pteridines and phenylalanine

pteridines has been researched along with phenylalanine in 113 studies

Research

Studies (113)

Timeframe	Studies, this research(%)	All Research%
pre-1990	102 (90.27)	18.7374
1990's	5 (4.42)	18.2507
2000's	3 (2.65)	29.6817
2010's	2 (1.77)	24.3611
2020's	1 (0.88)	2.80

Authors

Authors	Studies
Cotton, RG; Danks, DM; Schlesinger, P	1
Bettoni, O; Bieri, J; Curtius, HC; Niederwieser, A; Schaub, J; Schircks, B; Viscontini, M	1
Bartholomé, K; Clayton, BE; Curtius, H; Danks, DM; Gröbe, H; Kaufman, S; Leeming, R; Pfleiderer, W; Rembold, H; Rey, F	1
Cotton, RG; Danks, DM; Firgaira, F; Hennings, G; Rembold, H; Schlesinger, P; Watson, BM	1
Kokolis, N; Ziegler, I	1
Berlow, S; Kaufman, S; Milstien, S; Orloff, S; Pueschel, S; Schulman, JD; Spielberg, S; Summer, GK	1
Bartholomé, K; Bieri, JH; Curtius, HC; Däumling, S; Niederwieser, A; Schaub, J; Schircks, B; Viscontini, M	1
Blair, JA; Green, A; Leeming, RJ; Raine, DN	1
Zannoni, VG	1
Grimm, U; Knapp, A; Reddemann, H; Schlenzka, K	1
Blaskovics, M; Blau, N; Curtius, HC; Giudici, T; Kierat, L	1
Dhondt, JL	3
Bel, Y; Ferré, J	1
Duch, DS; Nichol, CA; Smith, GK	1
Cotton, RG	2
Esumi, N; Hibi, S; Imashuku, S; Kodo, N; Morioka, Y; Todo, S	1
Davis, MD; Kaufman, S; Parniak, MA	1
Howells, DW; Hyland, K; Smith, I	1
Applegarth, DA; Davidson, AG; Ennis, D; Naylor, EW; Niederwieser, A; Wong, LT	1
Boudha, A; Dhondt, JL; Farriaux, JP; Largillière, C; Leeming, RJ; Ringel, J; Roger, MM	1
Blonder, J; Cohen, BE; Normand, M; Peled, I; Quint, J; Szeinberg, A	1
Kaufman, S	8
Curtius, HC; Niederwieser, A; Ponzone, A	1
Hyland, K; Kendall, B; Smith, I	1
Güttler, F; Lou, HC; Lykkelund, C; Niederwieser, A; Rasmussen, V	1
Cavanagh, NP; Hyland, K; Leeming, RJ; Smith, I	1
Huang, CY; Kaufman, S	1
Fisher, DB; Kaufman, S	2
Abita, JP; Dorche, C; Kaufman, S	1
D'Iorio, A; Mavrides, C; Whitlow, KJ	1
Bagchi, SP; Zarycki, EP	1
Brase, DA; Westfall, TC	2
Dickens, G; Guroff, G; Letendre, CH	1
Ayling, JE; Helfand, GD	1
Jakubovic, A	1
Chan-Henry, E; Jakubovic, A; Woolf, LI	2
Hecker, E; Marks, F	1
Benoiton, NL; D'Iorio, A; Tong, JH	2
Frézal, J	1
Tourian, A; Treiman, DM	1
Mains, RE; Patterson, PH	1
al-Janabi, JM; Ayling, JE; Helfand, GD; Pirson, WD	1
Tourian, A	1
Bublitz, C	1
Kaufman, S; Storm, CB	1
Coulson, WF; Jepson, JB; Wardle, E	1
Guroff, G; Rhoads, CA	2
Jequier, E; Lovenberg, W; Robinson, DS; Sjoerdsma, A	1
Nielsen, KH	1
Guroff, G; Strenkoski, CA	1
Oakley, G; Strittmatter, CF	1
Broquist, HP; Fleming, AF	1
Scrimgeour, KG; Vonderschmitt, DJ	1
Britcher, SF; Kuehl, FA; Saari, WS; Williams, J; Wolf, DE	1
Grahame-Smith, DG	1
Leeming, RJ	1
Kapatos, G; Kaufman, S; Rizzo, WB; Schulman, JD; Tamarkin, L; Van Loon, GR	1
Iinuma, H; Koizumi, S; Matsushima, Y; Nagatsu, T; Takeuchi, T; Umezawa, H	1
Berlow, S; Hoganson, G; Kaufman, S; Matalon, R; Milstien, S; Naylor, E; Schuett, V; Seifert, W	1
Aziz, AA; Blair, JA; Leeming, RJ; Sylvester, PE	1
Curtius, HC; Niederwieser, A	1
Harpey, JP	1
Curtius, HC; Leeming, RJ; Niederwieser, A; Rey, F; Rey, J; Saudubray, JM	1
Beck, B; Brandt, NJ; Christensen, E; Niederwieser, A; Pedersen, PS	1
Akino, M; Arashima, S; Kawaguchi, M; Masada, M; Matsuo, N; Mizokami, T; Seki, T; Tsuchiya, T; Yoshida, T; Yoshioka, S	1
Lipson, A; O'Halloran, M; Potter, M; Wilken, B; Yu, J	1
Güttler, F; Lou, H; Lykkelund, C; Niederwieser, A	1
Døskeland, AP; Døskeland, SO; Flatmark, T; Ogreid, D	1
Smith, I	1
Dhondt, JL; Farriaux, JP; Largilliere, C; Leeming, RJ; Leroux, B	1
Barford, PA; Blair, JA; Leeming, RJ; Smith, I	1
Kaufman, S; Phillips, RS	1
Matalon, R	1
Atarés, M; Blau, N; Cardesa-Garcia, J; Joller, P; Niederwieser, A; Wang, M	1
Ardouin, P; Dautrevaux, M; Dhondt, JL; Farriaux, JP; Largilliere, C	2
Hase, Y; Iwai, K; Kobashi, M; Oura, T; Shintaku, H; Turuhara, T	1
Blair, JA; Leeming, RJ	1
Dhondt, JL; Farriaux, JP	1
Narisawa, K; Tada, K	1
Curtius, HC; Leupold, D; Niederwieser, A; Wang, M	1
Kapatos, G; Kaufman, S; McInnes, RR; Rizzo, WB; Schulman, JD	1
Ardouin, P; Dhondt, JL; Farriaux, JP; Hayte, JM	1
Cotton, RG; Danks, DM	1
Kaufman, S; Milstien, S; Summer, GK	1
Berlow, S	1
Blair, JA; Leeming, RJ; Rey, F; Rey, J	1
Bartholomé, K; Kaufman, S; Lee, CL; Milstien, S; Nixon, JC	1
Komada, S; Kuzuhara, S; Masuzugawa, S; Narita, Y; Taniguchi, A	1
Chen, D; Frey, PA	1
Belal, S; Dhondt, JL; Hentati, F; Kaabachi, N; Larnaout, A; Mebazza, A; Miladi, N	1
Boneh, A; Coyne, KE; Johnson, JL; Mackay, M; Pitt, J; Rajagopalan, KV; Van Hove, JL	1
Bahrami, S; Heller, R; Werner, ER; Werner-Felmayer, G	1
SCHWINCK, I	1
Bannink, M; Eggermont, AM; Fekkes, D; Kruit, WH; Mulder, PG; Stoter, G; Van Gool, AR; van Ojik, HH	1
Cody, V; Nowak, J; Pace, J	1
Chen, WH; Chen, WS; Chu, CM; Lee, CY; Liang, CY; Liu, MH; Wang, CH; Wang, MY; Wu, HP	1

Reviews

6 review(s) available for pteridines and phenylalanine

Article	Year
Biosynthesis and metabolism of tetrahydrobiopterin and molybdopterin. Annual review of biochemistry, 1985, Volume: 54 Topics: Alcohol Oxidoreductases; Animals; Biopterins; Body Fluids; Coenzymes; GTP Cyclohydrolase; Humans; Immune System Diseases; Mental Disorders; Metalloproteins; Molybdenum; Molybdenum Cofactors; Neoplasms; Nervous System Diseases; Phenylalanine; Phenylketonurias; Pteridines; Pterins; Tetrahydrofolate Dehydrogenase; Tissue Distribution; Tryptophan Hydroxylase; Tyrosine 3-Monooxygenase	1985
Pteridines and mono-amines: relevance to neurological damage. Postgraduate medical journal, 1986, Volume: 62, Issue:724 Topics: Amines; Biopterins; Folic Acid; Humans; Nervous System; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Pteridines	1986
The role of tetrahydrobiopterin in neurological disease: a review. Journal of mental deficiency research, 1981, Volume: 25 Pt 4 Topics: Aluminum; Biopterins; Brain; Dementia; Humans; Lead Poisoning; Nervous System Diseases; Neurotransmitter Agents; Phenylalanine; Phenylketonurias; Pteridines	1981
Tetrahydrobiopterin deficiencies: preliminary analysis from an international survey. The Journal of pediatrics, 1984, Volume: 104, Issue:4 Topics: Adjuvants, Pharmaceutic; Alcohol Oxidoreductases; Amino Acid Metabolism, Inborn Errors; Biopterins; Female; Folic Acid; GTP Cyclohydrolase; Humans; Infant; Infant, Newborn; Male; Neurotransmitter Agents; Phenylalanine; Phenylketonurias; Pteridines	1984
[Tetrahydroblopterin. Metabolism and metabolic role of unconjugated pteridines (author's transl)]. Pathologie-biologie, 1980, Volume: 28, Issue:6 Topics: Animals; Biological Transport; Biopterins; Cattle; Humans; Mice; Mixed Function Oxygenases; Neoplasms; Neurotic Disorders; Oxidation-Reduction; Phenylalanine; Phenylketonurias; Pteridines; Rats	1980
[Biogenic amines and hyperphenylalaninemia (author's transl)]. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 1981, Volume: 26, Issue:11 Topics: Biogenic Amines; Biopterins; Dihydropteridine Reductase; Humans; Infant; Mass Screening; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Pteridines	1981

Trials

1 trial(s) available for pteridines and phenylalanine

Article	Year
Pegylated interferon-alpha2b treatment in melanoma patients: influence on amino acids, 5-hydroxyindolacetic acid and pteridine plasma concentrations. Anti-cancer drugs, 2004, Volume: 15, Issue:6 Topics: Adult; Aged; Amino Acids; Biopterins; Drug Administration Schedule; Female; Humans; Hydroxyindoleacetic Acid; Injections, Subcutaneous; Interferon alpha-2; Interferon-alpha; Male; Melanoma; Middle Aged; Neopterin; Phenylalanine; Pilot Projects; Polyethylene Glycols; Pteridines; Randomized Controlled Trials as Topic; Recombinant Proteins; Time Factors; Tryptophan; Tyrosine	2004

Article

Year

Pegylated interferon-alpha2b treatment in melanoma patients: influence on amino acids, 5-hydroxyindolacetic acid and pteridine plasma concentrations.

Anti-cancer drugs, 2004, Volume: 15, Issue:6

Topics: Adult; Aged; Amino Acids; Biopterins; Drug Administration Schedule; Female; Humans; Hydroxyindoleacetic Acid; Injections, Subcutaneous; Interferon alpha-2; Interferon-alpha; Male; Melanoma; Middle Aged; Neopterin; Phenylalanine; Pilot Projects; Polyethylene Glycols; Pteridines; Randomized Controlled Trials as Topic; Recombinant Proteins; Time Factors; Tryptophan; Tyrosine

2004

Other Studies

106 other study(ies) available for pteridines and phenylalanine

Article	Year
Letter: Tetrahydrobiopterin treatment of variant form of phenylketonuria. Lancet (London, England), 1975, Nov-22, Volume: 2, Issue:7943 Topics: Administration, Oral; Biopterins; Female; Humans; Infant; Injections, Intravenous; Phenylalanine; Phenylketonurias; Pteridines	1975
Atypical phenylketonuria caused by 7, 8-dihydrobiopterin synthetase deficiency. Lancet (London, England), 1979, Jan-20, Volume: 1, Issue:8108 Topics: Alcohol Oxidoreductases; Biopterins; Child, Preschool; Female; Guanosine Triphosphate; Humans; Phenylalanine; Phenylketonurias; Pteridines; Pterins	1979
Malignant hyperphenylalaninaemia--current status (June 1977). Journal of inherited metabolic disease, 1978, Volume: 1, Issue:2 Topics: Amino Acid Metabolism, Inborn Errors; Female; Humans; Infant; Infant, Newborn; Male; Phenylalanine; Phenylketonurias; Pteridines	1978
Malignant hyperphenylalaninemia--clinical features, biochemical findings, and experience with administration of biopterins. Pediatric research, 1979, Volume: 13, Issue:10 Topics: Biopterins; Child, Preschool; Dihydropteridine Reductase; Female; Fibroblasts; Humans; Indoles; Infant; Infant, Newborn; Liver; Male; Phenylalanine; Pteridines	1979
On the levels of phenylalanine, tyrosine and tetrahydrobiopterin in the blood of tumor-bearing organisms. Cancer biochemistry biophysics, 1977, Volume: 2, Issue:2 Topics: Animals; Biopterins; Blood Proteins; Female; Humans; Hydroxylation; Male; Neoplasms; Neoplasms, Experimental; Phenylalanine; Protein Binding; Pteridines; Rats; Tyrosine	1977
Hyperphenylalaninemia due to a deficiency of biopterin. A variant form of phenylketonuria. The New England journal of medicine, 1978, Sep-28, Volume: 299, Issue:13 Topics: Administration, Oral; Biopterins; Child, Preschool; Dihydropteridine Reductase; Humans; Infant; Liver; Male; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Pteridines; Tetrahydrofolate Dehydrogenase	1978
Tetrahydrobiopterin therapy of atypical phenylketonuria due to defective dihydrobiopterin biosynthesis. Archives of disease in childhood, 1978, Volume: 53, Issue:8 Topics: Biopterins; Female; Humans; Infant; Phenylalanine; Phenylketonurias; Pteridines	1978
Protein deficiency in PKU. The New England journal of medicine, 1979, Jan-25, Volume: 300, Issue:4 Topics: Adult; Biopterins; Child; Humans; Liver; Phenylalanine; Phenylketonurias; Pteridines	1979
Biopterin derivatives in normal and phenylketonuric patients after oral loads of L-phenylalanine, L-tyrosine, and L-tryptophan. Archives of disease in childhood, 1976, Volume: 51, Issue:10 Topics: Administration, Oral; Adolescent; Adult; Biopterins; Child, Preschool; Chromatography, Thin Layer; Humans; Infant; Infant, Newborn; Phenylalanine; Phenylketonurias; Pteridines; Tryptophan; Tyrosine	1976
Liver phenylalanine hydroxylase assay. Biochemical medicine, 1976, Volume: 16, Issue:3 Topics: Animals; Colorimetry; Guinea Pigs; Humans; Liver; Methods; Mice; Phenylalanine; Phenylalanine Hydroxylase; Pteridines; Rats; Tyrosine	1976
[Phenylalanine hydroxylase activity in the liver as a parameter for distinguishing various forms of hyperphenylalaninemias (author's transl)]. Clinica chimica acta; international journal of clinical chemistry, 1975, Jan-06, Volume: 58, Issue:1 Topics: Adolescent; Adult; Amines; Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Female; Humans; Liver; Male; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Pteridines	1975
Hyperphenylalaninaemia presumably due to carbinolamine dehydratase deficiency: loading tests with pterin derivatives. Journal of inherited metabolic disease, 1992, Volume: 15, Issue:3 Topics: Biopterins; Female; Humans; Hydro-Lyases; Infant, Newborn; Kinetics; Phenylalanine; Pteridines; Pterins	1992
Strategy for the screening of tetrahydrobiopterin deficiency among hyperphenylalaninaemic patients: 15-years experience. Journal of inherited metabolic disease, 1991, Volume: 14, Issue:2 Topics: Belgium; Biopterins; Czechoslovakia; Diagnosis, Differential; Dihydropteridine Reductase; France; Humans; Infant, Newborn; Liver; Neonatal Screening; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Portugal; Prospective Studies; Pteridines; Retrospective Studies	1991
Regulation of pteridine biosynthesis and aromatic amino acid hydroxylation in Drosophila melanogaster. Biochemical genetics, 1989, Volume: 27, Issue:1-2 Topics: Amino Acids; Animals; Drosophila melanogaster; Hydroxylation; Mutation; Phenylalanine; Pteridines; Tryptophan; Tyrosine	1989
A model for hyperphenylalaninaemia due to tetrahydrobiopterin deficiency. Journal of inherited metabolic disease, 1986, Volume: 9, Issue:1 Topics: Animals; Biopterins; Brain; Catecholamines; Disease Models, Animal; Dose-Response Relationship, Drug; Hypoxanthines; Liver; Mice; Mice, Inbred BALB C; Phenylalanine; Pteridines	1986
Abnormal serum phenylalanine-tyrosine ratio and hyperferritinemia in malignant histiocytosis. Pediatric hematology and oncology, 1988, Volume: 5, Issue:4 Topics: Adolescent; Child; Child, Preschool; Female; Ferritins; Histiocytic Sarcoma; Humans; Infant; L-Lactate Dehydrogenase; Leukemia, Myeloid, Acute; Male; Measles; Phenylalanine; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pteridines; Tyrosine	1988
Effect of alkaline pH on the activity of rat liver phenylalanine hydroxylase. The Journal of biological chemistry, 1988, Jan-25, Volume: 263, Issue:3 Topics: Animals; Cold Temperature; Enzyme Activation; Hydrogen-Ion Concentration; Kinetics; Liver; NAD; Phenylalanine; Phenylalanine Hydroxylase; Pteridines; Rats; Spectrometry, Fluorescence	1988
Guanosine triphosphate cyclohydrolase I deficiency: early diagnosis by routine urine pteridine screening. Pediatrics, 1987, Volume: 79, Issue:3 Topics: Aminohydrolases; Biopterins; Chromatography, High Pressure Liquid; Diagnosis, Differential; GTP Cyclohydrolase; Humans; Infant, Newborn; Liver; Male; Neopterin; Phenylalanine; Phenylketonurias; Pteridines	1987
Neonatal hyperphenylalaninemia presumably caused by guanosine triphosphate-cyclohydrolase deficiency. The Journal of pediatrics, 1985, Volume: 106, Issue:6 Topics: Aminohydrolases; Biopterins; GTP Cyclohydrolase; Humans; Infant, Newborn; Leukocyte Count; Liver; Male; Neopterin; Phenylalanine; Pteridines; Pterins; T-Lymphocytes	1985
Malignant phenylketonuria due to defective synthesis of dihydrobiopterin. Israel journal of medical sciences, 1985, Volume: 21, Issue:6 Topics: 5-Hydroxytryptophan; Biopterins; Carbidopa; Drug Combinations; Female; Humans; Infant, Newborn; Levodopa; Male; Nervous System Diseases; Phenylalanine; Phenylketonurias; Pteridines; Tyrosine	1985
Hyperphenylalaninaemia caused by defects in biopterin metabolism. Journal of inherited metabolic disease, 1985, Volume: 8 Suppl 1 Topics: Amino Acid Metabolism, Inborn Errors; Animals; Biogenic Amines; Biopterins; Brain; Humans; Phenylalanine; Phenylketonurias; Pteridines	1985
Differential diagnosis of tetrahydrobiopterin deficiency. Journal of inherited metabolic disease, 1985, Volume: 8 Suppl 1 Topics: Amino Acid Metabolism, Inborn Errors; Biopterins; Diagnosis, Differential; GTP Cyclohydrolase; Humans; Phenylalanine; Phenylketonurias; Pteridines	1985
Clinical role of pteridine therapy in tetrahydrobiopterin deficiency. Journal of inherited metabolic disease, 1985, Volume: 8 Suppl 1 Topics: Amino Acid Metabolism, Inborn Errors; Biogenic Amines; Biopterins; Brain; Folic Acid; Folic Acid Deficiency; Humans; Infant; Phenylalanine; Phenylketonurias; Pteridines	1985
Biopterin, neopterin and tyrosine responses to combined oral phenylalanine and tetrahydrobiopterin loading tests in two normal children and in a girl with partial biopterin deficiency. Journal of inherited metabolic disease, 1985, Volume: 8 Suppl 2 Topics: Administration, Oral; Biopterins; Child; Female; Humans; Neopterin; Phenylalanine; Pteridines; Tyrosine	1985
Neurological aspects of biopterin metabolism. Archives of disease in childhood, 1986, Volume: 61, Issue:2 Topics: Adolescent; Biological Assay; Biopterins; Child; Child, Preschool; Dystonia Musculorum Deformans; Humans; Infant; Male; Nervous System Diseases; Phenylalanine; Phenylketonurias; Pteridines	1986
Studies on the mechanisms of action of phenylalanine hydroxylase and its protein stimulator. I. Enzyme concentration dependence of the specific activity of phenylalanine hydroxylase due to a nonenzymatic step. The Journal of biological chemistry, 1973, Jun-25, Volume: 248, Issue:12 Topics: Animals; Catalysis; Centrifugation, Density Gradient; Enzyme Activation; Hydroxylation; Kinetics; Liver; Mathematics; Models, Chemical; Molecular Weight; NADP; Oxygen; Phenylalanine; Phenylalanine Hydroxylase; Propylene Glycols; Protein Binding; Proteins; Pteridines; Quinones; Rats; Scattering, Radiation	1973
Tetrahydropterin oxidation without hydroxylation catalyzed by rat liver phenylalanine hydroxylase. The Journal of biological chemistry, 1973, Jun-25, Volume: 248, Issue:12 Topics: Animals; Azides; Carbon Isotopes; Catalase; Catalysis; Chymotrypsin; Free Radicals; Hydroxylation; Kinetics; Liver; Lysophosphatidylcholines; NADP; Oxidation-Reduction; Oxygen; Oxygen Consumption; Peroxidases; Phenylalanine; Phenylalanine Hydroxylase; Pteridines; Pyruvates; Rats; Sodium; Stereoisomerism; Tyrosine; Uncoupling Agents	1973
Futher studies on the nature of phenylalanine hydroxylation in brain. Pediatric research, 1974, Volume: 8, Issue:7 Topics: Animals; Animals, Newborn; Brain; Carbon Radioisotopes; Chromatography, Thin Layer; Female; Hydroxylation; Liver; Methods; Monoiodotyrosine; Phenylalanine; Phenylalanine Hydroxylase; Propylene Glycols; Pteridines; Rats; Tyrosine; Tyrosine 3-Monooxygenase	1974
The conversion of phenylalanine to tyrosine in Tetrahymena pyriformis. The Journal of protozoology, 1973, Volume: 20, Issue:2 Topics: Acetates; Animals; Carbon Isotopes; Cell-Free System; Chromatography, Paper; Culture Media; Glucose; Guanine Nucleotides; Phenylalanine; Phenylalanine Hydroxylase; Pteridines; Spectrophotometry; Stereoisomerism; Tetrahymena pyriformis; Tritium; Tyrosine	1973
Hydroxylation of phenylalanine by various areas of brain in vitro. Biochemical pharmacology, 1972, Feb-15, Volume: 21, Issue:4 Topics: Animals; Brain; Brain Stem; Carbon Isotopes; Catecholamines; Caudate Nucleus; Fenclonine; Hydroxylation; Hypothalamus; Lung; Methyltyrosines; Phenylalanine; Phenylalanine Hydroxylase; Pineal Gland; Pteridines; Rats; Spleen; Thalamus; Tyrosine	1972
Studies on the stimulation of phenylalanine hydroxylase activity by short-chain alcohols. Biochimica et biophysica acta, 1973, Jun-06, Volume: 309, Issue:2 Topics: 1-Propanol; Alcohols; Animals; Butanols; Cats; Enzyme Activation; Fenclonine; Fluorine; Guinea Pigs; Hydrogen-Ion Concentration; Kidney; Kinetics; Liver; Male; Methanol; Phenylalanine; Phenylalanine Hydroxylase; Pteridines; Rabbits; Rats; Species Specificity; Temperature	1973
The tryptophan hydroxylase of Chromobacterium violaceum. The Journal of biological chemistry, 1974, Nov-25, Volume: 249, Issue:22 Topics: 5-Hydroxytryptophan; Carbon Radioisotopes; Cell Division; Chromatography, DEAE-Cellulose; Chromatography, Paper; Chromobacterium; Enzyme Induction; Fenclonine; Hydrogen-Ion Concentration; Kinetics; Mixed Function Oxygenases; Oxidation-Reduction; Phenylalanine; Pteridines; Spectrometry, Fluorescence; Sulfhydryl Reagents; Time Factors; Tryptophan; Tryptophan Hydroxylase	1974
Inhibition of phenylalanine hydroxylase by p-chlorophenylalanine; dependence on cofactor structure. Biochemical and biophysical research communications, 1974, Nov-06, Volume: 61, Issue:1 Topics: Binding Sites; Catalase; Fenclonine; Hydrogen-Ion Concentration; Kinetics; Liver; Phenylalanine; Phenylalanine Hydroxylase; Propylene Glycols; Protein Binding; Pteridines; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Temperature; Tyrosine	1974
Phenylalanine-hydroxylating system in the human fetus at different developmental ages. Biochimica et biophysica acta, 1971, Jun-22, Volume: 237, Issue:3 Topics: Age Factors; Brain; Catalase; Dithiothreitol; Fetus; Humans; Kinetics; Liver; Mixed Function Oxygenases; NAD; Oxidoreductases; Phenylalanine; Phenylalanine Hydroxylase; Pteridines	1971
The inactivation of phenylalanine hydroxylase by 2-amino-4-hydroxy-6,7-dimethyltetrahydropteridine and the aerobic oxidation of the latter. The effects of catalase, dithiothreitol and reduced nicotinamide-adenine dinucleotide. The Biochemical journal, 1971, Volume: 125, Issue:2 Topics: Air; Animals; Catalase; Coenzymes; Dithiothreitol; Hydrogen Peroxide; Liver; Liver Extracts; Mice; Mixed Function Oxygenases; NAD; Oxidation-Reduction; Peroxides; Phenylalanine; Phenylalanine Hydroxylase; Pteridines; Rats; Tyrosine	1971
[On the metabolism and mechanism of action of estrogens. 8. The biogenesis and metabolism of 2-hydroxyestrone in relation to the formation of protein-bound and water soluble estrone metabolites and to NADPH oxidation in rat liver microsomes]. Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1966, Volume: 345, Issue:1 Topics: Aminopterin; Animals; Carbon Isotopes; Cysteine; Estrone; Female; Folic Acid; Glutathione; Humans; Kinetics; Liver; Male; Microsomes; NADP; Oxidation-Reduction; Phenylalanine; Phosphates; Protein Binding; Pteridines; Rats; Steroids	1966
The role of pteridine cofactors in mixed function oxidases. Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1968, Volume: 349, Issue:11 Topics: Adrenal Glands; Animals; Cattle; Liver; Mixed Function Oxygenases; NADP; Phenylalanine; Pteridines; Rats; Tyrosine	1968
The formation of 3,4-dihydroxy-L-phenylalanine from L-meta-tyrosine by rat liver and beef adrenal medulla. Biochemical and biophysical research communications, 1971, May-21, Volume: 43, Issue:4 Topics: Adrenal Glands; Amino Acids; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Autoanalysis; Cattle; Chemical Precipitation; Chromatography, Ion Exchange; Cresols; Depression, Chemical; Dihydroxyphenylalanine; Ethanol; Female; Fluorescence; Hydroxylamines; Isomerism; Liver; Mixed Function Oxygenases; NADP; Phenylalanine; Pteridines; Quaternary Ammonium Compounds; Rats; Stimulation, Chemical; Sulfates; Tyrosine	1971
Formation of meta-tyrosine form L-phenylalanine by beef adrenal medulla. A new biosynthetic route to catecholamines. Biochemical and biophysical research communications, 1971, Jul-02, Volume: 44, Issue:1 Topics: Adrenal Medulla; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Carbon Isotopes; Catecholamines; Cattle; Chromatography, Ion Exchange; Cresols; Dihydroxyphenylalanine; Female; Hydroxylamines; Iron; Kinetics; Methyltyrosines; Monoiodotyrosine; NAD; Phenols; Phenylalanine; Pteridines; Rats; Stereoisomerism; Tyrosine; Tyrosine 3-Monooxygenase	1971
Medical physiopathology, enzymology and diagnosis. Monographs in human genetics, 1972, Volume: 6 Topics: Amino Acid Metabolism, Inborn Errors; Ammonia; Homocystinuria; Humans; Intellectual Disability; Maple Syrup Urine Disease; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Pteridines; Tetrahydrofolate Dehydrogenase	1972
Phenylalanine hydroxylase in dilute lethal mice. Biochimica et biophysica acta, 1973, Jun-20, Volume: 313, Issue:1 Topics: Animals; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Genes, Lethal; Genotype; Homozygote; Kinetics; Liver; Mice; Mice, Inbred Strains; Mutation; Phenylalanine; Phenylalanine Hydroxylase; Pteridines; Time Factors	1973
Primary cultures of dissociated sympathetic neurons. II. Initial studies on catecholamine metabolism. The Journal of cell biology, 1973, Volume: 59, Issue:2 Pt 1 Topics: Animals; Ascorbic Acid; Catecholamines; Cells, Cultured; Dopamine; Ganglia, Autonomic; Kinetics; Neurons; Norepinephrine; Phenylalanine; Pteridines; Rats; Time Factors; Tyrosine	1973
Kidney phenylalanine hydroxylase from man and rat. Comparison with the liver enzyme. Biochemistry, 1974, Jan-01, Volume: 13, Issue:1 Topics: Animals; Binding Sites; Binding Sites, Antibody; Centrifugation, Density Gradient; Chromatography, Gel; Cross Reactions; Humans; Isoenzymes; Kidney; Kinetics; Liver; Organ Specificity; Phenylalanine; Phenylalanine Hydroxylase; Precipitin Tests; Pteridines; Rabbits; Rats; Species Specificity; Structure-Activity Relationship	1974
The non-enzymic hydroxylation of phenylalanine to tyrosine by 2-amino-4-hydroxy-6,7-dimethyl-5,6,7,8-tetrahydropteridine. The Biochemical journal, 1971, Volume: 125, Issue:2 Topics: Air; Carbon Isotopes; Catalase; Chemical Phenomena; Chemistry; Chromatography, Paper; Coenzymes; Cyanides; Dihydroxyphenylalanine; Edetic Acid; Hydrogen Peroxide; Hydroxylation; Iron; Peroxides; Phenylalanine; Phenylalanine Hydroxylase; Pteridines; Sulfhydryl Compounds; Tyrosine	1971
Stimulation of rat liver phenylalanine hydroxylase activity by derivatives of vitamin E. Biochemical and biophysical research communications, 1972, Sep-05, Volume: 48, Issue:5 Topics: Animals; Carbon Isotopes; Centrifugation; Humans; Kinetics; Liver; Male; Mixed Function Oxygenases; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Phosphoric Acids; Pteridines; Rats; Sodium Dodecyl Sulfate; Structure-Activity Relationship; Succinates; Tyrosine; Ultracentrifugation; Vitamin E	1972
Activation of phenylalanine hydroxylase by phenylalanine. Biochimica et biophysica acta, 1971, Aug-20, Volume: 242, Issue:2 Topics: Animals; Binding Sites; Centrifugation, Density Gradient; Dithiothreitol; Enzyme Activation; Kinetics; Liver; Macromolecular Substances; Mathematics; Mixed Function Oxygenases; Molecular Weight; Phenylalanine; Phenylalanine Hydroxylase; Pteridines; Rats; Temperature	1971
Phenylalanine hydroxylase of human liver: assay and some properties. Archives of biochemistry and biophysics, 1969, Volume: 134, Issue:1 Topics: Animals; Biopsy; Carbon Isotopes; Humans; Kinetics; Liver; Methods; Mixed Function Oxygenases; Phenylalanine; Pteridines; Rats	1969
A direct assay for liver phenylalanine hydroxylase. Biochimica et biophysica acta, 1969, Nov-04, Volume: 191, Issue:2 Topics: Alcohols; Animals; Catalase; Chemical Phenomena; Chemistry; Colorimetry; Fluorometry; Hydrogen-Ion Concentration; Kinetics; Liver; Methods; Mixed Function Oxygenases; Oxygen; Partial Pressure; Phenylalanine; Pteridines; Rats; Sulfur	1969
The effect of enzyme concentration, ionic strength, and temperature on the stoichiometry of the phenylalanine hydroxylase reaction. Biochemical and biophysical research communications, 1970, Feb-20, Volume: 38, Issue:4 Topics: Kinetics; Mixed Function Oxygenases; Osmolar Concentration; Phenylalanine; Pteridines; Temperature; Tyrosine	1970
A protein that stimulates rat liver phenylalanine hydroxylase. The Journal of biological chemistry, 1970, Sep-25, Volume: 245, Issue:18 Topics: Animals; Growth Hormone; Hydrogen-Ion Concentration; Kinetics; Liver; Mixed Function Oxygenases; Oxidoreductases; Phenylalanine; Phosphates; Proteins; Pteridines; Pterins; Rats	1970
Phenylalanine hydroxylase of Macaca irus. Purification of two components of the enzyme. Biochimica et biophysica acta, 1971, Apr-14, Volume: 235, Issue:1 Topics: Alcohols; Animals; Buffers; Calcium Phosphates; Chemical Precipitation; Chromatography, DEAE-Cellulose; Chromatography, Gel; Drug Stability; Electrophoresis; Ethanol; Hydrogen-Ion Concentration; Kinetics; Liver; Macaca; Methods; Mixed Function Oxygenases; Phenylalanine; Protamines; Pteridines; Quaternary Ammonium Compounds; Sulfates; Sulfhydryl Reagents; Sulfur; Sulfuric Acids	1971
The effect of variation of cofactor and substrate structure on the action of phenylalanine hydroxylase. Biochemical and biophysical research communications, 1968, Sep-06, Volume: 32, Issue:5 Topics: Animals; Chemical Phenomena; Chemistry; Kinetics; Liver; Mixed Function Oxygenases; Phenylalanine; Pteridines; Rats; Sheep; Tryptophan	1968
Phenylalanine hydroxylase activity towards two substrates simultaneously: enhancement of inhibition by phenylalanine, tryptophan and their derivatives. Biochimica et biophysica acta, 1968, Aug-27, Volume: 167, Issue:1 Topics: Animals; Binding Sites; Carbon Isotopes; Chemical Phenomena; Chemistry; Fluorine; Fluorometry; Kinetics; Liver; Mixed Function Oxygenases; Phenylalanine; Pteridines; Rats; Tryptophan	1968
Phenylalanine hydroxylation by Pseudomonas species (ATCC 11299a). Nature of the cofactor. The Journal of biological chemistry, 1969, Jan-10, Volume: 244, Issue:1 Topics: Chromatography; Chromatography, Gel; Chromatography, Paper; Dialysis; Fluorometry; Freeze Drying; Mixed Function Oxygenases; Phenylalanine; Phosphates; Pseudomonas; Pteridines; Pterins; Spectrophotometry; Tetroses; Threonine; Xanthopterin	1969
Further studies on tryptophan hydroxylase in rat brainstem and beef pineal. Biochemical pharmacology, 1969, Volume: 18, Issue:5 Topics: Animals; Brain Chemistry; Brain Stem; Catechols; Cattle; Dihydroxyphenylalanine; Dopamine; Hydrogen-Ion Concentration; Iron; Iron Chelating Agents; Methyltyrosines; Mixed Function Oxygenases; Norepinephrine; Phenylalanine; Pineal Gland; Pteridines; Pyruvates; Rats; Serum Albumin; Tryptophan	1969
Rat liver phenylalanine hydroxylase. A method for the measurement of activity, with particular reference to the distinctive features of the enzyme and the pteridine cofactor. European journal of biochemistry, 1969, Volume: 7, Issue:3 Topics: Animals; Ascorbic Acid; Catalase; Chemical Precipitation; Chromatography; Drug Stability; Kinetics; Liver; Methods; Mixed Function Oxygenases; Oxidation-Reduction; Phenylalanine; Pteridines; Rats; Spectrum Analysis; Temperature	1969
Coenzymes and hydroxylases: ascorbate and dopamine-beta-hydroxylase; tetrahydropteridines and phenylalanine and tyrosine hydroxylases. Pharmacological reviews, 1966, Volume: 18, Issue:1 Topics: Ascorbic Acid; Coenzymes; Dopamine; Mixed Function Oxygenases; Norepinephrine; Phenylalanine; Pteridines; Tyrosine	1966
Biosynthesis of pteridines and of phenylalanine hydroxylase cofactor in cell-free extracts of Pseudomonas species (ATCC 11299a). The Journal of biological chemistry, 1966, May-25, Volume: 241, Issue:10 Topics: Chromatography, Paper; Coenzymes; Formates; Guanine Nucleotides; In Vitro Techniques; Mixed Function Oxygenases; Phenylalanine; Pseudomonas; Pteridines	1966
The phenylalanine-hydroxylating system of avian liver. Pattern of appearance during embryonic development and limiting component. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1966, Volume: 123, Issue:2 Topics: Animals; Chick Embryo; In Vitro Techniques; Liver; Mixed Function Oxygenases; Phenylalanine; Pteridines; Rats	1966
Biopterin and folic acid deficiency. The American journal of clinical nutrition, 1967, Volume: 20, Issue:6 Topics: Anemia, Macrocytic; Animals; Blood Protein Electrophoresis; Chick Embryo; Diet; Female; Folic Acid Deficiency; Hemoglobins; Humans; Phenylalanine; Pregnancy; Pregnancy Complications, Hematologic; Pteridines; Reticulocytes; Vitamin B 12	1967
Phenylalanine hydroxylase from Pseudomonas species (ATCC 11299a). Purification of the enzyme and activation by various metal ions. The Journal of biological chemistry, 1967, Aug-25, Volume: 242, Issue:16 Topics: Cadmium; Chemical Phenomena; Chemistry; Chromatography; Copper; Hot Temperature; Iron; Mercury; Mixed Function Oxygenases; Molecular Weight; Oxygen; Phenylalanine; Pseudomonas; Pteridines; Tyrosine	1967
Reaction of Cu2+ and Fe3+ with tetrahydropteridines. Biochemical and biophysical research communications, 1967, Aug-07, Volume: 28, Issue:3 Topics: Copper; Ions; Iron; Organometallic Compounds; Oxidation-Reduction; Phenylalanine; Polarography; Pteridines	1967
Tyrosine hydroxylase inhibitors. Synthesis and activity of substituted aromatic amino acids. Journal of medicinal chemistry, 1967, Volume: 10, Issue:6 Topics: Adrenal Glands; Animals; Carbon Isotopes; Cattle; In Vitro Techniques; Oxidoreductases; Phenylalanine; Pteridines; Tyrosine	1967
The biosynthesis of 5-hydroxytryptamine in carcinoid tumours and intestine. Clinical science, 1967, Volume: 33, Issue:1 Topics: Adult; Animals; Carcinoid Tumor; Female; Humans; In Vitro Techniques; Intestine, Small; Male; Middle Aged; Mixed Function Oxygenases; Phenylalanine; Pteridines; Rabbits; Radioisotopes; Serotonin; Tryptophan	1967
Tetrahydropterin therapy for hyperphenylalaninemia caused by defective synthesis of tetrahydrobiopterin. Annals of neurology, 1983, Volume: 14, Issue:3 Topics: Biopterins; Blood Glucose; Child; Dose-Response Relationship, Drug; Growth Hormone; Humans; Male; Neurotransmitter Agents; Phenylalanine; Phenylketonurias; Prolactin; Pteridines; Pterins	1983
3,4-dihydroxystyrene, a novel microbial inhibitor for phenylalanine hydroxylase and other pteridine-dependent monooxygenases. Biochimica et biophysica acta, 1984, Sep-11, Volume: 789, Issue:2 Topics: Animals; Basidiomycota; Binding, Competitive; Liver; Phenylalanine; Phenylalanine Hydroxylase; Pteridines; Rats; Structure-Activity Relationship; Styrenes; Time Factors; Tryptophan Hydroxylase; Tyrosine 3-Monooxygenase	1984
Biopterin synthesis defects: problems in diagnosis. Pediatrics, 1984, Volume: 74, Issue:6 Topics: Biopterins; Diet; Female; Humans; Infant, Newborn; Metabolism, Inborn Errors; Neopterin; Neurotransmitter Agents; Phenylalanine; Pteridines	1984
Tetrahydrobiopterin metabolism in Down's syndrome and in non-Down's syndrome mental retardation. Journal of mental deficiency research, 1982, Volume: 26 (Pt 2) Topics: Adult; Aged; Biopterins; Down Syndrome; Female; Humans; Intellectual Disability; Male; Middle Aged; Phenylalanine; Pteridines	1982
[Development of the biosynthesis and excretion of pterins in phenylketonuria and its variants]. Archives francaises de pediatrie, 1983, Volume: 40 Suppl 1 Topics: Alcohol Oxidoreductases; Biopterins; Child; Chromatography, High Pressure Liquid; Humans; Phenylalanine; Phenylketonurias; Pteridines; Pterins	1983
[Biopterin synthesis defects: complete deficiencies (reductase and synthetase)]. Archives francaises de pediatrie, 1983, Volume: 40 Suppl 1 Topics: Alcohol Oxidoreductases; Biopsy, Needle; Biopterins; Child; Child, Preschool; Humans; Infant; Infant, Newborn; Liver; Phenylalanine; Phenylketonurias; Pteridines; Pterins	1983
[Partial deficiency of tetrahydrobiopterin]. Archives francaises de pediatrie, 1983, Volume: 40 Suppl 1 Topics: Adolescent; Alcohol Oxidoreductases; Biopterins; Child; Child, Preschool; Female; Humans; Infant, Newborn; Male; Phenylalanine; Phenylketonurias; Pteridines; Pterins	1983
Diagnostic and therapeutic aspects of dihydrobiopterin deficiency. Acta paediatrica Scandinavica, 1983, Volume: 72, Issue:3 Topics: 5-Hydroxytryptophan; Biopterins; Carbidopa; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Humans; Infant; Male; Nervous System Diseases; Phenylalanine; Phenylketonurias; Pteridines	1983
A defective enzyme in hyperphenylalaninaemia due to biopterin deficiency. Journal of inherited metabolic disease, 1983, Volume: 6, Issue:3 Topics: Adolescent; Adult; Alcohol Oxidoreductases; Biopterins; Child; Child, Preschool; Erythrocytes; Female; Humans; Infant; Infant, Newborn; Male; Middle Aged; Multienzyme Complexes; Neopterin; Phenylalanine; Pteridines	1983
Dihydropteridine reductase deficiency: non-response to oral tetrahydrobiopterin load test. Journal of inherited metabolic disease, 1984, Volume: 7, Issue:2 Topics: Biopterins; Female; Fibroblasts; Humans; Infant; Lymphocytes; NADH, NADPH Oxidoreductases; Phenylalanine; Phenylketonurias; Pteridines; Tyrosine	1984
Combined tetrahydrobiopterin-phenylalanine loading test in the detection of partially defective biopterin synthesis. European journal of pediatrics, 1984, Volume: 142, Issue:2 Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Biopterins; Child; Child, Preschool; Electroencephalography; Female; Humans; Neopterin; Phenylalanine; Pteridines	1984
The effect of ligands of phenylalanine 4-monooxygenase on the cAMP-dependent phosphorylation of the enzyme. The Journal of biological chemistry, 1984, Sep-25, Volume: 259, Issue:18 Topics: Adenosine Diphosphate; Animals; Biopterins; Kinetics; Magnesium; Phenylalanine; Phenylalanine Hydroxylase; Phosphorylation; Protein Kinases; Pteridines; Rats; Time Factors	1984
Significantly lower mean plasma total biopterin in 18 patients with senile dementia of Alzheimer type. Journal of neurology, neurosurgery, and psychiatry, 1984, Volume: 47, Issue:9 Topics: Aged; Alzheimer Disease; Biopterins; Creatinine; Humans; Phenylalanine; Pteridines	1984
Dihydrobiopterin biosynthesis deficiency. European journal of pediatrics, 1983, Volume: 141, Issue:2 Topics: Biopterins; Female; Humans; Infant; Infant, Newborn; Metabolism, Inborn Errors; Neopterin; Phenylalanine; Pteridines	1983
Blood spots on Guthrie cards can be used for inherited tetrahydrobiopterin deficiency screening in hyperphenylalaninaemic infants. Archives of disease in childhood, 1984, Volume: 59, Issue:1 Topics: Adolescent; Adult; Biopterins; Child; Child, Preschool; Dihydropteridine Reductase; Humans; Infant, Newborn; Methods; Phenylalanine; Phenylketonurias; Pteridines; Specimen Handling	1984
Ligand effects on the phosphorylation state of hepatic phenylalanine hydroxylase. The Journal of biological chemistry, 1984, Feb-25, Volume: 259, Issue:4 Topics: Animals; Biopterins; Enzyme Activation; Kinetics; Ligands; Liver; Male; Phenylalanine; Phenylalanine Hydroxylase; Phosphorylation; Protein Kinases; Pteridines; Rats; Rats, Inbred Strains	1984
Current status of biopterin screening. The Journal of pediatrics, 1984, Volume: 104, Issue:4 Topics: Biopterins; Chromatography, High Pressure Liquid; Humans; Infant; Infant, Newborn; Mass Screening; Neopterin; Phenylalanine; Phenylketonurias; Pteridines	1984
GTP cyclohydrolase I deficiency, a new enzyme defect causing hyperphenylalaninemia with neopterin, biopterin, dopamine, and serotonin deficiencies and muscular hypotonia. European journal of pediatrics, 1984, Volume: 141, Issue:4 Topics: Adolescent; Aminohydrolases; Biopterins; Child; Child, Preschool; Dopamine; Female; GTP Cyclohydrolase; Humans; Infant; Liver; Metabolism, Inborn Errors; Muscle Hypotonia; Neopterin; Phenylalanine; Pteridines; Serotonin	1984
Pterin metabolism in normal subjects and hyperphenylalaninaemic patients. Journal of inherited metabolic disease, 1981, Volume: 4, Issue:2 Topics: Adult; Alcohol Oxidoreductases; Biopterins; Child; Child, Preschool; Chromatography, High Pressure Liquid; Humans; Infant; NADH, NADPH Oxidoreductases; Neopterin; Phenylalanine; Phenylketonurias; Pteridines; Pterins; Xanthopterin	1981
A case of tetrahydrobiopterin deficiency due to a defective synthesis of dihydrobiopterin. Journal of inherited metabolic disease, 1982, Volume: 5, Issue:2 Topics: Biopterins; Humans; Infant; Male; Phenylalanine; Pteridines	1982
Serum Crithidia levels in disease. Biochemical medicine, 1980, Volume: 23, Issue:1 Topics: Adolescent; Adult; Aged; Biopterins; Celiac Disease; Child; Child, Preschool; Dementia; Female; Growth Substances; Humans; Infant; Leukemia, Lymphoid; Male; Middle Aged; Phenylalanine; Pteridines	1980
Diagnosis of variants of hyperphenylalaninemia by determination of pterins in urine. Clinica chimica acta; international journal of clinical chemistry, 1981, Mar-05, Volume: 110, Issue:2-3 Topics: Adolescent; Adult; Alcohol Oxidoreductases; Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Chromatography, High Pressure Liquid; Humans; NADH, NADPH Oxidoreductases; Phenylalanine; Phenylketonurias; Pteridines; Pterins; Spectrometry, Fluorescence	1981
Atypical phenylketonuria with defective biopterin metabolism. Monotherapy with tetrahydrobiopterin or sepiapterin, screening and study of biosynthesis in man. European journal of pediatrics, 1982, Volume: 138, Issue:2 Topics: Biopterins; Child, Preschool; Female; Humans; Neopterin; Phenylalanine; Phenylketonurias; Pteridines; Pterins; Serotonin	1982
Use of tetrahydropterins in the treatment of hyperphenylalaninemia due to defective synthesis of tetrahydrobiopterin: evidence that peripherally administered tetrahydropterins enter the brain. Pediatrics, 1982, Volume: 70, Issue:3 Topics: Biopterins; Brain; Child; Child, Preschool; Female; Humans; Male; Neopterin; Phenylalanine; Phenylketonurias; Pteridines; Pterins	1982
Developmental aspects of pteridine metabolism and relationships with phenylalanine metabolism. Clinica chimica acta; international journal of clinical chemistry, 1981, Oct-26, Volume: 116, Issue:2 Topics: Adolescent; Adult; Aging; Amniotic Fluid; Animals; Biopterins; Child; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Male; Neopterin; Phenylalanine; Phenylketonurias; Pregnancy; Pteridines; Rats; Rats, Inbred Strains	1981
Early diagnosis of hyperphenylalaninemia due to tetrahydrobiopterin deficiency (malignant hyperphenylalaninemia). The Journal of pediatrics, 1980, Volume: 96, Issue:5 Topics: Biopterins; Humans; Infant, Newborn; Phenylalanine; Phenylketonurias; Pteridines	1980
Hyperphenylalaninemia due to dihydropteridine reductase deficiency: diagnosis by measurement of oxidized and reduced pterins in urine. Pediatrics, 1980, Volume: 65, Issue:4 Topics: Adult; Biopterins; Child; Diagnosis, Differential; Humans; Methods; NADH, NADPH Oxidoreductases; Phenylalanine; Phenylketonurias; Pteridines	1980
Progress in phenylketonuria: defects in the metabolism of biopterin. Pediatrics, 1980, Volume: 65, Issue:4 Topics: Biopterins; Child; Humans; Infant; Infant, Newborn; Phenylalanine; Phenylketonurias; Pteridines	1980
Biopterin defect in a normal-appearing child affected by a transient phenylketonuria. Archives of disease in childhood, 1980, Volume: 55, Issue:8 Topics: Biopterins; Child, Preschool; Diagnosis, Differential; Humans; Infant; Male; Phenylalanine; Phenylketonurias; Pteridines	1980
Neopterin and biopterin levels in patients with atypical forms of phenylketonuria. Journal of neurochemistry, 1980, Volume: 35, Issue:4 Topics: Amino Acid Metabolism, Inborn Errors; Biopterins; Chromatography, High Pressure Liquid; Humans; Liver; Neopterin; Phenylalanine; Phenylketonurias; Pteridines	1980
[A case report of mild from of phenylketonuria]. Rinsho shinkeigaku = Clinical neurology, 1996, Volume: 36, Issue:5 Topics: Adult; Biomarkers; Humans; Intellectual Disability; Male; Phenylalanine; Phenylketonurias; Pteridines; Tremor	1996
Phenylalanine hydroxylase from Chromobacterium violaceum. Uncoupled oxidation of tetrahydropterin and the role of iron in hyroxylation. The Journal of biological chemistry, 1998, Oct-02, Volume: 273, Issue:40 Topics: Amino Acid Sequence; Bacterial Proteins; Chromobacterium; Cloning, Molecular; Copper; Escherichia coli; Hydrogen Peroxide; Hydroxylation; Iron; Kinetics; Metalloproteins; Metals; Molecular Sequence Data; Molecular Structure; Oxygen; Phenylalanine; Phenylalanine Hydroxylase; Pteridines; Recombinant Proteins; Sequence Alignment; Sequence Analysis; Spectrophotometry; Sulfhydryl Compounds	1998
Juvenile form of dihydropteridine reductase deficiency in 2 Tunisian patients. Neuropediatrics, 1998, Volume: 29, Issue:6 Topics: Adult; Age of Onset; Child; Consanguinity; Disease Progression; Follow-Up Studies; Humans; Male; Metabolism, Inborn Errors; Movement Disorders; Neurodegenerative Diseases; Nuclear Family; Phenylalanine; Phenylketonurias; Pteridines	1998
Molybdopterin synthase mutations in a mild case of molybdenum cofactor deficiency. American journal of medical genetics, 2001, Nov-22, Volume: 104, Issue:2 Topics: Alleles; Base Sequence; Brain; Child, Preschool; Coenzymes; DNA Mutational Analysis; DNA, Complementary; Exons; Female; Glutamine; Heterozygote; Humans; Introns; Magnetic Resonance Imaging; Metalloproteins; Models, Chemical; Molecular Sequence Data; Molybdenum Cofactors; Mutation; Phenylalanine; Pteridines; Sulfurtransferases	2001
Bacterial lipopolysaccharide down-regulates expression of GTP cyclohydrolase I feedback regulatory protein. The Journal of biological chemistry, 2002, Mar-22, Volume: 277, Issue:12 Topics: Alanine; Blotting, Northern; Cells, Cultured; Cloning, Molecular; DNA, Complementary; Dose-Response Relationship, Drug; Down-Regulation; Endothelium, Vascular; GTP Cyclohydrolase; Humans; Interferon-gamma; Intracellular Signaling Peptides and Proteins; Lipopolysaccharides; Phenylalanine; Protein Binding; Proteins; Pteridines; Pterins; Recombinant Proteins; RNA, Messenger; Time Factors; Tissue Distribution; Tumor Cells, Cultured; Umbilical Veins; Up-Regulation	2002
The nature of the primary oxidation product formed from tetrahydropteridines during phenylalanine hydroxylation. The Journal of biological chemistry, 1961, Volume: 236 Topics: Folic Acid; Humans; Hydroxylation; Oxidation-Reduction; Phenylalanine; Pteridines	1961
STUDIES ON THE STRUCTURE OF THE PRIMARY OXIDATION PRODUCT FORMED FROM TETRAHYDROPTERIDINES DURING PHENYLALAMINE HYDROXYLATION. The Journal of biological chemistry, 1964, Volume: 239 Topics: Fluorescence; Freeze Drying; Hydroxylation; Mixed Function Oxygenases; NADP; Oxidation-Reduction; Phenylalanine; Proteins; Pteridines; Pterins; Research; Tritium	1964
THE ROLE OF PTERIDINES IN THE ENZYMATIC CONVERSION OF PHENYLALANINE TO TYROSINE. Transactions of the New York Academy of Sciences, 1964, Volume: 26 Topics: Coenzymes; Dihydroxyphenylalanine; Humans; Liver; Metabolism; Nucleotides; Phenylalanine; Pteridines; Pterins; Tyrosine	1964
[EXPERIMENTAL ALTERATION OF DROSOPTERIN SYNTHESIS IN THE DROSOPHILA MUTANTS ROSY AND MAROON-LIKE]. Zeitschrift fur Naturforschung. Teil B, Chemie, Biochemie, Biophysik, Biologie und verwandte Gebiete, 1965, Volume: 20 Topics: Animals; Drosophila; Mutation; Pharmacology; Phenylalanine; Pigments, Biological; Pteridines; Research	1965
Lessons from 30 years of selective screening for tetrahydrobiopterin deficiency. Journal of inherited metabolic disease, 2010, Volume: 33, Issue:Suppl 2 Topics: Biomarkers; Biopterins; Dihydropteridine Reductase; GTP Cyclohydrolase; Humans; Hydro-Lyases; Infant, Newborn; Metabolism, Inborn Errors; Neonatal Screening; Phenylalanine; Phenylketonurias; Predictive Value of Tests; Prognosis; Pteridines	2010
Structural analysis of human dihydrofolate reductase as a binary complex with the potent and selective inhibitor 2,4-diamino-6-{2'-O-(3-carboxypropyl)oxydibenz[b,f]-azepin-5-yl}methylpteridine reveals an unusual binding mode. Acta crystallographica. Section D, Biological crystallography, 2011, Volume: 67, Issue:Pt 10 Topics: Ammonium Sulfate; Animals; Benzazepines; Catalytic Domain; Crystallization; Crystallography, X-Ray; Folic Acid Antagonists; Humans; Mice; Models, Molecular; Phenylalanine; Protein Conformation; Pteridines; Tetrahydrofolate Dehydrogenase	2011
Stress Hyperphenylalaninemia Is Associated With Mortality in Cardiac ICU: Clinical Factors, Genetic Variants, and Pteridines. Critical care medicine, 2022, 11-01, Volume: 50, Issue:11 Topics: Adult; APACHE; Humans; Intensive Care Units; Phenylalanine; Prognosis; Prospective Studies; Pteridines; Young Adult	2022