purine has been researched along with pyrimidine in 303 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 126 (41.58) | 18.7374 |
| 1990's | 35 (11.55) | 18.2507 |
| 2000's | 69 (22.77) | 29.6817 |
| 2010's | 55 (18.15) | 24.3611 |
| 2020's | 18 (5.94) | 2.80 |
| Authors | Studies |
|---|---|
| Nakamura, T; Ueda, T | 1 |
| Heinmets, F; Leary, RH | 1 |
| Demers, GW; Hardison, RC; Margot, JB | 1 |
| Adey, NB; Burton, FH; Casavant, NC; Cole, P; Davies, CJ; Loeb, DD; McGraw, RA; Schichman, SA; Severynse, DM; Shehee, WR | 1 |
| Holmes, GE; Holmes, NR | 1 |
| Nussinov, R | 1 |
| Holmes, EW; Meade, JC; Thomas, CB | 1 |
| Chang, HL; Chen, GZ; Huang, ZY | 1 |
| Bökkerink, JP; De Abreu, RA; De Bruyn, CH; De Vaan, GA; Lippens, RJ; Schouten, TJ; Van Laarhoven, JP | 1 |
| de Souza, LR; Moore, H; Raha, S; Reed, JK | 1 |
| Matsuda, A; Ono, A | 1 |
| Borisova, OF; Florentiev, VL; Il'icheva, IA; Khomyakova, EB; Minyat, EE; Shchyolkina, AK; Timofeev, EN | 1 |
| Abe, K; Saitoh, Y; Usami, M; Wang, J; Yasuda, I; Yumisashi, T | 1 |
| Yagil, G | 1 |
| Hiroshige, K; Kuroiwa, A; Takasugi, M; Yuu, K | 1 |
| Chuprina, VP; Nerdal, W; Poltev, VI; Sletten, E | 1 |
| Hansen, LF; Jacobsen, JP; Jensen, LK | 1 |
| Gao, X; Hogan, ME; Ji, J | 1 |
| Arnold, L; Chládková, J; Kypr, J; Sági, J; Szemzö, A; Vorlícková, M | 1 |
| Kypr, J; Sági, J; Szakonyi, E; Vorlícková, M | 1 |
| Ketterling, RP; Sommer, SS | 1 |
| Agrawal, S; Kandimalla, ER; Manning, A | 1 |
| Downs, DM; Zilles, JL | 1 |
| Kato, M | 1 |
| Blume, SW; Guarcello, V; Miller, DM; Zacharias, W | 1 |
| Barclay, LR; Crowe, E; Edwards, CD | 1 |
| Duley, JA; Fairbanks, LD; McBride, MB; Simmonds, HA | 1 |
| Allers, P; Berger, R; Dorland, L; Duran, M; Meuleman, EE | 1 |
| Fiszer-Kierzkowska, A; Krawczyk, Z; Lisowska, K; Loch, T; Scieglińska, D | 1 |
| Clegg, MT; Morton, BR; Oberholzer, VM | 1 |
| Altmann, KH; Freier, SM | 1 |
| Amano, N; Ohfuku, Y; Suzuki, M | 1 |
| Zastawny, TH | 1 |
| Burda, JV; Doody, AM; Hobza, P; Leszczynski, J; Sabat, M; Sponer, J | 1 |
| Cappiello, M; Giorgelli, F; Ipata, PL; Mascia, L; Scolozzi, C | 1 |
| Haworth, IS; Shamma, T | 1 |
| Avil s, FX; Azorín, F; Canals, F; García-Bassets, I; Ortiz-Lombardía, M; Pagans, S; Romero, A | 1 |
| Kominami, R; Mishima, Y | 1 |
| Ikemura, T; Ohno, M | 1 |
| Akeson, M; Deamer, DW | 1 |
| Bertrand, JR; Gottikh, MB; Maksimenko, AV; Malvy, C; Porumb, H; Shabarova, ZA; Volkov, EM | 1 |
| Bogár, L; Gál, J; Riedel, BJ; Róth, E; Royston, D; Tekeres, M | 1 |
| Brightwell, G; Drewe, LJ; Hall, EA | 1 |
| Pohanka, E | 1 |
| Craig, NL; Rao, JE | 1 |
| Knops, J; Miller, DM; Potaman, V; Thayaparan, J; Trent, J; Vigneswaran, N; Zacharias, W | 1 |
| Gouyette, C; Hantz, E; Huynh Dinh, T; Ladam, P; Larue, V; Le Moyec, L | 1 |
| Landfear, SM | 1 |
| Ihara, T; Jyo, A; Takeda, Y | 1 |
| Chothia, C; Gough, J; Riley, M; Rison, SC; Teichmann, SA; Thornton, JM | 1 |
| Bergerat, JP; Cazenave, JP; Céraline, J; Deplanque, G; Klein-Soyer, C; Mah-Becherel, MC | 1 |
| Van den Berghe, G | 1 |
| Aoki, T; Nara, T | 1 |
| Adam, T; Friedecký, D; Lochman, P | 1 |
| Hokabe, S; Kato, M; Lyubchenko, YL; McAllister, CJ; Shimizu, N | 1 |
| Davis, AE; Mulligan, A; Prada, AE; Prada, JA; Zahedi, K | 1 |
| Bloom, LB; Jaiswal, AS; Narayan, S | 1 |
| Gel'fand, MS; Mironov, AA; Rakhmaninova, AB; Ravcheev, DA | 1 |
| Allen, S; Downs, DM; Zilles, JL | 1 |
| Hall, KB; Jean, JM | 1 |
| Chen, YH; Huang, XL; Li, LQ; Zhang, HY | 1 |
| Alekseev, Y; Bertrand, JR; Gottikh, MB; Ivanov, S; Malvy, C | 1 |
| BORTNER, HW; FAIRLEY, JL; LORING, HS; SEAGRAN, HL | 1 |
| FAIRLEY, JL; LORING, HS; SEAGRAN, HL | 1 |
| CHRISTMAN, AA | 1 |
| WYATT, GR | 2 |
| RUFFILLI, D | 1 |
| FRIEDMAN, S; GOTS, JS | 1 |
| FRIEDKIN, M | 1 |
| DIMROTH, K; MEYER-BRUNOT, HG | 1 |
| WOODHOUSE, DL | 1 |
| BOLTON, ET; REYNARD, AM | 1 |
| SHERRATT, HS; THOMAS, AJ | 2 |
| AGARWALA, SC; MURTI, CR; SHRIVASTAVA, DL | 1 |
| HERSHEY, AD | 1 |
| COOPER, WD; LORING, HS | 1 |
| MASAMUNE, H; SAKAMOTO, M | 1 |
| OTTEY, L | 1 |
| EBNER, H; SCHNEIDER, W | 1 |
| FRICK, G | 1 |
| BERNE, RM; WOLF, MM | 1 |
| BARBU, E; LEE, KY | 1 |
| JONSSON, S; NAKAMURA, M | 1 |
| HARTMAN, RE; RABIN, R; ZIMMERMAN, LN | 1 |
| BROWN, EM; SCHEIN, AH | 1 |
| PREZIOSI, P | 1 |
| DAVIDSON, JN; KEIR, HM | 1 |
| HURST, RO; KUKSIS, A | 1 |
| COOK, MH; GREENE, EA; LORBER, V | 1 |
| HITCHINGS, GH | 1 |
| AGROSKII, LS; EVREINOVA, TN; KOROLEV, NV | 1 |
| COHEN, SS; LOEB, MR | 1 |
| CHEVALLIER, MR; LUZZATI, D; SHCWEITZ, H | 1 |
| BEHAL, FJ; EAKIN, RE | 1 |
| FEO, F; JACOB, M; MANDEL, P; QUIRIN, C | 1 |
| GERRITSMA, KW; LEVIUS, HP | 1 |
| BROWN, BJ; GOLDSTEIN, A; GOLDSTEIN, DB | 1 |
| GOODWIN, TW; PASSORN, PN | 1 |
| GREENLEES, J; GROSSMAN, L | 1 |
| HENDERSON, JF; JUNGA, IG | 1 |
| DUERRE, JA; LICHSTEIN, HC | 1 |
| EDSTROM, JE | 1 |
| KAPLAN, HS; SMITH, KC; TOMLIN, P | 1 |
| COZETTE, J; DEYSSON, G; THOMAS, JA | 1 |
| ADAMS, WS; DAVIS, F; NAKATANI, M | 1 |
| CALDARERA, CM; INFANTE, R; RABBI, A | 1 |
| DOUDNEY, CO; HAAS, FL | 1 |
| DAVIES, GH; FRISCH, AW | 1 |
| TIMMIS, GM | 1 |
| HANSBURY, E; WILLIAMS, DL | 1 |
| PULLMAN, A; PULLMAN, B | 2 |
| MATKHANOV, GI; SUKHORUKOV, BI | 1 |
| DAINKO, JL; SCHLENK, F; SVIHLA, G | 1 |
| WEIMAR, V | 1 |
| ABRAHAM, KA; BHARGAVA, PM | 1 |
| BUTZEL, HM; VAN WAGTENDONK, WJ | 1 |
| CARMINATI, GM | 1 |
| JEFFREY, JJ; SCHANKER, LS; TOCCO, DJ | 1 |
| BROWN, EG | 1 |
| HABERMANN, V | 1 |
| GUT, J | 1 |
| BERTHOD, H; PULLMAN, A | 2 |
| CERHOVA, M; HABERMANN, V; HABERMANNOVA, S | 1 |
| KEMPNER, ES; MILLER, JH | 1 |
| MESNARD, G; VASILESCU, D | 1 |
| NIKIFOROVA, GS | 1 |
| MANDEL, HG; ZIMMERMAN, EF | 2 |
| FEDOROV, NA; KASATKIN, IN | 1 |
| HU, PC; LIANG, CC; LIU, CP; WU, H | 1 |
| BEISER, SM; ERLANGER, BF; ROSENKRANZ, HS; TANENBAUM, SW | 1 |
| BURNS, VW | 2 |
| TARR, HL | 1 |
| FAGUET, M | 1 |
| LIN, JK; TUNG, TC | 1 |
| BEISER, SM; ERLANGER, BF; TANENBAUM, SW | 1 |
| CAPPUCCINO, JG; GEORGE, M; MERKER, PC; TARNOWSKI, GS | 1 |
| Earle, JD; Howsden, FL; Kaplan, HS | 1 |
| MOYED, HS | 1 |
| ITZHAKI, S | 1 |
| PULLMAN, B | 1 |
| HALL, AP; HOLLOWAY, VP; SCOTT, JT | 1 |
| JOHNSON, RC; ROGERS, P | 1 |
| HATFIELD, D; WYNGAARDEN, JB | 1 |
| CAILLET, J; CLAVERIE, P; PULLMAN, B | 1 |
| LANGEN, P | 1 |
| WEETALL, HH; WELIKY, N | 1 |
| BLOOM, SM; BOROWITZ, IJ; ROTHSCHILD, J; SPRINSON, DB | 1 |
| DEWEY, VC; KIDDER, GW | 1 |
| AGARWALA, SC; MISRA, J; SHRIVASTAVA, DL | 1 |
| LODDO, B | 1 |
| LATA, GF; MOLINARI, G | 1 |
| MYER, YP; SCHELLMAN, JA | 1 |
| NESTER, EW; SPIZIZEN, J | 1 |
| Blanca, G; Hübscher, U; Maga, G; Ramadan, K; Shevelev, I; Spadari, S; Villani, G | 1 |
| Charlier, D; Devroede, N; Gigot, D; Maes, D; Thia-Toong, TL | 1 |
| MARSHAK, A | 2 |
| MARTINEZ, C | 1 |
| GRIFFIN, AC; RHEIN, A | 1 |
| EL'PINER, IE; KATS, TB | 1 |
| HOFFMANN, HA; PAVCEK, PL | 1 |
| MACNUTT, WS | 1 |
| BIEBER, S; HITCHINGS, GH; NIGRELLI, RF | 1 |
| MANTEGAZZA, P; MIHICH, E; TOMMASINI, R | 1 |
| POMPER, S | 1 |
| DOWNING, M; ROSE, IA; SCHWEIGERT, BS | 1 |
| Kim, K; Weiss, LM | 1 |
| Cortacero-Ramírez, S; Cruces-Blanco, C; Fernández-Gutiérrez, A; Hernáinz-Bermúdez de Castro, M; Segura-Carretero, A | 1 |
| MARKHAM, R; SMITH, JD | 1 |
| BARKER, GR; DHAR, MM; PARSONS, LD | 1 |
| SAUBERLICH, HE | 1 |
| ALLFREY, VG; DALY, MM; MIRSKY, AE | 1 |
| DEWEY, VC; HEINRICH, MR; KIDDER, GW; PARKS, RE | 1 |
| Hoffmann, C; Jacobson, KA; Soltysiak, K; West, PL | 1 |
| Chattopadhayaya, J; Eriksson, S; Földesi, A; Maltseva, T; Usova, E | 1 |
| Balzarini, J; De Clercq, E; Gazivoda, T; Kralj, M; Kraljević, S; Mintas, M; Pavelić, K; Plavec, J; Plevnik, M; Raić-Malić, S | 1 |
| Matyska, MT; Pesek, JJ | 1 |
| Cunniffe, S; Lomax, ME; O'Neill, P; Salje, H | 1 |
| Kannan, S | 1 |
| Chen, FX; Gold, B; Li, JS; Marky, LA; Shikiya, R | 1 |
| Bradshaw, PC; Rathi, A; Samuels, DC | 1 |
| Baglioni, P; Berti, D; Bombelli, FB; Dante, S; Hauss, T; Milani, S | 1 |
| Nielsen, PE; Sen, A | 1 |
| Peng, X; Seela, F | 1 |
| Al-Hashimi, HM; Hansen, AL | 1 |
| Peters, GJ; Sigmond, J | 1 |
| Binnewies, TT; Bohlin, J; Champ, PC; Kiil, K; Nielsen, N; Ussery, DW; Wu, H; Zinman, G | 1 |
| Kalra, N; Parlato, MC; Parmar, VS; Wengel, J | 1 |
| Aldern, KA; Beadle, JR; Hostetler, KY; Trahan, J; Valiaeva, N | 1 |
| Batey, RT; Gilbert, SD; Stoddard, CD; Wise, SJ | 1 |
| Bagshaw, AT; Gemmell, NJ; Pitt, JP | 1 |
| Baeyens, WR; Delanghe, JR; Ouyang, J; Shen, X; Xiong, X; Yang, Y | 1 |
| Casetta, B; Donati, MA; Innocenti, M; la Marca, G; Malvagia, S; Pasquini, E; Zammarchi, E | 1 |
| Batey, RT; Gilbert, SD; Mediatore, SJ | 1 |
| Beyhan, S; Lim, B; Yildiz, FH | 1 |
| Bell, SE; Sirimuthu, NM | 1 |
| Bellofatto, V | 1 |
| Burnstock, G | 1 |
| Arenas, M; Barker, JN; Campalani, E; Lewis, CM; Marinaki, AM; Smith, CH | 1 |
| Drabczyńska, A; Karolak-Wojciechowska, J; Kieć-Kononowicz, K; Müller, CE; Schiedel, A; Schumacher, B; Yuzlenko, O | 1 |
| Amira, MF; El-Ashry, GM; Masoud, MS; Ramadan, AM | 1 |
| Arranz, N; Delgado, E; García, A; Haza, AI; Morales, P; Rafter, J | 1 |
| Delcros, JG; Pérez-Flores, L; Ramírez, FJ; Ruiz-Chica, AJ; Sánchez-Jiménez, FM | 1 |
| Cohn, WE | 1 |
| Koyama, S; Miyakoshi, J; Nakahara, T; Sakurai, T | 1 |
| LORING, HS; PIERCE, JG | 2 |
| Morita, K; Nishizawa, S; Sato, Y; Seino, T; Teramae, N | 1 |
| Becker, MA; Sabina, RL | 1 |
| Eriksson, S; Wang, L | 1 |
| Au, LC; Li, WT; Wang, TH; Yu, SH | 1 |
| Campos, JM; Conejo-García, A; Cruz-López, O; Díaz-Gavilán, M; Espinosa, A; Gallo, MA; Núñez, MC | 1 |
| Ivanova, E; Wang, F; Zhu, Q | 1 |
| Barth, K; Volonté, C | 1 |
| Cherian, C; Deng, Y; Gangjee, A; Hou, Z; Kugel Desmoulin, S; Matherly, LH; Wu, J; Zhou, X | 1 |
| Balzarini, J; Bronckaers, A; Liekens, S | 1 |
| Maruhashi, K; Monguchi, Y; Mutsumi, T; Sajiki, H | 1 |
| DAVOLL, J; LYTHGOE, B; TODD, AR | 1 |
| HOWARD, GA; KENNER, GW | 1 |
| Elchinger, PH; Faugeras, PA; Lucas, R; Zerrouki, R | 1 |
| Eriksson, S; Peters, GJ | 1 |
| Alpert, C; Blaut, M; Engst, W; Loh, G; Vogel-Scheel, J | 1 |
| Chen, K; Hu, S; Liu, J; Wang, L; Xin, C; Yang, M; Yu, J | 1 |
| Joshi, PC; Keane, TC | 1 |
| Ashihara, H; Belmonte, M; Elhiti, M; Stasolla, C | 1 |
| Dudley, E; Griffiths, WJ; Wang, Y; Yousef, M | 1 |
| Ghavami, R; Navaee, A; Salimi, A | 1 |
| Blomhoff, R; Brevik, A; Collins, AR; Duttaroy, AK; Elilasson, J; Gaivão, I; Jørgenesen, A; Karlsen, A; Medin, T; Piasek, A; Veggan, T | 1 |
| Batzler, A; Fridley, BL; Jenkins, GD; Ji, Y; Li, F; Li, L; Matimba, A; Wang, L; Weinshilboum, RM | 1 |
| Bulavin, LA; Hovorun, DM; Nikolaienko, TY | 1 |
| Fujimori, S; Inagawa, S; Inazawa, K; Kaneko, K; Mawatari, K; Nakagomi, K; Yamada, Y; Yamaoka, N; Yasuda, M | 1 |
| Bade, K; Gicheru, Y; Hunt, KA; Mansfield, TA; Mourad, GS; Schultes, NP; Tippmann-Crosby, J | 1 |
| Al-Hashimi, HM; Andricioaei, I; Bascom, GD; Nikolova, EN | 1 |
| Ba, X; Chu, Y; Ding, Y; Luo, L; Ouyang, X; Wang, B; Zhang, Z | 1 |
| Hong-Bo, L; Li-Na, Y; Liu, X; Qin, X; Xiaoya, H | 1 |
| Chen, H; Dai, Z; Tian, J; Wang, P; Zou, X | 1 |
| Brovarets', OO; Hovorun, DM | 1 |
| Operschall, BP; Sigel, A; Sigel, H | 1 |
| Cheng, L; Li, K; Li, S; Li, X; Ma, L; Ma, Q | 1 |
| Al-Hashimi, HM; Kimsey, I | 1 |
| Argoud, K; Bihoreau, MT; Caldérari, S; Finlay, C; Gauguier, D; Kaisaki, PJ; Kessler, BM; McGouran, JF; Mott, R; Otto, GW; Toubal, A; Waller-Evans, H | 1 |
| Avasthi, K; Kant, R; Ravikumar, K; Shukla, L | 1 |
| Pathak, AK; Pathak, V; Reynolds, RC | 1 |
| Peters, GJ; Puig, JG; Torres, RJ | 1 |
| Balzarini, J; Camarasa, MJ; de Castro, S; Fernández-Cureses, G; Jimeno, ML | 1 |
| Dong, S; Kuo, MS; Nikolayev, A; Tolstikov, V; Zhao, G | 1 |
| Bradforth, SE; Faubel, M; Jungwirth, P; Pluhařová, E; Schroeder, CA; Schroeder, WP; Seidel, R; Slavíček, P; Winter, B | 1 |
| Ashihara, H; Deng, WW; Katahira, R | 1 |
| Amador-Noguez, D; Jacobson, TB; O'Brien, TJ; Pisithkul, T; Stevenson, DM | 1 |
| Jia, W; Qiu, Y; Wang, J; Xu, Y; Yin, S; Zheng, X | 1 |
| Hajnic, M; Osorio, JI; Zagrovic, B | 1 |
| Downey, AM; Hocek, M; Mahrwald, R; Pohl, R; Richter, C | 1 |
| Hesdorffer, CS; Longo, DL | 1 |
| Brinson, RG; Kahn, JD; Le Grice, SF; Marino, JP; Miller, JT | 1 |
| Markelj, J; Pihlar, B; Zupančič, T | 1 |
| Butenko, A; Flegontov, P; Lukeš, J; Opperdoes, FR; Yurchenko, V | 1 |
| Hayashi, M; Kijima, Y; Tazuya-Murayama, K; Yamada, K | 1 |
| Acosta-Jurado, S; An, Q; Andersen, SU; Gil-Serrano, A; Jin, H; Kawaharada, Y; Perea, JF; Rodríguez-Carvajal, MA; Rodríguez-Navarro, DN; Ruiz-Sainz, JE; Sandal, N; Stougaard, J; Vinardell, JM | 1 |
| Balaceanu, A; Dans, PD; Hospital, A; Lavery, R; Orozco, M; Pasi, M | 1 |
| Guo, F; Huang, Y; Li, J; Li, Y; Wang, J | 1 |
| Bezwada, D; Byers, LA; Cai, L; Castrillon, DH; Chen, BPC; Choi, E; DeBerardinis, RJ; Faubert, B; Girard, L; Heymach, JV; Hu, Z; Huffman, KE; Kim, J; Lambrechts, D; Li, K; Lin, YF; Minna, JD; Ni, M; Peña, CG; Rodriguez-Canales, J; Unsal-Kacmaz, K; Vansteenkiste, J; Villalobos, P; Wauters, E; Wistuba, I; Xu, J | 1 |
| Chan, KM; Kool, ET; Xu, W | 1 |
| Gao, L; Liu, C; Liu, H; Liu, X; Wang, J | 1 |
| Filarsky, M; Grummt, I; Längst, G; Maldonado, R | 1 |
| Besalú-Sala, P; Cavallo, L; Chawla, M; Kalra, K; Oliva, R; Poater, A | 1 |
| Brachman, RA; Denny, CA; Hill, C; Kiebish, MA; Kitayev, A; LaGamma, CT; Mastrodonato, A; McGowan, JC; Narain, NR | 1 |
| Al-Hashimi, HM; Liu, B; Meiser, N; Merriman, DK; Rangadurai, A; Shi, H; Szymanski, ES; Zhou, H | 1 |
| Gautham, N; Karthik, S; Mandal, PK; Thirugnanasambandam, A | 1 |
| Arnold, RS; Clendinen, CS; Edison, AS; Fernández, FM; Gaul, DA; Monge, ME; Petros, JA | 1 |
| Li, J; Wang, H; Xie, L; Yu, L; Zhang, R | 1 |
| de Farias, ST; Marques, LM; Silva, JK; Timenetsky, J | 1 |
| Badiger, MV; Nuthanakanti, A; Srivatsan, SG; Torris, A; Walunj, MB | 1 |
| Cai, Y; Chatterjee, AK; Chen, E; Cubitt, B; de la Torre, JC; Hull, MV; Kim, YJ; Kuhn, JH | 1 |
| Hiraoka, W; Iizuka, D; Inanami, O; Kuwabara, M; Matsuda, A; Yasui, H | 1 |
| Herde, M; Witte, CP | 1 |
| Chen, Z; Harris, JM; Heemstra, JM; Lackey, HH; Peterson, EM | 1 |
| Dai, SX; Feng, K; Li, BX; Li, WX; Li, Y; Liu, Y; Sun, M; Zhang, H; Zheng, JJ | 1 |
| Campagnaro, GD; de Koning, HP | 1 |
| Hu, G; Li, H; Wang, J; Xu, S | 1 |
| Jordheim, LP; Peters, GJ | 1 |
| Matsumoto, Y; Niizuma, K; Rashad, S; Saigusa, D; Saito, R; Tominaga, T; Tomioka, Y; Uruno, A; Yamamoto, M; Yamazaki, T | 1 |
| Chasin, LA; Du, Z; Jiang, B; Zhang, Q | 1 |
| Bachelot, A; Funck-Brentano, C; Ichou, F; Leban, M; Nguyen, LS; Prifti, E; Salem, JE; Touraine, P | 1 |
| Duan, J; Fan, S; Li, Y; Liu, H; Shu, L; Wang, Y; Xie, L; Xu, Y; Zhao, Y | 1 |
| Davis, AP; Samanta, SK; Van Eker, D | 1 |
| Alexander, M; Deshpande, I; Nayak, RR; Patterson, AD; Rimal, B; Scher, JU; Stapleton-Gray, K; Turnbaugh, PJ; Ubeda, C | 1 |
| Brunkard, JO; Busche, M; Hnasko, R; Scarpin, MR | 1 |
| Banfalvi, G | 1 |
| Simmons, LA; Wozniak, KJ | 1 |
| Ekins, S; Finkelstein, D; Fukuda, Y; Ganguly, S; Michalek, RD; Mukherjee, K; Schuetz, EG; Schuetz, JD; Shaw, TI; Yasuda, K; Zorn, KM | 1 |
| Al-Salabi, MI; AlSiari, TA; De Koning, HP; Eckmann, L; Eze, AA; Miyamoto, Y; Munday, JC; Natto, MJ; Quashie, NB | 1 |
31 review(s) available for purine and pyrimidine
| Article | Year |
|---|---|
[Synthesis of oligonucleotide analogues by the post-elongation modification methods].
Topics: Animals; DNA; Humans; Methods; Oligonucleotides; Purines; Pyrimidines; RNA | 1995 |
The factor IX gene as a model for analysis of human germline mutations: an update.
Topics: Age Factors; Base Sequence; Factor IX; Founder Effect; Germ-Line Mutation; Hemophilia B; Humans; Molecular Sequence Data; Mosaicism; Mutagenesis; Neoplasms; Nucleic Acid Conformation; Purines; Pyrimidines; Sex Ratio | 1996 |
[Pyrimidine/purine-biased sequences: potential to form DNA triplex and its physiological effects].
Topics: Animals; Base Sequence; DNA-Directed DNA Polymerase; DNA, Superhelical; Genome; Humans; Molecular Sequence Data; Nucleic Acid Conformation; Purines; Pyrimidines; Repetitive Sequences, Nucleic Acid; Transcription, Genetic | 1996 |
When to investigate for purine and pyrimidine disorders. Introduction and review of clinical and laboratory indications.
Topics: Biomarkers; Humans; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Pyrimidines | 1997 |
Inherited defects of purine and pyrimidine metabolism: laboratory methods for diagnosis.
Topics: Animals; Artifacts; Chromatography; Humans; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Pyrimidines; Uric Acid | 1997 |
Genomes and DNA conformation.
Topics: DNA; Genome; Nucleic Acid Conformation; Purines; Pyrimidines | 1997 |
[DNA oxidative damages--free radical modification of bases and sugar moieties].
Topics: Adenine; Anaerobiosis; Carbohydrate Metabolism; Cytosine; DNA; Free Radicals; Guanine; Hydroxyl Radical; Mutagenesis; Oxidation-Reduction; Purines; Pyrimidines | 1997 |
[Function of polypurine/polypyrimidine sequences in chromosomes].
Topics: Animals; Chromosomes; DNA; Nucleosomes; Purines; Pyrimidines; Trinucleotide Repeats | 1999 |
[Triplex DNA in human interphase nuclei and its function].
Topics: Cell Nucleus; Centromere; Chromosome Banding; DNA; Humans; Interphase; Purines; Pyrimidines | 1999 |
Nanopores and nucleic acids: prospects for ultrarapid sequencing.
Topics: Bacterial Toxins; Forecasting; Hemolysin Proteins; Nucleic Acids; Purines; Pyrimidines; RNA; Sequence Analysis; Sequence Analysis, DNA | 2000 |
New immunosuppressive drugs: an update.
Topics: Adrenal Cortex Hormones; Alkylating Agents; Calcineurin Inhibitors; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Kidney Transplantation; Propylene Glycols; Purines; Pyrimidines; Sirolimus; Sphingosine; Vitamin D | 2001 |
Molecular genetics of nucleoside transporters in Leishmania and African trypanosomes.
Topics: Africa; Animals; Carrier Proteins; Cloning, Molecular; Leishmania donovani; Membrane Proteins; Nucleoside Transport Proteins; Nucleosides; Purines; Pyrimidines; Trypanosoma brucei brucei | 2001 |
Purine and pyrimidine metabolism between millennia: what has been accomplished, what has to be done?
Topics: Animals; Humans; Purines; Pyrimidines | 2000 |
[The pyrimidine-biosynthetic (pyr) gene cluster in trypanosomes].
Topics: Animals; Aspartate Carbamoyltransferase; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Dihydroorotase; Dihydroorotate Dehydrogenase; Genes, Protozoan; Humans; Multigene Family; Orotate Phosphoribosyltransferase; Orotidine-5'-Phosphate Decarboxylase; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Purines; Pyrimidines; Trypanosoma | 2002 |
AZA ANALOGS OF PYRIMIDINE AND PURINE BASES OF NUCLEIC ACIDS.
Topics: Chemistry, Pharmaceutical; Nucleic Acids; Organic Chemicals; Purines; Pyrimidines; Research; Triazines | 1963 |
[EFFECTS OF ANALOGUES OF PURINE AND PYRIMIDINE BASES ON PHYTOPATHOGENIC VIRUSES].
Topics: Alkalies; Plant Viruses; Purines; Pyrimidines; Research; Viruses | 1963 |
Toxoplasma gondii: the model apicomplexan.
Topics: Animals; Antiprotozoal Agents; Genes, Protozoan; Models, Biological; Purines; Pyrimidines; Toxoplasma | 2004 |
Pyrimidine and purine analogues, effects on cell cycle regulation and the role of cell cycle inhibitors to enhance their cytotoxicity.
Topics: Animals; Cell Cycle; Cyclin-Dependent Kinases; Drug Evaluation; Humans; Purines; Pyrimidines | 2005 |
Pyrimidine transport activities in trypanosomes.
Topics: Animals; Biological Transport; Mutation; Nucleobase Transport Proteins; Nucleoside Transport Proteins; Protozoan Proteins; Purines; Pyrimidines; Trypanosoma; Trypanosoma brucei brucei | 2007 |
Purine and pyrimidine receptors.
Topics: Adenosine Triphosphate; Animals; Dimerization; Gene Expression Regulation; Humans; Purinergic P1 Receptor Agonists; Purinergic P2 Receptor Agonists; Purines; Pyrimidines; Receptors, Purinergic P1; Receptors, Purinergic P2; Transcriptional Activation | 2007 |
Molecular mechanisms of mitochondrial DNA depletion diseases caused by deficiencies in enzymes in purine and pyrimidine metabolism.
Topics: Animals; DNA, Mitochondrial; Enzymes; Humans; Mitochondrial Diseases; Nucleic Acid Precursors; Purines; Pyrimidines | 2008 |
Design, synthesis and anticancer activity against the MCF-7 cell line of benzo-fused 1,4-dihetero seven- and six-membered tethered pyrimidines and purines.
Topics: Acetals; Antineoplastic Agents; Benzene Derivatives; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Drug Design; Fluorouracil; Heterocyclic Compounds; Humans; Inhibitory Concentration 50; Neoplasm Metastasis; Purines; Pyrimidines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Targeted metabolomics and mass spectrometry.
Topics: Humans; Lipid Metabolism; Mass Spectrometry; Metabolism; Metabolomics; Nucleic Acids; Peptides; Plant Preparations; Purines; Pyrimidines; Systems Biology; Volatile Organic Compounds | 2010 |
Comparison of the π-stacking properties of purine versus pyrimidine residues. Some generalizations regarding selectivity.
Topics: Nucleic Acids; Organometallic Compounds; Purines; Pyrimidines | 2014 |
Increasing occurrences and functional roles for high energy purine-pyrimidine base-pairs in nucleic acids.
Topics: Animals; Base Pairing; DNA; Humans; Isomerism; Models, Molecular; Nucleic Acid Conformation; Purines; Pyrimidines | 2014 |
Drug-Induced Megaloblastic Anemia.
Topics: Anemia, Megaloblastic; DNA; Folic Acid; Gastrointestinal Absorption; Humans; Purines; Pyrimidines; Thymine Nucleotides; Vitamin B 12; Vitamin B 12 Deficiency | 2015 |
Comparative Metabolism of Free-living Bodo saltans and Parasitic Trypanosomatids.
Topics: Amino Acids; Bacteria; Carbohydrate Metabolism; Coenzymes; Dolichols; Ergosterol; Eukaryota; Folic Acid; Genes, Protozoan; Gluconeogenesis; Glycolysis; Kinetoplastida; Lipid Metabolism; Mevalonic Acid; Microbodies; Mitochondria; Oxidoreductases; Pentose Phosphate Pathway; Peroxisomes; Phospholipids; Polyamines; Protein Prenylation; Protozoan Proteins; Purines; Pyrimidines; Reactive Oxygen Species; Trypanosomatina; Ubiquinone; Urea; Vitamins | 2016 |
Fluorescent nucleobases as tools for studying DNA and RNA.
Topics: DNA; Fluorescent Dyes; Purines; Pyrimidines; RNA | 2017 |
Nucleoside analogs as a radiosensitizer modulating DNA repair, cell cycle checkpoints, and apoptosis.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Disease Models, Animal; DNA Damage; DNA Repair; Humans; Molecular Structure; Nucleosides; Purines; Pyrimidines; Radiation-Sensitizing Agents; Radiation, Ionizing; Radiotherapy; Xenograft Model Antitumor Assays | 2020 |
Purine and pyrimidine transporters of pathogenic protozoa - conduits for therapeutic agents.
Topics: Animals; Protozoan Proteins; Purines; Pyrimidines | 2020 |
Prebiotic Pathway from Ribose to RNA Formation.
Topics: Metabolic Networks and Pathways; Nucleotides; Phosphorylation; Polymerization; Purines; Pyrimidines; Ribose; RNA | 2021 |
1 trial(s) available for purine and pyrimidine
| Article | Year |
|---|---|
Supplementation of a western diet with golden kiwifruits (Actinidia chinensis var.'Hort 16A':) effects on biomarkers of oxidation damage and antioxidant protection.
Topics: Actinidia; Adult; Antioxidants; Ascorbic Acid; Biomarkers; Carotenoids; Comet Assay; Cross-Over Studies; Diet; Dietary Supplements; DNA Damage; DNA Repair; Female; Fruit; Humans; Hydrogen Peroxide; Lipid Metabolism; Lymphocytes; Male; Malondialdehyde; Middle Aged; Oxidative Stress; Platelet Aggregation; Purines; Pyrimidines; Triglycerides; Young Adult | 2011 |
271 other study(ies) available for purine and pyrimidine
| Article | Year |
|---|---|
[Mechanism of action of anti-leukemia agents and adverse effects].
Topics: Antineoplastic Agents; Bone Marrow Cells; Depression, Chemical; DNA, Neoplasm; Folic Acid Antagonists; Hematopoiesis; Humans; Leukemia; Nucleotides; Purines; Pyrimidines | 1992 |
A study of deoxyribonucleotide metabolism and its relation to DNA synthesis. Supercomputer simulation and model-system analysis.
Topics: Animals; Computer Simulation; Deoxyribonucleotides; DNA; Humans; Models, Biological; Purines; Pyrimidines | 1991 |
Complete nucleotide sequence of the rabbit beta-like globin gene cluster. Analysis of intergenic sequences and comparison with the human beta-like globin gene cluster.
Topics: Animals; Base Composition; Base Sequence; DNA; Globins; Humans; Molecular Sequence Data; Multigene Family; Purine Nucleotides; Purines; Pyrimidine Nucleotides; Pyrimidines; Rabbits; Repetitive Sequences, Nucleic Acid; Restriction Mapping; Sequence Homology, Nucleic Acid | 1989 |
Nucleotide sequence of the BALB/c mouse beta-globin complex.
Topics: Animals; Base Sequence; Globins; Humans; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Multigene Family; Purine Nucleotides; Purines; Pyrimidine Nucleotides; Pyrimidines; Repetitive Sequences, Nucleic Acid; Sequence Homology, Nucleic Acid | 1989 |
Purine and pyrimidine metabolism in man V. Part A: Clinical aspects including molecular genetics. Festschrift for J.E. Seegmiller.
Topics: Biochemistry; History, 20th Century; Humans; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Pyrimidines | 1986 |
Accumulation of DNA fragments in aging Paramecium tetraurelia in axenic and nonaxenic media.
Topics: Carbon Radioisotopes; Culture Media; DNA Repair; DNA Replication; DNA, Single-Stranded; Germ-Free Life; Paramecium; Purines; Pyrimidines; Thymidine; Time Factors | 1986 |
Asymmetry in the distributions of the four nucleotides at mRNA initiation and 3' termini sites: some geometrical implications.
Topics: Animals; Base Sequence; Purines; Pyrimidines; RNA, Messenger; Terminator Regions, Genetic; Transcription, Genetic; Vertebrates | 1987 |
Aminoimidazole carboxamide ribonucleoside toxicity: a model for study of pyrimidine starvation.
Topics: Aminoimidazole Carboxamide; Animals; Cell Division; Cell Line; Cricetinae; Cricetulus; Fibroblasts; Imidazoles; Lung; Models, Biological; Pentosephosphates; Phosphoribosyl Pyrophosphate; Purines; Pyrimidines; Ribonucleosides | 1981 |
The metabolism of pyrimidine and purine in Schistosoma japonicum.
Topics: Adenosine Triphosphatases; Animals; Female; Ligases; Male; Orotate Phosphoribosyltransferase; Orotidine-5'-Phosphate Decarboxylase; Purine-Nucleoside Phosphorylase; Purines; Pyrimidines; Schistosoma japonicum | 1984 |
[6-Mercaptopurine and methotrexate, rational use in sight after 35 years?].
Topics: Animals; Child; Dogs; Half-Life; Humans; Infusions, Parenteral; Leukemia, Lymphoid; Lymphocytes; Mercaptopurine; Methotrexate; Purines; Pyrimidines | 1984 |
Purine and pyrimidine nucleotides activate distinct signalling pathways in PC12 cells.
Topics: Adenosine Triphosphate; Animals; Calcium; Dopamine; Dose-Response Relationship, Drug; PC12 Cells; Potassium Chloride; Purines; Pyrimidines; Rats; Signal Transduction; Time Factors | 1995 |
Parallel purine-pyrimidine-purine triplex: experimental evidence for existence.
Topics: Base Sequence; DNA; Fluorescent Dyes; Molecular Conformation; Molecular Sequence Data; Molecular Structure; Oligonucleotides; Purines; Pyrimidines; Temperature | 1995 |
[Effect of 5-FU on the utilization of purine and pyrimidine by human gastric cancer cells (KATO III)].
Topics: Cell Division; Culture Media; Drug Interactions; Fluorouracil; Humans; Purines; Pyrimidines; Stomach Neoplasms; Tumor Cells, Cultured | 1995 |
The frequency of oligopurine.oligopyrimidine and other two-base tracts in yeast chromosome III.
Topics: Base Sequence; Chromosome Mapping; Chromosomes, Fungal; Molecular Sequence Data; Oligonucleotides; Purines; Pyrimidines; Saccharomyces cerevisiae | 1994 |
Studies on the purine-pyrimidine metabolism (2)--Effects of sample preparation and diet on the concentrations of oxypurines in blood and urine.
Topics: Chromatography, High Pressure Liquid; Diet; Humans; Hypoxanthine; Hypoxanthines; Male; Pseudouridine; Purines; Pyrimidines; Specimen Handling; Uric Acid; Uridine; Xanthine; Xanthines | 1994 |
Base dependence of B-DNA sugar conformation in solution and in the solid state.
Topics: Base Sequence; Carbohydrate Conformation; Computer Simulation; Crystallography, X-Ray; Deoxyribose; DNA; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Nucleic Acid Conformation; Purines; Pyrimidines | 1993 |
5th Symposium of the European Society for the Study of Purine and Pyrimidine Metabolism in Man. Termoli, Italy, 4-8 October 1995. Abstracts.
Topics: Humans; Purines; Pyrimidines | 1995 |
Bis-intercalation of a homodimeric thiazole orange dye in DNA in symmetrical pyrimidine-pyrimidine-purine-purine oligonucleotides.
Topics: Base Sequence; Benzothiazoles; DNA; Fluorescent Dyes; Molecular Sequence Data; Oligonucleotides; Purines; Pyrimidines; Quinolines; Thiazoles | 1996 |
Solution structure of an antiparallel purine motif triplex containing a T.CG pyrimidine base triple.
Topics: Base Sequence; Binding Sites; Carbohydrate Metabolism; Carbohydrates; DNA; Magnetic Resonance Spectroscopy; Models, Molecular; Nucleic Acid Conformation; Oligonucleotides; Phosphates; Purines; Pyrimidines; Solutions; Trinucleotide Repeats | 1996 |
The unusual X-form DNA in oligodeoxynucleotides: dependence of stability on the base sequence and length.
Topics: Base Sequence; Circular Dichroism; DNA; Models, Molecular; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Purines; Pyrimidines; Structure-Activity Relationship; Temperature | 1996 |
Unusual contribution of 2-aminoadenine to the thermostability of DNA.
Topics: 2-Aminopurine; Absorption; Bacteriophages; Base Composition; Circular Dichroism; Deoxyribonucleotides; DNA; Molecular Structure; Nucleic Acid Conformation; Nucleic Acid Heteroduplexes; Purines; Pyrimidines; Structure-Activity Relationship; Ultraviolet Rays | 1996 |
Single stand targeted triplex formation: physicochemical and biochemical properties of foldback triplexes.
Topics: Binding Sites; Circular Dichroism; Deoxyribonuclease I; DNA; Electrophoresis; Endodeoxyribonucleases; Gene Products, gag; HIV Antigens; Nucleic Acid Conformation; Nucleic Acid Denaturation; Nucleic Acid Heteroduplexes; Oligonucleotides; Purines; Pyrimidines; RNA, Messenger; RNA, Viral; Single-Strand Specific DNA and RNA Endonucleases; Structure-Activity Relationship; Substrate Specificity; Ultraviolet Rays | 1996 |
A novel involvement of the PurG and PurI proteins in thiamine synthesis via the alternative pyrimidine biosynthetic (APB) pathway in Salmonella typhimurium.
Topics: Alleles; Mutagenesis; Purines; Pyrimidines; Salmonella typhimurium; Thiamine | 1996 |
Divalent transition metal cations counteract potassium-induced quadruplex assembly of oligo(dG) sequences.
Topics: Cations, Divalent; Cobalt; Humans; Manganese; Nickel; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Potassium; Purines; Pyrimidines | 1997 |
Photo-initiated peroxidation of lipids in micelles by azaaromatics.
Topics: Antioxidants; Chromans; Free Radicals; Kinetics; Linoleic Acid; Linoleic Acids; Lipid Peroxidation; Micelles; Models, Chemical; Nicotinic Acids; Photochemistry; Purines; Pyridines; Pyrimidines; Quinolines | 1997 |
Identification of a microsatellite region composed of a long homopurine/homopyrimidine tract surrounded by AT-rich sequences upstream of the rat stress-inducible hsp 70.1 gene.
Topics: Animals; Base Sequence; DNA, Satellite; Heat Stress Disorders; HSP70 Heat-Shock Proteins; Molecular Sequence Data; Purines; Pyrimidines; Rats; Sequence Analysis, DNA | 1997 |
9th International/6th European Joint Symposium on Purine and Pyrimidine Metabolism in Man. Austria, 1-7 June 1997. Abstracts.
Topics: Humans; Purines; Pyrimidines | 1997 |
The influence of specific neighboring bases on substitution bias in noncoding regions of the plant chloroplast genome.
Topics: Chloroplasts; Evolution, Molecular; Genes, Plant; Genome, Plant; Models, Genetic; Open Reading Frames; Purines; Pyrimidines | 1997 |
The ups and downs of nucleic acid duplex stability: structure-stability studies on chemically-modified DNA:RNA duplexes.
Topics: DNA; Nucleic Acid Conformation; Nucleic Acid Hybridization; Oligonucleotides, Antisense; Phosphorus; Purines; Pyrimidines; Ribose; RNA, Complementary; Structure-Activity Relationship; Thymine | 1997 |
Proceedings of the joint 9th International/6th European Symposium on Purine and Pyrimidine Metabolism in Man. Gmunden, Austria, June 1-7, 1997.
Topics: Humans; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Pyrimidines | 1998 |
Stabilization of the purine.purine.pyrimidine DNA base triplets by divalent metal cations.
Topics: Base Pairing; Cations, Divalent; DNA; Magnesium; Purines; Pyrimidines; Zinc | 1998 |
In vitro assessment of salvage pathways for pyrimidine bases in rat liver and brain.
Topics: Animals; Brain; Liver; Phosphoribosyl Pyrophosphate; Purine Nucleosides; Purines; Pyrimidines; Rats; Ribosemonophosphates; Time Factors; Tissue Extracts; Uracil Nucleotides; Uridine | 1998 |
Spermine inhibition of the 2,5-diaziridinyl-1,4-benzoquinone (DZQ) crosslinking reaction with DNA duplexes containing poly(purine). poly(pyrimidine) tracts.
Topics: Aziridines; Benzoquinones; Cross-Linking Reagents; DNA; Purines; Pyrimidines; Spermine | 1999 |
The identification of nuclear proteins that bind the homopyrimidine strand of d(GA.TC)n DNA sequences, but not the homopurine strand.
Topics: Amino Acid Sequence; Blotting, Western; DNA; Molecular Sequence Data; Nuclear Proteins; Protein Binding; Purines; Pyrimidines | 1999 |
Targeting of single-stranded DNA and RNA containing adjacent pyrimidine and purine tracts by triple helix formation with circular and clamp oligonucleotides.
Topics: Circular Dichroism; DNA, Single-Stranded; Genetic Techniques; Nucleic Acid Conformation; Oligonucleotides; Purines; Pyrimidines; RNA; Spectrophotometry, Ultraviolet | 2000 |
[Effect of fructose-1,6-diphosphate on myocardial purin and pyrimidin metabolism during coronary artery bypass grafting surgery].
Topics: Adult; Cardiovascular Agents; Case-Control Studies; Coronary Artery Bypass; Fructosediphosphates; Humans; Immunologic Factors; Myocardium; Purines; Pyrimidines; Time Factors; Treatment Outcome | 2000 |
Detection of PCR products using PNA strand invasion.
Topics: Base Sequence; DNA; DNA Probes; Molecular Sequence Data; Peptide Nucleic Acids; Polymerase Chain Reaction; Purines; Pyrimidines | 2000 |
Selective recognition of pyrimidine motif triplexes by a protein encoded by the bacterial transposon Tn7.
Topics: Animals; Bacterial Proteins; Base Sequence; Cross-Linking Reagents; DNA; DNA Transposable Elements; DNA-Binding Proteins; Drosophila melanogaster; Escherichia coli; Escherichia coli Proteins; Ficusin; HeLa Cells; Humans; Mutagenesis, Insertional; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Plasmids; Purines; Pyrimidines; Saccharomyces cerevisiae; Substrate Specificity | 2001 |
Intra- and intermolecular triplex DNA formation in the murine c-myb proto-oncogene promoter are inhibited by mithramycin.
Topics: Animals; Antibodies; Base Sequence; Binding Sites; Cells, Cultured; Distamycins; Electrophoresis, Gel, Two-Dimensional; Humans; Mice; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Nucleic Acid Heteroduplexes; Nucleic Acid Synthesis Inhibitors; Oligodeoxyribonucleotides; Plicamycin; Promoter Regions, Genetic; Proto-Oncogene Mas; Proto-Oncogene Proteins c-myb; Purines; Pyrimidines; Single-Strand Specific DNA and RNA Endonucleases | 2001 |
Solution conformation of an RNA--DNA hybrid duplex containing a pyrimidine RNA strand and a purine DNA strand.
Topics: DNA; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acid Conformation; Nucleic Acid Heteroduplexes; Protons; Purines; Pyrimidines; RNA; Solutions | 2001 |
Metal ion-directed cooperative triple helix formation of glutamic acid--oligonucleotide conjugate.
Topics: Binding Sites; Copper; Glutamic Acid; Metals; Oligonucleotides; Purines; Pyrimidines; Tandem Repeat Sequences; Telomere; Thermodynamics | 2001 |
Small-molecule metabolism: an enzyme mosaic.
Topics: Binding Sites; Coenzymes; Enzymes; Escherichia coli; Evolution, Molecular; Fucose; Nucleosides; Nucleotides; Protein Structure, Tertiary; Purines; Pyrimidines; Pyruvic Acid; Sequence Homology; Substrate Specificity; Tryptophan | 2001 |
Caffeine and the G2/M block override: a concept resulting from a misleading cell kinetic delay, independent of functional p53.
Topics: Antineoplastic Agents, Phytogenic; Caffeine; Cell Cycle; Cell Division; Cell Line, Transformed; Central Nervous System Stimulants; Demecolcine; DNA; Dose-Response Relationship, Drug; Fibroblasts; G2 Phase; Gamma Rays; Genes, Dominant; Humans; Kinetics; Mitosis; Mutation; Phenotype; Purines; Pyrimidines; Time Factors; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2001 |
Screening method for inherited disorders of purine and pyrimidine metabolism by capillary electrophoresis with reversed electroosmotic flow.
Topics: Adolescent; Child; Child, Preschool; Electrophoresis, Capillary; Female; Humans; Infant; Male; Metabolism, Inborn Errors; Purines; Pyrimidines; Reproducibility of Results; Sensitivity and Specificity | 2002 |
Structural heterogeneity of pyrimidine/purine-biased DNA sequence analyzed by atomic force microscopy.
Topics: DNA; Microscopy, Atomic Force; Nucleic Acid Conformation; Plasmids; Purines; Pyrimidines | 2002 |
Normal transcription of the C1 inhibitor gene is dependent upon a polypurine-polypyrimidine region within the promoter.
Topics: Blotting, Southwestern; Complement C1 Inactivator Proteins; Complement C1 Inhibitor Protein; DNA-Binding Proteins; Electrophoresis; Gene Expression; Hepatocyte Nuclear Factor 1; Hepatocyte Nuclear Factor 1-alpha; Hepatocyte Nuclear Factor 1-beta; Humans; Mutation; Nuclear Proteins; Promoter Regions, Genetic; Purines; Pyrimidines; Serpins; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured | 2002 |
Long-patch base excision repair of apurinic/apyrimidinic site DNA is decreased in mouse embryonic fibroblast cell lines treated with plumbagin: involvement of cyclin-dependent kinase inhibitor p21Waf-1/Cip-1.
Topics: Animals; Base Sequence; Cell Cycle; Cell Division; Cell Line; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA Polymerase beta; DNA Repair; Embryo, Mammalian; Fibroblasts; Mice; Molecular Sequence Data; Mutation; Naphthoquinones; Proliferating Cell Nuclear Antigen; Purines; Pyrimidines; Reactive Oxygen Species | 2002 |
[Purine regulon of gamma-proteobacteria: a detailed description].
Topics: Adenosine Monophosphate; Bacterial Proteins; Carbohydrate Dehydrogenases; Escherichia coli Proteins; Gammaproteobacteria; Gene Expression Regulation, Bacterial; Genomics; Guanosine Monophosphate; Inosine Monophosphate; Membrane Transport Proteins; Peptide Synthases; Phosphoglycerate Dehydrogenase; Purines; Pyrimidines; Regulon; Repressor Proteins; Serine; Tetrahydrofolates | 2002 |
Metabolic flux in both the purine mononucleotide and histidine biosynthetic pathways can influence synthesis of the hydroxymethyl pyrimidine moiety of thiamine in Salmonella enterica.
Topics: Aminoimidazole Carboxamide; Bacterial Proteins; Gene Expression Regulation, Bacterial; Histidine; Point Mutation; Purines; Pyrimidines; Ribonucleotides; Salmonella enterica; Suppression, Genetic; Thiamine; Thiamine Pyrophosphate | 2002 |
2-Aminopurine electronic structure and fluorescence properties in DNA.
Topics: 2-Aminopurine; Dimerization; DNA; Electrons; Fluorescence Resonance Energy Transfer; Guanine; Models, Chemical; Models, Molecular; Purines; Pyrimidines; Thymine | 2002 |
[Separation and determination of purine bases and pyrimidine bases from nucleic acid hydrolysis by HPLC on BDS column].
Topics: Adenine; Chromatography, High Pressure Liquid; Cytosine; Guanine; Hypoxanthine; Nucleic Acids; Purines; Pyrimidines; Thymine; Uracil; Yeasts | 2000 |
Formation of stable triplexes between purine RNA and pyrimidine oligodeoxyxylonucleotides.
Topics: Animals; Base Sequence; Circular Dichroism; DNA; Hydrogen-Ion Concentration; Mice; Nucleic Acid Conformation; Nucleic Acid Denaturation; Oligodeoxyribonucleotides; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-pim-1; Purines; Pyrimidines; RNA; RNA, Messenger; Temperature; Transcription, Genetic; Xylose | 2003 |
A spectrophotometric method for the analysis of the purine and pyrimidine components of ribonucleic acid.
Topics: Nucleic Acids; Purines; Pyrimidines; RNA; Spectrophotometry | 1952 |
The purine and pyrimidine composition of yeast ribonucleic acid.
Topics: Nucleic Acids; Purines; Pyrimidines; RNA; Yeasts | 1952 |
[Purine and pyrimidine metabolism].
Topics: Nucleic Acids; Purines; Pyrimidines | 1952 |
The nucleic acids of some insect viruses.
Topics: Adenine; Cytosine; DNA; Guanine; Insect Viruses; Nucleic Acids; Purines; Pyrimidines; Thymine; Viruses | 1952 |
[Action of a biochemical environment on the reproduction of influenza virus in tissue culture. IV. Action of pyrimidine and purine bases, nucleoside and nucleotides].
Topics: Nucleosides; Nucleotides; Orthomyxoviridae; Purines; Pyrimidines | 1952 |
The purine and pyrimidine metabolism of normal and phage-infected Escherichia coli.
Topics: Bacteriophages; Escherichia coli; Humans; Metabolic Networks and Pathways; Purines; Pyrimidines | 1953 |
Purine and pyrimidine metabolism in microorganisms.
Topics: Bacteria; Purines; Pyrimidines; Yeasts | 1953 |
[The characterization of some purine and pyrimidine derivatives by determination of the melting-point of their eutectics with dicyandiamide].
Topics: Amidines; Cardiovascular Agents; Guanidines; Purines; Pyrimidines | 1952 |
The purine and pyrimidine composition of some deoxyribonucleic acids from tumours.
Topics: DNA; Neoplasms; Nucleic Acids; Purines; Pyrimidines | 1954 |
Utilization of purine and pyrimidine compounds in nucleic acid synthesis by Escherichia coli.
Topics: Escherichia coli; Metabolic Networks and Pathways; Nucleic Acids; Purines; Pyrimidines | 1954 |
The isolation of plant nucleic acid fractions for purine and pyrimidine determinations.
Topics: Nucleic Acids; Plants; Purines; Pyrimidines | 1954 |
Metabolism of purine and pyrimidine compounds by vibrios.
Topics: Metabolic Networks and Pathways; Purines; Pyrimidines; Vibrio | 1954 |
Conservation of nucleic acids during bacterial growth.
Topics: Bacteria; Escherichia coli; Nucleic Acids; Purines; Pyrimidines | 1954 |
The purine and pyrimidine composition of the tobacco mosaic virus and the Holmes masked strain.
Topics: Phosphorus; Purines; Pyrimidines; Tobacco Mosaic Virus; Viruses | 1954 |
Nucleic acids. VII. A combination of several methods for determination of purine and pyrimidine bases in DNA with minor modifications.
Topics: DNA; Nucleic Acids; Purines; Pyrimidines | 1955 |
The effect of purine and pyrimidine analogues on enzyme induction in Mycobacterium tuberculosis.
Topics: Enzyme Induction; Mycobacterium tuberculosis; Purines; Pyrimidines | 1955 |
[Purine and pyrimidine bases of desoxyribonucleic acids in Ehrlich ascites carcinoma in mouse].
Topics: Animals; Ascites; DNA; Kidney; Liver; Mice; Neoplasms; Nucleic Acids; Purines; Pyrimidines | 1955 |
The isolation of nucleic acid fractions from plant leaves and their purine and pyrimidine composition.
Topics: Nucleic Acids; Plant Leaves; Plants; Purines; Pyrimidines | 1956 |
A separation in weak magnesium chloride solutions of nuclear material into two fractions with different purine and pyrimidine content; with a note on two unknown substances with a high absorption in the ultra-violet.
Topics: Cell Nucleus; Humans; Magnesium Chloride; Metabolic Networks and Pathways; Purines; Pyrimidines; Viola | 1956 |
Coronary vasodilator properties of purine and pyrimidine derivatives.
Topics: Coronary Vessels; Heart; Humans; Purines; Pyrimidines; Vasodilator Agents | 1956 |
[Comparison of contents of purine and pyrimidine bases and of desoxyribonucleic acids in certain animal species].
Topics: Animals; Biochemical Phenomena; DNA; Purines; Pyrimidines | 1956 |
The effect of antimetabolites on the growth of Endamoeba histolytica. I. Purine and pyrimidine analogs.
Topics: Antimetabolites; Entamoeba histolytica; Purines; Pyrimidines | 1957 |
Proteinase biosynthesis by Streptococcus liquefaciens. II. Purine, pyrimidine, and vitamin requirements.
Topics: Hydrolases; Peptide Hydrolases; Purines; Pyrimidines; Streptococcus; Vitamins | 1957 |
Purine and pyrimidine transaminases in Escherichia coli.
Topics: Escherichia coli; Purines; Pyrimidines; Transaminases | 1957 |
[Possibility of chemotherapy for neoplasms with pyrimidine & purine antagonists].
Topics: Antimetabolites; Humans; Neoplasms; Purines; Pyrimidines | 1957 |
Purine and pyrimidine derivatives in the acid-soluble fraction of animal tissues and cell nuclei.
Topics: Animals; Cell Nucleus; Nucleosides; Nucleotides; Purines; Pyrimidines | 1958 |
Degradation of some purine and pyrimidine derivatives by hot alkali.
Topics: Alkalies; Nucleosides; Nucleotides; Purines; Pyrimidines | 1958 |
Effect of purine and pyrimidine ribosides on an isolated frog ventricle preparation.
Topics: Congenital Abnormalities; Humans; Nucleosides; Nucleotides; Purines; Pyrimidines | 1958 |
Special microbiological systems. III. The use of lactic acid bacteria for the evaluation of purine and pyrimidine antagonists.
Topics: Lactic Acid; Lactobacillus; Purines; Pyrimidines | 1958 |
[Coacervates containing purine and pyrimidine compounds].
Topics: Purines; Pyrimidines | 1959 |
The origin of purine and pyrimidine deoxyribose in Escherichia coli systems.
Topics: Deoxyribose; Escherichia coli; Nucleosides; Nucleotides; Purines; Pyrimidines; Ribose | 1959 |
[Effect of succinic peroxide on the purine & pyrimidine bases of desoxyribonucleic acid].
Topics: DNA; Nitrogen; Peroxides; Purines; Pyrimidines; Succinates | 1959 |
Inhibition of mold development by purine and pyrimidine analogs.
Topics: Aspergillus; Aspergillus niger; Fungi; Purines; Pyrimidines | 1959 |
[Mutagenic action of some purine and pyrimidine compounds].
Topics: Genetics; Nucleosides; Nucleotides; Purines; Pyrimidines | 1960 |
Separation and estimation of purine and pyrimidine bases from a heated suspension of Micrococcus flavus.
Topics: Alkalies; Micrococcus; Purines; Pyrimidines; Suspensions | 1960 |
Amino acid starvation in an Escherichia coli auxotroph. II. Acidsoluble purine and pyrimidine derivatives in normal and starved cells.
Topics: Amino Acids; Escherichia coli; Leuconostoc; Purines; Pyrimidines; Starvation | 1960 |
Purine and pyrimidine metabolism in Rhodospirillum rubrum.
Topics: Biochemical Phenomena; Metabolic Networks and Pathways; Purines; Pyrimidines; Rhodospirillum; Rhodospirillum rubrum | 1961 |
A colorimetric determination of purine and pyrimidine deoxyribonucleosides and their phosphorylated derivatives.
Topics: Deoxyribonucleosides; Humans; Purines; Pyrimidines; RNA | 1961 |
Effects of 4-aminopyrazolo (3,4-d)pyrimidine and 1-methyl-4-aminopyrazolo(3,4-d)pyrimidine on nucleic acid purine metabolism in ascites tumors.
Topics: Adenine; Ascites; Neoplasms; Nucleic Acids; Purines; Pyrimidines | 1961 |
Malic enzyme induction by lactic acid bacteria. II. Purine and pyrimidine requirements.
Topics: Enzyme Induction; Lactic Acid; Lactobacillus; Lyases; Malate Dehydrogenase; Purines; Pyrimidines | 1961 |
Extraction, hydrolysis, and electrophoretic analysis of ribonucleic acid from microscopic tissue units (microphoresis).
Topics: Hydrolysis; Purines; Pyrimidines; RNA | 1960 |
Radiosensitization of E. coli by purine and pyrimidine analogues incorporated in deoxyribonucleic acid.
Topics: Antimetabolites; DNA; Escherichia coli; Purines; Pyrimidines | 1961 |
[The chromatoclasic effect of ethylene oxide: action on the purine and pyrimidine bases of nucleic acids].
Topics: Chromosomes; Ethylene Oxide; Nucleic Acids; Purines; Pyrimidines | 1960 |
Purine and pyrimidine excretion in normal and leukemic subjects.
Topics: Humans; Leukemia; Purines; Pyrimidines | 1960 |
[Effects of dietetic administration of DL-ethionine: hepatic content of purine and pyrimidine bases].
Topics: Diet; Dietetics; Ethionine; Humans; Liver; Nutrition Assessment; Nutritional Status; Purines; Pyrimidines | 1959 |
Effect of purine and pyrimidine analogues on reversion of a tryptophan-requiring strain of Escherichia coli.
Topics: Antimetabolites; Escherichia coli; Purines; Pyrimidines; Tryptophan | 1959 |
The inhibition of hemagglutinin formation in mice by purine and pyrimidine analogues.
Topics: Animals; Antibodies; Antimetabolites; Hemagglutinins; Mice; Purines; Pyrimidines | 1962 |
Antagonists of purine and pyrimidine metabolites and of folic acid.
Topics: Antimetabolites; Antineoplastic Agents; Folic Acid; Folic Acid Antagonists; Humans; Purines; Pyrimidines | 1961 |
Preparative-scale chromatographic separation of purine and pyrimidine bases and their deoxyribonucleosides.
Topics: Chromatography; Deoxyribonucleosides; Nucleic Acids; Purines; Pyrimidines | 1962 |
[Tautomerism of purine and pyrimidine bases and the theory of mutations].
Topics: Mutation; Purines; Pyrimidines | 1962 |
[On the problem of the specific interrelation of purine and pyrimidine in the nucleic acid chain].
Topics: Nucleic Acids; Purines; Pyrimidines; Spectrum Analysis | 1963 |
Ultraviolet microscopy of purine compounds in the yeast vacuole.
Topics: Candida; Microscopy, Ultraviolet; Nucleic Acids; Purines; Pyrimidines; Saccharomyces cerevisiae; Vacuoles; Yeasts | 1963 |
Effect of amino acid, purine, and pyrimidine analogues on activation of corneal stromal cells to take up neutral red.
Topics: Amino Acids; Antimetabolites; Cornea; Neutral Red; Purines; Pyrimidines; Stromal Cells | 1962 |
Acid-soluble purine and pyrimidine compounds of mammalian spermatozoa.
Topics: Adenine Nucleotides; Cytosine Nucleotides; Guanine Nucleotides; Male; Purines; Pyrimidines; Spermatozoa | 1962 |
Autoradiographic studies of the differential incorporation of glycine, and purine and pyrimidine ribosides by Paramecium aurelia.
Topics: Glycine; Humans; Nucleosides; Paramecium; Paramecium aurelia; Purines; Pyrimidines; Thymidine | 1963 |
[Comparative action of purine and pyrimidine derivatives on the isolated heart during hypodynamia].
Topics: Antihypertensive Agents; Heart; Humans; Hypokinesia; Purines; Pyrimidines | 1963 |
INTERACTION OF PURINES WITH THE PYRIMIDINE TRANSPORT PROCESS OF THE SMALL INTESTINE.
Topics: Adenine; Caffeine; Carbon Isotopes; Guanine; Intestine, Small; Intestines; Mercaptopurine; Pharmacology; Physiology; Purines; Pyrimidines; Rats; Research; Theobromine; Theophylline; Uracil; Uric Acid; Xanthines | 1963 |
PURINE AND PYRIMIDINE DERIVATIVES IN MATURE PEA SEEDS.
Topics: Chromatography; Coenzyme A; Ion Exchange Resins; Metabolism; Nucleosides; Pisum sativum; Purines; Pyrimidines; Research; Seeds; Ultraviolet Rays | 1963 |
PARTICIPATION OF PURINE AND PYRIMIDINE NUCLEOTIDE SEQUENCES IN THE MOLECULE OF CALF THYMUS DEOXYRIBONUCLEIC ACID.
Topics: Animals; Cattle; Chemical Phenomena; Chemistry; DNA; Nucleotides; Purines; Pyrimidine Nucleotides; Pyrimidines; Research; Thymus Gland | 1963 |
[DIPOLAR MOMENTS AND MOMENTS OF TRANSITION OF PURINE AND PYRIMIDINE BASES OF BIOLOGICAL INTEREST].
Topics: Chemical Phenomena; Chemistry; Purines; Pyrimidines; Research | 1963 |
THE DISTRIBUTION OF NUCLEOTIDES INTO PYRIMIDINE AND PURINE NUCLEOTIDE CLUSTERS IN THE POLYNUCLEOTIDE CHAIN OF DNA FROM ESCHERICHIA COLI C.
Topics: DNA; DNA, Bacterial; Escherichia coli; Metabolism; Nucleotides; Phosphorus Isotopes; Polynucleotides; Purine Nucleotides; Purines; Pyrimidines; Research; Ribonucleases | 1963 |
THE MECHANISM OF ACTION OF PURINE AND PYRIMIDINE ANALOGS IN MICROORGANISMS.
Topics: Amino Acids; Antimetabolites; Azaguanine; Candida; Carbon Isotopes; Fluorouracil; Nucleoproteins; Phenylalanine; Proline; Proteins; Purines; Pyrimidines; Research; RNA | 1963 |
[SEMI-CONDUCTIBILITY OF DNA (DESOXYRIBONUCLEIC ACID) AND OF PURINE AND PYRIMIDINE BASES OF DNA AND RNA (RIBONUCLEIC ACID)].
Topics: Adenine; Cytosine; DNA; Electrophysiology; Guanine; Purines; Pyrimidines; Research; RNA; Thymine; Uracil | 1963 |
STUDIES ON THE ACTIONS OF PYRAZOLOPYRIMIDINES IN MICROORGANISMS. I. 4-HYDROXY-6-AMINOPYRAZOLOPYRIMIDINE.
Topics: Adenine; Antimetabolites; Bacillus cereus; Carbon Isotopes; Culture Media; Escherichia coli; Formates; Guanine; Methionine; Mutation; Pharmacology; Phosphates; Phosphorus Isotopes; Purines; Pyrazoles; Pyrimidines; Research; RNA; RNA, Bacterial | 1964 |
STUDIES ON THE ACTIONS OF PYRAZOLOPYRIMIDINES IN MICROORGANISMS. II. 4-AMINOPYRAZOLOPYRIMIDINE.
Topics: Acetates; Adenine; Antimetabolites; Bacillus cereus; Carbon Isotopes; Escherichia coli; Formates; Glycine; Guanine; Histidine; Leucine; Methionine; Nucleosides; Pharmacology; Phosphates; Phosphorus Isotopes; Pimelic Acids; Proteins; Purines; Pyrazoles; Pyrimidines; Research; Uracil | 1964 |
[ON MOBILITY OF PURINES AND PYRIMIDINE BASES AND THEIR DERIVATIVES DURING ELECTROPHORETIC SEPARATION].
Topics: Adenine; Adenine Nucleotides; Cytosine Nucleotides; Electrophoresis; Guanine; Nucleosides; Nucleotides; Purines; Pyrimidines; Research; Thymidine; Thymine; Uracil | 1964 |
STUDIES ON THE ANALYSIS OF PURINE AND PYRIMIDINE BASES OF NUCLEIC ACID. III. A DIRECT SPECTROPHOTOMETRIC METHOD FOR THE ANALYSIS OF THE PURINE AND PYRIMIDINE BASES IN DNA.
Topics: Adenine; Cytosine; DNA; Guanine; Nucleic Acids; Purines; Pyrimidines; Spectrophotometry; Thymine | 1964 |
PURINE- AND PYRIMIDINE-SPECIFIC ANTIBODIES: EFFECT ON THE FERTILIZED SEA URCHIN EGG.
Topics: Animals; Antibodies; Antigens; Echinodermata; Immune Sera; Ovum; Purines; Pyrimidines; Rabbits; Research; Sea Urchins; Zygote | 1964 |
REGULATION AND COORDINATION OF PURINE AND PYRIMIDINE BIOSYNTHESES IN YEAST. I. REGULATION OF PURINE BIOSYNTHESIS AND ITS RELATION TO TRANSIENT CHANGES IN INTRACELLULAR NUCLEOTIDE LEVELS.
Topics: Adenine; Carbon Isotopes; Metabolism; Nucleotides; Purines; Pyrimidines; Research; Ribonucleotides; Saccharomyces; Saccharomyces cerevisiae | 1964 |
FORMATION OF RIBOMONONUCLEOTIDES FROM PURINE AND PYRIMIDINE BASES AND 5'-PHOSPHORIBOSYLPYROPHOSPHATE BY A SALMON MILT EXTRACT.
Topics: Adenine; Adenine Nucleotides; Animals; Carbon Isotopes; Chromatography; Cytosine; Cytosine Nucleotides; Diphosphates; Fishes; Guanine; Guanine Nucleotides; Metabolism; Nucleotides; Orotic Acid; Phosphoribosyl Pyrophosphate; Purines; Pyrimidines; Research; Salmon; Thymine; Tissue Extracts; Tritium; Uracil; Uracil Nucleotides; Xanthines | 1964 |
[ON THE ACTION OF CERTAIN PURINE AND PYRIMIDINE BASES ON THE INDUCTION OF LYSIS INDUCED BY IRRADIATION OF CULTURES OF LYSOGENIC ESCHERICHIA COLI BY ULTRAVIOLET RAYS AND ON SOME ELECTRONIC ASPECTS OF THIS ACTION].
Topics: Adenine; Bacteriolysis; Cytosine; Escherichia coli; Pharmacology; Purines; Pyrimidines; Radiation Effects; Research; Thymine; Ultraviolet Rays | 1964 |
THE INTERACTIONS OF PURINE AND PYRIMIDINE BASES WITH 4-DIMETHYLAMINOAZOBENZENE AND 4-AMINOAZOBENZENE.
Topics: Azo Compounds; Biochemical Phenomena; Biochemistry; p-Aminoazobenzene; p-Dimethylaminoazobenzene; Purines; Pyrimidines; Research; Spectrophotometry | 1964 |
REVERSIBLE SONIC INHIBITION OF PROTEIN, PURINE, AND PYRIMIDINE BIOSYNTHESIS IN THE LIVING CELL.
Topics: Metabolism; Proteins; Purines; Pyrimidines; Research; Saccharomyces; Sound | 1964 |
PURINE- AND PYRIMIDINE-SPECIFIC ANTIBODIES: PRECIPITATION WITH DENATURED DEOXYRIBONUCLEIC ACID.
Topics: Antibodies; Chemical Precipitation; DNA; Purines; Pyrimidines; Research | 1964 |
GROWTH INHIBITION OF CLOSTRIDIUM FESERI BY CARCINOSTATIC PURINE AND PYRIMIDINE ANALOGS. I. EFFECT OF MEDIUM ON GROWTH INHIBITION.
Topics: Adenocarcinoma; Antineoplastic Agents; Clostridium; Culture Media; Neoplasms; Neoplasms, Experimental; Pharmacology; Purines; Pyrimidines; Research; Tissue Culture Techniques | 1964 |
THE ROLE OF PURINE AND PYRIMIDINE BASES AND THEIR ANALOGUES IN RADIATION SENSITIVITY.
Topics: Bacillus subtilis; Coliphages; DNA; DNA, Bacterial; Escherichia coli; Glycerol; Oxygen; Pharmacology; Purines; Pyrimidines; Radiation Effects; Radiation Tolerance; Radiation-Protective Agents; Research; Ultraviolet Rays | 1964 |
INHIBITION OF THE BIOSYNTHESIS OF THE PYRIMIDINE PORTION OF THIAMINE BY ADENOSINE.
Topics: Adenosine; Enterobacter aerogenes; Histidine; Metabolism; Mutation; Nucleosides; Pharmacology; Purines; Pyrimidines; Research; Succinates; Thiamine; Thiazoles | 1964 |
METABOLIC STUDIES ON THE SUGARS OF NUCLEIC ACIDS. I. THE ISOLATION OF PYRIMIDINE-BOUND SUGARS AND UTILIZATION OF (14C6)GLUCOSE FOR RIBOSE FORMATION IN MAMMALIAN TISSUES IN VITRO.
Topics: Animals; Carbohydrate Metabolism; Carcinoma, Ehrlich Tumor; Glucose; In Vitro Techniques; Liver; Mice; Neoplasms; Nucleic Acids; Nucleosides; Nucleotides; Purines; Pyrimidines; Rats; Research; Ribose; RNA; RNA, Neoplasm; Spleen; Thymus Gland | 1964 |
[INFLUENCE OF THE HYDROGEN BOND ON THE DIPOLAR MOMENT OF PURINE-PYRIMIDINE PAIRS OF NUCLEIC ACIDS].
Topics: Acetates; Adenine; Amines; Biochemical Phenomena; Biochemistry; Cytosine; Guanine; Hydrogen; Nucleic Acids; Purines; Pyridines; Pyrimidines; Research; Thymine | 1964 |
[ON THE SEMI-CONDUCTIVITY OF PURINE AND PYRIMIDINE BASES OF NUCLEIC ACIDS].
Topics: Adenine; Chemical Phenomena; Chemistry, Physical; Cytosine; Guanine; Nucleic Acids; Purines; Pyrimidines; Research; Thymine; Uracil | 1964 |
4-HYDROXYPYRAZOLO (3,4-D) PYRIMIDINE (HPP) IN THE TREATMENT OF GOUT: PRELIMINARY OBSERVATIONS.
Topics: Blood; Colchicine; Diet; Diet Therapy; Drug Therapy; Enzyme Inhibitors; Geriatrics; Gout; Humans; Probenecid; Purines; Pyrazoles; Pyrimidines; Toxicology; Uric Acid; Urine; Xanthine Oxidase; Xanthines | 1964 |
METABOLISM OF LEPTOSPIRAE. I. UTILIZATION OF AMINO ACIDS AND PURINE, AND PYRIMIDINE BASES.
Topics: Amidohydrolases; Amino Acids; Ammonia; Autoradiography; Leptospira; Metabolism; Purines; Pyrimidines; Rabbits; Research | 1964 |
3-RIBOSYLPURINES. I. SYNTHESIS OF (3-RIBOSYLURIC ACID) 5'-PHOSPHATE AND (3-RIBOSYLXANTHINE) 5'-PHOSPHATE BY A PYRIMIDINE RIBONUCLEOTIDE PYROPHOSPHORYLASE OF BEEF ERYTHROCYTES.
Topics: Animals; Carbon Isotopes; Cattle; Chemical Phenomena; Chemistry; Chromatography; Erythrocytes; Glucosyltransferases; Metabolism; Nucleotides; Orotic Acid; Phosphates; Pterins; Purines; Pyrimidines; Research; Ribonucleosides; Ribonucleotides; Ribose; Spectrophotometry; Uracil; Uric Acid; Xanthines | 1964 |
INTERMOLECULAR FORCES IN ASSOCIATION OF PURINES WITH POLYBENZENOID HYDROCARBONS.
Topics: Adenine; Benzopyrenes; Caffeine; Chemical Phenomena; Chemistry; Cytosine; Guanine; Hypoxanthines; London; Purines; Pyrimidines; Research; Thymine; Uracil; Uric Acid; Xanthines | 1965 |
INFLUENCE OF PURINE AND PYRIMIDINE COMPOUNDS ON DNA-SYNTHESIS OF ASCITES-TUMOUR CELLS.
Topics: Animals; Ascites; Carcinoma, Ehrlich Tumor; Cytosine Nucleotides; DNA; DNA, Neoplasm; Fluorouracil; Metabolism; Neoplasms, Experimental; Nucleotides; Pharmacology; Phosphorus Isotopes; Purines; Pyrimidines; Research; Thymine; Uracil; Uracil Nucleotides | 1964 |
IMMUNOADSORBENT FOR THE ISOLATION OF PURINE-SPECIFIC ANTIBODIES.
Topics: Animals; Antibodies; Cattle; Cellulose; Immune Sera; Immunoelectrophoresis; Immunosorbents; Indicators and Reagents; Precipitin Tests; Purines; Pyrimidines; Research; Serum Albumin; Serum Albumin, Bovine; Spectrophotometry | 1965 |
METHYLATED PURINES AND PYRIMIDINES. I. SYNTHESES OF 8-HYDROXY-7-METHYLGUANINE AND METHYLATION OF A 5-(BENZYLIDENEAMINO) PYRIMIDINE.
Topics: Acetates; Alkylation; Chemical Phenomena; Chemistry; Guanine; Malonates; Methylation; Purines; Pyrimidines; Research | 1965 |
The purine and pyrimidine requirements of Glaucoma scintillans.
Topics: Biochemical Phenomena; Ciliophora; Glaucoma; Humans; Purines; Pyrimidines | 1955 |
Studies in the enzyme make-up of Pasteurella pestis. Part VII. Deamination of purine and pyrimidine compounds by virulent and avirulent strains.
Topics: Deamination; Purines; Pyrimidines; Yersinia pestis | 1960 |
The electronic structure of the purine-pyrimidine pairs of DNA.
Topics: DNA; Purines; Pyrimidines | 1959 |
[Inhibition of the multiplication in vitro of poliomyelitis viruses by guanidine. VII. Absence of interference of vitamins, purine and pyrimidine bases in the inhibition by guanidine].
Topics: Amidines; Guanidine; Guanidines; In Vitro Techniques; Poliomyelitis; Poliovirus; Purines; Pyrimidines; Vitamins | 1962 |
Interaction of steroids with some pyrimidine and purine derivatives.
Topics: Purines; Pyrimidines; Steroids | 1962 |
The interaction of ribonuclease with purine and pyrimidine phosphates. I. Binding of adenosine 5'-monophosphate to ribonuclease.
Topics: Adenine Nucleotides; Adenosine; Adenosine Monophosphate; Phosphates; Purines; Pyrimidines; Ribonucleases | 1962 |
Role of one-carbon precursors in the biosynthesis of deoxyribonucleic acid in bacteriophage infected and growing cells of Escherichia coli.
Topics: Bacteriological Techniques; Bacteriophages; Carbon; Carbon Isotopes; DNA; Escherichia coli; Formates; Glycine; Purines; Pyrimidines; Serine | 1961 |
Mutagenesis of human DNA polymerase lambda: essential roles of Tyr505 and Phe506 for both DNA polymerase and terminal transferase activities.
Topics: Amino Acid Sequence; Amino Acid Substitution; Binding Sites; Catalysis; DNA Polymerase beta; DNA Replication; Humans; Kinetics; Multienzyme Complexes; Mutagenesis; Mutation; Purines; Pyrimidines; Structure-Activity Relationship | 2003 |
Purine and pyrimidine-specific repression of the Escherichia coli carAB operon are functionally and structurally coupled.
Topics: Bacterial Proteins; Base Sequence; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); DNA; DNA-Binding Proteins; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Models, Molecular; Molecular Sequence Data; Mutation; Operon; Promoter Regions, Genetic; Protein Binding; Purines; Pyrimidines; Repressor Proteins; Transcription, Genetic | 2004 |
The purine and pyrimidine content of three strains of Escherichia coli.
Topics: Escherichia coli; Purines; Pyrimidines | 1951 |
[Effect of some purine and pyrimidine compounds on alloxan diabetes].
Topics: Animals; Diabetes Mellitus; Diabetes Mellitus, Experimental; Purines; Pyrimidines | 1950 |
Purine and pyrimidine content of the nucleic acids of nuclei and cytoplasm.
Topics: Cells; Cytoplasm; Humans; Nucleic Acids; Purines; Pyrimidines | 1951 |
The effect of carcinogenic azo-dye on the purine & pyrimidine content of liver desoxyribonucleic acid.
Topics: Azo Compounds; Carcinogens; DNA; Liver; Purines; Pyrimidines | 1951 |
The purine and pyrimidine composition of deoxypentose nucleic acids.
Topics: Nucleic Acids; Purines; Pyrimidines | 1951 |
[Effect of ultrasonics on purine and pyrimidine bases].
Topics: Purines; Pyrimidines; Ultrasonics | 1952 |
Studies on purine and pyrimidine requirements of a strain of Streptococcus faecalis.
Topics: Enterococcus faecalis; Purines; Pyrimidines; Streptococcus | 1951 |
The enzymically catalysed transfer of the deoxyribosyl group from one purine or pyrimidine to another.
Topics: Catalysis; DNA; Endonucleases; Purines; Pyrimidines; RNA | 1952 |
Effects of purine and pyrimidine analogues on development of Rana pipiens.
Topics: Animals; Antimetabolites; Nucleic Acids; Purines; Pyrimidines; Rana pipiens | 1952 |
[Activity of various purine and pyrimidine derivatives on the growth of the Walker 256 carcinoma in rats].
Topics: Animals; Carcinoma 256, Walker; Neoplasms, Experimental; Purines; Pyrimidines; Rats | 1951 |
Purine-requiring and pyrimidine-requiring mutants of Saccharomyces cerevisiae.
Topics: Metabolic Networks and Pathways; Purines; Pyrimidines; Saccharomyces cerevisiae; Yeast, Dried | 1952 |
Purine and pyrimidine requirements of Lactobacillus leichmannii in the presence of vitamin B12 or thymidine.
Topics: Corrinoids; Humans; Lactobacillus; Lactobacillus leichmannii; Metabolic Networks and Pathways; Purines; Pyrimidines; Thymidine; Vitamin B 12 | 1952 |
Direct multicomponent analysis of beer samples constituents using micellar electrokinetic capillary chromatography.
Topics: Alcohols; Beer; Buffers; Chromatography, Micellar Electrokinetic Capillary; Filtration; Purines; Pyrimidines; Vitamins | 2004 |
Chromatographic studies of nucleic acids; a technique for the identification and estimation of purine and pyrimidine bases, nucleosides and related substances.
Topics: Chromatography; Humans; Nucleic Acids; Nucleosides; Purines; Pyrimidines | 1949 |
The effects of injection of purine and pyrimidine compounds on grafted mice.
Topics: Animals; Mice; Purines; Pyrimidines | 1949 |
The purine and pyrimidine requirements of Leuconostoc citrovorum 8081.
Topics: Bacteria; Leuconostoc; Purines; Pyrimidines | 1949 |
Purine and pyrimidine contents of some desoxypentose nucleic acids.
Topics: Adenine; Animals; Cattle; Cytosine; Guanine; Horses; Nucleic Acids; Purines; Pyrimidines; Sheep; Thymine | 1950 |
Further studies on the purine and pyrimidine metabolism of Tetrahymena.
Topics: Biochemical Phenomena; Biochemistry; Humans; Purines; Pyrimidines; Tetrahymena | 1950 |
Shift in purine/pyrimidine base recognition upon exchanging extracellular domains in P2Y 1/6 chimeric receptors.
Topics: Amino Acid Sequence; Animals; COS Cells; Humans; Molecular Sequence Data; Protein Structure, Tertiary; Purines; Pyrimidines; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Recombinant Fusion Proteins; Transfection | 2004 |
Human deoxycytidine kinase as a deoxyribonucleoside phosphorylase.
Topics: Catalysis; Deoxycytidine Kinase; Deoxyribonucleotides; Dithiothreitol; Humans; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Molecular Structure; Nucleotidases; Nucleotides; Phosphates; Purines; Pyrimidines; Substrate Specificity | 2004 |
The novel pyrimidine and purine derivatives of l-ascorbic acid: synthesis, one- and two-dimensional 1H and 13C NMR study, cytostatic and antiviral evaluation.
Topics: Antineoplastic Agents; Antiviral Agents; Ascorbic Acid; Carbon Isotopes; Cell Line, Tumor; Drug Evaluation, Preclinical; Humans; Magnetic Resonance Spectroscopy; Protons; Purines; Pyrimidines; Spectrophotometry, Ultraviolet | 2005 |
Etched chemically modified capillaries: novel separation media for electrophoretic analyses.
Topics: Buffers; Electrophoresis, Capillary; Hydrogen-Ion Concentration; Molecular Structure; Nucleosides; Peptides; Polyethylene Glycols; Proteins; Purines; Pyrimidines; Silicon | 2004 |
8-OxoA inhibits the incision of an AP site by the DNA glycosylases Fpg, Nth and the AP endonuclease HAP1.
Topics: Adenine; Base Sequence; Deoxyribonuclease (Pyrimidine Dimer); DNA; DNA Damage; DNA-(Apurinic or Apyrimidinic Site) Lyase; DNA-Formamidopyrimidine Glycosylase; Escherichia coli Proteins; Molecular Sequence Data; Purines; Pyrimidines; Radiation Dosage; Structure-Activity Relationship | 2005 |
Neutrophil chemotaxis: autotaxin induced attenuation of purine/pyrimidine signaling precede the overexpression of Integrin(s).
Topics: Cell Membrane; Chemotaxis, Leukocyte; Glucose-6-Phosphate Isomerase; Glycoproteins; Integrins; Models, Biological; Multienzyme Complexes; Neutrophils; Phosphodiesterase I; Phosphoric Diester Hydrolases; Purines; Pyrimidines; Pyrophosphatases | 2005 |
Molecular recognition via triplex formation of mixed purine/pyrimidine DNA sequences using oligoTRIPs.
Topics: Base Sequence; DNA; Hydrogen Bonding; Molecular Structure; Nucleic Acid Conformation; Oligonucleotides; Purines; Pyrimidines | 2005 |
Mitochondrial-encoded membrane protein transcripts are pyrimidine-rich while soluble protein transcripts and ribosomal RNA are purine-rich.
Topics: Adenosine Triphosphate; Codon; Computational Biology; Databases, Genetic; DNA, Mitochondrial; Evolution, Molecular; Humans; Membrane Proteins; Mitochondria; Open Reading Frames; Oxygen; Phosphorylation; Purines; Pyrimidines; RNA, Messenger; RNA, Ribosomal; RNA, Transfer | 2005 |
Structural investigation of bilayers formed by 1-palmitoyl-2-oleoylphosphatidylnucleosides.
Topics: Adenosine; Glycerophospholipids; Lipid Bilayers; Neutron Diffraction; Phase Transition; Phosphatidic Acids; Purines; Pyrimidines; Spectroscopy, Fourier Transform Infrared; Uridine; Water | 2006 |
Unique properties of purine/pyrimidine asymmetric PNA.DNA duplexes: differential stabilization of PNA.DNA duplexes by purines in the PNA strand.
Topics: Base Composition; Circular Dichroism; Deoxyribose; DNA, Single-Stranded; Nucleic Acid Conformation; Peptide Nucleic Acids; Purines; Pyrimidines; Thermodynamics; Water | 2006 |
7-Functionalized 7-deazapurine ribonucleosides related to 2-aminoadenosine, guanosine, and xanthosine: glycosylation of pyrrolo[2,3-d]pyrimidines with 1-O-acetyl-2,3,5-tri-O-benzoyl-D-ribofuranose.
Topics: Adenosine; Amination; Anions; Aza Compounds; Catalysis; Chromatography, High Pressure Liquid; Glycosylation; Guanosine; Magnetic Resonance Spectroscopy; Molecular Structure; Monosaccharides; Palladium; Purines; Pyrimidines; Ribonucleosides; Xanthines | 2006 |
Insight into the CSA tensors of nucleobase carbons in RNA polynucleotides from solution measurements of residual CSA: towards new long-range orientational constraints.
Topics: Adenine; Anisotropy; Carbon Isotopes; Molecular Conformation; Molecular Structure; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Polynucleotides; Purines; Pyrimidines; RNA; Solutions | 2006 |
Genome update: purine strand bias in 280 bacterial genomes.
Topics: Base Sequence; Bias; Genome, Bacterial; Genomics; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Purines; Pyrimidines | 2006 |
DNA and LNA oligonucleotides containing N2'-functionalised derivatives of 2'-amino-2'-deoxyuridine.
Topics: Deoxyuridine; DNA; Molecular Structure; Oligonucleotides; Purines; Pyrimidines | 2006 |
Synthesis and antiviral evaluation of alkoxyalkyl esters of acyclic purine and pyrimidine nucleoside phosphonates against HIV-1 in vitro.
Topics: Cell Line, Transformed; Esters; HIV-1; Humans; Organophosphonates; Prodrugs; Purines; Pyrimidines | 2006 |
Thermodynamic and kinetic characterization of ligand binding to the purine riboswitch aptamer domain.
Topics: 2-Aminopurine; 5' Untranslated Regions; Adenine; Aptamers, Nucleotide; Guanine; Ligands; Models, Molecular; Mutation; Nucleic Acid Conformation; Purines; Pyrimidines; Regulatory Sequences, Ribonucleic Acid; RNA, Bacterial; Thermodynamics | 2006 |
Association of poly-purine/poly-pyrimidine sequences with meiotic recombination hot spots.
Topics: Algorithms; Animals; Base Pairing; Chromosome Breakage; Chromosome Mapping; GC Rich Sequence; Humans; Meiosis; Microsatellite Repeats; Pan troglodytes; Polymorphism, Genetic; Purines; Pyrimidines; Recombination, Genetic; Saccharomyces cerevisiae; Sequence Analysis, DNA | 2006 |
Enhanced separation of purine and pyrimidine bases using carboxylic multiwalled carbon nanotubes as additive in capillary zone electrophoresis.
Topics: Electrophoresis, Capillary; Nanotubes, Carbon; Purines; Pyrimidines | 2006 |
Implementing tandem mass spectrometry as a routine tool for characterizing the complete purine and pyrimidine metabolic profile in urine samples.
Topics: Adolescent; Adult; Calibration; Child, Preschool; Female; Humans; Infant, Newborn; Male; Purines; Pyrimidines; Reference Standards; Tandem Mass Spectrometry | 2006 |
Modified pyrimidines specifically bind the purine riboswitch.
Topics: Adenine; Base Pairing; Binding Sites; Crystallography, X-Ray; Guanine; Nucleic Acid Conformation; Purines; Pyrimidines; Regulatory Sequences, Ribonucleic Acid; Ribosomes | 2006 |
Regulation of Vibrio polysaccharide synthesis and virulence factor production by CdgC, a GGDEF-EAL domain protein, in Vibrio cholerae.
Topics: Amino Acid Sequence; Bacterial Proteins; Binding Sites; Chemotaxis; Cyclic GMP; Escherichia coli Proteins; Flagella; Gene Expression Regulation, Bacterial; Oligonucleotide Array Sequence Analysis; Phosphoric Diester Hydrolases; Phosphorus-Oxygen Lyases; Polysaccharides, Bacterial; Purines; Pyrimidines; Reverse Transcriptase Polymerase Chain Reaction; Transcription, Genetic; Vibrio cholerae; Virulence Factors | 2007 |
Surface-enhanced Raman spectroscopy (SERS) for sub-micromolar detection of DNA/RNA mononucleotides.
Topics: Biosensing Techniques; DNA; Purines; Pyrimidines; Reproducibility of Results; RNA; Sensitivity and Specificity; Spectrum Analysis, Raman | 2006 |
Polymorphisms in folate, pyrimidine, and purine metabolism are associated with efficacy and toxicity of methotrexate in psoriasis.
Topics: 5' Untranslated Regions; Adenosine Deaminase; Adult; Folic Acid; Haplotypes; Humans; Hydroxymethyl and Formyl Transferases; Membrane Transport Proteins; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Multienzyme Complexes; Nucleotide Deaminases; Polymorphism, Genetic; Psoriasis; Purines; Pyrimidines; Reduced Folate Carrier Protein; Thymidylate Synthase | 2007 |
N9-benzyl-substituted 1,3-dimethyl- and 1,3-dipropyl-pyrimido[2,1-f]purinediones: synthesis and structure-activity relationships at adenosine A1 and A2A receptors.
Topics: Animals; Benzene; Chemical Phenomena; Chemistry, Physical; CHO Cells; Cricetinae; Cricetulus; Crystallography, X-Ray; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Methylation; Models, Molecular; Molecular Structure; Propane; Purines; Pyrimidines; Rats; Receptor, Adenosine A1; Receptors, Adenosine A2; Structure-Activity Relationship | 2007 |
Synthesis and characterization of some pyrimidine, purine, amino acid and mixed ligand complexes.
Topics: Adenine; Amino Acids; Barbital; Electrons; Ligands; Magnetics; Metals; Purines; Pyrimidines; Spectrophotometry, Infrared; Thiouracil | 2008 |
Effects of organosulfurs, isothiocyanates and vitamin C towards hydrogen peroxide-induced oxidative DNA damage (strand breaks and oxidized purines/pyrimidines) in human hepatoma cells.
Topics: Ascorbic Acid; Carcinoma, Hepatocellular; Cell Line, Tumor; Comet Assay; Cytoprotection; DNA Damage; Humans; Hydrogen Peroxide; Isothiocyanates; Organic Chemicals; Oxidation-Reduction; Purines; Pyrimidines; Sulfur | 2007 |
Effect of spermine conjugation on the interaction of acridine with alternating purine-pyrimidine oligodeoxyribonucleotides studied by CD, fluorescence and absorption spectroscopies.
Topics: Acridines; Circular Dichroism; Nucleic Acid Denaturation; Oligodeoxyribonucleotides; Purines; Pyrimidines; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Spermine; Temperature | 2008 |
The Separation of Purine and Pyrimidine Bases and of Nucleotides by Ion Exchange.
Topics: Humans; Ion Exchange; Nucleotides; Purines; Pyrimidines | 1949 |
Extremely low frequency (ELF) magnetic fields enhance chemically induced formation of apurinic/apyrimidinic (AP) sites in A172 cells.
Topics: Cell Line, Tumor; Cell Survival; DNA; DNA Damage; Electromagnetic Fields; Humans; Hydrogen Peroxide; Methyl Methanesulfonate; Mutagens; Purines; Pyrimidines; Radiation Tolerance | 2008 |
Purine and pyrimidine antagonism in a pyrimidine-deficient mutant of Neurospora.
Topics: Neurospora; Purines; Pyrimidines | 1948 |
Fluorescence and electrochemical detection of pyrimidine/purine transversion by a ferrocenyl aminonaphthyridine derivative.
Topics: DNA; Electrochemistry; Ferrous Compounds; Fluorescence; Hydrogen Bonding; Indicators and Reagents; Ligands; Models, Molecular; Molecular Structure; Naphthyridines; Point Mutation; Purines; Pyrimidines; Spectrometry, Fluorescence | 2008 |
PP07: new approaches, new knowledge, new challenges in human purine and pyrimidine metabolism.
Topics: Humans; Purines; Pyrimidines | 2008 |
The use of 10-23 DNAzyme to selectively destroy the allele of mRNA with a unique purine-pyrimidine dinucleotide.
Topics: Alleles; Cell Line, Tumor; DNA, Catalytic; DNA, Single-Stranded; Genes, p53; Humans; Oligonucleotides; Purines; Pyrimidines; RNA, Messenger; Tumor Suppressor Protein p53 | 2008 |
Inner-shell chemical shift of DNA/RNA bases and inheritance from their parent purine and pyrimidine.
Topics: Computer Simulation; DNA; Models, Chemical; Models, Molecular; Purines; Pyrimidines; RNA | 2008 |
PP07. Proceedings of the 12th International Symposium on Purine and Pyrimidine Metabolism in Man, Chicago, Illinois, USA, June 2007.
Topics: Humans; Purines; Pyrimidines | 2008 |
Membrane compartments and purinergic signalling.
Topics: Humans; Purines; Pyrimidines; Receptors, Purinergic P2; Signal Transduction | 2009 |
Synthesis and biological activity of a novel series of 6-substituted thieno[2,3-d]pyrimidine antifolate inhibitors of purine biosynthesis with selectivity for high affinity folate receptors over the reduced folate carrier and proton-coupled folate transpo
Topics: Animals; Anion Transport Proteins; Antineoplastic Agents; Biological Transport; Carrier Proteins; Cell Proliferation; CHO Cells; Cricetinae; Cricetulus; Folate Receptors, GPI-Anchored; Folic Acid Antagonists; Gene Expression Regulation; Humans; Hydrogen Bonding; Membrane Transport Proteins; Nucleosides; Phosphoribosylaminoimidazolecarboxamide Formyltransferase; Protons; Purines; Pyrimidines; Receptors, Cell Surface; Reduced Folate Carrier Protein; Substrate Specificity; Transfection | 2009 |
Improvement of purine and pyrimidine antimetabolite-based anticancer treatment by selective suppression of mycoplasma-encoded catabolic enzymes.
Topics: Antimetabolites, Antineoplastic; Drug Therapy; Humans; Models, Biological; Molecular Sequence Data; Mycoplasma; Mycoplasma Infections; Neoplasms; Pharmaceutical Preparations; Purines; Pyrimidines | 2009 |
Alternative I-D exchange reaction on pyrimidine and purine nuclei mediated by tributyltin hydride using THF-d8 as a deuterium source.
Topics: Deuterium Exchange Measurement; Purines; Pyrimidines; Trialkyltin Compounds | 2009 |
Purine and pyrimidine antagonism in the pyrimidine deficient Neurospora mutant, No. 1298.
Topics: Neurospora; Purines; Pyrimidines | 1947 |
Experiments on the synthesis of purine nucleosides; the configuration at the glycosidic centre in natural and synthetic pyrimidine and purine nucleosides.
Topics: Nucleosides; Purine Nucleosides; Purines; Pyrimidines | 1946 |
Experiments on the synthesis of purine nucleosides; the configuration of some synthetic purine and pyrimidine glycosides.
Topics: Glucosides; Glycosides; Nucleosides; Purine Nucleosides; Purines; Pyrimidines | 1946 |
Pyrimidine-purine and pyrimidine heterodinucleosides synthesis containing a triazole linkage.
Topics: Catalysis; Copper; Cyclization; Nucleic Acid Conformation; Oligonucleotides; Purines; Pyrimidines; Triazoles | 2010 |
Purine and pyrimidine metabolism in the fist decade of the 21st century--highlights and perspectives.
Topics: Animals; Humans; Purines; Pyrimidines | 2010 |
Requirement of purine and pyrimidine synthesis for colonization of the mouse intestine by Escherichia coli.
Topics: Alcohol Oxidoreductases; Animals; Aspartate Carbamoyltransferase; Carbon-Nitrogen Ligases; Colony Count, Microbial; Escherichia coli; Escherichia coli Proteins; Gastrointestinal Tract; Gene Deletion; Gene Expression Profiling; Germ-Free Life; Mice; Oxo-Acid-Lyases; Purines; Pyrimidines; Virulence | 2010 |
Sequence signatures of nucleosome positioning in Caenorhabditis elegans.
Topics: Algorithms; Animals; Base Composition; Base Sequence; Caenorhabditis elegans; DNA, Helminth; Genome, Helminth; Markov Chains; Nucleosomes; Purines; Pyrimidines; Sequence Analysis, DNA | 2010 |
Investigation of riboflavin sensitized degradation of purine and pyrimidine derivatives of DNA and RNA under UVA and UVB.
Topics: Deoxyguanosine; DNA; DNA Damage; Guanosine; Humans; Photolysis; Photosensitizing Agents; Purines; Pyrimidines; Reactive Oxygen Species; Riboflavin; RNA; Rose Bengal; Ultraviolet Rays | 2010 |
Brassinolide-improved development of Brassica napus microspore-derived embryos is associated with increased activities of purine and pyrimidine salvage pathways.
Topics: Brassica napus; Brassinosteroids; Carbon Isotopes; Cholestanols; Isotope Labeling; Metabolic Networks and Pathways; Nucleotides; Plant Proteins; Pollen; Purines; Pyrimidines; Seeds; Steroids, Heterocyclic | 2011 |
SiC nanoparticles-modified glassy carbon electrodes for simultaneous determination of purine and pyrimidine DNA bases.
Topics: Biosensing Techniques; Carbon; DNA; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Nanoparticles; Purines; Pyrimidines | 2011 |
Gene set analysis of purine and pyrimidine antimetabolites cancer therapies.
Topics: Antimetabolites; Antineoplastic Agents; Area Under Curve; Cell Line, Tumor; Deoxycytidine; Gemcitabine; Genes, Neoplasm; Humans; Neoplasms; Phenotype; Purines; Pyrimidines; Reproducibility of Results; Thioguanine | 2011 |
How flexible are DNA constituents? The quantum-mechanical study.
Topics: DNA; Nucleic Acid Conformation; Purines; Pyrimidines; Quantum Theory | 2011 |
Simultaneous determination of purine and pyrimidine metabolites in HPRT-deficient cell lines.
Topics: Cell Line; Chromatography, Liquid; Humans; Hypoxanthine Phosphoribosyltransferase; Mass Spectrometry; Purines; Pyrimidines | 2011 |
Genetic and molecular characterization reveals a unique nucleobase cation symporter 1 in Arabidopsis.
Topics: Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Biological Transport; Genetic Loci; Molecular Sequence Data; Mutagenesis, Insertional; Nucleobase Transport Proteins; Purines; Pyrimidines; Sequence Alignment; Symporters | 2012 |
Probing sequence-specific DNA flexibility in a-tracts and pyrimidine-purine steps by nuclear magnetic resonance (13)C relaxation and molecular dynamics simulations.
Topics: Base Sequence; DNA; Molecular Dynamics Simulation; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acid Conformation; Nucleotides; Purines; Pyrimidines | 2012 |
Poly(alizarin red)/graphene modified glassy carbon electrode for simultaneous determination of purine and pyrimidine.
Topics: Anthraquinones; Carbon; Electrodes; Glass; Graphite; Polymers; Purines; Pyrimidines | 2012 |
Electrochemical determination of purine and pyrimidine DNA bases based on the recognition properties of azocalix[4]arene.
Topics: Biosensing Techniques; Carbon; DNA; Electrochemical Techniques; Electrodes; Microscopy, Electron, Scanning; Purines; Pyrimidines | 2013 |
Electrochemical evaluation of DNA methylation level based on the stoichiometric relationship between purine and pyrimidine bases.
Topics: Biosensing Techniques; DNA; DNA Methylation; Electrochemical Techniques; Humans; Nanotubes, Carbon; Oxidation-Reduction; Purines; Pyrimidines | 2013 |
The physicochemical essence of the purine·pyrimidine transition mismatches with Watson-Crick geometry in DNA: A·C* versa A*·C. A QM and QTAIM atomistic understanding.
Topics: Algorithms; Base Pair Mismatch; Base Pairing; Chemical Phenomena; DNA; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Isomerism; Models, Chemical; Molecular Structure; Purines; Pyrimidines; Quantum Theory; Thermodynamics | 2015 |
Transcriptomic analysis of differentially expressed genes in the Ras1(CA)-overexpressed and wildtype posterior silk glands.
Topics: Animals; Animals, Genetically Modified; Bombyx; Cell Cycle; Computational Biology; Gene Expression Profiling; Gene Expression Regulation; High-Throughput Nucleotide Sequencing; Insulin; MAP Kinase Signaling System; Mechanistic Target of Rapamycin Complex 1; Molecular Sequence Annotation; Multiprotein Complexes; Neoplasms; Phosphatidylinositol 3-Kinases; Purines; Pyrimidines; raf Kinases; ras Proteins; Reproducibility of Results; Sequence Analysis, RNA; Signal Transduction; TOR Serine-Threonine Kinases; Transcriptome | 2014 |
Genetic control of differential acetylation in diabetic rats.
Topics: Acetylation; Acetyltransferases; Amino Acids; Animals; Citric Acid Cycle; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Fatty Acids; Gene Expression Regulation; Gluconeogenesis; Glycolysis; Liver; Male; Pentose Phosphate Pathway; Polymorphism, Genetic; Protein Processing, Post-Translational; Proteomics; Purines; Pyrimidines; Rats; Sequence Analysis, RNA; Sirtuin 3; Species Specificity; Transcription, Genetic | 2014 |
Folded conformations due to arene interactions in dissymmetric and symmetric butylidene-linker models based on pyrazolo[3,4-d]pyrimidine, purine and 7-deazapurine.
Topics: Crystallography, X-Ray; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Molecular Conformation; Purines; Pyrazoles; Pyrimidines; Pyrroles | 2014 |
Solution-phase parallel synthesis of acyclic nucleoside libraries of purine, pyrimidine, and triazole acetamides.
Topics: Acetamides; Molecular Structure; Nucleosides; Purines; Pyrimidines; Small Molecule Libraries; Solutions; Triazoles | 2014 |
Proceedings of the 15th International Symposium on Purine and Pyrimidine Metabolism in Man, June 9-13, 2013, Madrid, Spain.
Topics: Animals; Humans; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Pyrimidines | 2014 |
Novel developments in metabolic disorders of purine and pyrimidine metabolism and therapeutic applications of their analogs.
Topics: Awards and Prizes; Humans; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Pyrimidines | 2014 |
Design, synthesis, and biological evaluation of unconventional aminopyrimidine, aminopurine, and amino-1,3,5-triazine methyloxynucleosides.
Topics: 3T3 Cells; Animals; Antiviral Agents; Cell Line, Tumor; Cell Proliferation; Drug Design; HeLa Cells; HIV-1; HIV-2; Humans; Mice; Models, Molecular; Moloney murine sarcoma virus; Purines; Pyrimidines; Structure-Activity Relationship; Triazines; Virus Replication | 2015 |
Metabolomics analysis of metabolic effects of nicotinamide phosphoribosyltransferase (NAMPT) inhibition on human cancer cells.
Topics: Amino Acids; Cell Line, Tumor; Citric Acid Cycle; Cluster Analysis; Creatine; Glycolysis; Humans; Lipid Metabolism; Mass Spectrometry; Metabolic Networks and Pathways; Metabolome; Metabolomics; Neoplasms; Nicotinamide Phosphoribosyltransferase; Pentose Phosphate Pathway; Purines; Pyrimidines | 2014 |
Oxidation half-reaction of aqueous nucleosides and nucleotides via photoelectron spectroscopy augmented by ab initio calculations.
Topics: DNA; Nucleotides; Oxidation-Reduction; Photoelectron Spectroscopy; Purines; Pyrimidines; Quantum Theory; Water | 2015 |
Short-term effect of caffeine on purine, pyrimidine and pyridine metabolism in rice (Oryza sativa) seedlings.
Topics: Caffeine; Oryza; Purines; Pyridines; Pyrimidines; Seedlings | 2015 |
Phenolic Amides Are Potent Inhibitors of De Novo Nucleotide Biosynthesis.
Topics: Amides; Amidophosphoribosyltransferase; Biosynthetic Pathways; Enzyme Inhibitors; Escherichia coli; Escherichia coli Proteins; Phenol; Purines; Pyrimidines | 2015 |
Distinct Metabolomic Profiles of Papillary Thyroid Carcinoma and Benign Thyroid Adenoma.
Topics: Adenoma; Adult; Amino Acids; Carbon; Carcinoma, Papillary; Chromatography, Liquid; Female; Gas Chromatography-Mass Spectrometry; Humans; Male; Mass Spectrometry; Metabolic Networks and Pathways; Metabolome; Metabolomics; Middle Aged; Neoplasm Staging; Purines; Pyrimidines; Thyroid Neoplasms | 2015 |
Interaction preferences between nucleobase mimetics and amino acids in aqueous solutions.
Topics: Amino Acids; Hydrophobic and Hydrophilic Interactions; Molecular Dynamics Simulation; Proteins; Purines; Pyrimidines; RNA, Messenger | 2015 |
Direct One-Pot Synthesis of Nucleosides from Unprotected or 5-O-Monoprotected D-Ribose.
Topics: Glycosylation; Molecular Structure; Nucleosides; Purines; Pyrimidines; Ribose | 2015 |
Applying Thymine Isostere 2,4-Difluoro-5-Methylbenzene as a NMR Assignment Tool and Probe of Homopyrimidine/Homopurine Tract Structural Dynamics.
Topics: Base Sequence; Magnetic Resonance Imaging; Nucleic Acid Conformation; Oligonucleotides; Purines; Pyrimidines; RNA; Saccharomyces cerevisiae; TATA Box; TATA-Box Binding Protein | 2016 |
Optimization of High Performance Liquid Chromatography Method for Simultaneous Determination of Some Purine and Pyrimidine Bases.
Topics: Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Purines; Pyrimidines | 2016 |
The Biosynthesis of the Pyrimidine Moiety of Thiamin in Halobacterium salinarum.
Topics: Biosynthetic Pathways; Escherichia coli; Glycine; Halobacterium salinarum; Histidine; Purines; Pyridoxine; Pyrimidines; Ribonucleotides; Saccharomyces cerevisiae; Thiamine; Thiazoles | 2016 |
Sinorhizobium fredii HH103 Invades Lotus burttii by Crack Entry in a Nod Factor-and Surface Polysaccharide-Dependent Manner.
Topics: Bacterial Proteins; Host Specificity; Lotus; Mutation; Phenotype; Plant Root Nodulation; Plant Roots; Polysaccharides, Bacterial; Purines; Pyrimidines; Sinorhizobium fredii; Symbiosis | 2016 |
The Role of Unconventional Hydrogen Bonds in Determining BII Propensities in B-DNA.
Topics: Base Sequence; Computer Simulation; Databases, Factual; DNA; DNA, B-Form; Hydrogen; Hydrogen Bonding; Models, Molecular; Molecular Dynamics Simulation; Molecular Sequence Data; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Purines; Pyrimidines | 2017 |
Fecal microbiota signatures of adult patients with different types of short bowel syndrome.
Topics: Adult; Amino Acids, Aromatic; Amino Acids, Branched-Chain; Case-Control Studies; Citric Acid Cycle; Dysbiosis; Feces; Female; Gastrointestinal Microbiome; Humans; Intestinal Mucosa; Intestines; Lactobacillus; Male; Middle Aged; Prospective Studies; Purines; Pyrimidines; Short Bowel Syndrome | 2017 |
CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells.
Topics: Ammonia; AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Animals; Bicarbonates; Carbamoyl-Phosphate Synthase (Ammonia); Carbamyl Phosphate; Carcinoma, Non-Small-Cell Lung; Cell Death; Cell Proliferation; DNA; DNA Damage; DNA Replication; DNA-Directed DNA Polymerase; Female; Gene Silencing; Humans; Lung Neoplasms; Male; Metabolomics; Mice; Mitochondria; Nitrogen; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins p21(ras); Purines; Pyrimidines; S Phase; Transcription, Genetic; Xenograft Model Antitumor Assays | 2017 |
iTRAQ-Based Proteomic Analysis of Neonatal Kidney from Offspring of Protein Restricted Rats Reveals Abnormalities in Intraflagellar Transport Proteins.
Topics: Animals; Animals, Newborn; Carrier Proteins; Databases, Protein; Diet, Protein-Restricted; Down-Regulation; Fetal Growth Retardation; Histone-Lysine N-Methyltransferase; Histones; Kidney; Oxidative Phosphorylation; Proteome; Proteomics; Purines; Pyrimidines; Rats; Rats, Wistar; TRPP Cation Channels; Up-Regulation | 2017 |
Purine- and pyrimidine-triple-helix-forming oligonucleotides recognize qualitatively different target sites at the ribosomal DNA locus.
Topics: Animals; Base Pairing; Binding Sites; DNA; DNA, Ribosomal; Electrophoretic Mobility Shift Assay; Humans; Mice; Oligonucleotides; Point Mutation; Promoter Regions, Genetic; Purines; Pyrimidines; Regulatory Sequences, Nucleic Acid | 2018 |
Theoretical characterization of sulfur-to-selenium substitution in an emissive RNA alphabet: impact on H-bonding potential and photophysical properties.
Topics: Base Pairing; Hydrogen Bonding; Models, Molecular; Nucleic Acid Conformation; Purines; Pyrimidines; RNA; Selenium; Sulfur; Thermodynamics | 2018 |
Prophylactic ketamine alters nucleotide and neurotransmitter metabolism in brain and plasma following stress.
Topics: Animals; Brain; Fear; Ketamine; Learning; Male; Metabolome; Mice, 129 Strain; Neurotransmitter Agents; Psychotropic Drugs; Purines; Pyrimidines; Stress, Psychological | 2018 |
Why are Hoogsteen base pairs energetically disfavored in A-RNA compared to B-DNA?
Topics: Base Pairing; DNA; DNA, B-Form; Energy Metabolism; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Models, Molecular; Nucleic Acid Conformation; Purines; Pyrimidines; RNA; Thermodynamics | 2018 |
Crystal structures of disordered Z-type helices.
Topics: Base Sequence; Crystallization; Crystallography, X-Ray; Databases, Nucleic Acid; DNA; Models, Molecular; Nucleic Acid Conformation; Purines; Pyrimidines | 2019 |
Preoperative Metabolic Signatures of Prostate Cancer Recurrence Following Radical Prostatectomy.
Topics: Amino Acids; Big Data; Chromatography, Liquid; Citric Acid Cycle; Glucose; Humans; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Metabolomics; Middle Aged; Neoplasm Recurrence, Local; Preoperative Period; Prostatectomy; Prostatic Neoplasms; Purines; Pyrimidines; Tryptophan | 2019 |
Establishment of a high throughput-screening system for nucleoside deoxyribosyltransferase II mutant enzymes with altered substrate specificity.
Topics: Catalysis; Catalytic Domain; Enzyme Assays; Escherichia coli; Gene Expression Regulation, Enzymologic; High-Throughput Screening Assays; Lactobacillus helveticus; Mutagenesis, Site-Directed; Mutant Proteins; Nucleosides; Pentosyltransferases; Protein Engineering; Purines; Pyrimidines; Structure-Activity Relationship; Substrate Specificity | 2019 |
Topics: Animals; Bacterial Proteins; Cattle; Corynebacterium; Evolution, Molecular; Gene Transfer, Horizontal; Genome Size; Genome, Bacterial; Genomics; Metabolic Networks and Pathways; Protein Interaction Maps; Purines; Pyrimidines; Staphylococcus aureus; Tenericutes; Ureaplasma; Virulence | 2019 |
Self-assemblies of nucleolipid supramolecular synthons show unique self-sorting and cooperative assembling process.
Topics: Crystallography, X-Ray; Lipids; Nucleic Acids; Purines; Pyrimidines | 2019 |
The ReFRAME library as a comprehensive drug repurposing library to identify mammarenavirus inhibitors.
Topics: A549 Cells; Animals; Antiviral Agents; Apoptosis; Arenaviridae; Arenaviridae Infections; Chlorocebus aethiops; Databases, Pharmaceutical; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Repositioning; Electron Transport Complex III; HEK293 Cells; Humans; Interferons; Junin virus; Lassa virus; Lymphocytic choriomeningitis virus; Proto-Oncogene Proteins c-bcl-2; Purines; Pyrimidines; Vero Cells; Virus Replication | 2019 |
Nucleotide Metabolism in Plants.
Topics: Models, Biological; Nucleotides; Plants; Purines; Pyrimidines | 2020 |
Single-Molecule Kinetics Show DNA Pyrimidine Content Strongly Affects RNA:DNA and TNA:DNA Heteroduplex Dissociation Rates.
Topics: DNA; Kinetics; Nucleic Acid Heteroduplexes; Nucleic Acid Hybridization; Purines; Pyrimidines; RNA; Thermodynamics | 2020 |
Novel pathways of HIV latency reactivation revealed by integrated analysis of transcriptome and target profile of bryostatin.
Topics: Bryostatins; CD4-Positive T-Lymphocytes; Cell Cycle Checkpoints; HIV Infections; HIV-1; Humans; Protein Kinase C; Purines; Pyrimidines; Signal Transduction; Transcriptome; Tumor Suppressor Protein p53; Up-Regulation; Virus Latency | 2020 |
Ligand Binding Mechanism and Its Relationship with Conformational Changes in Adenine Riboswitch.
Topics: Adenine; Bacterial Proteins; Guanine; Ligands; Models, Molecular; Molecular Dynamics Simulation; Mutation; Nucleic Acid Conformation; Purines; Pyrimidines; Riboswitch | 2020 |
Recent updates on purine and pyrimidine metabolism in physiological and pathological settings.
Topics: Disease; Humans; Purines; Pyrimidines | 2020 |
Metabolic basis of neuronal vulnerability to ischemia; an in vivo untargeted metabolomics approach.
Topics: Animals; Apoptosis; Brain Ischemia; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Chromatography, Liquid; Gene Expression Regulation; Humans; Ischemic Attack, Transient; Mass Spectrometry; Metabolomics; Neurons; Purines; Pyrimidines; Rats; Signal Transduction | 2020 |
A doubly auxotrophic CHO-K1 cell line for the production of recombinant monoclonal antibodies.
Topics: Animals; Antibodies, Monoclonal; Cell Line; CHO Cells; Cricetinae; Cricetulus; CRISPR-Cas Systems; Gene Knockout Techniques; Genetic Engineering; Purines; Pyrimidines; Recombinant Proteins; Transfection | 2020 |
Effect of congenital adrenal hyperplasia treated by glucocorticoids on plasma metabolome: a machine-learning-based analysis.
Topics: Adrenal Hyperplasia, Congenital; Adult; Area Under Curve; Case-Control Studies; Female; Glucocorticoids; Humans; Hydrocortisone; Indoleamine-Pyrrole 2,3,-Dioxygenase; Machine Learning; Male; Metabolome; Metabolomics; Purines; Pyrimidines; ROC Curve; Young Adult | 2020 |
Integrated Proteomics and Metabolomics Reveal the Mechanism of Nephrotoxicity Induced by Triptolide.
Topics: Amino Acids; Animals; Diterpenes; Epoxy Compounds; Glycerol; Kidney; Kidney Diseases; Male; Metabolomics; Phenanthrenes; Phospholipids; Proteomics; Purines; Pyrimidines; Rats, Wistar; Sphingolipids | 2020 |
Aqueous recognition of purine and pyrimidine bases by an anthracene-based macrocyclic receptor.
Topics: Anthracenes; Macrocyclic Compounds; Models, Molecular; Molecular Structure; Purines; Pyrimidines; Water | 2020 |
Methotrexate impacts conserved pathways in diverse human gut bacteria leading to decreased host immune activation.
Topics: Animals; Arthritis, Rheumatoid; Autoimmune Diseases; Bacteria; Female; Gastrointestinal Microbiome; Gastrointestinal Tract; Humans; Metabolomics; Methotrexate; Mice; Mice, Inbred C57BL; Phylogeny; Purines; Pyrimidines; RNA, Ribosomal, 16S; Tetrahydrofolate Dehydrogenase; Transcriptome | 2021 |
TOR coordinates nucleotide availability with ribosome biogenesis in plants.
Topics: Arabidopsis; Arabidopsis Proteins; Cytosol; Gene Silencing; Genes, Plant; Nicotiana; Nucleotides; Phosphatidylinositol 3-Kinases; Phosphorus; Plant Cells; Plant Development; Purines; Pyrimidines; Ribosomes; Transcriptome | 2021 |
Hydroxyurea Induces a Stress Response That Alters DNA Replication and Nucleotide Metabolism in Bacillus subtilis.
Topics: Bacillus subtilis; Bacterial Proteins; DNA Damage; DNA Replication; Hydroxyurea; Nucleotides; Operon; Purines; Pyrimidines; Ribonucleotide Reductases | 2021 |
Metabolomic and transcriptomic analysis reveals endogenous substrates and metabolic adaptation in rats lacking Abcg2 and Abcb1a transporters.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; Brain; Gene Expression Profiling; Gene Knockout Techniques; Histidine; Kidney; Liver; Male; Metabolic Clearance Rate; Metabolomics; Purines; Pyrimidines; Rats; Rats, Transgenic | 2021 |
Comprehensive characterization of purine and pyrimidine transport activities in Trichomonas vaginalis and functional cloning of a trichomonad nucleoside transporter.
Topics: Biological Transport; Cloning, Molecular; Humans; Kinetics; Nucleoside Transport Proteins; Protozoan Proteins; Purines; Pyrimidines; Trichomonas Infections; Trichomonas vaginalis | 2021 |