pulmicort and nitroaspirin

Chronicles in Drug Discovery features special interest reports on advances in drug discovery and development. This month we focus on the progress of the ongoing search for safe and effective chemopreventive agents. Chemoprevention is a strategy to decrease the risk of developing cancer by using agents that prevent or abrogate carcinogenic processes. Bowman- Birk inhibitor concentrate, budesonide, NCX-4016 and statins are all undergoing investigation in the clinical setting as potential chemopreventive agents for head and neck, lung, colon and breast cancers, respectively.

Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Aspirin; Budesonide; Cell Transformation, Neoplastic; Chemoprevention; Clinical Trials as Topic; Drug Evaluation, Preclinical; Glucocorticoids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Neoplasms; Precancerous Conditions; Trypsin Inhibitor, Bowman-Birk Soybean; Trypsin Inhibitors