putrescine and sulindac

putrescine has been researched along with sulindac in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (75.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hughes, A; Smith, NI; Wallace, HM1
Babbar, N; Casero, RA; Gerner, EW; Ignatenko, NA1
Besselsen, DG; Blohm-Mangone, KA; Gerner, EW; Guillen-R, JM; Ignatenko, NA; Padilla-Torres, JL; Roy, UK; Stringer, DE1
Chen, WP; Gerner, EW; LaFleur, BJ; McLaren, CE; Meyskens, FL; Thompson, PA; Wertheim, BC; Zell, JA1

Trials

1 trial(s) available for putrescine and sulindac

ArticleYear
Levels of rectal mucosal polyamines and prostaglandin E2 predict ability of DFMO and sulindac to prevent colorectal adenoma.
    Gastroenterology, 2010, Volume: 139, Issue:3

    Topics: Adenoma; Aged; Anticarcinogenic Agents; Biomarkers, Pharmacological; Biopsy; Colonoscopy; Colorectal Neoplasms; Dinoprostone; Double-Blind Method; Drug Therapy, Combination; Eflornithine; Enzyme Inhibitors; Female; Humans; Intestinal Mucosa; Likelihood Functions; Logistic Models; Male; Middle Aged; Neoplasms, Second Primary; Polyamines; Putrescine; Rectum; Spermidine; Spermine; Sulindac; Time Factors; Treatment Outcome

2010

Other Studies

3 other study(ies) available for putrescine and sulindac

ArticleYear
Polyamines reverse non-steroidal anti-inflammatory drug-induced toxicity in human colorectal cancer cells.
    The Biochemical journal, 2003, Sep-01, Volume: 374, Issue:Pt 2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cell Division; Cell Membrane; Cell Survival; Colorectal Neoplasms; DNA Fragmentation; Dose-Response Relationship, Drug; Fluorescent Dyes; Humans; Indoles; Intercalating Agents; Naproxen; Polyamines; Putrescine; Salicylates; Spermidine; Spermine; Sulindac; Tumor Cells, Cultured

2003
Cyclooxygenase-independent induction of apoptosis by sulindac sulfone is mediated by polyamines in colon cancer.
    The Journal of biological chemistry, 2003, Nov-28, Volume: 278, Issue:48

    Topics: Acetyltransferases; Apoptosis; Blotting, Northern; Blotting, Western; Caco-2 Cells; Cell Membrane; Cell Survival; Colonic Neoplasms; Cyclooxygenase 2; DNA, Complementary; Dose-Response Relationship, Drug; Humans; Immunoblotting; Isoenzymes; Membrane Proteins; Models, Biological; Models, Genetic; Oligonucleotide Array Sequence Analysis; Oligonucleotides; Plasmids; Polyamines; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Protein Binding; Protein Biosynthesis; Putrescine; Receptors, Cytoplasmic and Nuclear; Response Elements; RNA; Spermidine; Sulindac; Time Factors; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transfection

2003
Dietary putrescine reduces the intestinal anticarcinogenic activity of sulindac in a murine model of familial adenomatous polyposis.
    Nutrition and cancer, 2006, Volume: 56, Issue:2

    Topics: Adenomatous Polyposis Coli; Adenosylmethionine Decarboxylase; Animals; Antineoplastic Agents; Cyclooxygenase Inhibitors; Diet; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Female; Intestine, Small; Male; Mice; Mice, Inbred C57BL; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Random Allocation; RNA, Messenger; Spermidine; Spermine; Sulindac

2006