Glucose; Body Height; Calcinosis; Child; Child, Preschool; Diabetes Insipidus; Female; Growth Hormone; Hemiplegia; Humans; Hypopituitarism; Isoniazid; Obesity; Prednisone; Pyrazinamide; Streptomycin; Tuberculosis, Meningeal; Vasopressins | 1973 |
Transfer factor therapy in a patient with progressive primary tuberculosis.
Topics: Adult; Aminosalicylic Acids; Anemia, Aplastic; Cell Migration Inhibition; Ethambutol; Female; Humans; Immunity, Cellular; Immunity, Maternally-Acquired; Isoniazid; Lectins; Lymphocytes; Macrophages; Pyrazinamide; Radiography; Rifampin; Splenectomy; Streptodornase and Streptokinase; Streptomycin; Thymidine; Tritium; Tuberculin Test; Tuberculosis, Pulmonary | 1973 |
Successive manifestations of tuberculosis in a recalcitrant patient.
Topics: Adult; Aminosalicylic Acids; Communicable Disease Control; Hospitalization; Humans; Isoniazid; Male; Patient Dropouts; Pleural Effusion; Pyrazinamide; Radiography; Recurrence; Streptomycin; Tuberculosis, Miliary; Tuberculosis, Pulmonary | 1973 |
[Statement on tuberculosis treatment].
Topics: Aminosalicylic Acids; Antitubercular Agents; Drug Resistance, Microbial; Drug Therapy, Combination; Dyspepsia; Ethambutol; Ethionamide; Humans; Isoniazid; Pyrazinamide; Rifampin; Streptomycin; Thiosemicarbazones | 1973 |
Hyperuricemia induced by ethambutol.
Topics: Allopurinol; Creatinine; Diuretics; Ethambutol; Ethanol; Gout; Humans; Isoniazid; Lactates; Pyrazinamide; Pyridoxine; Salicylates; Stimulation, Chemical; Streptomycin; Time Factors; Tuberculosis; Uric Acid | 1974 |
Three patients with intracranial tuberculomas with unusual features.
Topics: Adolescent; Aminosalicylic Acids; Brain Diseases; Dexamethasone; Diabetic Coma; Electroencephalography; Emigration and Immigration; Ethambutol; Female; Headache; Humans; Hydrocephalus; India; Isoniazid; Male; Papilledema; Pyrazinamide; Radionuclide Imaging; Rifampin; Streptomycin; Technetium; Tuberculoma; United Kingdom | 1974 |
A ten-year clinical experience with Mycobacterium kansasii.
Topics: Adolescent; Adult; Aged; Aminosalicylic Acids; Antitubercular Agents; Child; Cycloserine; Ethambutol; Ethionamide; Female; Follow-Up Studies; Humans; Isoniazid; Lung Diseases; Male; Middle Aged; Mycobacterium; Mycobacterium Infections; Pneumonectomy; Pyrazinamide; Rifampin; Sputum; Streptomycin | 1974 |
The management of drug-resistant pulmonary tuberculosis.
Topics: Aminosalicylic Acids; Antitubercular Agents; Attitude; Bacteriological Techniques; Drug Resistance, Microbial; Emotions; Ethionamide; Humans; Isoniazid; Pyrazinamide; Streptomycin; Tuberculosis, Pulmonary | 1968 |
Microbial persistence. I. The capacity of tubercle bacilli to survive sterilization in mouse tissues.
Topics: Animals; Cortisone; Cross Infection; Drug Resistance, Microbial; Isoniazid; Mice; Mycobacterium tuberculosis; Pyrazinamide; Tuberculosis, Pulmonary; Tuberculosis, Splenic | 1966 |
Microbial persistence. II. Characteristics of the sterile state of tubercle bacilli.
Topics: Animals; Drug Resistance, Microbial; Isoniazid; Mice; Mycobacterium tuberculosis; Pyrazinamide; Tuberculosis, Pulmonary; Tuberculosis, Splenic | 1966 |
Kanamycin in the therapy of pulmonary tuberculosis in the United States.
Topics: Aminosalicylic Acids; Antitubercular Agents; Cycloserine; Ethionamide; Humans; Isoniazid; Kanamycin; Mycobacterium tuberculosis; Phenylthiourea; Pyrazinamide; Streptomycin; Tuberculosis, Pulmonary; United States; Vestibulocochlear Nerve | 1966 |
Significance of intracellular medium for antimycobacterial activity of some pyrazin-2-carbonic acid derivatives.
Topics: Animals; Antitubercular Agents; Culture Media; Culture Techniques; Hydrogen-Ion Concentration; Isoniazid; Mice; Mycobacterium tuberculosis; Pyrazinamide; Pyrazines | 1966 |
Urogenital tuberculosis.
Topics: Adult; Aged; Aminosalicylic Acids; Cycloserine; Drug Resistance, Microbial; Ethionamide; Female; Humans; Hydronephrosis; Isoniazid; Male; Middle Aged; Mycobacterium tuberculosis; Nephrectomy; Pyrazinamide; Streptomycin; Tuberculosis, Urogenital; Ureteral Obstruction; Urography | 1970 |
What is drug resistance?
Topics: Drug Resistance, Microbial; Humans; Isoniazid; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Pyrazinamide; Streptomycin; Tuberculosis | 1969 |
[Restoration of drug sensitivity in Mycobacterium tuberculosis to streptomycin and isoniazid during treatment with preparations of the 1st series].
Topics: Chronic Disease; Cycloserine; Drug Resistance, Microbial; Ethionamide; Humans; Isoniazid; Mycobacterium tuberculosis; Pyrazinamide; Streptomycin; Tuberculosis, Pulmonary | 1970 |
[Internal medicine treatment of pulmonary tuberculosis].
Topics: Ambulatory Care; Aminosalicylic Acids; Anti-Bacterial Agents; Antitubercular Agents; Cycloserine; Drug Resistance, Microbial; Drug Synergism; Ethambutol; Ethionamide; Humans; Isoniazid; Long-Term Care; Prednisolone; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Pulmonary | 1970 |
[Studies on the effects of antituberculosis agents against tubercle bacilli in the resting state, using streptomycin-dependent strain (18-b). II. Studies in vivo].
Topics: Animals; Antitubercular Agents; Drug Resistance, Microbial; Ethambutol; Isoniazid; Kanamycin; Male; Mice; Mice, Inbred Strains; Mycobacterium tuberculosis; Pyrazinamide; Streptomycin; Tuberculosis | 1971 |
A comparison of regimens of ethionamide, pyrazinamide and cycloserine in re-treatment of patients with pulmonary tuberculosis.
Topics: Adolescent; Adult; Chemical and Drug Induced Liver Injury; Cycloserine; Ethionamide; Gastrointestinal Diseases; Humans; Isoniazid; Mycobacterium tuberculosis; Psychoses, Substance-Induced; Pyrazinamide; Recurrence; Tuberculosis, Pulmonary | 1969 |
Acute psychotic reaction probably caused by ethionamide.
Topics: Adult; Ethionamide; Humans; Isoniazid; Male; Prednisolone; Psychoses, Substance-Induced; Pyrazinamide; Streptomycin; Tuberculosis, Pulmonary | 1972 |
Recent developments in the treatment of infectious diseases. V. Management of tuberculosis in the community hospital.
Topics: Aminosalicylic Acids; Cross Infection; Ethambutol; Humans; Isoniazid; Pyrazinamide; Rifampin; Sanitation; Streptomycin; Tuberculosis, Pulmonary | 1971 |
[Influence of various antitubercular agents on the xylose resorption test].
Topics: Aminosalicylic Acids; Antitubercular Agents; Cycloserine; Ethionamide; Humans; Intestinal Absorption; Isoniazid; Pyrazinamide; Thiosemicarbazones; Xylose | 1971 |
Drug resistant pulmonary tuberculosis treated with ethambutol and rifampicin in North East England.
Topics: Aminosalicylic Acids; Chronic Disease; Cycloserine; Drug Resistance, Microbial; Ethambutol; Ethionamide; Humans; Isoniazid; Microbial Sensitivity Tests; Pyrazinamide; Rifampin; Sputum; Streptomycin; Tuberculosis, Pulmonary | 1971 |
The effect of pyrazinamide, rifampicin and cycloserine on the blood levels and urinary excretion of isoniazid.
Topics: Cycloserine; Humans; Isoniazid; Pyrazinamide; Rifampin; Tuberculosis | 1971 |
Genetic variations in the acetylation of isoniazid and other drugs.
Topics: Adult; Aminobenzoates; Aminosalicylic Acids; Asian People; Black People; Body Weight; Depression; Female; Genetic Variation; Humans; Isoniazid; Metabolism, Inborn Errors; Middle Aged; Pharmacogenetics; Phenotype; Polymorphism, Genetic; Pregnancy; Pyrazinamide; Streptomycin; Tuberculosis; Twins; White People | 1968 |
General survey of the clinical results of treatment of pulmonary tuberculosis with cycloserine in Turkey.
Topics: Cycloserine; Ethionamide; Humans; Isoniazid; Pyrazinamide; Tuberculosis, Pulmonary | 1970 |
Experimental studies on therapeutic effects of various combinations of antituberculosis drugs. I. Comparison of various regimens in treatment of experimental mouse tuberculosis infected with drug-susceptible mycobacteria.
Topics: Aminosalicylic Acids; Animals; Antitubercular Agents; Cycloserine; Ethambutol; Ethionamide; Isoniazid; Kanamycin; Male; Mice; Mycobacterium; Pyrazinamide; Streptomycin; Tuberculosis | 1967 |
Comparative studies of various antituberculosis drug regimens by means of serum antimycobacterial activity tests in man.
Topics: Adolescent; Adult; Aminoisobutyric Acids; Antitubercular Agents; Cycloserine; Drug Resistance, Microbial; Ethambutol; Ethionamide; Female; Humans; Isoniazid; Kanamycin; Male; Middle Aged; Phenylthiourea; Pyrazinamide; Streptomycin; Tuberculosis, Pulmonary | 1967 |
Toxicity of pyrazinamide, administered once weekly in high dosage, in tuberculous patients.
Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Bilirubin; Blood Chemical Analysis; Female; Humans; Isoniazid; Male; Pyrazinamide; Streptomycin; Time Factors; Tuberculosis, Pulmonary; Urobilin | 1968 |
Retreatment of tuberculosis patients with combined drug therapy.
Topics: Brazil; Cycloserine; Drug Resistance, Microbial; Ethionamide; Humans; Isoniazid; Pyrazinamide; Tuberculosis | 1969 |
[Improved therapy of tuberculosis with a well tolerated INH derivative (INHG)].
Topics: Cycloserine; Ethambutol; Ethionamide; Glucuronates; Humans; Isoniazid; Middle Aged; Pyrazinamide; Streptomycin; Tuberculosis, Pulmonary | 1969 |
Chronic tuberculosis in refractory patients--therapeutic aspects.
Topics: Aminosalicylic Acids; Antitubercular Agents; Chronic Disease; Cycloserine; Drug Resistance, Microbial; Ethionamide; Hospitalization; Humans; Isoniazid; Male; Pneumonectomy; Pyrazinamide; Social Behavior Disorders; Socioeconomic Factors; Streptomycin; Time Factors; Tuberculosis, Pulmonary | 1969 |
[Comparative evaluation of several functional tests of the liver in patients with pulmonary tuberculosis with side-reactions to tuberculostatic preparations].
Topics: Adult; Antitubercular Agents; Cycloserine; Ethionamide; Female; Humans; Isoniazid; Kanamycin; Liver; Liver Function Tests; Male; Middle Aged; Pyrazinamide; Streptomycin; Tuberculosis, Pulmonary | 1969 |
[Liver function in tuberculosis treated with pyrazinamide, cycloserine, ethionamide and isoniazid].
Topics: Antitubercular Agents; Cycloserine; Ethionamide; Humans; Isoniazid; Liver; Pyrazinamide; Tuberculosis | 1969 |
Problems of treatment of drug resistance in the developing countries.
Topics: Africa; Aminosalicylic Acids; Antitubercular Agents; Costs and Cost Analysis; Developing Countries; Drug Resistance, Microbial; Ethionamide; Humans; India; Isoniazid; Pyrazinamide; Streptomycin; Tuberculosis | 1969 |
[Attempt at intermittent chemotherapeutic treatment of patients with bacilli resistant to streptomycin and isoniazid (cooperative survey by the antitubercular services of Marrakech, Meknes, Tangiers)].
Topics: Cycloserine; Drug Resistance, Microbial; Drug Synergism; Ethionamide; Humans; Isoniazid; Morocco; Pyrazinamide; Streptomycin; Time Factors; Tuberculosis | 1969 |
Ethambutol in the retreatment of chronic pulmonary tuberculosis.
Topics: Aminosalicylic Acids; Chronic Disease; Cycloserine; Depression, Chemical; Drug Synergism; Ethambutol; Ethionamide; Humans; Isoniazid; Kanamycin; Pyrazinamide; Sputum; Streptomycin; Tuberculosis, Pulmonary | 1970 |
Thrombocytopenia and sideroblastic anemia with pyrazinoic acid amide (pyrazinamide) therapy.
Topics: Adolescent; Adult; Aged; Aminosalicylic Acids; Anemia, Sideroblastic; Antitubercular Agents; Cycloserine; Female; Humans; Iron; Isoniazid; Middle Aged; Protein Binding; Pyrazinamide; Streptomycin; Thrombocytopenia | 1970 |
[Drug therapy of urogenital tuberculosis].
Topics: Aminosalicylic Acids; Cycloserine; Drug Synergism; Ethambutol; Ethionamide; Female; Humans; Isoniazid; Phenylthiourea; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Urogenital | 1970 |
[Comparative study of specific blood activity in patients with fibrous-cavernous pulmonary tuberculosis during administration of different combinations of antibacterial preparations].
Topics: Blood Bactericidal Activity; Cycloserine; Ethionamide; Humans; Isoniazid; Pyrazinamide; Time Factors; Tuberculosis, Pulmonary | 1970 |
Clinical experience with Myambutol in the treatment of polyresistant chronic tuberculosis.
Topics: Adult; Cycloserine; Drug Combinations; Ethambutol; Ethionamide; Female; Humans; Isoniazid; Kanamycin; Male; Middle Aged; Phenylthiourea; Pyrazinamide; Streptomycin; Time Factors; Tuberculosis, Pulmonary | 1970 |
Surgical appraoches to the anterior aspect of the spinal column.
Topics: Abscess; Adult; Aged; Aminosalicylic Acids; Bronchial Neoplasms; Carcinoma; Child; Female; Humans; Intervertebral Disc Displacement; Isoniazid; Joint Dislocations; Male; Middle Aged; Neoplasm Metastasis; Osteomyelitis; Paraplegia; Plasmacytoma; Pyrazinamide; Scheuermann Disease; Spinal Diseases; Spinal Neoplasms; Staphylococcal Infections; Streptomycin; Tuberculosis, Spinal | 1971 |
[Toxicity of the primary tuberculostatics].
Topics: Aminosalicylic Acids; Antitubercular Agents; Cycloserine; Humans; Isoniazid; Pyrazinamide; Streptomycin; Tuberculosis, Pulmonary | 1967 |
[Contributions on the use of pyrazinamide].
Topics: Adult; Female; Humans; Isoniazid; Lupus Vulgaris; Male; Pyrazinamide; Tuberculosis, Cutaneous | 1967 |
Re-treatment of patients with isoniazid-resistant tuberculosis. Analysis and follow-up of 146 cases.
Topics: Adult; Antitubercular Agents; Cycloserine; Drug Resistance, Microbial; Drug Synergism; Ethionamide; Follow-Up Studies; Humans; Isoniazid; Kanamycin; Pyrazinamide | 1968 |
The use of second line drugs in patients with drug resistance to standard tuberculostatics.
Topics: Ambulatory Care; Aminosalicylic Acids; Antitubercular Agents; Cycloserine; Drug Hypersensitivity; Drug Resistance, Microbial; Ethionamide; Humans; Isoniazid; Pyrazinamide; Sputum; Streptomycin; Tuberculosis, Pulmonary | 1968 |
[Certain aspects of new combinations of drugs for the treatment of drug-resistant tuberculosis].
Topics: Aminosalicylic Acids; Antitubercular Agents; Drug Resistance, Microbial; Ethionamide; Humans; Isoniazid; Pyrazinamide; Tuberculosis, Pulmonary | 1968 |
[New combinations of drugs for the treatment of drug-resistant tuberculosis].
Topics: Aminosalicylic Acids; Antitubercular Agents; Drug Resistance, Microbial; Ethionamide; Humans; Isoniazid; Pyrazinamide; Streptomycin; Tuberculosis | 1968 |
Observations on human infection with Mycobacterium bovis.
Topics: Adolescent; Adult; Aged; Aminosalicylic Acids; Animals; Cattle; Drug Resistance, Microbial; Humans; Isoniazid; Middle Aged; Pyrazinamide; Species Specificity; Streptomycin; Tuberculosis, Bovine; Tuberculosis, Pulmonary | 1969 |
[On qualitative demonstration of tuberculostatics in the control of taking of drugs].
Topics: Aminosalicylic Acids; Cycloserine; Ethionamide; Humans; Isoniazid; Pyrazinamide; Streptomycin; Tuberculosis, Pulmonary | 1965 |
Reversible sideroblastic anemia caused by pyrazinoic acid (Pyrazinamide).
Topics: Adult; Aminosalicylic Acids; Anemia; Anemia, Sideroblastic; Erythropoiesis; Ethionamide; Female; Folic Acid Deficiency; Glucosephosphate Dehydrogenase Deficiency; Humans; In Vitro Techniques; Isoniazid; Prednisolone; Pyrazinamide; Pyridoxine; Streptomycin; Tuberculosis, Pulmonary; Vitamin B 12 | 1966 |
[On the effect of tuberculostatics on the endogenous metabolism of mycobacteria].
Topics: Aminosalicylic Acids; Antitubercular Agents; Buffers; Cycloserine; Ethionamide; Isoniazid; Mycobacterium; Phosphorus Isotopes; Pyrazinamide; Streptomycin | 1966 |
Addendum on serum levels.
Topics: Aminosalicylic Acids; Anti-Bacterial Agents; Antitubercular Agents; Cycloserine; Drug Resistance, Microbial; Ethambutol; Ethionamide; Humans; Isoniazid; Phenazines; Pyrazinamide; Rifampin; Streptomycin | 1967 |
The steady state in cellular immunity. I. Chemotherapy and superinfection in murine tuberculosis.
Topics: Animals; Antitubercular Agents; Feedback; Female; In Vitro Techniques; Isoniazid; Mice; Pyrazinamide; Tuberculin Test; Virulence | 1967 |
Determination of isonicotinic acid hydrazide in blood serum.
Topics: Cycloserine; Humans; Indicators and Reagents; Isoniazid; Pyrazinamide; Spectrophotometry; Tuberculosis | 1967 |
Pulmonary alveolar proteinosis. Treatment in a case complicated by tuberculosis.
Topics: Acetylcysteine; Aminosalicylic Acids; Cycloserine; Ethionamide; Heparin; Humans; Isoniazid; L-Lactate Dehydrogenase; Lipids; Male; Middle Aged; Pulmonary Alveolar Proteinosis; Pyrazinamide; Radiography, Thoracic; Respiratory Function Tests; Therapeutic Irrigation; Tuberculosis, Pulmonary | 1967 |
Pyrazinamide-isoniazid: its apparent influence on the reactivation rate in pulmonary tuberculosis.
Topics: Adult; Aminosalicylic Acids; Chemical and Drug Induced Liver Injury; Humans; Isoniazid; Middle Aged; Pyrazinamide; Tuberculosis, Pulmonary | 1967 |
Drug-resistant Mycobacterium tuberculosis in Korean isolates.
Topics: Adult; Capreomycin; Drug Resistance, Microbial; Ethambutol; Humans; Isoniazid; Korea; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Pulmonary | 1982 |
[Current treatment of pulmonary tuberculosis].
Topics: Adult; Aged; Antitubercular Agents; Child; Ethambutol; Humans; Isoniazid; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 1984 |
Compliance of patients and physicians: experience and lessons from tuberculosis-II.
Topics: Attitude of Health Personnel; Drug Administration Schedule; Drug Information Services; Drug Therapy, Combination; Education, Medical, Graduate; Family Practice; Humans; Isoniazid; Patient Compliance; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Pulmonary; United Kingdom | 1983 |
[Pharmacokinetics of antitubercular agents in man].
Topics: Absorption; Antitubercular Agents; Half-Life; Humans; Isoniazid; Kinetics; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Streptomycin; Time Factors; Tuberculosis, Pulmonary | 1984 |
[Short-course chemotherapy for tuberculosis in Chile. Operational considerations].
Topics: Antitubercular Agents; Drug Administration Schedule; Drug Therapy, Combination; Humans; Isoniazid; Patient Dropouts; Pyrazinamide; Recurrence; Rifampin; Streptomycin; Tuberculosis, Pulmonary | 1984 |
[Short-course treatment of tuberculosis on a 7-month schedule with an initial intensive phase of 1 month (TA-81)].
Topics: Antitubercular Agents; Drug Administration Schedule; Drug Therapy, Combination; Follow-Up Studies; Humans; Isoniazid; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Pulmonary | 1984 |
A successful supervised outpatient short-course tuberculosis treatment program in an open refugee camp on the Thai-Cambodian border.
Topics: Adolescent; Adult; Ambulatory Care Facilities; Antitubercular Agents; Cambodia; Child; Drug Therapy, Combination; Female; Humans; Isoniazid; Male; Middle Aged; Patient Compliance; Pyrazinamide; Refugees; Rifampin; Streptomycin; Thailand; Time Factors; Tuberculosis, Pulmonary | 1984 |
Appearance of tuberculoma during the course of TB meningitis.
Topics: Adolescent; Brain Stem; Female; Humans; Isoniazid; Prednisolone; Pyrazinamide; Rifampin; Tomography, X-Ray Computed; Tuberculoma; Tuberculosis, Meningeal | 1984 |
[Tuberculosis treatment today].
Topics: Antitubercular Agents; Ethambutol; Humans; Isoniazid; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Pulmonary | 1984 |
The management of genito-urinary tuberculosis--a review.
Topics: Angiography; Antitubercular Agents; Developing Countries; Drug Therapy, Combination; Endoscopy; Epididymis; Female; Humans; Isoniazid; Male; Nephrectomy; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Urogenital; Urinary Diversion; Urography | 1984 |
[Studies on short-course chemotherapy of tuberculosis. II. Liver function during 6-month chemotherapy of tuberculosis with hydrazide, rifampicin and pyrazinamide].
Topics: Humans; Isoniazid; Liver; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 1984 |
The management of urinary tuberculosis--a logical approach.
Topics: Adult; Aged; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Tuberculosis, Urogenital | 1984 |
Genitourinary tuberculosis. A study of 1117 cases over a period of 34 years.
Topics: Adult; Antitubercular Agents; Drug Therapy, Combination; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Urogenital; Urine | 1984 |
The tolerability and efficacy of a 6-month antituberculosis regimen containing rifampicin, isoniazid and pyrazinamide.
Topics: Adolescent; Adult; Drug Therapy, Combination; Drug Tolerance; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Time Factors; Tuberculosis, Pulmonary | 1983 |
[Comparison of 3 6-month chemotherapy regimes in pulmonary tuberculosis in routine practice in Algiers. 18th-month results].
Topics: Adolescent; Adult; Antitubercular Agents; Drug Evaluation; Drug Resistance, Microbial; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Male; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 1983 |
[Activity of intermittently administered rifampicin and cyclopentyl rifamycin (or DL473) on experimental tuberculosis in the mouse].
Topics: Animals; DNA-Directed RNA Polymerases; Drug Therapy, Combination; Female; Isoniazid; Mice; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis | 1983 |
[Short-term treatment of tuberculosis with and without pyrazinamide in the second phase (TA-80)].
Topics: Antitubercular Agents; Drug Therapy, Combination; Humans; Isoniazid; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Pulmonary | 1983 |
The treatment of urinary tuberculosis.
Topics: Adult; Aged; Ethambutol; Female; Follow-Up Studies; Humans; Isoniazid; Kidney; Male; Methods; Middle Aged; Pyrazinamide; Rifampin; Tuberculosis, Urogenital; Ureter; Urinary Bladder; Urinary Tract; Urography | 1984 |
Shortest possible acceptable effective chemotherapy in ambulatory patients with pulmonary tuberculosis. Part II. Results during the 24 months after the end of chemotherapy.
Topics: Ambulatory Care; Antitubercular Agents; Drug Administration Schedule; Drug Therapy, Combination; Ethionamide; Follow-Up Studies; Humans; India; Isoniazid; Patient Compliance; Pyrazinamide; Random Allocation; Rifampin; Streptomycin; Time Factors; Tuberculosis, Pulmonary | 1984 |
The early bactericidal activity of drugs in patients with pulmonary tuberculosis.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Isoniazid; Microbial Sensitivity Tests; Middle Aged; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Time Factors; Tuberculosis, Pulmonary | 1980 |
Studies in short-course chemotherapy for tuberculosis. Basis for short-course chemotherapy.
Topics: Animals; Drug Therapy, Combination; Humans; Isoniazid; Mice; Mice, Inbred Strains; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Streptomycin; Time Factors; Tuberculosis, Pulmonary | 1981 |
[Sterilizing activity of the main drugs on the mouse experimental tuberculosis (author's transl)].
Topics: Animals; Antibiotics, Antitubercular; Drug Therapy, Combination; Female; Humans; Isoniazid; Lung; Mice; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Spleen; Streptomycin; Tuberculosis | 1982 |
Present chemotherapy for tuberculosis.
Topics: Antitubercular Agents; Drug Resistance, Microbial; Ethambutol; Humans; Isoniazid; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis | 1982 |
Tuberculosis therapy.
Topics: Chemical and Drug Induced Liver Injury; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; Isoniazid; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Pulmonary | 1983 |
Antituberculous agents. Isoniazid, rifampin, streptomycin, ethambutol, and pyrazinamide.
Topics: Antitubercular Agents; Ethambutol; Humans; Isoniazid; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis | 1983 |
Hepatic complications of antituberculosis therapy revisited.
Topics: Adolescent; Adult; Aged; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Infant; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 1983 |
Adverse effects of antituberculosis drugs causing changes in treatment.
Topics: Antitubercular Agents; Humans; Isoniazid; Kanamycin; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Pulmonary | 1982 |
Phenytoin toxicity induced by antituberculosis drugs.
Topics: Adult; Drug Interactions; Humans; Isoniazid; Male; Phenytoin; Pyrazinamide | 1982 |
Successful intermittent treatment of smear-positive pulmonary tuberculosis in six months: a cooperative study in Poland.
Topics: Adolescent; Adult; Aged; Drug Therapy, Combination; Follow-Up Studies; Humans; Isoniazid; Middle Aged; Poland; Pyrazinamide; Rifampin; Streptomycin; Time Factors; Tuberculosis, Pulmonary | 1982 |
Short-course chemotherapy for pulmonary tuberculosis. Points of interest.
Topics: Adult; Ambulatory Care; Child, Preschool; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Isoniazid; Pyrazinamide; Rifampin; Streptomycin; Time Factors; Tuberculosis, Pulmonary | 1982 |
Modern treatment of tuberculosis.
Topics: Antitubercular Agents; Drug Administration Schedule; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; Isoniazid; Pyrazinamide; Rifampin; Streptomycin; Time Factors; Tuberculosis; Tuberculosis, Pulmonary | 1982 |
[Mycobacterium malmoense in the Federal Republic of Germany].
Topics: Aged; Agglutination Tests; Amides; Germany, West; Humans; Hydrolases; Isoniazid; Lipids; Male; Middle Aged; Mycobacterium; Mycobacterium Infections, Nontuberculous; Nitrates; Nontuberculous Mycobacteria; Pyrazinamide; Tuberculosis, Pulmonary | 1982 |
Current concept of short-term chemotherapy of tuberculosis.
Topics: Drug Combinations; Ethambutol; Humans; Isoniazid; Pyrazinamide; Rifampin; Time Factors; Tuberculosis | 1981 |
Shortest possible acceptable, effective ambulatory chemotherapy in pulmonary tuberculosis: preliminary report I.
Topics: Ambulatory Care; Antitubercular Agents; Drug Administration Schedule; Ethionamide; Female; Humans; Isoniazid; Male; Pyrazinamide; Radiography; Rifampin; Streptomycin; Tuberculosis, Pulmonary | 1981 |
[Adverse reactions to short-course anti-tuberculous therapy (author's transl)].
Topics: Antitubercular Agents; Drug Hypersensitivity; Drug Tolerance; Humans; Isoniazid; Pyrazinamide; Rifampin; Streptomycin | 1981 |
[Clinically apparent liver damage during brief tuberculosis therapy].
Topics: Acute Disease; Adult; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Female; Humans; Isoniazid; Liver; Male; Middle Aged; Pyrazinamide; Rifampin; Streptomycin | 1981 |
Tuberculosis in patients with end-stage renal disease.
Topics: Adult; Aged; Ethambutol; Female; Humans; Immunity, Cellular; Isoniazid; Kidney Failure, Chronic; Male; Middle Aged; Pyrazinamide; Renal Dialysis; Rifampin; Risk; Tuberculosis | 1980 |
Isoniazid interaction with tyrosine as a possible mode of action of the drug in mycobacteria.
Topics: Culture Media; Electron Transport; Isoniazid; Mycobacterium; Mycobacterium phlei; NADH Dehydrogenase; NADH, NADPH Oxidoreductases; Pyrazinamide; Time Factors; Tyrosine | 1980 |
Monitoring regularity of drug intake in tuberculous patients by means of simple urine tests.
Topics: Color; Drug Administration Schedule; Humans; Isoniazid; Patient Compliance; Pyrazinamide; Rifampin; Time Factors; Tuberculosis, Pulmonary; Urine | 1980 |
A service program of antituberculosis chemotherapy with five drugs for four months in the treatment of drug addicts and prisoners with pulmonary tuberculosis in Hong Kong. Hong Kong Chest Service/British Medical Research Council.
Topics: Antitubercular Agents; Drug Administration Schedule; Drug Resistance, Microbial; Ethambutol; Heroin Dependence; Hong Kong; Humans; Isoniazid; Male; Opioid-Related Disorders; Opium; Prisoners; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis; Tuberculosis, Pulmonary | 1980 |
Controlled double-blind study of the effect of rifampin on humoral and cellular immune responses in patients with pulmonary tuberculosis and in tuberculosis contacts.
Topics: Adolescent; Adult; Antibody Formation; Double-Blind Method; Female; Humans; Immunity, Cellular; Isoniazid; Leukocytes; Lymphocyte Activation; Male; Middle Aged; Pyrazinamide; Rifampin; Skin Tests; Streptomycin; Tuberculosis, Pulmonary | 1980 |
[Side effects of various combinations of rifampin and isoniazid with ethambutol or streptomycin and pyrazinamide in short-term chemotherapy of newly-detected pulmonary tuberculosis].
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Drug Administration Schedule; Drug Hypersensitivity; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Middle Aged; Pyrazinamide; Rifampin; Streptomycin; Time Factors; Tuberculosis, Pulmonary | 1980 |
Hepatotoxicity associated with acetaminophen usage in patients receiving multiple drug therapy for tuberculosis.
Topics: Acetaminophen; Adult; Capreomycin; Ciprofloxacin; Drug Combinations; Drug Overdose; Ethambutol; Female; Humans; Isoniazid; Liver; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis; Tuberculosis, Lymph Node; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 1994 |
Oxidative stress during antituberculous therapy in young and elderly patients.
Topics: Adult; Age Factors; Aged; Allantoin; Antitubercular Agents; Drug Therapy, Combination; Female; Humans; Isoniazid; Male; Oxidative Stress; Pyrazinamide; Rifampin; Thiobarbituric Acid Reactive Substances; Time Factors; Tuberculosis, Pulmonary; Uric Acid | 1995 |
Relapse rates in tuberculosis patients.
Topics: Antitubercular Agents; Drug Combinations; Ethambutol; Female; Follow-Up Studies; Humans; Isoniazid; Male; Patient Compliance; Pyrazinamide; Recurrence; Rifampin; Tuberculosis, Pulmonary | 1995 |
Drugs for tuberculosis.
Topics: Adult; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Combinations; Ethambutol; Humans; Isoniazid; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 1995 |
Brief report: meningitis due to iatrogenic BCG infection in two immunocompromised children.
Topics: Antineoplastic Combined Chemotherapy Protocols; Antitubercular Agents; Child, Preschool; Drug Contamination; Ethionamide; Female; Humans; Iatrogenic Disease; Immunocompromised Host; Isoniazid; Male; Meningitis, Bacterial; Mycobacterium bovis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Meningeal | 1995 |
Ethambutol-induced pulmonary infiltrates with eosinophilia and skin involvement.
Topics: Aged; Drug Eruptions; Drug Therapy, Combination; Eosinophilia; Ethambutol; Female; Humans; Isoniazid; Pulmonary Eosinophilia; Pyrazinamide; Radiography; Rifampin; Streptomycin; Thrombocytopenia; Tuberculosis, Miliary | 1995 |
Deleterious influence of pyrazinamide on the outcome of patients with fulminant or subfulminant liver failure during antituberculous treatment including isoniazid.
Topics: Adolescent; Adult; Aged; Drug Therapy, Combination; Female; Hepatic Encephalopathy; Humans; Isoniazid; Liver Transplantation; Male; Middle Aged; Pyrazinamide; Rifampin; Survival Rate | 1995 |
Anti tubercular treatment induced hepatotoxicity: does acetylator status matter?
Topics: Acetylation; Adult; Antitubercular Agents; Biomarkers; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Isoniazid; Liver; Liver Function Tests; Male; Middle Aged; Phenotype; Pyrazinamide; Rifampin | 1995 |
[Lupus vulgaris. Treatment with 3 drugs].
Topics: Aged; Antitubercular Agents; Drug Therapy, Combination; Female; Humans; Isoniazid; Lupus Vulgaris; Male; Pyrazinamide; Rifampin | 1995 |
Short-course chemotherapy for tuberculous pleural effusion and culture-negative pulmonary tuberculosis.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Antitubercular Agents; Drug Therapy, Combination; Female; Humans; Isoniazid; Male; Middle Aged; Pleural Effusion; Pyrazinamide; Rifampin; Self Administration; Tuberculosis, Pulmonary | 1995 |
Silicotuberculosis: long-term outcome after short-course chemotherapy.
Topics: Adult; Antitubercular Agents; Drug Therapy, Combination; Follow-Up Studies; Humans; Isoniazid; Male; Pyrazinamide; Recurrence; Rifampin; Silicotuberculosis; Streptomycin; Tuberculosis, Pulmonary | 1995 |
Antituberculous therapy and acute liver failure.
Topics: Antitubercular Agents; Drug Therapy, Combination; Hepatic Encephalopathy; Humans; Isoniazid; Liver Failure, Acute; Liver Transplantation; Pyrazinamide | 1995 |
Antituberculous therapy and acute liver failure.
Topics: Adult; Antitubercular Agents; Drug Hypersensitivity; Female; Humans; Isoniazid; Liver Failure, Acute; Liver Function Tests; Male; Middle Aged; Pyrazinamide; Rifampin | 1995 |
Antituberculous therapy and acute liver function.
Topics: Antitubercular Agents; Clinical Trials as Topic; Drug Therapy, Combination; Hong Kong; Humans; Isoniazid; Liver Function Tests; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Pulmonary | 1995 |
[Tuberculous dacryocystitis].
Topics: Acute Disease; Child, Preschool; Dacryocystitis; Dacryocystorhinostomy; Humans; Isoniazid; Male; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Tuberculosis | 1995 |
Drug resistance of Mycobacterium tuberculosis strains isolated from HIV-infected Italian patients: preliminary report from a multicentric study. The Italian Tuberculosis Drug Resistance Study Group.
Topics: Antitubercular Agents; Drug Resistance, Microbial; Ethambutol; HIV Infections; Humans; Isoniazid; Italy; Mycobacterium tuberculosis; Prospective Studies; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Multidrug-Resistant | 1995 |
[Therapy of tuberculosis in the adult].
Topics: Adult; AIDS-Related Opportunistic Infections; Antitubercular Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Pyrazinamide; Rifampin; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 1995 |
Replacement of one lung by a large bulla in active tuberculosis.
Topics: Aged; Drug Therapy, Combination; Humans; Isoniazid; Male; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 1995 |
Antituberculous therapy and acute liver function.
Topics: Adult; Antitubercular Agents; Drug Therapy, Combination; Fatal Outcome; Female; Humans; Isoniazid; Liver Function Tests; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 1995 |
[Tuberculous abscess of the liver. Apropos of 2 cases].
Topics: Adult; Diagnosis, Differential; Drug Therapy, Combination; Female; Humans; Isoniazid; Liver Abscess; Pyrazinamide; Rifampin; Tuberculosis, Hepatic | 1994 |
Transient exacerbation of tuberculous lymphadenitis during chemotherapy in patients with AIDS.
Topics: Adult; AIDS-Related Opportunistic Infections; Antitubercular Agents; Ethambutol; Humans; Isoniazid; Leukocyte Count; Male; Pyrazinamide; Rifampin; Tuberculosis, Lymph Node; Tuberculosis, Multidrug-Resistant | 1994 |
Comprehensive assay for pyrazinamide, rifampicin and isoniazid with its hydrazine metabolites in human plasma by column liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Female; Humans; Hydrazines; Isoniazid; Middle Aged; Pyrazinamide; Rifampin; Spectrophotometry, Ultraviolet | 1994 |
Treating tuberculosis with one combination drug.
Topics: Antitubercular Agents; Drug Combinations; Ethambutol; Humans; Isoniazid; Patient Compliance; Pyrazinamide; Rifampin; Tuberculosis | 1994 |
Activity of KRM-1648, a new benzoxazinorifamycin, against Mycobacterium tuberculosis in a murine model.
Topics: Animals; Antibiotics, Antitubercular; Drug Therapy, Combination; Female; Isoniazid; Mice; Pyrazinamide; Rifabutin; Rifampin; Rifamycins; Tuberculosis | 1994 |
Empiric antituberculosis treatment: benefits for earlier diagnosis and treatment of tuberculosis.
Topics: Adult; AIDS-Related Opportunistic Infections; Antitubercular Agents; Body Weight; Drug Administration Schedule; Drug Therapy, Combination; Ethambutol; Female; Fever; Follow-Up Studies; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Time Factors; Treatment Outcome; Tuberculosis | 1994 |
[Pulmonary tuberculosis in infants. Apropos of 6 cases].
Topics: BCG Vaccine; Drug Therapy, Combination; Ethambutol; Female; Humans; Infant; Isoniazid; Male; Pyrazinamide; Radiography; Rifampin; Tuberculosis, Pulmonary | 1994 |
[Effects of antibacterial preparations on growth of Mycobacterium tuberculosis in a model of primary tuberculous infection in tissue culture].
Topics: Animals; Bacteriological Techniques; Culture Media; Culture Techniques; Isoniazid; Lung; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Time Factors | 1994 |
Cytogenetic study of tuberculosis patients before and after tuberculostatic drug treatment.
Topics: Adult; Antitubercular Agents; Cell Division; Chromosome Aberrations; Drug Combinations; Female; Humans; Isoniazid; Lymphocytes; Male; Middle Aged; Mitotic Index; Mutagens; Pyrazinamide; Rifampin; Sister Chromatid Exchange; Tuberculosis, Pulmonary | 1995 |
Isoniazid is not always the cause of hepatitis during treatment of tuberculosis.
Topics: Chemical and Drug Induced Liver Injury; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Tuberculosis, Pulmonary | 1994 |
4-, 5- and 6-month regimens containing isoniazid, rifampicin, pyrazinamide and streptomycin for treatment of pulmonary tuberculosis under program conditions in Hong Kong.
Topics: Adolescent; Adult; Antitubercular Agents; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Isoniazid; Male; Middle Aged; Patient Compliance; Pyrazinamide; Recurrence; Retrospective Studies; Rifampin; Streptomycin; Treatment Failure; Tuberculosis, Pulmonary | 1994 |
Preventive therapy of tuberculosis with rifapentine in immunocompetent and nude mice.
Topics: Animals; Antitubercular Agents; Colony-Forming Units Assay; Drug Therapy, Combination; Female; Immunity; Isoniazid; Mice; Mice, Nude; Pyrazinamide; Rifampin; Tuberculosis | 1994 |
Early bactericidal activity as a method of assessment of drugs for the treatment of tuberculosis.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Evaluation, Preclinical; Isoniazid; Microbial Sensitivity Tests; Predictive Value of Tests; Pyrazinamide; Rifabutin; Time Factors; Tuberculosis | 1994 |
[Sacral tuberculous osteitis].
Topics: Child, Preschool; Drug Therapy, Combination; Humans; Isoniazid; Magnetic Resonance Imaging; Male; Osteitis; Pyrazinamide; Rifampin; Sacrum; Tuberculosis, Spinal | 1994 |
[Endoscopic diagnosis of colonic tuberculosis].
Topics: Aged; Cecum; Colon; Colonic Diseases; Colonoscopy; Drug Therapy, Combination; Female; Humans; Isoniazid; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Tuberculosis, Gastrointestinal | 1994 |
Treatment of tuberculosis and tuberculosis infection in adults and children. American Thoracic Society.
Topics: Adolescent; Adult; AIDS-Related Opportunistic Infections; Antitubercular Agents; Child; Clinical Protocols; Drug Monitoring; Ethambutol; Humans; Infant; Isoniazid; Patient Compliance; Pyrazinamide; Recurrence; Rifampin; Streptomycin; Tuberculosis; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 1994 |
[Two pulmonary tuberculosis cases with HIV infection].
Topics: Adult; Female; HIV Infections; Humans; Isoniazid; Male; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Pulmonary | 1994 |
Clinical features, diagnosis, and treatment of tuberculosis in infants.
Topics: Drug Therapy, Combination; Female; Humans; Infant; Isoniazid; Male; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 1994 |
[Tuberculous meningitis caused by resistant microorganisms. Therapeuticfailure in 2 patients with HIV infection and disseminated tuberculosis].
Topics: Adult; AIDS-Related Opportunistic Infections; Antitubercular Agents; Drug Resistance, Microbial; Drug Therapy, Combination; Fatal Outcome; Humans; Isoniazid; Male; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Meningeal; Zidovudine | 1994 |
From the Food and Drug Administration.
Topics: Antitubercular Agents; Blood Donors; Drug Approval; Drug Combinations; Electromagnetic Phenomena; Equipment and Supplies; Equipment Failure; HIV Infections; HIV Seronegativity; Humans; Isoniazid; Pyrazinamide; Rifampin; Tuberculosis; United States; United States Food and Drug Administration; Wheelchairs | 1994 |
Human immunodeficiency virus type-1 infection in Zambian children with tuberculosis: changing seroprevalence and evaluation of a thioacetazone-free regimen.
Topics: Adolescent; Child; Child, Preschool; Drug Hypersensitivity; Drug Therapy, Combination; Female; HIV Infections; HIV Seroprevalence; HIV-1; Humans; Infant; Isoniazid; Male; Prospective Studies; Pyrazinamide; Rifampin; Streptomycin; Treatment Outcome; Tuberculosis, Pulmonary; Zambia | 1994 |
Papulonecrotic tuberculide and erythema induratum as presenting manifestations of tuberculosis.
Topics: Adult; Asia; Drug Therapy, Combination; Erythema Induratum; Female; Humans; Isoniazid; Pyrazinamide; Rifampin; Tuberculosis, Cutaneous; United Kingdom | 1994 |
Rifampin-resistant Mycobacterium kansasii.
Topics: Adult; Aged; Aged, 80 and over; Amikacin; Antitubercular Agents; Ciprofloxacin; Clinical Protocols; Drug Resistance, Microbial; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Mycobacterium Infections, Nontuberculous; Nontuberculous Mycobacteria; Pyrazinamide; Pyridoxine; Rifampin; Streptomycin; Texas; Treatment Outcome; Tuberculosis | 1994 |
Follow-up of tuberculosis patients undergoing standard anti-tuberculosis chemotherapy by using a polymerase chain reaction.
Topics: Anti-Bacterial Agents; Drug Therapy, Combination; Follow-Up Studies; Humans; Isoniazid; Mycobacterium tuberculosis; Polymerase Chain Reaction; Pyrazinamide; Rifampin; Sputum; Tuberculosis, Pulmonary | 1994 |
Genito-urinary tuberculosis--experience with 52 urology inpatients.
Topics: Adolescent; Adult; Aged; Child; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Urogenital; Ureteral Obstruction | 1993 |
Serum concentrations of rifampicin and isoniazid in tuberculosis.
Topics: Adolescent; Child; Child, Preschool; Drug Therapy, Combination; Female; Half-Life; Humans; Infant; Isoniazid; Male; Pyrazinamide; Rifampin; Time Factors; Tuberculosis, Meningeal; Tuberculosis, Pulmonary | 1993 |
Short course chemotherapy for tuberculosis in children.
Topics: Adolescent; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Infant; Infant, Newborn; Isoniazid; Male; Pyrazinamide; Rifampin; Skin Diseases; Streptomycin; Tuberculosis; Vomiting | 1993 |
Hepatotoxicity of antituberculosis therapy (rifampicin, isoniazid and pyrazinamide) or viral hepatitis.
Topics: Acute Disease; Adolescent; Adult; Chemical and Drug Induced Liver Injury; Diagnosis, Differential; Drug Therapy, Combination; Female; Hepatitis B; Hepatitis C; Hepatitis, Viral, Human; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin | 1994 |
Treatment of tuberculosis in patients with pre-existing liver disease or following hepatotoxic drug reactions.
Topics: Chemical and Drug Induced Liver Injury; Clinical Protocols; Contraindications; Humans; Isoniazid; Liver Diseases; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 1993 |
[Hepatic toxicity of antitubercular agents. Role of different drugs. 199 cases].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Therapy, Combination; Ethambutol; Female; Humans; Infant; Isoniazid; Male; Middle Aged; Pyrazinamide; Retrospective Studies; Rifampin; Streptomycin; Tuberculosis | 1993 |
Turning intermittent regimens into daily regimens using blister-packs. An exploration in murine tuberculosis.
Topics: Animals; Antitubercular Agents; Drug Administration Schedule; Drug Packaging; Drug Therapy, Combination; Ethambutol; Isoniazid; Mice; Mice, Inbred BALB C; Pyrazinamide; Rifampin; Tuberculosis | 1993 |
Therapeutic monitoring of antituberculosis drugs by direct in-line extraction on a high-performance liquid chromatography system.
Topics: Antitubercular Agents; Chromatography, High Pressure Liquid; Drug Monitoring; Ethionamide; Humans; Isoniazid; Pyrazinamide; Spectrophotometry, Ultraviolet; Tuberculosis, Meningeal; Xenobiotics | 1993 |
Determination of iron by the Ferrochem II: interference by tuberculostatics.
Topics: Antitubercular Agents; Drug Combinations; Electrochemistry; Humans; Iron; Isoniazid; Pyrazinamide; Rifampin; Spectrophotometry, Atomic | 1993 |
Drug-resistant tuberculosis.
Topics: Drug Resistance, Microbial; Humans; Isoniazid; Pyrazinamide; Rifampin; Tuberculosis, Multidrug-Resistant | 1993 |
Ocular lesions of tuberculosis.
Topics: Adolescent; Choroid Diseases; Drug Combinations; Female; Humans; Infant; Isoniazid; Male; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Meningeal; Tuberculosis, Ocular | 1993 |
[Clinical aspects and outcome of recurrent pulmonary tuberculosis].
Topics: Drug Therapy, Combination; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Recurrence; Rifampin; Streptomycin; Treatment Outcome; Tuberculosis, Pulmonary | 1993 |
Chemotherapy of tuberculosis for patients with renal impairment.
Topics: Antitubercular Agents; Ethambutol; Humans; Isoniazid; Kidney Failure, Chronic; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Pulmonary | 1993 |
Cost-effectiveness analysis of three short-course anti-tuberculosis programmes compared with a standard regimen in Thailand.
Topics: Adolescent; Adult; Antitubercular Agents; Cost-Benefit Analysis; Drug Administration Schedule; Female; Humans; Isoniazid; Male; Pyrazinamide; Rifampin; Thailand; Tuberculosis, Pulmonary | 1993 |
Cervical tuberculous vertebral osteomyelitis: case report and discussion of the literature.
Topics: Adult; Cervical Vertebrae; Drug Therapy, Combination; Humans; Isoniazid; Male; Pyrazinamide; Rifampin; Tomography, X-Ray Computed; Tuberculosis, Spinal | 1993 |
From the Centers for Disease Control and Prevention. Initial therapy for tuberculosis in the era of multidrug resistance: recommendations of the Advisory Council for the Elimination of Tuberculosis.
Topics: Adult; Antitubercular Agents; Child; Drug Resistance, Microbial; Drug Therapy, Combination; Ethambutol; Female; Humans; Immunocompromised Host; Infant; Isoniazid; Mycobacterium tuberculosis; Pregnancy; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis | 1993 |
Critical assessment of smear-positive pulmonary tuberculosis patients after chemotherapy under the district tuberculosis programme.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antitubercular Agents; Drug Administration Schedule; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Humans; India; Isoniazid; Male; Middle Aged; Patient Compliance; Pyrazinamide; Retrospective Studies; Rifampin; Sputum; Tuberculosis, Pulmonary | 1993 |
CDC recommends four-drug treatment of tuberculosis in multidrug-resistant era.
Topics: Adult; Centers for Disease Control and Prevention, U.S.; Child; Drug Therapy; Drug Therapy, Combination; Ethambutol; Female; Humans; Immunocompromised Host; Infant; Isoniazid; Pregnancy; Pregnancy Complications, Infectious; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis; Tuberculosis, Pulmonary; United States | 1993 |
Bactericidal action of pulsed exposure to rifampicin, ethambutol, isoniazid & pyrazinamide on Mycobacterium tuberculosis in vitro.
Topics: Antitubercular Agents; Drug Administration Schedule; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Time Factors | 1993 |
Initial therapy for tuberculosis in the era of multidrug resistance. Recommendations of the Advisory Council for the Elimination of Tuberculosis.
Topics: Adult; Antitubercular Agents; Child; Drug Resistance, Microbial; Drug Therapy, Combination; Ethambutol; Female; Humans; Immunocompromised Host; Infant; Isoniazid; Mycobacterium tuberculosis; Pregnancy; Pregnancy Complications, Infectious; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis | 1993 |
Antibiotic-resistant tuberculous choroiditis.
Topics: Aged; Anti-Bacterial Agents; Choroiditis; Drug Resistance, Microbial; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Mycobacterium tuberculosis; Prednisone; Pyrazinamide; Rifampin; Sputum; Tuberculosis, Ocular; Uveitis; Visual Acuity | 1993 |
Pelvic-peritoneal tuberculosis with elevated serum and peritoneal fluid Ca-125 levels. A report of two cases.
Topics: Adnexal Diseases; Adult; Antigens, Tumor-Associated, Carbohydrate; Ascitic Fluid; Diagnosis, Differential; Ethambutol; Female; Humans; Infertility, Female; Isoniazid; Menopause; Middle Aged; Peritonitis, Tuberculous; Pyrazinamide; Rifampin; Tuberculosis, Female Genital; Uterine Diseases | 1993 |
[Tuberculosis treatment in 1992].
Topics: Anti-Bacterial Agents; Drug Administration Schedule; Drug Therapy, Combination; Humans; Isoniazid; Pyrazinamide; Rifampin; Tuberculosis | 1993 |
Bacteriological investigations for short-course chemotherapy under the tuberculosis programme in two districts of India.
Topics: Adolescent; Adult; Aged; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; Isoniazid; Middle Aged; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Sputum; Tuberculosis, Pulmonary | 1993 |
Optochiasmatic tuberculoma causing progressive visual failure: when has medical treatment failed?
Topics: Child, Preschool; Dexamethasone; Drug Therapy, Combination; Female; Humans; Isoniazid; Mental Disorders; Optic Chiasm; Optic Nerve Diseases; Pyrazinamide; Pyridoxine; Rifampin; Streptomycin; Tuberculoma, Intracranial; Vision Disorders | 1993 |
Increased insulin requirement in a patient with type 1 diabetes on rifampicin.
Topics: Blood Glucose; Diabetes Mellitus, Type 1; Drug Therapy, Combination; Female; Humans; Insulin; Isoniazid; Middle Aged; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 1993 |
Mycobacterial infections in renal allograft recipients.
Topics: Drug Therapy, Combination; Ethambutol; HIV Seropositivity; Humans; Immunosuppressive Agents; Isoniazid; Kidney Transplantation; Mycobacterium Infections; New York; Postoperative Complications; Pyrazinamide; Rifampin; Transplantation, Homologous | 1993 |
The high incidence of tuberculosis among renal transplant recipients in India.
Topics: Adult; Antitubercular Agents; Ethambutol; Female; Follow-Up Studies; Humans; Incidence; India; Isoniazid; Kidney Transplantation; Male; Pyrazinamide; Tuberculosis | 1996 |
In vitro protein binding characteristics of isoniazid, rifampicin, and pyrazinamide to whole plasma, albumin, and alpha-1-acid glycoprotein.
Topics: Aging; Blood Proteins; Humans; In Vitro Techniques; Isoniazid; Orosomucoid; Plasma; Protein Binding; Pyrazinamide; Rifampin; Serum Albumin | 1996 |
Management of primary chest wall tuberculosis.
Topics: Abscess; Adult; Antibiotics, Antitubercular; Antitubercular Agents; Combined Modality Therapy; Debridement; Diagnosis, Differential; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Retrospective Studies; Rifampin; Suppuration; Thoracic Diseases; Thoracic Neoplasms; Treatment Outcome; Tuberculosis | 1995 |
Early bactericidal activity of ethambutol, pyrazinamide and the fixed combination of isoniazid, rifampicin and pyrazinamide (Rifater) in patients with pulmonary tuberculosis.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Colony Count, Microbial; Dose-Response Relationship, Drug; Drug Combinations; Drug Therapy, Combination; Humans; Isoniazid; Middle Aged; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; South Africa; Sputum; Tuberculosis, Pulmonary | 1996 |
[Primary tuberculosis of the oral cavity].
Topics: Antibiotics, Antitubercular; Antitubercular Agents; Drug Therapy, Combination; Female; Humans; Isoniazid; Middle Aged; Mouth Mucosa; Mycobacterium tuberculosis; Pyrazinamide; Radiography, Panoramic; Rifampin; Time Factors; Tooth Extraction; Tuberculosis, Oral | 1996 |
Abdominal tuberculosis in children: review of 26 cases.
Topics: Adolescent; Anti-Bacterial Agents; Antitubercular Agents; California; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Infant; Isoniazid; Male; Peritonitis, Tuberculous; Pyrazinamide; Retrospective Studies; Rifampin; Tuberculosis, Gastrointestinal | 1996 |
Hepatotoxic effects of tuberculosis therapy. A practical approach to a tricky management problem.
Topics: Antibiotics, Antitubercular; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Humans; Isoniazid; Liver; Liver Diseases; Pyrazinamide; Rifampin; Risk Factors; Tuberculosis | 1996 |
Total hip arthroplasty complicated by tuberculous infection.
Topics: Aged; Anti-Bacterial Agents; Drug Therapy, Combination; Ethambutol; Female; Hip Joint; Hip Prosthesis; Humans; Isoniazid; Mycobacterium tuberculosis; Prosthesis Failure; Prosthesis-Related Infections; Pyrazinamide; Radiography; Range of Motion, Articular; Reoperation; Rifampin; Tuberculosis, Osteoarticular | 1996 |
[Pleural tuberculosis with negative ADA].
Topics: Adenosine Deaminase; Adolescent; Antibiotics, Antitubercular; Antitubercular Agents; Clinical Enzyme Tests; Diagnosis, Differential; Drug Therapy, Combination; Female; Humans; Isoniazid; Pyrazinamide; Radiography, Thoracic; Rifampin; Tuberculosis, Pleural | 1996 |
Whither the roles of rifater and rifamate?
Topics: Antitubercular Agents; Drug Combinations; Humans; Isoniazid; Pyrazinamide; Rifampin; Trimethoprim; Tuberculosis | 1996 |
Effect of antituberculous drugs, isoniazid, pyrazinamide and rifampicin, on chemiluminescence of the human polymorphonuclear leukocytes.
Topics: Antitubercular Agents; Humans; Isoniazid; Luminescent Measurements; Neutrophils; Pyrazinamide; Reactive Oxygen Species; Rifampin | 1995 |
Clinical manifestation and outcome of tuberculosis in children with acquired immunodeficiency syndrome.
Topics: Acquired Immunodeficiency Syndrome; Adolescent; AIDS-Related Opportunistic Infections; Antibiotics, Antitubercular; Antitubercular Agents; Capreomycin; Child; Child, Preschool; Ethambutol; Female; Humans; Infant; Isoniazid; Male; Microbial Sensitivity Tests; Pyrazinamide; Rifampin; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 1996 |
Short-course therapy of pulmonary tuberculosis: doctor's compliance.
Topics: Adult; Alcoholism; Ambulatory Care; Antitubercular Agents; Clinical Competence; Drug Combinations; Family Practice; Female; Follow-Up Studies; Humans; Isoniazid; Male; Middle Aged; Prospective Studies; Pyrazinamide; Rifampin; Switzerland; Tuberculosis, Pulmonary | 1996 |
Drug diffusion through cystic fibrotic mucus: steady-state permeation, rheologic properties, and glycoprotein morphology.
Topics: Aminosalicylic Acid; Animals; Antitubercular Agents; Bronchi; Cystic Fibrosis; Diffusion; Glycoproteins; Humans; Isoniazid; Microscopy, Electron; Mucus; Permeability; Pyrazinamide; Rheology; Solutions; Swine | 1996 |
Liver injury during antituberculosis treatment: an 11-year study.
Topics: Adolescent; Adult; Aged; Alcohol Drinking; Antitubercular Agents; Aspartate Aminotransferases; Bilirubin; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Infant; Isoniazid; Jaundice; Liver Cirrhosis, Alcoholic; Male; Middle Aged; Pyrazinamide; Retrospective Studies; Rifampin | 1996 |
Intramedullary tuberculoma of the spinal cord with syringomyelia.
Topics: Adult; Antitubercular Agents; Drug Therapy, Combination; Follow-Up Studies; Humans; Isoniazid; Magnetic Resonance Imaging; Male; Pyrazinamide; Streptomycin; Syringomyelia; Treatment Outcome; Tuberculoma; Tuberculosis, Spinal | 1996 |
The duration of excretion of viable bacilli in elderly patients on treatment for cavitating pulmonary tuberculosis.
Topics: Aged; Antitubercular Agents; Black People; Ethambutol; Female; Humans; Isoniazid; Male; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Sputum; Time Factors; Tuberculosis, Pulmonary | 1996 |
Oral tuberculosis following autologous bone marrow transplantation for Hodgkin's disease with interleukin-2 and alpha-interferon immunotherapy.
Topics: Adjuvants, Immunologic; Adult; Anti-Bacterial Agents; Antitubercular Agents; Bone Marrow Transplantation; Combined Modality Therapy; Disease Susceptibility; Drug Therapy, Combination; Fistula; Hodgkin Disease; Humans; Immunocompromised Host; Interferon-alpha; Interleukin-2; Isoniazid; Male; Opportunistic Infections; Oral Ulcer; Pyrazinamide; Recombinant Proteins; Rifampin; Risk Factors; Transplantation Conditioning; Transplantation, Autologous; Tuberculosis, Oral | 1996 |
Preventive chemotherapy of tuberculosis in Cornell model mice with combinations of rifampin, isoniazid, and pyrazinamide.
Topics: Animals; Antitubercular Agents; Colony Count, Microbial; Culture Media; Drug Combinations; Drug Interactions; Isoniazid; Lung; Mice; Mice, Inbred BALB C; Pyrazinamide; Rats; Rifampin; Spleen; Tuberculosis | 1996 |
Human immunodeficiency virus infection in children with tuberculosis in Santo Domingo, Dominican Republic: prevalence, clinical findings, and response to antituberculosis treatment.
Topics: AIDS Serodiagnosis; Antibiotics, Antitubercular; Antitubercular Agents; Child, Preschool; Dominican Republic; Female; HIV Infections; HIV Seroprevalence; Humans; Infant; Isoniazid; Male; Prevalence; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Pulmonary | 1996 |
Focal tuberculosis of the liver with local hemorrhage in a patient with acquired immunodeficiency syndrome.
Topics: Acquired Immunodeficiency Syndrome; Adult; Ethambutol; Granuloma; Histocytochemistry; Homosexuality, Male; Humans; Isoniazid; Liver; Male; Mycobacterium; Pyrazinamide; Rifampin; Tuberculosis | 1996 |
The management of mycobacterial infections in HIV seropositive individuals. Jefferiss Wing Therapeutics and Protocols Group.
Topics: Adrenal Cortex Hormones; Amikacin; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotics, Antitubercular; Antitubercular Agents; Ciprofloxacin; Clarithromycin; Clofazimine; Drug Therapy, Combination; Ethambutol; HIV Infections; Humans; Isoniazid; Mycobacterium avium-intracellulare Infection; Mycobacterium Infections; Nontuberculous Mycobacteria; Practice Guidelines as Topic; Pyrazinamide; Pyridoxine; Radiography; Rifabutin; Rifampin; Tuberculosis, Meningeal; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 1996 |
Simultaneous determination of rifampicin, isoniazid and pyrazinamid by high performance thin layer chromatography.
Topics: Antitubercular Agents; Chromatography, Thin Layer; Drug Combinations; Isoniazid; Pyrazinamide; Reproducibility of Results; Rifampin; Sensitivity and Specificity; Tablets | 1996 |
Risk factors for side-effects of isoniazid, rifampin and pyrazinamide in patients hospitalized for pulmonary tuberculosis.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antitubercular Agents; Arthralgia; Child; Child, Preschool; Exanthema; Female; Hepatitis; Hospitalization; Humans; Incidence; Infant; Isoniazid; Liver; Logistic Models; Male; Middle Aged; Multivariate Analysis; Pyrazinamide; Retrospective Studies; Rifampin; Risk Factors; Treatment Outcome; Tuberculosis, Pulmonary | 1996 |
Multiple small bowel perforations in a patient on treatment of tuberculosis.
Topics: Adult; Antitubercular Agents; Drug Combinations; Female; Humans; Intestinal Perforation; Isoniazid; Pyrazinamide; Rifampin; Tuberculosis, Gastrointestinal; Tuberculosis, Pulmonary | 1996 |
Concurrent mucosal leishmaniasis and pulmonary tuberculosis.
Topics: Animals; Antibiotics, Antitubercular; Antitubercular Agents; Contraindications; Drug Therapy, Combination; Humans; Immunity, Cellular; Isoniazid; Leishmania; Leishmaniasis, Mucocutaneous; Male; Meglumine; Meglumine Antimoniate; Middle Aged; Organometallic Compounds; Pyrazinamide; Rifampin; Sputum; Streptomycin; Tuberculosis, Pulmonary | 1996 |
Disseminated infection due to multidrug-resistant Mycobacterium bovis in a patient who was seropositive for human immunodeficiency virus.
Topics: Antibiotics, Antitubercular; Antitubercular Agents; DNA Fingerprinting; DNA, Bacterial; Drug Resistance, Multiple; Ethambutol; HIV Infections; Humans; Isoniazid; Male; Microbial Sensitivity Tests; Middle Aged; Mycobacterium bovis; Mycobacterium Infections; Pyrazinamide; Rifampin | 1996 |
The 5-year outcome of multidrug resistant tuberculosis patients in the Cape Province of South Africa.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Female; Humans; Isoniazid; Male; Middle Aged; Mycobacterium tuberculosis; Outcome Assessment, Health Care; Pyrazinamide; Retrospective Studies; Rifampin; South Africa; Surveys and Questionnaires; Time Factors; Tuberculosis, Multidrug-Resistant | 1996 |
Four-drug initial therapy for TB is standard treatment.
Topics: Aminosalicylic Acid; Drug Therapy, Combination; Humans; Isoniazid; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis | 1996 |
Unusual presentation of intra-abdominal tuberculosis.
Topics: Antitubercular Agents; Child; Diagnosis, Differential; Ethambutol; Female; Humans; Isoniazid; Mycobacterium tuberculosis; Peritonitis, Tuberculous; Pyrazinamide; Rifampin; Tuberculosis, Gastrointestinal | 1996 |
Tuberculosis control programme guidelines--treatment regimens.
Topics: Antitubercular Agents; Body Weight; Dose-Response Relationship, Drug; Drug Combinations; Ethambutol; Humans; Isoniazid; Optic Neuritis; Practice Guidelines as Topic; Pyrazinamide; Rifampin; South Africa; Streptomycin; Tuberculosis | 1996 |
Tuberculosis and renal transplantation.
Topics: Adult; Antitubercular Agents; Drug Therapy, Combination; Ethambutol; Follow-Up Studies; Humans; Isoniazid; Kidney Transplantation; Male; Postoperative Complications; Pyrazinamide; Retrospective Studies; Rifampin; Time Factors; Tuberculosis | 1996 |
Tuberculous perianal ulcers.
Topics: Adult; Antibiotics, Antitubercular; Antitubercular Agents; Ethambutol; Fissure in Ano; Humans; Isoniazid; Male; Pyrazinamide; Rifampin; Tuberculosis, Gastrointestinal | 1996 |
Grand rounds--Hammersmith Hospital. Persistent fever in pulmonary tuberculosis.
Topics: Antitubercular Agents; Chronic Disease; Drug Resistance; Fever; Humans; Intestinal Absorption; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 1996 |
Changes in the size of adrenal glands in acute pulmonary tuberculosis with therapy.
Topics: Adolescent; Adrenal Glands; Adult; Antibiotics, Antitubercular; Antitubercular Agents; Female; Humans; Isoniazid; Male; Middle Aged; Prospective Studies; Pyrazinamide; Rifampin; Streptomycin; Tomography, X-Ray Computed; Tuberculosis, Pulmonary | 1996 |
[Severe hepatotoxicity of tuberculostatic agents. Increase in the incidence].
Topics: Acute Disease; Adult; Antibiotics, Antitubercular; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Female; Hepatic Encephalopathy; Humans; Isoniazid; Liver; Liver Failure; Liver Transplantation; Male; Middle Aged; Pyrazinamide; Rifampin | 1996 |
[Tuberculosis of the middle ear: a rare extrapulmonary manifestation].
Topics: Antibiotics, Antitubercular; Antitubercular Agents; Diagnosis, Differential; Ear Diseases; Ear, Middle; Female; Humans; Isoniazid; Middle Aged; Pyrazinamide; Rifampin; Tuberculosis; Tuberculosis, Pulmonary | 1996 |
Esophagomediastinal fistula as a complication of tuberculous mediastinal lymphadenitis.
Topics: Adult; Antibiotics, Antitubercular; Esophageal Fistula; Ethambutol; Female; Fistula; Humans; Isoniazid; Mediastinal Diseases; Pyrazinamide; Radiography, Thoracic; Rifampin; Tomography, X-Ray Computed; Tuberculosis, Lymph Node | 1996 |
Tuberculous meningitis.
Topics: Antitubercular Agents; Humans; Isoniazid; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Meningeal | 1997 |
Initial screening for antituberculous drug resistance at an inpatient facility in Leon, Nicaragua.
Topics: Adult; Antitubercular Agents; Cross-Sectional Studies; Drug Resistance, Multiple; Female; Humans; Isoniazid; Male; Microbial Sensitivity Tests; Middle Aged; Mycobacterium tuberculosis; Nicaragua; Prevalence; Pyrazinamide; Radiometry; Rifampin; Sputum; Streptomycin; Tuberculosis, Multidrug-Resistant | 1997 |
[Osteoarticular tuberculosis during infancy: the reality in our environment].
Topics: Antitubercular Agents; Child, Preschool; Female; Femur; Humans; Infant; Isoniazid; Male; Pyrazinamide; Radiography; Rifampin; Tuberculosis, Osteoarticular | 1997 |
Vulvovaginal tuberculosis: a case report.
Topics: Aged; Anti-Bacterial Agents; Antitubercular Agents; Drug Therapy, Combination; Ethambutol; Female; HIV Seronegativity; Humans; Isoniazid; Pyrazinamide; Rifampin; Tuberculosis, Female Genital; Vulvovaginitis | 1997 |
Pancreatic insufficiency due to antituberculous therapy.
Topics: Antitubercular Agents; Chronic Disease; Drug Hypersensitivity; Drug Therapy, Combination; Ethambutol; Exocrine Pancreatic Insufficiency; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin | 1997 |
[Oral desensitization to antitubercular agents].
Topics: Administration, Oral; Adult; Antitubercular Agents; Desensitization, Immunologic; Drug Combinations; Female; Humans; Isoniazid; Pyrazinamide; Rifampin | 1997 |
beta-Galactosidase reporter system in mycobacteria and its application in rapid antimycobacterial drug screening.
Topics: Anti-Bacterial Agents; Antitubercular Agents; beta-Galactosidase; Escherichia coli; Genes, Reporter; Isoniazid; Kinetics; Microbial Sensitivity Tests; Mycobacterium; Ofloxacin; Plasmids; Pyrazinamide; Recombinant Proteins; Rifampin; Streptomycin | 1997 |
[Liver injury under tuberculostatic treatment].
Topics: Aged; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Drug Combinations; Female; Humans; Isoniazid; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 1997 |
Resolution of a brainstem abscess through antituberculous therapy.
Topics: Adult; Antitubercular Agents; Brain Abscess; Brain Stem; Humans; Isoniazid; Magnetic Resonance Imaging; Male; Pyrazinamide; Rifampin | 1997 |
Pyrazinamide-induced granulomatous hepatitis.
Topics: Antitubercular Agents; Biopsy; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Granuloma; Humans; Isoniazid; Liver; Liver Function Tests; Male; Middle Aged; Pyrazinamide; Tuberculosis, Pulmonary | 1997 |
Reduced plasma concentrations of antituberculosis drugs in patients with HIV infection.
Topics: Adult; Aged; Antitubercular Agents; Case-Control Studies; Diarrhea; Ethambutol; Female; HIV Infections; HIV Seropositivity; Humans; Intestinal Absorption; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin | 1997 |
[The results of retreatment of pulmonary tuberculosis using a short 6-month protocol 1985-1991 in the pneumo-phthisiology department of the Point G hospital in Bamako].
Topics: Adolescent; Adult; Age Factors; Antibiotics, Antitubercular; Antitubercular Agents; Child; Drug Combinations; Female; Humans; Isoniazid; Male; Mali; Middle Aged; Patient Compliance; Pyrazinamide; Recurrence; Retreatment; Retrospective Studies; Rifampin; Sex Factors; Sputum; Streptomycin; Thioacetazone; Treatment Outcome; Tuberculosis, Pulmonary; World Health Organization | 1997 |
Tuberculosis of the ankle in childhood: clinical, roentgenographic and computed tomography findings.
Topics: Ankle Joint; Arthritis; Biopsy; Child; Drug Therapy, Combination; Female; Humans; Infant; Isoniazid; Male; Osteomyelitis; Pyrazinamide; Radiography; Rifampin; Tomography, Emission-Computed; Tuberculosis, Osteoarticular | 1997 |
Autoimmune haemolytic anaemia responding to anti-tuberculous treatment.
Topics: Adult; Anemia, Hemolytic; Antitubercular Agents; Autoimmune Diseases; Biopsy; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Male; Pyrazinamide; Rifampin; Tuberculosis, Lymph Node | 1997 |
Problems of diagnosis and treatment of tuberculosis following renal transplantation.
Topics: Adolescent; Adult; Antitubercular Agents; Bronchoalveolar Lavage Fluid; Drug Therapy, Combination; Ethambutol; Female; Humans; Immunosuppressive Agents; Isoniazid; Kidney Transplantation; Male; Middle Aged; Pakistan; Postoperative Complications; Pyrazinamide; Retrospective Studies; Sputum; Time Factors; Tuberculosis, Pulmonary | 1997 |
[Pulmonary tuberculosis caused by Mycobacterium bovis with primary resistance to Isoniazide and pyrazinamide].
Topics: Adult; Antitubercular Agents; Humans; Isoniazid; Male; Mycobacterium bovis; Pyrazinamide; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 1997 |
[Isolation obligation and therapy in tuberculosis].
Topics: Antitubercular Agents; Bronchoalveolar Lavage Fluid; Female; Humans; Isoniazid; Mycobacterium tuberculosis; Patient Isolation; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 1997 |
[Effects of intermittent short-course chemotherapy under full-course supervision on the treatment of smear positive pulmonary tuberculosis].
Topics: Antitubercular Agents; Drug Therapy, Combination; Ethambutol; Follow-Up Studies; Humans; Isoniazid; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Pulmonary | 1996 |
[CT scanning and treatment of intracranial tuberculoma].
Topics: Adolescent; Animals; Antitubercular Agents; Child; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Parietal Lobe; Pyrazinamide; Rabbits; Retrospective Studies; Rifampin; Streptomycin; Tomography, X-Ray Computed; Tuberculoma, Intracranial | 1996 |
[A severe form of urinary tuberculosis in children].
Topics: Adolescent; Antitubercular Agents; Atrophy; Bacteriuria; BCG Vaccine; Child; Cystitis; Hematuria; Humans; Isoniazid; Male; Mycobacterium tuberculosis; Nephrectomy; Pyrazinamide; Rifampin; Sclerosis; Tuberculosis, Pulmonary; Tuberculosis, Renal; Tuberculosis, Urogenital; Ureter; Urinary Bladder; Urinary Bladder Diseases | 1997 |
Short-course chemoprophylaxis evaluated in gold miners with chronic silicosis.
Topics: Antitubercular Agents; Gold; Humans; Isoniazid; Mining; Patient Compliance; Pyrazinamide; Rifampin; Silicosis; Treatment Outcome; Tuberculosis | 1997 |
Unusual miliary tuberculosis presenting with generalized lymphadenopathy and abdominal involvement.
Topics: Adult; Antitubercular Agents; Biopsy; Diagnosis, Differential; Drug Therapy, Combination; Ethambutol; Follow-Up Studies; Humans; Isoniazid; Lymph Nodes; Lymphatic Diseases; Male; Neck; Pleural Effusion; Prednisolone; Pyrazinamide; Rifampin; Sputum; Tomography, X-Ray Computed; Tuberculosis, Gastrointestinal; Tuberculosis, Miliary | 1997 |
[Reasons for chronic expectoration--case reports].
Topics: Adult; Aged; Antitubercular Agents; Capreomycin; Cycloserine; Drug Resistance, Microbial; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Patient Compliance; Pyrazinamide; Rifampin; Secondary Prevention; Sputum; Streptomycin; Treatment Failure; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 1997 |
[Surgical treatment of patients with multi-resistant pulmonary tuberculosis--case reports].
Topics: Adult; Antitubercular Agents; Bronchial Fistula; Drug Therapy, Combination; Ethambutol; Fatal Outcome; Humans; Isoniazid; Male; Middle Aged; Pleural Diseases; Pneumonectomy; Pyrazinamide; Rifampin; Sputum; Streptomycin; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 1997 |
[A case of multiple intracranial tuberculoma diagnosed by open brain biopsy].
Topics: Antitubercular Agents; Biopsy; Brain; Ethambutol; Humans; Immunocompromised Host; Isoniazid; Male; Middle Aged; Mycobacterium tuberculosis; Pyrazinamide; Streptomycin; Tuberculoma, Intracranial | 1997 |
[Tuberculosis in hemodialysis].
Topics: Adolescent; Adult; Antibiotics, Antitubercular; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Renal Dialysis; Retrospective Studies; Rifampin; Tuberculosis | 1997 |
Risk factors for hepatotoxicity induced by antituberculosis drugs.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Child; Ethambutol; Female; Humans; Isoniazid; Logistic Models; Male; Middle Aged; Pyrazinamide; Retrospective Studies; Rifampin; Risk Factors; Streptomycin | 1997 |
[Thrombocytopenia following a re-introduction of rifampicin in a daily treatment. Apropos of a case].
Topics: Adult; Antibiotics, Antitubercular; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Drug Administration Schedule; Drug Hypersensitivity; Ethambutol; Humans; Isoniazid; Male; Middle Aged; Purpura; Pyrazinamide; Rifampin; Streptomycin; Thrombocytopenia; Tuberculosis, Pulmonary | 1995 |
[Isolated colonic tuberculosis].
Topics: Aged; Antibiotics, Antitubercular; Antitubercular Agents; Colonic Diseases; Colonoscopy; Female; Humans; Isoniazid; Pyrazinamide; Rifampin; Tuberculosis, Gastrointestinal | 1997 |
[Urogenital tuberculosis. Apropos of 40 cases].
Topics: Adolescent; Adult; Aged; Antibiotics, Antitubercular; Antitubercular Agents; Biopsy; Combined Modality Therapy; Constriction, Pathologic; Cystitis; Female; Humans; Isoniazid; Male; Middle Aged; Mycobacterium tuberculosis; Nephrectomy; Prostatic Diseases; Pyrazinamide; Rifampin; Stents; Tuberculosis, Male Genital; Tuberculosis, Renal; Tuberculosis, Spinal; Tuberculosis, Urogenital; Ureteral Diseases; Urinary Bladder Diseases; Urography | 1997 |
Two excellent management tools for national tuberculosis programmes: history of prior treatment and sputum status at two months.
Topics: Antitubercular Agents; Drug Administration Schedule; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Medical Records; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Sputum; Streptomycin; Tuberculosis, Pulmonary | 1998 |
Physician compliance with national tuberculosis treatment guidelines: a university hospital study.
Topics: Antitubercular Agents; Cerebrospinal Fluid; Drug Administration Schedule; Drug Therapy, Combination; Ethambutol; Hospitals, University; Humans; Isoniazid; Mycobacterium tuberculosis; Pakistan; Physicians; Practice Guidelines as Topic; Pyrazinamide; Rifampin; Sputum; Surveys and Questionnaires; Tuberculosis; World Health Organization | 1998 |
How drug resistance emerges as a result of poor compliance during short course chemotherapy for tuberculosis.
Topics: AIDS-Related Opportunistic Infections; Antibiotics, Antitubercular; Antitubercular Agents; Drug Administration Schedule; Drug Resistance, Microbial; Ethambutol; HIV Seropositivity; Humans; Isoniazid; Mutation; Mycobacterium tuberculosis; Patient Compliance; Pyrazinamide; Recurrence; Rifampin; Streptomycin; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 1998 |
Should we take a history of prior treatment, and check sputum status at 2-3 months when treating patients for tuberculosis?
Topics: Adult; Ambulatory Care; Antibiotics, Antitubercular; Antitubercular Agents; Cohort Studies; Confidence Intervals; Drug Administration Schedule; Female; Follow-Up Studies; Forecasting; Humans; Isoniazid; Male; Medical History Taking; Predictive Value of Tests; Pyrazinamide; Recurrence; Retreatment; Rifampin; Risk Factors; Safety; Sensitivity and Specificity; South Africa; Sputum; Streptomycin; Treatment Failure; Tuberculosis, Pulmonary | 1998 |
Epidemiology of drug-resistant tuberculosis in New Jersey from 1991 to 1995.
Topics: Adult; Age Distribution; Aged; Antitubercular Agents; Confidence Intervals; Ethambutol; Female; Humans; Incidence; Isoniazid; Logistic Models; Male; Microbial Sensitivity Tests; Middle Aged; Mycobacterium tuberculosis; New Jersey; Odds Ratio; Population Surveillance; Pyrazinamide; Rifampin; Risk Factors; Sex Distribution; Streptomycin; Tuberculosis, Multidrug-Resistant | 1998 |
Drug resistant tuberculosis in prisons in Azerbaijan: case study.
Topics: Antibiotics, Antitubercular; Antitubercular Agents; Azerbaijan; Humans; Isoniazid; Mycobacterium tuberculosis; Prisoners; Pyrazinamide; Rifampin; Sputum; Streptomycin; Tuberculosis, Multidrug-Resistant | 1998 |
Tuberculous Addison's disease: lack of normalization of adrenocortical function after anti-tuberculous chemotherapy.
Topics: Addison Disease; Adrenal Cortex; Adrenal Cortex Function Tests; Adrenal Gland Diseases; Adrenocorticotropic Hormone; Adult; Aldosterone; Anti-Inflammatory Agents; Antitubercular Agents; Drug Therapy, Combination; Fludrocortisone; Humans; Hydrocortisone; Isoniazid; Male; Middle Aged; Prednisolone; Prospective Studies; Pyrazinamide; Rifampin; Tuberculosis, Endocrine | 1998 |
[Functional impotence of the lower limb in an infant].
Topics: Abscess; Antitubercular Agents; Drug Therapy, Combination; Femur; Humans; Infant; Isoniazid; Male; Pyrazinamide; Radiography; Tuberculosis, Osteoarticular | 1997 |
Short-course chemotherapy for isoniazid-resistant pulmonary tuberculosis.
Topics: Antitubercular Agents; Drug Administration Schedule; Drug Resistance, Microbial; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Retrospective Studies; Rifampin; Tuberculosis, Pulmonary | 1998 |
Concomitant lichen scrofulosorum and erythema induratum.
Topics: Adult; Antibiotics, Antitubercular; Antitubercular Agents; Erythema Induratum; Female; Humans; Isoniazid; Mycobacterium tuberculosis; Polymerase Chain Reaction; Pyrazinamide; Rifampin; Skin; Tuberculin Test; Tuberculosis, Cutaneous | 1998 |
Low serum antimycobacterial drug levels in non-HIV-infected tuberculosis patients.
Topics: Adult; Aged; Antibiotics, Antitubercular; Antitubercular Agents; Drug Monitoring; Drug Therapy, Combination; Female; HIV Infections; Humans; Isoniazid; Male; Middle Aged; Patient Compliance; Pyrazinamide; Rifampin; Treatment Failure; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 1998 |
[Analysis of short-term effects of short-course intermittent chemotherapies of the World Bank Loaned Project].
Topics: Antibiotics, Antitubercular; Antitubercular Agents; Drug Therapy, Combination; Humans; Isoniazid; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Sputum; Streptomycin; Tuberculosis, Pulmonary | 1996 |
Isoniazid versus rifampicin and pyrazinamide for prevention of tuberculosis in HIV-1 infection.
Topics: AIDS-Related Opportunistic Infections; Antitubercular Agents; Developing Countries; Drug Therapy, Combination; HIV-1; Humans; Isoniazid; Pyrazinamide; Rifampin; Tuberculosis | 1998 |
Central nervous system tuberculosis after resolution of miliary tuberculosis.
Topics: Antitubercular Agents; Central Nervous System Infections; Dexamethasone; Drug Therapy, Combination; Ethionamide; Glucocorticoids; Humans; Immunocompetence; Infant; Isoniazid; Male; Prednisolone; Pyrazinamide; Rifampin; Streptomycin; Treatment Failure; Tuberculoma; Tuberculosis, Meningeal; Tuberculosis, Miliary; Tuberculosis, Multidrug-Resistant | 1998 |
[Recurrent tuberculosis in a psychiatric hospital, recurrent outbreaks during 1987-1996].
Topics: Antitubercular Agents; Disease Outbreaks; Drug Therapy, Combination; Follow-Up Studies; Hospitals, Psychiatric; Humans; Incidence; Isoniazid; Israel; Pyrazinamide; Recurrence; Rifampin; Tuberculosis, Pulmonary | 1998 |
[Eruption after the 1st dose of standard antitubercular chemotherapy. Thoughts on pyrazinamide].
Topics: Aged; Antitubercular Agents; Child; Drug Combinations; Drug Eruptions; Ethambutol; Exanthema; Female; Humans; Isoniazid; Male; Middle Aged; Pruritus; Pyrazinamide; Recurrence; Rifampin; Tuberculosis, Pulmonary | 1998 |
[Resistance and multiresistance to antitubercular drugs in Argentina and in other Latin American countries].
Topics: Acquired Immunodeficiency Syndrome; Antitubercular Agents; Argentina; Drug Resistance, Microbial; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Latin America; Mycobacterium tuberculosis; Pyrazinamide; Streptomycin; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 1998 |
Does AIDS impair the absorption of antituberculosis agents?
Topics: Absorption; Acquired Immunodeficiency Syndrome; Adolescent; Adult; Antitubercular Agents; Biological Availability; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Tuberculosis | 1998 |
Sequential evaluation of serum adenosine deaminase in patients treated for tuberculosis.
Topics: Adenosine Deaminase; Adolescent; Adult; Antitubercular Agents; Biomarkers; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Pleural; Tuberculosis, Pulmonary | 1998 |
Phenomenon of rifampicin-induced discolouration of body fluids.
Topics: Aged; Antibiotics, Antitubercular; Antitubercular Agents; Chromogenic Compounds; Drug Interactions; Humans; Isoniazid; Male; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 1993 |
Peptide-specific T cell response to Mycobacterium tuberculosis: clinical spectrum, compartmentalization, and effect of chemotherapy.
Topics: Adolescent; Adult; Antigens, Bacterial; Antitubercular Agents; Bacterial Proteins; BCG Vaccine; Cell Division; Cells, Cultured; Epitopes, T-Lymphocyte; Ethambutol; Female; Humans; Interferon-gamma; Interleukin-10; Isoniazid; Leukocytes, Mononuclear; Lipoproteins; Male; Middle Aged; Mycobacterium tuberculosis; Peptides; Pleural Effusion; Pyrazinamide; Rifampin; T-Lymphocytes; Tuberculin; Tuberculosis | 1998 |
Prevention of tuberculosis in HIV-1.
Topics: AIDS-Related Opportunistic Infections; Antitubercular Agents; Drug Resistance, Microbial; HIV-1; Humans; Isoniazid; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Tuberculosis | 1998 |
Intensive short course chemotherapy in the management of tuberculous meningitis.
Topics: Antibiotics, Antitubercular; Antitubercular Agents; Child; Child, Preschool; Drug Therapy, Combination; Ethionamide; Humans; Infant; Isoniazid; Prospective Studies; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Meningeal | 1998 |
Primary tuberculous tracheitis.
Topics: Antitubercular Agents; Cough; Ethambutol; Female; Humans; Isoniazid; Middle Aged; Pyrazinamide; Respiratory Sounds; Rifampin; Tracheal Stenosis; Tracheitis; Tuberculosis, Pulmonary | 1998 |
Short-term tuberculosis prophylaxis is effective in persons with HIV.
Topics: AIDS-Related Opportunistic Infections; Antitubercular Agents; Humans; Isoniazid; Patient Compliance; Pyrazinamide; Randomized Controlled Trials as Topic; Rifampin; Tuberculosis | 1998 |
Chemotherapy and management of tuberculosis in the United Kingdom: recommendations 1998. Joint Tuberculosis Committee of the British Thoracic Society.
Topics: Adult; Antitubercular Agents; Child; Child, Preschool; Disease Notification; Drug Administration Schedule; Ethambutol; Female; Humans; Infant; Isoniazid; Male; Pregnancy; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 1998 |
Longitudinal trends in serum levels of mycobacterial secretory (30 kD) and cytoplasmic (65 kD) antigens during chemotherapy of pulmonary tuberculosis patients.
Topics: Antibodies, Bacterial; Antigens, Bacterial; Antitubercular Agents; Drug Therapy, Combination; Enzyme-Linked Immunosorbent Assay; Ethambutol; Humans; Isoniazid; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Time Factors; Treatment Outcome; Tuberculosis, Pulmonary | 1998 |
[Fulminant hepatitis in the course of antitubercular treatment (apropos of 2 cases)].
Topics: Adult; Anti-Bacterial Agents; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Ethambutol; Fatal Outcome; Female; HIV Infections; Humans; Isoniazid; Liver Function Tests; Pyrazinamide; Rifampin; Tuberculosis, Miliary; Tuberculosis, Pulmonary | 1995 |
Shock and cerebral infarct after rifampin re-exposure in a patient infected with human immunodeficiency virus.
Topics: Adult; Anaphylaxis; Antibiotics, Antitubercular; Antitubercular Agents; Cerebral Infarction; Drug Hypersensitivity; Drug Therapy, Combination; HIV Infections; Humans; Isoniazid; Male; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 1998 |
Short-course prophylaxis against tuberculosis in HIV-infected persons. A decision and cost-effectiveness analysis.
Topics: AIDS-Related Opportunistic Infections; Antibiotics, Antitubercular; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Cost-Benefit Analysis; Decision Trees; Drug Administration Schedule; Drug Therapy, Combination; Humans; Isoniazid; Pyrazinamide; Quality-Adjusted Life Years; Rifampin; Survival Rate; Tuberculosis | 1998 |
[Efficacy of a short 6 month therapeutic coursefor HIV infected tuberculosis patients in Abidjan, Côte d'Ivoire].
Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Antitubercular Agents; Cohort Studies; Cote d'Ivoire; Female; Humans; Isoniazid; Male; Middle Aged; Prospective Studies; Pyrazinamide; Rifampin; Tuberculosis | 1998 |
Subchronic toxicity of human immunodeficiency virus and tuberculosis combination therapies in B6C3F1 mice.
Topics: Animals; Anti-HIV Agents; Antibiotics, Antitubercular; Blood Platelets; Bone Marrow; Drug Interactions; Erythrocytes; Female; Hemoglobins; Isoniazid; Male; Mice; Pyrazinamide; Rifampin; Toxicity Tests; Zidovudine | 1998 |
Tuberculosis of the pyriform fossa--a rare entity.
Topics: Adult; Antitubercular Agents; Diagnosis, Differential; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Laryngoscopy; Male; Pharyngeal Diseases; Pharyngeal Neoplasms; Pyrazinamide; Radiography; Rifampin; Tuberculosis; Tuberculosis, Laryngeal; Tuberculosis, Pulmonary | 1998 |
[Hepatic tuberculosis: a case with pseudotumours form].
Topics: Adult; Antibiotics, Antitubercular; Antitubercular Agents; Drug Therapy, Combination; Ethambutol; Female; Follow-Up Studies; Humans; Isoniazid; Pyrazinamide; Rifampin; Time Factors; Tomography, X-Ray Computed; Tuberculosis, Hepatic | 1998 |
Management of presumed intraocular tuberculosis: possible role of the polymerase chain reaction.
Topics: Adolescent; Adult; Antibiotics, Antitubercular; Aqueous Humor; Child; DNA Primers; DNA, Bacterial; Female; Humans; Isoniazid; Male; Middle Aged; Mycobacterium tuberculosis; Polymerase Chain Reaction; Pyrazinamide; Rifampin; Tuberculin Test; Tuberculosis, Ocular; Uveitis | 1998 |
Brainstem tuberculoma mimicking glioma: the role of antituberculous drugs as a diagnostic tool.
Topics: Antitubercular Agents; Brain Neoplasms; Diagnosis, Differential; Female; Glioma; Humans; Isoniazid; Magnetic Resonance Imaging; Middle Aged; Pyrazinamide; Rifampin; Tuberculoma | 1999 |
Tuberculosis of the sternoclavicular joint. Report of two cases.
Topics: Adult; Drug Therapy, Combination; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Sternoclavicular Joint; Tomography, X-Ray Computed; Treatment Outcome; Tuberculin Test; Tuberculosis, Osteoarticular | 1998 |
Determination of rifampicin and its main metabolite in plasma and urine in presence of pyrazinamide and isoniazid by HPLC method.
Topics: Antibiotics, Antitubercular; Antitubercular Agents; Calibration; Chromatography, High Pressure Liquid; Humans; Hydrogen-Ion Concentration; Indicators and Reagents; Isoniazid; Pyrazinamide; Reproducibility of Results; Rifampin; Spectrophotometry, Ultraviolet | 1999 |
The management of pulmonary tuberculosis in adults notified in Scotland in 1993.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antitubercular Agents; Clinical Protocols; Disease Notification; Humans; Isoniazid; Middle Aged; Practice Patterns, Physicians'; Pyrazinamide; Rifampin; Scotland; Tuberculosis, Pulmonary | 1998 |
Therapeutic dilemma: crescentic mesangiocapillary glomerulonephritis type 1 in a patient on antituberculous therapy with rifampicin.
Topics: Aged; Antitubercular Agents; Clarithromycin; Female; Glomerulonephritis, Membranoproliferative; Humans; Isoniazid; Methylprednisolone; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Sputum; Tuberculosis, Pulmonary | 1999 |
Good news and not such good news.
Topics: Antitubercular Agents; Drug Combinations; Humans; Isoniazid; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 1999 |
Bioavailability of rifampicin, isoniazid and pyrazinamide in a triple drug formulation: comparison of plasma and urine kinetics.
Topics: Adult; Antitubercular Agents; Biological Availability; Cross-Over Studies; Drug Combinations; Humans; Isoniazid; Male; Pyrazinamide; Rifampin | 1999 |
The effect of hemodialysis on isoniazid, rifampin, pyrazinamide, and ethambutol.
Topics: Adult; Antibiotics, Antitubercular; Antitubercular Agents; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Renal Dialysis; Rifampin | 1999 |
Mycobacterium bovis BCG causing vertebral osteomyelitis (Pott's disease) following intravesical BCG therapy.
Topics: Administration, Intravesical; Aged; Antitubercular Agents; BCG Vaccine; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Male; Mycobacterium bovis; Osteomyelitis; Pyrazinamide; Rifampin; Tuberculosis, Spinal; Urinary Bladder Neoplasms | 1999 |
-Skin eruption after the first dose of antitubercular quadri-therapy: consideration of pyrazinamide-.
Topics: Antibiotics, Antitubercular; Antitubercular Agents; Child; Drug Combinations; Drug Eruptions; Ethambutol; Exanthema; Humans; Isoniazid; Male; Pyrazinamide; Recurrence; Rifampin; Tuberculosis, Pulmonary | 1998 |
[Six-months chemotherapy (2HRZS or E/4HRE) of new cases of pulmonary tuberculosis--six year experiences on its effectiveness, toxicity, and acceptability].
Topics: Adult; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Diabetes Complications; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Patient Acceptance of Health Care; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Pulmonary | 1999 |
Twice-weekly, directly observed treatment for HIV-infected and uninfected tuberculosis patients: cohort study in rural South Africa.
Topics: Adult; AIDS-Related Opportunistic Infections; Antitubercular Agents; Cohort Studies; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Mycobacterium tuberculosis; Predictive Value of Tests; Prospective Studies; Pyrazinamide; Rifampin; South Africa; Sputum; Treatment Outcome; Tuberculosis | 1999 |
[Efficacy of unfixed continuation phase short-course chemotherapy].
Topics: Adult; Antitubercular Agents; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Recurrence; Rifampin; Streptomycin; Tuberculosis, Pulmonary | 1997 |
Chemotherapy of tuberculosis in mice using single implants of isoniazid and pyrazinamide.
Topics: Administration, Oral; Analysis of Variance; Animals; Antitubercular Agents; Biocompatible Materials; Biological Availability; Delayed-Action Preparations; Disease Models, Animal; Drug Administration Schedule; Drug Implants; Isoniazid; Lactic Acid; Male; Mice; Mice, Inbred C57BL; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Pyrazinamide; Sensitivity and Specificity; Tuberculosis | 1999 |
The spectrum of mycobacterial disease in a Dublin teaching hospital.
Topics: Adult; Antitubercular Agents; Female; Hospitals, Teaching; Humans; Isoniazid; Lung Neoplasms; Male; Middle Aged; Mycobacterium tuberculosis; Northern Ireland; Pyrazinamide; Radiography, Thoracic; Treatment Outcome; Tuberculin Test; Tuberculosis, Pulmonary | 1999 |
Therapy of tuberculosis in mice by DNA vaccination.
Topics: Animals; Antigens, Bacterial; Antitubercular Agents; Bacterial Proteins; Chaperonin 60; Chaperonins; Combined Modality Therapy; Female; Interferon-gamma; Interleukin-12; Interleukin-4; Isoniazid; Mice; Mice, Inbred BALB C; Mycobacterium leprae; Mycobacterium tuberculosis; Plasmids; Pyrazinamide; T-Lymphocytes; Tuberculosis; Vaccines, DNA | 1999 |
Drug-resistant tuberculosis in the Philippines.
Topics: Antitubercular Agents; Drug Resistance, Multiple; Ethambutol; Female; Humans; Incidence; Isoniazid; Male; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Philippines; Pyrazinamide; Rifampin; Tuberculosis, Multidrug-Resistant | 1999 |
Four-month, four-drug preventive therapy for inactive pulmonary tuberculosis.
Topics: Adult; Aged; Antitubercular Agents; Cost-Benefit Analysis; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Emigration and Immigration; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Patient Compliance; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Pulmonary | 1999 |
Cutaneous tuberculosis: efficient therapeutic response in a case with multiple lesions.
Topics: Adult; Antibiotics, Antitubercular; Antitubercular Agents; Drug Therapy, Combination; Ethambutol; Female; Foot Dermatoses; Hand Dermatoses; Humans; Isoniazid; Pyrazinamide; Rifampin; Tuberculosis, Cutaneous | 1999 |
Reply: Treatment of tuberculosis in HIV-infected patients.
Topics: Antibiotics, Antitubercular; Antitubercular Agents; Drug Therapy, Combination; HIV Infections; Humans; Isoniazid; Pyrazinamide; Streptomycin; Tuberculosis | 1999 |
Reactivation of latent tuberculosis: variations on the Cornell murine model.
Topics: Animals; Antitubercular Agents; Dexamethasone; Disease Models, Animal; Genetic Variation; Glucocorticoids; Immunosuppression Therapy; Interferon-gamma; Isoniazid; Mice; Mice, Inbred C57BL; Mycobacterium tuberculosis; Neutralization Tests; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Pyrazinamide; Rats; Tuberculosis | 1999 |
Is the treatment of WHO category I tuberculosis with 2HRZE/6HE a defensible practice?
Topics: Antitubercular Agents; Developing Countries; Drug Resistance, Microbial; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Multidrug-Resistant; World Health Organization | 1999 |
Evaluation of rifapentine in long-term treatment regimens for tuberculosis in mice.
Topics: Animals; Antibiotics, Antitubercular; Antitubercular Agents; Disease Models, Animal; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Isoniazid; Mice; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Rifamycins; Tuberculosis | 1999 |
Relapse rates after short-course (6-month) treatment of tuberculosis in HIV-infected and uninfected persons.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; AIDS-Related Opportunistic Infections; Antitubercular Agents; Child; Child, Preschool; Cohort Studies; Ethambutol; Female; Follow-Up Studies; Humans; Infant; Isoniazid; Male; Middle Aged; Pyrazinamide; Recurrence; Rifampin; Time Factors; Tuberculosis | 1999 |
Pulmonary nodule mimicking lung cancer in a human immunodeficiency virus type-1 infected patient.
Topics: Acquired Immunodeficiency Syndrome; Adenocarcinoma; Adult; Antitubercular Agents; Diagnosis, Differential; Drug Therapy, Combination; Ethambutol; HIV-1; Humans; Isoniazid; Lung Neoplasms; Male; Pyrazinamide; Rifampin; Solitary Pulmonary Nodule; Tomography, X-Ray Computed | 1999 |
Evaluation of a bacteriophage-based assay (phage amplified biologically assay) as a rapid screen for resistance to isoniazid, ethambutol, streptomycin, pyrazinamide, and ciprofloxacin among clinical isolates of Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Ciprofloxacin; Drug Resistance, Microbial; Ethambutol; Evaluation Studies as Topic; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacteriophages; Mycobacterium tuberculosis; Phenotype; Pyrazinamide; Streptomycin; Tuberculosis | 1999 |
[Current aspects of spinal tuberculosis: apropos of 16 case reports].
Topics: Adult; Aged; Antibiotics, Antitubercular; Antitubercular Agents; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Magnetic Resonance Imaging; Male; Middle Aged; Pyrazinamide; Retrospective Studies; Rifampin; Tomography, X-Ray Computed; Tuberculosis, Spinal | 1999 |
Determination of rifampicin, isoniazid and pyrazinamide by high performance liquid chromatography after their simultaneous extraction from plasma.
Topics: Antitubercular Agents; Chromatography, High Pressure Liquid; Humans; Isoniazid; Pyrazinamide; Rifampin; Sensitivity and Specificity | 1999 |
The colorimetric analysis of anti-tuberculosis fixed-dose combination tablets and capsules.
Topics: Antitubercular Agents; Capsules; Chemistry, Pharmaceutical; Colorimetry; Drug Combinations; Ethambutol; Isoniazid; Pyrazinamide; Rifampin; Tablets | 1999 |
[Disseminated extrapulmonary tuberculosis with skin, lymph node and bone involvement].
Topics: Aged; Antibiotics, Antitubercular; Antitubercular Agents; Fibula; Follow-Up Studies; HIV Seronegativity; Humans; Isoniazid; Male; Osteomyelitis; Pyrazinamide; Rifampin; Time Factors; Tomography, X-Ray Computed; Tuberculosis, Cutaneous; Tuberculosis, Lymph Node; Tuberculosis, Osteoarticular | 1999 |
Chronic ulceration of the tongue and laryngitis: first clinical sign of asymptomatic pulmonary tuberculosis.
Topics: Adult; Antitubercular Agents; Drug Therapy, Combination; Humans; Isoniazid; Laryngitis; Male; Pyrazinamide; Rifampin; Tongue; Tuberculosis, Pulmonary; Ulcer | 1999 |
Mycobacterial infections in solid organ transplant recipients.
Topics: Adolescent; Adult; Antitubercular Agents; Drug Therapy, Combination; Ethambutol; Female; Follow-Up Studies; Humans; Isoniazid; Male; Mycobacterium Infections; Organ Transplantation; Postoperative Complications; Pyrazinamide; Retrospective Studies; Rifampin; Rural Population; Socioeconomic Factors; Time Factors; Turkey | 1999 |
Unusual clinical manifestation of tuberculosis in a renal transplant recipient.
Topics: Adult; Antitubercular Agents; Ethambutol; Fatal Outcome; Female; Humans; Isoniazid; Kidney Transplantation; Liver; Liver Function Tests; Postoperative Complications; Pyrazinamide; Rifampin; Tuberculin Test; Tuberculosis | 1999 |
Reply to Davis and colleagues: Twice weekly, directly observed treatment for HIV-infected and uninfected tuberculosis patients: cohort study in rural South Africa.
Topics: Antitubercular Agents; Drug Administration Schedule; Drug Resistance, Microbial; Drug Resistance, Multiple; Ethambutol; HIV Infections; Humans; Isoniazid; Pyrazinamide; Rifampin; South Africa; Tuberculosis, Pulmonary | 1999 |
Simultaneous determination of rifampicin, isoniazid and pyrazinamide in tablet preparations by multivariate spectrophotometric calibration.
Topics: Antitubercular Agents; Isoniazid; Multivariate Analysis; Pyrazinamide; Rifampin; Spectrophotometry; Tablets | 1999 |
Tuberculosis chemotherapy and sputum conversion among HIV-seropositive and HIV-seronegative patients in south-eastern Uganda.
Topics: Adolescent; Adult; AIDS-Related Opportunistic Infections; Antitubercular Agents; Drug Resistance; Drug Therapy, Combination; Female; HIV Seronegativity; HIV Seroprevalence; Humans; Isoniazid; Male; Middle Aged; Prospective Studies; Pyrazinamide; Rifampin; Sputum; Streptomycin; Survival Analysis; Treatment Outcome; Tuberculosis, Pulmonary; Uganda | 1999 |
Diagnosis and treatment of cervical tuberculous lymphadenitis.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Antitubercular Agents; Biopsy, Needle; Child; Child, Preschool; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Mycobacterium; Neck Dissection; Pyrazinamide; Retrospective Studies; Rifampin; Treatment Outcome; Tuberculosis, Lymph Node | 2000 |
Antituberculosis activity of once-weekly rifapentine-containing regimens in mice. Long-term effectiveness with 6- and 8-month treatment regimens.
Topics: Animals; Antibiotics, Antitubercular; Antitubercular Agents; Colony Count, Microbial; Drug Administration Schedule; Drug Resistance, Microbial; Drug Therapy, Combination; Ethambutol; Female; Isoniazid; Lung; Mice; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Spleen; Streptomycin; Tuberculosis | 2000 |
Pyrazinamide is not active against Mycobacterium tuberculosis residing in cultured human monocyte-derived macrophages.
Topics: Antitubercular Agents; Cells, Cultured; Humans; Isoniazid; Macrophages; Mycobacterium tuberculosis; Pyrazinamide; Pyrazines | 2000 |
Spinal intramedullary tuberculous lesion: medical management. Report of four cases.
Topics: Adolescent; Adult; Antibiotics, Antitubercular; Antitubercular Agents; Clinical Protocols; Female; Follow-Up Studies; Humans; Isoniazid; Magnetic Resonance Imaging; Male; Pyrazinamide; Rifampin; Spinal Cord Diseases; Streptomycin; Tuberculoma; Tuberculosis, Central Nervous System; Tuberculosis, Meningeal; Tuberculosis, Pulmonary | 2000 |
Kinetics of circulating antibodies, immune complex and specific antibody-secreting cells in tuberculosis patients during 6 months of antimicrobial therapy.
Topics: Adult; Aged; Anti-Bacterial Agents; Antibodies, Bacterial; Antibody-Producing Cells; Antigen-Antibody Complex; Antitubercular Agents; Drug Therapy, Combination; Enzyme-Linked Immunosorbent Assay; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Mycobacterium tuberculosis; Predictive Value of Tests; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Pulmonary | 2000 |
[Efficiency of shorter chemotherapy courses for intrathoracic tuberculosis in children].
Topics: Antibiotics, Antitubercular; Antitubercular Agents; Child; Child, Preschool; Drug Therapy, Combination; Humans; Isoniazid; Pyrazinamide; Retrospective Studies; Rifampin; Streptomycin; Time Factors; Treatment Outcome; Tuberculosis, Pleural; Tuberculosis, Pulmonary | 2000 |
[Intracranial tuberculomas developing during treatment of pulmonary tuberculosis: case report].
Topics: Adult; Antitubercular Agents; Humans; Isoniazid; Magnetic Resonance Imaging; Male; Pyrazinamide; Rifampin; Tomography, X-Ray Computed; Tuberculoma, Intracranial; Tuberculosis, Meningeal; Tuberculosis, Miliary; Tuberculosis, Pulmonary | 2000 |
Relation of leptin and tumor necrosis factor alpha to body weight changes in patients with pulmonary tuberculosis.
Topics: Adult; Antibiotics, Antitubercular; Antitubercular Agents; Body Mass Index; Body Weight; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Leptin; Male; Middle Aged; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary; Tumor Necrosis Factor-alpha | 1999 |
Lipid biochemistry takes a stand against tuberculosis.
Topics: Acetyltransferases; Antitubercular Agents; Bacterial Proteins; Drug Therapy, Combination; Fatty Acid Synthase, Type II; Fatty Acid Synthases; Humans; Isoniazid; Multienzyme Complexes; Prodrugs; Pyrazinamide; Tuberculosis, Pulmonary | 2000 |
The comparison of tuberculosis treatments: a short course therapy and the directly observed short course treatment (DOTS), East Java Province, Indonesia.
Topics: Antitubercular Agents; Drug Administration Schedule; Drug Therapy, Combination; Ethambutol; Humans; Indonesia; Isoniazid; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Pulmonary | 2000 |
Comparison of Mycobacterium tuberculosis susceptibility testing performed with BACTEC 460TB (Becton Dickinson) and MB/BacT (Organon Teknika) systems.
Topics: Antibiotics, Antitubercular; Antitubercular Agents; Carbon Dioxide; Ethambutol; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrazinamide; Reagent Kits, Diagnostic; Rifampin; Sensitivity and Specificity; Streptomycin; Time Factors | 2000 |
Evaluation of rifalazil in a combination treatment regimen as an alternative to isoniazid-rifampin therapy in a mouse tuberculosis model.
Topics: Animals; Antitubercular Agents; Colony-Forming Units Assay; Disease Models, Animal; Drug Therapy, Combination; Ethambutol; Female; Isoniazid; Mice; Pyrazinamide; Rifampin; Rifamycins; Tuberculosis | 2000 |
Second episode of tuberculosis in an HIV-infected child: relapse or reinfection?
Topics: AIDS-Related Opportunistic Infections; Amoxicillin-Potassium Clavulanate Combination; Antibiotics, Antitubercular; Antitubercular Agents; Child, Preschool; DNA, Bacterial; Drug Therapy, Combination; Ethionamide; HIV; HIV Infections; Humans; Isoniazid; Male; Mycobacterium tuberculosis; Polymorphism, Restriction Fragment Length; Pyrazinamide; Radiography, Thoracic; Rifampin; Secondary Prevention; South Africa; Tomography, X-Ray Computed; Tuberculin Test; Tuberculosis; Tuberculosis, Meningeal | 2000 |
Treatment of tuberculosis: a well-standardised protocol.
Topics: Adult; Child; Clinical Protocols; Ethambutol; France; Humans; Isoniazid; Pyrazinamide; Rifampin; Time Factors; Tuberculosis; United Kingdom; United States; World Health Organization | 2000 |
Chromosomal aberrations and micronuclei in lymphocytes of patients before and after exposure to anti-tuberculosis drugs.
Topics: Adolescent; Adult; Age Factors; Aged; Antibiotics, Antitubercular; Antitubercular Agents; Case-Control Studies; Cell Nucleus; Chromosome Aberrations; Ethambutol; Female; Humans; Isoniazid; Lymphocytes; Male; Micronuclei, Chromosome-Defective; Middle Aged; Pyrazinamide; Rifampin; Streptomycin | 2000 |
Tuberculous abscess of the graft in a renal transplant recipient after chronic rejection: case report.
Topics: Abscess; Adult; Antitubercular Agents; Chronic Disease; Drug Therapy, Combination; Ethambutol; Female; Graft Rejection; Humans; Isoniazid; Kidney Transplantation; Nephrectomy; Pyrazinamide; Reoperation; Rifampin; Tuberculosis | 2000 |
Tuberculosis after renal transplantation.
Topics: Adult; Antitubercular Agents; Drug Therapy, Combination; Ethambutol; Female; Follow-Up Studies; Humans; Incidence; India; Isoniazid; Kidney Transplantation; Living Donors; Male; Postoperative Complications; Pyrazinamide; Pyridoxine; Retrospective Studies; Rifampin; Time Factors; Tuberculosis; Tuberculosis, Pulmonary | 2000 |
Paradoxical worsening of tuberculosis after anti-TB therapy in a kidney transplant recipient.
Topics: Adult; Antitubercular Agents; Disease Progression; Drug Therapy, Combination; Ethambutol; Female; Humans; Immunosuppressive Agents; Isoniazid; Kidney Transplantation; Living Donors; Mycobacterium tuberculosis; Postoperative Complications; Pyrazinamide; Rifampin; Tomography, X-Ray Computed; Tuberculosis, Pulmonary | 2000 |
[The effectiveness of pyrazinamide-containing six-month short course chemotherapy].
Topics: Adult; Aged; Aged, 80 and over; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Diabetes Mellitus; Drug Therapy, Combination; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Recurrence; Rifampin; Risk Factors; Time Factors; Tuberculosis, Pulmonary | 2000 |
Atlantoaxial tuberculosis: three cases.
Topics: Adult; Aged; Antitubercular Agents; Atlanto-Axial Joint; Drug Therapy, Combination; Female; Humans; Immobilization; Isoniazid; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Streptomycin; Tomography, X-Ray Computed; Tuberculosis, Spinal | 2000 |
Surface-enhanced raman spectra of some anti-tubercle bacillus drugs.
Topics: Antitubercular Agents; Isoniazid; Niacinamide; Pyrazinamide; Spectrum Analysis, Raman | 2000 |
[Early anterolateral surgery for tuberculosis of the lower cervical spine with neurological complications in adult. Our experience in Gabon].
Topics: Adult; Antitubercular Agents; Cervical Vertebrae; Combined Modality Therapy; Debridement; Emergencies; Ethambutol; Follow-Up Studies; Gabon; Humans; Isoniazid; Kyphosis; Paraplegia; Physical Therapy Modalities; Pyrazinamide; Quadriplegia; Retrospective Studies; Rifampin; Treatment Outcome; Tuberculosis, Spinal | 2000 |
Contralateral pleural effusion during chemotherapy for tuberculous pleural effusion.
Topics: Adult; Antitubercular Agents; Drug Therapy, Combination; Female; Humans; Isoniazid; Pleural Effusion; Pyrazinamide; Radiography, Thoracic; Rifampin; Tuberculosis | 2000 |
A whole blood bactericidal assay for tuberculosis.
Topics: Anti-Infective Agents; Antitubercular Agents; Aza Compounds; Blood; Blood Bactericidal Activity; Culture Media; Ethambutol; Fluoroquinolones; Humans; Isoniazid; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Quinolines; Rifampin | 2001 |
Tuberculosis treatment: dangerous regimens?
Topics: Antitubercular Agents; Drug Administration Schedule; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Pyrazinamide; Rifampin; Streptomycin; Thioacetazone; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; World Health Organization | 2001 |
[Central nervous system tuberculosis in children: 2. Treatment and outcome].
Topics: Adolescent; Adrenal Cortex Hormones; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrocephalus; Hyponatremia; Infant; Isoniazid; Male; Prognosis; Pyrazinamide; Retrospective Studies; Rifampin; Treatment Outcome; Tuberculosis, Central Nervous System | 2001 |
Osteoarticular tuberculosis: current diagnosis and treatment.
Topics: Adult; Antitubercular Agents; Ethambutol; Humans; Isoniazid; Male; Mycobacterium; Osteoarthritis, Knee; Pyrazinamide; Rifampin; Streptomycin; Synovial Fluid; Tuberculosis, Osteoarticular | 2000 |
Higher activity of morphazinamide over pyrazinamide against intracellular.
Topics: Antitubercular Agents; Humans; Isoniazid; Macrophages; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrazinamide; Pyrazines; Sensitivity and Specificity | 2001 |
Increasing resistance of M. tuberculosis to anti-TB drugs in Saudi Arabia.
Topics: Antitubercular Agents; Drug Resistance, Microbial; Ethambutol; Female; Humans; Isoniazid; Male; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Prevalence; Pyrazinamide; Rifampin; Saudi Arabia; Streptomycin; Tuberculosis; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 2001 |
Ion interaction reagent reversed-phase high-performance liquid chromatography determination of anti-tuberculosis drugs and metabolites in biological fluids.
Topics: Aminosalicylic Acid; Animals; Antitubercular Agents; Calibration; Chromatography, High Pressure Liquid; Ethionamide; Humans; Isoniazid; Isonicotinic Acids; Niacin; Pyrazinamide; Pyrazines; Quality Control; Rats | 2001 |
Routine use of rapid molecular methods to detect antibiotic resistance in Mycobacterium tuberculosis.
Topics: Drug Resistance, Microbial; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Phenotype; Pyrazinamide; Rifampin | 2001 |
Multifocal extensive spinal tuberculosis (Pott's disease) involving cervical, thoracic and lumbar vertebrae.
Topics: Antitubercular Agents; Cervical Vertebrae; Ethambutol; Female; Humans; Isoniazid; Lumbar Vertebrae; Middle Aged; Pyrazinamide; Quadriplegia; Rifampin; Thoracic Vertebrae; Tomography, X-Ray Computed; Treatment Outcome; Tuberculosis, Spinal | 2001 |
New TB drug approved.
Topics: Antitubercular Agents; Drug Combinations; Humans; Isoniazid; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 1995 |
CPCRA researchers present OI studies at Vancouver.
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; Anti-Infective Agents; Antifungal Agents; Antitubercular Agents; Candidiasis; Child; Clarithromycin; Clinical Trials as Topic; DNA, Viral; Drug Therapy, Combination; Ethambutol; Female; Fluconazole; Humans; Isoniazid; Molluscum Contagiosum; Molluscum contagiosum virus; Multicenter Studies as Topic; Mycobacterium avium-intracellulare Infection; Ofloxacin; Patient Compliance; Pyrazinamide; Rifampin; Sequence Analysis, DNA; Tuberculosis | 1996 |
Medical advances with international impact.
Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antibiotics, Antitubercular; Antitubercular Agents; Clinical Trials as Topic; Developing Countries; Drug Therapy, Combination; Female; Health Services Accessibility; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Isoniazid; Pregnancy; Pregnancy Complications, Infectious; Pyrazinamide; Reagent Kits, Diagnostic; Rifampin; RNA, Viral; Tuberculosis; Viral Load; Zidovudine | 1998 |
New TB therapy works for HIV-positive patients.
Topics: Antitubercular Agents; Clinical Trials as Topic; Disease Progression; HIV Infections; Humans; Isoniazid; Patient Compliance; Pyrazinamide; Rifampin; Tuberculosis | 1998 |
Short course preventive therapy for tuberculosis is successful in HIV-infected patients.
Topics: AIDS-Related Opportunistic Infections; Clinical Trials as Topic; Drug Administration Schedule; Drug Therapy, Combination; Humans; Isoniazid; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis | 1998 |
[Efficacy of regimens containing INH, RFP with varied chemotherapy courses on retreated culture positive pneumoconio-tuberculosis].
Topics: Aged; Antitubercular Agents; Drug Therapy, Combination; Follow-Up Studies; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Silicotuberculosis; Streptomycin | 1998 |
Tuberculous otitis media -- a diagnostic dilemma.
Topics: Adult; Antitubercular Agents; Diagnosis, Differential; Drug Therapy, Combination; Ear Diseases; Facial Paralysis; Female; Hearing Loss; Hearing Loss, Conductive; Humans; Isoniazid; Mycobacterium Infections; Otitis Media; Pyrazinamide; Rifampin; Tinnitus; Tuberculosis | 2001 |
Modulating effect of Liv.100, an ayurvedic formulation on antituberculosis drug-induced alterations in rat liver microsomes.
Topics: Animals; Antitubercular Agents; Ascorbic Acid; Cytochrome b Group; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Cytochrome-B(5) Reductase; Drug Interactions; Glucose-6-Phosphatase; Herbal Medicine; India; Isoniazid; Lipid Peroxidation; Magnoliopsida; Male; Medicine, Ayurvedic; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Phytotherapy; Plant Extracts; Plants, Medicinal; Protective Agents; Pyrazinamide; Rats; Rats, Wistar; Rifampin | 2001 |
Rifampicin allergy confirmed by an intradermal test, but with a negative patch test.
Topics: Antitubercular Agents; Diagnosis, Differential; Drug Eruptions; Ethambutol; False Negative Reactions; Female; Humans; Intradermal Tests; Isoniazid; Middle Aged; Patch Tests; Peritonitis, Tuberculous; Pyrazinamide; Pyridoxine; Rifampin | 2001 |
Treatment of tuberculosis in Haiti.
Topics: Antitubercular Agents; Drug Administration Schedule; Drug Therapy, Combination; Ethambutol; Haiti; Health Services Research; Humans; Isoniazid; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis | 2001 |
[Effectiveness of chemotherapy of intrathoracic tuberculosis in children: late follow-up data].
Topics: Adolescent; Age Factors; Antibiotics, Antitubercular; Antitubercular Agents; Child; Child, Preschool; Follow-Up Studies; Humans; Isoniazid; Pyrazinamide; Rifampin; Time Factors; Tuberculosis, Lymph Node; Tuberculosis, Pulmonary | 2001 |
New mutations in pncA of in vitro selected pyrazinamide-resistant strains of Mycobacterium tuberculosis.
Topics: Amidohydrolases; Antitubercular Agents; DNA Primers; DNA, Bacterial; Drug Resistance, Microbial; Genome; Isoniazid; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Pyrazinamide; Reverse Transcriptase Polymerase Chain Reaction | 2001 |
Revised treatment and testing guidelines for latent tuberculosis infection.
Topics: Adolescent; Antitubercular Agents; Centers for Disease Control and Prevention, U.S.; Child; Child, Preschool; Humans; Isoniazid; Practice Guidelines as Topic; Pyrazinamide; Rifampin; Risk Factors; Societies, Medical; Tuberculosis; United States | 2000 |
Isonicotinic acid hydrazide induced anagen effluvium and associated lichenoid eruption.
Topics: Adult; Alopecia; Antitubercular Agents; Ethambutol; Female; Humans; Isoniazid; Lichenoid Eruptions; Pyrazinamide; Rifampin; Scalp Dermatoses; Tuberculosis, Gastrointestinal | 2001 |
Liquid chromatographic determination of isoniazid, pyrazinamide and rifampicin from pharmaceutical preparations and blood.
Topics: Antitubercular Agents; Chromatography, High Pressure Liquid; Humans; Isoniazid; Pharmaceutical Preparations; Pyrazinamide; Rifampin; Sensitivity and Specificity; Spectrophotometry, Ultraviolet | 2002 |
Tuberculosis presenting as immune thrombocytopenic purpura.
Topics: Anti-Bacterial Agents; Antitubercular Agents; Autoimmune Diseases; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Lymph Nodes; Middle Aged; Mycobacterium tuberculosis; Purpura, Thrombocytopenic, Idiopathic; Pyrazinamide; Pyridoxine; Rifampin; Tuberculosis | 2002 |
Can serial qualitative polymerase chain reaction monitoring predict outcome of pulmonary tuberculosis treatment?
Topics: Antitubercular Agents; Ethambutol; Female; Follow-Up Studies; Humans; Isoniazid; Male; Pyrazinamide; Rifampin; Sputum; Time Factors; Tuberculosis, Pulmonary | 2001 |
Assessment of bioequivalence of rifampicin, isoniazid and pyrazinamide in a four drug fixed dose combination with separate formulations at the same dose levels.
Topics: Analysis of Variance; Antitubercular Agents; Biological Availability; Chemistry, Pharmaceutical; Cross-Over Studies; Drug Combinations; Humans; Isoniazid; Male; Pyrazinamide; Rifampin; Therapeutic Equivalency | 2002 |
Tuberculous meningoencephalitis in HIV-seronegative patients: variety of clinical presentation and impact on diagnostics and treatment.
Topics: Adult; Aged; Antitubercular Agents; Brain; Drug Therapy, Combination; Ethambutol; Female; HIV Seronegativity; Humans; Isoniazid; Lumbar Vertebrae; Magnetic Resonance Imaging; Male; Middle Aged; Pyrazinamide; Rifampin; Tuberculosis, Meningeal | 2001 |
[Latent tuberculosis infection: diagnosis and treatment].
Topics: Antitubercular Agents; BCG Vaccine; Humans; Isoniazid; Predictive Value of Tests; Pyrazinamide; Rifampin; Tuberculin Test; Tuberculosis | 2002 |
Tuberculosis preventative treatment also prevented diarrhoea in HIV-infected patients in Zambia.
Topics: Antibiotics, Antitubercular; Antitubercular Agents; Diarrhea; Drug Therapy, Combination; Follow-Up Studies; HIV Infections; Humans; Incidence; Isoniazid; Pyrazinamide; Retrospective Studies; Rifampin; Treatment Outcome; Tuberculosis; Zambia | 2002 |
Noncompliance with tuberculosis treatment by patients at a tuberculosis and AIDS reference hospital in midwestern Brazil.
Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Aged; Antitubercular Agents; Brazil; Child; Child, Preschool; Female; Hospitals; Humans; Infant; Infant, Newborn; Isoniazid; Male; Medical Records; Middle Aged; Patients; Pyrazinamide; Rifampin; Risk Factors; Treatment Refusal; Tuberculosis | 2002 |
Tuberculous pericarditis in an infant evolving during triple chemotherapy.
Topics: Antitubercular Agents; Child, Preschool; Drug Therapy, Combination; Echocardiography; Female; Humans; Isoniazid; Pericardial Effusion; Pericarditis, Tuberculous; Pyrazinamide; Rifampin; Tomography, X-Ray Computed; Treatment Outcome; Tuberculosis, Pulmonary | 2002 |
Erythema nodosum associated with reactivation tuberculous lymphadenitis (scrofula).
Topics: Aged; Antitubercular Agents; Diagnosis, Differential; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Leg; Mycobacterium tuberculosis; Neck; Pyrazinamide; Rifampin; Tomography, X-Ray Computed; Tuberculosis, Lymph Node | 2002 |
Diagnostic criteria for Tuberculous Meningitis.
Topics: Antitubercular Agents; Child; Child, Preschool; Humans; Isoniazid; Mycobacterium tuberculosis; Prognosis; Pyrazinamide; Rifampin; Sensitivity and Specificity; Streptomycin; Tuberculin Test; Tuberculosis, Meningeal | 2002 |
Complete resolution of cervical spinal tuberculosis with paraplegia in pregnancy.
Topics: Adult; Antitubercular Agents; Cervical Vertebrae; Diagnosis, Differential; Female; Humans; Infant, Newborn; Isoniazid; Magnetic Resonance Imaging; Paraplegia; Pregnancy; Pregnancy Complications, Infectious; Pyrazinamide; Pyridoxine; Rifampin; Tuberculosis, Spinal | 2002 |
Role of poly [DL-lactide-co-glycolide] in development of a sustained oral delivery system for antitubercular drug(s).
Topics: Administration, Oral; Animals; Antibiotics, Antitubercular; Antitubercular Agents; Area Under Curve; Biocompatible Materials; Capsules; Delayed-Action Preparations; Drug Compounding; Female; Half-Life; Isoniazid; Lactic Acid; Male; Mice; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Pyrazinamide; Rifampin; Solubility | 2002 |
Use of molecular techniques to distinguish between treatment failure and exogenous reinfection with Mycobacterium tuberculosis.
Topics: Adult; Aged; Antibiotics, Antitubercular; Antitubercular Agents; Bacterial Typing Techniques; DNA Fingerprinting; Drug Administration Schedule; Drug Resistance, Bacterial; Ethambutol; Female; Genetics, Microbial; Humans; Isoniazid; Kanamycin; Male; Middle Aged; Mycobacterium tuberculosis; Polymorphism, Restriction Fragment Length; Pyrazinamide; Recurrence; Retrospective Studies; Rifampin; Streptomycin; Treatment Failure; Tuberculosis, Pulmonary | 2002 |
Validation of a RP-LC method for the simultaneous determination of isoniazid, pyrazinamide and rifampicin in a pharmaceutical formulation.
Topics: Antitubercular Agents; Chromatography, High Pressure Liquid; Drug Combinations; Isoniazid; Pharmaceutical Preparations; Pyrazinamide; Reproducibility of Results; Rifampin; Sensitivity and Specificity | 2002 |
Simple fibroblast-based assay for screening of new antimicrobial drugs against Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Cell Survival; Cells, Cultured; Colony Count, Microbial; Drug Evaluation, Preclinical; Fibroblasts; Humans; Isoniazid; L-Lactate Dehydrogenase; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrazinamide | 2002 |
Perianal ulceration in a "healthy" Chinese man with disseminated tuberculosis.
Topics: Aged; Antitubercular Agents; Anus Diseases; Humans; Isoniazid; Male; Mycobacterium tuberculosis; Polymerase Chain Reaction; Pyrazinamide; Rifampin; Tuberculosis, Cutaneous | 2002 |
Antitubercular therapy decreases nitric oxide production in HIV/TB coinfected patients.
Topics: Adult; Antibiotics, Antitubercular; Antitubercular Agents; Biomarkers; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Citrulline; Drug Administration Schedule; Enzyme Inhibitors; Ethambutol; Female; HIV Infections; Humans; Isoniazid; Male; Middle Aged; Mycobacterium; Nitric Oxide; Nitrites; Pyrazinamide; Rifampin; T-Lymphocyte Subsets; Tuberculosis | 2002 |
[A case of tuberculosis pleuritis developing contralateral pleural effusion during anti-tuberculosis chemotherapy, falling into chronic respiratory failure].
Topics: Aged; Antitubercular Agents; Chronic Disease; Drug Therapy, Combination; Humans; Isoniazid; Male; Pleural Effusion; Pyrazinamide; Respiratory Insufficiency; Rifampin; Tuberculosis, Pleural | 2002 |
Risk factors for antituberculous chemotherapy-induced hepatotoxicity in Japanese pediatric patients.
Topics: Adolescent; Analysis of Variance; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Isoniazid; Japan; Liver; Male; Medical Records; Pyrazinamide; Retrospective Studies; Rifampin; Risk Factors | 2002 |
Pulmonary alveolar proteinosis and tuberculosis in a diabetic patient: a rare or a seldom diagnosed association?
Topics: Adult; Diabetes Complications; Female; Humans; Isoniazid; Mycobacterium tuberculosis; Pulmonary Alveolar Proteinosis; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 2002 |
Long-term follow up of childhood tuberculous meningitis.
Topics: Acetazolamide; Anti-Inflammatory Agents; Antitubercular Agents; Brain; Child; Cognition Disorders; Diuretics; Drug Therapy, Combination; Ethionamide; Female; Follow-Up Studies; Furosemide; Humans; Hydrocephalus; Isoniazid; Male; Mycobacterium tuberculosis; Prednisolone; Pyrazinamide; Quality of Life; Rifampin; Tuberculosis, Meningeal; Ventriculoperitoneal Shunt; Wechsler Scales | 2002 |
[Chemotherapy with isoniazid and rifampicin for pulmonary tuberculosis].
Topics: Antitubercular Agents; Drug Therapy, Combination; Humans; Isoniazid; Japan; Pyrazinamide; Reference Standards; Rifampin; Surveys and Questionnaires; Tuberculosis, Pulmonary | 2002 |
Behavior of uptake of moisture by drugs and excipients under accelerated conditions of temperature and humidity in the absence and the presence of light. 1. Pure anti-tuberculosis drugs and their combinations.
Topics: Adsorption; Antitubercular Agents; Darkness; Drug Combinations; Drug Stability; Ethambutol; Excipients; Isoniazid; Light; Pyrazinamide; Rifampin; Temperature; Water | 2002 |
Frequency of recurrence among MDR-tB cases 'successfully' treated with standardised short-course chemotherapy.
Topics: Adult; Antibiotics, Antitubercular; Antitubercular Agents; Drug Administration Schedule; Drug Combinations; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Recurrence; Rifampin; Russia; Streptomycin; Time Factors; Treatment Failure; Tuberculosis, Multidrug-Resistant | 2002 |
Determination of antitubercular drugs by micellar electrokinetic capillary chromatography (MEKC).
Topics: Antitubercular Agents; Chromatography, Micellar Electrokinetic Capillary; Isoniazid; Pyrazinamide; Rifampin | 2002 |
Summaries for patients. Short-course treatment for latent tuberculosis is associated with more frequent liver injury than long-course treatment is.
Topics: Adult; Antibiotics, Antitubercular; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Isoniazid; Liver; Liver Function Tests; Male; Pyrazinamide; Rifampin | 2002 |
Tuberculosis re-treatment outcomes within the public service in Nairobi, Kenya.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; AIDS-Related Opportunistic Infections; Antitubercular Agents; Drug Therapy, Combination; Female; HIV Seropositivity; Humans; Isoniazid; Kenya; Male; Middle Aged; Pyrazinamide; Recurrence; Retrospective Studies; Rifampin; Treatment Outcome; Tuberculosis, Pulmonary | 2002 |
[Pulmonary tuberculosis presenting as tubercular lupus].
Topics: Adolescent; Antitubercular Agents; Biopsy; Drug Combinations; Female; Humans; Isoniazid; Lupus Vulgaris; Luxembourg; Philippines; Pyrazinamide; Rifampin; Sputum; Tomography, X-Ray Computed; Tuberculosis, Pulmonary | 2002 |
The triad of weight loss, fever and night sweating: isolated bone marrow tuberculosis, a case report.
Topics: Antitubercular Agents; Bone Marrow; Diagnosis, Differential; Fever; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Streptomycin; Sweating; Tuberculosis, Miliary; Weight Loss | 2002 |
[Effect of levofloxacine on cell elements of the lung tissue and on the growth of drug resistant Mycobacteria tuberculosis].
Topics: Animals; Anti-Infective Agents; Antitubercular Agents; Cell Movement; Culture Techniques; Drug Interactions; Drug Resistance, Multiple, Bacterial; Isoniazid; Levofloxacin; Lung; Lymphocytes; Macrophages; Mice; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Rifampin | 2002 |
[Myrin P in the combined treatment of tuberculosis].
Topics: Adolescent; Adult; Antitubercular Agents; Drug Combinations; Drug Resistance, Multiple, Bacterial; Ethambutol; Humans; Isoniazid; Middle Aged; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 2002 |
Population pharmacokinetics of antituberculous drugs and treatment of Mycobacterium bovis infection in bongo antelope (Tragelaphus eurycerus isaaci).
Topics: Amikacin; Animals; Antelopes; Antitubercular Agents; Area Under Curve; Ethambutol; Female; Isoniazid; Levofloxacin; Male; Mycobacterium bovis; Ofloxacin; Pyrazinamide; Rifampin; Tuberculosis | 2002 |
Treatment of isoniazid-resistant tuberculosis with isoniazid, rifampin, ethambutol, and pyrazinamide for 6 months.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Antibiotics, Antitubercular; Child; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Microbial Sensitivity Tests; Middle Aged; Mycobacterium tuberculosis; Pyrazinamide; Retrospective Studies; Rifampin; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 2002 |
[The evolution of threshold values of air conduction in the extended high frequency range (9-18 kHz) in patients suffering from the pulmonary tuberculosis treated with combination of SM, INH, RFM, and PZA].
Topics: Adult; Antitubercular Agents; Audiometry, Pure-Tone; Auditory Threshold; Case-Control Studies; Deafness; Dose-Response Relationship, Drug; Humans; Isoniazid; Male; Middle Aged; Poland; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Pulmonary | 2002 |
Bactericidal and sterilizing activities of antituberculosis drugs during the first 14 days.
Topics: Antibiotics, Antitubercular; Antitubercular Agents; Colony Count, Microbial; Confidence Intervals; Drug Resistance, Bacterial; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Probability; Pyrazinamide; Rifampin; Sensitivity and Specificity; Sputum; Streptomycin; Time Factors; Tuberculosis, Pulmonary | 2003 |
Pyrazinamide and rifampin vs isoniazid for the treatment of latent tuberculosis: improved completion rates but more hepatotoxicity.
Topics: Adolescent; Adult; Aged; Antibiotics, Antitubercular; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Female; Humans; Isoniazid; Male; Middle Aged; Patient Compliance; Prospective Studies; Pyrazinamide; Rifampin; Severity of Illness Index; Tuberculosis, Pulmonary | 2003 |
Prognosis of tuberculous meningitis in adults in the era of modern antituberculous chemotherapy.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Drug Therapy, Combination; Ethambutol; Female; Humans; Immunocompromised Host; Isoniazid; Leukocyte Count; Male; Mycobacterium tuberculosis; Prognosis; Pyrazinamide; Rifampin; Streptomycin; Treatment Outcome; Tuberculosis, Meningeal | 2002 |
Incidence of serious side effects from first-line antituberculosis drugs among patients treated for active tuberculosis.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Drug Eruptions; Ethambutol; Female; HIV Seropositivity; Humans; Incidence; Isoniazid; Male; Middle Aged; Proportional Hazards Models; Pyrazinamide; Rifampin; Risk Factors; Tuberculosis, Pulmonary | 2003 |
Drug-resistant Mycobacterium tuberculosis among new tuberculosis patients, Yangon, Myanmar.
Topics: AIDS-Related Opportunistic Infections; Drug Resistance, Bacterial; Ethambutol; Humans; Isoniazid; Myanmar; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Streptomycin; Treatment Failure; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 2003 |
Evaluation of the recently reported USP gradient HPLC method for analysis of anti-tuberculosis drugs for its ability to resolve degradation products of rifampicin.
Topics: Antibiotics, Antitubercular; Antitubercular Agents; Chromatography, High Pressure Liquid; Drug Combinations; Ethambutol; Isoniazid; Pharmacopoeias as Topic; Pyrazinamide; Reference Standards; Rifampin; Tablets; United States | 2003 |
The decline of high drug resistance rate of pulmonary Mycobacterium tuberculosis isolates from a southern Taiwan medical centre, 1996-2000.
Topics: Antitubercular Agents; Cycloserine; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Ethambutol; Humans; In Vitro Techniques; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrazinamide; Retrospective Studies; Rifampin; Streptomycin; Taiwan; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 2003 |
Low level of compliance with tuberculosis treatment in children: monitoring by urine tests.
Topics: Antibiotics, Antitubercular; Antitubercular Agents; Child; Drug Therapy, Combination; Humans; Isoniazid; Patient Compliance; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 2003 |
Choroidal tuberculoma in miliary tuberculosis.
Topics: Adult; Anti-Bacterial Agents; Antitubercular Agents; Choroid Diseases; Drug Therapy, Combination; Enzyme-Linked Immunosorbent Assay; Ethambutol; Fluorescein Angiography; Humans; Isoniazid; Male; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Sputum; Tomography, X-Ray Computed; Tuberculoma; Tuberculosis, Miliary; Tuberculosis, Ocular; Ultrasonography | 2003 |
Alginate-based oral drug delivery system for tuberculosis: pharmacokinetics and therapeutic effects.
Topics: Administration, Oral; Alginates; Animals; Antibiotics, Antitubercular; Antitubercular Agents; Area Under Curve; Drug Compounding; Excipients; Guinea Pigs; Half-Life; Hydrogels; Isoniazid; Pneumococcal Infections; Pyrazinamide; Rifampin; Solubility | 2003 |
Anti-tuberculosis 4FDC tablets--mystery to chemistry.
Topics: Antibiotics, Antitubercular; Antitubercular Agents; Drug Combinations; Drug Stability; Drug Storage; Ethambutol; Humans; Isoniazid; Pyrazinamide; Rifampin; Tablets; Tuberculosis | 2003 |
Pharmaceutical formulation of a fixed-dose anti-tuberculosis combination.
Topics: Administration, Oral; Antibiotics, Antitubercular; Antitubercular Agents; Chemistry, Pharmaceutical; Dose-Response Relationship, Drug; Drug Combinations; Drug Compounding; Ethambutol; Excipients; Feasibility Studies; Humans; Isoniazid; Powders; Pyrazinamide; Rifampin; Tuberculosis | 2003 |
A pilot stability study on four-drug fixed-dose combination anti-tuberculosis products.
Topics: Antibiotics, Antitubercular; Antitubercular Agents; Biological Availability; Drug Combinations; Drug Labeling; Drug Packaging; Drug Stability; Drug Storage; Ethambutol; Humans; Isoniazid; Pilot Projects; Pyrazinamide; Rifampin; Tablets; Time Factors; Tuberculosis | 2003 |
Treatment outcome of tuberculosis among Saudi nationals: role of drug resistance and compliance.
Topics: Antibiotics, Antitubercular; Female; Humans; Isoniazid; Male; Mycobacterium tuberculosis; Prevalence; Pyrazinamide; Retrospective Studies; Rifampin; Saudi Arabia; Treatment Failure; Treatment Outcome; Treatment Refusal; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 2003 |
[Tuberculous peripheral multifocal choroiditis].
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Antitubercular Agents; Choroiditis; Drug Therapy, Combination; Female; Humans; Isoniazid; Macular Edema; Middle Aged; Pyrazinamide; Radiography; Rifampin; Tuberculin Test; Tuberculosis, Ocular; Tuberculosis, Pulmonary | 2003 |
[Tuberculous otitis media. Report of 3 cases].
Topics: Adult; Aged; Amoxicillin; Antitubercular Agents; Cerebrospinal Fluid Otorrhea; Drug Combinations; Ear Diseases; Female; Humans; Isoniazid; Male; Mycobacterium Infections; Mycobacterium tuberculosis; Otitis Media; Penicillins; Proteus Infections; Proteus mirabilis; Pyrazinamide; Rifampin; Staphylococcal Infections; Staphylococcus aureus; Tuberculosis | 2003 |
[Evaluation of levofloxacin antitubercular activity in vitro and in lung tissue culture].
Topics: Anti-Infective Agents; Antitubercular Agents; Drug Therapy, Combination; Isoniazid; Levofloxacin; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide | 2002 |
Follow-up of compliance with tuberculosis treatment in children: monitoring by urine tests.
Topics: Antitubercular Agents; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Isoniazid; Male; Monitoring, Physiologic; Patient Compliance; Prospective Studies; Pyrazinamide; Rifampin; Sensitivity and Specificity; Treatment Outcome; Tuberculosis, Pulmonary; Turkey; Urinalysis; Urine | 2003 |
[The short-term and long-term treatment outcomes in patients with pulmonary tuberculosis positive for drug-resistant and sensitive strains].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antitubercular Agents; Child; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Recurrence; Rifampin; Streptomycin; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 2003 |
[Follow-up observation on relapse of smear negative pulmonary tuberculosis after short-course chemotherapy].
Topics: Antitubercular Agents; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Isoniazid; Male; Mycobacterium tuberculosis; Pyrazinamide; Recurrence; Rifampin; Sputum; Streptomycin; Treatment Outcome; Tuberculosis, Pulmonary | 2003 |
Bilateral bone loss of the maxilla.
Topics: Adult; Alveolar Bone Loss; Diagnosis, Differential; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Maxillary Diseases; Pyrazinamide; Rifampin; Tuberculosis, Oral | 2003 |
Chemotherapeutic potential of orally administered poly(lactide-co-glycolide) microparticles containing isoniazid, rifampin, and pyrazinamide against experimental tuberculosis.
Topics: Animals; Antibiotics, Antitubercular; Antitubercular Agents; Area Under Curve; Biocompatible Materials; Biological Availability; Capsules; Drug Combinations; Drug Compounding; Isoniazid; Lactic Acid; Mice; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Pyrazinamide; Rifampin; Tissue Distribution; Tuberculosis, Pulmonary | 2003 |
Antituberculous therapy-induced toxicity.
Topics: Adult; Antitubercular Agents; Drug Therapy, Combination; Fever; Humans; Isoniazid; Male; Pyrazinamide; Respiratory Distress Syndrome; Seizures; Tuberculosis, Urogenital | 2003 |
Pyrazinamide-isoniazid in tuberculosis.
Topics: Isomerism; Isoniazid; Niacin; Nicotinic Acids; Pyrazinamide; Tuberculosis | 1954 |
Observations on the combined use of pyrazinamide (Aldinamide) and isoniazid in the treatment of pulmonary tuberculosis; a clinical study.
Topics: Isoniazid; Niacin; Nicotinic Acids; Pyrazinamide; Tuberculosis; Tuberculosis, Pulmonary | 1954 |
The chemotherapy of pulmonary tuberculosis with pyrazinamide used alone and in combination with streptomycin, para-aminosalicylic acid, or isoniazid.
Topics: Aminosalicylic Acid; Isomerism; Isoniazid; Niacin; Nicotinic Acids; Pyrazinamide; Streptomycin; Tuberculosis; Tuberculosis, Pulmonary | 1954 |
Pyrazinamide-isoniazid in tuberculosis. I. Results in 58 patients with pulmonary lesions one year after the start of therapy.
Topics: Isomerism; Isoniazid; Niacin; Nicotinic Acids; Pyrazinamide; Tuberculosis; Tuberculosis, Pulmonary | 1954 |
The influence of pyrazinamide-isoniazid on M. tuberculosis in animals and man.
Topics: Isomerism; Isoniazid; Leadership; Mycobacterium tuberculosis; Niacin; Nicotinic Acids; Pyrazinamide; Tuberculosis | 1954 |
The pyrazinamide susceptibility of isoniazid-resistant mutants of tubercle bacilli.
Topics: Bacillus; Disease Susceptibility; Gram-Positive Bacteria; Isoniazid; Lacticaseibacillus casei; Mycobacterium tuberculosis; Niacin; Nicotinic Acids; Pyrazinamide | 1955 |
Pyrazinamide-isoniazid in tuberculosis. III. Observations with reduced dosage of pyrazinamide.
Topics: Clinical Protocols; Isoniazid; Niacin; Nicotinic Acids; Pyrazinamide; Tuberculosis; Tuberculosis, Pulmonary | 1955 |
Pyrazinamide-isoniazid: comparison with isoniazid-para-aminosalicylic acid in active pulmonary tuberculosis with the choice of regimens determined by chance.
Topics: Aminosalicylic Acid; Isoniazid; Niacin; Nicotinic Acids; Pyrazinamide; Pyrimidines; Tuberculosis; Tuberculosis, Pulmonary | 1956 |
[First results in the treatment of tuberculous meningitis with the use of pyrazinamide and the first studies on its action on isoniazid-resistant strains].
Topics: Isomerism; Isoniazid; Niacin; Nicotinic Acids; Pyrazinamide; Pyrimidines; Tuberculosis; Tuberculosis, Meningeal | 1956 |
Polarographic determination of pyrazinamide serum and plasma concentration in the presence of isoniazid.
Topics: Blood; Humans; Isomerism; Isoniazid; Niacin; Nicotinic Acids; Polarography; Pyrazinamide; Pyrimidines | 1956 |
The occurrence of hyperuricemia during pyrazinamide-isoniazid therapy.
Topics: Blood; Humans; Hyperuricemia; Isomerism; Isoniazid; Niacin; Nicotinic Acids; Pyrazinamide; Pyrimidines; Uric Acid | 1956 |
[Clinical experiences with pyrazinamide].
Topics: Aminosalicylic Acid; Isoniazid; Niacin; Nicotinic Acids; Pyrazinamide; Streptomycin; Tuberculosis; Tuberculosis, Pulmonary | 1956 |
[Further observations on pyrazinamide].
Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Dermatologic Agents; Isoniazid; Pyrazinamide; Tuberculosis; Tuberculosis, Pulmonary | 1956 |
Pyrazinamide together with oxytetracycline in patients with tubercle bacilli resistant to streptomycin, PAS and isoniazid.
Topics: Aminosalicylic Acid; Bacillus; Isoniazid; Lacticaseibacillus casei; Niacin; Nicotinic Acids; Oxytetracycline; Pyrazinamide; Streptomycin; Tuberculosis; Tuberculosis, Pulmonary | 1957 |
[Combination of pyrazinamide & isoniazid in experimental tuberculosis in guinea pigs].
Topics: Animals; Guinea Pigs; Isoniazid; Niacin; Nicotinic Acids; Pyrazinamide; Tuberculosis | 1956 |
Pyrazinamide-isoniazid in patients with previous isoniazid therapy.
Topics: Isoniazid; Niacin; Nicotinic Acids; Pyrazinamide; Tuberculosis; Tuberculosis, Pulmonary | 1957 |
[Treatment of pulmonary tuberculosis with high alternating dosage of pyrazinamide and isoniazid].
Topics: Isoniazid; Niacin; Nicotinic Acids; Pyrazinamide; Tuberculosis; Tuberculosis, Pulmonary | 1957 |
[Pyrazinamide-isoniazid mixture in the treatment of chronic pulmonary tuberculosis].
Topics: Humans; Isoniazid; Niacin; Nicotinic Acids; Pyrazinamide; Tuberculosis; Tuberculosis, Pulmonary | 1957 |
Comparative efficacy of the concurrent use of pyrazinamide and isoniazid with that of other forms of therapy in the treatment of pulmonary tuberculosis.
Topics: Isoniazid; Pyrazinamide; Tuberculosis; Tuberculosis, Pulmonary | 1957 |
[Pyrazinamide & pyrazinamide with isoniazid in pulmonary tuberculosis; comparison with other chemotherapeuticantibiotic combinations].
Topics: Humans; Isoniazid; Niacin; Nicotinic Acids; Pyrazinamide; Tuberculosis; Tuberculosis, Pulmonary | 1957 |
[Combined pyrazinamide and isoniazid in therapy of pulmonary tuberculosis].
Topics: Isoniazid; Niacin; Nicotinic Acids; Pyrazinamide; Tuberculosis; Tuberculosis, Pulmonary | 1957 |
[Radiological records of the results of combined pyrazinamide-streptomycin-isoniazid therapy].
Topics: Isoniazid; Niacin; Nicotinic Acids; Pyrazinamide; Radiology; Streptomycin; Tuberculosis; Tuberculosis, Pulmonary | 1958 |
[Studies on the changes of the daily amount of tubercle bacilli present in sputum and its resistance against drugs, when patients have been treated with anti-tuberculous agents. I. Combined therapy with pyrazinamide and isonicotinic acid hydrazide].
Topics: Bacillus; Humans; Isoniazid; Lung; Pyrazinamide; Sputum; Tuberculosis; Tuberculosis, Pulmonary | 1958 |
[Experimental studies on the mode of action of pyrazinamide. I. The relation with isoniazid].
Topics: Isoniazid; Niacin; Nicotinic Acids; Pyrazinamide; Tuberculosis | 1958 |
[Pyrazinamide-isoniazid combination in treatment of bone tuberculosis].
Topics: Humans; Isoniazid; Niacin; Nicotinic Acids; Pyrazinamide; Tuberculosis; Tuberculosis, Osteoarticular | 1958 |
Pyrazinamide in low dosage in combination with isoniazid or paraaminosalicylic acid in the treatment of pulmonary tuberculosis.
Topics: Aminosalicylic Acid; Isoniazid; Niacin; Nicotinic Acids; Pyrazinamide; Tuberculosis; Tuberculosis, Pulmonary | 1959 |
The use of pyrazinamide plus isoniazid in the treatment of pulmonary tuberculosis.
Topics: Isomerism; Isoniazid; Niacin; Nicotinic Acids; Pyrazinamide; Tuberculosis; Tuberculosis, Pulmonary | 1959 |
[Tests of liver function during pyrazinamide therapy].
Topics: Child; Humans; Infant; Isoniazid; Liver; Niacin; Nicotinic Acids; Pyrazinamide; Tuberculosis; Tuberculosis, Meningeal; Tuberculosis, Pulmonary | 1959 |
Retreatment of pulmonary tuberculosis. Experiences with various combinations of pyrazinamide, cycloserine, and kanamycin in patients excreting tubercle bacilli resistant to both streptomycin and isoniazid.
Topics: Anti-Bacterial Agents; Bacillus; Cycloserine; Humans; Isoniazid; Kanamycin; Pyrazinamide; Retreatment; Streptomycin; Tuberculosis; Tuberculosis, Pulmonary | 1960 |
Retreatment of tuberculous patients: an experience with the combined use of high doses of isoniazid, pyrazinamide and cycloserine.
Topics: Cycloserine; Isoniazid; Pyrazinamide; Retreatment; Tuberculosis; Tuberculosis, Pulmonary | 1961 |
Influences of sodium para-amino salicylate, pyrazinamide, and isonicotinic acid hydrazide upon the growth of timothy.
Topics: Aminosalicylic Acid; Biological Phenomena; Isoniazid; Phleum; Physiological Phenomena; Plant Physiological Phenomena; Pyrazinamide; Sodium; Sodium Salicylate | 1961 |
Pyrazinamide-isoniazid treated tuberculous patients: a five year follow-up.
Topics: Follow-Up Studies; Humans; Isoniazid; Pyrazinamide; Tuberculosis; Tuberculosis, Pulmonary | 1959 |
Treatment of pulmonary tuberculosis with isoniazid and pyrazinamide: experience in 114 cases.
Topics: Humans; Isoniazid; Pyrazinamide; Tuberculosis, Pulmonary | 1959 |
Unusual reactions to anti-tuberculous chemotherapy.
Topics: Hepatitis; Hepatitis A; Humans; Isoniazid; Pyrazinamide; Tuberculosis; Uric Acid | 1960 |
SEQUENTIAL use of paired combinations of isoniazid, streptomycin, para-aminosalicylic acid, and pyrazinamide. A United States Public Health Service tuberculosis therapy trial.
Topics: Aminosalicylic Acid; Antitubercular Agents; Isoniazid; Pyrazinamide; Streptomycin; Tuberculosis; United States; United States Public Health Service | 1959 |
Successful treatment of advanced isonizid- and streptomycin-resistant pulmonary tuberculosis with ethionamide, pyrazinamide, and isoniazid.
Topics: Drug Resistance; Drug Resistance, Microbial; Ethionamide; Humans; Isoniazid; Pyrazinamide; Streptomycin; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 1962 |
The tate of patients with drug-resistant tubercle bacilli and pulmonary tuberculosis.
Topics: Anti-Bacterial Agents; Bacillus; Cycloserine; Drug Resistance; Drug Resistance, Microbial; Ethionamide; Isoniazid; Pyrazinamide; Streptomycin; Tetracycline; Tuberculosis; Tuberculosis, Pulmonary; Viomycin | 1962 |
[On the treatment of adult-type pulmonary tuberculosis during puberty with isoniazid plus pyrazinamide].
Topics: Adult; Humans; Isoniazid; Puberty; Pyrazinamide; Sexual Maturation; Tuberculosis, Pulmonary | 1962 |
[The importance of medical treatment of pulmonary tuberculosis from a new viewpoint].
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Cycloserine; Dihydrostreptomycin Sulfate; Ethionamide; Iproniazid; Isoniazid; Kanamycin; Oxytetracycline; Pyrazinamide; Streptomycin; Thiosemicarbazones; Tuberculosis; Tuberculosis, Pulmonary; Viomycin | 1962 |
[Pyrazinamide in association with streptomycin, PAS and isoniazid in the therapy of pulmonary tuberculosis].
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Humans; Isoniazid; Pyrazinamide; Streptomycin; Tuberculosis; Tuberculosis, Pulmonary | 1962 |
Preliminary experiments on the use of "the air-tight cultivation method" in determining blood levels of drugs during the chemotherapy of tuberculosis.
Topics: Bacteriological Techniques; Blood Chemical Analysis; Humans; Isoniazid; Mycobacterium tuberculosis; Pyrazinamide; Streptomycin; Tuberculosis | 1963 |
The eradication of Mycobacterium tuberculosis from the sputum of patients treated with pyrazinamide and isoniazid. A ten-year follow-up study.
Topics: Follow-Up Studies; Humans; Isoniazid; Mycobacterium tuberculosis; Pyrazinamide; Pyridazines; Sputum | 1962 |
[Various biological tests on several groups of subjects with tuberculosis subjected respectively to monotherapy with isoniazid, viomycin, pyrazinamide, cycloserine, ethioniamide and kanamycin].
Topics: Cycloserine; Ethionamide; Isoniazid; Kanamycin; Pyrazinamide; Tuberculosis; Tuberculosis, Pulmonary; Viomycin | 1962 |
DRUG THERAPY FOR TUBERCULOUS PATIENTS OUTSIDE THE HOSPITAL.
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Cycloserine; Drug Hypersensitivity; Drug Resistance; Drug Resistance, Microbial; Ethionamide; Isoniazid; Pyrazinamide; Streptomycin; Tuberculosis; Viomycin | 1963 |
[EFFECTS OF ETHIONAMIDE ON TUBERCLE BACILLI RESISTANT TO VARIOUS ANTITUBERCULAR AGENTS AND THE EFFECTS OF THESE AGENTS ON ETHIONAMIDE-RESISTANT TUBERCLE BACILLI].
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Antitubercular Agents; Bacillus; Cycloserine; Drug Resistance; Drug Resistance, Microbial; Ethionamide; Isoniazid; Kanamycin; Mycobacterium tuberculosis; Pyrazinamide; Research; Streptomycin; Thiosemicarbazones | 1963 |
[SYMPOSIUM: COUNTER-MEASURES IN INTRACTABLE PULMONARY TUBERCULOSIS].
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Antitubercular Agents; Cycloserine; Ethionamide; Isoniazid; Kanamycin; Pneumonectomy; Pyrazinamide; Streptomycin; Thiosemicarbazones; Tuberculosis, Pulmonary | 1963 |
[THE FOCUS OF INOCULATION IN GUINEA PIGS DURING TREATMENT WITH MORFOZINAMIDE. (INFECTION WITH STRAINS SENSITIVE AND RESISTANT TO CHEMOTHERAPY AND ANTIBIOTICS].
Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antitubercular; Antitubercular Agents; Drug Resistance; Drug Resistance, Microbial; Guinea Pigs; Isoniazid; Pyrazinamide; Research; Streptomycin; Tuberculosis | 1963 |
MODERN DRUG TREATMENT OF MYCOBACTERIAL DISEASES.
Topics: Adrenal Cortex Hormones; Aminosalicylic Acid; Aminosalicylic Acids; Antitubercular Agents; Cycloserine; Ethionamide; Humans; Isoniazid; Kanamycin; Oxytetracycline; Pyrazinamide; Streptomycin; Thioacetazone; Thiosemicarbazones; Toxicology; Tuberculosis; Tuberculosis, Pulmonary; Viomycin | 1963 |
SIDE EFFECTS OF AN ANTITUBERCULOUS FIVE-DRUG REGIMEN: ETHIONAMIDE, CYCLOSERINE, PYRAZINAMIDE, VIOMYCIN AND ISONIAZID.
Topics: Amyloidosis; Antitubercular Agents; Cycloserine; Deafness; Drug Hypersensitivity; Duodenal Ulcer; Ethionamide; Isoniazid; Kidney Diseases; Liver Diseases; Neuritis; Psychotic Disorders; Pyrazinamide; Toxicology; Tuberculosis; Tuberculosis, Pulmonary; Vertigo; Viomycin | 1963 |
[EXPERIENCE WITH A NONSPECIFIC ANTIINFLAMMATORY AGENT IN PULMONARY TUBERCULOSIS].
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Anti-Inflammatory Agents; Cycloserine; Drug Resistance; Drug Resistance, Microbial; Isoniazid; Oxyphenbutazone; Prognosis; Pyrazinamide; Tuberculosis; Tuberculosis, Pulmonary | 1963 |
DRUG RESISTANT MYCOBACTERIAL INFECTION AND ITS RESPONSE TO TREATMENT.
Topics: Cycloserine; Drug Resistance; Drug Resistance, Microbial; Humans; Isoniazid; Mycobacterium; Mycobacterium Infections; Mycobacterium tuberculosis; Pyrazinamide; Streptomycin; Tuberculosis; Tuberculosis, Pulmonary | 1963 |
RECENT ADVANCES IN TREATMENT OF ORGAN TUBERCULOSIS.
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Antitubercular Agents; Child; Cycloserine; Ethionamide; Isoniazid; Kanamycin; Mycobacterium Infections; Prednisone; Pyrazinamide; Streptomycin; Tuberculosis; Tuberculosis, Cardiovascular; Tuberculosis, Meningeal; Tuberculosis, Miliary; Tuberculosis, Osteoarticular; Tuberculosis, Pleural; Tuberculosis, Pulmonary; Tuberculosis, Urogenital; Viomycin | 1964 |
CHEMOTHERAPY FOR PATIENTS WITH CULTURES RESISTANT TO STREPTOMYCIN, ISONIAZID AND PAS.
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Cycloserine; Czechoslovakia; Drug Resistance; Drug Resistance, Microbial; Ethionamide; Isoniazid; Pyrazinamide; Streptomycin; Toxicology; Tuberculosis; Tuberculosis, Pulmonary; Viomycin | 1963 |
[SOME CLINICAL ASPECTS OF DRUG RESISTANCE OF TUBERCLE BACILLI ISOLATED FROM PATIENTS WITH FIBRO-CAVERNOUS TUBERCULOSIS].
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Bacillus; Culture Media; Drug Resistance; Drug Resistance, Microbial; Humans; Isoniazid; Mycobacterium tuberculosis; Pyrazinamide; Research; Tuberculosis; Tuberculosis, Pulmonary | 1963 |
[OUR RESULTS IN CHEMO-ANTIBIOTIC THERAPY OF SILICOTUBERCULOSIS].
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Anti-Bacterial Agents; Cycloserine; Ethionamide; Isoniazid; Kanamycin; Pyrazinamide; Silicotuberculosis; Streptomycin; Toxicology | 1963 |
SOME PROBLEMS IN THE MANAGEMENT OF TUBERCULOSIS.
Topics: Adolescent; Aminosalicylic Acid; Aminosalicylic Acids; Anti-Bacterial Agents; Antitubercular Agents; Child; Cycloserine; Drug Tolerance; Ethionamide; Isoniazid; Oxytetracycline; Pyrazinamide; Streptomycin; Tetracycline; Toxicology; Tuberculosis; Tuberculosis, Pulmonary; Viomycin | 1964 |
D-CYCLOSERINE IN THE TREATMENT OF PULMONARY TUBERCULOSIS RESISTANT TO THE STANDARD DRUGS: A STUDY OF 116 CASES.
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Cycloserine; Drug Resistance; Drug Resistance, Microbial; Ethionamide; Isoniazid; Pyrazinamide; Streptomycin; Toxicology; Tuberculosis; Tuberculosis, Pulmonary | 1964 |
[INTOLERANCE AND TOXICITY OF SUBSTITUTE ANTIBACTERIAL DRUGS].
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Anti-Bacterial Agents; Chemical and Drug Induced Liver Injury; Cycloserine; Ethionamide; Feeding and Eating Disorders; Hepatitis; Isoniazid; Joint Diseases; Kanamycin; Nausea; Psychoses, Substance-Induced; Psychotic Disorders; Pyrazinamide; Streptomycin; Toxicology; Vertigo; Viomycin | 1963 |
[ANTIMICROBIAL SCREEN IN PHTHISIOLOGICAL SURGERY].
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Anti-Infective Agents; Antitubercular Agents; Collapse Therapy; Cycloserine; Drug Resistance; Drug Resistance, Microbial; Ethionamide; Isoniazid; Pneumonectomy; Pyrazinamide; Streptomycin; Tuberculosis; Tuberculosis, Pulmonary; Viomycin | 1963 |
[BRONCHIAL FISTULAS; COLLECTIVE REVIEW AND PERSONAL OBSERVATIONS].
Topics: Adrenal Cortex Hormones; Bronchial Fistula; Epinephrine; Esophageal Fistula; Gastric Fistula; Humans; Intestinal Fistula; Isoniazid; Pneumonectomy; Pyrazinamide; Radiography, Thoracic; Streptomycin; Surgical Procedures, Operative | 1963 |
[ANTIBACTERIAL TREATMENT IN PATIENTS AFFLICTED WITH PULMONARY TUBERCULOSIS CAUSED BY MYCOBACTERIA RESISTANT TO THE MAJOR CHEMO-ANTIBIOTICS].
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Anti-Bacterial Agents; Antibiotics, Antitubercular; Collapse Therapy; Cycloserine; Drug Resistance; Drug Resistance, Microbial; Ethionamide; Isoniazid; Kanamycin; Pneumonectomy; Pyrazinamide; Streptomycin; Tuberculosis, Pulmonary | 1963 |
[THE RESULTS OBTAINED WITH THE COMBINATION OF PYRAZINAMIDE AND ISONIAZID IN THE TREATMENT OF PULMONARY TUBERCULOSIS].
Topics: Humans; Isoniazid; Pyrazinamide; Tuberculosis; Tuberculosis, Pulmonary | 1963 |
ANONYMOUS MYCOBACTERIA ISOLATED FROM CLINICAL SPECIMENS IN HONG KONG.
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Bacteriological Techniques; China; Drug Resistance; Drug Resistance, Microbial; Hong Kong; Humans; Isoniazid; Kanamycin; Mycobacterium; Mycobacterium tuberculosis; Pyrazinamide; Research; Streptomycin; Thiosemicarbazones | 1964 |
[TREATMENT OF TUBERCULOSIS AND DIABETES BECOMING SIMILAR].
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Cycloserine; Diabetes Mellitus; Ethionamide; Isoniazid; Pneumothorax; Pneumothorax, Artificial; Pyrazinamide; Streptomycin; Tuberculosis; Tuberculosis, Pulmonary | 1964 |
CLINICAL ASPECTS, MEDICAL AND SURGICAL, IN THE MANAGEMENT OF BATTEY-TYPE PULMONARY DISEASE.
Topics: Bronchiectasis; Calcification, Physiologic; Drug Resistance; Drug Resistance, Microbial; Epidemiology; Georgia; Humans; Isoniazid; Mycobacterium Infections; Pneumoconiosis; Pulmonary Atelectasis; Pulmonary Fibrosis; Pyrazinamide; Radiography, Thoracic; Streptomycin; Tuberculin Test; Tuberculosis; Tuberculosis, Pulmonary | 1964 |
ANTIMICROBIAL THERAPY OF PULMONARY TUBERCULOSIS.
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Anti-Infective Agents; Cycloserine; Dihydrostreptomycin Sulfate; Isoniazid; Pyrazinamide; Streptomycin; Toxicology; Tuberculosis; Tuberculosis, Pulmonary; Viomycin | 1963 |
INCIDENCE AND MANAGEMENT OF TUBERCULOUS STRICTURES OF THE URINARY TRACT.
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Constriction, Pathologic; Humans; Hydronephrosis; Incidence; Isoniazid; Nephrectomy; Pyrazinamide; Streptomycin; Surgical Procedures, Operative; Tuberculosis; Tuberculosis, Renal; Tuberculosis, Urogenital; Ureter; Urethral Stricture; Urinary Bladder Diseases; Urinary Catheterization; Urinary Diversion; Urography | 1964 |
[THE USE OF ANTIBACILLARY DRUGS].
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Cycloserine; Drug Resistance; Drug Resistance, Microbial; Ethionamide; Isoniazid; Kanamycin; Pneumonectomy; Pyrazinamide; Streptomycin; Tuberculosis; Tuberculosis, Pulmonary; Viomycin | 1964 |
A SPUTUM SURVEY OF CASES OF PULMONARY TUBERCULOSIS TWO TO THREE YEARS AFTER STARTING TREATMENT IN A RURAL AREA IN KENYA.
Topics: Child; Drug Resistance; Drug Resistance, Microbial; Health Surveys; Humans; Infant; Isoniazid; Kenya; Pyrazinamide; Rural Health; Sputum; Streptomycin; Tuberculosis; Tuberculosis, Pulmonary | 1964 |
[NEW COMBINATIONS OF ANTITUBERCULAR AGENTS IN THE TREATMENT OF RENAL TUBERCULOSIS].
Topics: Adolescent; Aminosalicylic Acid; Aminosalicylic Acids; Anti-Bacterial Agents; Antitubercular Agents; Cycloserine; Ethionamide; Isoniazid; Kanamycin; Nephrectomy; Nephritis; Pyrazinamide; Streptomycin; Toxicology; Tuberculosis; Tuberculosis, Renal; Tuberculosis, Urogenital; Viomycin | 1964 |
[THE TREATMENT OF TUBERCULOSIS WITH 2ND LINE DRUGS].
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Anti-Bacterial Agents; Antibiotics, Antitubercular; Cycloserine; Drug Resistance; Drug Resistance, Microbial; Ethionamide; Isoniazid; Kanamycin; Pyrazinamide; Streptomycin; Toxicology; Tuberculosis; Tuberculosis, Pulmonary; Viomycin | 1964 |
[ANTIMICROBIAL TREATMENT OF TUBERCULOSIS WITH SUBSIDIARY DRUGS. 2ND LINE DRUGS].
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Anti-Infective Agents; Antitubercular Agents; Bacteriology; Cycloserine; Drug Resistance; Drug Resistance, Microbial; Ethionamide; Isoniazid; Kanamycin; Phenylthiourea; Pyrazinamide; Statistics as Topic; Streptomycin; Toxicology; Tuberculosis; Tuberculosis, Pulmonary; Viomycin | 1964 |
PULMONARY TUBERCULOSIS.
Topics: Adrenal Cortex Hormones; Aminosalicylic Acid; Aminosalicylic Acids; Child; Cycloserine; Drug Resistance; Drug Resistance, Microbial; Ethambutol; Ethionamide; Isoniazid; Kanamycin; Mycobacterium Infections; Pharmacology; Prognosis; Pyrazinamide; Streptomycin; Surgical Procedures, Operative; Thiosemicarbazones; Toxicology; Tuberculosis; Tuberculosis, Miliary; Tuberculosis, Pulmonary; Viomycin | 1964 |
A STUDY OF THE INFLUENCE OF THE ISONIAZID INACTIVATOR PHENOTYPE ON REVERSION IN GENITO-URINARY TUBERCULOSIS.
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Bacteriology; Genetics, Medical; Geriatrics; Isoniazid; Metabolism; Phenotype; Pyrazinamide; Streptomycin; Thiosemicarbazones; Toxicology; Tuberculosis; Tuberculosis, Urogenital; Urine | 1964 |
A CONTROLLED COMPARISON OF STREPTOMYCIN PLUS PYRAZINAMIDE AND STREPTOMYCIN PLUS PAS IN THE RETREATMENT OF PATIENTS EXCRETING ISONIAZID-RESISTANT ORGANISMS.
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Bacteriology; Biomedical Research; Drug Resistance; Drug Resistance, Microbial; India; Isoniazid; Pyrazinamide; Retreatment; Sputum; Streptomycin; Toxicology; Tuberculosis; Tuberculosis, Pulmonary | 1964 |
TREATMENT OF PATIENTS WITH CULTURES RESISTANT TO THE PRIMARY ANTI-TUBERCULOSIS DRUGS.
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Antitubercular Agents; Bacteriological Techniques; Biomedical Research; Cycloserine; Drug Resistance; Drug Resistance, Microbial; Ethionamide; Isoniazid; Poland; Pyrazinamide; Sputum; Streptomycin; Toxicology; Tuberculosis; Tuberculosis, Pulmonary | 1964 |
[LUNG TUBERCULOMAS].
Topics: Adolescent; Anti-Bacterial Agents; Antibiotics, Antitubercular; Antitubercular Agents; Bronchoscopy; Collapse Therapy; Humans; Isoniazid; Pyrazinamide; Radiography, Thoracic; Tuberculoma; Tuberculosis; Tuberculosis, Pulmonary | 1963 |
[APROPOS OF ETHIONAMIDE JAUNDICE].
Topics: Alanine Transaminase; Alcoholism; Aminosalicylic Acid; Aminosalicylic Acids; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Child; Diabetes Mellitus; Ethionamide; Hepatitis; Hepatitis A; Isoniazid; Jaundice; Liver Cirrhosis; Pyrazinamide; Pyridoxine; Streptomycin; Toxicology; Tuberculosis; Tuberculosis, Pulmonary | 1964 |
RESPONSE TO TREATMENT IN SILICOTUBERCULOSIS; A TEN-YEAR SURVEY.
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Cycloserine; Drug Therapy; Ethionamide; Isoniazid; Pyrazinamide; Silicotuberculosis; Statistics as Topic; Viomycin | 1964 |
[DRUG TREATMENT OF RENAL TUBERCULOSIS].
Topics: Adrenal Cortex Hormones; Aminosalicylic Acid; Aminosalicylic Acids; Antitubercular Agents; Cycloserine; Dihydrostreptomycin Sulfate; Ethambutol; Ethionamide; Humans; Isoniazid; Kanamycin; Oxytetracycline; Phenylthiourea; Pyrazinamide; Streptomycin; Thiosemicarbazones; Tuberculosis; Tuberculosis, Renal; Viomycin | 1964 |
[INDICATIONS AND UTILITY OF INTRATHECAL AND INTRAVENTRICULAR TREATMENT IN THE THERAPY OF TUBERCULAR MENINGITIS].
Topics: Child; Chlorpromazine; Humans; Injections; Injections, Spinal; Isoniazid; Prednisolone; Pyrazinamide; Streptomycin; Tuberculosis; Tuberculosis, Meningeal | 1963 |
TREATMENT OF TUBERCULOSIS OF THE KNEE.
Topics: Adolescent; Aminosalicylic Acid; Aminosalicylic Acids; Child; Drug Therapy; Ethionamide; Humans; Isoniazid; Knee Joint; Pyrazinamide; Radiography; Streptomycin; Surgical Procedures, Operative; Toxicology; Tuberculosis; Tuberculosis, Osteoarticular; Viomycin | 1964 |
[CHEMO-ANTIBIOTIC THERAPY OF TUBERCULOSIS IN DIABETICS AND ITS REPERCUSSIONS ON GLUCIDE METABOLISM].
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Antitubercular Agents; Blood Glucose; Carbohydrate Metabolism; Cycloserine; Diabetes Mellitus; Drug Tolerance; Ethionamide; Humans; Isoniazid; Kanamycin; Pharmacology; Pyrazinamide; Rifamycins; Streptomycin; Thiosemicarbazones; Tuberculosis; Tuberculosis, Pulmonary | 1964 |
ALTERNATING REGIMENS OF STREPTOMYCIN-PYAZINAMIDE, ISONIAZID-PARA-AMINOSALICYLIC ACID AT BATTEY STATE HOSPITAL.
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Drug Resistance; Drug Resistance, Microbial; Drug Therapy; Hospitals, State; Isoniazid; Pyrazinamide; Streptomycin; Tuberculosis; Tuberculosis, Pulmonary | 1964 |
[COMPARISON OF CULTURE AND BIOCHEMICAL METHODS FOR THE DIFFERENTIATION OF MYCOBACTERIUM TUBERCULOSIS AND MYCOBACTERIUM BOVIS WITH SPECIAL REFERENCE TO STRAINS WITH HIGH ISONIAZID RESISTANCE].
Topics: Cell Differentiation; Culture Media; Drug Resistance, Microbial; Isoniazid; Mycobacterium bovis; Mycobacterium tuberculosis; Niacin; Nicotinic Acids; Nitrates; Oxidoreductases; Pyrazinamide; Research | 1964 |
INFECTION OF MICE WITH MYCOBACTERIUM TUBERCULOSIS, STRAIN H37RA.
Topics: Animals; Isoniazid; Lung; Mice; Mycobacterium bovis; Mycobacterium tuberculosis; Pharmacology; Pyrazinamide; Research; Spleen; Tuberculosis; Tuberculosis Vaccines; Tuberculosis, Pulmonary | 1964 |
[ENZYMATIC STUDY OF THE LIVER IN PULMONARY TUBERCULOSIS. RESEARCH ON A POSSIBLE HEPATOTOXIC EFFECT OF ANTIBACTERIAL MEDICATIONS].
Topics: Alanine Transaminase; Aminosalicylic Acid; Aminosalicylic Acids; Anti-Bacterial Agents; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Ethionamide; Fructose-Bisphosphatase; Hepatitis A; Isoniazid; Liver; Liver Function Tests; Nucleotidases; Oxidoreductases; Pyrazinamide; Sorbitol; Streptomycin; Toxicology; Tuberculosis; Tuberculosis, Pulmonary | 1964 |
REACTIONS TO ANTITUBERCULOSIS DRUGS AMONG CHINESE IN HONG KONG.
Topics: Alcoholism; Alopecia; Aminosalicylic Acid; Aminosalicylic Acids; Antitubercular Agents; Asian People; Chemical and Drug Induced Liver Injury; China; Dermatitis, Exfoliative; Drug Therapy; Ethionamide; Hepatitis A; Hong Kong; Isoniazid; Jaundice; Phenylthiourea; Psychoses, Substance-Induced; Psychotic Disorders; Pyrazinamide; Streptomycin; Toxicology | 1964 |
CHEMOTHERAPY OF PREVIOUSLY TREATED PATIENTS WITH PULMONARY TUBERCULOSIS.
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Cycloserine; Drug Hypersensitivity; Drug Resistance; Drug Resistance, Microbial; Ethionamide; Isoniazid; Pyrazinamide; Sputum; Streptomycin; Toxicology; Tuberculosis; Tuberculosis, Pulmonary; Yugoslavia | 1964 |
POTT'S DISEASE TREATED WITHOUT SPINAL FUSION.
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Antitubercular Agents; Drug Therapy; Humans; Isoniazid; Prognosis; Pyrazinamide; Radiography; Spinal Fusion; Streptomycin; Tuberculosis; Tuberculosis, Spinal | 1964 |
RE-TREATMENT OF DRUG-RESISTANT PULMONARY TUBERCULOSIS AT BATTEY STATE HOSPITAL.
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Cycloserine; Drug Resistance; Drug Resistance, Microbial; Drug Therapy; Ethambutol; Ethionamide; Geriatrics; Hospitals, State; Isoniazid; Kanamycin; Pyrazinamide; Streptomycin; Toxicology; Tuberculosis; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Viomycin | 1964 |
A PRELIMINARY REPORT ON A NEW ANTITUBERCULOUS DRUG 4-AMINO-2-HYDROXY-PHENYL-1, 3, 4,-OXADIAZOL-2-OL WS 127.
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Antitubercular Agents; Biomedical Research; Blood; Cycloserine; Drug Resistance; Drug Resistance, Microbial; Ethionamide; Isoniazid; Mice; Oxadiazoles; Pharmacology; Pneumothorax; Pneumothorax, Artificial; Pyrazinamide; Radiography, Thoracic; Sputum; Streptomycin; Toxicology; Tuberculosis; Tuberculosis, Pulmonary; Urine | 1964 |
SPUTUM CONVERSION IN CHRONIC TUBERCULOSIS WITH POLYRESISTANT BACILLI.
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Antitubercular Agents; Bacillus; Cycloserine; Dihydrostreptomycin Sulfate; Drug Resistance; Drug Resistance, Microbial; Drug Therapy; Ethionamide; Geriatrics; Isoniazid; Kanamycin; Pyrazinamide; Sputum; Streptomycin; Thiosemicarbazones; Toxicology; Tuberculosis; Viomycin | 1964 |
ANTITUBERCULOUS DRUGS AND SIDEROBLASTIC ANAEMIA.
Topics: Adolescent; Aminosalicylic Acid; Aminosalicylic Acids; Anemia; Anemia, Hypochromic; Anemia, Sideroblastic; Cycloserine; Drug Therapy; Geriatrics; Hematologic Diseases; Isoniazid; Pyrazinamide; Streptomycin; Toxicology; Tuberculosis; Tuberculosis, Pulmonary | 1965 |
EXPERIMENTAL SIDEROBLASTIC ANAEMIA.
Topics: Aminopterin; Aminosalicylic Acid; Aminosalicylic Acids; Anemia; Anemia, Hypochromic; Anemia, Sideroblastic; Bone Marrow Examination; Cycloserine; Folic Acid; Guinea Pigs; Hemoglobins; Isoniazid; Mice; Pharmacology; Pyrazinamide; Pyridoxine; Research; Toxicology; Vitamin B 6 Deficiency | 1965 |
[TUBERCULOUS MENINGITIS WITH RESISTANT KOCH BACILLI; RECOVERY OWING TO CYCLOSERINE-PYRAZINAMIDE COMBINATION].
Topics: Adolescent; Aminosalicylic Acid; Aminosalicylic Acids; Cycloserine; Drug Resistance; Drug Resistance, Microbial; Drug Synergism; Drug Therapy; Ethionamide; Humans; Isoniazid; Kanamycin; Mycobacterium tuberculosis; Pyrazinamide; Streptomycin; Tuberculosis; Tuberculosis, Meningeal | 1964 |
DRUG RESISTANCE IN PULMONARY TUBERCULOSIS; TREATMENT WITH ETHIONAMIDE IN VARIOUS DRUG COMBINATIONS.
Topics: Cycloserine; Drug Combinations; Drug Resistance; Drug Resistance, Microbial; Drug Therapy; Drug Tolerance; Ethionamide; Isoniazid; Kanamycin; Pyrazinamide; Toxicology; Tuberculosis; Tuberculosis, Pulmonary; Viomycin | 1965 |
CHEMOTHERAPY OF TUBERCULOSIS.
Topics: Adrenal Cortex Hormones; Aminosalicylic Acid; Aminosalicylic Acids; Antitubercular Agents; Classification; Cycloserine; Drug Therapy; Ethionamide; Isoniazid; Kanamycin; Oxytetracycline; Pyrazinamide; Rest; Social Isolation; Streptomycin; Surgical Procedures, Operative; Thiosemicarbazones; Toxicology; Tuberculosis; Viomycin | 1964 |
RENAL CALCIFICATION IN GENITO-URINARY TUBERCULOSIS.
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Drug Therapy; Isoniazid; Nephrectomy; Nephrocalcinosis; Pyrazinamide; Streptomycin; Thiosemicarbazones; Tuberculosis; Tuberculosis, Urogenital; Urine; Viomycin | 1965 |
THE USE OF ETHIONAMIDE IN COMBINED DRUG REGIMENS IN THE RE-TREATMENT OF ISONIAZID-RESISTANT PULMONARY TUBERCULOSIS.
Topics: Adolescent; Aminosalicylic Acid; Aminosalicylic Acids; Antitubercular Agents; Cycloserine; Drug Resistance; Drug Resistance, Microbial; Drug Therapy; Ethionamide; Hepatomegaly; Isoniazid; Kanamycin; Liver Function Tests; Pharmacology; Pyrazinamide; Toxicology; Tuberculosis; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Viomycin | 1965 |
A CONTROLLED CLINICAL TRIAL OF ETHIONAMIDE, CYCLOSERINE AND PYRAZINAMIDE IN PREVIOUSLY TREATED PATIENTS WITH PULMONARY TUBERCULOSIS.
Topics: Cycloserine; Drug Therapy; Ethionamide; Isoniazid; Pyrazinamide; Radiography, Thoracic; Streptomycin; Toxicology; Tuberculosis; Tuberculosis, Pulmonary | 1965 |
Clinical experience with PZA-INH therapy: report on study of resected specimens following the above therapy in particular.
Topics: Humans; Isoniazid; Pyrazinamide | 1959 |
Effect of pyrazinamide on antimicrobially active serum isoniazid.
Topics: Anti-Infective Agents; Humans; Isoniazid; Pyrazinamide | 1960 |
[Primary pulmonary tuberculosis treated with pyrazinamide. Immediate clinical and radiological results and results after prolonged treatment with streptomycin and isoniazid].
Topics: Humans; Isoniazid; Pyrazinamide; Radiology; Streptomycin; Tuberculosis, Pulmonary | 1959 |
[Elimination of alpha-ketone acids after the administration of pyrazinamide, of TH-1314 and of isoniazid].
Topics: Biological Transport; Body Fluids; Humans; Isoniazid; Keto Acids; Ketones; Pyrazinamide | 1962 |
[Combined therapy of massive doses of isoniazid, pyrazinamide, and sulfisoxazole for patients with pulmonary tuberculosis resistant to streptomycin, paraaminosalicylic acid, and isoniazid].
Topics: Aminosalicylic Acid; Humans; Isoniazid; Psychotherapy, Multiple; Pyrazinamide; Streptomycin; Sulfanilamide; Sulfanilamides; Sulfisoxazole; Sulfonamides; Tuberculosis; Tuberculosis, Pulmonary | 1961 |
[A clinical study on tuberculosis among young adults in Japan: analysis on patients admitted to national hospitals in Kanto- and Kinki-areas in the year 2000].
Topics: Adult; Age Factors; Antitubercular Agents; Drug Resistance, Bacterial; Female; Hospitals, Public; Humans; Inpatients; Isoniazid; Japan; Length of Stay; Male; Mycobacterium tuberculosis; Pyrazinamide; Severity of Illness Index; Sputum; Time Factors; Transients and Migrants; Tuberculosis, Pulmonary | 2003 |
Poly (DL-lactide-co-glycolide) nanoparticle-based inhalable sustained drug delivery system for experimental tuberculosis.
Topics: Administration, Inhalation; Aerosols; Animals; Antibiotics, Antitubercular; Antitubercular Agents; Area Under Curve; Biological Availability; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemistry, Physical; Colony Count, Microbial; Drug Carriers; Drug Combinations; Drug Compounding; Female; Guinea Pigs; Half-Life; Injections, Intravenous; Isoniazid; Lactic Acid; Lung; Male; Microspheres; Mycobacterium tuberculosis; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Pyrazinamide; Rifampin; Tuberculosis | 2003 |
[Characteristics and treatment outcomes of INH-resistant or RFP-resistant tuberculosis].
Topics: Adult; Aged; Antitubercular Agents; Cohort Studies; Drug Therapy, Combination; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Retrospective Studies; Rifampin; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 2003 |
Nanoparticle encapsulated antitubercular drugs as a potential oral drug delivery system against murine tuberculosis.
Topics: Administration, Oral; Animals; Antitubercular Agents; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Female; Glycolates; Isoniazid; Lactic Acid; Liver; Lung; Male; Mice; Mycobacterium tuberculosis; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Pyrazinamide; Rifampin; Spleen; Tuberculosis | 2003 |
Relative versus absolute noncontagiousness of respiratory tuberculosis on treatment.
Topics: Academic Medical Centers; Adult; Alberta; Antibiotics, Antitubercular; Antitubercular Agents; Colony Count, Microbial; Disease Progression; Female; Humans; Isoniazid; Male; Middle Aged; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Risk Factors; Sputum; Time Factors; Tuberculosis, Pulmonary | 2003 |
Mycobacterium tuberculosis infection following allogeneic peripheral blood stem cell transplantation.
Topics: Adult; Anemia, Aplastic; Antitubercular Agents; Drug Therapy, Combination; Humans; Immunocompromised Host; Isoniazid; Male; Mycobacterium tuberculosis; Peripheral Blood Stem Cell Transplantation; Pyrazinamide; Tuberculosis | 2003 |
[Severe course and contingent risk factors in optic neuropathy and myelopathy after tuberculostatics].
Topics: Adult; Antitubercular Agents; Disease Progression; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Male; Optic Nerve Diseases; Photophobia; Pyrazinamide; Rifampin; Risk Factors; Risk Management; Spinal Cord Diseases; Treatment Outcome; Tuberculosis, Lymph Node | 2003 |
Bioavailability of rifampicin following concomitant administration of ethambutol or isoniazid or pyrazinamide or a combination of the three drugs.
Topics: Adolescent; Adult; Antibiotics, Antitubercular; Area Under Curve; Body Weight; Ethambutol; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Staphylococcus aureus; Time Factors | 2003 |
Multidrug-resistant Mycobacterium tuberculosis in HIV-infected persons, Peru.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antitubercular Agents; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Ethambutol; Female; HIV Infections; Humans; Interviews as Topic; Isoniazid; Male; Microbial Sensitivity Tests; Middle Aged; Mycobacterium tuberculosis; Peru; Prevalence; Pyrazinamide; Rifampin; Tuberculosis, Multidrug-Resistant | 2003 |
[Septic loosening of a Wagner revision stem provoked by Mycobacterium tuberculosis].
Topics: Acetabulum; Aged; Antibiotics, Antitubercular; Antitubercular Agents; Arthroplasty, Replacement, Hip; Ethambutol; Follow-Up Studies; Humans; Isoniazid; Male; Mycobacterium tuberculosis; Prosthesis Failure; Prosthesis-Related Infections; Pyrazinamide; Radioimmunoassay; Reoperation; Rifampin; Synovial Fluid; Time Factors; Titanium; Tuberculosis | 2003 |
Pancytopenia due to extensive hemophagocytosis following anti-tubercular treatment.
Topics: Adult; Antitubercular Agents; Biopsy, Needle; Bone Marrow; Hepatomegaly; Histiocytosis; Humans; Isoniazid; Male; Pancytopenia; Pyrazinamide; Rifampin; Tuberculosis | 2004 |
Cavitatory pulmonary tuberculosis in a 52-day-old infant.
Topics: Antibiotics, Antitubercular; Antitubercular Agents; Asia; Drug Therapy, Combination; Female; Humans; Infant; Infectious Disease Transmission, Vertical; Isoniazid; Male; Pregnancy; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Pulmonary | 2004 |
Retrovesical tuberculosis.
Topics: Anti-Bacterial Agents; Antitubercular Agents; Biopsy, Fine-Needle; Child; Combined Modality Therapy; Drug Therapy, Combination; Ethambutol; Fever; Humans; Isoniazid; Laparotomy; Male; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Tomography, X-Ray Computed; Tuberculoma; Tuberculosis, Urogenital; Ultrasonography, Interventional; Urination Disorders | 2004 |
[Unexpected complication in an elderly lady suffering from rheumatoid arthritis].
Topics: Aged; Antibiotics, Antitubercular; Antitubercular Agents; Arthritis, Rheumatoid; Diagnosis, Differential; Female; Follow-Up Studies; Humans; Isoniazid; Mycobacterium tuberculosis; Pyrazinamide; Pyridoxine; Radiography, Abdominal; Rifampin; Time Factors; Tomography, X-Ray Computed; Treatment Outcome; Tuberculosis, Urogenital; Urine | 2004 |
Cranial-epidural tuberculosis presenting as a scalp swelling.
Topics: Adult; Antitubercular Agents; Biopsy; Diagnosis, Differential; Drug Therapy, Combination; Edema; Epidural Space; Ethambutol; Frontal Bone; Humans; Isoniazid; Magnetic Resonance Imaging; Male; Parietal Bone; Pyrazinamide; Rifampin; Scalp; Tomography, X-Ray Computed; Tuberculosis, Osteoarticular | 2004 |
Subcutaneous nanoparticle-based antitubercular chemotherapy in an experimental model.
Topics: Animals; Antibiotics, Antitubercular; Antitubercular Agents; Biological Availability; Drug Combinations; Drug Compounding; Injections, Subcutaneous; Isoniazid; Lactic Acid; Lung; Mice; Microspheres; Mycobacterium tuberculosis; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Pyrazinamide; Rifampin; Spleen; Tissue Distribution; Tuberculosis | 2004 |
Completing tuberculosis prophylaxis in jail: targeting treatment and comparison of rifampin/pyrazinamide with isoniazid regimens.
Topics: Antitubercular Agents; Carrier State; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Isoniazid; Male; Patient Compliance; Prisons; Pyrazinamide; Retrospective Studies; Rifampin; Tuberculosis | 2004 |
Characteristics and outcome of tuberculosis patients whose sputum smears are positive at or after 5 months of treatment.
Topics: Adult; Antitubercular Agents; Ethambutol; Female; Follow-Up Studies; Health Surveys; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Sputum; Time Factors; Treatment Outcome; Tuberculosis, Pulmonary | 2004 |
Drug resistance trends among previously treated tuberculosis patients in a national registry in Peru, 1994-2001.
Topics: Antitubercular Agents; Drug Resistance, Multiple, Bacterial; Ethambutol; Humans; Isoniazid; Peru; Pyrazinamide; Registries; Retrospective Studies; Rifampin; Streptomycin; Treatment Outcome; Tuberculosis | 2004 |
Antituberculosis drugs and hepatotoxicity.
Topics: Antitubercular Agents; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Humans; Isoniazid; Pyrazinamide; Rifampin; Risk Factors; Tuberculosis | 2004 |
Prescriptions and dosages of anti-tuberculosis drugs in the National Tuberculosis Control Programme of Malawi.
Topics: Administration, Oral; Adult; Antibiotics, Antitubercular; Antitubercular Agents; Body Weight; Communicable Disease Control; Drug Therapy, Combination; Drug Utilization Review; Ethambutol; Female; Guideline Adherence; Hospital Records; Hospitals, Public; Humans; Isoniazid; Malawi; Male; Middle Aged; Pyrazinamide; Registries; Rifampin; Tuberculosis, Pulmonary | 2004 |
A 32-year-old man with tuberculosis, fever, and rash.
Topics: Adult; Antitubercular Agents; Diagnosis, Differential; Drug Hypersensitivity; Ethambutol; Exanthema; Fever; Humans; Isoniazid; Liver; Liver Failure; Male; Pyrazinamide; Pyridoxine; Rifampin; Skin; Tuberculosis, Pulmonary | 2004 |
Tuberculous epididymitis with extensive retroperitoneal and mediastinal involvement.
Topics: Adult; Antitubercular Agents; Diagnostic Imaging; District of Columbia; Drug Therapy, Combination; Epididymitis; Humans; Isoniazid; Male; Mediastinum; Pyrazinamide; Retroperitoneal Space; Rifampin; Sierra Leone; Tuberculosis, Male Genital | 2004 |
[Scrofuloderma. a clinical case].
Topics: Antibiotics, Antitubercular; Child; Drug Therapy, Combination; Female; Humans; Isoniazid; Mycobacterium tuberculosis; Pyrazinamide; Tuberculosis, Cutaneous | 2004 |
Anaerobic incubation conditions enhance pyrazinamide activity against Mycobacterium tuberculosis.
Topics: Adenosine Triphosphatases; Anaerobiosis; Antitubercular Agents; Colony Count, Microbial; Electron Transport; Energy Metabolism; Enzyme Inhibitors; Isoniazid; Mycobacterium tuberculosis; Nitrates; Oxygen; Pyrazinamide; Rifampin | 2004 |
Standardization of the method for estimation of ethambutol in pharmaceutical preparations and biological fluid.
Topics: Antitubercular Agents; Chemistry, Clinical; Chromatography; Dose-Response Relationship, Drug; Ethambutol; HIV Seropositivity; Humans; Isoniazid; Pharmaceutical Preparations; Pyrazinamide; Reference Standards; Reproducibility of Results; Resins, Synthetic; Sensitivity and Specificity; Time Factors | 2004 |
Cervical spine tuberculosis.
Topics: Adolescent; Antitubercular Agents; Cervical Vertebrae; Ethambutol; Humans; Isoniazid; Male; Pyrazinamide; Radiography; Rifampin; Treatment Outcome; Tuberculosis, Spinal | 2004 |
[Efficiency of an intensive stage of chemotherapy for tuberculosis in elderly and senile patients].
Topics: Age Factors; Aged; Aged, 80 and over; Antibiotics, Antitubercular; Antitubercular Agents; Diabetes Complications; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Risk Factors; Sex Factors; Sputum; Tuberculosis, Pulmonary; World Health Organization | 2004 |
[Bactericidal therapy in patients with tuberculosis].
Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Antitubercular Agents; Chlortetracycline; Drug Resistance, Bacterial; Drug Therapy, Combination; Female; Humans; Infusions, Intravenous; Injections, Intramuscular; Isoniazid; Kanamycin; Male; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Pyrazinamide; Recurrence; Rifampin; Streptomycin; Time Factors; Tuberculosis, Pulmonary | 2004 |
[Experimental evidence for Mycobacterium tuberculosis persistence in M. tuberculosis-infected H37RV mice in the treatment with 3 first-line drugs (rifampicin, isoniazid, pyrazinamide)].
Topics: Animals; Antibiotics, Antitubercular; Antitubercular Agents; Disease Models, Animal; DNA, Bacterial; Drug Therapy, Combination; Isoniazid; Mice; Mice, Inbred BALB C; Mycobacterium tuberculosis; Polymerase Chain Reaction; Pyrazinamide; Rifampin; Time Factors; Tuberculosis | 2004 |
Tuberculosis: medical management update.
Topics: Adult; Antitubercular Agents; Child; Dental Staff; Ethambutol; Humans; Infectious Disease Transmission, Patient-to-Professional; Isoniazid; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Tuberculosis, Oral; Tuberculosis, Pulmonary | 2004 |
Hepatotoxicity of rifampin-pyrazinamide and isoniazid preventive therapy and tuberculosis treatment.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Antibiotics, Antitubercular; Chemical and Drug Induced Liver Injury; Cohort Studies; Drug Therapy, Combination; Female; Humans; Isoniazid; Male; Middle Aged; Netherlands; Prospective Studies; Pyrazinamide; Retrospective Studies; Rifampin; Treatment Outcome; Tuberculosis | 2004 |
Hepatotoxicity of rifampin and pyrazinamide in the treatment of latent tuberculosis infection in HIV-infected persons: is it different than in HIV-uninfected persons?
Topics: Adolescent; Adult; Aspartate Aminotransferases; Bilirubin; Chemical and Drug Induced Liver Injury; Drug Administration Schedule; Female; HIV Infections; Humans; Isoniazid; Liver; Male; Middle Aged; Multicenter Studies as Topic; Multivariate Analysis; Pyrazinamide; Randomized Controlled Trials as Topic; Regression Analysis; Rifampin; Tuberculosis | 2004 |
Multifocal osteoarticular tuberculosis: a case report.
Topics: Adult; Antitubercular Agents; Ethambutol; Female; Humans; Isoniazid; Joints; Magnetic Resonance Imaging; Pyrazinamide; Rifampin; Tomography, X-Ray Computed; Treatment Outcome; Tuberculosis, Osteoarticular | 2005 |
Rapid, automated, nonradiometric susceptibility testing of Mycobacterium tuberculosis complex to four first-line antituberculous drugs used in standard short-course chemotherapy.
Topics: Antitubercular Agents; Colony Count, Microbial; Culture Media; Drug Resistance, Multiple, Bacterial; Ethambutol; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Sampling Studies; Sensitivity and Specificity; Tuberculosis, Multidrug-Resistant | 2004 |
Efficacy and safety of Efavirenz in HIV patients on Rifampin for tuberculosis.
Topics: Adult; Alkynes; Anti-HIV Agents; Antibiotics, Antitubercular; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cohort Studies; Cyclopropanes; Drug Interactions; Female; HIV Infections; Humans; Isoniazid; Male; Middle Aged; Oxazines; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 2004 |
The effect of initial drug resistance on treatment response and acquired drug resistance during standardized short-course chemotherapy for tuberculosis.
Topics: Antitubercular Agents; Directly Observed Therapy; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Pyrazinamide; Retrospective Studies; Rifampin; Siberia; Tuberculosis, Pulmonary | 2004 |
The transpedicular approach in the management of thoracic spine tuberculosis: a short-term follow up study.
Topics: Abscess; Adolescent; Adult; Aged; Antitubercular Agents; Braces; Combined Modality Therapy; Curettage; Debridement; Decompression, Surgical; Disease Progression; Drainage; Ethambutol; Female; Follow-Up Studies; Humans; Immobilization; Isoniazid; Kyphosis; Male; Middle Aged; Movement Disorders; Pyrazinamide; Radiography; Recovery of Function; Retrospective Studies; Rifampin; Severity of Illness Index; Spinal Cord Compression; Thoracic Vertebrae; Treatment Outcome; Tuberculosis, Spinal | 2004 |
Successful kidney re-transplantation in a patient with previous allograft kidney tuberculosis.
Topics: Adult; Antitubercular Agents; Ethambutol; Humans; Immunosuppression Therapy; Isoniazid; Kidney Transplantation; Male; Opportunistic Infections; Pyrazinamide; Reoperation; Rifampin; Tuberculosis, Renal | 2004 |
Tuberculosis control and the private health sector in Bolivia: a survey of pharmacies.
Topics: Antitubercular Agents; Bolivia; Communicable Disease Control; Community Pharmacy Services; Cooperative Behavior; Drug Prescriptions; Ethambutol; Humans; Isoniazid; Pharmacies; Prescription Fees; Private Sector; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 2004 |
[Case of pulmonary tuberculosis in late stage of pregnancy].
Topics: Adult; Antitubercular Agents; Cesarean Section; Cross Infection; Drug Therapy, Combination; Ethambutol; Female; Hospitals, General; Humans; Infant, Newborn; Infection Control; Isoniazid; Patient Isolation; Pregnancy; Pregnancy Complications, Infectious; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 2004 |
Melatonin prevents the free radical and MADD metabolic profiles induced by antituberculosis drugs in an animal model.
Topics: Animals; Antioxidants; Antitubercular Agents; Carboxylic Acids; Death Domain Receptor Signaling Adaptor Proteins; Drug Combinations; Free Radicals; Guanine Nucleotide Exchange Factors; Hydroxybenzoates; Isoniazid; Melatonin; Oxidative Stress; Pyrazinamide; Rats; Rats, Sprague-Dawley; Rifampin | 2005 |
Treatment outcome of new culture positive pulmonary tuberculosis in Norway.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Child; Child, Preschool; Cohort Studies; Drug Resistance, Microbial; Drug Therapy, Combination; Ethambutol; Female; Humans; Infant; Infant, Newborn; Isoniazid; Male; Middle Aged; Mycobacterium tuberculosis; Norway; Patient Compliance; Pyrazinamide; Registries; Rifampin; Treatment Failure; Treatment Outcome; Tuberculosis, Pulmonary | 2005 |
[Effectiveness of an intensive chemotherapy stage in new cases of pulmonary tuberculosis and diabetes mellitus].
Topics: Antibiotics, Antitubercular; Antitubercular Agents; Data Interpretation, Statistical; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Humans; Isoniazid; Male; Mycobacterium tuberculosis; Pyrazinamide; Radiography, Thoracic; Rifampin; Time Factors; Tuberculosis, Pulmonary | 2004 |
A woman with a long history of abdominal pain.
Topics: Abdominal Pain; Adult; Antitubercular Agents; Cecal Diseases; Crohn Disease; Diagnosis, Differential; Drug Therapy, Combination; Ethambutol; Female; Humans; Ileal Diseases; Intestinal Obstruction; Isoniazid; Pyrazinamide; Radiography; Time Factors; Treatment Outcome; Tuberculosis, Gastrointestinal | 2004 |
Treatment outcome of multidrug-resistant tuberculosis among Vietnamese immigrants.
Topics: Capreomycin; Cycloserine; Drug Therapy, Combination; Emigration and Immigration; Ethambutol; Ethionamide; Female; Humans; Isoniazid; Male; Middle Aged; Ofloxacin; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Vietnam | 2005 |
Completing tuberculosis prophylaxis in jail: targeting treatment and a comparison of rifampin/pyrazinamide with isoniazid regimens.
Topics: Antibiotics, Antitubercular; Antitubercular Agents; Drug Therapy, Combination; Humans; Isoniazid; Prisons; Pyrazinamide; Rifampin; Tuberculosis | 2005 |
Optimal latent TB control methods.
Topics: Antitubercular Agents; Drug Therapy, Combination; Humans; Isoniazid; Pyrazinamide; Rifampin; Tuberculosis | 2005 |
Multifocal osteoarticular tuberculosis.
Topics: Adult; Antitubercular Agents; Bone and Bones; Combined Modality Therapy; Drug Therapy, Combination; Ethambutol; Fever; Humans; Isoniazid; Knee; Male; Pain; Pyrazinamide; Radiography; Radius; Rifampin; Treatment Outcome; Tuberculosis, Osteoarticular; Weight Loss; Wrist | 2005 |
Inactive hepatitis B surface antigen carrier state and hepatotoxicity during antituberculosis chemotherapy.
Topics: Adult; Antitubercular Agents; Carrier State; Case-Control Studies; Chemical and Drug Induced Liver Injury; Ethambutol; Female; Hepatitis B; Hepatitis B Surface Antigens; Humans; Incidence; Isoniazid; Male; Pyrazinamide; Retrospective Studies; Rifampin; Risk Factors | 2005 |
Solid lipid particle-based inhalable sustained drug delivery system against experimental tuberculosis.
Topics: Administration, Inhalation; Animals; Antitubercular Agents; Area Under Curve; Biological Availability; Drug Carriers; Drug Delivery Systems; Guinea Pigs; Isoniazid; Lipids; Nanostructures; Pyrazinamide; Rifampin; Tuberculosis | 2005 |
Protective effect of a 50% hydroalcoholic fruit extract of Emblica officinalis against anti-tuberculosis drugs induced liver toxicity.
Topics: Animals; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Fruit; Hepatocytes; Humans; Isoniazid; Male; Phyllanthus emblica; Phytotherapy; Plant Extracts; Protective Agents; Pyrazinamide; Rats; Rats, Wistar; Rifampin; Tuberculosis, Pulmonary | 2005 |
[Medicine and television: a diagnosis history].
Topics: Adult; Antitubercular Agents; Cholestasis, Intrahepatic; Diagnostic Errors; Hepatitis B; Hepatitis C; HIV Infections; Humans; Isoniazid; Male; Medicine in the Arts; Mercury Poisoning; Pyrazinamide; Rifampin; Television; Tuberculosis | 2005 |
Mechanistic explanation to the catalysis by pyrazinamide and ethambutol of reaction between rifampicin and isoniazid in anti-TB FDCs.
Topics: Amides; Antibiotics, Antitubercular; Antitubercular Agents; Catalysis; Chromatography, High Pressure Liquid; Drug Combinations; Ethambutol; Isoniazid; Picolinic Acids; Pyrazinamide; Rifampin; Spectrophotometry, Ultraviolet | 2005 |
Serum concentrations of antimycobacterial drugs in patients with pulmonary tuberculosis in Botswana.
Topics: Adult; Antitubercular Agents; Botswana; Comorbidity; Ethambutol; Female; HIV Infections; Humans; Isoniazid; Male; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 2005 |
Inhalable alginate nanoparticles as antitubercular drug carriers against experimental tuberculosis.
Topics: Aerosols; Alginates; Animals; Antitubercular Agents; Drug Carriers; Drug Evaluation, Preclinical; Female; Glucuronic Acid; Guinea Pigs; Hexuronic Acids; Inhalation; Isoniazid; Liver; Lung; Male; Mycobacterium tuberculosis; Nanostructures; Pyrazinamide; Rifampin; Spleen; Time Factors; Tuberculosis | 2005 |
[Two pregnant immigrant women with tuberculous peritonitis].
Topics: Adult; Antitubercular Agents; Diagnosis, Differential; Drug Therapy, Combination; Ethambutol; Female; Fetal Death; Humans; Isoniazid; Peritonitis, Tuberculous; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Pyrazinamide; Rifampin | 2005 |
[Tuberculoma complicating tuberculous meningitis: description of one paediatric case].
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents; Antibiotics, Antitubercular; Antitubercular Agents; Child; Drug Therapy, Combination; Ethambutol; Female; Follow-Up Studies; Humans; Isoniazid; Magnetic Resonance Imaging; Prednisone; Pyrazinamide; Rifampin; Streptomycin; Time Factors; Tomography, X-Ray Computed; Treatment Outcome; Tuberculoma, Intracranial; Tuberculosis, Meningeal | 2005 |
Simple means to alleviate sensitivity loss by trifluoroacetic acid (TFA) mobile phases in the hydrophilic interaction chromatography-electrospray tandem mass spectrometric (HILIC-ESI/MS/MS) bioanalysis of basic compounds.
Topics: Acetic Acid; Chromatography, Liquid; Cotinine; Ethionamide; Fluconazole; Humans; Isoniazid; Nicotine; Piperazines; Propionates; Purines; Pyrazinamide; Sensitivity and Specificity; Sildenafil Citrate; Spectrometry, Mass, Electrospray Ionization; Sulfones; Trifluoroacetic Acid | 2005 |
Tuberculous meningitis in BCG vaccinated and unvaccinated children.
Topics: Antitubercular Agents; BCG Vaccine; Child, Preschool; Female; Humans; Injections, Intramuscular; Isoniazid; Male; Pyrazinamide; Rifampin; Tuberculosis, Meningeal; Vaccination | 2005 |
Concurrence of granular cell tumor and Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Bronchoscopy; Ethambutol; Granular Cell Tumor; Humans; Isoniazid; Lung; Male; Middle Aged; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis | 2005 |
[Cervical spondylodiscitis: one pathogen may hide another].
Topics: Anti-Bacterial Agents; Antitubercular Agents; Aza Compounds; Cervical Vertebrae; Cholecystitis; Discitis; Disease Progression; Drug Therapy, Combination; Escherichia coli; Escherichia coli Infections; Ethambutol; Fluoroquinolones; France; Humans; Immobilization; Isoniazid; Male; Middle Aged; Morocco; Moxifloxacin; Mycobacterium tuberculosis; Pyrazinamide; Quinolines; Radiography; Rifampin; Tuberculosis, Spinal | 2006 |
Usefulness of E-test strips for testing susceptibility of Mycobacterium tuberculosis complex strains.
Topics: Antitubercular Agents; Drug Resistance, Bacterial; Ethambutol; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrazinamide; Reagent Strips; Rifampin; Streptomycin | 2005 |
Reactivation of tuberculosis after apparently adequate chemoprophylaxis.
Topics: Adolescent; Antitubercular Agents; Chemoprevention; Contact Tracing; Disease Transmission, Infectious; Ethambutol; Female; Humans; Isoniazid; Molecular Diagnostic Techniques; Mycobacterium tuberculosis; Pyrazinamide; Recurrence; Rifampin; Tuberculosis, Pulmonary | 2005 |
A 2-year-old girl with an abnormal gait.
Topics: Antitubercular Agents; Child, Preschool; Diagnosis, Differential; Drug Therapy, Combination; Ethambutol; Female; Gait Ataxia; Humans; Isoniazid; Osteomyelitis; Physical Examination; Pyrazinamide; Rifampin; Tuberculosis, Spinal | 2005 |
Drug-drug interaction studies on first-line anti-tuberculosis drugs.
Topics: Antitubercular Agents; Chromatography, Liquid; Drug Combinations; Drug Compounding; Drug Incompatibility; Drug Stability; Drug Storage; Ethambutol; Hot Temperature; Humidity; Isoniazid; Mass Spectrometry; Pyrazinamide; Rifampin | 2005 |
Artificial neural networks to optimize formulation components of a fixed-dose combination of rifampicin, isoniazid and pyrazinamide in a microemulsion.
Topics: Antibiotics, Antitubercular; Antitubercular Agents; Caprylates; Chemistry, Pharmaceutical; Child; Drug Combinations; Drug Stability; Emulsions; Humans; Isoniazid; Neural Networks, Computer; Polyethylene Glycols; Polysorbates; Pyrazinamide; Rifampin; Solubility; Sorbitol; Triglycerides | 2005 |
Adverse drug reactions observed during DOTS.
Topics: Adolescent; Adult; Antitubercular Agents; Directly Observed Therapy; Drug Administration Schedule; Drug Therapy, Combination; Ethambutol; Female; Humans; India; Isoniazid; Male; Middle Aged; National Health Programs; Patient Compliance; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis | 2004 |
[Efficiency of preventive chemotherapy in children and adolescents from the bacterial isolation foci of tuberculous infection].
Topics: Adolescent; Anti-Bacterial Agents; Antitubercular Agents; Child; Drug Resistance, Bacterial; Female; Humans; Isoniazid; Male; Pyrazinamide; Streptomycin; Tuberculosis | 2006 |
Determinants of rifampin, isoniazid, pyrazinamide, and ethambutol pharmacokinetics in a cohort of tuberculosis patients.
Topics: Adult; Antitubercular Agents; Area Under Curve; Cohort Studies; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Multivariate Analysis; Prospective Studies; Pyrazinamide; Rifampin; Tuberculosis | 2006 |
Potent twice-weekly rifapentine-containing regimens in murine tuberculosis.
Topics: Animals; Antitubercular Agents; Aza Compounds; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluoroquinolones; Isoniazid; Mice; Mice, Inbred BALB C; Moxifloxacin; Pyrazinamide; Quinolines; Rifampin; Tuberculosis, Pulmonary | 2006 |
Pharmacokinetic and pharmacodynamic behaviour of antitubercular drugs encapsulated in alginate nanoparticles at two doses.
Topics: Alginates; Animals; Antitubercular Agents; Area Under Curve; Chemistry, Pharmaceutical; Dose-Response Relationship, Drug; Ethambutol; Female; Glucuronic Acid; Hexuronic Acids; Isoniazid; Male; Mice; Nanostructures; Pyrazinamide; Rifampin; Tissue Distribution | 2006 |
Terminalia chebula (fruit) prevents liver toxicity caused by sub-chronic administration of rifampicin, isoniazid and pyrazinamide in combination.
Topics: Animals; Antibiotics, Antitubercular; Antitubercular Agents; Cell Survival; Cells, Cultured; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Drug Combinations; Fruit; Hepatocytes; Isoniazid; Lipid Peroxidation; Oxidative Stress; Pyrazinamide; Rats; Rifampin; Terminalia | 2006 |
Multidrug-resistant tuberculosis in military recruits.
Topics: Adult; Antitubercular Agents; Drug Resistance, Multiple, Bacterial; Female; Humans; Isoniazid; Military Personnel; Pyrazinamide; Radiography, Thoracic; Rifampin; Tuberculin Test; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; United States | 2006 |
[Tuberculosis of the submandibular gland: a case report].
Topics: Antitubercular Agents; Combined Modality Therapy; Diagnosis, Differential; Ethambutol; Female; Humans; Isoniazid; Middle Aged; Pyrazinamide; Rifampin; Submandibular Gland Diseases; Tuberculosis, Oral | 2006 |
A boy undergoing maintenance hemodialysis who developed mediastinal lymph node tuberculosis.
Topics: Child; Drug Therapy, Combination; Glomerulosclerosis, Focal Segmental; Humans; Isoniazid; Lymph Nodes; Male; Mediastinum; Mycobacterium tuberculosis; Pyrazinamide; Renal Dialysis; Rifampin; Tuberculosis, Lymph Node | 2006 |
The use of real-time polymerase chain reaction for rapid diagnosis of skeletal tuberculosis.
Topics: Antitubercular Agents; Bacterial Typing Techniques; DNA, Bacterial; Drug Therapy, Combination; Ethambutol; Female; Femur; Humans; Isoniazid; Middle Aged; Mycobacterium tuberculosis; Osteolysis; Pyrazinamide; Reverse Transcriptase Polymerase Chain Reaction; Rifampin; Tuberculosis, Osteoarticular | 2006 |
Combination chemotherapy with the nitroimidazopyran PA-824 and first-line drugs in a murine model of tuberculosis.
Topics: Animals; Antibiotics, Antitubercular; Antitubercular Agents; Disease Models, Animal; Drug Therapy, Combination; Ethambutol; Female; Isoniazid; Mice; Mice, Inbred BALB C; Mycobacterium tuberculosis; Nitroimidazoles; Pyrazinamide; Rifampin; Secondary Prevention; Time Factors; Tuberculosis, Pulmonary | 2006 |
Impact of country of origin on drug-resistant tuberculosis among foreign-born persons in British Columbia.
Topics: Adolescent; Adult; Age Factors; Aged; Analysis of Variance; Anti-Bacterial Agents; Antibiotics, Antitubercular; British Columbia; Child; Child, Preschool; Drug Resistance, Multiple, Bacterial; Emigration and Immigration; Ethambutol; Female; Humans; Infant; Infant, Newborn; Isoniazid; Logistic Models; Male; Microbial Sensitivity Tests; Middle Aged; Mycobacterium tuberculosis; Odds Ratio; Pyrazinamide; Rifampin; Risk Factors; Streptomycin; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 2006 |
Impact of DOTS expansion on tuberculosis related outcomes and costs in Haiti.
Topics: Antitubercular Agents; Cost of Illness; Directly Observed Therapy; Drug Therapy, Combination; Ethambutol; Haiti; Health Care Costs; Humans; Isoniazid; Program Evaluation; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Pulmonary; World Health Organization | 2006 |
Ocular tuberculosis in acquired immunodeficiency syndrome.
Topics: Abscess; Adolescent; Adult; AIDS-Related Opportunistic Infections; Antitubercular Agents; CD4 Lymphocyte Count; Child; Conjunctival Diseases; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Panophthalmitis; Pyrazinamide; Retinal Diseases; Retrospective Studies; Rifampin; Tuberculosis, Central Nervous System; Tuberculosis, Ocular; Tuberculosis, Pulmonary | 2006 |
Use of nonlinear mixed-effects analysis for improved precision of early pharmacodynamic measures in tuberculosis treatment.
Topics: Antitubercular Agents; Humans; Isoniazid; Models, Biological; Nonlinear Dynamics; Pyrazinamide; Rifampin; Sputum; Streptomycin; Thioacetazone; Tuberculosis, Pulmonary | 2006 |
[Addisonian crises induced by rifampicin].
Topics: Addison Disease; Aged; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Female; Humans; Isoniazid; Pyrazinamide; Rifampin; Tuberculosis, Miliary | 2006 |
Penile tuberculosis associated with monoclonal gammopathy of undetermined significance.
Topics: Aged; Antitubercular Agents; Ethambutol; Humans; Isoniazid; Male; Mycobacterium tuberculosis; Paraproteinemias; Penile Diseases; Pyrazinamide; Rifampin; Tuberculosis, Cutaneous; Tuberculosis, Male Genital | 2006 |
Co-existence of spontaneous splenic rupture and tuberculosis of the spleen.
Topics: Aged; Antitubercular Agents; Drug Therapy, Combination; Humans; Isoniazid; Lactones; Male; Pyrazinamide; Rupture, Spontaneous; Splenic Rupture; Sulfones; Tuberculosis, Splenic | 2006 |
Dissolution testing of marketed rifampicin containing fixed dose combination formulations using a new discriminative media: a post marketing retrospective study.
Topics: Antitubercular Agents; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Drug Combinations; Isoniazid; Kinetics; Pyrazinamide; Reference Standards; Retrospective Studies; Rifampin; Solubility; Spectrophotometry, Ultraviolet | 2006 |
Tuberculid of the glans penis.
Topics: Adult; Antibiotics, Antitubercular; Drug Therapy, Combination; Humans; Isoniazid; Male; Middle Aged; Penile Diseases; Pyrazinamide; Rifampin; Tuberculosis, Cutaneous | 2006 |
Sir, I turned much darker!
Topics: Addison Disease; Adult; Antitubercular Agents; Ethambutol; Germany; Humans; Hydrocortisone; Hyperpigmentation; Isoniazid; Male; Pyrazinamide; Rifampin; Tuberculosis, Endocrine | 2006 |
Mycobacterium tuberculosis presenting as chronic red eye.
Topics: Adolescent; Antitubercular Agents; Chronic Disease; Conjunctivitis, Bacterial; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Male; Pyrazinamide; Rifampin; Tuberculosis, Ocular | 2006 |
[Acquired ichthyosis revealing hepatic and lymph node tuberculosis].
Topics: Adult; Antibiotics, Antitubercular; Antitubercular Agents; Biopsy; Drug Therapy, Combination; Follow-Up Studies; Hepatitis C, Chronic; Humans; Ichthyosis; Isoniazid; Laparotomy; Liver; Lymph Nodes; Male; Pyrazinamide; Rifampin; Time Factors; Treatment Outcome; Tuberculosis, Hepatic; Tuberculosis, Lymph Node | 2006 |
Absence of an association between Mycobacterium tuberculosis genotype and clinical features in children with tuberculous meningitis.
Topics: Adolescent; Antibiotics, Antitubercular; Antitubercular Agents; Child; Child, Preschool; Ethionamide; Female; Genotype; Humans; Infant; Isoniazid; Male; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrazinamide; Retrospective Studies; Rifampin; Treatment Outcome; Tuberculosis, Meningeal | 2007 |
Moxifloxacin-induced arthropathy.
Topics: Aged, 80 and over; Antitubercular Agents; Arthritis; Aza Compounds; Drug Therapy, Combination; Fluoroquinolones; Humans; Isoniazid; Male; Moxifloxacin; Pyrazinamide; Quinolines; Rifampin; Tuberculosis, Pulmonary | 2007 |
PCR identification of Mycobacterium tuberculosis complex in a clinical sample from a patient with symptoms of tuberculous spondylodiscitis.
Topics: Adult; Antitubercular Agents; Biopsy; Discitis; Drug Therapy, Combination; Humans; Isoniazid; Male; Mycobacterium tuberculosis; Polymerase Chain Reaction; Pyrazinamide; Rifampin; Thoracic Vertebrae; Tuberculin Test; Tuberculosis, Spinal | 2007 |
Optimization of a stability-indicating HPLC method for the simultaneous determination of rifampicin, isoniazid, and pyrazinamide in a fixed-dose combination using artificial neural networks.
Topics: Biological Availability; Chromatography, High Pressure Liquid; Drug Combinations; Hydrogen-Ion Concentration; Isoniazid; Neural Networks, Computer; Pyrazinamide; Reproducibility of Results; Rifampin; Sensitivity and Specificity | 2007 |
CHIH-DFT determination of the molecular structure infrared spectra, UV spectra and chemical reactivity of three antitubercular compounds: Rifampicin, Isoniazid and Pyrazinamide.
Topics: Antitubercular Agents; Isoniazid; Pyrazinamide; Rifampin; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet | 2007 |
Modification to improve efficiency of sampling schedules for BA/BE testing of FDC anti-tuberculosis drugs.
Topics: Antitubercular Agents; Area Under Curve; Biological Availability; Blood Specimen Collection; Ethambutol; Humans; Isoniazid; Pyrazinamide; Quality Assurance, Health Care; Rifampin; South Africa; Therapeutic Equivalency | 2007 |
Moxifloxacin and gatifloxacin in an acid model of persistent Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Aza Compounds; Colony Count, Microbial; Drug Synergism; Fluoroquinolones; Gatifloxacin; Hydrogen-Ion Concentration; Isoniazid; Moxifloxacin; Mycobacterium tuberculosis; Pyrazinamide; Quinolines; Rifampin; Time Factors | 2006 |
[A case of tuberculosis showing immune reconstitution syndrome after the initiation of antiretroviral therapy for HIV infection].
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Antitubercular Agents; Drug Therapy, Combination; Ethambutol; HIV-1; Humans; Isoniazid; Male; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary; Zidovudine | 2007 |
[Isoniazid-induced acute pancreatitis].
Topics: Acute Disease; Aged, 80 and over; Antitubercular Agents; Drug Therapy, Combination; Female; Femoral Neck Fractures; Fractures, Spontaneous; Humans; Isoniazid; Pancreatitis; Pyrazinamide; Rifampin; Tuberculosis, Osteoarticular | 2007 |
[Aseptic cerebral venous thrombosis and multiple cerebral tuberculomas associated with pulmonary miliary tuberculosis].
Topics: Acenocoumarol; Aged; Anticoagulants; Antitubercular Agents; Confusion; Drug Therapy, Combination; Female; Heparin; Humans; Immunocompromised Host; Isoniazid; Lateral Sinus Thrombosis; Pyrazinamide; Radiography; Rifampin; Streptomycin; Thrombophilia; Tuberculoma, Intracranial; Tuberculosis, Miliary; Tuberculosis, Pulmonary | 2007 |
Tuberculous uveitis after treatment with etanercept.
Topics: Antirheumatic Agents; Antitubercular Agents; Aqueous Humor; Arthritis, Rheumatoid; Drug Therapy, Combination; Etanercept; Female; Granuloma; Humans; Immunoglobulin G; Isoniazid; Middle Aged; Mycobacterium tuberculosis; Panuveitis; Pyrazinamide; Receptors, Tumor Necrosis Factor; Retrospective Studies; Rifampin; Tuberculosis, Ocular | 2007 |
[Case report: tuberculosis of parotid gland].
Topics: Adult; Antitubercular Agents; Biopsy; Diagnosis, Differential; Ethambutol; Humans; Isoniazid; Lymph Node Excision; Male; Parotid Diseases; Parotid Gland; Pyrazinamide; Radiography; Rifampin; Tuberculosis | 2007 |
Trend of anti-tuberculosis drug resistance in Korea, 1994-2004.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Child; Ethambutol; Humans; Isoniazid; Korea; Middle Aged; Prevalence; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 2007 |
[Case of liver tuberculosis requiring differentiation from liver metastasis of cancer].
Topics: Aged; Antitubercular Agents; Diagnosis, Differential; Ethambutol; Female; Humans; Isoniazid; Liver Neoplasms; Lymphatic Metastasis; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Hepatic; Tuberculosis, Lymph Node | 2007 |
[Centrofacial granulomatous inflammation].
Topics: Aged; Aged, 80 and over; Antibiotics, Antitubercular; Antitubercular Agents; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Lupus Vulgaris; Male; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Skin; Time Factors; Treatment Outcome; Tuberculin Test | 2007 |
Short-course regimens for latent tuberculosis: what is ready for prime time?
Topics: Antitubercular Agents; Humans; Isoniazid; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Tuberculosis; Virus Latency | 2007 |
Location of persisting mycobacteria in a Guinea pig model of tuberculosis revealed by r207910.
Topics: Animals; Antibiotics, Antitubercular; Antitubercular Agents; Colony Count, Microbial; Diarylquinolines; Female; Granuloma; Guinea Pigs; Hypoxia; Isoniazid; Lung; Mycobacterium tuberculosis; Nitroimidazoles; Pyrazinamide; Quinolines; Radiation-Sensitizing Agents; Rifampin; Spleen; Tuberculosis | 2007 |
The effect of pyrazinamide and rifampicin on isoniazid metabolism in rats.
Topics: Animals; Antibiotics, Antitubercular; Antitubercular Agents; Area Under Curve; Biological Availability; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Hydrazines; Intubation, Gastrointestinal; Isoniazid; Male; Pyrazinamide; Rats; Rats, Wistar; Rifampin; Time Factors | 2007 |
Effects of four Indian medicinal herbs on Isoniazid-, Rifampicin- and Pyrazinamide-induced hepatic injury and immunosuppression in guinea pigs.
Topics: Animals; Guinea Pigs; Immune Tolerance; India; Isoniazid; Liver; Neutrophils; Plants, Medicinal; Pyrazinamide; Rifampin | 2007 |
Tuberculous sacro-ileitis: two cases and radiological findings.
Topics: Abscess; Adult; Antitubercular Agents; Arthritis, Infectious; Brucellosis; Diagnosis, Differential; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Pyrazinamide; Radiography; Rifampin; Sacroiliac Joint; Tuberculosis, Osteoarticular; Tuberculosis, Pulmonary; Ultrasonography | 2007 |
Activity of ketoconazole against Mycobacterium tuberculosis in vitro and in the mouse model.
Topics: Administration, Oral; Animals; Antibiotics, Antitubercular; Antitubercular Agents; Drug Evaluation, Preclinical; Drug Synergism; Drug Therapy, Combination; Female; Isoniazid; Ketoconazole; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Time Factors; Treatment Outcome; Tuberculosis, Pulmonary | 2007 |
Adverse drug reactions associated with first-line anti-tuberculosis drug regimens.
Topics: Antitubercular Agents; Drug-Related Side Effects and Adverse Reactions; Humans; Isoniazid; Pyrazinamide; Rifampin; Tuberculosis | 2007 |
Successful treatment with intravenous immunoglobulins in a patient affected by dermatomyositis/systemic lupus erythematosus overlap syndrome and tuberculosis.
Topics: Antitubercular Agents; Dermatomyositis; Female; Humans; Immunoglobulins, Intravenous; Immunologic Factors; Isoniazid; Lupus Erythematosus, Systemic; Middle Aged; Pyrazinamide; Rifampin; Tuberculosis | 2007 |
The effect of rifampicin and pyrazinamide on isoniazid pharmacokinetics in rats.
Topics: Animals; Antibiotics, Antitubercular; Antitubercular Agents; Area Under Curve; Chromatography, High Pressure Liquid; Drug Interactions; Half-Life; Isoniazid; Male; Pyrazinamide; Rats; Rats, Wistar; Rifampin | 2007 |
[Loculated ascitis by peritoneal tuberculosis].
Topics: Antibiotics, Antitubercular; Antitubercular Agents; Ascites; Drug Therapy, Combination; Follow-Up Studies; Humans; Isoniazid; Male; Middle Aged; Peritonitis, Tuberculous; Pyrazinamide; Radiography, Abdominal; Rifampin; Time Factors; Tomography, X-Ray Computed; Treatment Outcome | 2007 |
[Principles in the performance of chemotherapy in dispensary group VI children and adolescents].
Topics: Adolescent; Antitubercular Agents; Child; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Follow-Up Studies; Humans; Isoniazid; Outpatients; Pyrazinamide; Retrospective Studies; Treatment Outcome; Tuberculin Test; Tuberculosis, Pulmonary | 2007 |
[Ascites by peritoneal tuberculosis].
Topics: Antibiotics, Antitubercular; Antitubercular Agents; Ascites; Drug Therapy, Combination; Follow-Up Studies; Humans; Isoniazid; Male; Middle Aged; Peritonitis, Tuberculous; Pyrazinamide; Radiography, Abdominal; Rifampin; Time Factors; Tomography, X-Ray Computed | 2007 |
Elevated gatifloxacin and reduced rifampicin concentrations in a single-dose interaction study amongst healthy volunteers.
Topics: Aged; Antibiotics, Antitubercular; Area Under Curve; Cross-Over Studies; Drug Interactions; Female; Fluoroquinolones; Gatifloxacin; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin | 2007 |
[Case of fatal liver failure due to anti-tuberculous therapy].
Topics: Aged; Antitubercular Agents; Drug Therapy, Combination; Ethambutol; Fatal Outcome; Female; Humans; Isoniazid; Liver Failure; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 2007 |
Failure of chemoprophylaxis with standard antituberculosis agents in child contacts of multidrug-resistant tuberculosis cases.
Topics: Adolescent; Antibiotic Prophylaxis; Antitubercular Agents; Contact Tracing; Female; Humans; Infant; Isoniazid; Male; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Treatment Failure; Tuberculosis, Multidrug-Resistant | 2007 |
[Mycobacterium ulcerans infection treated by Rifater, pyrazynamide, Myambutol, and surgery: a case report with a 6-year follow-up].
Topics: Anti-Bacterial Agents; Buruli Ulcer; Child; Chloramines; Combined Modality Therapy; Drug Combinations; Drug Therapy, Combination; Ethambutol; Female; Follow-Up Studies; Humans; Isoniazid; Mastectomy; Metronidazole; Mycobacterium ulcerans; Nitrofurantoin; Pleurisy; Prednisolone; Pyrazinamide; Recurrence; Rifampin; Skin Transplantation | 2008 |
Daily dosing of rifapentine cures tuberculosis in three months or less in the murine model.
Topics: Animals; Antibiotics, Antitubercular; Antitubercular Agents; Aza Compounds; Colony Count, Microbial; Disease Models, Animal; Drug Administration Schedule; Drug Therapy, Combination; Fluoroquinolones; Isoniazid; Lung; Mice; Mice, Inbred BALB C; Moxifloxacin; Mycobacterium tuberculosis; Pyrazinamide; Quinolines; Rifampin; Secondary Prevention; Time Factors; Tuberculosis | 2007 |
Pattern of adverse drug reactions experienced by tuberculosis patients in a tertiary care teaching hospital in Western Nepal.
Topics: Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Antitubercular Agents; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Directly Observed Therapy; Female; Hospitals, Teaching; Humans; Isoniazid; Liver Function Tests; Male; Middle Aged; Nepal; Polypharmacy; Pyrazinamide; Retrospective Studies; Severity of Illness Index; Tuberculosis, Pulmonary | 2008 |
[A surgically treated case of ileus caused by small intestinal tuberculosis during treatment for pulmonary tuberculosis].
Topics: Adult; Antitubercular Agents; Ethambutol; Humans; Ileal Diseases; Ileus; Isoniazid; Male; Pyrazinamide; Rifampin; Tuberculosis, Gastrointestinal; Tuberculosis, Pulmonary | 2007 |
Treatment of isoniazid-resistant pulmonary tuberculosis.
Topics: Adult; Aged; Antitubercular Agents; Drug Administration Schedule; Drug Resistance, Microbial; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Medical Audit; Microbial Sensitivity Tests; Middle Aged; Mycobacterium tuberculosis; Pyrazinamide; Retrospective Studies; Rifampin; Treatment Failure; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 2008 |
Cerebral vacuolation induced in rats by the administration of LUP-3FDC, an anti-tuberculosis cocktail.
Topics: Administration, Oral; Animals; Antitubercular Agents; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Fluoroquinolones; Gatifloxacin; Isoniazid; Male; Microscopy, Electron; Pyrazinamide; Rats; Rats, Wistar; Rifampin; Toxicity Tests, Chronic; Ultrasonography; Vacuoles | 2008 |
[Case of bladder tuberculosis with onset at the age of nineteen--treatment of urinary tract tuberculosis in accordance with the new Japanese Tuberculosis Treatment Guidelines].
Topics: Adult; Antitubercular Agents; Diagnostic Imaging; Drug Therapy, Combination; Follow-Up Studies; Humans; Isoniazid; Japan; Male; Practice Guidelines as Topic; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Urogenital; Urinary Bladder Diseases | 2008 |
[A case of development of acute miliary tuberculosis].
Topics: Acute Disease; Adult; Antitubercular Agents; Humans; Isoniazid; Male; Pyrazinamide; Radiography; Rifampin; Streptomycin; Treatment Outcome; Tuberculosis, Miliary | 2008 |
[Tuberculosis dactylis: a case report].
Topics: Antibiotics, Antitubercular; Antitubercular Agents; Biopsy; Child; Drug Therapy, Combination; Ethambutol; Female; Fingers; Humans; Isoniazid; Pyrazinamide; Radiography; Rifampin; Time Factors; Treatment Outcome; Tuberculin Test; Tuberculosis, Osteoarticular | 2008 |
Isoniazid and its toxic metabolite hydrazine induce in vitro pyrazinamide toxicity.
Topics: Antitubercular Agents; Cell Line, Tumor; Cell Survival; Chemical and Drug Induced Liver Injury; Humans; Hydrazines; Isoniazid; Liver; Pyrazinamide; Rifampin | 2008 |
Hepatotoxicity of pyrazinamide: cohort and case-control analyses.
Topics: Adult; Aged; Antitubercular Agents; Case-Control Studies; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Female; Humans; Isoniazid; Logistic Models; Male; Matched-Pair Analysis; Middle Aged; Multivariate Analysis; Pyrazinamide; Rifampin; Tuberculosis | 2008 |
Protective effect of Tinospora cordifolia, Phyllanthus emblica and their combination against antitubercular drugs induced hepatic damage: an experimental study.
Topics: Animals; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Isoniazid; Liver Cirrhosis; Liver Diseases; Male; Necrosis; Phyllanthus emblica; Phytotherapy; Plant Extracts; Pyrazinamide; Rats; Rats, Wistar; Rifampin; Tinospora | 2008 |
Influence of glutathione S-transferase M1 and T1 homozygous null mutations on the risk of antituberculosis drug-induced hepatotoxicity in a Caucasian population.
Topics: Adult; Alanine Transaminase; Antitubercular Agents; Aspartate Aminotransferases; Case-Control Studies; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Female; Genetic Predisposition to Disease; Glutathione Transferase; Homozygote; Humans; Isoniazid; Male; Middle Aged; Mutation; Polymorphism, Genetic; Prospective Studies; Pyrazinamide; Rifampin; White People | 2008 |
An unusual case of chylothorax complicating childhood tuberculosis.
Topics: Antitubercular Agents; Bronchoalveolar Lavage; Bronchoalveolar Lavage Fluid; Bronchoscopy; Chest Tubes; Chylothorax; Diagnosis, Differential; Drug Therapy, Combination; Gastrointestinal Agents; Humans; Infant; Isoniazid; Male; Mycobacterium tuberculosis; Octreotide; Pyrazinamide; Rifampin; Streptomycin; Tomography, X-Ray Computed; Tuberculin Test; Tuberculosis, Pulmonary | 2008 |
[Exposure to multiresisant tuberculosis: study and follow-up of nine children].
Topics: Adolescent; Antitubercular Agents; Child; Child, Preschool; Environmental Exposure; Female; Follow-Up Studies; Humans; Infant; Isoniazid; Male; Pyrazinamide; Rifampin; Tuberculosis, Multidrug-Resistant | 2008 |
Papulonecrotic tuberculids associated with uveitis.
Topics: Adult; Antitubercular Agents; Drug Therapy, Combination; Ethambutol; Glucocorticoids; Humans; Isoniazid; Male; Ophthalmic Solutions; Pyrazinamide; Rifampin; Tuberculin Test; Tuberculosis, Cutaneous; Tuberculosis, Ocular; Uveitis | 2008 |
Tuberculosis of transverse testicular ectopic testis associated with persistent mullerian duct syndrome.
Topics: Abnormalities, Multiple; Antitubercular Agents; Choristoma; Cryptorchidism; Drug Therapy, Combination; Hernia, Inguinal; Humans; Infant; Isoniazid; Male; Mullerian Ducts; Pyrazinamide; Rifampin; Syndrome; Testicular Diseases; Tuberculosis, Male Genital; Urologic Surgical Procedures, Male | 2008 |
Cycloserine-induced encephalopathy: evidence on brain MRI.
Topics: Aged; Antibiotics, Antitubercular; Brain Diseases; Cycloserine; Disorders of Excessive Somnolence; Drug Therapy, Combination; Dyskinesias; Female; Humans; Isoniazid; Magnetic Resonance Imaging; Pyrazinamide; Pyridoxine; Tuberculosis, Lymph Node | 2008 |
Psoriasiform lupus vulgaris.
Topics: Adolescent; Antitubercular Agents; Biopsy; Buttocks; Child; Disease Progression; Ethambutol; Female; Humans; Isoniazid; Lupus Vulgaris; Pyrazinamide; Pyridoxine; Rifampin; Tuberculin Test; Vitamin B Complex | 2008 |
Primary drug resistance against Mycobacterium tuberculosis in Karachi.
Topics: Adolescent; Adult; Antitubercular Agents; Bronchoscopy; Drug Resistance, Multiple, Bacterial; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Mycobacterium tuberculosis; Pakistan; Pilot Projects; Pyrazinamide; Sputum; Streptomycin; Tuberculosis, Pulmonary | 2008 |
Diagnostic challenges of intestinal tuberculosis in a patient with chronic diarrhoea: case report.
Topics: Adult; Antitubercular Agents; Chronic Disease; Diarrhea; Ethambutol; Humans; Isoniazid; Laparotomy; Male; Pyrazinamide; Rifampin; Tuberculosis, Gastrointestinal | 2008 |
One to make the diagnosis. A case of non tuberculous mycobacterial mastoiditis in a nine year old female.
Topics: Antibiotics, Antitubercular; Antitubercular Agents; Child; Ethambutol; Female; Humans; Ireland; Isoniazid; Mastoiditis; Nontuberculous Mycobacteria; Pyrazinamide; Rifampin | 2008 |
Drug lymphocyte stimulation test in the diagnosis of adverse reactions to antituberculosis drugs.
Topics: Adult; Aged; Aged, 80 and over; Antitubercular Agents; Ethambutol; Female; Follow-Up Studies; Humans; Isoniazid; Lymphocyte Activation; Male; Middle Aged; Prospective Studies; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis | 2008 |
Genitourinary tuberculosis in pediatric urological practice.
Topics: Antibiotics, Antitubercular; Child; Drug Therapy, Combination; Education, Medical, Continuing; Female; Follow-Up Studies; Humans; Isoniazid; Male; Pediatrics; Pyrazinamide; Retrospective Studies; Rifampin; Tuberculosis, Urogenital; Urology | 2008 |
Impact of the interaction of R207910 with rifampin on the treatment of tuberculosis studied in the mouse model.
Topics: Animals; Antibiotics, Antitubercular; Antitubercular Agents; Colony Count, Microbial; Diarylquinolines; Disease Models, Animal; Drug Interactions; Female; Humans; Isoniazid; Lung; Mice; Mycobacterium tuberculosis; Pyrazinamide; Quinolines; Rifampin; Spleen; Tuberculosis, Pulmonary | 2008 |
Enhanced bactericidal activity of rifampin and/or pyrazinamide when combined with PA-824 in a murine model of tuberculosis.
Topics: Animals; Antibiotics, Antitubercular; Antitubercular Agents; Colony Count, Microbial; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Female; Isoniazid; Lung; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Nitroimidazoles; Pyrazinamide; Recurrence; Rifampin; Tuberculosis, Pulmonary | 2008 |
Gynaecomastia during antituberculosis chemotherapy with isoniazid.
Topics: Adult; Antitubercular Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Gynecomastia; Humans; India; Isoniazid; Male; Pyrazinamide; Rifampin; Tuberculosis, Lymph Node | 2008 |
Hoarseness due to Mycobacterium kansasii.
Topics: Antitubercular Agents; Drug Combinations; Hoarseness; Humans; Isoniazid; Male; Middle Aged; Mycobacterium Infections, Nontuberculous; Mycobacterium kansasii; Pyrazinamide; Rifampin; Sputum; Treatment Outcome; Vocal Cord Paralysis | 2009 |
Isoniazid or moxifloxacin in rifapentine-based regimens for experimental tuberculosis?
Topics: Animals; Antibiotics, Antitubercular; Antitubercular Agents; Aza Compounds; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluoroquinolones; Isoniazid; Lung; Mice; Mice, Inbred BALB C; Moxifloxacin; Pyrazinamide; Quinolines; Recurrence; Rifampin; Time Factors; Treatment Outcome; Tuberculosis | 2008 |
Update on the treatment of tuberculosis.
Topics: Antitubercular Agents; Comorbidity; Directly Observed Therapy; Disease Progression; Drug Therapy, Combination; Ethambutol; Female; HIV Infections; Humans; Isoniazid; Male; Mass Screening; Mycobacterium tuberculosis; Patient Compliance; Pregnancy; Pregnancy Complications, Infectious; Pyrazinamide; Rifampin; Risk Factors; Tuberculin Test; Tuberculosis | 2008 |
Measurement of the concentration of three antituberculosis drugs in the focus of spinal tuberculosis.
Topics: Adult; Antitubercular Agents; Biopsy; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Sclerosis; Spine; Tomography, X-Ray Computed; Tuberculosis, Spinal; Young Adult | 2008 |
Scapholunate dissociation: a rare presentation of TB wrist in a case of multi-focal skeletal tuberculosis.
Topics: Adolescent; Antitubercular Agents; Arthritis, Infectious; Arthrodesis; Carpal Joints; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Lunate Bone; Pyrazinamide; Radiography; Range of Motion, Articular; Rifampin; Scaphoid Bone; Tuberculosis, Osteoarticular | 2008 |
An unusual case of a pleural effusion with an abdominal mass.
Topics: Adult; Antitubercular Agents; Drainage; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Male; Pleural Effusion; Pyrazinamide; Rifampin; Tomography, X-Ray Computed; Tuberculosis, Pulmonary; Tuberculosis, Renal | 2008 |
[Sternal tuberculosis].
Topics: Antitubercular Agents; Biopsy, Fine-Needle; Debridement; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Middle Aged; Pyrazinamide; Rifampin; Sternum; Tuberculosis, Osteoarticular | 2008 |
Prostatic tuberculosis: case report.
Topics: Adult; Antitubercular Agents; Humans; Immunocompetence; Isoniazid; Male; Mycobacterium tuberculosis; Prostatic Diseases; Pyrazinamide; Rifampin; Tomography, X-Ray Computed; Tuberculosis, Male Genital | 2008 |
Postoperative Mycobacterium tuberculosis infection after total knee arthroplasty.
Topics: Aged; Antitubercular Agents; Arthroplasty, Replacement, Knee; Drug Combinations; Ethambutol; Female; Humans; Isoniazid; Pyrazinamide; Rifampin; Taiwan; Tuberculosis, Osteoarticular | 2009 |
Tuberculosis in a patient on temozolomide: a case report.
Topics: Anti-Infective Agents; Anti-Inflammatory Agents; Anti-Ulcer Agents; Antibiotics, Antitubercular; Anticholesteremic Agents; Anticonvulsants; Antineoplastic Agents, Alkylating; Atorvastatin; Brain Neoplasms; Combined Modality Therapy; Cyclosporine; Dacarbazine; Dexamethasone; Female; Fluoxetine; Glioblastoma; Heptanoic Acids; Humans; Immunosuppressive Agents; Isoniazid; Middle Aged; Omeprazole; Phenobarbital; Prednisone; Pyrazinamide; Pyrroles; Radiotherapy; Red-Cell Aplasia, Pure; Rifampin; Temozolomide; Trimethoprim, Sulfamethoxazole Drug Combination; Tuberculosis, Pulmonary | 2009 |
[Application of near infrared spectroscopy in rapid and simultaneous determination of essential components in five varieties of anti-tuberculosis tablets].
Topics: Algorithms; Antitubercular Agents; Isoniazid; Models, Chemical; Principal Component Analysis; Pyrazinamide; Rifampin; Spectroscopy, Near-Infrared; Tablets | 2008 |
Tuberculous peritonitis after treatment with adalimumab.
Topics: Adalimumab; Aged; Antibiotics, Antitubercular; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Rheumatoid; Female; Humans; Isoniazid; Mycobacterium tuberculosis; Opportunistic Infections; Peritonitis, Tuberculous; Pyrazinamide; Rifampin | 2008 |
A 13-month-old with persistent right knee swelling.
Topics: Antitubercular Agents; Arthritis, Infectious; Arthritis, Juvenile; Diagnosis, Differential; Drug Therapy, Combination; Edema; Humans; Infant; Isoniazid; Knee; Knee Joint; Male; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Synovial Fluid; Synovial Membrane; Tuberculosis, Osteoarticular | 2008 |
Persistent pyrexia post-liver transplantation: a unique case of pericardial tuberculosis.
Topics: Antitubercular Agents; Drug Therapy, Combination; Female; Fever; Glucocorticoids; Humans; Immunocompromised Host; Isoniazid; Liver Cirrhosis, Biliary; Liver Transplantation; Middle Aged; Mycobacterium tuberculosis; Pericardiocentesis; Pericarditis, Tuberculous; Prednisolone; Pyrazinamide; Rifampin; Treatment Outcome | 2008 |
Tuberculous liver abscess.
Topics: Antibiotics, Antitubercular; Antitubercular Agents; Ethambutol; Humans; Isoniazid; Liver Abscess; Male; Middle Aged; Pyrazinamide; Rifampin; Tuberculosis, Hepatic | 2008 |
Application of the cobaltabisdicarbollide anion to the development of ion selective PVC membrane electrodes for tuberculosis drug analysis.
Topics: Antitubercular Agents; Hydrogen-Ion Concentration; Ion-Selective Electrodes; Isoniazid; Membranes, Artificial; Molecular Structure; Organometallic Compounds; Polyvinyl Chloride; Pyrazinamide; Spectroscopy, Fourier Transform Infrared | 2008 |
Clinical characteristics and treatment outcomes of patients with isoniazid-monoresistant tuberculosis.
Topics: Antitubercular Agents; Drug Resistance, Bacterial; Female; Humans; Isoniazid; Male; Middle Aged; Mycobacterium tuberculosis; Pyrazinamide; San Francisco; Treatment Outcome; Tuberculosis | 2009 |
Gynecomastia: a rare adverse effect of isoniazid.
Topics: Adolescent; Antitubercular Agents; Diagnosis, Differential; Gynecomastia; Humans; Isoniazid; Male; Pyrazinamide; Recurrence; Rifampin; Treatment Outcome; Tuberculosis, Pulmonary | 2008 |
Tuberculosis incidence among contacts of active pulmonary tuberculosis.
Topics: Adolescent; Adult; Antitubercular Agents; Brazil; Carrier State; Cohort Studies; Disease Transmission, Infectious; Female; Humans; Incidence; Isoniazid; Male; Middle Aged; Practice Guidelines as Topic; Predictive Value of Tests; Pyrazinamide; Retrospective Studies; Rifampin; Risk; Tuberculin Test; Tuberculosis, Pulmonary; Young Adult | 2009 |
Tuberculous meningitis in HIV-infected and non-infected patients: comparison of cerebrospinal fluid findings.
Topics: Adult; Antitubercular Agents; Cerebrospinal Fluid; Cerebrospinal Fluid Proteins; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Ethambutol; Female; Glucose; HIV Infections; Hospital Mortality; Humans; Isoniazid; Leukocyte Count; Male; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrazinamide; Retrospective Studies; Treatment Outcome; Tuberculosis, Meningeal; Young Adult | 2009 |
Multifocal skeletal tuberculosis in children.
Topics: Antibiotics, Antitubercular; Antitubercular Agents; Child, Preschool; Humans; Isoniazid; Male; Mycobacterium tuberculosis; Protein Synthesis Inhibitors; Psoas Abscess; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Osteoarticular | 2009 |
[Ex juvantibus diagnosis in suspected skin tuberculosis].
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Diagnosis, Differential; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Time Factors; Tuberculosis, Cutaneous | 2008 |
[A role of the HLA-DRB1* genotype in the complex therapy of pulmonary tuberculosis].
Topics: Alleles; Antibiotics, Antitubercular; Antitubercular Agents; Disease Progression; Drug Resistance, Bacterial; Follow-Up Studies; Genotype; HLA-DR Antigens; HLA-DRB1 Chains; Humans; Isoniazid; Mycobacterium tuberculosis; Polymerase Chain Reaction; Polymorphism, Genetic; Prognosis; Pyrazinamide; Radiography; Rifabutin; Rifampin; Time Factors; Tuberculosis, Pulmonary | 2008 |
[Cerebellar soap bubble lesions and mediastinal lymph nodes].
Topics: Adult; Antitubercular Agents; Brain Abscess; Cerebellar Diseases; Combined Modality Therapy; Craniotomy; Ethambutol; Female; Humans; Isoniazid; Magnetic Resonance Imaging; Mediastinum; Pyrazinamide; Rifampin; Tuberculosis, Central Nervous System; Tuberculosis, Lymph Node | 2009 |
[Renal mass in an HIV-positive elderly patient].
Topics: Aged; AIDS-Related Opportunistic Infections; Antitubercular Agents; Combined Modality Therapy; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Nephrectomy; Ofloxacin; Pyrazinamide; Tomography, X-Ray Computed; Tuberculosis, Renal | 2009 |
[Acute respiratory distress syndrome: a manifestation of immune reconstitution in an HIV-negative patient with tuberculosis].
Topics: Adult; Antitubercular Agents; Drug Therapy, Combination; Female; HIV Seronegativity; Humans; Isoniazid; Leukocyte Count; Leukocytes; Prednisone; Pyrazinamide; Respiratory Distress Syndrome; Rifampin; Tuberculosis, Pulmonary | 2009 |
[Optimization of chemotherapy regimens in children with primary pulmonary tuberculosis].
Topics: Adolescent; Age Factors; Antibiotics, Antitubercular; Antitubercular Agents; Child; Child, Preschool; Cycloserine; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Prothionamide; Pyrazinamide; Radiography, Thoracic; Rifampin; Streptomycin; Time Factors; Tuberculosis, Lymph Node; Tuberculosis, Pulmonary | 2009 |
Influence of diabetes on liver injury induced by antitubercular drugs and on silymarin hepatoprotection in rats.
Topics: Animals; Antitubercular Agents; Bilirubin; Chemical and Drug Induced Liver Injury; Diabetes Mellitus, Experimental; Female; Isoniazid; Liver; Liver Diseases; Liver Function Tests; Male; Protective Agents; Pyrazinamide; Rats; Rats, Wistar; Rifampin; Silymarin; Streptozocin | 2008 |
Coccidioides immitis and Mycobacterium tuberculosis diagnosed by endoscopic ultrasound.
Topics: Adult; Antibiotics, Antitubercular; Antifungal Agents; Antitubercular Agents; Coccidioides; Coccidioidomycosis; Endosonography; Ethambutol; Follow-Up Studies; Humans; Isoniazid; Itraconazole; Lymph Nodes; Male; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Time Factors; Treatment Outcome; Tuberculosis, Pulmonary | 2009 |
[Cervical tuberculous lymphadenitis: the location of surgery].
Topics: Adult; Anti-Bacterial Agents; Antitubercular Agents; Combined Modality Therapy; Diagnosis, Differential; Drug Combinations; Female; Humans; Isoniazid; Male; Neck; Pyrazinamide; Retrospective Studies; Rifampin; Tuberculosis, Lymph Node | 2009 |
Presumed ocular tuberculosis in an immunocompetent eight-year-old boy.
Topics: Antibiotics, Antitubercular; Antitubercular Agents; Child; Granulomatous Disease, Chronic; Humans; Isoniazid; Male; Pyrazinamide; Rifampin; Tuberculosis, Ocular; Uveitis, Anterior | 2009 |
Isoniazid induced gynaecomastia: a case report.
Topics: Antitubercular Agents; Drug Therapy, Combination; Ethambutol; Gynecomastia; Humans; Isoniazid; Male; Mammography; Middle Aged; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 2009 |
[Fever and thin-walled cavitary lung lesions].
Topics: Adult; Antitubercular Agents; Drug Therapy, Combination; Ethambutol; Fever; Humans; Isoniazid; Male; Mycobacterium Infections, Nontuberculous; Mycobacterium kansasii; Pyrazinamide; Radiography; Rifampin; Sputum; Tuberculosis, Pulmonary | 2009 |
Isoniazid, rifampin, ethambutol, and pyrazinamide pharmacokinetics and treatment outcomes among a predominantly HIV-infected cohort of adults with tuberculosis from Botswana.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antitubercular Agents; Botswana; CD4 Lymphocyte Count; Ethambutol; Female; HIV Infections; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Serum; Treatment Outcome; Tuberculosis, Pulmonary; Young Adult | 2009 |
[Primary tuberculosis of the tongue].
Topics: Adult; Antitubercular Agents; Humans; Isoniazid; Male; Pyrazinamide; Rifampin; Tongue Diseases; Tuberculosis | 2009 |
A tumor-like manifestation of extrapulmonary tuberculosis in a hemodialysis patient.
Topics: Diabetic Nephropathies; Diagnosis, Differential; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Liver; Liver Neoplasms; Magnetic Resonance Imaging; Male; Middle Aged; Mycobacterium tuberculosis; Pyrazinamide; Renal Dialysis; Rifampin; Tomography, X-Ray Computed; Tuberculosis, Hepatic | 2009 |
In vitro synergistic effects of antituberculous drugs plus antifungals against Coccidioides posadasii.
Topics: Amphotericin B; Antifungal Agents; Antitubercular Agents; Caspofungin; Coccidioides; Coccidioidomycosis; Drug Synergism; Echinocandins; Ethambutol; Fluconazole; Humans; Isoniazid; Itraconazole; Ketoconazole; Lipopeptides; Microbial Sensitivity Tests; Pyrazinamide; Pyrimidines; Triazoles; Voriconazole | 2009 |
Diagnosis of tuberculous uveitis: clinical application of an interferon-gamma release assay.
Topics: Adult; Antitubercular Agents; Area Under Curve; Drug Therapy, Combination; Enzyme-Linked Immunosorbent Assay; False Positive Reactions; Female; Humans; Interferon-gamma; Isoniazid; Lung; Male; Middle Aged; Predictive Value of Tests; Pyrazinamide; Radiography; Reagent Kits, Diagnostic; Retrospective Studies; Rifampin; ROC Curve; Sensitivity and Specificity; Tuberculin Test; Tuberculosis, Ocular; Uveitis | 2009 |
Sterilizing activity of R207910 (TMC207)-containing regimens in the murine model of tuberculosis.
Topics: Animals; Antitubercular Agents; Diarylquinolines; Disease Models, Animal; Drug Therapy, Combination; Female; Hydrolases; Isoniazid; Mice; Mycobacterium tuberculosis; Pyrazinamide; Quinolines; Rifampin; Tuberculosis; Tuberculosis, Pulmonary; Tuberculosis, Splenic | 2009 |
Pulmonary tuberculosis presenting as fever without source in a pediatric patient with acute lymphoblastic leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Antitubercular Agents; Azithromycin; Child, Preschool; Combined Modality Therapy; Contact Tracing; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Drug Therapy, Combination; Ethambutol; Fever of Unknown Origin; Humans; Immunocompromised Host; Isoniazid; Lymphopenia; Male; Mycobacterium tuberculosis; Pneumonectomy; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary; Vincristine | 2009 |
Paradoxical effect of isoniazid on the activity of rifampin-pyrazinamide combination in a mouse model of tuberculosis.
Topics: Animals; Antitubercular Agents; Drug Resistance, Bacterial; Drug Therapy, Combination; Female; Isoniazid; Mice; Mice, Inbred BALB C; Mutation; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 2009 |
Renal and miliary tuberculosis in an internationally adopted infant.
Topics: Adoption; Antitubercular Agents; Developing Countries; Ethiopia; Humans; Infant; Isoniazid; Male; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Tuberculosis, Miliary; Tuberculosis, Renal; United States | 2009 |
British Infection Society guidelines for the diagnosis and treatment of tuberculosis of the central nervous system in adults and children.
Topics: Adenosine Deaminase; Adult; Antibiotics, Antitubercular; Antitubercular Agents; Cerebrospinal Fluid; Child; Ethambutol; Humans; Isoniazid; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Spinal Puncture; Tuberculin Test; Tuberculoma, Intracranial; Tuberculosis, Meningeal; Tuberculosis, Spinal | 2009 |
Factors influencing time to smear conversion in patients with smear-positive pulmonary tuberculosis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antitubercular Agents; Child; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Mycobacterium; Proportional Hazards Models; Pyrazinamide; Retrospective Studies; Rifampin; Sputum; Time Factors; Treatment Outcome; Tuberculosis, Pulmonary; Young Adult | 2009 |
Incomplete immunological recovery following anti-tuberculosis treatment in HIV-infected individuals with active tuberculosis.
Topics: Acquired Immunodeficiency Syndrome; Analysis of Variance; beta 2-Microglobulin; Biomarkers; CD4-Positive T-Lymphocytes; Cell Count; Enzyme-Linked Immunosorbent Assay; Ethambutol; Humans; India; Isoniazid; Neopterin; Pyrazinamide; Receptors, Tumor Necrosis Factor, Type I; Rifampin; Tuberculosis | 2009 |
Pharmacokinetic interaction of some antitubercular drugs with caraway: implications in the enhancement of drug bioavailability.
Topics: Animals; Antitubercular Agents; Area Under Curve; Biological Availability; Carum; Chromatography, High Pressure Liquid; Drug Interactions; Female; Intestinal Absorption; Intestinal Mucosa; Isoniazid; Jejunum; Male; Plant Extracts; Pyrazinamide; Rats; Rats, Wistar; Reference Standards; Rifampin; Seeds; Solvents | 2009 |
Experimental ocular tuberculosis in guinea pigs.
Topics: Aerosols; Animals; Antitubercular Agents; Disease Models, Animal; DNA, Bacterial; Guinea Pigs; Isoniazid; Lung; Mycobacterium tuberculosis; Polymerase Chain Reaction; Pyrazinamide; Rifampin; Spleen; Tuberculosis, Ocular; Tuberculosis, Pulmonary | 2009 |
[Relapse rate of tuberculosis treated with standard regimen of chemotherapy].
Topics: Adolescent; Aged; Aged, 80 and over; Child; Diabetes Complications; Drug Administration Schedule; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Recurrence; Retrospective Studies; Rifampin; Tuberculosis, Pulmonary | 2009 |
Entrapment of multiple anti-Tb drugs in microemulsion system: quantitative analysis, stability, and in vitro release studies.
Topics: Antitubercular Agents; Drug Stability; Emulsions; Excipients; Isoniazid; Magnetic Resonance Spectroscopy; Models, Molecular; Pyrazinamide; Rifampin; Solubility; Viscosity | 2010 |
[Macular tuberculoma and optic neuritis: rare association with tuberculosis meningoencephalitis].
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antitubercular Agents; Calcinosis; Confusion; Diplopia; Drug Therapy, Combination; Fever; Humans; Isoniazid; Magnetic Resonance Imaging; Male; Meningoencephalitis; Middle Aged; Optic Neuritis; Papilledema; Pyrazinamide; Rifampin; Spinal Puncture; Streptomycin; Tuberculoma; Tuberculosis, Meningeal; Ultrasonography | 2009 |
Non conversion of sputum smears in new smear positive pulmonary tuberculosis patients in Yaoundé, Cameroon.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibiotics, Antitubercular; Antitubercular Agents; Cameroon; Child; Confidence Intervals; Ethambutol; Female; Humans; Isoniazid; Logistic Models; Male; Middle Aged; Mycobacterium tuberculosis; Odds Ratio; Prospective Studies; Pyrazinamide; Rifampin; Sputum; Time Factors; Treatment Outcome; Tuberculosis, Pulmonary; Young Adult | 2009 |
New susceptibility breakpoints for first-line antituberculosis drugs based on antimicrobial pharmacokinetic/pharmacodynamic science and population pharmacokinetic variability.
Topics: Antitubercular Agents; Aza Compounds; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Ethambutol; Fluoroquinolones; Humans; In Vitro Techniques; Isoniazid; Microbial Sensitivity Tests; Models, Biological; Monte Carlo Method; Moxifloxacin; Mycobacterium tuberculosis; Pyrazinamide; Quinolines; Rifampin; Tuberculosis; Tuberculosis, Multidrug-Resistant | 2010 |
Tween-embedded microemulsions--physicochemical and spectroscopic analysis for antitubercular drugs.
Topics: Antitubercular Agents; Chemistry, Pharmaceutical; Isoniazid; Kinetics; Magnetic Resonance Spectroscopy; Oleic Acid; Particle Size; Polysorbates; Pyrazinamide; Rifampin; Solubility; Spectrum Analysis; Surface-Active Agents; Viscosity | 2010 |
Comparison of the 'Denver regimen' against acute tuberculosis in the mouse and guinea pig.
Topics: Animals; Antitubercular Agents; Disease Models, Animal; Female; Guinea Pigs; Isoniazid; Lung; Mice; Mice, Inbred BALB C; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis | 2010 |
Tuberculous uveitis.
Topics: Antitubercular Agents; Area Under Curve; Drug Therapy, Combination; Enzyme-Linked Immunosorbent Assay; False Positive Reactions; Humans; Interferon-gamma; Isoniazid; Lung; Predictive Value of Tests; Pyrazinamide; Radiography; Reagent Kits, Diagnostic; Rifampin; ROC Curve; Sensitivity and Specificity; Tuberculin Test; Tuberculosis, Ocular; Uveitis | 2010 |
Simultaneous scrofuloderma and intracranial tuberculomas: a rare presentation of systemic tuberculosis.
Topics: Antitubercular Agents; Aza Compounds; Brain; Diagnosis, Differential; Drug Therapy, Combination; Fluoroquinolones; Humans; Isoniazid; Lichenoid Eruptions; Male; Middle Aged; Moxifloxacin; Pyrazinamide; Quinolines; Rifampin; Treatment Outcome; Tuberculoma, Intracranial; Tuberculosis, Cutaneous | 2010 |
Evaluation of standard chemotherapy in the guinea pig model of tuberculosis.
Topics: Animals; Animals, Outbred Strains; Antitubercular Agents; Biomarkers; CD8-Positive T-Lymphocytes; Disease Models, Animal; Drug Therapy, Combination; Female; Flow Cytometry; Forkhead Transcription Factors; Guinea Pigs; Interleukin-10; Isoniazid; Leukocyte Common Antigens; Lung; Lymph Nodes; Magnetic Resonance Imaging; Pyrazinamide; Rifampin; Th1 Cells; Tuberculosis, Pulmonary | 2010 |
Intestinal barrier function and serum concentrations of rifampin, isoniazid and pyrazinamide in patients with pulmonary tuberculosis.
Topics: Adult; Antitubercular Agents; Case-Control Studies; Female; Humans; Intestinal Absorption; Isoniazid; Male; Pyrazinamide; Rifampin; Time Factors; Tuberculosis, Pulmonary | 2009 |
Antituberculosis therapy-induced acute liver failure: magnitude, profile, prognosis, and predictors of outcome.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antitubercular Agents; Female; Hepatitis E; Humans; India; Isoniazid; Liver Failure, Acute; Male; Middle Aged; Prognosis; Prospective Studies; Pyrazinamide; Rifampin; Treatment Outcome | 2010 |
Rapid diagnosis of tuberculous pericarditis by ELISPOT assay.
Topics: Aged, 80 and over; Antitubercular Agents; Drug Combinations; Enzyme-Linked Immunospot Assay; Humans; Isoniazid; Male; Mycobacterium tuberculosis; Pericardial Effusion; Pericarditis, Tuberculous; Pyrazinamide; Rifampin; T-Lymphocytes | 2010 |
Incision infection with Mycobacterium tuberculosis after total hip arthroplasty without any primary tuberculosis focus.
Topics: Arthroplasty, Replacement, Hip; Drug Therapy, Combination; Ethambutol; Female; Hip Dislocation, Congenital; Hip Prosthesis; Humans; Isoniazid; Middle Aged; Mycobacterium tuberculosis; Prosthesis-Related Infections; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis | 2011 |
Predicting outcomes and drug resistance with standardised treatment of active tuberculosis.
Topics: Cohort Studies; Communicable Disease Control; Drug Resistance, Bacterial; Global Health; HIV Infections; Humans; Isoniazid; Pyrazinamide; Recurrence; Rifampin; Treatment Outcome; Tuberculosis, Multidrug-Resistant | 2010 |
Dysuria: don't take it lightly.
Topics: Adult; Antitubercular Agents; Drug Therapy, Combination; Dysuria; Ethambutol; Female; Humans; Isoniazid; Pyrazinamide; Rifampin; Tuberculosis, Female Genital; Tuberculosis, Renal; Urine | 2011 |
NAT2 and CYP2E1 polymorphisms and susceptibility to first-line anti-tuberculosis drug-induced hepatitis.
Topics: Adult; Aged; Aged, 80 and over; Antitubercular Agents; Arylamine N-Acetyltransferase; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Female; Genetic Predisposition to Disease; Genotype; Humans; Isoniazid; Male; Middle Aged; Polymerase Chain Reaction; Polymorphism, Genetic; Prospective Studies; Pyrazinamide; Risk Factors; Severity of Illness Index; Young Adult | 2010 |
Nasolacrimal tuberculosis: case report highlighting the need for imaging in identifying and managing it effectively.
Topics: Adult; Antitubercular Agents; Drug Combinations; Drug Therapy, Combination; Endoscopy; Ethambutol; Female; Humans; Isoniazid; Lacrimal Apparatus Diseases; Nasolacrimal Duct; Pyrazinamide; Pyridoxine; Rifampin; Tomography, X-Ray Computed; Tuberculosis, Ocular | 2010 |
Tuberculous uveitis.
Topics: Antitubercular Agents; Drug Therapy, Combination; Enzyme-Linked Immunosorbent Assay; Humans; Interferon-gamma; Isoniazid; Lung; Predictive Value of Tests; Pyrazinamide; Radiography; Rifampin; ROC Curve; Sensitivity and Specificity; Tuberculin Test; Tuberculosis, Ocular; Uveitis | 2010 |
A survey of prescribing pattern for osteoarticular tuberculosis: orthopaedic surgeons' and infectious disease experts' perspective.
Topics: Antitubercular Agents; Congresses as Topic; Ethambutol; Humans; Infectious Disease Medicine; Isoniazid; Ofloxacin; Orthopedics; Practice Patterns, Physicians'; Pyrazinamide; Rifampin; Streptomycin; Surveys and Questionnaires; Tuberculosis, Osteoarticular | 2009 |
Role of 2-month sputum smears in predicting culture conversion in pulmonary tuberculosis.
Topics: Adult; Aged; Aged, 80 and over; Antitubercular Agents; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Mycobacterium tuberculosis; Pyrazinamide; Radiography; Rifampin; Sensitivity and Specificity; Sputum; Treatment Outcome; Tuberculosis, Pulmonary | 2011 |
Pott's disease with scrofuloderma and psoas abscess misdiagnosed and treated as hidradenitis suppurativa.
Topics: Adult; Antibiotics, Antitubercular; Antitubercular Agents; Diagnosis, Differential; Diagnostic Errors; Ethambutol; Hidradenitis Suppurativa; Humans; Isoniazid; Male; Mycobacterium tuberculosis; Psoas Abscess; Pyrazinamide; Rifampin; Tuberculosis, Cutaneous; Tuberculosis, Spinal | 2011 |
[Onset of neurological symptoms during tuberculosis treatment: description of two cases].
Topics: Adult; Aged, 80 and over; Antitubercular Agents; Aphasia; Child, Preschool; Drug Therapy, Combination; Dystonia; Ethambutol; Facial Pain; Female; Humans; Isoniazid; Magnetic Resonance Imaging; Male; Nigeria; Prednisone; Pyrazinamide; Reflex, Abnormal; Rifampin; Tremor; Tuberculoma; Tuberculosis, Meningeal; Tuberculosis, Miliary | 2010 |
[A 95 year old woman with bilateral nodular pulmonary pattern].
Topics: Aged, 80 and over; Antitubercular Agents; Drug Therapy, Combination; Dyspnea; Emergencies; Fatal Outcome; Female; Humans; Isoniazid; Pyrazinamide; Rifampin; Tomography, X-Ray Computed; Tuberculosis, Pulmonary | 2012 |
Impact of adverse drug reaction and predictivity of quality of life status in tuberculosis.
Topics: Antitubercular Agents; British Columbia; Ethambutol; Female; Humans; Isoniazid; Longitudinal Studies; Male; Middle Aged; Pyrazinamide; Quality of Life; Retrospective Studies; Rifampin; Sickness Impact Profile; Tuberculosis, Pulmonary | 2010 |
The best approach to reintroducing tuberculosis treatment after hepatotoxicity is still open to debate.
Topics: Antitubercular Agents; Chemical and Drug Induced Liver Injury; Humans; Isoniazid; Pyrazinamide; Rifampin; Tuberculosis | 2010 |
Posttreatment reactivation of tuberculosis in mice caused by Mycobacterium tuberculosis disrupted in mce1R.
Topics: Animals; Antitubercular Agents; Bacterial Proteins; Disease Models, Animal; Female; Humans; Isoniazid; Lung; Mice; Mice, Inbred BALB C; Mutation; Mycobacterium tuberculosis; Operon; Pyrazinamide; Time Factors; Tuberculosis, Pulmonary | 2010 |
[Phenotypic characterization of pyrazinamide-resistant Mycobacterium tuberculosis isolated in Poland].
Topics: Antitubercular Agents; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Phenotype; Poland; Pyrazinamide; Rifampin; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 2010 |
Human bovine tuberculosis - remains in the differential.
Topics: Adult; Antitubercular Agents; Drug Resistance, Bacterial; Female; Humans; Isoniazid; Male; Microbial Sensitivity Tests; Middle Aged; Mycobacterium bovis; Pyrazinamide; Radiography, Thoracic; Tomography, X-Ray Computed; Treatment Outcome; Tuberculosis | 2010 |
Mediastina Tuberculosis mass in a three-month-old boy.
Topics: Adrenal Cortex Hormones; Antibiotics, Antitubercular; Antitubercular Agents; Drug Therapy, Combination; Ethambutol; Follow-Up Studies; Humans; Infant; Isoniazid; Magnetic Resonance Imaging; Male; Mediastinal Diseases; Pyrazinamide; Rifampin; Time Factors; Treatment Outcome; Tuberculosis | 2010 |
A nodulo-ulcerative lesion on the nose.
Topics: Aged, 80 and over; Antitubercular Agents; Chronic Disease; Ethambutol; Female; Humans; Isoniazid; Lupus Vulgaris; Mycobacterium tuberculosis; Nose Diseases; Pyrazinamide; Rifampin; Skin Ulcer; Treatment Outcome; Tuberculosis, Pulmonary | 2010 |
Scrofula.
Topics: Adult; Antibiotics, Antitubercular; Antitubercular Agents; Ethambutol; Female; Humans; Isoniazid; Pyrazinamide; Rifampin; Sentinel Lymph Node Biopsy; Tuberculosis, Lymph Node | 2010 |
[A case of tuberculous pleurisy with transient new intra-pulmonary lesions during anti-tuberculosis therapy].
Topics: Antitubercular Agents; Ethambutol; Humans; Isoniazid; Lung; Male; Pyrazinamide; Rifampin; Tuberculosis, Pleural; Young Adult | 2010 |
[Culture and susceptibility testing of mycobacteria with VersaTREK].
Topics: Algorithms; Antitubercular Agents; Automation; Bacteriological Techniques; Culture Media; Ethambutol; Humans; Isoniazid; Manometry; Microbial Sensitivity Tests; Mycobacterium; Mycobacterium Infections; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Staining and Labeling; Streptomycin; Time Factors | 2011 |
Granulomatous lesion on the face successfully treated with antitubercular therapy.
Topics: Aged, 80 and over; Antibiotics, Antitubercular; Antitubercular Agents; Drug Therapy, Combination; Ethambutol; Facial Dermatoses; Female; Granuloma; Humans; Isoniazid; Mycobacterium Infections; Pyrazinamide; Rifampin; Skin Diseases, Bacterial | 2010 |
The use of the QuantiFERON-tuberculosis gold test in the diagnosis of ocular tuberculosis.
Topics: Adolescent; Antitubercular Agents; Drug Therapy, Combination; Ethambutol; Female; Fluorescein Angiography; Humans; Interferon-gamma Release Tests; Isoniazid; Pyrazinamide; Rifampin; Tuberculin Test; Tuberculosis, Ocular; Vision Disorders | 2010 |
Anterior segment optical coherence tomography findings of presumed intraocular tuberculosis.
Topics: Aged; Anterior Eye Segment; Antitubercular Agents; Cataract Extraction; Corneal Edema; Drug Therapy, Combination; Eye Diseases; Female; Humans; Isoniazid; Pyrazinamide; Rifampin; Tomography, Optical Coherence; Treatment Outcome; Tuberculosis | 2011 |
[A case of tuberculous lateral great adductor muscle abscess during treatment of miliary tuberculosis].
Topics: Abscess; Aged; Antitubercular Agents; Ethambutol; Female; Humans; Isoniazid; Mycobacterium tuberculosis; Pyrazinamide; Thigh; Tuberculosis, Miliary | 2010 |
Simultaneous determination of isoniazid, pyrazinamide, rifampicin and acetylisoniazid in human plasma by high-performance liquid chromatography.
Topics: Calibration; Chromatography, High Pressure Liquid; Humans; Isoniazid; Pyrazinamide; Rifampin; Sensitivity and Specificity | 2010 |
Comparative studies evaluating mouse models used for efficacy testing of experimental drugs against Mycobacterium tuberculosis.
Topics: Animals; Antitubercular Agents; Drug Therapy, Combination; Female; Isoniazid; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Tuberculosis | 2011 |
Effectiveness and safety of the schedules of short and long term treatment for tuberculous meningoencephalitis at two hospitals of Lima--Peru.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Drug Administration Schedule; Drug Therapy, Combination; Ethambutol; Female; Hospitals; Humans; Isoniazid; Male; Meningoencephalitis; Middle Aged; Peru; Pyrazinamide; Retrospective Studies; Rifampin; Treatment Outcome; Tuberculosis, Meningeal; Young Adult | 2011 |
A case of isoniazid-induced liver injury diagnosed by use of the DLST, and successful reintroduction of isoniazid for pleural tuberculosis.
Topics: Antitubercular Agents; Chemical and Drug Induced Liver Injury; Desensitization, Immunologic; Ethambutol; Female; Humans; Isoniazid; Lymphocyte Activation; Middle Aged; Pyrazinamide; Radiography; Retreatment; Rifampin; Tuberculosis, Pleural | 2011 |
[Sputum smear conversion during intensive TB treatment phase according to HIV status, in hospitalised patients in Togo].
Topics: Adult; Antitubercular Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; Ethambutol; Female; Follow-Up Studies; HIV Infections; HIV-1; Humans; Inpatients; Isoniazid; Male; Middle Aged; Mycobacterium tuberculosis; Prospective Studies; Pyrazinamide; Sampling Studies; Sputum; Togo; Tuberculosis, Pulmonary; Young Adult | 2011 |
Cutaneous tuberculosis mimicking erysipelas of the lower leg in a heart transplant recipient.
Topics: Antitubercular Agents; Erysipelas; Ethambutol; Heart Transplantation; Humans; Isoniazid; Leg; Opportunistic Infections; Pyrazinamide; Tuberculosis, Cutaneous | 2011 |
Location of anti-TB drugs and microstructural changes in organized surfactant media using optical properties.
Topics: Antitubercular Agents; Emulsions; Isoniazid; Polysorbates; Pyrazinamide; Pyrenes; Rifampin; Solubility; Surface-Active Agents | 2011 |
Molecular detection of mutations associated with first- and second-line drug resistance compared with conventional drug susceptibility testing of Mycobacterium tuberculosis.
Topics: Amikacin; Antitubercular Agents; Bacterial Proteins; Capreomycin; Ciprofloxacin; Ethambutol; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Rifampin | 2011 |
Distribution of three antituberculous drugs and their metabolites in different parts of pathological vertebrae with spinal tuberculosis.
Topics: Adult; Aged; Antitubercular Agents; Female; Humans; Isoniazid; Male; Middle Aged; Orthopedic Procedures; Pyrazinamide; Radiography; Rifampin; Spine; Tuberculosis, Spinal; Young Adult | 2011 |
Treatment of tuberculosis with rifamycin-containing regimens in immune-deficient mice.
Topics: Animals; Anti-Inflammatory Agents; Antibiotics, Antitubercular; Antitubercular Agents; Cortisone; Disease Models, Animal; Drug Administration Schedule; Drug Resistance, Bacterial; Drug Therapy, Combination; Female; Isoniazid; Lung; Mice; Mice, Inbred BALB C; Mice, Nude; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Secondary Prevention; Time Factors; Tuberculosis, Pulmonary | 2011 |
Mycobacteria infection in incomplete transverse myelitis is refractory to steroids: a pilot study.
Topics: Adult; Aged; Antitubercular Agents; Female; Humans; Isoniazid; Magnetic Resonance Imaging; Male; Methylprednisolone; Middle Aged; Myelitis, Transverse; Pilot Projects; Prospective Studies; Pyrazinamide; Rifampin; Spinal Cord; Tuberculosis | 2011 |
An apparently healthy young man with a peculiar-looking chest radiograph.
Topics: Adult; Antibiotics, Antitubercular; Drug Therapy, Combination; Ethambutol; Fever; HIV Seropositivity; Humans; Isoniazid; Male; Pleural Effusion; Pyrazinamide; Radiography; Rifampin; Tuberculosis, Pulmonary; Young Adult | 2011 |
[Pulmonary paragonimiasis].
Topics: Adult; Animals; Anthelmintics; Antitubercular Agents; Caulobacteraceae; Delayed Diagnosis; Ecuador; Ethambutol; Food Parasitology; Gram-Negative Bacterial Infections; Granuloma; Hemoptysis; Humans; Isoniazid; Lung Diseases, Parasitic; Male; Paragonimiasis; Pneumonia, Bacterial; Praziquantel; Pyrazinamide; Radiography; Rifampin; Spain; Tuberculosis, Pulmonary | 2011 |
Torticollis in mice intravenously infected with Mycobacterium tuberculosis.
Topics: Animals; Antitubercular Agents; Autopsy; Aza Compounds; Disease Models, Animal; Drug Therapy, Combination; Ear, Middle; Female; Fluoroquinolones; Injections, Intravenous; Isoniazid; Mice; Mice, Inbred BALB C; Moxifloxacin; Mycobacterium tuberculosis; Otitis Media; Pyrazinamide; Quinolines; Rifampin; Torticollis; Tuberculosis | 2011 |
Predicting outcomes and drug resistance with new standardised treatment.
Topics: Cohort Studies; Communicable Disease Control; Drug Resistance, Bacterial; Global Health; Humans; Isoniazid; Pyrazinamide; Recurrence; Rifampin; Treatment Outcome; Tuberculosis, Multidrug-Resistant | 2011 |
[Cutaneous reaction after pyrazinamide initiation].
Topics: Adult; Antitubercular Agents; Drug Combinations; Drug Eruptions; Drug Therapy, Combination; Dysgeusia; Flushing; Histamine H1 Antagonists; Humans; Isoniazid; Loratadine; Male; Pruritus; Pyrazinamide; Recurrence; Rifampin; Tryptases; Tuberculosis, Pulmonary; Vasodilation | 2011 |
BCG-induced lupus vulgaris complicated by squamous cell carcinoma in a 7-year-old child.
Topics: Antitubercular Agents; BCG Vaccine; Carcinoma, Squamous Cell; Child; Ethambutol; Humans; Isoniazid; Lupus Vulgaris; Lymphatic Metastasis; Male; Pyrazinamide; Rifampin; Skin Neoplasms; Treatment Outcome | 2011 |
Verrucous plaque on the thigh.
Topics: Adult; Antitubercular Agents; Ethambutol; Humans; Isoniazid; Male; Pyrazinamide; Rifampin; Thigh; Treatment Outcome; Tuberculosis, Cutaneous | 2011 |
The variable clinical presentation of tuberculosis otitis media and the importance of early detection.
Topics: Adolescent; Adult; Audiometry, Pure-Tone; Early Diagnosis; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Otitis Media, Suppurative; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis | 2011 |
Pulmonary tuberculosis in infants less than one year old: implications for early diagnosis.
Topics: Antitubercular Agents; Early Diagnosis; Family; Female; Hospitals, Pediatric; Hospitals, Teaching; Humans; Infant; Isoniazid; Male; Mycobacterium tuberculosis; Pyrazinamide; Retrospective Studies; Rifampin; Stomach; Tomography, X-Ray Computed; Tuberculin Test; Tuberculosis, Pulmonary; Turkey | 2011 |
Clinical response of newly diagnosed HIV seropositive & seronegative pulmonary tuberculosis patients with the RNTCP Short Course regimen in Pune, India.
Topics: Adult; Antitubercular Agents; Communicable Disease Control; Directly Observed Therapy; Enzyme-Linked Immunosorbent Assay; Ethambutol; HIV Seronegativity; HIV Seropositivity; Humans; India; Isoniazid; Middle Aged; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Pulmonary | 2011 |
Metabolic regulation of mycobacterial growth and antibiotic sensitivity.
Topics: Acetyl Coenzyme A; Anaerobiosis; Animals; Antitubercular Agents; Bacterial Load; Bacterial Proteins; Biosynthetic Pathways; Citric Acid Cycle; Drug Resistance, Bacterial; Ethambutol; Isoniazid; Lung; Mice; Mice, Inbred C57BL; Mutation; Mycobacterium tuberculosis; Pyrazinamide; Spleen; Stress, Physiological; Triglycerides; Tuberculosis, Pulmonary | 2011 |
Tuberculosis-associated chronic kidney disease.
Topics: Antitubercular Agents; Ethambutol; Fever; Humans; Isoniazid; Kidney Failure, Chronic; Male; Pyrazinamide; Renal Dialysis; Rifampin; Tuberculosis; Young Adult | 2011 |
Multifocal tuberculosis revealed by multiple cutaneous gummas in the immunocompetent.
Topics: Antitubercular Agents; Clavicle; Drug Therapy, Combination; Ethambutol; Humans; Immunocompetence; Isoniazid; Male; Morocco; Pyrazinamide; Rifampin; Skin Ulcer; Tuberculosis, Cutaneous; Tuberculosis, Osteoarticular; Tuberculosis, Pulmonary; Young Adult | 2011 |
Isoniazid-resistant intracranial tuberculoma treated with a combination of moxifloxacin and first-line anti-tuberculosis medication.
Topics: Antitubercular Agents; Aza Compounds; Biopsy; Brain; Cerebrospinal Fluid; Drug Resistance, Bacterial; Ethambutol; Female; Fluoroquinolones; Histocytochemistry; Humans; Isoniazid; Magnetic Resonance Imaging; Moxifloxacin; Mycobacterium tuberculosis; Pyrazinamide; Quinolines; Rifampin; Tomography, X-Ray Computed; Treatment Outcome; Tuberculoma, Intracranial; Tuberculosis, Multidrug-Resistant; Young Adult | 2011 |
Synergistic effect of antituberculosis drugs and azoles in vitro against Histoplasma capsulatum var. capsulatum.
Topics: Antitubercular Agents; Drug Combinations; Drug Interactions; Ethambutol; Fluconazole; Histoplasma; Isoniazid; Itraconazole; Pyrazinamide; Pyrimidines; Triazoles; Voriconazole | 2011 |
[A case of tuberculous peritonitis developed during chemotherapy for tuberculous pleurisy as paradoxical response].
Topics: Adenosine Deaminase; Adult; Antitubercular Agents; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Peritonitis, Tuberculous; Pleural Effusion; Pyrazinamide; Rifampin; Tomography, X-Ray Computed; Tuberculosis, Pleural | 2011 |
Acute liver failure in a pediatric patient with disseminated tuberculosis.
Topics: Antifungal Agents; Antitubercular Agents; Child; Coccidioidomycosis; Drug Therapy, Combination; Ethambutol; Fluconazole; Humans; Isoniazid; Liver Failure, Acute; Male; Pyrazinamide; Recovery of Function; Rifampin; Tuberculosis, Multidrug-Resistant | 2011 |
Primary nasal tuberculosis-a rare clinical entity.
Topics: Adult; Antitubercular Agents; Drug Therapy, Combination; Epistaxis; Female; Humans; Isoniazid; Nasal Obstruction; Pyrazinamide; Rhinitis; Rifampin; Sinusitis; Tuberculosis | 2011 |
[Lupus vulgaris].
Topics: Adult; Africa, Northern; Antitubercular Agents; Emigrants and Immigrants; Facial Dermatoses; Female; Humans; Isoniazid; Lupus Vulgaris; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Skin; Spain | 2012 |
Tuberculous damaged lung in a child.
Topics: Antitubercular Agents; Child; Drug Therapy, Combination; Ethambutol; Female; Granuloma; Humans; Isoniazid; Lung; Lung Neoplasms; Mycobacterium tuberculosis; Pyrazinamide; Radiography; Rifampin; Treatment Outcome; Tuberculosis, Hepatic; Tuberculosis, Pulmonary | 2011 |
Pyrazinamide-induced sideroblastic anemia.
Topics: 5-Aminolevulinate Synthetase; alpha-Thalassemia; Anemia, Sideroblastic; Antitubercular Agents; Aza Compounds; Bone Marrow; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Ethambutol; Female; Fluoroquinolones; Hemolysis; Humans; Isoniazid; Middle Aged; Moxifloxacin; Peritonitis, Tuberculous; Pyrazinamide; Pyridoxine; Quinolines; Rifampin | 2012 |
[Anti-tuberculosis chemotherapy and management of adverse reactions].
Topics: Aged, 80 and over; Antitubercular Agents; Child; Drug Administration Schedule; Drug Hypersensitivity; Ethambutol; Female; Humans; Isoniazid; Liver; Pregnancy; Pyrazinamide; Rifampin; Tuberculosis | 2011 |
[Immune reconstitution syndrome related to a Mycobacterium avium complex infection, revealed by a mono-adenitis].
Topics: Abscess; Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Antitubercular Agents; Axilla; Clarithromycin; Darunavir; Dideoxynucleosides; Enfuvirtide; Ethambutol; HIV Envelope Protein gp41; HIV-1; Humans; Immune Reconstitution Inflammatory Syndrome; Isoniazid; Lamivudine; Lymph Node Excision; Lymphadenitis; Male; Mycobacterium avium-intracellulare Infection; Peptide Fragments; Pyrazinamide; Rifampin; Ritonavir; Streptomycin; Sulfonamides | 2011 |
Clinical presentations and therapeutic effect of presumed choroidal tuberculosis.
Topics: Adolescent; Adult; Antitubercular Agents; Child; Choroid Diseases; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Retrospective Studies; Rifampin; Tuberculosis, Ocular; Young Adult | 2012 |
Dissolution testing of isoniazid, rifampicin, pyrazinamide and ethambutol tablets using near-infrared spectroscopy (NIRS) and multivariate calibration.
Topics: Antitubercular Agents; Calibration; Chromatography, High Pressure Liquid; Ethambutol; Isoniazid; Pyrazinamide; Rifampin; Solubility; Spectroscopy, Near-Infrared | 2012 |
Anti-tuberculosis drugs and human polymorphonuclear leukocyte functions.
Topics: Antitubercular Agents; Dose-Response Relationship, Drug; Drug Therapy, Combination; Ethambutol; Flow Cytometry; Humans; Isoniazid; Neutrophils; Phagocytosis; Pyrazinamide; Respiratory Burst; Rifampin; Staphylococcus aureus; Tuberculosis | 2011 |
Acute tuberculosis cutis miliaris disseminata in a patient with systemic lupus erythematosus.
Topics: Acute Disease; Antitubercular Agents; Drug Combinations; Female; Humans; Isoniazid; Lupus Erythematosus, Systemic; Middle Aged; Pyrazinamide; Rifampin; Steroids; Tuberculosis, Cutaneous; Tuberculosis, Miliary | 2011 |
Pharmacokinetic evaluation of the penetration of antituberculosis agents in rabbit pulmonary lesions.
Topics: Animals; Antitubercular Agents; Aza Compounds; Biological Availability; Disease Models, Animal; Drug Administration Schedule; Female; Fluoroquinolones; Granuloma; Humans; Isoniazid; Lung; Moxifloxacin; Mycobacterium tuberculosis; Pyrazinamide; Quinolines; Rabbits; Rifampin; Tissue Extracts; Tuberculosis, Pulmonary | 2012 |
[Scrofuloderma with hypersensitivity to rifampicin and pyrazinamide, treated with a combination therapy including ofloxacin].
Topics: Adult; Antibiotics, Antitubercular; Diagnosis, Differential; Drug Eruptions; Drug Therapy, Combination; Female; Humans; Injections, Intramuscular; Isoniazid; Ofloxacin; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Cutaneous | 2012 |
How useful is the Mantoux test in the diagnosis of doubtful cases of cutaneous tuberculosis?
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Biopsy; Child; Child, Preschool; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Predictive Value of Tests; Pyrazinamide; Rifampin; ROC Curve; Tuberculin Test; Tuberculosis, Cutaneous; Young Adult | 2011 |
Multidrug-resistant tuberculosis not due to noncompliance but to between-patient pharmacokinetic variability.
Topics: Antitubercular Agents; Computer Simulation; Drug Resistance, Multiple, Bacterial; Humans; Isoniazid; Medication Adherence; Models, Biological; Monte Carlo Method; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Tuberculosis, Multidrug-Resistant | 2011 |
Systemic exposure to rifampicin in patients with tuberculosis and advanced HIV disease during highly active antiretroviral therapy in Burkina Faso.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Antitubercular Agents; Burkina Faso; Chromatography, High Pressure Liquid; Ethambutol; Female; HIV Infections; Humans; Isoniazid; Male; Middle Aged; Plasma; Pyrazinamide; Rifampin; Tuberculosis | 2012 |
Cutaneous polyarteritis nodosa induced by Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Lung; Male; Middle Aged; Mycobacterium tuberculosis; Phenylpropionates; Polyarteritis Nodosa; Pyrazinamide; Radiography; Rifampin; Treatment Outcome; Tuberculosis, Cutaneous | 2012 |
When tuberculosis comes back: who develops recurrent tuberculosis in california?
Topics: Adult; Antitubercular Agents; California; Drug Therapy, Combination; Female; HIV; HIV Infections; Humans; Isoniazid; Male; Middle Aged; Public Health; Pyrazinamide; Recurrence; Rifampin; Tuberculosis, Pulmonary | 2011 |
[Sudden decrease in visual acuity and pulmonary infiltrates].
Topics: Adrenal Cortex Hormones; Antitubercular Agents; Ethambutol; Humans; Isoniazid; Laser Coagulation; Male; Neovascularization, Pathologic; Pyrazinamide; Radiography; Recurrence; Retinal Hemorrhage; Retinal Vasculitis; Rifampin; Tuberculosis, Pulmonary; Visual Acuity; Young Adult | 2012 |
Importance of confirming data on the in vivo efficacy of novel antibacterial drug regimens against various strains of Mycobacterium tuberculosis.
Topics: Animals; Antitubercular Agents; Disease Models, Animal; Drug Therapy, Combination; Female; Humans; Isoniazid; Lung; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Pulmonary | 2012 |
Therapeutic drug monitoring in the treatment of tuberculosis patients.
Topics: Adult; Aged; Alcoholism; Antibiotics, Antitubercular; Antitubercular Agents; Chromatography, High Pressure Liquid; Diabetes Complications; Diabetes Mellitus, Type 2; Drug Monitoring; Ethambutol; Humans; Isoniazid; Male; Middle Aged; Mycobacterium tuberculosis; Precision Medicine; Pyrazinamide; Recurrence; Rifampin; Schizophrenia; Sputum; Treatment Failure; Tuberculosis; Tuberculosis, Multidrug-Resistant | 2012 |
A case of isolated pancreatic tuberculosis mimicking pancreatic carcinoma.
Topics: Aged; Antitubercular Agents; Biopsy, Fine-Needle; Diagnosis, Differential; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Pancreatic Diseases; Pancreatic Neoplasms; Pyrazinamide; Rifampin; Tomography, X-Ray Computed; Tuberculosis | 2011 |
Clinical and anatomic features of female genital tuberculosis in 28 patients.
Topics: Adult; Antibiotics, Antitubercular; Antitubercular Agents; Drug Therapy, Combination; Female; Humans; Infertility, Female; Isoniazid; Middle Aged; Pelvic Pain; Pyrazinamide; Retrospective Studies; Rifampin; Tuberculosis, Female Genital; Young Adult | 2012 |
Drug treatment combined with BCG vaccination reduces disease reactivation in guinea pigs infected with Mycobacterium tuberculosis.
Topics: Animals; BCG Vaccine; Combined Modality Therapy; Female; Granuloma; Guinea Pigs; Isoniazid; Lung; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Tuberculosis | 2012 |
N-acetyltransferase 2 polymorphisms and risk of anti-tuberculosis drug-induced hepatotoxicity in Caucasians.
Topics: Adult; Antitubercular Agents; Arylamine N-Acetyltransferase; Case-Control Studies; Chemical and Drug Induced Liver Injury; Chi-Square Distribution; Female; Gene Frequency; Genetic Predisposition to Disease; Haplotypes; Humans; Isoniazid; Logistic Models; Male; Middle Aged; Odds Ratio; Phenotype; Polymorphism, Genetic; Pyrazinamide; Rifampin; Risk Assessment; Risk Factors; Tuberculosis; White People | 2011 |
Protective effect of curcumin, silymarin and N-acetylcysteine on antitubercular drug-induced hepatotoxicity assessed in an in vitro model.
Topics: Acetylcysteine; Antitubercular Agents; Cell Cycle; Cell Survival; Chemical and Drug Induced Liver Injury; Curcumin; Hep G2 Cells; Humans; Isoniazid; Membrane Potential, Mitochondrial; Protective Agents; Pyrazinamide; Silymarin | 2012 |
[An isolated case of appendicular tuberculosis].
Topics: Adolescent; Antitubercular Agents; Appendectomy; Appendicitis; Combined Modality Therapy; Drug Therapy, Combination; Humans; Isoniazid; Male; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Gastrointestinal | 2011 |
Minimally invasive posterior stabilization for treating spinal tuberculosis.
Topics: Adult; Antitubercular Agents; Bed Rest; Casts, Surgical; Combined Modality Therapy; Ethambutol; Humans; Isoniazid; Magnetic Resonance Imaging; Male; Minimally Invasive Surgical Procedures; Orthopedic Procedures; Pyrazinamide; Rifampin; Tomography, X-Ray Computed; Tuberculosis, Spinal | 2013 |
[Sternal tumour in a 46-year-old woman].
Topics: Antitubercular Agents; Biopsy; Carcinoma; Combined Modality Therapy; Diagnosis, Differential; Ethambutol; Female; Humans; Isoniazid; Lymphatic Diseases; Middle Aged; Mycobacterium tuberculosis; Osteolysis; Osteomyelitis; Pleural Effusion; Pleural Neoplasms; Pyrazinamide; Rifampin; Sputum; Sternum; Tomography, X-Ray Computed; Tuberculosis, Osteoarticular | 2012 |
Reduced antituberculosis drug concentrations in HIV-infected patients who are men or have low weight: implications for international dosing guidelines.
Topics: Adolescent; Adult; Age Factors; Aged; Antitubercular Agents; Birth Weight; Drug Resistance, Multiple; Female; HIV Infections; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Retrospective Studies; Rifampin; Sex Factors; Tuberculosis, Pulmonary; Young Adult | 2012 |
Sterilizing activities of novel combinations lacking first- and second-line drugs in a murine model of tuberculosis.
Topics: Animals; Antitubercular Agents; Drug Therapy, Combination; Female; Isoniazid; Mice; Mice, Inbred BALB C; Mycobacterium tuberculosis; Nitroimidazoles; Oxazolidinones; Pyrazinamide; Rifampin; Tuberculosis; Tuberculosis, Multidrug-Resistant | 2012 |
Outcomes among tuberculosis patients with isoniazid resistance in Georgia, 2007-2009.
Topics: Adult; Antitubercular Agents; Chi-Square Distribution; Drug Resistance, Bacterial; Drug Therapy, Combination; Ethambutol; Female; Georgia (Republic); Humans; Isoniazid; Logistic Models; Male; Microbial Sensitivity Tests; Middle Aged; Multivariate Analysis; Mycobacterium tuberculosis; Predictive Value of Tests; Pyrazinamide; Retrospective Studies; Rifampin; Risk Assessment; Risk Factors; Sputum; Time Factors; Treatment Outcome; Tuberculosis | 2012 |
Rifapentine is not more active than rifampin against chronic tuberculosis in guinea pigs.
Topics: Animals; Antitubercular Agents; Female; Guinea Pigs; Isoniazid; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Tuberculosis | 2012 |
Tubercular epitrochlear lymphadenopathy.
Topics: Antitubercular Agents; Child, Preschool; Drug Therapy, Combination; Elbow; Female; Humans; Isoniazid; Pyrazinamide; Rifampin; Tuberculosis, Lymph Node | 2012 |
Potential use of nitrate reductase as a biomarker for the identification of active and dormant inhibitors of Mycobacterium tuberculosis in a THP1 infection model.
Topics: Antitubercular Agents; Biomarkers; Cell Line, Tumor; Drug Discovery; Ethambutol; High-Throughput Screening Assays; Humans; Isoniazid; Leukemia, Monocytic, Acute; Macrophages; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nitrate Reductase; Pentachlorophenol; Pyrazinamide; Rifampin; Streptomycin | 2012 |
Extra-pulmonary primary multidrug-resistant tubercular lymphadenitis in an HIV negative patient.
Topics: Adult; Antitubercular Agents; Clarithromycin; Clofazimine; Cycloserine; Diagnosis, Differential; Drug Therapy, Combination; Ethambutol; Ethionamide; Female; HIV Seronegativity; Humans; Isoniazid; Kanamycin; Ofloxacin; Pyrazinamide; Rifampin; Tuberculosis, Lymph Node; Tuberculosis, Multidrug-Resistant | 2012 |
Host cell autophagy activated by antibiotics is required for their effective antimycobacterial drug action.
Topics: Animals; Antitubercular Agents; Autophagy; Autophagy-Related Protein 7; Cells, Cultured; Drosophila; Drosophila Proteins; Humans; Isoniazid; Macrophages; Mice; Mycobacterium marinum; Mycobacterium tuberculosis; Phagosomes; Pyrazinamide; Reactive Oxygen Species; Survival Analysis | 2012 |
Two-month regimen of isoniazid, rifampin and pirazinamid for latent tuberculosis infection.
Topics: Adult; Antitubercular Agents; Cohort Studies; Disease Progression; Drug Therapy, Combination; Female; Humans; Isoniazid; Latent Tuberculosis; Male; Patient Compliance; Portugal; Pyrazinamide; Retrospective Studies; Rifampin | 2012 |
Synthesis and antimycobacterial activity of some phthalimide derivatives.
Topics: Animals; Antitubercular Agents; Cell Line; Cell Survival; Drug Resistance, Multiple, Bacterial; Isoniazid; Mice; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Phthalimides; Pyrazinamide | 2012 |
[Paradoxical radiologic progression despite appropriate anti-tuberculous therapy].
Topics: Aged; Antitubercular Agents; Bronchoalveolar Lavage Fluid; Bronchoscopy; Ethambutol; Humans; Isoniazid; Male; Pyrazinamide; Rifampin; Tomography, X-Ray Computed; Treatment Outcome; Tuberculosis, Pulmonary | 2012 |
Dose-ranging comparison of rifampin and rifapentine in two pathologically distinct murine models of tuberculosis.
Topics: Animals; Antibiotics, Antitubercular; Antitubercular Agents; Disease Models, Animal; Drug Administration Schedule; Drug Therapy, Combination; Ethambutol; Isoniazid; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrazinamide; Random Allocation; Rifampin; Treatment Outcome; Tuberculosis, Pulmonary | 2012 |
Tubercular serpiginous-like choroiditis.
Topics: Antitubercular Agents; Choroiditis; Drug Combinations; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Tuberculosis, Ocular; Vision Disorders | 2011 |
[Retroperitoneal abscess in a patient under BCG treatment cause a bladder cancer].
Topics: Abdominal Abscess; Aged; Antitubercular Agents; BCG Vaccine; Humans; Isoniazid; Lung Neoplasms; Male; Mycobacterium tuberculosis; Pyrazinamide; Retroperitoneal Space; Tomography, X-Ray Computed; Tuberculosis; Urinary Bladder Neoplasms | 2012 |
Feasibility of a fixed-dose regimen of pyrazinamide and its impact on systemic drug exposure and liver safety in patients with tuberculosis.
Topics: Antitubercular Agents; Area Under Curve; Body Weight; Drug Dosage Calculations; Ethnicity; Female; Humans; Isoniazid; Liver; Male; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 2012 |
Management of and risk factors related to hepatotoxicity during tuberculosis treatment.
Topics: Adult; Age Factors; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Comorbidity; Drug Resistance, Bacterial; Drug Therapy, Combination; Female; Humans; Isoniazid; Liver Function Tests; Male; Pyrazinamide; Recurrence; Rifampin; Risk Factors; Sex Factors; Treatment Outcome; Tuberculosis, Pulmonary | 2012 |
Tuberculosis: an unusual cause of genital ulcer.
Topics: Adult; Antitubercular Agents; Extramarital Relations; Humans; Isoniazid; Male; Penis; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Cutaneous; Ulcer | 2012 |
[Bilateral tuberculous mastitis nulliparous patient, initially treated as idiopathic granulomatous mastitis].
Topics: Adult; Antitubercular Agents; Diagnostic Errors; Drug Therapy, Combination; Ethambutol; Female; Granulomatous Mastitis; Humans; Isoniazid; Mastitis; Methotrexate; Mycobacterium tuberculosis; Polymerase Chain Reaction; Prednisone; Pyrazinamide; Recurrence; Rifampin; Tuberculosis | 2012 |
[Cutaneous tuberculosis. Report of one case].
Topics: Antitubercular Agents; Biopsy; Diagnosis, Differential; Female; Humans; Isoniazid; Middle Aged; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Tuberculosis, Cutaneous | 2012 |
Pyrazinamide may improve fluoroquinolone-based treatment of multidrug-resistant tuberculosis.
Topics: Adult; Aged; Antitubercular Agents; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Female; Fluoroquinolones; Humans; Isoniazid; Longitudinal Studies; Male; Microbial Sensitivity Tests; Middle Aged; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Risk; Sputum; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 2012 |
Development and characterization of ligand-appended liposomes for multiple drug therapy for pulmonary tuberculosis.
Topics: Animals; Antitubercular Agents; Drug Delivery Systems; Drug Therapy, Combination; Humans; Isoniazid; Ligands; Liposomes; Mycobacterium tuberculosis; Pyrazinamide; Rats; Rats, Inbred Strains; Rifampin; Tuberculosis, Pulmonary | 2013 |
Lupus vulgaris in an immunocompromised patient.
Topics: Adult; Antitubercular Agents; Drug Therapy, Combination; Ethambutol; Female; Humans; Immunocompromised Host; Isoniazid; Kidney Transplantation; Lupus Vulgaris; Pyrazinamide; Rifampin | 2014 |
Modeling early bactericidal activity in murine tuberculosis provides insights into the activity of isoniazid and pyrazinamide.
Topics: Analysis of Variance; Animals; Antitubercular Agents; Colony Count, Microbial; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Antagonism; Drug Therapy, Combination; Early Medical Intervention; Isoniazid; Mice; Models, Biological; Pyrazinamide; Treatment Outcome; Tuberculosis | 2012 |
Improved consistency in dosing anti-tuberculosis drugs in Taipei, Taiwan.
Topics: Adult; Aged; Antitubercular Agents; Body Weight; Dose-Response Relationship, Drug; Drug Combinations; Drug Prescriptions; Drug Therapy, Combination; Female; Humans; Isoniazid; Male; Middle Aged; Practice Guidelines as Topic; Practice Patterns, Physicians'; Pyrazinamide; Rifampin; Taiwan; Tuberculosis; Young Adult | 2012 |
[Treatment of intractable tuberculous meningitis using intrathecal isoniazid administration and steroid pulse therapy; a report of two cases].
Topics: Adult; Antitubercular Agents; Dexamethasone; Drug Therapy, Combination; Ethambutol; Female; Humans; Injections, Spinal; Isoniazid; Male; Methylprednisolone; Middle Aged; Pulse Therapy, Drug; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Meningeal | 2012 |
Optimization of a reversed-phase-high-performance thin-layer chromatography method for the separation of isoniazid, ethambutol, rifampicin and pyrazinamide in fixed-dose combination antituberculosis tablets.
Topics: Antitubercular Agents; Chromatography, Reverse-Phase; Chromatography, Thin Layer; Ethambutol; Ethanol; Isoniazid; Pyrazinamide; Reproducibility of Results; Rifampin; Tablets | 2012 |
Formulation of Tyloxapol niosomes for encapsulation, stabilization and dissolution of anti-tubercular drugs.
Topics: Absorption; Antitubercular Agents; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Drug Compounding; Hydrogen-Ion Concentration; Isoniazid; Kinetics; Liposomes; Luminescence; Microscopy, Electron, Transmission; Particle Size; Polyethylene Glycols; Pyrazinamide; Pyrenes; Rifampin; Solubility; Spectroscopy, Fourier Transform Infrared; Surface-Active Agents | 2013 |
Intraretinal tuberculosis.
Topics: Administration, Oral; Adult; Antitubercular Agents; Drug Therapy, Combination; Ethambutol; Granuloma; Humans; Isoniazid; Male; Prednisolone; Pyrazinamide; Retinal Vasculitis; Rifampin; Tuberculosis, Ocular; Visual Acuity; Vitreous Hemorrhage | 2012 |
Indirect supportive evidence for diagnosis of tuberculosis-related uveitis: from the tuberculin skin test to the new interferon gamma release assays.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antitubercular Agents; Child; Drug Therapy, Combination; Ethambutol; Female; Glucocorticoids; Humans; Interferon-gamma Release Tests; Isoniazid; Male; Middle Aged; Prednisone; Prospective Studies; Pyrazinamide; Racial Groups; Radiography, Thoracic; Rifampin; Risk Factors; Sensitivity and Specificity; Spain; Surveys and Questionnaires; Tuberculin Test; Tuberculosis, Ocular; Urban Population; Uveitis; Young Adult | 2013 |
Outcomes of Category III DOTS treatment in immunocompetent patients with tuberculosis pleural effusion.
Topics: Adolescent; Adult; Antitubercular Agents; Directly Observed Therapy; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Immunocompetence; India; Isoniazid; Male; Pleural Effusion; Prospective Studies; Pyrazinamide; Recurrence; Rifampin; Treatment Outcome; Tuberculosis; Ultrasonography; Young Adult | 2012 |
Paucibacillary tubercular vulval ulcer in a sexually inactive pubertal girl: role of therapeutic trial.
Topics: Adolescent; Antitubercular Agents; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Pyrazinamide; Rifampin; Skin Ulcer; Tuberculin Test; Tuberculosis, Female Genital; Vulvar Diseases | 2012 |
[Directly observed treatment for tuberculosis in a Buenos Aires City hospital].
Topics: Adult; Antitubercular Agents; Argentina; Directly Observed Therapy; Drug Therapy, Combination; Ethambutol; Female; HIV Seronegativity; Humans; Isoniazid; Male; Pyrazinamide; Rifampin; Self Administration; Streptomycin; Treatment Outcome; Tuberculosis, Pulmonary | 2012 |
Pharmacokinetics of anti-tuberculosis drugs in Venezuelan children younger than 16 years of age: supportive evidence for the implementation of revised WHO dosing recommendations.
Topics: Acetyltransferases; Adolescent; Age Factors; Antitubercular Agents; Area Under Curve; Biological Availability; Child; Child, Preschool; Dose-Response Relationship, Drug; Ethambutol; Female; Humans; Infant; Isoniazid; Least-Squares Analysis; Male; Malnutrition; Polymorphism, Genetic; Practice Guidelines as Topic; Pyrazinamide; Rifampin; Tuberculosis; Venezuela; World Health Organization | 2012 |
Nosocomial transmission of extensively drug-resistant tuberculosis in a rural hospital in South Africa.
Topics: Adult; Antitubercular Agents; Cluster Analysis; Cross Infection; Drug Therapy, Combination; Ethambutol; Extensively Drug-Resistant Tuberculosis; Female; Genotype; HIV Infections; Hospitals, Rural; Humans; Isoniazid; Male; Mutation; Mycobacterium tuberculosis; Polymorphism, Restriction Fragment Length; Prevalence; Pyrazinamide; Retrospective Studies; Rifampin; Sequence Analysis, DNA; South Africa | 2013 |
Evaluation of tuberculosis underreporting in Greece through comparison with anti-tuberculosis drug consumption.
Topics: Antitubercular Agents; Epidemiological Monitoring; Ethambutol; Greece; Humans; Isoniazid; Latent Tuberculosis; Prescription Drugs; Pyrazinamide; Rifampin; Tuberculosis; Tuberculosis, Multidrug-Resistant | 2012 |
[Epidural abscess due to a Mycobacterium tuberculosis strain with primary resistance to isoniazid and ethambutol].
Topics: Antitubercular Agents; Cervical Vertebrae; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Epidural Abscess; Ethambutol; Humans; Isoniazid; Levofloxacin; Magnetic Resonance Imaging; Male; Middle Aged; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Streptomycin; Thoracic Vertebrae; Tuberculosis, Central Nervous System | 2012 |
Tuberculosis treatment survival of HIV positive TB patients on directly observed treatment short-course in Southern Ethiopia: a retrospective cohort study.
Topics: Adult; Anti-Retroviral Agents; Antitubercular Agents; Coinfection; Drug Administration Schedule; Female; HIV; HIV Infections; Humans; Isoniazid; Male; Mycobacterium tuberculosis; Proportional Hazards Models; Pyrazinamide; Rifampin; Survival Analysis; Treatment Outcome; Tuberculosis, Pulmonary | 2012 |
Impact of pharmacogenetic markers of CYP2B6, clinical factors, and drug-drug interaction on efavirenz concentrations in HIV/tuberculosis-coinfected patients.
Topics: Adenine; Adolescent; Adult; Alkynes; Anti-HIV Agents; Antitubercular Agents; Aryl Hydrocarbon Hydroxylases; Benzoxazines; Cyclopropanes; Cytochrome P-450 CYP2B6; Drug Interactions; Ethambutol; Female; Genotype; HIV Infections; Humans; Isoniazid; Lamivudine; Male; Middle Aged; Organophosphonates; Oxidoreductases, N-Demethylating; Pharmacogenetics; Polymorphism, Single Nucleotide; Pyrazinamide; Reverse Transcriptase Inhibitors; Rifampin; Tenofovir; Tuberculosis; Young Adult | 2013 |
[Anti-mycobacteria drugs therapy for periductal mastitis with fistula].
Topics: Adolescent; Adult; Anti-Bacterial Agents; Drug Therapy, Combination; Ethambutol; Female; Fistula; Humans; Isoniazid; Mastitis; Nontuberculous Mycobacteria; Pyrazinamide; Retrospective Studies; Rifampin; Young Adult | 2012 |
Inadequate therapeutic response to a recommended antituberculosis fixed-dose combination regimen in an overweight patient with Mycobacterium bovis infection.
Topics: Adult; Antitubercular Agents; Drug Combinations; Drug Monitoring; Drug Therapy, Combination; Humans; Isoniazid; Levofloxacin; Male; Mycobacterium bovis; Ofloxacin; Overweight; Practice Guidelines as Topic; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Lymph Node | 2013 |
A pregnant woman with dyspnoea, fever & decreased vision.
Topics: Adult; Antitubercular Agents; Choroid Diseases; Ethambutol; Female; Humans; Isoniazid; Pregnancy; Pregnancy Outcome; Pyrazinamide; Radiography; Rifampin; Treatment Outcome; Tuberculosis, Miliary | 2012 |
[Thyroid tuberculosis; a rare cause of compressive goiter].
Topics: Antitubercular Agents; Biopsy; Combined Modality Therapy; Deglutition Disorders; Drainage; Ethambutol; Goiter; Hormone Replacement Therapy; Humans; Hypothyroidism; Isoniazid; Lymphatic Diseases; Male; Middle Aged; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection; Pyrazinamide; Rifampin; Thyroiditis; Thyroxine; Tuberculosis, Endocrine | 2013 |
[A case of tuberculous peritonitis in a hemodialysis patient revealed by severe diarrhea and stomachache].
Topics: Abdominal Pain; Antitubercular Agents; Biomarkers; CA-125 Antigen; Diagnosis, Differential; Diarrhea; Drug Combinations; Ethambutol; Female; Humans; Isoniazid; Middle Aged; Peritonitis, Tuberculous; Pyrazinamide; Receptors, Interleukin-2; Renal Dialysis; Rifampin; Treatment Outcome | 2013 |
Isoniazid- and streptomycin-resistant miliary tuberculosis complicated by intracranial tuberculoma in a Japanese infant.
Topics: Antitubercular Agents; Drug Substitution; Drug Therapy, Combination; Ethambutol; Ethionamide; Female; Humans; Infant; Isoniazid; Microbial Sensitivity Tests; Pyrazinamide; Radiography, Thoracic; Rifampin; Streptomycin; Treatment Outcome; Tuberculoma, Intracranial; Tuberculosis, Miliary; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 2013 |
[Primary sinonasal tuberculosis: apropos of a case].
Topics: Aged; Antitubercular Agents; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Maxillary Sinusitis; Mycobacterium tuberculosis; Nasal Obstruction; Nasal Polyps; Pyrazinamide; Rifampin; Tuberculosis | 2013 |
Characterization of mutations in multi- and extensive drug resistance among strains of Mycobacterium tuberculosis clinical isolates in Republic of Korea.
Topics: Acetyltransferases; Amidohydrolases; Amikacin; Antigens, Bacterial; Bacterial Proteins; Capreomycin; Catalase; DNA Gyrase; DNA Primers; DNA-Directed RNA Polymerases; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Ethambutol; Fluoroquinolones; Genetic Loci; Humans; Isoniazid; Kanamycin; Mutation; Mycobacterium tuberculosis; Ofloxacin; Oxidoreductases; Pentosyltransferases; Polymerase Chain Reaction; Promoter Regions, Genetic; Pyrazinamide; Republic of Korea; Rifampin; Sequence Analysis, DNA; Streptomycin; Tuberculosis, Multidrug-Resistant | 2013 |
Evaluation of antihepatotoxic potential of Solanum xanthocarpum fruit extract against antitubercular drugs induced hepatopathy in experimental rodents.
Topics: Animals; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Female; Fruit; Gastrointestinal Agents; Histocytochemistry; Isoniazid; Liver; Liver Function Tests; Male; Mice; Plant Extracts; Plasma; Pyrazinamide; Rats, Wistar; Rifampin; Solanum | 2012 |
Factors associated with the rapid implementation process of the fixed-dose combination RHZE tuberculosis regimen in Brazil: an ecological study.
Topics: Antitubercular Agents; Brazil; Drug Combinations; Ethambutol; Health Plan Implementation; Humans; Incidence; Isoniazid; Population Density; Practice Guidelines as Topic; Pyrazinamide; Rifampin; Time Factors; Tuberculosis | 2013 |
Primary gingival tuberculosis diagnosis: a difficult endeavor.
Topics: Antibiotics, Antitubercular; Antitubercular Agents; Diagnosis, Differential; Female; Gingival Diseases; Gingival Hemorrhage; Gingivitis; Humans; Isoniazid; Pyrazinamide; Rifampin; Tuberculosis, Oral; Young Adult | 2013 |
Pharmacokinetics of first-line tuberculosis drugs in Tanzanian patients.
Topics: Adult; Antitubercular Agents; Ethambutol; Female; Humans; Isoniazid; Male; Pyrazinamide; Rifampin; Tanzania; Treatment Outcome; Tuberculosis, Pulmonary | 2013 |
[Clinical evaluation of a line probe assay kit for the identification of Mycobacterium species and detection of drug-resistant Mycobacterium tuberculosis].
Topics: Antitubercular Agents; Drug Resistance, Multiple, Bacterial; Humans; Isoniazid; Levofloxacin; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Rifampin | 2013 |
Age, nutritional status and INH acetylator status affect pharmacokinetics of anti-tuberculosis drugs in children.
Topics: Acetylation; Age Factors; Antitubercular Agents; Child; Child, Preschool; Chromatography, High Pressure Liquid; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; India; Infant; Isoniazid; Male; Multivariate Analysis; Nutritional Status; Phenotype; Pyrazinamide; Regression Analysis; Rifampin; Time Factors; Treatment Outcome; Tuberculosis | 2013 |
Isoniazid, rifampin, and pyrazinamide plasma concentrations in relation to treatment response in Indonesian pulmonary tuberculosis patients.
Topics: Adult; Antitubercular Agents; Area Under Curve; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Indonesia; Isoniazid; Lung; Male; Middle Aged; Prospective Studies; Pyrazinamide; Rifampin; Risk Factors; Sputum; Time Factors; Treatment Outcome; Tuberculosis, Pulmonary | 2013 |
Development and validation of a hydrophilic interaction liquid chromatography-tandem mass spectrometry method for the simultaneous determination of five first-line antituberculosis drugs in plasma.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antitubercular Agents; Child; Chromatography, Liquid; Drug Monitoring; Ethambutol; Female; Humans; Hydrophobic and Hydrophilic Interactions; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Streptomycin; Tandem Mass Spectrometry; Tuberculosis; Young Adult | 2013 |
Severe hyponatremia and MRI point to diagnosis of tuberculous meningitis in the Southwest USA.
Topics: Adult; Antitubercular Agents; Drug Therapy, Combination; Ethambutol; Female; Humans; Hyponatremia; Isoniazid; Magnetic Resonance Imaging; Pyrazinamide; Rifampin; Southwestern United States; Tuberculosis, Meningeal; Young Adult | 2013 |
A breathtaking response to tuberculosis therapy.
Topics: Adult; Antitubercular Agents; Disease Progression; Dyspnea; Ethambutol; Female; Humans; Isoniazid; Mediastinum; Pericarditis, Tuberculous; Pyrazinamide; Radiography; Rifampin; Tuberculosis, Lymph Node | 2013 |
Serum drug concentrations predictive of pulmonary tuberculosis outcomes.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Area Under Curve; Female; Humans; Isoniazid; Male; Microbial Sensitivity Tests; Middle Aged; Mycobacterium tuberculosis; Prospective Studies; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Pulmonary; Young Adult | 2013 |
Estimation of content of anti-TB drugs supplied at centres of the Revised National TB Control Programme in Tamil Nadu, India.
Topics: Antitubercular Agents; Cycloserine; Drug Stability; Drug Storage; Drug Therapy, Combination; Ethambutol; Ethionamide; Humans; India; Isoniazid; Levofloxacin; Ofloxacin; Pyrazinamide; Rifampin; Spectrophotometry; Tuberculosis | 2013 |
Therapeutic potential of thymoquinone against anti-tuberculosis drugs induced liver damage.
Topics: Analysis of Variance; Animals; Antitubercular Agents; Benzoquinones; Blood Chemical Analysis; Chemical and Drug Induced Liver Injury; Ethambutol; Female; Isoniazid; Kidney; Lipid Peroxidation; Lipids; Liver; Liver Function Tests; Pyrazinamide; Rats; Rats, Sprague-Dawley; Rifampin; Superoxide Dismutase | 2013 |
Plasma concentrations of isoniazid and rifampin are decreased in adult pulmonary tuberculosis patients with diabetes mellitus.
Topics: Adult; Antitubercular Agents; Biological Availability; Diabetes Mellitus, Type 2; Drug Administration Schedule; Drug Dosage Calculations; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 2013 |
Immunotherapeutic efficacy of recombinant Mycobacterium smegmatis expressing Ag85B-ESAT6 fusion protein against persistent tuberculosis infection in mice.
Topics: Acyltransferases; Animals; Antigens, Bacterial; Antitubercular Agents; Bacteria; Bacterial Load; Bacterial Proteins; Combined Modality Therapy; Disease Models, Animal; Female; Humans; Interferon-gamma; Interleukin-2; Isoniazid; Leukocytes, Mononuclear; Lung; Mice, Inbred C57BL; Mycobacterium smegmatis; Pyrazinamide; Recombinant Fusion Proteins; Spleen; T-Lymphocytes, Cytotoxic; Treatment Outcome; Tuberculosis; Tuberculosis Vaccines; Vaccines, Synthetic | 2014 |
[Treatment of presumed tuberculous uveitis affecting the posterior segment: diagnostic confirmation and long term outcomes].
Topics: Anti-Bacterial Agents; Antitubercular Agents; Drug Therapy, Combination; Humans; Immunocompromised Host; Immunosuppressive Agents; Isoniazid; Panuveitis; Pyrazinamide; Recurrence; Remission Induction; Retrospective Studies; Rifampin; Treatment Outcome; Tuberculosis, Ocular; Uveitis, Posterior | 2013 |
A case of skin and lung tuberculosis: diagnostic difficulties.
Topics: Antitubercular Agents; Bronchitis; Bronchoalveolar Lavage Fluid; Bronchoscopy; CD4-CD8 Ratio; Diagnosis, Differential; Diagnostic Errors; Drug Therapy, Combination; Ethambutol; Facial Dermatoses; Female; Humans; Isoniazid; Middle Aged; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Sarcoidosis; Sputum; Tuberculosis, Cutaneous; Tuberculosis, Pulmonary | 2013 |
Paediatric tubercular spinal abscess involving the dorsal, lumbar and sacral regions and causing spinal cord compression.
Topics: Adolescent; Antitubercular Agents; Drug Therapy, Combination; Epidural Abscess; Humans; Isoniazid; Laminectomy; Lumbosacral Region; Male; Mycobacterium tuberculosis; Pyrazinamide; Rare Diseases; Rifampin; Spinal Cord Compression; Thoracic Vertebrae; Treatment Outcome; Tuberculin Test; Tuberculosis, Spinal | 2013 |
Lupus Vulgaris Erythematoides: report of a patient initially misdiagnosed as dermatitis.
Topics: Adrenal Cortex Hormones; Aged, 80 and over; Anti-Bacterial Agents; Antitubercular Agents; Biopsy; Calcineurin Inhibitors; Dermis; Diagnostic Errors; Drug Therapy, Combination; Eczema; Erythema; Facial Dermatoses; Female; Histiocytosis, Langerhans-Cell; Humans; Immunosuppressive Agents; Isoniazid; Lupus Vulgaris; Mycobacterium tuberculosis; Necrosis; Nose Diseases; Pyrazinamide; Rifampin | 2013 |
Olfactory disturbance related to pyrazinamide.
Topics: Antitubercular Agents; Drug Combinations; Humans; Isoniazid; Male; Middle Aged; Olfaction Disorders; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 2014 |
Thioridazine pharmacokinetic-pharmacodynamic parameters "Wobble" during treatment of tuberculosis: a theoretical basis for shorter-duration curative monotherapy with congeners.
Topics: Antipsychotic Agents; Antitubercular Agents; Colony Count, Microbial; Computer Simulation; Drug Administration Schedule; Drug Design; Drug Repositioning; Drug Resistance, Bacterial; Humans; Infusions, Intravenous; Isoniazid; Latent Tuberculosis; Microbial Sensitivity Tests; Models, Statistical; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Thioridazine; Time Factors | 2013 |
[Primary penile tuberculosis].
Topics: Antitubercular Agents; Drug Therapy, Combination; Ethambutol; Humans; Immunocompromised Host; Isoniazid; Male; Middle Aged; Penile Diseases; Pyrazinamide; Rifampin; Skin Ulcer; Tuberculosis, Male Genital; Vitiligo | 2013 |
Pharmacokinetics and serum concentrations of antimycobacterial drugs in adult Turkish patients.
Topics: Administration, Oral; Adolescent; Adult; Aged; Antitubercular Agents; Area Under Curve; Directly Observed Therapy; Drug Monitoring; Ethambutol; Female; Half-Life; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary; Turkey; Young Adult | 2013 |
Comparison of time to positive and colony counting in an early bactericidal activity study of anti-tuberculosis treatment.
Topics: Adult; Antitubercular Agents; Automation, Laboratory; Colony Count, Microbial; Drug Monitoring; Drug Therapy, Combination; Ethambutol; Feasibility Studies; Female; Humans; Isoniazid; Male; Mycobacterium tuberculosis; Predictive Value of Tests; Prospective Studies; Pyrazinamide; Rifampin; Sputum; Time Factors; Treatment Outcome; Tuberculosis, Pulmonary; Uganda; Young Adult | 2013 |
Optimization of SABRE for polarization of the tuberculosis drugs pyrazinamide and isoniazid.
Topics: Antitubercular Agents; Electromagnetic Fields; Hydrogen; Isoniazid; Magnetic Resonance Spectroscopy; Pyrazinamide; Solvents | 2013 |
Anti‑tuberculosis drugs decrease viability and stimulate the expression of chondrocyte marker genes in human nucleus pulposus cells.
Topics: Adolescent; Aggrecans; Antitubercular Agents; Cell Survival; Cells, Cultured; Collagen Type I; Collagen Type I, alpha 1 Chain; Collagen Type II; Ethambutol; Glycosaminoglycans; Humans; Intervertebral Disc; Isoniazid; Pyrazinamide; Rifampin; RNA, Messenger; SOX9 Transcription Factor; Transforming Growth Factor beta1; Young Adult | 2014 |
Clonal expansion of Mycobacterium tuberculosis isolates and coexisting drug resistance in patients newly diagnosed with pulmonary tuberculosis in Hanoi, Vietnam.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antitubercular Agents; Clone Cells; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Ethambutol; Female; Humans; Isoniazid; Male; Microbial Sensitivity Tests; Middle Aged; Mutation; Mycobacterium tuberculosis; Operon; Phylogeny; Polymorphism, Restriction Fragment Length; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Vietnam | 2013 |
Isoniazid, rifampicin and pyrazinamide plasma concentrations 2 and 6 h post dose in patients with pulmonary tuberculosis.
Topics: Adult; Aged; Antitubercular Agents; Chromatography, High Pressure Liquid; Drug Monitoring; Drug Therapy, Combination; Female; Hospitals, University; Humans; Iran; Isoniazid; Male; Middle Aged; Pyrazinamide; Reference Standards; Reference Values; Rifampin; Tertiary Care Centers; Treatment Failure; Tuberculosis, Pulmonary | 2013 |
[Thrombocytopenia induced by rifampicin not previously sensitized: a case presentation].
Topics: Adult; Antibiotics, Antitubercular; Ethambutol; Female; Humans; Immunization; Isoniazid; Purpura, Thrombocytopenic, Idiopathic; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 2013 |
[A clinical investigation of seven patients with pulmonary tuberculosis who developed mixed liver injury during oral anti-tuberculosis treatment].
Topics: Aged; Aged, 80 and over; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 2013 |
Strategy to limit sampling of antituberculosis drugs instead of determining concentrations at two hours postingestion in relation to treatment response.
Topics: Antitubercular Agents; Female; Humans; Isoniazid; Male; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 2014 |
Reply to "strategy to limit sampling of antituberculosis drugs instead of determining concentrations at two hours postingestion in relation to treatment response".
Topics: Antitubercular Agents; Female; Humans; Isoniazid; Male; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 2014 |
[Antimicrobial resistance in tuberculosis].
Topics: Antitubercular Agents; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Ethambutol; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Spain; Streptomycin; Tuberculosis, Pulmonary | 2013 |
Probing location of anti-TB drugs loaded in Brij 96 microemulsions using thermoanalytical and photophysical approach.
Topics: 2,2'-Dipyridyl; Antitubercular Agents; Calorimetry, Differential Scanning; Coordination Complexes; Drug Carriers; Drug Compounding; Drug Stability; Emulsions; Fluorescence Polarization; Fluorescent Dyes; Hydrophobic and Hydrophilic Interactions; Isoniazid; Models, Chemical; Oxazines; Plant Oils; Polyethylene Glycols; Pyrazinamide; Rifampin; Solubility; Spectrometry, Fluorescence; Water | 2014 |
Correlation of plasma anti-tuberculosis drug levels with subsequent development of hepatotoxicity.
Topics: Adult; Antitubercular Agents; Area Under Curve; Case-Control Studies; Chemical and Drug Induced Liver Injury; Drug Administration Schedule; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Isoniazid; Male; Metabolic Clearance Rate; Prospective Studies; Pyrazinamide; Rifampin; Risk Factors; Tuberculosis | 2014 |
The incidence of liver injury in Uyghur patients treated for TB in Xinjiang Uyghur autonomous region, China, and its association with hepatic enzyme polymorphisms nat2, cyp2e1, gstm1 and gstt1.
Topics: Adult; Antitubercular Agents; Arylamine N-Acetyltransferase; Chemical and Drug Induced Liver Injury; China; Cross-Sectional Studies; Cytochrome P-450 CYP2E1; Drug Therapy, Combination; Ethambutol; Female; Gene Frequency; Genetic Association Studies; Glutathione Transferase; Humans; Incidence; Isoniazid; Male; Middle Aged; Polymorphism, Single Nucleotide; Prevalence; Pyrazinamide; Rifampin; Sex Distribution; Tuberculosis, Pulmonary; Young Adult | 2014 |
Fatal suicidal poisoning with antituberculosis agents with ST elevation and acute coronary syndrome symptoms--a case report.
Topics: Acute Coronary Syndrome; Antitubercular Agents; Drug Overdose; Echocardiography; Ethanol; Fatal Outcome; Humans; Isoniazid; Ketoprofen; Male; Pyrazinamide; Rifampin; Shock, Cardiogenic; Suicide; Young Adult | 2013 |
Hepatoprotective potential of Cassia auriculata roots on ethanol and antitubercular drug-induced hepatotoxicity in experimental models.
Topics: Animals; Antioxidants; Antitubercular Agents; Cassia; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Female; India; Isoniazid; Male; Medicine, Traditional; Plant Extracts; Plant Roots; Pyrazinamide; Rats; Rats, Wistar; Rifampin; Silymarin | 2014 |
Population pharmacokinetics of rifampicin, pyrazinamide and isoniazid in children with tuberculosis: in silico evaluation of currently recommended doses.
Topics: Antitubercular Agents; Child; Child, Preschool; Electronic Data Processing; Female; Humans; Infant; Isoniazid; Male; Models, Statistical; Pyrazinamide; Rifampin; South Africa; Tuberculosis | 2014 |
Esophageal anthracosis with tuberculous lymphadenitis confirmed on transesophageal endoscopic ultrasound-guided fine-needle aspiration.
Topics: Aged; Anthracosis; Antitubercular Agents; Chest Pain; Drug Therapy, Combination; Endoscopic Ultrasound-Guided Fine Needle Aspiration; Esophagus; Ethambutol; Female; Humans; Isoniazid; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Lymph Node; Weight Loss | 2014 |
[Hypothermia due to anti-tuberculosis drugs: first case].
Topics: Aged; Antitubercular Agents; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Ethambutol; Female; Humans; Hypothermia; Isoniazid; Pyrazinamide; Tuberculosis, Pulmonary; Vomiting | 2014 |
Multidrug-resistant tuberculosis in Western Australia, 1998-2012.
Topics: Adolescent; Adult; Antitubercular Agents; Aza Compounds; Case-Control Studies; Child; Drug Therapy, Combination; Ethambutol; Female; Fluoroquinolones; Hospitalization; Humans; Isoniazid; Male; Middle Aged; Moxifloxacin; Mycobacterium tuberculosis; Pyrazinamide; Quinolines; Retrospective Studies; Risk Factors; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Western Australia; Young Adult | 2014 |
[Mechanism of hepatocyte apoptosis in experimental toxic liver injury].
Topics: Animals; Apoptosis; Caspase 3; Caspase 8; Chemical and Drug Induced Liver Injury; fas Receptor; Gene Expression Regulation; Hepatocytes; Isoniazid; Protective Agents; Pyrazinamide; Rats; S-Adenosylmethionine; Signal Transduction; Tumor Suppressor Protein p53 | 2013 |
An unusual cause of breast lump: isolated tuberculosis of the breast.
Topics: Antitubercular Agents; Biopsy, Fine-Needle; Breast Diseases; Ethambutol; Female; Humans; Isoniazid; Middle Aged; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Tuberculosis | 2014 |
Isoniazid mediates the CYP2B6*6 genotype-dependent interaction between efavirenz and antituberculosis drug therapy through mechanism-based inactivation of CYP2A6.
Topics: Alkynes; Antitubercular Agents; Benzoxazines; Cyclopropanes; Cytochrome P-450 CYP2A6; Cytochrome P-450 CYP2B6; Drug Interactions; Enzyme Activation; Ethambutol; Humans; Hydroxylation; Isoniazid; Microsomes, Liver; Pyrazinamide; Rifampin | 2014 |
Cervical lymphadenopathy--pitfalls of blind antitubercular treatment.
Topics: Adolescent; Adult; Antitubercular Agents; Biopsy; Diagnostic Errors; Ethambutol; Female; Histiocytic Necrotizing Lymphadenitis; Hodgkin Disease; Humans; India; Isoniazid; Lymphoma, Non-Hodgkin; Male; Middle Aged; Pyrazinamide; Rifampin; Tuberculosis; Tuberculosis, Multidrug-Resistant; Young Adult | 2014 |
Simvastatin increases the in vivo activity of the first-line tuberculosis regimen.
Topics: Animals; Antitubercular Agents; Bacterial Load; Cell Line; Colony Count, Microbial; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Female; Isoniazid; Lung; Macrophages; Mice, Inbred BALB C; Pyrazinamide; Rifampin; Simvastatin; Treatment Outcome; Tuberculosis | 2014 |
Prevalence of extended treatment in pulmonary tuberculosis patients receiving first-line therapy and its association with recurrent tuberculosis in Beijing, China.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antitubercular Agents; China; Cohort Studies; Cost of Illness; Drug Combinations; Ethambutol; Female; Health Care Costs; Humans; Isoniazid; Male; Middle Aged; Prevalence; Pyrazinamide; Recurrence; Retrospective Studies; Rifampin; Tuberculosis, Pulmonary; Young Adult | 2014 |
Sterilizing activity of thioridazine in combination with the first-line regimen against acute murine tuberculosis.
Topics: Animals; Antitubercular Agents; Disease Models, Animal; Drug Therapy, Combination; Female; Isoniazid; Lung; Mice; Mice, Inbred BALB C; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Thioridazine; Tuberculosis, Pulmonary | 2014 |
Association of serum levels of iron, copper, and zinc, and inflammatory markers with bacteriological sputum conversion during tuberculosis treatment.
Topics: Adult; Antitubercular Agents; Biomarkers; C-Reactive Protein; Copper; Ethambutol; Hemoglobins; Host-Pathogen Interactions; Humans; Inflammation; Iron; Isoniazid; Male; Middle Aged; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Serum Albumin; Serum Globulins; Sputum; Time Factors; Treatment Outcome; Tuberculosis, Pulmonary; Zinc | 2014 |
Novel bronchoscopic balloon dilation for patients with bronchostenosis caused by bronchial tuberculosis: a case report.
Topics: Antitubercular Agents; Bronchial Diseases; Bronchoscopy; Constriction, Pathologic; Dilatation; Ethambutol; Female; Humans; Isoniazid; Lung; Pyrazinamide; Radiography; Rifampin; Treatment Outcome; Tuberculosis, Pulmonary; Young Adult | 2014 |
Genotoxic effects of some antituberculosis drugs and mixtures in rats.
Topics: Animals; Antitubercular Agents; DNA Damage; Drug Combinations; Ethambutol; Isoniazid; Kidney; Liver; Male; Pyrazinamide; Rats; Rifampin | 2015 |
Isoniazid, pyrazinamide and rifampicin content variation in split fixed-dose combination tablets.
Topics: Chemistry, Pharmaceutical; Drug Combinations; Humans; Isoniazid; Pyrazinamide; Quality Control; Rifampin; Tablets; Tuberculosis, Pulmonary | 2014 |
Disseminated Mycobacterium celatum disease with prolonged pulmonary involvement.
Topics: Aged; Anti-Bacterial Agents; Azithromycin; Ciprofloxacin; Clarithromycin; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Lung; Lung Diseases; Mycobacterium; Mycobacterium Infections; Pyrazinamide; Radiography | 2014 |
Pulmonary tuberculoma in a patient with chronic hepatitis C: a clinical pitfall in the treatment strategy.
Topics: Antitubercular Agents; Antiviral Agents; DNA, Viral; Drug Therapy, Combination; Female; Follow-Up Studies; Hepacivirus; Hepatitis C, Chronic; Humans; Image-Guided Biopsy; Isoniazid; Lung; Middle Aged; Mycobacterium tuberculosis; Practice Guidelines as Topic; Pyrazinamide; Rifampin; Tomography, X-Ray Computed; Tuberculoma; Tuberculosis, Pulmonary | 2014 |
False-positive rifampicin resistance on Xpert® MTB/RIF caused by a silent mutation in the rpoB gene.
Topics: Aged; Amikacin; Amino Acid Sequence; Antibiotics, Antitubercular; Bacterial Proteins; DNA-Directed RNA Polymerases; Drug Resistance, Multiple, Bacterial; Ethambutol; Ethionamide; Fluoroquinolones; Genotype; Humans; Isoniazid; Male; Molecular Sequence Data; Moxifloxacin; Mutation; Mycobacterium tuberculosis; Phenotype; Pyrazinamide; Rifampin; Sensitivity and Specificity; Sputum; Tuberculosis, Pulmonary | 2014 |
Drug resistance of Mycobacterium tuberculosis isolates from tuberculosis lymphadenitis patients in Ethiopia.
Topics: Antitubercular Agents; Biopsy, Fine-Needle; Cross-Sectional Studies; Drug Resistance, Multiple, Bacterial; Ethambutol; Ethiopia; Female; Humans; Isoniazid; Male; Mycobacterium tuberculosis; Prospective Studies; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Lymph Node | 2014 |
Thioridazine for treatment of tuberculosis: promises and pitfalls.
Topics: Animals; Antitubercular Agents; Female; Isoniazid; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Thioridazine; Tuberculosis | 2014 |
Investigating gender disparities in the profile and treatment outcomes of tuberculosis in Ebonyi state, Nigeria.
Topics: Adult; Antitubercular Agents; Cohort Studies; Coinfection; Ethambutol; Female; Health Status Disparities; HIV Infections; Humans; Isoniazid; Male; Middle Aged; Nigeria; Pyrazinamide; Retrospective Studies; Rifampin; Rural Population; Sex Factors; Streptomycin; Time Factors; Treatment Outcome; Tuberculosis; Tuberculosis, Pulmonary; Urban Population; Young Adult | 2015 |
Re-emphasizing Thygeson's warning: conjunctival phlyctenulosis as presenting sign of impending clinical tuberculosis.
Topics: Antitubercular Agents; Blood Sedimentation; Child; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Keratoconjunctivitis; Pyrazinamide; Rifampin; Tuberculosis, Lymph Node; Tuberculosis, Ocular | 2014 |
Potential of multisyringe chromatography for the on-line monitoring of the photocatalytic degradation of antituberculosis drugs in aqueous solution.
Topics: Antitubercular Agents; Catalysis; Chromatography, High Pressure Liquid; Environmental Monitoring; Equipment Design; Isoniazid; Oxidation-Reduction; Photochemical Processes; Pyrazinamide; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Titanium; Ultraviolet Rays; Water Pollutants, Chemical; Water Purification; Zinc Oxide | 2015 |
Severe meningoencephalitis co-infection due to Cryptococcus neoformans and Mycobacterium tuberculosis in a child with systemic lupus erythematosus.
Topics: Amphotericin B; Antitubercular Agents; Child; Coinfection; Cryptococcosis; Cryptococcus neoformans; Ethambutol; Female; Humans; Immunocompromised Host; Isoniazid; Lupus Erythematosus, Systemic; Meningoencephalitis; Mycobacterium tuberculosis; Pyrazinamide; Rifampin | 2015 |
Treatment options and outcomes of hospitalised tuberculosis patients: a nationwide study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antitubercular Agents; Child; Child, Preschool; Ethambutol; Female; Hospital Mortality; Hospitalization; Humans; Infant; Infant, Newborn; Isoniazid; Japan; Logistic Models; Male; Middle Aged; Multivariate Analysis; Patient Discharge; Pyrazinamide; Retrospective Studies; Rifampin; Risk Factors; Sputum; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Young Adult | 2015 |
Diseases at the crossroads: chronic myelogenous leukemia and tuberculosis.
Topics: Adult; Antitubercular Agents; Dasatinib; Ethambutol; Female; Fluoroquinolones; Humans; Isoniazid; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Moxifloxacin; Peritonitis, Tuberculous; Protein Kinase Inhibitors; Pyrazinamide; Pyrimidines; Thiazoles | 2015 |
Enhancement of in vitro activity of tuberculosis drugs by addition of thioridazine is not reflected by improved in vivo therapeutic efficacy.
Topics: Animals; Antitubercular Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Drug Therapy, Combination; Female; Isoniazid; Mice, Inbred BALB C; Microbial Sensitivity Tests; Microbial Viability; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Stem Cells; Thioridazine; Tuberculosis | 2014 |
Drug-induced hepatotoxicity of anti-tuberculosis drugs and their serum levels.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alanine Transaminase; Antitubercular Agents; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Ethambutol; Female; Humans; Isoniazid; Liver; Liver Function Tests; Male; Middle Aged; Pyrazinamide; Retrospective Studies; Rifampin; Tuberculosis, Pulmonary; Young Adult | 2015 |
Infliximab therapy in two cases of severe neurotuberculosis paradoxical reaction.
Topics: Adult; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antitubercular Agents; Dexamethasone; Ethambutol; Female; Humans; Infliximab; Isoniazid; Middle Aged; Prednisolone; Pyrazinamide; Rifampin; Tuberculoma, Intracranial; Tuberculosis, Meningeal; Tumor Necrosis Factor-alpha | 2015 |
Resolution of tubercular abscess with antitubercular treatment.
Topics: Antitubercular Agents; Brain Abscess; Child, Preschool; Drug Therapy, Combination; Humans; Isoniazid; Magnetic Resonance Imaging; Male; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Tuberculosis, Central Nervous System | 2014 |
Six- vs. eight-month anti-tuberculosis regimen for pulmonary tuberculosis under programme conditions.
Topics: Adult; Antitubercular Agents; Ethambutol; Female; Follow-Up Studies; Humans; Isoniazid; Logistic Models; Male; Middle Aged; Multivariate Analysis; Nigeria; Pyrazinamide; Retrospective Studies; Rifampin; Treatment Outcome; Tuberculosis, Pulmonary; Young Adult | 2015 |
Effective anti-tuberculosis therapy correlates with plasma small RNA.
Topics: Adult; Antitubercular Agents; Biomarkers; Coinfection; Ethambutol; Female; Gene Expression Profiling; HIV Infections; Humans; Isoniazid; Male; MicroRNAs; Prospective Studies; Pyrazinamide; Rifampin; RNA; Treatment Outcome; Tuberculosis, Pulmonary | 2015 |
[A case of tuberculous meningitis complicated with multiple drug hypersensitivity to antituberculosis agents].
Topics: Antitubercular Agents; Drug Hypersensitivity; Drug Therapy, Combination; Ethambutol; Ethionamide; Humans; Immunologic Tests; Isoniazid; Levofloxacin; Lymphocyte Activation; Male; Middle Aged; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Meningeal | 2015 |
Pharmacokinetics of anti-TB drugs in Malawian children: reconsidering the role of ethambutol.
Topics: Adolescent; Antitubercular Agents; Child; Child, Preschool; Ethambutol; Female; Humans; Infant; Isoniazid; Malawi; Male; Plasma; Pyrazinamide; Rifampin | 2015 |
[The interest of addiction to first line anti-TB drugs].
Topics: Antitubercular Agents; Drug Eruptions; Drug Hypersensitivity; Ethambutol; Female; Humans; Isoniazid; Middle Aged; Pyrazinamide | 2014 |
Safe and effective treatment for patients with isoniazid drug resistance.
Topics: Antitubercular Agents; Drug Resistance, Bacterial; Ethambutol; Female; Humans; Isoniazid; Male; Pyrazinamide; Rifampin; Tuberculosis | 2015 |
In reply.
Topics: Antitubercular Agents; Drug Resistance, Bacterial; Ethambutol; Female; Humans; Isoniazid; Male; Pyrazinamide; Rifampin; Tuberculosis | 2015 |
High effectiveness of a 12-month regimen for MDR-TB patients in Cameroon.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Cameroon; Clofazimine; Cohort Studies; Confidence Intervals; Developing Countries; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Ethambutol; Female; Fluoroquinolones; Gatifloxacin; Humans; Isoniazid; Kanamycin; Male; Medication Adherence; Middle Aged; Odds Ratio; Prospective Studies; Prothionamide; Pyrazinamide; Risk Assessment; Time Factors; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Young Adult | 2015 |
Effectiveness of RHZE-FDC (fixed-dose combination) compared to RH-FDC + Z for tuberculosis treatment in Brazil: a cohort study.
Topics: Adult; Aged; Aged, 80 and over; Antitubercular Agents; Brazil; Cohort Studies; Drug Combinations; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Pulmonary | 2015 |
An interlaboratory quality control programme for the measurement of tuberculosis drugs.
Topics: Antitubercular Agents; Drug Administration Schedule; Drug Monitoring; Humans; Immunoassay; Isoniazid; Laboratories; Pyrazinamide; Quality Control; Reference Standards; Reproducibility of Results; Rifampin; Tuberculosis | 2015 |
Pharmacokinetics of isoniazid, rifampicin, pyrazinamide and ethambutol in Indian children.
Topics: Adolescent; Antitubercular Agents; Area Under Curve; Child; Child, Preschool; Ethambutol; Ethnicity; Female; Humans; India; Infant; Isoniazid; Male; Prospective Studies; Pyrazinamide; Regression Analysis; Rifampin; Tandem Mass Spectrometry; Treatment Outcome; Tuberculosis, Pulmonary | 2015 |
High mortality associated with retreatment of tuberculosis in a clinic in Kampala, Uganda: a retrospective study.
Topics: Adult; Antitubercular Agents; Coinfection; Ethambutol; Female; Follow-Up Studies; HIV Infections; Humans; Isoniazid; Male; Middle Aged; Proportional Hazards Models; Pyrazinamide; Recurrence; Retreatment; Retrospective Studies; Rifampin; Streptomycin; Survival Rate; Treatment Failure; Treatment Outcome; Tuberculosis; Uganda | 2015 |
A Rare Cause of Retropharyngeal Abscess: Cervical Pott's Disease.
Topics: Antitubercular Agents; Biopsy, Fine-Needle; Cervical Vertebrae; Child; Diagnosis, Differential; Drug Combinations; Humans; Isoniazid; Magnetic Resonance Imaging; Male; Neck; Pyrazinamide; Radiography; Retropharyngeal Abscess; Rifampin; Treatment Outcome; Tuberculosis, Spinal | 2015 |
Coencapsulation of hydrophobic and hydrophilic antituberculosis drugs in synergistic Brij 96 microemulsions: a biophysical characterization.
Topics: Animals; Antitubercular Agents; Cell Line; Chemistry, Pharmaceutical; Chlorocebus aethiops; Emulsions; Hydrophobic and Hydrophilic Interactions; Isoniazid; Oxazines; Plant Oils; Polyethylene Glycols; Pyrazinamide; Rifampin; Solubility; Vero Cells; Xanthenes | 2015 |
Is Europe ready to reach tuberculosis elimination? An outbreak report from Southern Italy.
Topics: Adult; Child, Preschool; Communicable Disease Control; Contact Tracing; Disease Outbreaks; Ethambutol; Europe; Female; Humans; Incidence; Interferon-gamma Release Tests; Isoniazid; Italy; Male; Pyrazinamide; Rifampin; Tomography, X-Ray Computed; Tuberculosis | 2015 |
Advanced stage of chronic kidney disease is risk of poor treatment outcome for smear-positive pulmonary tuberculosis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antitubercular Agents; Cardiovascular Diseases; Child; Drug Therapy, Combination; Ethambutol; Female; Glomerular Filtration Rate; Humans; Isoniazid; Japan; Male; Middle Aged; Pyrazinamide; Renal Insufficiency, Chronic; Retrospective Studies; Rifampin; Risk Factors; Serum Albumin; Sputum; Steroids; Streptomycin; Survival Rate; Treatment Outcome; Tuberculosis, Pulmonary; Young Adult | 2015 |
Evaluation of a novel line-probe assay for genotyping-based diagnosis of Mycobacterium tuberculosis in Thailand.
Topics: Antibiotics, Antitubercular; Extensively Drug-Resistant Tuberculosis; Fluoroquinolones; Genotype; Humans; Isoniazid; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Pyrazinamide; Reagent Kits, Diagnostic; Rifampin; Sensitivity and Specificity; Sputum; Thailand | 2015 |
Pyridoxine induced rosacea-like dermatitis.
Topics: Antitubercular Agents; Drug Combinations; Drug Eruptions; Female; Humans; Isoniazid; Middle Aged; Pyrazinamide; Pyridoxine; Rifampin; Rosacea; Tuberculosis, Pulmonary; Vitamin B Complex | 2015 |
IL-37 Expression is Upregulated in Patients with Tuberculosis and Induces Macrophages Towards an M2-like Phenotype.
Topics: Antitubercular Agents; Arginase; B7-2 Antigen; Cell Differentiation; Cells, Cultured; Ethambutol; Female; Humans; Interferon-gamma; Interleukin-1; Interleukin-10; Interleukin-12 Subunit p35; Isoniazid; Lectins, C-Type; Macrophages; Male; Mannose Receptor; Mannose-Binding Lectins; Middle Aged; Mycobacterium tuberculosis; Nitric Oxide; Phagocytosis; Phenotype; Pyrazinamide; Receptors, Cell Surface; Rifampin; RNA Interference; RNA, Messenger; RNA, Small Interfering; Transcriptional Activation; Transforming Growth Factor beta; Tuberculosis, Pulmonary; Up-Regulation | 2015 |
Isolated hepatosplenic tuberculosis: a rare presentation.
Topics: Abdominal Pain; Antitubercular Agents; Diagnosis, Differential; Ethambutol; Female; Humans; Isoniazid; Middle Aged; Pyrazinamide; Rifampin; Tomography, X-Ray Computed; Treatment Outcome; Tuberculosis, Hepatic; Tuberculosis, Splenic; Weight Loss | 2015 |
A Clinical Study of Miliary Brain Tuberculomas in China.
Topics: Adult; Aged; Antitubercular Agents; Brain; Contrast Media; Drug Therapy, Combination; Ethambutol; Female; Gadolinium; Humans; Isoniazid; Magnetic Resonance Imaging; Male; Methylprednisolone; Middle Aged; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculoma, Intracranial | 2016 |
Therapeutic drug monitoring and the conservative management of chronic tuberculous empyema: case report and review of the literature.
Topics: Aged, 80 and over; Antitubercular Agents; Bronchial Fistula; Canada; Croatia; Diagnosis, Differential; Drainage; Drug Monitoring; Drug Therapy, Combination; Emigrants and Immigrants; Empyema, Tuberculous; Ethambutol; Humans; Isoniazid; Male; Pleural Diseases; Pyrazinamide; Radiography | 2015 |
Isolated tuberculosis of tunica albuginea and tunica vaginalis presenting as acute hydrocoele: a diagnostic dilemma.
Topics: Adult; Antitubercular Agents; Ethambutol; Humans; Isoniazid; Male; Pyrazinamide; Rifampin; Scrotum; Testicular Hydrocele; Testis; Treatment Outcome; Tuberculosis, Male Genital | 2015 |
The relationship between chitotriosidase activity and tuberculosis.
Topics: Adult; Aged; Aged, 80 and over; Antitubercular Agents; Biomarkers; Case-Control Studies; China; Ethambutol; Female; Hexosaminidases; Humans; Isoniazid; Lung; Male; Middle Aged; Pyrazinamide; Radiography; Rifampin; Streptomycin; Thioacetazone; Treatment Outcome; Tuberculosis, Pulmonary; Young Adult | 2015 |
Pleural tuberculosis in a patient with untreated type 1 Gaucher disease.
Topics: Adult; Antitubercular Agents; Drug Therapy, Combination; Ethambutol; Gaucher Disease; Humans; Isoniazid; Male; Pulmonary Fibrosis; Pyrazinamide; Rifampin; Tuberculosis, Pleural; Turkey | 2016 |
Serum Levels of Antituberculosis Drugs and Their Effect on Tuberculosis Treatment Outcome.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antitubercular Agents; Chromatography, Liquid; Drug Monitoring; Ethambutol; Female; Humans; Isoniazid; Male; Mass Spectrometry; Middle Aged; Multivariate Analysis; Mycobacterium tuberculosis; Pyrazinamide; Recurrence; Retrospective Studies; Rifampin; Treatment Outcome; Tuberculosis, Pulmonary | 2016 |
[The effect of renal replacement therapy on the plasma concentration of antituberculosis drugs].
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Female; Humans; Isoniazid; Kidney Diseases; Male; Middle Aged; Pyrazinamide; Renal Replacement Therapy; Rifampin; Tuberculosis; Tuberculosis, Pulmonary; Young Adult | 2015 |
Primary Gingival Tuberculosis Diagnosed Based on Genetic Identification.
Topics: Aged; Antitubercular Agents; Biopsy; Diagnosis, Differential; DNA, Bacterial; Ethambutol; Female; Gingival Diseases; Humans; Isoniazid; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Oral | 2015 |
The background and rationale for a new fixed-dose combination for first-line treatment of tuberculosis in children.
Topics: Antitubercular Agents; Body Weight; Child; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Practice Guidelines as Topic; Pyrazinamide; Rifampin; Tuberculosis; World Health Organization | 2015 |
Thanks to Trauma: A Delayed Diagnosis of Pott Disease.
Topics: Accidental Falls; Antitubercular Agents; Child, Preschool; Delayed Diagnosis; Diagnosis, Differential; Drug Therapy, Combination; Ethambutol; Fractures, Comminuted; Humans; Isoniazid; Male; Pyrazinamide; Rifampin; Spinal Injuries; Tomography, X-Ray Computed; Tuberculin Test; Tuberculosis, Spinal | 2015 |
Sterilizing Activity of Pyrazinamide in Combination with First-Line Drugs in a C3HeB/FeJ Mouse Model of Tuberculosis.
Topics: Animals; Antitubercular Agents; Disease Models, Animal; Drug Resistance, Bacterial; Drug Therapy, Combination; Ethambutol; Female; Isoniazid; Mice, Inbred BALB C; Mice, Inbred C3H; Mutation; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Pulmonary | 2016 |
Cure of tuberculosis despite serum concentrations of antituberculosis drugs below published reference ranges.
Topics: Adult; Aged; Antitubercular Agents; Drug Monitoring; Female; HIV Infections; Humans; Isoniazid; Linear Models; Male; Middle Aged; Pyrazinamide; Reference Values; Retrospective Studies; Rifampin; Switzerland; Tuberculosis; Young Adult | 2015 |
Painful Red Eye in a Woman in Her 70s.
Topics: Aged; Antitubercular Agents; Choroid Diseases; Drug Therapy, Combination; Ethambutol; Eye Infections, Bacterial; Eye Pain; Female; Humans; Interferon-gamma Release Tests; Isoniazid; Mycobacterium tuberculosis; Pyrazinamide; Radiography, Thoracic; Rifampin; Scleritis; Skin Tests; Tuberculoma; Tuberculosis, Ocular | 2016 |
Repeat exposure to active tuberculosis and risk of re-infection.
Topics: Adult; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Emergency Service, Hospital; Ethambutol; Female; Humans; Isoniazid; Mycobacterium tuberculosis; Parents; Pyrazinamide; Recurrence; Rifampin; Risk Assessment; Risk Factors; Siblings; Sputum; Time Factors; Treatment Outcome; Tuberculosis, Pulmonary | 2016 |
[CLINICAL EFFECTS OF TREATMENT FOR MYCOBACTERIUM TUBERCULOSIS INFECTION IN PATIENTS AT A SPECIALIZED HOSPITAL IN 2011].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antitubercular Agents; Child; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Ethambutol; Female; Hospitals, Special; Humans; Isoniazid; Male; Middle Aged; Mycobacterium tuberculosis; Pyrazinamide; Retrospective Studies; Rifampin; Streptomycin; Time Factors; Treatment Outcome; Tuberculosis; Young Adult | 2015 |
Low Serum Concentrations of Rifampicin and Pyrazinamide Associated with Poor Treatment Outcomes in Children with Tuberculosis Related to HIV Status.
Topics: Antitubercular Agents; Child; Child, Preschool; Chromatography, High Pressure Liquid; Female; Follow-Up Studies; HIV Infections; Hospitals; Humans; India; Infant; Isoniazid; Male; Pyrazinamide; Rifampin; Serum; Treatment Outcome; Tuberculosis | 2016 |
Global Urine Metabolomics in Patients Treated with First-Line Tuberculosis Drugs and Identification of a Novel Metabolite of Ethambutol.
Topics: Adult; Aged; Aged, 80 and over; Aminobutyrates; Antitubercular Agents; Biotransformation; Case-Control Studies; Chromatography, Gas; Ethambutol; Female; Humans; India; Isoniazid; Male; Metabolomics; Middle Aged; Mycobacterium tuberculosis; Pyrazinamide; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tuberculosis, Pulmonary | 2016 |
Later emergence of acquired drug resistance and its effect on treatment outcome in patients treated with Standard Short-Course Chemotherapy for tuberculosis.
Topics: Adolescent; Adult; Antitubercular Agents; China; Cohort Studies; Drug Resistance, Bacterial; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Mycobacterium tuberculosis; Prospective Studies; Pyrazinamide; Rifampin; Streptomycin; Treatment Failure; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Young Adult | 2016 |
Clofazimine Contributes Sustained Antimicrobial Activity after Treatment Cessation in a Mouse Model of Tuberculosis Chemotherapy.
Topics: Animals; Antitubercular Agents; Clofazimine; Disease Models, Animal; Drug Combinations; Drug Therapy, Combination; Ethambutol; Female; Isoniazid; Mice; Mice, Inbred BALB C; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Tuberculosis; Withholding Treatment | 2016 |
Rapid colorimetric pyrazinamide susceptibility testing of Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Colorimetry; Drug Resistance, Bacterial; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Sensitivity and Specificity; Tetrazolium Salts | 2016 |
Leukapheresis in the management of drug rash with eosinophilia and systemic symptoms syndrome.
Topics: Antitubercular Agents; Combined Modality Therapy; Drug Combinations; Drug Hypersensitivity Syndrome; Ethambutol; Glucocorticoids; Herpesvirus 6, Human; Humans; Isoniazid; Leukapheresis; Male; Multiple Organ Failure; Plasmapheresis; Pyrazinamide; Rifampin; Roseolovirus Infections; Tuberculosis, Pleural; Young Adult | 2017 |
Naïve-pooled pharmacokinetic analysis of pyrazinamide, isoniazid and rifampicin in plasma and cerebrospinal fluid of Vietnamese children with tuberculous meningitis.
Topics: Adolescent; Antitubercular Agents; Arylamine N-Acetyltransferase; Asian People; Child; Child, Preschool; Female; Genotype; Half-Life; Humans; Infant; Isoniazid; Male; Prospective Studies; Pyrazinamide; Rifampin; Tuberculosis, Meningeal; Vietnam | 2016 |
The clinical outcomes of oldest old patients with tuberculosis treated by regimens containing rifampicin, isoniazid, and pyrazinamide.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Comorbidity; Drug Therapy, Combination; Female; Hepatitis; Hospitals, Teaching; Humans; Isoniazid; Male; Middle Aged; Multivariate Analysis; Pyrazinamide; Retrospective Studies; Rifampin; Risk Factors; Taiwan; Treatment Outcome; Tuberculosis; Young Adult | 2016 |
Ameliorative Effects of Kolaviron, a Biflavonoid Fraction from Garcinia Kola Seed, on Hepato-renal Toxicity of Anti-tuberculosis Drugs in Wistar Rats.
Topics: Alanine Transaminase; Animals; Antioxidants; Antitubercular Agents; Aspartate Aminotransferases; Ethambutol; Flavonoids; Garcinia kola; Glutathione; Glutathione Peroxidase; Isoniazid; Kidney; Liver; Male; Malondialdehyde; Oxidative Stress; Pyrazinamide; Rats, Wistar; Rifampin; Seeds | 2016 |
Pharmacokinetics of isoniazid, rifampicin, pyrazinamide and ethambutol in HIV-infected Indian children.
Topics: Adolescent; Age Factors; Antitubercular Agents; Child; Child, Preschool; Chromatography, Liquid; Coinfection; Drug Dosage Calculations; Drug Monitoring; Ethambutol; Female; HIV Infections; Humans; India; Infant; Isoniazid; Male; Prospective Studies; Pyrazinamide; Rifampin; Spectrometry, Mass, Electrospray Ionization; Treatment Outcome; Tuberculosis | 2016 |
The outcomes of chemotherapy only treatment on mild spinal tuberculosis.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Drug Administration Schedule; Drug Therapy, Combination; Ethambutol; Female; Follow-Up Studies; Humans; Isoniazid; Kyphosis; Male; Middle Aged; Pyrazinamide; Treatment Outcome; Tuberculosis, Spinal; Young Adult | 2016 |
The effect of growth rate on pyrazinamide activity in Mycobacterium tuberculosis - insights for early bactericidal activity?
Topics: Antitubercular Agents; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Isoniazid; Mycobacterium tuberculosis; Pyrazinamide; Ribosomal Proteins; RNA, Transfer | 2016 |
Investigation of Elimination Rate, Persistent Subpopulation Removal, and Relapse Rates of Mycobacterium tuberculosis by Using Combinations of First-Line Drugs in a Modified Cornell Mouse Model.
Topics: Animals; Antitubercular Agents; Disease Models, Animal; Drug Combinations; Female; Isoniazid; Mice; Mice, Inbred BALB C; Mycobacterium tuberculosis; Pyrazinamide; Recurrence; Rifampin; Tuberculosis, Pulmonary | 2016 |
Anterior debridement may not be necessary in the treatment of tuberculous spondylitis of the thoracic and lumbar spine in adults: a retrospective study.
Topics: Adult; Aged; Aged, 80 and over; Antitubercular Agents; Decompression, Surgical; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Kyphosis; Laminectomy; Lumbar Vertebrae; Middle Aged; Pyrazinamide; Retrospective Studies; Rifampin; Spinal Fusion; Spondylitis; Thoracic Vertebrae; Tuberculosis, Spinal | 2016 |
Deleterious effects of 28-day oral co-administration of first-line anti-TB drugs on spleen, blood and bone marrow chromosomes in normal rat.
Topics: Administration, Oral; Animals; Antitubercular Agents; Biomarkers; Bone Marrow Cells; Chromosome Aberrations; DNA Damage; Drug Administration Schedule; Drug Therapy, Combination; Female; Glutathione; Isoniazid; Lipid Peroxidation; Mutagenicity Tests; Pyrazinamide; Rats, Wistar; Rifampin; Risk Assessment; Spleen; Thiobarbituric Acid Reactive Substances; Time Factors | 2017 |
Adverse effects of anti-tuberculosis drugs on HepG2 cell bioenergetics.
Topics: Adenosine Triphosphate; Antitubercular Agents; Drug Interactions; Electron Transport Complex I; Electron Transport Complex III; Energy Metabolism; Hep G2 Cells; Humans; Isoniazid; Lactic Acid; Membrane Potential, Mitochondrial; NAD; Pyrazinamide; Rifampin | 2017 |
Population pharmacokinetics, optimised design and sample size determination for rifampicin, isoniazid, ethambutol and pyrazinamide in the mouse.
Topics: Animals; Antibiotics, Antitubercular; Disease Models, Animal; Ethambutol; Isoniazid; Mice, Inbred C57BL; Models, Biological; Pyrazinamide; Rifampin; Sample Size | 2016 |
HIV-1 Coinfection Does Not Reduce Exposure to Rifampin, Isoniazid, and Pyrazinamide in South African Tuberculosis Outpatients.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Antitubercular Agents; Area Under Curve; Biological Availability; Coinfection; Female; HIV Infections; HIV-1; Humans; Isoniazid; Lopinavir; Male; Models, Statistical; Mycobacterium tuberculosis; Outpatients; Prospective Studies; Pyrazinamide; Rifampin; Ritonavir; South Africa; Tuberculosis, Pulmonary | 2016 |
Bacterial Loads Measured by the Xpert MTB/RIF Assay as Markers of Culture Conversion and Bacteriological Cure in Pulmonary TB.
Topics: Antitubercular Agents; Area Under Curve; Bacterial Load; Bacteriological Techniques; Biomarkers; Ethambutol; Female; Humans; Isoniazid; Male; Mycobacterium tuberculosis; Pyrazinamide; ROC Curve; Sensitivity and Specificity; Treatment Failure; Tuberculosis, Pulmonary | 2016 |
Pharmacokinetics of thrice-weekly rifampicin, isoniazid and pyrazinamide in adult tuberculosis patients in India.
Topics: Adult; Antitubercular Agents; Arylamine N-Acetyltransferase; Female; Genotyping Techniques; Humans; India; Isoniazid; Male; Middle Aged; Prospective Studies; Pyrazinamide; Rifampin; Sample Size; Tuberculosis; Young Adult | 2016 |
[EVALUATION OF THE EFFICIENCY OF TREATMENT AND THE CHOICE OF CONTROL COMPUTED TOMOGRAPHY TIME IN CHILDREN WITH MINOR FORMS OF INTRATHORACIC TUBERCULOSIS].
Topics: Antitubercular Agents; Child; Child, Preschool; Comparative Effectiveness Research; Drug Monitoring; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Lymph Nodes; Male; Outcome Assessment, Health Care; Pyrazinamide; Rifampin; Thorax; Tomography, X-Ray Computed; Tuberculosis, Lymph Node; Tuberculosis, Pulmonary | 2010 |
Simultaneous quantification of isoniazid, rifampicin, ethambutol and pyrazinamide by liquid chromatography/tandem mass spectrometry.
Topics: Antitubercular Agents; Chromatography, Liquid; Drug Monitoring; Ethambutol; Humans; Isoniazid; Plasma; Pyrazinamide; Rifampin; Tandem Mass Spectrometry | 2016 |
Cutaneous Tuberculosis Occurring After a Skin Cut in a Child.
Topics: Abattoirs; Adolescent; Animals; Antitubercular Agents; Axilla; Ethambutol; Finger Injuries; Humans; Isoniazid; Lupus Vulgaris; Lymphadenopathy; Male; Mycobacterium tuberculosis; Occupational Diseases; Pyrazinamide; Rifampin; Sheep; Treatment Outcome; Turkey; Wound Healing | 2016 |
Fixed-dose combination and therapeutic drug monitoring in tuberculosis: friend or foe?
Topics: Antitubercular Agents; Drug Combinations; Drug Monitoring; Humans; Isoniazid; Pyrazinamide; Rifampin; Tuberculosis | 2016 |
Interactions of linezolid and second-line anti-tuberculosis agents against multidrug-resistant Mycobacterium tuberculosis in vitro and in vivo.
Topics: Aminosalicylic Acid; Animals; Antitubercular Agents; Capreomycin; Drug Combinations; Drug Interactions; Humans; Isoniazid; Linezolid; Male; Mice, Inbred BALB C; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Tuberculosis, Multidrug-Resistant | 2016 |
Comprehensive cost of treating one patient with MDR/pre-XDR-TB in Wellington, New Zealand.
Topics: Adult; Amikacin; Aminosalicylic Acid; Anti-Bacterial Agents; Antitubercular Agents; Bronchoscopy; Clofazimine; Depression; Drug Costs; Emigrants and Immigrants; Ethambutol; Extensively Drug-Resistant Tuberculosis; Fluoroquinolones; Health Care Costs; Humans; India; Isoniazid; Linezolid; Male; Mediastinum; Microbial Sensitivity Tests; Moxifloxacin; New Zealand; Pyrazinamide; Radiography, Thoracic; Rifampin; Schizophrenia, Paranoid; Tuberculosis, Lymph Node; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pleural; Tuberculosis, Pulmonary | 2016 |
The antifibrotic drug pirfenidone promotes pulmonary cavitation and drug resistance in a mouse model of chronic tuberculosis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antitubercular Agents; Drug Resistance, Bacterial; Drug Therapy, Combination; Female; Humans; Isoniazid; Mice; Mice, Inbred C3H; Pyrazinamide; Pyridones; Rifampin; Treatment Outcome; Tuberculosis, Pulmonary | 2016 |
Association between TXNRD1 polymorphisms and anti-tuberculosis drug-induced hepatotoxicity in a prospective study.
Topics: Adult; Age Factors; Alleles; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Ethambutol; Female; Gene Expression; Gene Frequency; Haplotypes; Humans; Isoniazid; Liver; Lung; Male; Middle Aged; Mycobacterium tuberculosis; Polymorphism, Single Nucleotide; Prospective Studies; Pyrazinamide; Rifampin; Risk Factors; Sex Factors; Thioredoxin Reductase 1; Tuberculosis, Pulmonary | 2016 |
Mechanisms of first-line antimicrobial resistance in multi-drug and extensively drug resistant strains of Mycobacterium tuberculosis in KwaZulu-Natal, South Africa.
Topics: Amidohydrolases; Antitubercular Agents; Bacterial Proteins; Catalase; Drug Resistance, Multiple, Bacterial; Ethambutol; Extensively Drug-Resistant Tuberculosis; Humans; Isoniazid; Mutation; Mycobacterium tuberculosis; Oxidoreductases; Pentosyltransferases; Polymorphism, Restriction Fragment Length; Pyrazinamide; Rifampin; South Africa; Tuberculosis, Multidrug-Resistant | 2016 |
Role of Risorine in the Treatment of Drug - Susceptible Pulmonary Tuberculosis: A Pilot Study.
Topics: Adult; Alkaloids; Antitubercular Agents; Benzodioxoles; Cytochrome P-450 Enzyme Inhibitors; Drug Combinations; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Pilot Projects; Piperidines; Polyunsaturated Alkamides; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary; Young Adult | 2016 |
Applicability of the shorter 'Bangladesh regimen' in high multidrug-resistant tuberculosis settings.
Topics: Antitubercular Agents; Clinical Protocols; Diarylquinolines; Drug Therapy, Combination; Ethambutol; Fluoroquinolones; Humans; Isoniazid; Moxifloxacin; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Pyrazinamide; Tuberculosis, Multidrug-Resistant; World Health Organization | 2017 |
Drug-related hepatitis in patients treated with standard anti-tuberculosis chemotherapy over a 30-year period.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Ethambutol; Female; Follow-Up Studies; Hepatitis; Humans; Incidence; Infant; Infant, Newborn; Isoniazid; Longitudinal Studies; Male; Middle Aged; Prospective Studies; Pyrazinamide; Rifampin; Tuberculosis; Young Adult | 2016 |
Resistance to First-Line Antituberculosis Drugs in Washington State by Region of Birth and Implications for Latent Tuberculosis Treatment Among Foreign-Born Individuals.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antitubercular Agents; Child; Child, Preschool; Drug Resistance, Bacterial; Ethambutol; Female; Humans; Infant; Infant, Newborn; Isoniazid; Latent Tuberculosis; Logistic Models; Male; Mexico; Middle Aged; Multivariate Analysis; Philippines; Pyrazinamide; Rifampin; Risk Factors; Vietnam; Washington; Young Adult | 2017 |
Tuberculous Meningitis in an Immunocompetent Host: A Case Report.
Topics: Antitubercular Agents; Cerebrospinal Fluid; Drug Therapy, Combination; Emigrants and Immigrants; Humans; Immunocompetence; Isoniazid; Levofloxacin; Male; Middle Aged; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Senegal; Treatment Outcome; Tuberculosis, Meningeal; United States | 2016 |
Drug-drug cocrystals of antituberculous 4-aminosalicylic acid: Screening, crystal structures, thermochemical and solubility studies.
Topics: Aminosalicylic Acid; Antitubercular Agents; Caffeine; Crystallization; Crystallography, X-Ray; Drug Stability; Isoniazid; Models, Molecular; Niacinamide; Powder Diffraction; Pyrazinamide; Solubility; Theophylline; X-Ray Diffraction | 2017 |
Tuberculous pericarditis: a case report.
Topics: Aged; Antitubercular Agents; Ethambutol; Humans; Isoniazid; Male; Pericarditis, Tuberculous; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculin Test | 2016 |
Treatment outcomes of fixed-dose combination versus separate tablet regimens in pulmonary tuberculosis patients with or without diabetes in Qatar.
Topics: Adult; Antitubercular Agents; Diabetes Complications; Dose-Response Relationship, Drug; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Ethambutol; Female; Hospitals, General; Humans; Isoniazid; Male; Pyrazinamide; Qatar; Retrospective Studies; Rifampin; Sputum; Tablets; Treatment Outcome; Tuberculosis, Pulmonary | 2017 |
Concentration-Dependent Antagonism and Culture Conversion in Pulmonary Tuberculosis.
Topics: Adult; Antitubercular Agents; Coinfection; Drug Interactions; Drug Therapy, Combination; Female; HIV Infections; Humans; Isoniazid; Logistic Models; Male; Microbial Sensitivity Tests; Middle Aged; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Sputum; Treatment Outcome; Tuberculosis, Pulmonary | 2017 |
TB Alliance regimen development for multidrug-resistant tuberculosis.
Topics: Antitubercular Agents; Clinical Protocols; Diarylquinolines; Dose-Response Relationship, Drug; Ethambutol; Extensively Drug-Resistant Tuberculosis; Fluoroquinolones; Humans; Isoniazid; Linezolid; Moxifloxacin; Nitroimidazoles; Pyrazinamide; Randomized Controlled Trials as Topic; Research Design; Rifampin; Tuberculosis, Multidrug-Resistant | 2016 |
Factors Influencing Tuberculosis Treatment Outcome in Adult Patients Treated with Thrice-Weekly Regimens in India.
Topics: Adult; Antitubercular Agents; Arylamine N-Acetyltransferase; Drug Dosage Calculations; Drug Therapy, Combination; Female; Humans; India; Isoniazid; Male; Middle Aged; Prospective Studies; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Pulmonary | 2017 |
First line anti-tuberculosis induced hepatotoxicity: incidence and risk factors.
Topics: Adult; Aged; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Drug Monitoring; Female; Humans; Incidence; Isoniazid; Logistic Models; Male; Middle Aged; Morocco; Pyrazinamide; Retrospective Studies; Rifampin; Risk Factors; Tuberculosis | 2016 |
Concomitant metastatic cutaneous tuberculous abscesses and Pott disease in an immunocompetent patient.
Topics: Abscess; Adult; Antitubercular Agents; Arthrodesis; Debridement; Ethambutol; Humans; Immunocompetence; Isoniazid; Magnetic Resonance Imaging; Male; Pyrazinamide; Rifampin; Tuberculosis, Cutaneous; Tuberculosis, Spinal | 2016 |
Association of CYP2B6 gene polymorphisms and anti-tuberculosis drug-induced hepatotoxicity in a Chinese population.
Topics: Adult; Alleles; Antitubercular Agents; Asian People; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2B6; Ethambutol; Female; Gene Expression; Gene Frequency; Genetic Predisposition to Disease; Haplotypes; Humans; Isoniazid; Male; Middle Aged; Mycobacterium tuberculosis; Polymorphism, Single Nucleotide; Prospective Studies; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 2017 |
The Rate of Drug-Resistant Tuberculosis in Korean Children and Adolescents Since 2007.
Topics: Adolescent; Antitubercular Agents; Asian People; Child; Child, Preschool; Drug Resistance, Multiple, Bacterial; Ethambutol; Female; Humans; Incidence; Infant; Isoniazid; Male; Mycobacterium tuberculosis; Pyrazinamide; Republic of Korea; Rifampin; Tuberculosis, Multidrug-Resistant; Young Adult | 2017 |
Chloroquine enhances the antimycobacterial activity of isoniazid and pyrazinamide by reversing inflammation-induced macrophage efflux.
Topics: Antitubercular Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; Chloroquine; Drug Synergism; Humans; Isoniazid; Macrophages; Mycobacterium tuberculosis; Neoplasm Proteins; Pyrazinamide; THP-1 Cells | 2017 |
Metformin Adjunctive Therapy Does Not Improve the Sterilizing Activity of the First-Line Antitubercular Regimen in Mice.
Topics: Animals; Antitubercular Agents; Bacterial Load; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Female; Isoniazid; Lung; Metformin; Mice; Mice, Inbred BALB C; Mycobacterium tuberculosis; Pyrazinamide; Recurrence; Rifampin; Tuberculosis, Pulmonary | 2017 |
Poncet's disease in human immunodeficiency virus: a case report.
Topics: Adult; Antibiotics, Antitubercular; Antiretroviral Therapy, Highly Active; Arthritis, Reactive; Ethambutol; HIV Infections; Humans; Isoniazid; Male; Pyrazinamide; Rifampin; Tomography, X-Ray Computed; Tuberculosis, Pulmonary | 2017 |
Pharmacokinetics of Pyrazinamide and Optimal Dosing Regimens for Drug-Sensitive and -Resistant Tuberculosis.
Topics: Adolescent; Adult; Antitubercular Agents; Coinfection; Drug Combinations; Ethambutol; HIV Infections; Humans; Isoniazid; Male; Metabolic Clearance Rate; Middle Aged; Pyrazinamide; Rifampin; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Young Adult | 2017 |
Assessment of treatment response by colony forming units, time to culture positivity and the molecular bacterial load assay compared in a mouse tuberculosis model.
Topics: Animals; Antitubercular Agents; Bacterial Load; Colony Count, Microbial; Disease Models, Animal; DNA, Bacterial; Ethambutol; Female; Isoniazid; Lung; Mice, Inbred BALB C; Mycobacterium tuberculosis; Nonlinear Dynamics; Predictive Value of Tests; Pyrazinamide; Ribotyping; Rifampin; RNA, Ribosomal, 16S; Streptomycin; Time Factors; Tuberculosis, Pulmonary | 2017 |
Inhibitory Effects of Selected Antituberculosis Drugs on Common Human Hepatic Cytochrome P450 and UDP-glucuronosyltransferase Enzymes.
Topics: Acetaminophen; Antitubercular Agents; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Diarylquinolines; Enzyme Inhibitors; Ethambutol; Glucuronosyltransferase; Humans; Inhibitory Concentration 50; Isoenzymes; Isoniazid; Kinetics; Liver; Pyrazinamide; Rifabutin | 2017 |
Longitudinal profiling reveals a persistent intestinal dysbiosis triggered by conventional anti-tuberculosis therapy.
Topics: Animals; Antitubercular Agents; Clostridiales; Drug Combinations; Dysbiosis; Gastrointestinal Microbiome; Intestines; Isoniazid; Mice; Mycobacterium tuberculosis; Porphyromonas; Pyrazinamide; Rifampin; RNA, Ribosomal, 16S; Tuberculosis, Pulmonary | 2017 |
Massive choroidal granuloma as the presenting feature of disseminated tuberculosis in immunocompetent patients.
Topics: Adolescent; Adult; Antitubercular Agents; Choroid Diseases; Drug Combinations; Ethambutol; Female; Granuloma; Humans; Immunocompetence; Isoniazid; Magnetic Resonance Imaging; Male; Pyrazinamide; Rifampin; Tomography, X-Ray Computed; Tuberculosis, Ocular; Tuberculosis, Pulmonary; Ultrasonography | 2018 |
Silicotuberculosis with oesophagobronchial fistulas and broncholithiasis: a case report.
Topics: Aged; Antibiotics, Antitubercular; Bronchial Fistula; Esophageal Fistula; Esophagoscopy; Female; Humans; Isoniazid; Lithiasis; Pyrazinamide; Rifampin; Silicotuberculosis; Stents; Treatment Outcome | 2018 |
Serum levels of soluble urokinase plasminogen activator receptor (suPAR) as a marker of tuberculosis treatment efficacy.
Topics: Adult; Aged; Antitubercular Agents; Biomarkers; Drug Monitoring; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Receptors, Urokinase Plasminogen Activator; Rifampin; Tuberculosis, Pulmonary; Young Adult | 2017 |
Antimicrobial activity of organometallic isonicotinyl and pyrazinyl ferrocenyl-derived complexes.
Topics: Aldehydes; Animals; Anti-Bacterial Agents; Antiparasitic Agents; CHO Cells; Coordination Complexes; Cricetulus; Ferrous Compounds; Humans; Iridium; Isoniazid; Isonicotinic Acids; Metallocenes; Mycobacterium tuberculosis; Plasmodium falciparum; Pyrazinamide; Rhodium; Ruthenium; Trichomonas vaginalis | 2017 |
Simultaneous Determination of First-Line 4-FDC Antituberculosis Drugs by UHPLC-UV and HPLC-UV: A Comparative Study.
Topics: Antitubercular Agents; Chromatography, High Pressure Liquid; Ethambutol; Isoniazid; Pyrazinamide; Rifampin | 2017 |
A 25-Year-Old Woman With a Deceptive Pancreas Cyst: All Is Not as It Appears!
Topics: Adult; Antitubercular Agents; Drug Therapy, Combination; Endoscopic Ultrasound-Guided Fine Needle Aspiration; Ethambutol; Female; Humans; Isoniazid; Mycobacterium tuberculosis; Pancreatic Cyst; Pyrazinamide; Rifampin; Tomography, X-Ray Computed; Treatment Outcome; Tuberculosis | 2018 |
Assessment of Bactericidal Drug Activity and Treatment Outcome in a Mouse Tuberculosis Model Using a Clinical Beijing Strain.
Topics: Animals; Antitubercular Agents; Disease Models, Animal; Drug Therapy, Combination; Ethambutol; Female; Isoniazid; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Streptomycin; Treatment Outcome; Tuberculosis, Pulmonary | 2017 |
Urine trouble: genitourinary tuberculosis and subsequent DRESS syndrome.
Topics: Adult; Antibiotics, Antitubercular; Drug Hypersensitivity Syndrome; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Pyrazinamide; Rifabutin; Tuberculosis, Urogenital | 2017 |
An unusual pain in the gut.
Topics: Abdominal Pain; Africa; Anti-Bacterial Agents; Colon, Transverse; Colonoscopy; Diagnosis, Differential; Ethambutol; Female; Humans; Isoniazid; Middle Aged; Mycobacterium bovis; Pyrazinamide; Rifampin; Thailand; Travel; Treatment Outcome; Tuberculosis, Gastrointestinal | 2017 |
The clinical recovery of tuberculosis patients undergoing specific treatment is associated with changes in the immune and neuroendocrine responses.
Topics: Adult; Antitubercular Agents; C-Reactive Protein; Case-Control Studies; Dehydroepiandrosterone; Ethambutol; Female; Gene Expression Regulation; Humans; Hydrocortisone; Interferon-gamma; Interleukin-6; Isoniazid; Leukocytes, Mononuclear; Male; Middle Aged; Mycobacterium tuberculosis; Pyrazinamide; Receptors, Glucocorticoid; Rifampin; Transforming Growth Factor beta; Treatment Outcome; Tuberculosis, Pulmonary | 2017 |
Food significantly reduces plasma concentrations of first-line anti-tuberculosis drugs.
Topics: Adult; Antitubercular Agents; Fasting; Female; Food; Humans; India; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Tuberculosis | 2017 |
Cohort profile of a study on outcomes related to tuberculosis and antiretroviral drug concentrations in Uganda: design, methods and patient characteristics of the SOUTH study.
Topics: Adult; Anti-Retroviral Agents; Antitubercular Agents; Biomedical Research; CD4 Lymphocyte Count; Cohort Studies; Coinfection; Drug Combinations; Ethambutol; Female; HIV Infections; Humans; Isoniazid; Male; Pyrazinamide; Research Design; Rifampin; Tuberculosis, Pulmonary; Uganda | 2017 |
Treatment outcomes of rifampin-sparing treatment in patients with pulmonary tuberculosis with rifampin-mono-resistance or rifampin adverse events: A retrospective cohort analysis.
Topics: Adult; Age Distribution; Aged; Alcohol Drinking; Aminosalicylic Acid; Antitubercular Agents; Cohort Studies; Comorbidity; Cycloserine; Ethambutol; Female; Fluoroquinolones; HIV Infections; Humans; Isoniazid; Male; Middle Aged; Prothionamide; Pyrazinamide; Republic of Korea; Retrospective Studies; Rifampin; Severity of Illness Index; Treatment Outcome; Tuberculosis; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 2017 |
Achieving High
Topics: Antitubercular Agents; Deuterium; Ethambutol; Isoniazid; Magnetic Resonance Spectroscopy; Pyrazinamide; Rifampin | 2017 |
'A most malignant malady': a rare case of laryngeal tuberculosis in epidermal growth factor receptor mutant lung adenocarcinoma.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Adult; Antibiotics, Antitubercular; Drug Therapy, Combination; Dysphonia; ErbB Receptors; Ethambutol; Female; Gene Expression Regulation, Neoplastic; Humans; Isoniazid; Lung Neoplasms; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Laryngeal | 2017 |
Prescription practice of anti-tuberculosis drugs in Yunnan, China: A clinical audit.
Topics: Adult; Aged; Antitubercular Agents; Asian People; China; Clinical Audit; Ethambutol; Female; Fluoroquinolones; Humans; Isoniazid; Male; Middle Aged; Outcome Assessment, Health Care; Prescriptions; Pyrazinamide; Retreatment; Rifampin; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 2017 |
Secretome profile analysis of multidrug-resistant, monodrug-resistant and drug-susceptible Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Drug Resistance, Multiple, Bacterial; Ethambutol; Gene Expression Profiling; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Proteomics; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Multidrug-Resistant | 2018 |
Pharmacokinetics and Drug-Drug Interactions of Lopinavir-Ritonavir Administered with First- and Second-Line Antituberculosis Drugs in HIV-Infected Children Treated for Multidrug-Resistant Tuberculosis.
Topics: Anti-HIV Agents; Antitubercular Agents; Child; Drug Administration Schedule; Drug Combinations; Drug Interactions; Ethambutol; Female; HIV; HIV Infections; Humans; Isoniazid; Lopinavir; Male; Models, Statistical; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Ritonavir; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 2018 |
Outcomes of pulmonary tuberculosis in patients with discordant phenotypic isoniazid resistance testing.
Topics: Aged; Antitubercular Agents; Drug Resistance, Bacterial; Drug Therapy, Combination; Ethambutol; Female; Fluoroquinolones; Humans; Isoniazid; Male; Middle Aged; Mycobacterium tuberculosis; Nucleic Acid Synthesis Inhibitors; Pyrazinamide; Republic of Korea; Retrospective Studies; Rifampin; Treatment Failure; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 2017 |
Tuberculosis of the tonsil simulating a cancer.
Topics: Adenoids; Adult; Antitubercular Agents; Diagnosis, Differential; Ethambutol; Female; Humans; Isoniazid; Mycobacterium tuberculosis; Pharyngeal Neoplasms; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis | 2017 |
A retrospective study on tuberculosis treatment outcomes at Jinka General Hospital, southern Ethiopia.
Topics: Adolescent; Adult; Antitubercular Agents; Coinfection; Drug Combinations; Ethambutol; Ethiopia; Female; HIV Infections; Hospitals, General; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Retrospective Studies; Rifampin; Sex Factors; Streptomycin; Survival Analysis; Treatment Outcome; Tuberculosis, Pulmonary | 2017 |
Machine learning for classifying tuberculosis drug-resistance from DNA sequencing data.
Topics: Antitubercular Agents; Ciprofloxacin; Ethambutol; Humans; Isoniazid; Machine Learning; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Rifampin; Sequence Analysis, DNA; Streptomycin; Tuberculosis, Multidrug-Resistant | 2018 |
A Painful Red Eye.
Topics: Alcoholism; Antitubercular Agents; Conjunctival Diseases; Ethambutol; Eye Pain; Glucocorticoids; Humans; Hyperemia; Interferon-gamma; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Scleritis; Tobacco Use Disorder; Tuberculosis, Pulmonary | 2018 |
Optimal doses of rifampicin in the standard drug regimen to shorten tuberculosis treatment duration and reduce relapse by eradicating persistent bacteria.
Topics: Animals; Antitubercular Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Isoniazid; Lung; Mice; Mice, Inbred BALB C; Mycobacterium tuberculosis; Pyrazinamide; Recurrence; Rifampin; Spleen; Tuberculosis | 2018 |
Suboptimal Antituberculosis Drug Concentrations and Outcomes in Small and HIV-Coinfected Children in India: Recommendations for Dose Modifications.
Topics: Adolescent; Age Factors; Antitubercular Agents; Body Weight; Child; Child, Preschool; Coinfection; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Dosage Calculations; Drug Monitoring; Drug Therapy, Combination; Female; HIV Infections; Humans; India; Infant; Isoniazid; Male; Models, Biological; Pyrazinamide; Rifampin; Time Factors; Treatment Outcome; Tuberculosis | 2018 |
Treatment outcomes and tolerability of the revised WHO anti-tuberculosis drug dosages for children.
Topics: Antitubercular Agents; Child, Preschool; Cohort Studies; Female; HIV Infections; Humans; Infant; Infant, Newborn; Isoniazid; Male; Malnutrition; Patient Compliance; Practice Guidelines as Topic; Prospective Studies; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Pulmonary; Uganda; World Health Organization | 2018 |
Drug resistant tuberculosis in Saudi Arabia: an analysis of surveillance data 2014-2015.
Topics: Adult; Age Factors; Antitubercular Agents; Ethambutol; Female; Humans; Isoniazid; Logistic Models; Male; Microbial Sensitivity Tests; Middle Aged; Mycobacterium tuberculosis; Pyrazinamide; Regression Analysis; Retrospective Studies; Rifampin; Saudi Arabia; Sex Factors; Streptomycin; Tuberculosis, Multidrug-Resistant; World Health Organization; Young Adult | 2018 |
Antituberculosis Treatment in a Patient with Celiac Disease.
Topics: Aged; Antitubercular Agents; Celiac Disease; Diarrhea; Diet, Gluten-Free; Drug Compounding; Drug Substitution; Drug Therapy, Combination; Ethambutol; Glutens; Hemoptysis; Humans; Isoniazid; Male; Metronidazole; Moxifloxacin; Pyrazinamide; Rifampin; Smoking; Tomography, X-Ray Computed; Tuberculosis, Pulmonary | 2018 |
A Woman With Confusion and Blurred Vision.
Topics: Antitubercular Agents; Brain Mapping; Choroiditis; Confusion; Female; Humans; Isoniazid; Magnetic Resonance Imaging; Meningitis; Middle Aged; Optic Nerve Diseases; Pyrazinamide; Rifampin; Tuberculosis, Central Nervous System; Vision Disorders | 2018 |
First-line anti-tuberculosis drugs induce hepatotoxicity: A novel mechanism based on a urinary metabolomics platform.
Topics: Adult; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Ethambutol; Female; Humans; Isoniazid; Liver; Male; Mass Spectrometry; Metabolic Networks and Pathways; Metabolomics; Middle Aged; Purines; Pyrazinamide; Rifampin; Tuberculosis; Young Adult | 2018 |
Improved Stability of Tuberculosis Drug Fixed-Dose Combination Using Isoniazid-Caffeic Acid and Vanillic Acid Cocrystal.
Topics: Antitubercular Agents; Caffeic Acids; Crystallization; Drug Combinations; Drug Stability; Drug Storage; Ethambutol; Humans; Isoniazid; Models, Molecular; Pyrazinamide; Rifampin; Tuberculosis; Vanillic Acid | 2018 |
Tuberculosis treatment outcome and predictors in northern Ethiopian prisons: a five-year retrospective analysis.
Topics: Adolescent; Adult; Aftercare; Anti-Retroviral Agents; Antitubercular Agents; Coinfection; Directly Observed Therapy; Drug Therapy, Combination; Ethambutol; Ethiopia; Female; HIV Infections; Humans; Isoniazid; Logistic Models; Lost to Follow-Up; Male; Multivariate Analysis; Patient Discharge; Patient Transfer; Prisoners; Prisons; Pyrazinamide; Retreatment; Retrospective Studies; Rifampin; Risk Factors; Sputum; Streptomycin; Treatment Failure; Treatment Outcome; Tuberculosis; Tuberculosis, Pulmonary; Young Adult | 2018 |
Sex differences and factors influencing the duration of the QT interval in patients on anti-tuberculosis therapy.
Topics: Antitubercular Agents; Clinical Trials as Topic; Electrocardiography; Ethambutol; Female; Gatifloxacin; Heart Rate; Humans; Isoniazid; Male; Models, Theoretical; Multivariate Analysis; Pyrazinamide; Rifampin; Sex Factors; Tuberculosis | 2018 |
Rapid and sensitive method for simultaneous determination of first-line anti-tuberculosis drugs in human plasma by HPLC-MS/MS: Application to therapeutic drug monitoring.
Topics: Antitubercular Agents; Chromatography, High Pressure Liquid; Drug Monitoring; Ethambutol; Humans; Isoniazid; Predictive Value of Tests; Pyrazinamide; Reproducibility of Results; Rifampin; Spectrometry, Mass, Electrospray Ionization; Streptomycin; Tandem Mass Spectrometry; Tuberculosis | 2018 |
Effect of Antituberculous Therapy on Uveitis Associated With Latent Tuberculosis.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Child; Child, Preschool; Drug Therapy, Combination; Ethambutol; Female; Follow-Up Studies; Glucocorticoids; Humans; Immunosuppressive Agents; Interferon-gamma Release Tests; Isoniazid; Latent Tuberculosis; Male; Middle Aged; Pyrazinamide; Recurrence; Retrospective Studies; Rifampin; Treatment Outcome; Tuberculosis, Ocular; Uveitis; Visual Acuity | 2018 |
Short Communication - Synthesis of drug metal complexes and their influence on human platelet aggregation.
Topics: Coordination Complexes; Drug Evaluation, Preclinical; Fluconazole; Humans; Isoniazid; Losartan; Metformin; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyrazinamide | 2018 |
[Management and treatment difficulties of multi-drug resistant pulmonary tuberculosis in a pediatric case].
Topics: Adult; Antitubercular Agents; Female; Humans; Infant; Isoniazid; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 2018 |
[Optochiasmatic tuberculomas as a paradoxical reaction to treatment for meningeal tuberculosis].
Topics: Adult; Antitubercular Agents; Brain Infarction; Diagnostic Errors; Disease Progression; Drug Resistance, Microbial; Drug Substitution; Ethambutol; Female; Host-Pathogen Interactions; Humans; Isoniazid; Magnetic Resonance Imaging; Meningitis, Viral; Moxifloxacin; Mycobacterium tuberculosis; Neuroimaging; Optic Chiasm; Paresis; Prednisone; Pyrazinamide; Rifampin; Thalamus; Tuberculoma; Tuberculosis, Meningeal; Vision Disorders | 2018 |
Intermediate Susceptibility Dose-Dependent Breakpoints For High-Dose Rifampin, Isoniazid, and Pyrazinamide Treatment in Multidrug-Resistant Tuberculosis Programs.
Topics: Algorithms; Antitubercular Agents; Humans; Isoniazid; Microbial Sensitivity Tests; Monte Carlo Method; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; South Africa; Tuberculosis, Multidrug-Resistant | 2018 |
Protein Binding of First-Line Antituberculosis Drugs.
Topics: Adult; Aged; Aged, 80 and over; Antitubercular Agents; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Protein Binding; Pyrazinamide; Rifampin; Tuberculosis | 2018 |
A Breast Lump in an Elderly Lady - Carcinoma or else ?.
Topics: Aged; Antitubercular Agents; Biopsy, Fine-Needle; Breast; Breast Neoplasms; Ethambutol; Female; Humans; Isoniazid; Pyrazinamide; Rifampin; Tuberculosis | 2016 |
Perianal ulcerative skin tuberculosis: A case report.
Topics: Aged; Antitubercular Agents; Ethambutol; Fissure in Ano; Humans; Isoniazid; Male; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Sputum; Tomography, X-Ray Computed; Treatment Outcome; Tuberculosis, Cutaneous; Tuberculosis, Pulmonary | 2018 |
Drug-resistance patterns of Mycobacterium tuberculosis strains and associated risk factors among multi drug-resistant tuberculosis suspected patients from Ethiopia.
Topics: Antitubercular Agents; Ethambutol; Ethiopia; Female; HIV Infections; Humans; Isoniazid; Male; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Risk Factors; Sputum; Streptomycin; Tuberculosis, Multidrug-Resistant | 2018 |
Intrapatient variability in plasma rifampicin & isoniazid in tuberculosis patients.
Topics: Adolescent; Adult; Antitubercular Agents; Humans; India; Isoniazid; Pilot Projects; Prospective Studies; Pyrazinamide; Rifampin; Tuberculosis | 2018 |
Interfacial Phenomenon Based Biocompatible Alginate-Chitosan Nanoparticles Containing Isoniazid and Pyrazinamide.
Topics: Alginates; Antitubercular Agents; Biocompatible Materials; Chitosan; Drug Carriers; Drug Liberation; Isoniazid; Nanoparticles; Particle Size; Pyrazinamide | 2018 |
Bifidobacterium adolescentis is intrinsically resistant to antitubercular drugs.
Topics: Antitubercular Agents; Bacterial Proteins; Bifidobacterium adolescentis; Binding Sites; Drug Resistance, Multiple, Bacterial; Isoniazid; Microbial Sensitivity Tests; Molecular Docking Simulation; Mutation; Protein Binding; Protein Domains; Pyrazinamide; Rifamycins; RNA Polymerase II | 2018 |
Effect of Diabetes Mellitus on the Pharmacokinetics and Pharmacodynamics of Tuberculosis Treatment.
Topics: Adult; Antitubercular Agents; Diabetes Mellitus; Female; Glycated Hemoglobin; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Sputum; Tuberculosis, Pulmonary; Young Adult | 2018 |
Characterizing the Effects of Glutathione as an Immunoadjuvant in the Treatment of Tuberculosis.
Topics: Adjuvants, Immunologic; Anti-Bacterial Agents; Antitubercular Agents; Cell Line; Drug Therapy, Combination; Ethambutol; Glutathione; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; THP-1 Cells; Tuberculosis; Tuberculosis, Multidrug-Resistant | 2018 |
Improved Treatment Outcomes With Bedaquiline When Substituted for Second-line Injectable Agents in Multidrug-resistant Tuberculosis: A Retrospective Cohort Study.
Topics: Adult; Antitubercular Agents; Coinfection; Diarylquinolines; Drug Resistance, Multiple, Bacterial; Ethambutol; Ethionamide; Female; HIV; HIV Infections; Humans; Isoniazid; Isoxazoles; Levofloxacin; Male; Mycobacterium tuberculosis; Oxazolidinones; Pyrazinamide; Retrospective Studies; South Africa; Survival Analysis; Treatment Outcome; Tuberculosis, Multidrug-Resistant | 2019 |
Optic Perineuritis Due to Tuberculosis.
Topics: Adult; Antitubercular Agents; Bronchoscopy; Drug Therapy, Combination; Humans; Isoniazid; Magnetic Resonance Imaging; Male; Optic Neuritis; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary; Vision Disorders; Visual Acuity; Visual Fields | 2019 |
Predicting the Outcomes of New Short-Course Regimens for Multidrug-Resistant Tuberculosis Using Intrahost and Pharmacokinetic-Pharmacodynamic Modeling.
Topics: Antitubercular Agents; Clofazimine; Colony Count, Microbial; Computer Simulation; Diarylquinolines; Dose-Response Relationship, Drug; Drug Dosage Calculations; Drug Resistance, Bacterial; Drug Therapy, Combination; Ethambutol; Host-Pathogen Interactions; Humans; Immunity, Innate; Isoniazid; Kanamycin; Macrophages; Microbial Sensitivity Tests; Models, Statistical; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Prothionamide; Pyrazinamide; Time Factors; Tuberculosis, Multidrug-Resistant | 2018 |
Miliary tuberculosis and herpes pharyngitis after a trip to a developing country: dangers of biologics.
Topics: Adalimumab; Aged, 80 and over; Anti-Bacterial Agents; Antirheumatic Agents; Antitubercular Agents; Arthritis, Rheumatoid; Biological Products; Developing Countries; Diagnosis, Differential; Herpes Simplex; Herpesvirus 1, Human; Humans; India; Isoniazid; Levofloxacin; Lung; Male; Opportunistic Infections; Pharyngitis; Pyrazinamide; Tomography, X-Ray Computed; Travel-Related Illness; Tuberculin Test; Tuberculosis, Miliary; Vitamin B 6 | 2018 |
Prediction of Susceptibility to First-Line Tuberculosis Drugs by DNA Sequencing.
Topics: Antitubercular Agents; Drug Resistance, Bacterial; Ethambutol; Genome, Bacterial; Genotype; Humans; Isoniazid; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Phenotype; Pyrazinamide; Rifampin; Tuberculosis; Whole Genome Sequencing | 2018 |
Pharmacokinetics of First-Line Drugs Among Children With Tuberculosis in Rural Tanzania.
Topics: Adolescent; Antitubercular Agents; Child; Child, Preschool; Drug Therapy, Combination; Ethambutol; Female; HIV Seronegativity; Humans; Infant; Isoniazid; Longitudinal Studies; Male; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Rural Population; Tanzania; Tuberculosis | 2020 |
Catalyst-Substrate Effects on Biocompatible SABRE Hyperpolarization.
Topics: Antitubercular Agents; Biocompatible Materials; Catalysis; Cell Line, Tumor; Cell Survival; Coordination Complexes; Deuterium; Humans; Iridium; Isoniazid; Methane; Pyrazinamide; Substrate Specificity | 2019 |
Differentially Detectable Mycobacterium tuberculosis Cells in Sputum from Treatment-Naive Subjects in Haiti and Their Proportionate Increase after Initiation of Treatment.
Topics: Adult; Antitubercular Agents; Colony Count, Microbial; Drug Therapy, Combination; Female; Haiti; Humans; Isoniazid; Male; Microbiological Techniques; Mycobacterium tuberculosis; Pyrazinamide; Randomized Controlled Trials as Topic; Rifampin; Sputum; Tuberculosis, Pulmonary; Young Adult | 2018 |
Scrofuloderma with disseminated tuberculosis in an Ethiopian child: a case report.
Topics: Anti-Inflammatory Agents; Antitubercular Agents; Child; Ethambutol; Female; Humans; Isoniazid; Mycobacterium tuberculosis; Neck; Prednisolone; Pyrazinamide; Rifampin; Skin; Treatment Outcome; Tuberculosis, Cutaneous | 2018 |
Potentially High Number of Ineffective Drugs with the Standard Shorter Course Regimen for Multidrug-Resistant Tuberculosis Treatment in Haiti.
Topics: Adult; Antitubercular Agents; Coinfection; Drug Resistance, Multiple, Bacterial; Ethambutol; Ethionamide; Female; Fluoroquinolones; Haiti; HIV; HIV Infections; Humans; Isoniazid; Male; Microbial Sensitivity Tests; Middle Aged; Mycobacterium tuberculosis; Pyrazinamide; Retrospective Studies; Treatment Outcome; Tuberculosis, Multidrug-Resistant | 2019 |
Occurrence of disputed rpoB mutations among Mycobacterium tuberculosis isolates phenotypically susceptible to rifampicin in a country with a low incidence of multidrug-resistant tuberculosis.
Topics: Antitubercular Agents; Bacterial Proteins; DNA-Directed RNA Polymerases; Drug Resistance, Multiple, Bacterial; Ethambutol; Genotype; Humans; Incidence; Isoniazid; Kuwait; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Polymerase Chain Reaction; Pyrazinamide; Rifampin; Tuberculosis, Multidrug-Resistant | 2019 |
Isoniazid-Resistant Rifampicin-Susceptible Tuberculosis in Children.
Topics: Antitubercular Agents; Child; Child, Preschool; Contact Tracing; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Prospective Studies; Pyrazinamide; Rifampin; Spain; Tuberculosis, Multidrug-Resistant | 2019 |
Efficacy and tolerability of desensitization in the treatment of delayed drug hypersensitivities to anti-tuberculosis medications.
Topics: Adult; Aged; Aged, 80 and over; Antitubercular Agents; Desensitization, Immunologic; Drug Hypersensitivity; Ethambutol; Female; Humans; Incidence; Isoniazid; Male; Middle Aged; Prospective Studies; Pyrazinamide; Rifampin; Tuberculosis | 2019 |
Conventional and molecular determination of drug resistance in Mycobacterium tuberculosis and Mycobacterium bovis isolates in cattle.
Topics: Animals; Antitubercular Agents; Cattle; Drug Resistance, Bacterial; Ethambutol; Genes, Bacterial; Isoniazid; Microbial Sensitivity Tests; Mutation; Mycobacterium bovis; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Tuberculosis, Bovine | 2019 |
Intestinal dysbiosis compromises alveolar macrophage immunity to Mycobacterium tuberculosis.
Topics: Animals; Antibiotics, Antitubercular; Disease Models, Animal; Drug-Related Side Effects and Adverse Reactions; Dysbiosis; Gastrointestinal Microbiome; Host-Pathogen Interactions; Humans; Immunity, Innate; Immunomodulation; Isoniazid; Macrophages, Alveolar; Mice; Mice, Inbred C57BL; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 2019 |
Metformin induced autophagy in diabetes mellitus - Tuberculosis co-infection patients: A case study.
Topics: Adult; Antitubercular Agents; Autophagy; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Ethambutol; Humans; Hypoglycemic Agents; Insulin; Interferon-gamma; Interleukin-10; Isoniazid; Leukocytes, Mononuclear; Metformin; Microtubule-Associated Proteins; Middle Aged; Pyrazinamide; Rifampin; Sputum; Superoxide Dismutase; Tuberculosis | 2019 |
Tuberculosis drugs' distribution and emergence of resistance in patient's lung lesions: A mechanistic model and tool for regimen and dose optimization.
Topics: Adult; Antitubercular Agents; Decision Support Techniques; Disease Progression; Drug Administration Schedule; Drug Dosage Calculations; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Female; Humans; Isoniazid; Kanamycin; Linezolid; Lung; Male; Middle Aged; Pyrazinamide; Retrospective Studies; Rifampin; Tissue Distribution; Treatment Failure; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Young Adult | 2019 |
The Combination Rifampin-Nitazoxanide, but Not Rifampin-Isoniazid-Pyrazinamide-Ethambutol, Kills Dormant Mycobacterium tuberculosis in Hypoxia at Neutral pH.
Topics: Antitubercular Agents; Drug Combinations; Drug Therapy, Combination; Ethambutol; Humans; Hydrogen-Ion Concentration; Hypoxia; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nitroimidazoles; Oxazolidinones; Pyrazinamide; Rifampin; Tuberculosis | 2019 |
Subtherapeutic Rifampicin Concentration Is Associated With Unfavorable Tuberculosis Treatment Outcomes.
Topics: Antitubercular Agents; Humans; India; Isoniazid; Prospective Studies; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis | 2020 |
Prevailing practices in the treatment of tuberculous meningitis (TBM): a cross-sectional study.
Topics: Anticonvulsants; Antitubercular Agents; Cross-Sectional Studies; Disease Management; Drug Therapy, Combination; Duration of Therapy; Ethambutol; Humans; India; Isoniazid; Levetiracetam; Neurologists; Practice Patterns, Physicians'; Pyrazinamide; Rifampin; Streptomycin; Surveys and Questionnaires; Tuberculosis, Meningeal | 2019 |
Compatibility Between Four Anti-TB Drugs and Tablet Excipients Determined By Microcalorimetry.
Topics: Antitubercular Agents; Calorimetry; Ethambutol; Excipients; Isoniazid; Pyrazinamide; Rifampin | 2019 |
Tuberculosis Meningitis in a 10-Month-Old Living in an Immigrant Township.
Topics: Anti-Bacterial Agents; Antitubercular Agents; Brain; Diagnosis, Differential; Electroencephalography; Emigrants and Immigrants; Ethambutol; Female; Glucocorticoids; Humans; Infant; Isoniazid; Magnetic Resonance Imaging; Prednisone; Pyrazinamide; Rifampin; Romania; Texas; Tuberculosis, Meningeal | 2019 |
First-line tuberculosis drug resistance patterns and associated risk factors in Germany, 2008-2017.
Topics: Adolescent; Adult; Antitubercular Agents; Child; Child, Preschool; Drug Resistance, Multiple, Bacterial; Emigrants and Immigrants; Ethambutol; Female; Germany; Humans; Infant; Isoniazid; Logistic Models; Microbial Sensitivity Tests; Middle Aged; Mycobacterium tuberculosis; Prevalence; Public Health Surveillance; Pyrazinamide; Rifampin; Risk Factors; Streptomycin; Tuberculosis, Multidrug-Resistant | 2019 |
A Rare Case of a Tuberculosis Patient with Sarcoidosis.
Topics: Adult; Antitubercular Agents; Deprescriptions; Ethambutol; Female; Glucocorticoids; Humans; Isoniazid; Prednisolone; Pyrazinamide; Radiography, Thoracic; Rifampin; Romania; Sarcoidosis, Pulmonary; Tomography, X-Ray Computed; Tuberculosis, Pulmonary; Vitamin B 6; Vitamin B Complex | 2019 |
Alternative dosing guidelines to improve outcomes in childhood tuberculosis: a mathematical modelling study.
Topics: Algorithms; Antitubercular Agents; Body Weight; Child Nutrition Disorders; Child, Preschool; Drug Administration Schedule; Humans; Isoniazid; Models, Statistical; Practice Guidelines as Topic; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis | 2019 |
Treatment outcomes of drug-resistant tuberculosis in the Netherlands, 2005-2015.
Topics: Adult; Aged; Antitubercular Agents; Ethambutol; Humans; Incidence; Isoniazid; Logistic Models; Middle Aged; Netherlands; Pyrazinamide; Registries; Retrospective Studies; Rifampin; Risk Factors; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Young Adult | 2019 |
Optimization of a paediatric fixed dose combination mini-tablet and dosing regimen for the first line treatment of tuberculosis.
Topics: Adult; Antitubercular Agents; Child; Humans; Isoniazid; Pyrazinamide; Rifampin; Tablets; Tuberculosis | 2019 |
Model-Based Relationship between the Molecular Bacterial Load Assay and Time to Positivity in Liquid Culture.
Topics: Antitubercular Agents; Bacterial Load; Biological Assay; Biomarkers, Pharmacological; Computer Simulation; DNA, Bacterial; Drug Dosage Calculations; Drug Monitoring; Ethambutol; Female; Humans; Isoniazid; Malawi; Male; Models, Statistical; Mozambique; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Sputum; Tanzania; Time Factors; Tuberculosis, Pulmonary | 2019 |
Fluoroquinolones and isoniazid-resistant tuberculosis: implications for the 2018 WHO guidance.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Drug Therapy, Combination; Duration of Therapy; Ethambutol; Female; Fluoroquinolones; Humans; Isoniazid; Levofloxacin; Logistic Models; London; Male; Middle Aged; Practice Guidelines as Topic; Pyrazinamide; Recurrence; Retrospective Studies; Rifampin; Treatment Failure; Tuberculosis, Multidrug-Resistant; World Health Organization; Young Adult | 2019 |
Long-term efficacy of 6-month therapy with isoniazid and rifampin compared with isoniazid, rifampin, and pyrazinamide treatment for pleural tuberculosis.
Topics: Adolescent; Adult; Antitubercular Agents; Case-Control Studies; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Spain; Treatment Outcome; Tuberculosis, Pleural; Young Adult | 2019 |
Individualising therapy for drug-sensitive tuberculosis.
Topics: Antitubercular Agents; Drug Resistance, Microbial; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Precision Medicine; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 2019 |
Rod-like Co based metal-organic framework embedded into mesoporous carbon composite modified glassy carbon electrode for effective detection of pyrazinamide and isonicotinyl hydrazide in biological samples.
Topics: Blood Chemical Analysis; Carbon; Catalysis; Cobalt; Electrochemistry; Electrodes; Glass; Humans; Isoniazid; Limit of Detection; Metal-Organic Frameworks; Oxidation-Reduction; Porosity; Pyrazinamide; Urinalysis | 2019 |
Pancreatic tuberculosis diagnosed by endoscopic ultrasound-guided fine needle aspiration in a 14-year-old adolescent.
Topics: Abdominal Pain; Adolescent; Antitubercular Agents; Cote d'Ivoire; Drug Therapy, Combination; Endoscopic Ultrasound-Guided Fine Needle Aspiration; Humans; Isoniazid; Male; Pancreatitis; Pyrazinamide; Rifampin; Travel-Related Illness; Tuberculosis | 2020 |
Determinants of serum concentration of first-line anti-tuberculosis drugs from China.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antitubercular Agents; Case-Control Studies; China; Chromatography, Liquid; Creatinine; Dose-Response Relationship, Drug; Drug Monitoring; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Retrospective Studies; Rifampin; Sex Factors; Smoking; Tuberculosis; Young Adult | 2019 |
[Tuberculosis].
Topics: Antitubercular Agents; Ethambutol; Humans; Isoniazid; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Tuberculosis; Tuberculosis, Multidrug-Resistant | 2019 |
Association of ABCC Gene Polymorphism With Susceptibility to Antituberculosis Drug-Induced Hepatotoxicity in Western Han Patients With Tuberculosis.
Topics: Adult; Alanine Transaminase; Antitubercular Agents; Asian People; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; China; Drug Therapy, Combination; Ethambutol; Female; Genetic Predisposition to Disease; Genotype; Humans; Isoniazid; Male; Middle Aged; Multidrug Resistance-Associated Protein 2; Polymorphism, Single Nucleotide; Pyrazinamide; Rifampin; Risk Factors; Sex Factors; Tuberculosis; Young Adult | 2020 |
Effect of diabetes mellitus on TB drug concentrations in Tanzanian patients.
Topics: Adult; Aged; Aged, 80 and over; Antitubercular Agents; Diabetes Complications; Diabetes Mellitus; Female; Humans; Isoniazid; Male; Middle Aged; Plasma; Prospective Studies; Pyrazinamide; Rifampin; Tanzania; Treatment Outcome; Tuberculosis, Pulmonary; Young Adult | 2019 |
Lack of Weight Gain During the First 2 Months of Treatment and Human Immunodeficiency Virus Independently Predict Unsuccessful Treatment Outcomes in Tuberculosis.
Topics: Adult; Antitubercular Agents; Brazil; Ethambutol; Female; HIV Seropositivity; Humans; Isoniazid; Male; Middle Aged; Proportional Hazards Models; Prospective Studies; Pyrazinamide; Rifampin; Time Factors; Treatment Outcome; Tuberculosis, Pulmonary; Weight Gain | 2020 |
Vibrational spectra of pyrazinamide and isoniazid studied by terahertz spectroscopy and density functional theory.
Topics: Crystallization; Density Functional Theory; Dimerization; Isoniazid; Molecular Conformation; Pyrazinamide; Quantum Theory; Terahertz Spectroscopy; Vibration | 2020 |
Exposure to first line anti-tuberculosis drugs in prepubertal age reduces the quality and functional competence of spermatozoa and oocytes in Swiss albino mice.
Topics: Animals; Antitubercular Agents; Cell Nucleus; Ethambutol; Female; Isoniazid; Male; Metaphase; Mice; Oocytes; Pharmaceutical Preparations; Pregnancy; Pyrazinamide; Rifampin; Spermatozoa; Streptomycin | 2020 |
Miliary tuberculosis and choroidal tuberculoma in a three-month old baby girl: Diagnosis and follow-up of a case.
Topics: Adrenal Cortex Hormones; Amikacin; Antitubercular Agents; Choroid Diseases; Drug Therapy, Combination; Ethambutol; Female; Humans; Infant; Isoniazid; Ophthalmoscopy; Pyrazinamide; Rifampin; Tuberculoma; Tuberculosis, Miliary; Tuberculosis, Ocular; Uveitis, Posterior | 2020 |
Rapid and highly sensitive quantification of the anti-tuberculosis agents isoniazid, ethambutol, pyrazinamide, rifampicin and rifabutin in human plasma by UPLC-MS/MS.
Topics: AIDS-Related Opportunistic Infections; Antitubercular Agents; Calibration; Chromatography, High Pressure Liquid; Drug Monitoring; Ethambutol; Humans; Isoniazid; Pyrazinamide; Reference Standards; Reproducibility of Results; Rifabutin; Rifampin; Sensitivity and Specificity; Tandem Mass Spectrometry; Tuberculosis | 2020 |
Early antituberculosis drug exposure in hospitalized patients with human immunodeficiency virus-associated tuberculosis.
Topics: Adult; Antitubercular Agents; Female; HIV; HIV Infections; Humans; Isoniazid; Male; Pyrazinamide; Tuberculosis | 2020 |
Presumed Intraocular Tuberculosis Manifesting as Unilateral Iris Granuloma.
Topics: Adult; Antitubercular Agents; Drug Therapy, Combination; Ethambutol; Granuloma; Humans; Iris Diseases; Isoniazid; Male; Microscopy, Acoustic; Pyrazinamide; Rifampin; Tuberculin Test; Tuberculosis, Ocular | 2020 |
Whole-genome sequencing in drug susceptibility testing of Mycobacterium tuberculosis in routine practice in Lyon, France.
Topics: Antitubercular Agents; Bacterial Proteins; DNA-Directed RNA Polymerases; Drug Resistance, Multiple, Bacterial; Ethambutol; France; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pentosyltransferases; Pyrazinamide; Rifampin; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Whole Genome Sequencing | 2020 |
Molecular identification of mutations conferring resistance to rifampin, isoniazid and pyrazinamide among
Topics: Antitubercular Agents; Bacterial Proteins; DNA, Bacterial; Humans; Iran; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Promoter Regions, Genetic; Pyrazinamide; Rifampin | 2020 |
LC-QToF-MS method for quantification of ethambutol, isoniazid, pyrazinamide and rifampicin in human plasma and its application.
Topics: Antitubercular Agents; Chromatography, High Pressure Liquid; Ethambutol; Humans; Isoniazid; Mass Spectrometry; Plasma; Pyrazinamide; Rifampin | 2020 |
High-Dose First-Line Treatment Regimen for Recurrent Rifampicin-Susceptible Tuberculosis.
Topics: Humans; Isoniazid; Pyrazinamide; Rifampin; Tuberculosis; Tuberculosis, Multidrug-Resistant | 2020 |
Reply to Decroo
Topics: Humans; Isoniazid; Pyrazinamide; Rifampin; Tuberculosis; Tuberculosis, Multidrug-Resistant | 2020 |
Drug-Induced Liver Injury from Anti-Tuberculosis Treatment: A Retrospective Cohort Study.
Topics: Adult; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Female; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Retrospective Studies; Rifampin; Risk Factors; Tuberculosis; Young Adult | 2020 |
Cytochemical Evaluation of the Toxic Effects of Combined Antituberculosis Substances on Metabolic State of Blood Lymphocytes.
Topics: Acid Phosphatase; Administration, Oral; Animals; Animals, Outbred Strains; Antitubercular Agents; Drug Combinations; Esterases; Ethambutol; Fluoroquinolones; Gene Expression; Glycerolphosphate Dehydrogenase; Isoniazid; L-Lactate Dehydrogenase; Lymphocytes; Male; Primary Cell Culture; Prothionamide; Pyrazinamide; Rats; Rifampin; Succinate Dehydrogenase | 2020 |
Tuberculous meningitis manifesting with neuroregression in a eleven month child.
Topics: Acetazolamide; Antitubercular Agents; Carbonic Anhydrase Inhibitors; Cerebrospinal Fluid; Early Medical Intervention; Ethambutol; Female; Glucocorticoids; Humans; Hydrocephalus; Infant; Isoniazid; Magnetic Resonance Imaging; Neurodevelopmental Disorders; Nucleic Acid Amplification Techniques; Prednisolone; Pyrazinamide; Rifampin; Stomach; Treatment Outcome; Tuberculosis, Meningeal | 2020 |
Treatment outcome of tuberculosis treatment regimens in Kandahar, Afghanistan.
Topics: Adolescent; Adult; Afghanistan; Antitubercular Agents; Cohort Studies; Cough; Drug Therapy, Combination; Duration of Therapy; Ethambutol; Female; Fever; Humans; Isoniazid; Male; Middle Aged; Mortality; Prognosis; Pyrazinamide; Retreatment; Retrospective Studies; Rifampin; Sex Distribution; Sputum; Treatment Failure; Treatment Outcome; Tuberculosis, Pulmonary; Weight Loss; Young Adult | 2020 |
Primary tuberculosis of the glans penis in an immunocompetent male.
Topics: Adult; Antitubercular Agents; Ethambutol; Humans; Isoniazid; Male; Penile Diseases; Pyrazinamide; Rifampin; Tuberculosis, Male Genital | 2020 |
Gene expression responses to anti-tuberculous drugs in a whole blood model.
Topics: Antitubercular Agents; Bacterial Proteins; Blood; Drug Combinations; Drug Repositioning; Ethambutol; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Humans; Isoniazid; Models, Biological; Mycobacterium tuberculosis; Oligonucleotide Array Sequence Analysis; Pyrazinamide; Rifampin; Sputum | 2020 |
Esophageal Tuberculosis - A Mass of Confusion.
Topics: Aged; Antitubercular Agents; Deglutition Disorders; Delayed Diagnosis; Diagnosis, Differential; Directly Observed Therapy; Endoscopy, Digestive System; Esophageal Neoplasms; Esophagitis; Ethambutol; Fever; Humans; Isoniazid; Lymph Nodes; Lymphadenopathy; Male; Mexican Americans; Pyrazinamide; Rifampin; Substance-Related Disorders; Tomography, X-Ray Computed; Tuberculosis, Gastrointestinal; Ultrasonography | 2020 |
A Complete Triad: Horner's Syndrome in Tuberculous Meningitis.
Topics: Antitubercular Agents; Brain; Ethambutol; Horner Syndrome; Humans; Immunocompetence; Isoniazid; Male; Nucleic Acid Amplification Techniques; Pyrazinamide; Pyridoxine; Rifampin; Tomography, X-Ray Computed; Tuberculosis, Meningeal; Uganda; Young Adult | 2020 |
Fully weekly antituberculosis regimen: a proof-of-concept study.
Topics: Animals; Antitubercular Agents; Drug Administration Schedule; Drug Therapy, Combination; Isoniazid; Mice; Mycobacterium tuberculosis; Pyrazinamide; Tuberculosis | 2020 |
Bile acids, lipid and purine metabolism involved in hepatotoxicity of first-line anti-tuberculosis drugs.
Topics: Animals; Antitubercular Agents; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Drug Therapy, Combination; Isoniazid; Lipid Metabolism; Male; Mass Spectrometry; Metabolomics; Mice; Mice, Inbred C57BL; Mice, Knockout; Purines; Pyrazinamide; Receptors, Cytoplasmic and Nuclear; Rifampin | 2020 |
A biochemically-interpretable machine learning classifier for microbial GWAS.
Topics: Aminosalicylic Acid; Anti-Bacterial Agents; Drug Resistance, Bacterial; Genome-Wide Association Study; Genome, Bacterial; Genome, Microbial; Isoniazid; Machine Learning; Mycobacterium tuberculosis; Pyrazinamide; Reproducibility of Results | 2020 |
Inclusion of Mechanical Ventilation in Severity Staging of Tuberculous Meningitis Improves Outcome Prediction.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Antitubercular Agents; Child; Child, Preschool; Consciousness Disorders; Ethambutol; Female; Humans; Hydrocephalus; India; Isoniazid; Magnetic Resonance Imaging; Male; Middle Aged; Prognosis; Pyrazinamide; Registries; Respiration, Artificial; Rifampin; Seizures; Severity of Illness Index; Tomography, X-Ray Computed; Tuberculosis, Meningeal; Ventriculoperitoneal Shunt; Young Adult | 2020 |
An Evaluation of the In Vitro Roles and Mechanisms of Silibinin in Reducing Pyrazinamide- and Isoniazid-Induced Hepatocellular Damage.
Topics: Antitubercular Agents; Apoptosis; Cell Line; Chemical and Drug Induced Liver Injury; Hepatocytes; Humans; Isoniazid; Oxidative Stress; Protective Agents; Protein Carbonylation; Pyrazinamide; Silybin | 2020 |
Survey of drug resistance associated gene mutations in Mycobacterium tuberculosis, ESKAPE and other bacterial species.
Topics: Antitubercular Agents; Bacterial Proteins; Data Curation; Databases, Genetic; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Extensively Drug-Resistant Tuberculosis; Fluoroquinolones; Isoniazid; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Sequence Analysis, DNA; Tuberculosis, Multidrug-Resistant | 2020 |
Tuberculosis sepsis after tocilizumab treatment.
Topics: Antibodies, Monoclonal, Humanized; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Middle Aged; Multiple Organ Failure; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Sepsis; Treatment Outcome; Tuberculosis | 2020 |
Ocular adverse events in drug sensitive TB patients on daily fixed dose combination anti-TB drugs: A record review study from Kerala, India.
Topics: Adult; Aged; Antitubercular Agents; Dose-Response Relationship, Drug; Drug Combinations; Ethambutol; Eye Diseases; Female; Humans; India; Isoniazid; Male; Middle Aged; Pyrazinamide; Retrospective Studies; Rifampin; Tuberculosis; Vision Disorders | 2020 |
An Unexpected Cause of Conjunctivitis in an Adolescent.
Topics: Adolescent; Antitubercular Agents; Conjunctivitis; Diagnosis, Differential; Ethambutol; Glucocorticoids; Humans; Isoniazid; Male; Prednisolone; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 2020 |
Primary breast tuberculosis in an HIV-infected patient.
Topics: Adult; Antitubercular Agents; Biopsy; Breast; Ethambutol; Female; HIV Infections; Humans; Isoniazid; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis | 2020 |
Evidence of drug-induced hepatotoxicity in the Maghrebian population.
Topics: Adolescent; Adult; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Isoniazid; Liver Diseases; Male; Middle Aged; Pyrazinamide; Young Adult | 2022 |
Intestinal tuberculosis in a patient with end-stage renal disease on hemodialysis: A case report.
Topics: Anorexia; Antitubercular Agents; Drug Combinations; Ethambutol; Humans; Isoniazid; Kidney Failure, Chronic; Male; Middle Aged; Muscle Weakness; Pyrazinamide; Renal Dialysis; Republic of Korea; Rifampin; Tomography, X-Ray Computed; Tuberculosis, Gastrointestinal | 2020 |
Initial resistance to companion drugs should not be considered an exclusion criterion for the shorter multidrug-resistant tuberculosis treatment regimen.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Bangladesh; Child; Child, Preschool; Clinical Protocols; Ethambutol; Female; Fluoroquinolones; Humans; Isoniazid; Male; Microbial Sensitivity Tests; Middle Aged; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Time Factors; Tuberculosis, Multidrug-Resistant; Young Adult | 2020 |
Intrapulmonary Pharmacokinetics of First-line Anti-tuberculosis Drugs in Malawian Patients With Tuberculosis.
Topics: Antitubercular Agents; Bayes Theorem; Ethambutol; Humans; Isoniazid; Pyrazinamide; Tuberculosis | 2021 |
Isoniazid resistance profile and associated levofloxacin and pyrazinamide resistance in rifampicin resistant and sensitive isolates/from pulmonary and extrapulmonary tuberculosis patients in Pakistan: A laboratory based surveillance study 2015-19.
Topics: Adolescent; Adult; Antitubercular Agents; Child; Child, Preschool; Drug Resistance, Bacterial; Epidemiological Monitoring; Female; Genotype; Humans; Infant; Isoniazid; Laboratories; Levofloxacin; Male; Microbial Sensitivity Tests; Pakistan; Phenotype; Pyrazinamide; Retrospective Studies; Rifampin; Tuberculosis, Multidrug-Resistant; Young Adult | 2020 |
Cyclic Peptide [R
Topics: Adolescent; Adult; Aged; Antibiotics, Antitubercular; Autophagy; Cytokines; Drug Therapy, Combination; Granuloma; Host-Pathogen Interactions; Humans; Isoniazid; Microbial Viability; Middle Aged; Mycobacterium tuberculosis; Oxidative Stress; Peptides, Cyclic; Pyrazinamide; Tuberculosis; Young Adult | 2020 |
Hemophagocytic syndrome associated with Mycobacterium bovis in a patient with X-SCID: a case report.
Topics: Antibiotics, Antitubercular; High-Throughput Nucleotide Sequencing; Humans; Infant; Interleukin Receptor Common gamma Subunit; Isoniazid; Lymphohistiocytosis, Hemophagocytic; Male; Mutation; Mycobacterium bovis; Mycobacterium tuberculosis; Patient Discharge; Polymerase Chain Reaction; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis; X-Linked Combined Immunodeficiency Diseases | 2020 |
Management of isoniazid-monoresistant tuberculosis (Hr-TB) in Queensland, Australia: a retrospective case series.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antitubercular Agents; Australia; Child; Child, Preschool; Drug Therapy, Combination; Ethambutol; Ethinyl Estradiol-Norgestrel Combination; Female; Fluoroquinolones; Humans; Isoniazid; Levofloxacin; Male; Middle Aged; Pyrazinamide; Retrospective Studies; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Young Adult | 2020 |
Effect of interval between food intake and drug administration at fasting condition on the plasma concentrations of first-line anti-tuberculosis drugs in Chinese population.
Topics: Administration, Oral; Adult; Antitubercular Agents; China; Drug Administration Schedule; Eating; Ethambutol; Fasting; Female; Humans; Isoniazid; Male; Pyrazinamide; Rifampin; Time Factors; Treatment Outcome; Tuberculosis, Pulmonary | 2020 |
Population Pharmacokinetic Properties of Antituberculosis Drugs in Vietnamese Children with Tuberculous Meningitis.
Topics: Adult; Antitubercular Agents; Asian People; Child; Ethambutol; Humans; Isoniazid; Pyrazinamide; Tuberculosis, Meningeal | 2020 |
Tuberculosis in the intensive care unit: alternative treatment regimens and association with mortality.
Topics: Adult; Amikacin; Antibiotics, Antitubercular; APACHE; Brazil; Drug Administration Routes; Drug Administration Schedule; Drug Therapy, Combination; Ethambutol; Female; Humans; Intensive Care Units; Isoniazid; Logistic Models; Male; Middle Aged; Multivariate Analysis; Pyrazinamide; Retrospective Studies; Rifampin; Streptomycin; Tuberculosis | 2021 |
Quantification of pyrazinamide, isoniazid, acetyl-isoniazid, and rifampicin by a high-performance liquid chromatography method in human plasma from patients with tuberculosis.
Topics: Adult; Aged; Chromatography, High Pressure Liquid; Female; Humans; Isoniazid; Male; Middle Aged; Pilot Projects; Prospective Studies; Pyrazinamide; Quality Control; Rifampin; Tuberculosis | 2021 |
Dry powder inhalation formulation of chitosan nanoparticles for co-administration of isoniazid and pyrazinamide.
Topics: Administration, Inhalation; Animals; Antitubercular Agents; Cell Line; Chemistry, Pharmaceutical; Chitosan; Drug Combinations; Dry Powder Inhalers; Excipients; Freeze Drying; Humans; Isoniazid; Macrophages, Alveolar; Nanoparticles; Particle Size; Polyphosphates; Pyrazinamide; Rats | 2021 |
Point-of-Care Ultrasound Image of Intra-Abdominal Lymphadenopathy in Tuberculosis.
Topics: Abdomen; Antitubercular Agents; Ethambutol; Female; Humans; Isoniazid; Lymph Nodes; Lymphadenopathy; Mycobacterium tuberculosis; Point-of-Care Systems; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis; Ultrasonography; Young Adult | 2020 |
Tackling quantitative polymorphic analysis through fixed-dose combination tablets production. Pyrazinamide polymorphic assessment.
Topics: Antitubercular Agents; Ethambutol; Humans; Isoniazid; Least-Squares Analysis; Pyrazinamide; Tablets | 2021 |
Ameliorative potential of Adhatoda vasica against anti-tubercular drugs induced hepatic impairments in female Wistar rats in relation to oxidative stress and xeno-metabolism.
Topics: Alkaloids; Animals; Antitubercular Agents; Arylamine N-Acetyltransferase; Chemical and Drug Induced Liver Injury; Cholesterol 7-alpha-Hydroxylase; Cytochrome P-450 CYP2E1; Disease Models, Animal; Female; Free Radical Scavengers; Gene Expression Regulation; Glucuronosyltransferase; Isoniazid; Justicia; Oxidative Stress; Plant Extracts; Plant Leaves; Pregnane X Receptor; Pyrazinamide; Quinazolines; Rats, Wistar; Rifampin | 2021 |
INTENSIVE TREATMENT OF A CAPTIVE BORNEAN ELEPHANT (
Topics: Administration, Rectal; Animals; Anti-Bacterial Agents; Antitubercular Agents; Bacterial Proteins; Elephants; Isoniazid; Japan; Levofloxacin; Mycobacterium; Mycobacterium Infections; Pyrazinamide | 2021 |
Successful Use of Rifamycin-Sparing Regimens for the Treatment of Active Tuberculosis in Lung Transplant Recipients.
Topics: Ethambutol; Humans; Isoniazid; Lung; Lung Transplantation; Moxifloxacin; Pyrazinamide; Rifamycins; Transplant Recipients; Treatment Outcome; Tuberculosis | 2021 |
Facile synthesis and antimycobacterial activity of isoniazid, pyrazinamide and ciprofloxacin derivatives.
Topics: Animals; Antitubercular Agents; Binding Sites; Catalytic Domain; Cell Survival; Chlorocebus aethiops; Ciprofloxacin; DNA Gyrase; Drug Design; Drug Resistance, Bacterial; Isoniazid; Microbial Sensitivity Tests; Molecular Conformation; Molecular Docking Simulation; Mycobacterium tuberculosis; Nontuberculous Mycobacteria; Pyrazinamide; Structure-Activity Relationship; Vero Cells | 2021 |
Effectiveness of Shorter Treatment Regimen in Multidrug-Resistant Tuberculosis Patients in Pakistan: A Multicenter Retrospective Record Review.
Topics: Adult; Amikacin; Antitubercular Agents; Clofazimine; Drug Administration Schedule; Drug Resistance, Multiple, Bacterial; Ethambutol; Ethionamide; Female; Humans; Isoniazid; Lost to Follow-Up; Male; Middle Aged; Moxifloxacin; Mycobacterium tuberculosis; Pakistan; Pyrazinamide; Retrospective Studies; Survival Analysis; Treatment Failure; Tuberculosis, Multidrug-Resistant | 2021 |
Five-year microevolution of a multidrug-resistant Mycobacterium tuberculosis strain within a patient with inadequate compliance to treatment.
Topics: Adult; Antitubercular Agents; Argentina; Drug Resistance, Multiple, Bacterial; Female; Humans; Isoniazid; Medication Adherence; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Phylogeny; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Whole Genome Sequencing | 2021 |
A Rare Case of Disseminated Tuberculosis and Hematological Malignancy in a Heart Transplant Recipient.
Topics: Aged; Antitubercular Agents; Heart Transplantation; Hematologic Neoplasms; Humans; Isoniazid; Male; Pyrazinamide; Tuberculosis, Miliary | 2021 |
Pharmacokinetics of First-Line Drugs in Children With Tuberculosis, Using World Health Organization-Recommended Weight Band Doses and Formulations.
Topics: Adult; Antitubercular Agents; Child; Child, Preschool; Ethambutol; Female; Humans; Isoniazid; Male; Pyrazinamide; Rifampin; Tuberculosis; World Health Organization | 2022 |
Simultaneous determination of three antituberculosis drugs in the serum of patients with spinal tuberculosis by capillary electrophoresis.
Topics: Antitubercular Agents; Electrophoresis, Capillary; Humans; Isoniazid; Pyrazinamide; Tuberculosis, Spinal | 2021 |
A hydrogel-based implantable multidrug antitubercular formulation outperforms oral delivery.
Topics: Animals; Antitubercular Agents; Ethambutol; Hydrogels; Isoniazid; Mice; Pyrazinamide | 2021 |
Early phase of effective treatment induces distinct transcriptional changes in Mycobacterium tuberculosis expelled by pulmonary tuberculosis patients.
Topics: Adult; Antitubercular Agents; Ethambutol; Female; Humans; Isoniazid; Male; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Transcriptome; Treatment Outcome; Tuberculosis, Pulmonary; Young Adult | 2021 |
Images in Clinical Tropical Medicine.
Topics: Adolescent; Antitubercular Agents; Ethambutol; Humans; Isoniazid; Knee; Lupus Vulgaris; Male; Pyrazinamide; Rifampin | 2021 |
Optimizing Dosing and Fixed-Dose Combinations of Rifampicin, Isoniazid, and Pyrazinamide in Pediatric Patients With Tuberculosis: A Prospective Population Pharmacokinetic Study.
Topics: Adult; Antitubercular Agents; Child; Drug Combinations; Ethambutol; Female; Humans; Infant; Isoniazid; Male; Prospective Studies; Pyrazinamide; Rifampin; Tablets; Tuberculosis | 2022 |
No implication of HIV coinfection on the plasma exposure to rifampicin, pyrazinamide, and ethambutol in tuberculosis patients.
Topics: Adult; Antitubercular Agents; Ethambutol; HIV Infections; Humans; Isoniazid; Pyrazinamide; Rifampin; Tuberculosis | 2022 |
LC-MS/MS method for simultaneous quantification of the first-line anti-tuberculosis drugs and six primary metabolites in patient plasma: Implications for therapeutic drug monitoring.
Topics: Antitubercular Agents; Chromatography, High Pressure Liquid; Drug Monitoring; Ethambutol; Humans; Isoniazid; Plasma; Pyrazinamide; Rifampin; Tandem Mass Spectrometry; Tuberculosis | 2021 |
High-dose gatifloxacin-based shorter treatment regimens for MDR/RR-TB.
Topics: Antitubercular Agents; Gatifloxacin; Humans; Isoniazid; Pyrazinamide; Treatment Outcome; Tuberculosis, Multidrug-Resistant | 2022 |
Neurodevelopmental toxicity of pyrazinamide to larval zebrafish and the restoration after intoxication withdrawal.
Topics: Animals; Antitubercular Agents; Isoniazid; Larva; Pyrazinamide; Zebrafish | 2022 |
Interim Guidance: 4-Month Rifapentine-Moxifloxacin Regimen for the Treatment of Drug-Susceptible Pulmonary Tuberculosis - United States, 2022.
Topics: Antitubercular Agents; Centers for Disease Control and Prevention, U.S.; Drug Administration Schedule; Drug Therapy, Combination; Humans; Isoniazid; Moxifloxacin; Pyrazinamide; Randomized Controlled Trials as Topic; Rifampin; Tuberculosis, Pulmonary; United States | 2022 |
A case report. Rediscovering tuberculostatics drugs: skin rash and pyrazinamide.
Topics: Antitubercular Agents; Exanthema; Humans; Isoniazid; Pyrazinamide | 2022 |
Prediction of lung exposure to anti-tubercular drugs using plasma pharmacokinetic data: Implications for dose selection.
Topics: Animals; Antitubercular Agents; Ethambutol; Humans; Isoniazid; Lung; Mice; Pyrazinamide; Tuberculosis | 2022 |
Novel Regimens of Bedaquiline-Pyrazinamide Combined with Moxifloxacin, Rifabutin, Delamanid and/or OPC-167832 in Murine Tuberculosis Models.
Topics: Animals; Antibiotics, Antitubercular; Antitubercular Agents; Diarylquinolines; Disease Models, Animal; Drug Administration Schedule; Drug Therapy, Combination; Isoniazid; Mice; Mice, Inbred BALB C; Moxifloxacin; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Pyrazinamide; Rifabutin; Tuberculosis | 2022 |
High Intrapulmonary Rifampicin and Isoniazid Concentrations Are Associated With Rapid Sputum Bacillary Clearance in Patients With Pulmonary Tuberculosis.
Topics: Adult; Antitubercular Agents; Bacillus; Ethambutol; Humans; Isoniazid; Pyrazinamide; Rifampin; Sputum; Tuberculosis, Pulmonary | 2022 |
Assessment of the efficacy of clofazimine alone and in combination with primary agents against Mycobacterium tuberculosis in vitro.
Topics: Animals; Antitubercular Agents; Clofazimine; Ethambutol; Humans; Isoniazid; Mice; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Tuberculosis | 2022 |
Drug concentration at the site of disease in children with pulmonary tuberculosis.
Topics: Adult; Antitubercular Agents; Child; Ethambutol; Humans; Infant; Isoniazid; Pyrazinamide; South Africa; Tuberculosis, Pulmonary | 2022 |
Analysis of Adverse Drug Reactions to First-Line Anti-Tuberculosis Drugs Using the Korea Adverse Event Reporting System.
Topics: Antitubercular Agents; Drug-Related Side Effects and Adverse Reactions; Ethambutol; Humans; Isoniazid; Pyrazinamide; Republic of Korea; Rifampin | 2022 |
Primary psoas tuberculosis abscess with an iliac bone lytic lesion: a case report.
Topics: Adult; Antitubercular Agents; Female; Humans; Isoniazid; Psoas Abscess; Pyrazinamide; Rifampin; Tuberculosis | 2022 |
Diagnostic Accuracy of Therapeutic Drug Monitoring During Tuberculosis Treatment.
Topics: Antitubercular Agents; Drug Monitoring; Ethambutol; HIV Infections; Humans; Isoniazid; Pyrazinamide; Rifampin; Tuberculosis | 2022 |
Enteropathogen spectrum and effect on antimycobacterial pharmacokinetics among children with tuberculosis in rural Tanzania: a prospective cohort study.
Topics: Antitubercular Agents; Child; Cohort Studies; Ethambutol; Female; Humans; Isoniazid; Male; Prospective Studies; Pyrazinamide; Rifampin; Tanzania; Tuberculosis; United States | 2022 |
IFN-γ ELISpot in Severe Cutaneous Adverse Reactions to First-Line Antituberculosis Drugs in an HIV Endemic Setting.
Topics: Antitubercular Agents; Ethambutol; HIV Infections; Humans; Interferon-gamma; Isoniazid; Pyrazinamide; Rifampin; Stevens-Johnson Syndrome | 2022 |
The role of the farnesoid X receptor in quadruple anti-tuberculosis drug-induced liver injury.
Topics: Animals; Antitubercular Agents; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liver Injury, Chronic; Ethambutol; Isoniazid; Liver; Pyrazinamide; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Rifampin | 2022 |
Altered drug exposures of first-line TB drugs in a moxifloxacin-containing treatment regimen.
Topics: Antitubercular Agents; Drug Therapy, Combination; Humans; Isoniazid; Moxifloxacin; Pregnanes; Pyrazinamide; Rifampin; South Africa; Tuberculosis | 2022 |
Superior Efficacy of a TBI-166, Bedaquiline, and Pyrazinamide Combination Regimen in a Murine Model of Tuberculosis.
Topics: Animals; Antitubercular Agents; Clofazimine; Diarylquinolines; Disease Models, Animal; Isoniazid; Linezolid; Mice; Mice, Inbred BALB C; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Tuberculosis; Tuberculosis, Multidrug-Resistant | 2022 |
Prediction of drug resistance by Sanger sequencing of Mycobacterium tuberculosis complex strains isolated from multidrug resistant tuberculosis suspect patients in Ethiopia.
Topics: Antitubercular Agents; Drug Resistance, Multiple, Bacterial; Ethambutol; Ethiopia; Humans; Isoniazid; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Multidrug-Resistant | 2022 |
A national, multicentre web-based point prevalence survey of antimicrobial use in community healthcare centres across South Africa and the implications.
Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Community Health Services; Ethambutol; Humans; Internet; Isoniazid; Prevalence; Pyrazinamide; Rifampin; South Africa | 2022 |
Comparison of different regimens with or without fluoroquinolone in isoniazid-resistant tuberculosis: A multicenter cohort study.
Topics: Antitubercular Agents; Cohort Studies; Drug Therapy, Combination; Ethambutol; Fluoroquinolones; Humans; Isoniazid; Pyrazinamide; Retrospective Studies; Rifampin; Tuberculosis, Multidrug-Resistant | 2022 |
Dimethyl fumarate eliminates differentially culturable
Topics: Animals; Antitubercular Agents; Dimethyl Fumarate; Disease Models, Animal; Humans; Isoniazid; Mice; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Tuberculosis, Lymph Node | 2022 |
Tuberculosis: Common Questions and Answers.
Topics: Antitubercular Agents; Ethambutol; Humans; Isoniazid; Latent Tuberculosis; Pyrazinamide; Rifampin; Tuberculin; Tuberculosis; United States | 2022 |
Pyrazinamide resistance in rifampicin discordant tuberculosis.
Topics: Antitubercular Agents; Humans; Isoniazid; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Pyrazinamide; Rifabutin; Rifampin; South Africa; Tuberculosis; Tuberculosis, Multidrug-Resistant | 2022 |
Chronic purulent pericarditis: case report.
Topics: Adult; COVID-19; Ethambutol; Humans; Isoniazid; Male; Mediastinitis; Pericarditis; Pericardium; Pyrazinamide; Rifampin; Sclerosis; Suppuration | 2022 |
Sex Differences in TB Clinical Presentation, Drug Exposure, and Treatment Outcomes in India.
Topics: Antitubercular Agents; Female; Humans; India; Isoniazid; Male; Prospective Studies; Pyrazinamide; Rifampin; Sex Characteristics; Treatment Outcome | 2023 |
A Mycobacterium tuberculosis-Infected Patient Who Could Not Tolerate Oral Intake Successfully Treated Using an Intravenous Tedizolid-Containing Regimen.
Topics: Aged; Anti-Bacterial Agents; Antitubercular Agents; Cutaneous Fistula; Ethambutol; Humans; Isoniazid; Levofloxacin; Linezolid; Male; Meropenem; Micafungin; Mycobacterium tuberculosis; Oxazolidinones; Pyrazinamide; Rifampin; Streptomycin; Teicoplanin; Tetrazoles; Tuberculosis | 2022 |
Validation and application of a quantitative LC-MS/MS assay for the analysis of first-line anti-tuberculosis drugs, rifabutin and their metabolites in human breast milk.
Topics: Antitubercular Agents; Chromatography, Liquid; Ethambutol; Female; Humans; Isoniazid; Milk, Human; Pyrazinamide; Rifabutin; Rifampin; Tandem Mass Spectrometry | 2022 |
Pyridine-N-Oxide Alkaloids from
Topics: Alkaloids; Allium; Antitubercular Agents; Disulfides; Isoniazid; Ligands; Molecular Docking Simulation; Mycobacterium tuberculosis; Oxides; Pyrazinamide; Pyridines | 2022 |
In silico evaluation of WHO-endorsed molecular methods to detect drug resistant tuberculosis.
Topics: Amikacin; Antitubercular Agents; Capreomycin; Genotype; Humans; Isoniazid; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Tuberculosis, Multidrug-Resistant; World Health Organization | 2022 |
Topics: Ethambutol; Genotype; Humans; Isoniazid; Mycobacterium tuberculosis; Pilot Projects; Pyrazinamide; Rifampin; Timor-Leste | 2022 |
Development and Optimization of a New UPLC-UV/MS Method through DoE and MLR for Detecting Substandard Drug Products to Treat Tuberculosis.
Topics: Antitubercular Agents; Chromatography, Liquid; Ethambutol; Humans; Isoniazid; Pyrazinamide; Rifampin; Substandard Drugs; Tablets; Tuberculosis | 2022 |
A high-throughput LC-MS/MS method for simultaneous determination of isoniazid, ethambutol and pyrazinamide in human plasma.
Topics: Antitubercular Agents; Chromatography, High Pressure Liquid; Chromatography, Liquid; Ethambutol; Humans; Isoniazid; Pyrazinamide; Tandem Mass Spectrometry; Tuberculosis | 2023 |
Naringenin protects hepato-renal tissues against antituberculosis drugs induced toxic manifestations by modulating interleukin-6, insulin like growth factor-1, biochemical and ultra-structural integrity.
Topics: Animals; Antioxidants; Antitubercular Agents; Cytochrome P-450 CYP2E1; Ethambutol; Insulin-Like Growth Factor I; Interleukin-6; Isoniazid; Liver; Oxidative Stress; Pyrazinamide; Rats; Rats, Wistar; Rifampin | 2023 |
Urinary excretion of metformin in diabetic patients with and without tuberculosis.
Topics: Antitubercular Agents; Diabetes Mellitus; Humans; India; Isoniazid; Metformin; Pyrazinamide; Tuberculosis | 2023 |
Clinical impact of plasma concentrations of first-line antituberculosis drugs.
Topics: Adult; Antitubercular Agents; Humans; Isoniazid; Pyrazinamide; Rifampin; South Africa | 2023 |
The Dysbiosis Triggered by First-Line Tuberculosis Antibiotics Fails to Reduce Their Bioavailability.
Topics: Animals; Antitubercular Agents; Biological Availability; Dysbiosis; Humans; Isoniazid; Mice; Moxifloxacin; Pyrazinamide; Rifampin; Tuberculosis | 2023 |
Acquired drug resistance during the turnaround time for drug susceptibility testing impacts outcome of tuberculosis.
Topics: Antitubercular Agents; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Prospective Studies; Pyrazinamide; Tuberculosis; Tuberculosis, Multidrug-Resistant | 2023 |
Anti-tubercular therapy (ATT) induced exfoliative dermatitis-A case series.
Topics: Antitubercular Agents; Dermatitis, Exfoliative; Humans; Isoniazid; Pyrazinamide; Tuberculosis | 2023 |
Molecular and cellular remodeling of HepG2 cells upon treatment with antitubercular drugs.
Topics: Antitubercular Agents; Chemical and Drug Induced Liver Injury; Hep G2 Cells; Humans; Isoniazid; Pyrazinamide; Tuberculosis | 2023 |
A physiologically-based pharmacokinetic model for tuberculosis drug disposition at extrapulmonary sites.
Topics: Antitubercular Agents; Ethambutol; Humans; Isoniazid; Pyrazinamide; Rifampin; Tuberculosis | 2023 |
Near-infrared molecular sensor for visualizing and tracking ONOO
Topics: Animals; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Fluorescent Dyes; HeLa Cells; Humans; Isoniazid; Mice; Peroxynitrous Acid; Pyrazinamide; Zebrafish | 2023 |
Protein binding investigation of first-line and second-line antituberculosis drugs.
Topics: Antitubercular Agents; Ethambutol; Humans; Isoniazid; Levofloxacin; Linezolid; Moxifloxacin; Protein Binding; Pyrazinamide; Rifampin; Tuberculosis | 2023 |
Antimicrobial drug resistant features of Mycobacterium tuberculosis associated with treatment failure.
Topics: Amikacin; Antitubercular Agents; Humans; Isoniazid; Linezolid; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Tuberculosis, Multidrug-Resistant; Verapamil | 2023 |
Evaluating pediatric tuberculosis dosing guidelines: A model-based individual data pooled analysis.
Topics: Adolescent; Adult; Antitubercular Agents; Child; Child, Preschool; Female; HIV; HIV Infections; Humans; Infant; Infant, Newborn; Isoniazid; Lopinavir; Male; Pyrazinamide; Rifampin; Ritonavir; Tuberculosis | 2023 |
Effect of HIV infection on plasma exposure to first-line TB drugs and target attainment in children.
Topics: Antitubercular Agents; Child; Child, Preschool; Coinfection; HIV Infections; Humans; Isoniazid; Pyrazinamide; Tuberculosis | 2023 |
Atypical Morphology of a Typical Mycobacterial Infection.
Topics: Antitubercular Agents; Ethambutol; Female; Humans; Isoniazid; Pyrazinamide; Skin Neoplasms | 2023 |