putrescine and sulindac

putrescine has been researched along with sulindac in 4 studies

Research

Studies (4)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	3 (75.00)	29.6817
2010's	1 (25.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Hughes, A; Smith, NI; Wallace, HM	1
Babbar, N; Casero, RA; Gerner, EW; Ignatenko, NA	1
Besselsen, DG; Blohm-Mangone, KA; Gerner, EW; Guillen-R, JM; Ignatenko, NA; Padilla-Torres, JL; Roy, UK; Stringer, DE	1
Chen, WP; Gerner, EW; LaFleur, BJ; McLaren, CE; Meyskens, FL; Thompson, PA; Wertheim, BC; Zell, JA	1

Trials

1 trial(s) available for putrescine and sulindac

Article	Year
Levels of rectal mucosal polyamines and prostaglandin E2 predict ability of DFMO and sulindac to prevent colorectal adenoma. Gastroenterology, 2010, Volume: 139, Issue:3 Topics: Adenoma; Aged; Anticarcinogenic Agents; Biomarkers, Pharmacological; Biopsy; Colonoscopy; Colorectal Neoplasms; Dinoprostone; Double-Blind Method; Drug Therapy, Combination; Eflornithine; Enzyme Inhibitors; Female; Humans; Intestinal Mucosa; Likelihood Functions; Logistic Models; Male; Middle Aged; Neoplasms, Second Primary; Polyamines; Putrescine; Rectum; Spermidine; Spermine; Sulindac; Time Factors; Treatment Outcome	2010

Article

Year

Levels of rectal mucosal polyamines and prostaglandin E2 predict ability of DFMO and sulindac to prevent colorectal adenoma.

Gastroenterology, 2010, Volume: 139, Issue:3

Topics: Adenoma; Aged; Anticarcinogenic Agents; Biomarkers, Pharmacological; Biopsy; Colonoscopy; Colorectal Neoplasms; Dinoprostone; Double-Blind Method; Drug Therapy, Combination; Eflornithine; Enzyme Inhibitors; Female; Humans; Intestinal Mucosa; Likelihood Functions; Logistic Models; Male; Middle Aged; Neoplasms, Second Primary; Polyamines; Putrescine; Rectum; Spermidine; Spermine; Sulindac; Time Factors; Treatment Outcome

2010

Other Studies

3 other study(ies) available for putrescine and sulindac

Article	Year
Polyamines reverse non-steroidal anti-inflammatory drug-induced toxicity in human colorectal cancer cells. The Biochemical journal, 2003, Sep-01, Volume: 374, Issue:Pt 2 Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cell Division; Cell Membrane; Cell Survival; Colorectal Neoplasms; DNA Fragmentation; Dose-Response Relationship, Drug; Fluorescent Dyes; Humans; Indoles; Intercalating Agents; Naproxen; Polyamines; Putrescine; Salicylates; Spermidine; Spermine; Sulindac; Tumor Cells, Cultured	2003
Cyclooxygenase-independent induction of apoptosis by sulindac sulfone is mediated by polyamines in colon cancer. The Journal of biological chemistry, 2003, Nov-28, Volume: 278, Issue:48 Topics: Acetyltransferases; Apoptosis; Blotting, Northern; Blotting, Western; Caco-2 Cells; Cell Membrane; Cell Survival; Colonic Neoplasms; Cyclooxygenase 2; DNA, Complementary; Dose-Response Relationship, Drug; Humans; Immunoblotting; Isoenzymes; Membrane Proteins; Models, Biological; Models, Genetic; Oligonucleotide Array Sequence Analysis; Oligonucleotides; Plasmids; Polyamines; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Protein Binding; Protein Biosynthesis; Putrescine; Receptors, Cytoplasmic and Nuclear; Response Elements; RNA; Spermidine; Sulindac; Time Factors; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transfection	2003
Dietary putrescine reduces the intestinal anticarcinogenic activity of sulindac in a murine model of familial adenomatous polyposis. Nutrition and cancer, 2006, Volume: 56, Issue:2 Topics: Adenomatous Polyposis Coli; Adenosylmethionine Decarboxylase; Animals; Antineoplastic Agents; Cyclooxygenase Inhibitors; Diet; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Female; Intestine, Small; Male; Mice; Mice, Inbred C57BL; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Random Allocation; RNA, Messenger; Spermidine; Spermine; Sulindac	2006