Compounds > pteridines

pteridines and sd-208

pteridines has been researched along with sd-208 in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's10 (27.78)29.6817
2010's24 (66.67)24.3611
2020's2 (5.56)2.80

Authors

AuthorsStudies
Bonniaud, P; Chakravarty, S; Damm, D; Dugar, S; Gauldie, J; Higgins, L; Kapoun, AM; Kolb, M; Margetts, PJ; Murphy, A; Protter, AA; Schroeder, JA1
Chakravarty, S; Damm, D; Dugar, S; Gaspar, NJ; Higgins, LS; Kapoun, AM; Lam, A; Liu, X; Liu, YW; Ma, JY; Munson, K; Murphy, A; O'young, G; Protter, AA; Quon, D; Rennard, SI; Tran, TT; Wang, Y; Wen, FQ1
Akhurst, RJ1
Barnard, N; Chakravarty, J; Dugar, S; Ge, R; Lattime, E; Medicherla, S; Murphy, A; Protter, A; Rajeev, V; Ray, P; Reiss, M; Rittling, S; Schreiner, G1
Chung, KF; Leung, SY; Medicherla, S; Niimi, A; Noble, A; Oates, T; Protter, AA; Williams, AS1
Collins, A; Cui, X; Dodds, R; Farrell, F; Gechtman, Z; Higgins, L; Hughes, A; Jolliffe, L; Murphy, A; Xu, D1
Chakravarty, S; Damm, DL; Gaspar, NJ; Henson, M; Higgins, LS; Kapoun, AM; Li, G; Li, L; Medicherla, S; Muiru, GT; Murphy, A; O'Young, G; Quon, D; Reddy, M; Wong, DH1
Bhagat, TD; Bitzer, M; Boultwood, J; Braunchweig, I; Chubak, A; Das, B; Gundabolu, K; Hayman, J; Higgins, LS; Kambhampati, S; Kapoun, AM; List, AF; Medicherla, S; Mo, Y; Navas, TA; Nguyen, AN; Pahanish, P; Parmar, S; Pellagatti, A; Platanias, LC; Sohal, D; Verma, A; Wickrema, A; Ying Ma, J; Zhang, Y; Zhou, L1
Bridgman, PG; Cameron, VA; Ellmers, LJ; Medicherla, S; Pilbrow, AP; Protter, AA; Richards, AM; Scott, NJ; Yandle, TG1
Abraham, DJ; Carulli, MT; Denton, CP; Khan, K; Lindahl, G; Ong, VH; Xu, S1
Klaassen, I; Schlingemann, RO; Van Geest, RJ; Van Noorden, CJ; Vogels, IM1
Dunn, LK; Duong, V; Fournier, PG; Guise, TA; Javelaud, D; Mauviel, A; McKenna, CR; Mohammad, KS; Niewolna, M; Peng, XH1
Martin-Martin, N; McMorrow, T; Ryan, MP; Slattery, C1
Collette, NM; Genetos, DC; Keller, H; Leupin, O; Loots, GG; Murugesh, D1
Anderson, J; Cucinotta, FA; Hada, M; Huff, J; O'Neill, P; Pluth, JM; Wang, M1
Cohen, JR; Fernando, RI; Hamilton, DH; Huang, B; Larocca, C; Palena, C1
Abi-Char, J; Coenen, T; Driesen, RB; Fagard, RH; Lijnen, PJ; Nagaraju, CK; Petrov, VV; Sipido, KR1
Barnhart, M; Hartman, R; Lekic, T; Manaenko, A; Zhang, JH1
Cheng, C; Deng, P; Huang, X; Liu, Z; Ren, L; Sun, Y; Wang, K; Wu, C; Wu, J; Xia, J; Ye, P; Yue, Z; Zhang, A1
Abastabar, M; Akbari, A; Amanpour, S; Dehpour, AR; Faghihloo, E; Ghaffari, SH; Ghahremani, MH; Heidari, M; Karimi, A; Khoshzaban, A; Mobini, GR; Muhammadnejad, S; Shidfar, F1
Amadio, PC; An, KN; Gingery, A; Passe, SM; Yang, TH; Zhao, C1
Amiaud, J; Bougras, G; Chesneau, J; Heymann, D; Heymann, MF; Lamora, A; Le Deley, MC; Leduc, M; Redini, F; Stresing, V; Talbot, J; Taurelle, J; Verrecchia, F1
Chen, Y; Creighton, CJ; Dakhova, O; Dang, TD; Guo, D; Ittmann, MM; Rowley, DR; Shen, T; Yang, F; Zhang, Y1
Buijs, JT; Cheung, H; Cohen, R; Corver, WE; Guise, TA; Jonkers, J; Kruithof-de Julio, M; Matula, KM; Mohammad, KS; Snoeks, TJ; van der Mark, MH; van der Pluijm, G1
Carder, EJ; Deng, F; Farber, E; Salamoun, JM; Tandon, M; Tang, H; Wang, QJ; Wipf, P; Xu, S1
Chirgwin, JM; Clines, GA; Fournier, PG; Guise, TA; Jiang, G; Juárez, P; Kim, HS; Liu, Y; Mohammad, KS; Niewolna, M; Peng, XH; Walton, HW; Wells, CD1
Abed Khojasteh, H; Akbari, A; Bolhassani, M; Fadakar, P; Ghassemi, F; Heidari, M; Mobini, GR; Mohebi, M1
Fang, Y; Gu, C; Li, M; Mao, ZG; Ni, T; Yang, PG; Yao, M; Yu, WR1
Han, F; Jiang, M; Li, J; Liu, Y; Liu, Z; Luo, B; Shen, Z; Wang, J; Xu, K; Zhang, Z; Zhang, ZY1
Cordazzo, C; Dees, C; Distler, JH; Distler, O; Krasowska, D; Liang, R; Mallano, T; Michalska-Jakubus, M; Ramming, A; Schett, G; Šenolt, L; Šumová, B; Wohlfahrt, T; Zhang, Y1
Burghardt, I; Papa, E; Szabó, E; Ventura, E; Weiss, T; Weller, M1
Bormann, F; Germing, U; Geyh, S; Gutekunst, J; Haas, R; Jäger, P; Kobbe, G; Koch, A; Lyko, F; Rodríguez-Paredes, M; Schroeder, T; Zilkens, C1
Chantry, AD; Down, JM; Evans, HR; Green, AC; Hudson, K; Lath, D; Lawson, MA; Owen, R; Paton-Hough, J; Reilly, GC; Walkley, B1
Chompre, G; Cruz, M; Martinez-Orengo, N; Noel, RJ; Porter, JT1
Gao, N; He, Q; Ji, J; Li, Y; Liu, J; Ma, L; Wang, Q; Yang, R; Zhou, X1
Chen, H; Guo, SX; Li, XD; Li, XW; Wang, H; Zhang, S1

Reviews

1 review(s) available for pteridines and sd-208

ArticleYear
Large- and small-molecule inhibitors of transforming growth factor-beta signaling.
    Current opinion in investigational drugs (London, England : 2000), 2006, Volume: 7, Issue:6

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Clinical Trials as Topic; Humans; Neoplasms; Oligonucleotides, Antisense; Patient Selection; Pteridines; Receptors, Transforming Growth Factor beta; Signal Transduction; Transforming Growth Factor beta

2006

Other Studies

35 other study(ies) available for pteridines and sd-208

ArticleYear
Progressive transforming growth factor beta1-induced lung fibrosis is blocked by an orally active ALK5 kinase inhibitor.
    American journal of respiratory and critical care medicine, 2005, Apr-15, Volume: 171, Issue:8

    Topics: Activin Receptors, Type I; Administration, Oral; Animals; Cells, Cultured; Down-Regulation; Female; Fibroblasts; Lung; Oligonucleotide Array Sequence Analysis; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pteridines; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Transforming Growth Factor beta; Transforming Growth Factor beta1; Up-Regulation

2005
Transforming growth factor-beta receptor type 1 (TGFbetaRI) kinase activity but not p38 activation is required for TGFbetaRI-induced myofibroblast differentiation and profibrotic gene expression.
    Molecular pharmacology, 2006, Volume: 70, Issue:2

    Topics: Activin Receptors, Type I; Cell Differentiation; Cells, Cultured; Collagen; Connective Tissue Growth Factor; Cytoskeleton; Fibroblasts; Gene Expression Regulation; Humans; Immediate-Early Proteins; Inflammation; Intercellular Signaling Peptides and Proteins; Lung; MAP Kinase Signaling System; Oligonucleotide Array Sequence Analysis; p38 Mitogen-Activated Protein Kinases; Protein Serine-Threonine Kinases; Pteridines; Pulmonary Fibrosis; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Smad Proteins; Transforming Growth Factor beta; Wound Healing

2006
Inhibition of growth and metastasis of mouse mammary carcinoma by selective inhibitor of transforming growth factor-beta type I receptor kinase in vivo.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Jul-15, Volume: 12, Issue:14 Pt 1

    Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinoma; Cell Proliferation; Disease Progression; Epithelium; Gene Expression Regulation, Neoplastic; Humans; Inhibitory Concentration 50; Mammary Neoplasms, Animal; Mesoderm; Mice; Mice, Nude; Neoplasm Metastasis; Plasminogen Activator Inhibitor 1; Protein Serine-Threonine Kinases; Pteridines; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta

2006
Effect of transforming growth factor-beta receptor I kinase inhibitor 2,4-disubstituted pteridine (SD-208) in chronic allergic airway inflammation and remodeling.
    The Journal of pharmacology and experimental therapeutics, 2006, Volume: 319, Issue:2

    Topics: Acetylcholine; Activin Receptors, Type I; Animals; Asthma; Bromodeoxyuridine; Bronchi; Chronic Disease; Dose-Response Relationship, Drug; Female; Immunoglobulin E; Muscle, Smooth; Ovalbumin; Protein Serine-Threonine Kinases; Pteridines; Rats; Rats, Inbred BN; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Smad2 Protein; Smad3 Protein; Transforming Growth Factor beta

2006
Potential involvement of BMP receptor type IB activation in a synergistic effect of chondrogenic promotion between rhTGFbeta3 and rhGDF5 or rhBMP7 in human mesenchymal stem cells.
    Growth factors (Chur, Switzerland), 2006, Volume: 24, Issue:4

    Topics: Activin Receptors, Type I; Bone Morphogenetic Protein 7; Bone Morphogenetic Protein Receptors, Type I; Bone Morphogenetic Proteins; Chondrogenesis; Drug Synergism; Growth Differentiation Factor 5; Humans; Mesenchymal Stem Cells; Phosphorylation; Pteridines; Smad Proteins; Transforming Growth Factor beta1; Transforming Growth Factor beta3; Up-Regulation

2006
Inhibition of transforming growth factor beta signaling reduces pancreatic adenocarcinoma growth and invasiveness.
    Molecular pharmacology, 2007, Volume: 72, Issue:1

    Topics: Activin Receptors, Type I; Adenocarcinoma; Animals; Cell Line, Tumor; Cell Proliferation; Genes, myc; Humans; Male; Mice; Mice, Nude; Neoplasm Invasiveness; Neoplasm Transplantation; Pancreatic Neoplasms; Protein Serine-Threonine Kinases; Pteridines; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Signal Transduction; Smad2 Protein; Transforming Growth Factor beta; Transplantation, Heterologous; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor C

2007
Inhibition of the TGF-beta receptor I kinase promotes hematopoiesis in MDS.
    Blood, 2008, Oct-15, Volume: 112, Issue:8

    Topics: Aged; Aged, 80 and over; Animals; Antigens, CD34; Bone Marrow; Female; Hematopoiesis; Humans; Lentivirus; Male; Mice; Mice, Transgenic; Middle Aged; Models, Biological; Myelodysplastic Syndromes; Protein Serine-Threonine Kinases; Pteridines; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta

2008
Transforming growth factor-beta blockade down-regulates the renin-angiotensin system and modifies cardiac remodeling after myocardial infarction.
    Endocrinology, 2008, Volume: 149, Issue:11

    Topics: Animals; Cardiomegaly; Down-Regulation; Drug Evaluation, Preclinical; Gene Expression Regulation; Heart; Kidney; Male; Mice; Mice, Inbred C57BL; Myocardial Infarction; Myocardium; Pteridines; Receptors, Transforming Growth Factor beta; Renin; Renin-Angiotensin System; Transforming Growth Factor beta; Ventricular Remodeling

2008
Cross-talk between MCP-3 and TGFbeta promotes fibroblast collagen biosynthesis.
    Experimental cell research, 2009, Jan-15, Volume: 315, Issue:2

    Topics: Animals; Cells, Cultured; Chemokine CCL7; Collagen; Collagen Type I; Enzyme Inhibitors; Fibroblasts; Gene Expression; Mice; Oligonucleotide Array Sequence Analysis; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Pteridines; Recombinant Proteins; RNA, Small Interfering; Signal Transduction; Smad3 Protein; Transforming Growth Factor beta

2009
Differential TGF-{beta} signaling in retinal vascular cells: a role in diabetic retinopathy?
    Investigative ophthalmology & visual science, 2010, Volume: 51, Issue:4

    Topics: Animals; Blotting, Western; Cattle; Cells, Cultured; Diabetic Retinopathy; Endothelium, Vascular; Fibronectins; Pericytes; Phosphorylation; Plasminogen Activator Inhibitor 1; Protein Serine-Threonine Kinases; Pteridines; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Retinal Vessels; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Smad2 Protein; Smad7 Protein; Transforming Growth Factor beta

2010
TGF-beta-RI kinase inhibitor SD-208 reduces the development and progression of melanoma bone metastases.
    Cancer research, 2011, Jan-01, Volume: 71, Issue:1

    Topics: Animals; Base Sequence; Bone Neoplasms; Cell Line, Tumor; Disease Models, Animal; Disease Progression; DNA Primers; Gene Expression Profiling; Humans; Melanoma; Mice; Mice, Nude; Neoplasm Invasiveness; Phosphorylation; Protein Kinase Inhibitors; Pteridines; Receptors, Transforming Growth Factor beta; Smad Proteins

2011
TGF-β1 mediates sirolimus and cyclosporine A-induced alteration of barrier function in renal epithelial cells via a noncanonical ERK1/2 signaling pathway.
    American journal of physiology. Renal physiology, 2011, Volume: 301, Issue:6

    Topics: Animals; Butadienes; Cell Line; Claudin-1; Cyclosporine; Electric Impedance; Enzyme Inhibitors; Epithelial Cells; Gene Expression; Immunosuppressive Agents; Kidney; MAP Kinase Signaling System; Membrane Proteins; Nitriles; Pteridines; Sirolimus; Smad Proteins; Swine; Transforming Growth Factor beta1; Up-Regulation

2011
TGF-β regulates sclerostin expression via the ECR5 enhancer.
    Bone, 2012, Volume: 50, Issue:3

    Topics: Activins; Animals; Bone Morphogenetic Proteins; Cell Line; Enhancer Elements, Genetic; Genetic Markers; Male; Mice; Osteoblasts; Parathyroid Hormone; Pteridines; Rats; Signal Transduction; Transforming Growth Factor beta

2012
Heavy ions can enhance TGFβ mediated epithelial to mesenchymal transition.
    Journal of radiation research, 2012, Volume: 53, Issue:1

    Topics: Animals; beta Catenin; Cell Line, Transformed; Dose-Response Relationship, Radiation; Epithelial Cells; Epithelial-Mesenchymal Transition; Esophagus; Extracellular Matrix Proteins; Heavy Ions; Humans; Iron; Lung; Mink; Phosphorylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Pteridines; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Recombinant Proteins; Silicon; Smad2 Protein; Smad7 Protein; Transforming Growth Factor beta1

2012
An autocrine loop between TGF-β1 and the transcription factor brachyury controls the transition of human carcinoma cells into a mesenchymal phenotype.
    Molecular cancer therapeutics, 2013, Volume: 12, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cisplatin; Drug Evaluation, Preclinical; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Feedback, Physiological; Fetal Proteins; Gene Expression Regulation, Neoplastic; Humans; Neoplasms; Phenotype; Pteridines; Receptors, Transforming Growth Factor beta; Signal Transduction; T-Box Domain Proteins; Transforming Growth Factor beta1; Vinblastine; Vinorelbine

2013
Reversible and irreversible differentiation of cardiac fibroblasts.
    Cardiovascular research, 2014, Mar-01, Volume: 101, Issue:3

    Topics: Animals; Cell Differentiation; Cells, Cultured; Collagen; Gene Expression; Male; Myofibroblasts; Pteridines; Rats; Rats, Wistar; Receptors, Transforming Growth Factor beta; Stress, Physiological; Transforming Growth Factor beta1

2014
Inhibition of transforming growth factor-β attenuates brain injury and neurological deficits in a rat model of germinal matrix hemorrhage.
    Stroke, 2014, Volume: 45, Issue:3

    Topics: Adult; Animals; Atrophy; Blotting, Western; Brain Injuries; Cerebral Ventricles; Extracellular Matrix Proteins; Female; Glial Fibrillary Acidic Protein; Humans; Hydrocephalus; Immunohistochemistry; Intracranial Hemorrhages; Nervous System Diseases; Neurologic Examination; Pregnancy; Pteridines; Rats; Rats, Sprague-Dawley; Signal Transduction; Survival; Transforming Growth Factor beta; Vitronectin; Weight Loss

2014
Inhibition of intimal hyperplasia in murine aortic allografts by the oral administration of the transforming growth factor-beta receptor I kinase inhibitor SD-208.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2014, Volume: 33, Issue:6

    Topics: Administration, Oral; Allografts; Animals; Aorta; Arteriosclerosis; Cell Movement; Cell Proliferation; Hyperplasia; Mice, Inbred BALB C; Mice, Inbred C57BL; Myocytes, Smooth Muscle; Neointima; Pteridines; Tunica Intima

2014
Evaluation of antitumor activity of a TGF-beta receptor I inhibitor (SD-208) on human colon adenocarcinoma.
    Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences, 2014, Jun-05, Volume: 22

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Female; Humans; Mice; Mice, Inbred C57BL; Neovascularization, Pathologic; Pteridines; Transforming Growth Factor beta; Xenograft Model Antitumor Assays

2014
TGF-β signaling regulates fibrotic expression and activity in carpal tunnel syndrome.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2014, Volume: 32, Issue:11

    Topics: Adult; Biopsy; Cadaver; Carpal Tunnel Syndrome; Collagen Type I; Collagen Type III; Connective Tissue Growth Factor; Fibroblasts; Fibrosis; Gene Expression Regulation; Humans; Middle Aged; Oligonucleotide Array Sequence Analysis; Pteridines; Signal Transduction; Smad3 Protein; Transforming Growth Factor beta

2014
Overexpression of smad7 blocks primary tumor growth and lung metastasis development in osteosarcoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2014, Oct-01, Volume: 20, Issue:19

    Topics: Animals; Bone Neoplasms; Bone Resorption; Cell Line, Tumor; Disease Models, Animal; Female; Gene Expression; Heterografts; Humans; Lung Neoplasms; Mice; Osteoclasts; Osteosarcoma; Pteridines; Signal Transduction; Smad3 Protein; Smad7 Protein; Transforming Growth Factor beta; Tumor Burden

2014
Stromal TGF-β signaling induces AR activation in prostate cancer.
    Oncotarget, 2014, Nov-15, Volume: 5, Issue:21

    Topics: Androgens; Apoptosis; Benzamides; Blotting, Western; Bone Morphogenetic Protein 6; Cell Proliferation; Humans; Interleukin-6; Kallikreins; Male; Microarray Analysis; Nitriles; Phenylthiohydantoin; Prostate; Prostate-Specific Antigen; Prostatic Neoplasms; Pteridines; Real-Time Polymerase Chain Reaction; Receptors, Androgen; Receptors, Transforming Growth Factor beta; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serine Endopeptidases; Signal Transduction; Stromal Cells; Transforming Growth Factor beta; Tumor Cells, Cultured

2014
Spontaneous bone metastases in a preclinical orthotopic model of invasive lobular carcinoma; the effect of pharmacological targeting TGFβ receptor I kinase.
    The Journal of pathology, 2015, Volume: 235, Issue:5

    Topics: Animals; Apoptosis; Bone Neoplasms; Breast Neoplasms; Carcinoma, Lobular; Cdh1 Proteins; Cell Line, Tumor; Cell Proliferation; Female; Mammary Neoplasms, Experimental; Mice, Knockout; Neoplasm Micrometastasis; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pteridines; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Signal Transduction; Time Factors; Transfection; Tumor Burden; Tumor Suppressor Protein p53

2015
SD-208, a novel protein kinase D inhibitor, blocks prostate cancer cell proliferation and tumor growth in vivo by inducing G2/M cell cycle arrest.
    PloS one, 2015, Volume: 10, Issue:3

    Topics: Animals; Cell Proliferation; G2 Phase Cell Cycle Checkpoints; Humans; M Phase Cell Cycle Checkpoints; Male; Mice; Mice, Nude; Neoplasm Proteins; Neoplasms, Experimental; Prostatic Neoplasms; Protein Kinase C; Pteridines; Xenograft Model Antitumor Assays

2015
The TGF-β Signaling Regulator PMEPA1 Suppresses Prostate Cancer Metastases to Bone.
    Cancer cell, 2015, Jun-08, Volume: 27, Issue:6

    Topics: Animals; Bone Neoplasms; Cell Line, Tumor; Chlorocebus aethiops; COS Cells; Disease Models, Animal; Gene Knockdown Techniques; Hep G2 Cells; Humans; Male; Membrane Proteins; Mice; Mice, Nude; Prostatic Neoplasms; Pteridines; Signal Transduction; Transforming Growth Factor beta

2015
Evaluation of SD-208, a TGF-β-RI Kinase Inhibitor, as an Anticancer Agent in Retinoblastoma.
    Acta medica Iranica, 2016, Volume: 54, Issue:6

    Topics: Cell Line, Tumor; Cell Proliferation; Child; Gene Expression Regulation, Neoplastic; Humans; MicroRNAs; Pteridines; Real-Time Polymerase Chain Reaction; Retinal Neoplasms; Retinoblastoma; RNA, Neoplasm; Transforming Growth Factor beta

2016
[Effects of transforming growth factor β1 receptor inhibitor SD-208 on human hypertrophic scar].
    Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns, 2016, Jul-20, Volume: 32, Issue:7

    Topics: Animals; Cell Movement; Cicatrix, Hypertrophic; Fibroblasts; Humans; Mice, Nude; Phalloidine; Pteridines; Rats; Rhodamines; Transforming Growth Factor beta1

2016
Resolvin D1 Programs Inflammation Resolution by Increasing TGF-β Expression Induced by Dying Cell Clearance in Experimental Autoimmune Neuritis.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2016, 09-14, Volume: 36, Issue:37

    Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Cells, Cultured; Disease Models, Animal; Docosahexaenoic Acids; Ectodysplasins; Enzyme Inhibitors; Forkhead Transcription Factors; Gene Expression Regulation; Macrophages; Male; Neuritis, Autoimmune, Experimental; Phagocytosis; Pteridines; Rats; Rats, Inbred Lew; Receptors, Lipoxin; Sciatic Nerve; T-Lymphocytes, Regulatory; Transforming Growth Factor beta

2016
The transcription factor GLI2 as a downstream mediator of transforming growth factor-β-induced fibroblast activation in SSc.
    Annals of the rheumatic diseases, 2017, Volume: 76, Issue:4

    Topics: Adult; Aged; Anilides; Animals; Cells, Cultured; Collagen Type I; Connective Tissue Growth Factor; Female; Fibroblasts; Fibrosis; Gene Knockout Techniques; Hedgehog Proteins; Humans; Kruppel-Like Transcription Factors; Male; Mice; Mice, Knockout; Mice, Transgenic; Middle Aged; Plasminogen Activator Inhibitor 1; Protein Serine-Threonine Kinases; Pteridines; Pulmonary Fibrosis; Pyridines; Pyrimidines; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Recombinant Proteins; RNA, Messenger; Scleroderma, Systemic; Signal Transduction; Skin; Smad3 Protein; Smoothened Receptor; Transforming Growth Factor beta; Young Adult; Zinc Finger Protein Gli2

2017
Negative control of the HGF/c-MET pathway by TGF-β: a new look at the regulation of stemness in glioblastoma.
    Cell death & disease, 2017, 12-13, Volume: 8, Issue:12

    Topics: Antineoplastic Agents; Butadienes; Cell Line, Tumor; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Glioblastoma; Hepatocyte Growth Factor; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neoplastic Stem Cells; Nitriles; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-met; Pteridines; Pyrazoles; Pyridazines; Pyrimidines; Pyrroles; Quinolines; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Signal Transduction; Transforming Growth Factor beta

2017
Transforming growth factor β1-mediated functional inhibition of mesenchymal stromal cells in myelodysplastic syndromes and acute myeloid leukemia.
    Haematologica, 2018, Volume: 103, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Bone Marrow; Bone Marrow Cells; Cell Differentiation; Female; Gene Expression Profiling; Gene Expression Regulation; Hematopoiesis; Humans; Immunophenotyping; Leukemia, Myeloid, Acute; Male; Mesenchymal Stem Cells; Middle Aged; Myelodysplastic Syndromes; Osteogenesis; Phenotype; Pteridines; Sequence Analysis, RNA; Signal Transduction; Transforming Growth Factor beta1

2018
TGFβ Inhibition Stimulates Collagen Maturation to Enhance Bone Repair and Fracture Resistance in a Murine Myeloma Model.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2019, Volume: 34, Issue:12

    Topics: Alkaline Phosphatase; Animals; Bone Remodeling; Bortezomib; Cancellous Bone; Collagen; Disease Models, Animal; Female; Fractures, Bone; Green Fluorescent Proteins; Humans; Lenalidomide; Mesenchymal Stem Cells; Mice; Mice, SCID; Multiple Myeloma; Organ Size; Osteoblasts; Osteoclasts; Parathyroid Hormone-Related Protein; Pteridines; Transforming Growth Factor beta; Vascular Endothelial Growth Factor A; Wound Healing; X-Ray Microtomography

2019
TGFβRI antagonist inhibits HIV-1 Nef-induced CC chemokine family ligand 2 (CCL2) in the brain and prevents spatial learning impairment.
    Journal of neuroinflammation, 2019, Dec-11, Volume: 16, Issue:1

    Topics: Animals; Astrocytes; Brain; Cells, Cultured; Chemokine CCL2; Coculture Techniques; Male; nef Gene Products, Human Immunodeficiency Virus; Pteridines; Rats; Rats, Sprague-Dawley; Receptor, Transforming Growth Factor-beta Type I; Spatial Learning

2019
Dihydroartemisinin inhibits the tumorigenesis and metastasis of breast cancer via downregulating CIZ1 expression associated with TGF-β1 signaling.
    Life sciences, 2020, May-01, Volume: 248

    Topics: Animals; Antineoplastic Agents, Phytogenic; Artemisinins; Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Synergism; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Humans; Lymphatic Metastasis; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Nuclear Proteins; Pteridines; Signal Transduction; Smad Proteins; Snail Family Transcription Factors; Transforming Growth Factor beta1; Tumor Burden; Xenograft Model Antitumor Assays

2020
MiRNA-620 promotes TGF-β1-induced proliferation of airway smooth muscle cell through controlling PTEN/AKT signaling pathway.
    The Kaohsiung journal of medical sciences, 2020, Volume: 36, Issue:11

    Topics: Antagomirs; Apoptosis; Base Pairing; Base Sequence; Bronchi; Cell Proliferation; Gene Expression Regulation; Humans; MicroRNAs; Myocytes, Smooth Muscle; Oligoribonucleotides; Primary Cell Culture; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Pteridines; Signal Transduction; Transforming Growth Factor beta1

2020