purine and mercaptopurine

purine has been researched along with mercaptopurine in 137 studies

Research

Studies (137)

TimeframeStudies, this research(%)All Research%
pre-1990131 (95.62)18.7374
1990's0 (0.00)18.2507
2000's1 (0.73)29.6817
2010's5 (3.65)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bökkerink, JP; De Abreu, RA; De Bruyn, CH; De Vaan, GA; Lippens, RJ; Schouten, TJ; Van Laarhoven, JP1
Ahment, K; Bokkerink, JP; Brouwer, C; De Abreu, RA; Keizer-Garritsen, JJ; Lambooy, LH; Trijbels, FJ1
CLARKE, DA; ELION, GB; HITCHINGS, GH; PHILIPS, FS; STERNBERG, SS; STOCK, CC1
ELION, GB; HITCHINGS, GH; SINGER, S2
BURCHENAL, JH; CRAVER, LF; DARGEON, HW; ELLISON, RR; KARNOFSKY, DA; LEONE, LA; MURPHY, ML; RHOADS, CP; SYKES, MP; TAN, TC1
BERNARD, J; DELTOUR, G1
LAW, LW1
AGGELER, PM; FEICHTMEIR, TV; HALL, BE; RICHARDS, MD; WILLETT, FM1
SCHMIDT, KH1
ELION, GB; HITCHINGS, GH; SKIPPER, HE; THOMSON, JR1
BURCHENAL, JH; ELLISON, RR; KARNOFSKY, DA; MERMANN, AC; MURPHY, ML; RHOADS, CP; SYKES, MP; TAN, CT; YUCEOGLU, M1
BURCHENAL, JH; RHOADS, CP1
BERNARD, J1
GOLDIN, A1
SANSONE, G1
DENNIS, D; GOLDIN, A; GREENHOUSE, SW; HUMPHREYS, SR; MANTEL, N; VENDITTI, JM2
ATWATER, J; GRUENSTEIN, M; SHAY, H1
MAZIMA, K; MIZUNOE, S; NOMURA, T; YAMAMOTO, S1
HAYHOE, FG1
FRIEDKIN, M1
MARINHO, HM1
HALL, SC; HOOKER, JW; POWELL, LW1
GASSER, C; HITZIG, W1
LENHARTZ, H1
FERNANDES, JF; LEPAGE, GA; LINDNER, A1
BECK, RE; MOFFAT, RG; PERRY, WH; WHITELAW, DM1
GHARPURE, VV; KARAMCHANDANI, PV; NAIDU, VR1
BERMAN, L; MOYNIHAN, JW1
BOUVIER, C; DUBOIS-FERRIERE, H; HAUSSER, A; KALACI, J; SORG, D; VAUTHIER, J; ZUMSTEIN, P1
REMY, D1
FITZPATRICK, MM; GREIG, HB; LAIRD, MH; METZ, J; ZENTKOWSKY, D1
GAVOSTO, F; PILERI, A; VERGNANO, F1
DEYSSON, G; DEYSSON, M; TRUHAUT, R1
CLARKE, DA; ELION, GB; HITCHINGS, GH; STOCK, CC1
LOO, TL; MICHAEL, ME1
FEIGELSON, P; ULTMANN, JE2
LEPAGE, GA; SARTORELLI, AC1
OLSSON, G1
DUGGAN, DE; TITUS, E1
JONES, M; LEPAGE, GA1
BIEBER, S; ELION, GB; HITCHINGS, GH1
CALLAHAN, SW; ELION, GB; HITCHINGS, GH; RUNDLES, RW1
JAFFE, JJ; MAUTNER, HG1
HOLLAND, JF; SELAWRY, OS1
SELAWRY, OS1
FREI, E; GOLDIN, A; VENDITTI, JM1
HALL, RP1
LEONARD, EO; McMURTRAY, TR; ORME-JOHNSON, WH; SHIVE, W; SKINNER, CG1
DOYLE, RT; KODLIN, D; RIVERS, SL; WHITTINGTON, RM2
ALEXANDRE, GP; CALNE, RY; MURRAY, JE1
CALNE, RY1
COULTAS, MK; HUTCHISON, DJ1
GARRISON, FE; HOBSON, JB; ITOGA, T; LASZLO, J; RUNDLES, RW1
NOELL, CW; ROBINS, RK1
JEFFREY, JJ; SCHANKER, LS; TOCCO, DJ1
CALLAHAN, S; ELION, GB; HITCHINGS, GH; RUNDLES, RW1
HITCHINGS, GH1
BARKER, TL; BENNETT, LL; GOLDEN, J; SIMPSON, L1
BERGMANN, F; BURGER-RACHAMIMOV, H; TAMARI, M1
FRANC, Z; FRANCOVA, V; JELINEK, V1
BOOTH, BA; SARTORELLI, AC1
MAGASANIK, B; ZIMMERMAN, EF1
NANETTI, L; VALLINI, R1
HENDERSON, JF; MAZEL, P1
WOODLIFF, HJ1
ANDERSON, EP; BROCKMAN, RW1
BALIS, ME; SALSER, JS1
FREI, E; GOLD, GL; HALL, T; HOLLAND, JF; KRANT, M; MILLER, SO; REGELSON, W1
CUTTS, JH1
BENNETT, KJ; GILES, WG; HANSEN, HJ; NADLER, SB; VANDEVOORDE, JP1
BENDER, HS; DYER, E1
ASHTON, DM; GILBERT, WR; MCCOLLISTER, RJ; WYNGAARDEN, JB1
BRAGONIER, JR; CARVER, MJ; ROESKY, N1
NAGEL, R1
BIEBER, AL; BOOTH, BA; SARTORELLI, AC; UPCHURCH, HF1
LEVY, RN; RUOHANI, J; SAWITSKY, A1
GUTHRIE, R; LU, WC1
JUNGA, IG; LEPAGE, GA1
KORNACKA, L; MALEC, J; WOJNAROWSKA, M; ZAKRZEWSKI, K1
BICHEL, J; BJORNJENSEN, K; THORLING, EB1
ATKINSON, MR; MURRAY, AW1
BROCKMAN, RW; CHUMLEY, S1
OEHME, J1
BIEBER, R; BIEBER, S; HITCHINGS, GH1
HUTCHISON, DJ1
THIERSCH, JB1
BIESELE, JJ2
CLARKE, DA; PHILIPS, FS; STERNBERG, SS; STOCK, CC1
BOYLE, PJ; LAW, LW; TAORMINA, V1
SKIPPER, HE2
GELLHORN, A; HIRSCHBERG, E; KELLS, A; MURRAY, MR; PETERSON, ER1
CLARKE, DA; HAMILTON, S; PHILIPS, FS; STERNBERG, SS1
ALBERSTADT, N; BURCHENAL, JH; ELLISON, RR; KARNOFSKY, DA; KRAKOFF, I; MERMANN, AC; MURPHY, ML; MYERS, WP; SYKES, MP; TAN, TC; YUCEOGLU, M1
BROSS, ID1
FEICHTMEIR, TV; HALL, BE; RICHARDS, MD; WILLETT, FM1
BERNARD, J; SELIGMANN, M1
JIMENEZ DE ASUA, F1
BOURONCLE, B; DOAN, CA; WISEMAN, K1
FARBER, S1
PIERCE, M1
CRAGO, JA; RUNDLES, RW1
GELLHORN, A; HYMAN, GA; WOLFF, JA1
BETHELL, FH; THOMPSON, DS1
FOUNTAIN, JR2
DAMESHEK, W1
LEE, SL; ROSENTHAL, N; ROSENTHAL, RL1
SYDENSTRICKER, VP1
RICE, EC1
HILL, JM; LAJOUS, J1
LOZNER, EL1
NEWTON, WA1
REAM, CR; SAWITSKY, A1
COOPER, WM; GAFFNEY, PC1
DEMARSH, QB1
DEAMER, WC; GELLERT, SA; LEONARD, ME; LI, JG; METTIER, SR; PETRAKIS, NL; WOOD, DA1
WILSON, SJ1
BORRONE, C; ZUNIN, C1
ROUQUES, L1
LENZI, G1
LIEBERMAN, I; OVE, P1
FRONTINO, G; KATO, R; VASSANELLI, P1
KELLEY, GG; MONTGOMERY, JA; WHEELER, GP1
HALL, J; OZOA, N; PIERCE, M1
Dalhoff, K; Hedeland, RL; Hvidt, K; Lausen, B; Nersting, J; Rosthøj, S; Schmiegelow, K1
Coulthard, SA; Hall, AG; Hogarth, LA; Jakobsen-Falk, I; Lindqvist-Appell, M; Redfern, CP; Skoglund, K; Taylor, GA; Vikingsson, S1
de Boer, NK; de Meij, T; van Bodegraven, AA1
Bai, Y; Chen, H; Chen, J; Chen, S; Chen, Y; Ding, J; Ding, L; Du, A; Ferrando, A; Gu, L; Huang, X; Jin, L; Kang, H; Kirschner-Schwabe, R; Li, B; Li, H; Li, W; Liang, H; Lu, G; Lu, H; Ma, X; Shen, S; Tang, J; Tzoneva, G; von Stackelberg, A; Wang, S; Wu, T; Yang, JJ; Yang, M; Zhang, J; Zhou, BB1
Ambesi-Impiombato, A; Basso, G; Dieck, CL; Ferrando, AA; Gastier-Foster, JM; Iacobucci, I; Kato, M; Khiabanian, H; Kirschner-Schwabe, R; Koh, K; Loh, ML; Madubata, CJ; Mullighan, CG; Oshima, K; Paganin, M; Rabadan, R; Sánchez-Martín, M; Sulis, ML; Tzoneva, G; Waanders, E; Yu, J1

Reviews

3 review(s) available for purine and mercaptopurine

ArticleYear
6-mercaptopurine: efficacy and bone marrow toxicity in childhood acute lymphoblastic leukemia. Association with low (thio)purine enzyme activity.
    Advances in experimental medicine and biology, 2000, Volume: 486

    Topics: Antimetabolites, Antineoplastic; Bone Marrow; Child; Humans; Mercaptopurine; Methyltransferases; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Purines

2000
BIOCHEMISTRY OF CANCER (METABOLIC ASPECTS).
    Annual review of biochemistry, 1963, Volume: 32

    Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Azaguanine; Azaserine; Carcinoma, Ehrlich Tumor; DNA; DNA, Neoplasm; Floxuridine; Fluorouracil; Folic Acid; Glutamine; Leukemia L1210; Mercaptopurine; Methotrexate; Mitomycin; Neoplasms; Neoplasms, Experimental; Pharmacology; Purines; Puromycin; Pyrimidines; Research; RNA; RNA, Neoplasm; Thioguanine; Thiouracil

1963
[THE PRESENT STATUS OF KIDNEY TRANSPLANTATION].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 1964, Volume: 35

    Topics: Azathioprine; Dactinomycin; Immune Tolerance; Immunity; Immunosuppressive Agents; Kidney Transplantation; Mercaptopurine; Purines; Radiation Effects; Research; Transplantation Immunology; Transplantation, Heterologous; Transplantation, Homologous; Twins

1964

Other Studies

134 other study(ies) available for purine and mercaptopurine

ArticleYear
[6-Mercaptopurine and methotrexate, rational use in sight after 35 years?].
    Tijdschrift voor kindergeneeskunde, 1984, Volume: 52, Issue:4

    Topics: Animals; Child; Dogs; Half-Life; Humans; Infusions, Parenteral; Leukemia, Lymphoid; Lymphocytes; Mercaptopurine; Methotrexate; Purines; Pyrimidines

1984
6-Mercaptopurine: effects in mouse sarcoma 180 and in normal animals.
    Cancer research, 1953, Volume: 13, Issue:8

    Topics: Animals; Mercaptopurine; Mice; Purines; Sarcoma 180; Sarcoma, Experimental

1953
The purine metabolism of a 6-mercaptopurine-resistant Lactobacillus casei.
    The Journal of biological chemistry, 1953, Volume: 204, Issue:1

    Topics: Lacticaseibacillus casei; Lactobacillus; Mercaptopurine; Metabolic Networks and Pathways; Purines

1953
Clinical evaluation of a new antimetabolite, 6-mercaptopurine, in the treatment of leukemia and allied diseases.
    Blood, 1953, Volume: 8, Issue:11

    Topics: Antimetabolites; Leukemia; Mercaptopurine; Purines

1953
[New therapy of leukoses; triethylene phosphoramide; G. T. 41 (myleran); 6-mercaptopurine; beta-mercaptoethylamine; massive doses of cortisone].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1953, Nov-02, Volume: 29, Issue:67

    Topics: Busulfan; Cortisone; Cysteamine; Ethylamines; Leukemia; Mercaptopurine; Phosphoramides; Phosphorus; Phosphorus, Dietary; Purines; Triethylenephosphoramide

1953
Resistance in leukemic cells to an adenine antagonist, 6-mercaptopurine.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1953, Volume: 84, Issue:2

    Topics: Adenine; Animals; Humans; Leukemia, Experimental; Mercaptopurine; Purines

1953
Evaluation of 6-mercaptopurine in the treatment of leukemia; a preliminary report.
    Stanford medical bulletin, 1953, Volume: 11, Issue:4

    Topics: Leukemia; Mercaptopurine; Purines

1953
[Experimental and comparative results with triethylene melamine, N,N',N"-triethylene phosphoramide and 6-mercaptopurine].
    Arzneimittel-Forschung, 1954, Volume: 4, Issue:3a

    Topics: Animals; Leukemia; Leukemia, Experimental; Mercaptopurine; Mitosis; Neoplasms, Experimental; Phosphoramides; Poisons; Purines; Triethylenemelamine; Triethylenephosphoramide

1954
Observations on the anticancer activity of 6-mercaptopurine.
    Cancer research, 1954, Volume: 14, Issue:4

    Topics: Animals; Mercaptopurine; Neoplasms, Experimental; Purines

1954
Clinical evaluation of 6-mercaptopurine in the treatment of leukemia.
    The American journal of the medical sciences, 1954, Volume: 228, Issue:4

    Topics: Leukemia; Mercaptopurine; Purines

1954
Clinical evaluation of 6-mercaptopurine in the treatment of leukemia.
    Transactions of the Association of American Physicians, 1954, Volume: 67

    Topics: Leukemia; Mercaptopurine; Purines

1954
[6-mercaptopurine].
    Le Sang, 1954, Volume: 25, Issue:8

    Topics: Mercaptopurine; Metabolism; Purines

1954
Demonstration of protection against the lethal toxicity of 6-mercaptopurine in mice.
    Journal of the National Cancer Institute, 1954, Volume: 14, Issue:6

    Topics: Animals; Mercaptopurine; Mice; Nucleotides; Purines

1954
[Atypical myeloerythropoiesis with giant plurinucleated elements in child with Hodgkin's disease treated with 6-mercaptopurine; preventive note].
    Minerva medica, 1954, Nov-28, Volume: 45, Issue:95

    Topics: Child; Hematopoiesis; Hodgkin Disease; Humans; Mercaptopurine; Purines

1954
An investigation into the synergistic antileukemic action of amethopterin and 6-mercaptopurine in mice.
    Journal of the National Cancer Institute, 1955, Volume: 16, Issue:1

    Topics: Animals; Folic Acid Antagonists; Leukemia, Experimental; Mercaptopurine; Methotrexate; Mice; Purines

1955
6-MERCAPTOPURINE and nucleic acid synthesis.
    Nutrition reviews, 1955, Volume: 13, Issue:8

    Topics: Humans; Mercaptopurine; Nucleic Acids; Purines

1955
Effect of triethylene thiophosphoramide and 6-mercaptopurine in chronic myelogenous and in an acute leukemia in rats.
    Acta - Unio Internationalis Contra Cancrum, 1955, Volume: 11, Issue:2

    Topics: Animals; Leukemia; Leukemia, Experimental; Mercaptopurine; Phosphorus; Purines; Rats; Thiotepa

1955
[Effect of 6-mercaptopurine on inplanted malignant tumor of animal].
    Gan, 1955, Volume: 46, Issue:2-3

    Topics: Animals; Mercaptopurine; Neoplasms; Neoplasms, Experimental; Purines

1955
6-Mercaptopurine in acute leukaemia.
    Lancet (London, England), 1955, Oct-29, Volume: 269, Issue:6896

    Topics: Acute Disease; Leukemia; Mercaptopurine; Purines

1955
The enzymic synthesis of 6-mercaptopurine deoxyriboside.
    Biochimica et biophysica acta, 1955, Volume: 18, Issue:3

    Topics: Mercaptopurine; Purines

1955
[A synthetic antileukemic agent, 6-mercaptopurine].
    Medicina, cirurgia, farmacia, 1955, Issue:232

    Topics: Antineoplastic Agents; Leukemia; Mercaptopurine; Purines

1955
Acute monocytic leukemia: report of a case treated with cortisone and 6-mercaptopurine.
    Southern medical journal, 1956, Volume: 49, Issue:1

    Topics: Cortisone; Leukemia; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Mercaptopurine; Purines

1956
[6-Mercaptopurine (purinethol) in the treatment of leukemia in children; comparison with cortisone and aminopterin].
    Helvetica paediatrica acta, 1955, Volume: 10, Issue:5

    Topics: Aminopterin; Child; Cortisone; Humans; Infant; Leukemia; Mercaptopurine; Purines

1955
[Purinethol treatment of acute myeloblastic leukemia].
    Therapie der Gegenwart, 1955, Volume: 94, Issue:9

    Topics: Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Mercaptopurine; Purines

1955
The influence of azaserine and 6-mercaptopurine on the in vivo metabolism of ascites tumor cells.
    Cancer research, 1956, Volume: 16, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Ascites; Azaserine; Carcinoma, Ehrlich Tumor; Mercaptopurine; Neoplasms; Purines

1956
Acute leukaemia in adults treated with 6-mercaptopurine.
    Canadian Medical Association journal, 1956, Mar-15, Volume: 74, Issue:6

    Topics: Acute Disease; Leukemia; Mercaptopurine; Purines

1956
6-Mercaptopurine in acute lymphocytic leukaemia.
    Journal of the Indian Medical Association, 1956, Feb-01, Volume: 26, Issue:3

    Topics: Humans; Leukemia; Leukemia, Lymphoid; Mercaptopurine; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Purines

1956
Acute leukemia in adults; treatment with the combined use of ACTH or cortisone and 6 mercaptopurine.
    Journal - Michigan State Medical Society, 1956, Volume: 55, Issue:3

    Topics: Acute Disease; Adrenocorticotropic Hormone; Cortisone; Leukemia; Mercaptopurine; Purines

1956
[Cortisone in massive doses and 6-mercaptopurine in the treatment of acute leucemias in adult; possibility of producing successive remissions].
    Praxis, 1956, Feb-02, Volume: 45, Issue:5

    Topics: Cortisone; Leukemia; Mercaptopurine; Neoplasms; Purines

1956
[6-Mercaptopurine (purinethol) in therapy of myeloid leukemia].
    Deutsche medizinische Wochenschrift (1946), 1956, Mar-02, Volume: 81, Issue:9

    Topics: Humans; Leukemia; Leukemia, Myeloid; Mercaptopurine; Purines

1956
Chemotherapy of leukaemia. II. 6-Mercaptopurine (purinethol) in the treatment of acute leukaemia and some other neoplastic diseases of the reticuloendothelial system.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1956, Apr-14, Volume: 30, Issue:15

    Topics: Leukemia; Mercaptopurine; Mononuclear Phagocyte System; Neoplasms; Purines

1956
[Experimental research on the mechanism of action of antipurines; influence of 6-mercaptopurine on nucleic acid of regenerated rat liver].
    Archivio per le scienze mediche, 1956, Volume: 101, Issue:6

    Topics: Animals; Liver; Mercaptopurine; Nucleic Acids; Purines; Rats

1956
[Effect of various purine antagonists (2-6-diaminopurine, 8-azaguanine and 6-mercaptopurine) on plant cell division].
    Bulletin de la Societe de chimie biologique, 1956, Jun-21, Volume: 38, Issue:2-3

    Topics: 2-Aminopurine; Azaguanine; Cell Division; Mercaptopurine; Plants; Purines

1956
Structure-activity relationships among purines related to 6-mercaptopurine.
    Cancer research, 1958, Volume: 18, Issue:4

    Topics: Mercaptopurine; Purines; Structure-Activity Relationship

1958
A colorimetric method for the determination of certain purine antagonists.
    The Journal of biological chemistry, 1958, Volume: 232, Issue:1

    Topics: Antimetabolites; Colorimetry; Mercaptopurine; Purines

1958
The effects of 8-azaguanine and 6-mercaptopurine on purine catabolism in the rat.
    Cancer research, 1958, Volume: 18, Issue:11

    Topics: Animals; Azaguanine; Guanine; Mercaptopurine; Metabolic Networks and Pathways; Purines; Rats

1958
Metabolic effects of 6-thioguanine. II. Biosynthesis of nucleic acid purines in vivo and in vitro.
    Cancer research, 1958, Volume: 18, Issue:11

    Topics: In Vitro Techniques; Mercaptopurine; Metabolic Networks and Pathways; Nucleic Acids; Purines; Thioguanine

1958
[Acute leukemia in children treated with meticorten & purinethol].
    Svenska lakartidningen, 1959, Jan-30, Volume: 56, Issue:5

    Topics: Acute Disease; Child; Humans; Infant; Leukemia; Mercaptopurine; Prednisone; Purines

1959
6-Chloropurine and 6-chlorouric acid as substrates and inhibitors of purine-oxidizing enzymes.
    The Journal of biological chemistry, 1959, Volume: 234, Issue:8

    Topics: Mercaptopurine; Metabolic Networks and Pathways; Purines; Uric Acid

1959
Purinethiols as feedback inhibitors of purine synthesis in ascites tumor cells.
    Cancer research, 1961, Volume: 21

    Topics: Animals; Antineoplastic Agents; Ascites; Carcinoma, Ehrlich Tumor; Humans; Mercaptopurine; Purines; Sulfhydryl Compounds

1961
The effects of 8-azaguanine and 6-mercaptopurine on purine catabolism in the rat.
    Acta - Unio Internationalis Contra Cancrum, 1960, Volume: 16

    Topics: Animals; Antineoplastic Agents; Azaguanine; Mercaptopurine; Purines; Rats

1960
A summary of investigations with 2-amino-6-[(1-methyl-4-nitro-5-imidazolyl)thio]purine (B.W. 57-323) in animals.
    Cancer chemotherapy reports, 1960, Volume: 8

    Topics: Mercaptopurine; Purines

1960
The metabolism of 2-amino-6-[(1-methyl-4-nitro-5-imidazolyl)thio]purine (B.W. 57-323) in man.
    Cancer chemotherapy reports, 1960, Volume: 8

    Topics: Mercaptopurine; Purines

1960
A comparison of the biological properties of 6-selenopurine, 6-selenopurine ribonucleoside, and 6-mercaptopurine in mice.
    Cancer research, 1960, Volume: 20

    Topics: Animals; Mercaptopurine; Mice; Purines; Ribonucleosides; Selenium

1960
Tolerance to weekly doses of 2-amino-6-[(1-methyl-4-nitro-5-imidazolyl)thio]-purine (B.W. 57-323) in humans.
    Cancer chemotherapy reports, 1960, Volume: 8

    Topics: Drug Tolerance; Immune Tolerance; Mercaptopurine; Purines

1960
Effect of 2-amino-6-[(1-methyl-4-nitro-5-imidazolyl)thio]purine (imidazolylthioguanine; B.W. 57-323) on acute leukemia in man.
    Cancer chemotherapy reports, 1960, Volume: 8

    Topics: Acute Disease; Leukemia; Mercaptopurine; Purines

1960
The effectiveness of 2-amino-6-[(1-methyl-4-nitro-5-imidazolyl)thio] purine against transplantable mouse leukemia.
    Cancer chemotherapy reports, 1960, Volume: 8

    Topics: Animals; Leukemia; Leukemia, Experimental; Mercaptopurine; Purines

1960
Attempts to induce double resistance to drugs in the flagellate, Chilomonas paramecium.
    Archiv fur Mikrobiologie, 1962, Volume: 42

    Topics: Cryptophyta; Eukaryota; Humans; Mercaptopurine; Paramecium; Purines

1962
2-Hydroxy derivatives of some biologically active 6-(substituted) purines.
    Archives of biochemistry and biophysics, 1962, Volume: 99

    Topics: Mercaptopurine; Oxidoreductases; Purines

1962
Acute leukemia in the adult male. I. Comparative effect of 6-mercaptopurine and 6-chloropurine.
    Cancer, 1963, Volume: 16

    Topics: Acute Disease; Leukemia; Mercaptopurine; Purines

1963
Acute leukemia in the adult male. I. Comparative effect of 6-mercaptopurine and 6-chloropurine.
    Cancer chemotherapy reports, 1962, Volume: 18

    Topics: Acute Disease; Leukemia; Mercaptopurine; Purines

1962
A study of the effects of drugs in prolonging survival of homologous renal transplants in dogs.
    Annals of the New York Academy of Sciences, 1962, Oct-24, Volume: 99

    Topics: Animals; Cyclophosphamide; Dactinomycin; Dogs; Kidney; Kidney Transplantation; Mercaptopurine; Nitrogen Mustard Compounds; Purines; Radiation Effects

1962
Inhibition of the rejection of renal homografts in dogs by drugs.
    Annals of the Royal College of Surgeons of England, 1963, Volume: 32

    Topics: Allografts; Animals; Antineoplastic Agents; Cyclophosphamide; Dactinomycin; Dogs; Humans; Imidazoles; Kidney Transplantation; Mechlorethamine; Mercaptopurine; Purines; Radiation Effects; Transplantation, Homologous

1963
Metabolism of resistant mutants of Streptococcus faecalis. IV. Use of a biophotometer in growth-curve studies.
    Journal of bacteriology, 1962, Volume: 84

    Topics: Azaguanine; Drug Resistance, Microbial; Enterococcus faecalis; Mercaptopurine; Photometry; Purines

1962
Clinical and hematologic study of 6[(1-methyl-4-nitro-5-imidazolyl)thio]-purine (B.W.57-322) and related compounds.
    Cancer chemotherapy reports, 1961, Volume: 14

    Topics: Humans; Imidazoles; Mercaptopurine; Purines

1961
POTENTIAL PURINE ANTAGONISTS. XXXI. THE PREPARATION OF CERTAIN 9-ALKYL-2-AMINO-6-PURINETHIOLS AND RELATED DERIVATIVES AS ANTITUMOR AGENTS.
    Journal of medicinal and pharmaceutical chemistry, 1962, Volume: 5

    Topics: Adenocarcinoma; Antimetabolites; Antineoplastic Agents; Chemical Phenomena; Chemistry; Mercaptopurine; Pharmacology; Purines; Research; Sulfhydryl Compounds; Thioguanine

1962
INTERACTION OF PURINES WITH THE PYRIMIDINE TRANSPORT PROCESS OF THE SMALL INTESTINE.
    Biochemical pharmacology, 1963, Volume: 12

    Topics: Adenine; Caffeine; Carbon Isotopes; Guanine; Intestine, Small; Intestines; Mercaptopurine; Pharmacology; Physiology; Purines; Pyrimidines; Rats; Research; Theobromine; Theophylline; Uracil; Uric Acid; Xanthines

1963
RELATIONSHIP BETWEEN METABOLIC FATES AND ANTITUMOR ACTIVITIES OF THIOPURINES.
    Cancer research, 1963, Volume: 23

    Topics: Animals; Antineoplastic Agents; Mercaptopurine; Metabolism; Mice; Purines; Sulfhydryl Compounds; Sulfur Isotopes; Urine

1963
SUMMARY OF INFORMAL DISCUSSION ON THE ROLE OF PURINE ANTAGONISTS.
    Cancer research, 1963, Volume: 23

    Topics: Antimetabolites; Gout; Humans; Leukemia; Mercaptopurine; Pharmacology; Psoriasis; Purines; Pyrazoles; Pyrimidines

1963
THE PRIMARY SITE OF INHIBITION BY 6-MERCAPTOPURINE ON THE PURINE BIOSYNTHETIC PATHWAY IN SOME TUMORS IN VIVO.
    Cancer research, 1963, Volume: 23

    Topics: Animals; Biosynthetic Pathways; Carbon Isotopes; Carcinoma; Carcinoma, Ehrlich Tumor; DNA; DNA, Neoplasm; Formates; Glycine; Leukemia L1210; Mercaptopurine; Metabolism; Nucleotides; Purines; Research; RNA; RNA, Neoplasm; Sarcoma 180

1963
EVIDENCE FOR DIFFERENT ACTIVATION MECHANISMS IN THE OXIDATION OF 6-OXO- AND 6-THIOPURINES BY MAMMALIAN XANTHINE OXIDASE.
    Biochemical and biophysical research communications, 1963, Aug-01, Volume: 12

    Topics: Animals; Chemical Phenomena; Chemistry; Mammals; Mercaptopurine; Oxidation-Reduction; Oxidoreductases; Purines; Research; Xanthine Oxidase

1963
[RESORPTION, DISTRIBUTION IN THE TISSUES AND EXCRETORY ACTIVITY AFTER ADMINISTRATION OF S35-LABELLED-BUTHIOPURINE IN MICE].
    Ceskoslovenska farmacie, 1963, Volume: 12

    Topics: Animals; Feces; Mercaptopurine; Metabolism; Mice; Purines; Research; Sarcoma 180; Sulfur Isotopes; Urine

1963
GROWTH INHIBITION OF A SPECTRUM OF TRANSPLANTED MOUSE TUMORS BY COMBINATIONS OF INHIBITORS OF NUCLEIC ACID BIOSYNTHESIS AND ALKYLATING AGENTS.
    Cancer research, 1963, Volume: 23

    Topics: Alkylating Agents; Animals; Antineoplastic Agents; Azaguanine; Azaserine; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; DNA; DNA, Neoplasm; Fluorouracil; Idoxuridine; Liver Neoplasms; Lymphoma; Lymphoma, Non-Hodgkin; Mercaptopurine; Mice; Neoplasms, Experimental; Nitrogen Mustard Compounds; Nucleosides; Nucleotides; Purines; Research; RNA; RNA, Neoplasm; Sarcoma 180; Thioguanine; Uracil Mustard

1963
UTILIZATION AND INTERCONVERSION OF PURINE BASES AND RIBONUCLEOSIDES BY SALMONELLA TYPHIMURIUM.
    The Journal of biological chemistry, 1964, Volume: 239

    Topics: Adenine; Adenine Nucleotides; Carbon Isotopes; Chromatography; Culture Media; Guanine; Guanine Nucleotides; Histidine; Mercaptopurine; Metabolism; Nucleosides; Purines; Research; Ribonucleosides; Salmonella typhimurium; Spectrophotometry

1964
[PRESENT STATE OF ANTINEOPLASTIC CHEMOTHERAPY FROM THE PHARMACOLOGIC POINT OF VIEW].
    Minerva medica, 1963, Nov-03, Volume: 54

    Topics: Acridines; Antineoplastic Agents; Arsenicals; Azaguanine; Azaserine; Busulfan; Cell Division; Chloramines; Colchicine; Humans; Mercaptopurine; Pharmacology; Purines; Thiotepa; Triethylenemelamine

1963
DEMETHYLATION OF PURINE ANALOGS BY MICROSOMAL ENZYMES FROM MOUSE LIVER.
    Biochemical pharmacology, 1964, Volume: 13

    Topics: Animals; Antimetabolites; Caffeine; Carcinoma; Carcinoma, Ehrlich Tumor; Liver; Mercaptopurine; Metabolism; Mice; Purines; Pyrimidines; Research; Sulfhydryl Compounds; Theobromine; Theophylline

1964
IN-VITRO SENSITIVITY TESTS OF LEUKAEMIC CELLS TO CHEMOTHERAPEUTIC AGENTS.
    The Medical journal of Australia, 1964, Apr-04, Volume: 1

    Topics: Aminopterin; Animals; Antineoplastic Agents; Busulfan; Chlorambucil; Cyclophosphamide; Geriatrics; Histological Techniques; Hydrocortisone; Leukemia; Leukemia, Lymphoid; Leukocytosis; Mercaptopurine; Methotrexate; Mice; Polycythemia Vera; Purines; Research; Tissue Culture Techniques

1964
THE INTERCONVERSION OF PURINES BY TUMORS AND THE ACTION OF ANTI-PURINES.
    Acta - Unio Internationalis Contra Cancrum, 1964, Volume: 20

    Topics: Animals; Antineoplastic Agents; Aspartic Acid; Azaguanine; Carbon Isotopes; Glycine; Guanine Nucleotides; Imidazoles; Liver; Lyases; Mercaptopurine; Metabolism; Mice; Neoplasms, Experimental; Nucleotides; Pharmacology; Purines; Research; Sarcoma 180; Thioguanine

1964
COMPARATIVE CLINICAL TOXICITY OF 6-MERCAPTOPURINE (NSC-755)-1 AND 6-MERCAPTOPURINE RIBONUCLEOSIDE (NSC-4911)-2 ADMINISTERED INTRAVENOUSLY TO PATIENTS WITH ADVANCED CANCER.
    Cancer chemotherapy reports, 1964, Volume: 36

    Topics: Bone Marrow; Injections, Intravenous; Leukopenia; Mercaptopurine; Mice; Neoplasms; Nucleosides; Pharmacology; Purines; Pyrimidines; Research; Thioinosine; Thrombocytopenia; Toxicology

1964
EFFECTS OF OTHER AGENTS ON THE BIOLOGIC RESPONSES TO VINCALEUKOBLASTINE.
    Biochemical pharmacology, 1964, Volume: 13

    Topics: 2-Aminopurine; Aminopterin; Animals; Aspartic Acid; Azaguanine; Biological Products; Colchicine; Cortisone; Glutamates; Leukemia; Leukemia L1210; Leukemia, Experimental; Mercaptopurine; Methotrexate; Mice; Pharmacology; Purines; Research; Tryptophan; Vinblastine

1964
AZASERINE AND THIOPURINES. I. INHIBITION OF S-180 MOUSE TUMOR AND ANTIBODY SYNTHESIS.
    The Journal of laboratory and clinical medicine, 1964, Volume: 63

    Topics: Alkylating Agents; Animals; Antibody Formation; Antineoplastic Agents; Azaserine; Imidazoles; Mercaptopurine; Mice; Pharmacology; Purines; Rats; Research; Sarcoma 180; Tetanus Toxoid; Thioguanine; Toxicology

1964
DERIVATIVES OF PURINETHIOLS. PURINE THIOLCARBONATES AND RELATED COMPOUNDS.
    Journal of medicinal chemistry, 1964, Volume: 7

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carbonates; Chemistry, Pharmaceutical; Leukemia L1210; Mercaptopurine; Mice; Purines; Research; Sarcoma 180; Tissue Culture Techniques

1964
PSEUDOFEEDBACK INHIBITION OF PURINE SYNTHESIS BY 6-MERCAPTOPURINE RIBONUCLEOTIDE AND OTHER PURINE ANALOGUES.
    The Journal of biological chemistry, 1964, Volume: 239

    Topics: Adenine Nucleotides; Antimetabolites; Antineoplastic Agents; Azaguanine; Chromatography; Diphosphates; Enzyme Inhibitors; Glutamine; Mercaptopurine; Nucleotides; Purines; Pyrazoles; Pyrimidines; Research; Thioguanine; Transferases; Ultraviolet Rays

1964
TERATOGENESIS: EFFECTS OF SUBSTITUTED PURINES AND THE INFLUENCE OF 4-HYDROXYPYRAZOLOPYRIMIDINE IN THE RAT.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1964, Volume: 116

    Topics: Abnormalities, Drug-Induced; Adenine; Female; Mercaptopurine; Neoplasms; Neoplasms, Experimental; Pharmacology; Placenta; Pregnancy; Purines; Pyrazoles; Pyrimidines; Rats; Research; Teratogenesis; Thioguanine; Toxicology

1964
SOME METABOLIC EFFECTS EXERTED BY AZASERINE AND PURINE ANALOGS IN VIVO.
    Cancer research, 1964, Volume: 24

    Topics: Adenine; Amino Acids; Animals; Antimetabolites; Antineoplastic Agents; Azaserine; Carbon Isotopes; Glycine; Guanine; Mercaptopurine; Metabolism; Mice; Neoplasm Transplantation; Nucleotides; Pharmacology; Purines; Research; Sarcoma 180

1964
DRUG FEVER PRODUCED BY SIX-MERCAPTOPURINE.
    Annals of internal medicine, 1964, Volume: 61

    Topics: Adenine; Antineoplastic Agents; Drug Therapy; Fever; Hematocrit; Leukemia; Leukocyte Count; Mercaptopurine; Purines; Thioguanine; Toxicology

1964
ANTAGONISM BETWEEN PURINES IN PURINE-REQUIRING BACILLUS SUBTILIS MUTANTS.
    Archives of biochemistry and biophysics, 1964, Volume: 108

    Topics: 2-Aminopurine; Adenine; Adenine Nucleotides; Azaguanine; Bacillus subtilis; Guanine; Guanine Nucleotides; Hypoxanthines; Mercaptopurine; Metabolism; Mutation; Nucleosides; Nucleotides; Pharmacology; Purines; Research; Xanthines

1964
METABOLISM OF PURINE NUCLEOSIDE ANALOGS.
    Cancer research, 1965, Volume: 25

    Topics: Adenine; Animals; Antimetabolites; Guanine; Mercaptopurine; Metabolism; Mice; Neoplasms; Neoplasms, Experimental; Nucleosides; Purine Nucleosides; Purines; Research

1965
EFFECT OF PURINES AND SOME OF THEIR ANALOGUES ON PROTEIN AND RNA SYNTHESIS IN ISOLATED NUCLEI.
    Biochimica et biophysica acta, 1964, Dec-16, Volume: 91

    Topics: Antibody Formation; Antimetabolites; Antineoplastic Agents; Carbon Isotopes; Cell Nucleus; Cytosine; Guanine; Leucine; Leukocytes; Lysine; Mercaptopurine; Metabolism; Orotic Acid; Pharmacology; Proteins; Purines; Research; RNA; Thioguanine; Uracil; Uric Acid; Xanthines

1964
ON THE EFFECT OF BUTHIOPURINE IN ACUTE LEUKAEMIA.
    Neoplasma, 1964, Volume: 11

    Topics: Antineoplastic Agents; Drug Therapy; Humans; Leukemia; Leukemia, Myeloid; Mercaptopurine; Prognosis; Purines

1964
INHIBITION OF PRUINE PHOSPHORIBOSYLTRANSFERASES OF EHRLICH ASCITES-TUMOUR CELLS BY 6-MERCAPTOPURINE.
    The Biochemical journal, 1965, Volume: 94

    Topics: Adenine; Adenine Nucleotides; Adenosine Monophosphate; Animals; Ascites; Carcinoma, Ehrlich Tumor; Diphosphates; Electrophoresis; Enzyme Inhibitors; Glucosyltransferases; Guanine; Guanine Nucleotides; Hypoxanthines; Kinetics; Mercaptopurine; Nucleotides; Pharmacology; Purines; Research; Spectrophotometry; Transferases; Xanthines

1965
INHIBITION OF FORMYLGLYCINAMIDE RIBONUCLEOTIDE SYNTHESIS IN NEOPLASTIC CELLS BY PURINES AND ANALOGS.
    Biochimica et biophysica acta, 1965, Mar-15, Volume: 95

    Topics: Adenine; Animals; Antimetabolites; Antineoplastic Agents; Azaserine; Carcinoma, Squamous Cell; Glycine; Hypoxanthines; Imidazoles; Leukemia L1210; Mercaptopurine; Nucleotides; Pharmacology; Purines; Research; Ribonucleotides; Thioguanine; Tissue Culture Techniques; Xanthines

1965
[Purinethol therapy leukoses of childhood].
    Arztliche Wochenschrift, 1955, Jan-07, Volume: 10, Issue:1

    Topics: Child; Humans; Infant; Leukemia; Mercaptopurine; Purines

1955
Microbiological effects of 6-mercaptopurine.
    Annals of the New York Academy of Sciences, 1954, Dec-06, Volume: 60, Issue:2

    Topics: Humans; Lactobacillus; Mercaptopurine; Purines

1954
Activities of 6-mercaptopurine and related compounds on embryonic and regenerating tissues of Rana pipiens.
    Annals of the New York Academy of Sciences, 1954, Dec-06, Volume: 60, Issue:2

    Topics: Animals; Mercaptopurine; Purines; Rana pipiens; Wound Healing

1954
Biological activities of 6-mercaptopurine: effects on Streptococcus faecalis.
    Annals of the New York Academy of Sciences, 1954, Dec-06, Volume: 60, Issue:2

    Topics: Enterococcus faecalis; Humans; Mercaptopurine; Purines; Streptococcus

1954
The effect of 6-mercaptopurine on the rat fetus and on reproduction of the rat.
    Annals of the New York Academy of Sciences, 1954, Dec-06, Volume: 60, Issue:2

    Topics: Animals; Fetus; Mercaptopurine; Purines; Rats; Reproduction

1954
Effects of 6-mercaptopurine on experimental tumors in tissue culture.
    Annals of the New York Academy of Sciences, 1954, Dec-06, Volume: 60, Issue:2

    Topics: Animals; Mercaptopurine; Neoplasms, Experimental; Purines; Sarcoma, Experimental; Tissue Culture Techniques

1954
Effects of 6-mercaptopurine and analogs on experimental tumors.
    Annals of the New York Academy of Sciences, 1954, Dec-06, Volume: 60, Issue:2

    Topics: Humans; Mercaptopurine; Neoplasms; Neoplasms, Experimental; Purines

1954
Response of acute lymphocytic leukemias to the purine antagonist 6-mercaptopurine.
    Annals of the New York Academy of Sciences, 1954, Dec-06, Volume: 60, Issue:2

    Topics: Acute Disease; Humans; Leukemia; Leukemia, Lymphoid; Mercaptopurine; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Purines

1954
Studies on the toxicity and antileukemic action of 6-mercaptopurine in mice.
    Annals of the New York Academy of Sciences, 1954, Dec-06, Volume: 60, Issue:2

    Topics: Animals; Leukemia, Experimental; Mercaptopurine; Mice; Purines

1954
Effects of 6-mercaptopurine on experimental tumors.
    Annals of the New York Academy of Sciences, 1954, Dec-06, Volume: 60, Issue:2

    Topics: Animals; Mercaptopurine; Neoplasms, Experimental; Purines

1954
The effects of 6-mercaptopurine, 8-azaguanine, and 1,4-dimethanesulfonyloxybutane on an experimental brain tumor: preliminary observations.
    Annals of the New York Academy of Sciences, 1954, Dec-06, Volume: 60, Issue:2

    Topics: Animals; Azaguanine; Brain; Brain Neoplasms; Glycols; Guanine; Mercaptopurine; Neoplasms, Experimental; Purines

1954
The toxic effects of 6-mercaptopurine and related compounds.
    Annals of the New York Academy of Sciences, 1954, Dec-06, Volume: 60, Issue:2

    Topics: Humans; Mercaptopurine; Purines

1954
On the mechanism of action of 6-mercaptopurine.
    Annals of the New York Academy of Sciences, 1954, Dec-06, Volume: 60, Issue:2

    Topics: Humans; Mercaptopurine; Purines

1954
Clinical studies on 6-mercaptopurine.
    Annals of the New York Academy of Sciences, 1954, Dec-06, Volume: 60, Issue:2

    Topics: Mercaptopurine; Neoplasms; Purines

1954
Statistical analysis of clinical results from 6-mercaptopurine.
    Annals of the New York Academy of Sciences, 1954, Dec-06, Volume: 60, Issue:2

    Topics: Leukemia; Mercaptopurine; Purines

1954
Clinical experience with 6-mercaptopurine in human neoplasia.
    Annals of the New York Academy of Sciences, 1954, Dec-06, Volume: 60, Issue:2

    Topics: Leukemia; Mercaptopurine; Neoplasms; Purines

1954
A study of 61 leukemias treated with 6-mercaptopurine.
    Annals of the New York Academy of Sciences, 1954, Dec-06, Volume: 60, Issue:2

    Topics: Leukemia; Mercaptopurine; Purines

1954
The treatment of blastic leukemias with 6-mercaptopurine.
    Annals of the New York Academy of Sciences, 1954, Dec-06, Volume: 60, Issue:2

    Topics: Acute Disease; Leukemia; Mercaptopurine; Purines

1954
One-year evaluation of 6-mercaptopurine in the treatment of leukemia.
    Annals of the New York Academy of Sciences, 1954, Dec-06, Volume: 60, Issue:2

    Topics: Leukemia; Mercaptopurine; Purines

1954
Summary of experience with 6-mercaptopurine.
    Annals of the New York Academy of Sciences, 1954, Dec-06, Volume: 60, Issue:2

    Topics: Mercaptopurine; Neoplasms; Purines

1954
Leukemia in children: treatment of 22 cases with 6-mercaptopurine.
    Annals of the New York Academy of Sciences, 1954, Dec-06, Volume: 60, Issue:2

    Topics: Child; Humans; Infant; Leukemia; Mercaptopurine; Purines

1954
6-Mercaptopurine therapy in neoplastic disease.
    Annals of the New York Academy of Sciences, 1954, Dec-06, Volume: 60, Issue:2

    Topics: Mercaptopurine; Neoplasms; Purines

1954
The therapeutic effect of mercaptopurine in a variety of human neoplastic diseases.
    Annals of the New York Academy of Sciences, 1954, Dec-06, Volume: 60, Issue:2

    Topics: Mercaptopurine; Neoplasms; Purines

1954
Treatment of leukemia and related disorders with 6-mercaptopurine.
    Annals of the New York Academy of Sciences, 1954, Dec-06, Volume: 60, Issue:2

    Topics: Leukemia; Mercaptopurine; Neoplasms; Purines

1954
Clinical observations of the treatment of leukemia and allied disorders with 6-mercaptopurine.
    Annals of the New York Academy of Sciences, 1954, Dec-06, Volume: 60, Issue:2

    Topics: Arylsulfonates; Leukemia; Mercaptopurine; Neoplasms; Purines

1954
The use of 6-mercaptopurine in acute leukemia.
    Annals of the New York Academy of Sciences, 1954, Dec-06, Volume: 60, Issue:2

    Topics: Acute Disease; Leukemia; Mercaptopurine; Purines

1954
Role of mercaptopurine in the treatment of leukemia and related diseases.
    Annals of the New York Academy of Sciences, 1954, Dec-06, Volume: 60, Issue:2

    Topics: Leukemia; Mercaptopurine; Neoplasms; Purines

1954
Report on 6-mercaptopurine.
    Annals of the New York Academy of Sciences, 1954, Dec-06, Volume: 60, Issue:2

    Topics: Leukemia; Mercaptopurine; Purines

1954
Results obtained in the treatment of acute leukemia and lymphosarcoma with 6-mercaptopurine.
    Annals of the New York Academy of Sciences, 1954, Dec-06, Volume: 60, Issue:2

    Topics: Humans; Leukemia; Lymphoma; Lymphoma, Non-Hodgkin; Mercaptopurine; Purines

1954
6-Mercaptopurine therapy in leukemia.
    Annals of the New York Academy of Sciences, 1954, Dec-06, Volume: 60, Issue:2

    Topics: Leukemia; Mercaptopurine; Purines

1954
6-Mercaptopurine in acute leukemia.
    Annals of the New York Academy of Sciences, 1954, Dec-06, Volume: 60, Issue:2

    Topics: Acute Disease; Leukemia; Mercaptopurine; Purines

1954
Clinical experience using 6-mercaptopurine in childhood leukemia.
    Annals of the New York Academy of Sciences, 1954, Dec-06, Volume: 60, Issue:2

    Topics: Child; Humans; Infant; Leukemia; Mercaptopurine; Purines

1954
Clinical evaluation of 6-mercaptopurine.
    Annals of the New York Academy of Sciences, 1954, Dec-06, Volume: 60, Issue:2

    Topics: Leukemia; Mercaptopurine; Purines

1954
A clinical study of 6-mercaptopurine.
    Annals of the New York Academy of Sciences, 1954, Dec-06, Volume: 60, Issue:2

    Topics: Biomedical Research; Leukemia; Mercaptopurine; Neoplasms; Purines

1954
The treatment of leukemia with 6-mercaptopurine.
    Annals of the New York Academy of Sciences, 1954, Dec-06, Volume: 60, Issue:2

    Topics: Leukemia; Mercaptopurine; Purines

1954
The effect of 6-mercaptopurine in acute leukemia of children and adults: a preliminary report.
    Annals of the New York Academy of Sciences, 1954, Dec-06, Volume: 60, Issue:2

    Topics: Acute Disease; Leukemia; Mercaptopurine; Purines

1954
The clinical and hematological response of previously treated leukemic subjects to the antimetabolite 6-mercaptopurine.
    Annals of the New York Academy of Sciences, 1954, Dec-06, Volume: 60, Issue:2

    Topics: Antimetabolites; Leukemia; Mercaptopurine; Purines

1954
[Teratogenic effect of 6-mercaptopurine].
    Minerva pediatrica, 1955, Jan-27, Volume: 7, Issue:3-4

    Topics: Abnormalities, Severe Teratoid; Mercaptopurine; Purines

1955
MERCAPTOPURINE in leukemia.
    Nutrition reviews, 1955, Volume: 13, Issue:4

    Topics: Humans; Leukemia; Mercaptopurine; Purines

1955
Treatment of leukaemia and allied disorders with 6-mercaptopurine.
    British medical journal, 1955, May-07, Volume: 1, Issue:4922

    Topics: Arylsulfonates; Leukemia; Mercaptopurine; Purines

1955
[6-Mercaptopurine in therapy of leukemia].
    La Presse medicale, 1955, Mar-05, Volume: 63, Issue:17

    Topics: Leukemia; Mercaptopurine; Purines

1955
Antagonistic effects of 6-mercaptopurine and coenzyme A on mitochondria and mitosis in tissue culture.
    The Journal of biophysical and biochemical cytology, 1955, Volume: 1, Issue:2

    Topics: Animals; Antimetabolites; Cell Division; Coenzyme A; Coenzymes; Cytoplasm; Fibroblasts; Mercaptopurine; Mice; Mitochondria; Mitosis; Purines; Sarcoma 180; Tissue Culture Techniques

1955
[Early impressions of a case of acute infantile leukemia during 6-mercaptopurine therapy].
    Minerva pediatrica, 1955, Mar-31, Volume: 7, Issue:13

    Topics: Acute Disease; Child; Humans; Infant; Leukemia; Mercaptopurine; Purines

1955
Enzyme studies with mutant mammalian cells.
    The Journal of biological chemistry, 1960, Volume: 235

    Topics: Animals; Enzymes; Humans; Mercaptopurine; Purines; Research; Tissue Culture Techniques

1960
Comparative study of inhibitory action of ethionine, 8-azaguanine, 6-mercaptopurine and x- or gamma-irradiation on the induction of the hepatic drug-metabolizing enzymes by phenobarbital or phenaglycodol.
    Japanese journal of pharmacology, 1961, Volume: 11

    Topics: Antimetabolites; Azaguanine; Butylene Glycols; Enzymes; Ethionine; Meprobamate; Mercaptopurine; Pentobarbital; Phenobarbital; Purines; Radiation Effects; Tranquilizing Agents

1961
The effects of a series of 9-alkylpurines on the growth of sensitive and 6-MP-resistant H. Ep. 2 cells.
    Cancer research, 1962, Volume: 22

    Topics: Carcinoma; Carcinoma, Squamous Cell; Humans; Mercaptopurine; Purines

1962
The effect of 6-mercaptopurine riboside in 20 cases of childhood leukemia previously treated with purine antimetabolites.
    Cancer chemotherapy reports, 1961, Volume: 14

    Topics: Antimetabolites; Child; Humans; Infant; Leukemia; Mercaptopurine; Purines; Thioinosine

1961
DNA incorporation of 6-thioguanine nucleotides during maintenance therapy of childhood acute lymphoblastic leukaemia and non-Hodgkin lymphoma.
    Cancer chemotherapy and pharmacology, 2010, Volume: 66, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytosol; DNA; Drug Monitoring; Erythrocytes; Female; Guanine Nucleotides; Humans; Infant; Lymphoma, Non-Hodgkin; Male; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Purines; Thionucleotides

2010
Increased sensitivity to thiopurines in methylthioadenosine phosphorylase-deleted cancers.
    Molecular cancer therapeutics, 2011, Volume: 10, Issue:3

    Topics: Antimetabolites, Antineoplastic; Cell Line, Tumor; Drug Resistance, Neoplasm; Gene Deletion; Humans; Immunoblotting; Mercaptopurine; Neoplasms; Purine-Nucleoside Phosphorylase; Purines; Thioguanine; Thioinosine; Thionucleotides

2011
Thiopurines during pregnancy in inflammatory bowel disease: is there a risk for the (unborn) child?
    Expert review of gastroenterology & hepatology, 2013, Volume: 7, Issue:8

    Topics: Anti-Inflammatory Agents; Azathioprine; Female; Fetus; Gastrointestinal Agents; Humans; Inflammatory Bowel Diseases; Mercaptopurine; Pregnancy; Pregnancy Complications; Purines; Remission Induction; Risk Assessment; Risk Factors; Treatment Outcome

2013
Negative feedback-defective PRPS1 mutants drive thiopurine resistance in relapsed childhood ALL.
    Nature medicine, 2015, Volume: 21, Issue:6

    Topics: Adolescent; Child; Child, Preschool; Exome; Feedback, Physiological; Female; High-Throughput Nucleotide Sequencing; Humans; Infant; Leukemia, B-Cell; Male; Mercaptopurine; Mutation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Purines; Recurrence; Ribose-Phosphate Pyrophosphokinase; Tetrahydrofolates

2015
Clonal evolution mechanisms in NT5C2 mutant-relapsed acute lymphoblastic leukaemia.
    Nature, 2018, 01-25, Volume: 553, Issue:7689

    Topics: 5'-Nucleotidase; Animals; Cell Proliferation; Clonal Evolution; Disease Models, Animal; Drug Resistance, Neoplasm; Female; Gain of Function Mutation; Guanosine; HEK293 Cells; Humans; IMP Dehydrogenase; Male; Mercaptopurine; Mice; Mutation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Purines; Receptor, Notch1; Recurrence; Xenograft Model Antitumor Assays

2018