pulegone and triptolide

pulegone has been researched along with triptolide* in 1 studies

Other Studies

1 other study(ies) available for pulegone and triptolide

Article	Year
Chiral auxiliaries for asymmetric radical cyclization reactions: application to the enantioselective synthesis of (+)-triptocallol. Organic letters, 2001, Jan-11, Volume: 3, Issue:1 [figure: see text] A series of epimeric 8-aryl menthyl derivatives 5a-d and 6a-l, prepared from the same chiral source (R)-pulegone, were employed as chiral auxiliaries in the asymmetric radical cyclization reactions of beta-keto esters mediated by Mn(OAc)3. Chiral precursors 8c and 8d provided the cyclization products 10c and 10d, respectively, as single isomers (dr > 99:1), whereas the cyclization of precursor 9k gave 13k with good stereoselectivity (dr = 24:1). Diastereomer 13e was employed as the key intermediate in the enantioselective synthesis of (+)-triptocallol in 90% ee. Topics: Biological Factors; Catalysis; Cyclization; Cyclohexane Monoterpenes; Diterpenes; Epoxy Compounds; Menthol; Molecular Structure; Monoterpenes; Phenanthrenes; Plants; Stereoisomerism; Structure-Activity Relationship; Terpenes	2001

Article

Year

Chiral auxiliaries for asymmetric radical cyclization reactions: application to the enantioselective synthesis of (+)-triptocallol.

Organic letters, 2001, Jan-11, Volume: 3, Issue:1

[figure: see text] A series of epimeric 8-aryl menthyl derivatives 5a-d and 6a-l, prepared from the same chiral source (R)-pulegone, were employed as chiral auxiliaries in the asymmetric radical cyclization reactions of beta-keto esters mediated by Mn(OAc)3. Chiral precursors 8c and 8d provided the cyclization products 10c and 10d, respectively, as single isomers (dr > 99:1), whereas the cyclization of precursor 9k gave 13k with good stereoselectivity (dr = 24:1). Diastereomer 13e was employed as the key intermediate in the enantioselective synthesis of (+)-triptocallol in 90% ee.

Topics: Biological Factors; Catalysis; Cyclization; Cyclohexane Monoterpenes; Diterpenes; Epoxy Compounds; Menthol; Molecular Structure; Monoterpenes; Phenanthrenes; Plants; Stereoisomerism; Structure-Activity Relationship; Terpenes

2001