purine has been researched along with pemetrexed in 3 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (33.33) | 18.2507 |
2000's | 2 (66.67) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Chen, VJ; Gates, SB; Habeck, LL; Mendelsohn, LG; Shackelford, KA; Shih, C | 1 |
Chattopadhyay, S; Goldman, ID; Hanscom, M; Zhang, S; Zhao, R | 1 |
Schultz, RM | 1 |
2 review(s) available for purine and pemetrexed
Article | Year |
---|---|
Enzyme inhibition, polyglutamation, and the effect of LY231514 (MTA) on purine biosynthesis.
Topics: Animals; Antimetabolites, Antineoplastic; Enzyme Inhibitors; Folic Acid Antagonists; Glutamates; Guanine; Humans; Methotrexate; Pemetrexed; Peptide Synthases; Polyglutamic Acid; Purines; Tetrahydrofolates | 1999 |
Preclinical development of Alimta (Pemetrexed, LY231514), a multitargeted antifolate.
Topics: Animals; Antineoplastic Agents; Biological Transport; Drug Resistance, Neoplasm; Folic Acid Antagonists; Glutamates; Guanine; Humans; Neoplasms; Pemetrexed; Purines; Thymidylate Synthase | 2005 |
1 other study(ies) available for purine and pemetrexed
Article | Year |
---|---|
Loss of reduced folate carrier function and folate depletion result in enhanced pemetrexed inhibition of purine synthesis.
Topics: Animals; Blotting, Western; Cattle; Cell Division; Cell Line, Tumor; Culture Media; Dose-Response Relationship, Drug; Folic Acid; Folic Acid Antagonists; Glutamates; Guanine; HeLa Cells; Humans; Hypoxanthine; Leucovorin; Membrane Transport Proteins; Pemetrexed; Purines; Reduced Folate Carrier Protein; Serum; Thymidylate Synthase; Thymine | 2005 |