pteridines has been researched along with tg100-115 in 6 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 2 (33.33) | 29.6817 |
2010's | 4 (66.67) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Dneprovskaia, E; Doukas, J; Fine, RM; Hood, J; Kang, X; Lohse, D; Martin, M; Noronha, G; Palanki, MS; Soll, RM; Wrasidlo, W; Yee, S; Zhu, H | 1 |
Acevedo, LM; Cheresh, DA; Dellamary, L; Dneprovskaia, E; Doukas, J; Eide, L; Martin, M; Noronha, G; Racanelli-Layton, A; Soll, R; Stebbins, K; Wrasidlo, W | 1 |
Ang, W; Chang, Y; Liu, Y; Luo, Y; Pi, W; Tang, J; Wang, Z; Xiong, L; Yang, T; Yang, X; Ye, W | 1 |
Bouvet, M; Cappello, P; Foubert, P; Hardamon, CR; Hirsch, E; Kaneda, MM; Lowy, AM; Mose, E; Nguyen, AV; Novelli, F; Ralainirina, N; Sasik, R; Schmid, MC; Sun, P; Valasek, MA; Varner, JA | 1 |
Bae, Y; Hur, W; Jun, J; Kim, ND; Lee, H; Lee, KB; Park, JY; Sim, T; Song, C | 1 |
Li, G; Zhao, L | 1 |
6 other study(ies) available for pteridines and tg100-115
Article | Year |
---|---|
Discovery of 3,3'-(2,4-diaminopteridine-6,7-diyl)diphenol as an isozyme-selective inhibitor of PI3K for the treatment of ischemia reperfusion injury associated with myocardial infarction.
Topics: Animals; Antigens, CD; Cadherins; Capillary Permeability; Cell Proliferation; Cells, Cultured; Endothelial Cells; Humans; Isoenzymes; Male; Models, Molecular; Myocardial Infarction; Myocardial Reperfusion Injury; Phenols; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Pteridines; Pyrazines; Pyridines; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Umbilical Veins; Vascular Endothelial Growth Factor A | 2007 |
Aerosolized phosphoinositide 3-kinase gamma/delta inhibitor TG100-115 [3-[2,4-diamino-6-(3-hydroxyphenyl)pteridin-7-yl]phenol] as a therapeutic candidate for asthma and chronic obstructive pulmonary disease.
Topics: Administration, Intranasal; Aerosols; Animals; Anti-Inflammatory Agents; Asthma; Bronchial Hyperreactivity; Class Ib Phosphatidylinositol 3-Kinase; Disease Models, Animal; Isoenzymes; Lipopolysaccharides; Mice; Neutrophils; Phenols; Phosphatidylinositol 3-Kinases; Pteridines; Pulmonary Disease, Chronic Obstructive | 2009 |
Phosphoinositide 3-kinase δ/γ inhibition does not prevent concanavalin A-induced hepatitis.
Topics: Animals; Apoptosis; Cell Proliferation; Cells, Cultured; Chemical and Drug Induced Liver Injury; Class I Phosphatidylinositol 3-Kinases; Class Ib Phosphatidylinositol 3-Kinase; Concanavalin A; Cytokines; Female; Hepatitis; Hepatocytes; Humans; Immunoenzyme Techniques; Inflammation; Mice; Mice, Inbred BALB C; Mitogens; Phenols; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Pteridines | 2013 |
Macrophage PI3Kγ Drives Pancreatic Ductal Adenocarcinoma Progression.
Topics: Animals; Antineoplastic Agents; Biomarkers; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Movement; Class Ib Phosphatidylinositol 3-Kinase; Disease Models, Animal; Disease Progression; Gene Expression; Gene Knockout Techniques; Heterografts; Humans; Immunomodulation; Macrophage Activation; Macrophages; Male; Mice; Mice, Knockout; Mice, Transgenic; Mortality; Neoplasm Metastasis; Pancreatic Neoplasms; Phenols; Phosphoinositide-3 Kinase Inhibitors; Platelet-Derived Growth Factor; Pteridines; Xenograft Model Antitumor Assays | 2016 |
Identification of TG100-115 as a new and potent TRPM7 kinase inhibitor, which suppresses breast cancer cell migration and invasion.
Topics: Adenosine Triphosphate; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cyclic AMP Response Element-Binding Protein; Female; Focal Adhesion Protein-Tyrosine Kinases; Humans; Neoplasm Invasiveness; Nonmuscle Myosin Type IIA; Phenols; Phosphorylation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pteridines; TRPM Cation Channels | 2017 |
Sorafenib-loaded hydroxyethyl starch-TG100-115 micelles for the treatment of liver cancer based on synergistic treatment.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Drug Delivery Systems; Hydroxyethyl Starch Derivatives; Liver Neoplasms, Experimental; Mice, Nude; Micelles; Phenols; Polyethylene Glycols; Pteridines; Rats; Rats, Sprague-Dawley; Sorafenib; Tumor Microenvironment; Xenograft Model Antitumor Assays | 2019 |