pteridines has been researched along with neopterin in 172 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 109 (63.37) | 18.7374 |
| 1990's | 37 (21.51) | 18.2507 |
| 2000's | 23 (13.37) | 29.6817 |
| 2010's | 1 (0.58) | 24.3611 |
| 2020's | 2 (1.16) | 2.80 |
| Authors | Studies |
|---|---|
| Eto, I; Fukushima, K; Shiota, T | 1 |
| Hirayama, K; Katoh, S; Masuda, I; Nakanishi, N; Sueoka, T; Yamada, S | 1 |
| Icho, T; Kajiwara, Y; Kojima, S; Kubota, K | 1 |
| Reibnegger, G; Werner, ER; Werner-Felmayer, G | 1 |
| Ambach, E; Bodner, E; Fuchs, D; Glaser, K; Kronberger, P; Wachter, H; Weiss, G | 1 |
| Fuchs, D; Hausen, A; Reibnegger, G; Wachter, H; Werner, ER; Werner-Felmayer, G | 1 |
| Dierich, MP; Fuchs, D; Hausen, A; Reibnegger, G; Wachter, H; Werner, ER; Werner-Felmayer, G | 1 |
| Fuchs, D; Reibnegger, G; Wachter, H; Werner, ER | 1 |
| Dierich, MP; Fuchs, D; Möst, J; Sölder, B; Wachter, H; Weyrer, W | 1 |
| Curtius, HC; Dahinden, R; Ghisla, S; Kuster, T; Leimbacher, W; Raschdorf, F; Richter, WJ; Steinerstauch, P | 1 |
| Hofbauer, J; Kratzik, C; Kuzmits, R; Legenstein, E; Ludwig, H; Szekeresz, T | 1 |
| Bacher, A; Katzenmaier, G; Kerler, F; Le Van, Q; Schmid, C; Schwarzkopf, B; Ziegler, I | 1 |
| Fuchs, D; Goedert, JJ; Kaufman, S; Krämer, A; Milstien, S; Reibnegger, G; Wachter, H; Werner, ER | 1 |
| Katoh, S; Matsuura, S; Sueoka, T; Sugimoto, T | 1 |
| Ferre, J; Jacobson, KB; Naylor, EW | 1 |
| Beth-Giraldo, E; Chirianni, A; De Mercato, R; Giraldo, G; Levy, JA; Marfella, A; Nitsch, F; Perna, M; Piazza, M; Santelli, G | 1 |
| Abita, JP; Cost, H; Kaufman, S; Milstien, S; Saimot, G | 1 |
| Gerstner, L; Haas, R | 1 |
| Albert, E; Fuchs, D; Hausen, A; Huber, C; Margreiter, R; Niederwieser, D; Reibnegger, G; Schönitzer, D; Troppmair, J; Wachter, H | 1 |
| Curtius, HC; Heintel, D; Leimbacher, W; Redweik, U; Zagalak, B | 1 |
| Curtius, HC; Leimbacher, W; Leupold, D; Niederwieser, A; Ponzone, A; Rey, F | 1 |
| Bettex, JD; Blau, N; Hirschel, B; Joller, P; Lüthy, R; Niederwieser, A; Prader, A; Schaedelin, J; Seger, R; Vetter, U | 1 |
| Flener, R; Huber, C; Kovarik, J; Leiter, E; Margreiter, R; Pohanka, E; Schwarz, M; Troppmair, J; Woloszczuk, W | 1 |
| Borchert, M; Seidl, J; Ziegler, I | 1 |
| Fuchs, D; Hausen, A; Reibnegger, G; Wachter, H; Werner, ER | 1 |
| Fuchs, D; Hausen, A; Pilz, P; Reibnegger, G; Wachter, H; Wessely, K | 1 |
| Bacher, A; Katzenmeier, G; Le Van, Q; Schmid, C; Schwarzkopf, B | 1 |
| Alam, A; Shen, RS; Zhang, YX | 1 |
| Bosshard, R; Leimbacher, W; Neuheiser, F; Redweik, U; Zagalak, B | 1 |
| Blair, JA; Heales, SJ; Meinschad, C; Ziegler, I | 1 |
| Diezel, W; Falck, P; Rabe, H; Sönnichsen, N; Volk, HD; von Baehr, R | 1 |
| Daniel, V; Dreikorn, K; Opelz, G; Schäfer, AJ | 1 |
| Bollbach, R; Fuchs, D; Hausen, A; Judmaier, G; Niederwieser, D; Prior, C; Reibnegger, G; Rotthauwe, HW; Wachter, H; Werner, ER | 1 |
| Burns, RS; Eldridge, R; Levine, RA; LeWitt, PA; Lovenberg, W; Miller, LP; Newman, RP; Papavasiliou, A; Rayes, A | 1 |
| Abate, G; Comella, P; Marfella, A; Nitsch, F; Perna, M; Santelli, G | 1 |
| Akino, M; Horikoshi, T; Masada, M; Matsuura, S; Nagatsu, T; Sawada, M; Sugimoto, T | 1 |
| Andrysek, O; Cernovská, I; Vasícková, M; Zitko, M | 1 |
| Hakola, M; Hannonen, P; Möttönen, T; Oka, M; Tikanoja, S; Viinikka, L | 1 |
| Egg, D; Fuchs, D; Günther, R; Hausen, A; Reibnegger, G; Wachter, H; Werner, ER | 1 |
| Delcroix, M; Dhondt, JL; Farriaux, JP; Forzy, G; Hayte, JM | 1 |
| Applegarth, DA; Davidson, AG; Ennis, D; Naylor, EW; Niederwieser, A; Wong, LT | 1 |
| Boudha, A; Dhondt, JL; Farriaux, JP; Largillière, C; Leeming, RJ; Ringel, J; Roger, MM | 1 |
| Aulitzky, W; Frick, J; Fuchs, D; Hausen, A; Joos, H; Reibnegger, G; Wachter, H | 1 |
| Balemans, MG; de Morée, A; Ebels, I; Mans, DR; van Benthem, J | 1 |
| Ekman, P; Eneroth, P; Eriksson, A; Lewenhaupt, A; Nordström, L | 1 |
| Akino, M; Katoh, S; Masada, M; Sueoka, T | 1 |
| Fuchs, D; Hausen, A; Huber, C; König, P; Margreiter, R; Reibnegger, G; Wachter, H | 1 |
| Bontoux, D; Bounaud, MP; Mura, P; Reiss, D; Tallineau, C; Thomas, P | 1 |
| Krungkrai, J; Webster, HK; Yuthavong, Y | 1 |
| Brown, GM; Switchenko, AC | 1 |
| Curtius, HC; Ghisla, S; Heintel, D; Kuster, T; Leimbacher, W; Niederwieser, A | 1 |
| Güttler, F; Lou, HC; Lykkelund, C; Niederwieser, A; Rasmussen, V | 1 |
| Ziegler, I | 1 |
| Bichler, AH; Dapunt, O; Fuchs, DN; Fuith, LC; Hausen, A; Hetzel, HM; Lutz, H; Reibnegger, GJ; Wachter, H; Werner, ER | 1 |
| Gaull, GE; Matsubara, Y | 1 |
| Aulitzky, W; Frick, J; Fuchs, D; Hausen, A; Reibnegger, G; Wachter, H | 1 |
| Cotlier, E; Rao, GN | 1 |
| Kaufman, S; Milstien, S | 1 |
| Bichler, A; Fuchs, D; Hausen, A; Hetzel, H; Reibnegger, G; Wachter, H | 3 |
| Fuchs, D; Hausen, A; Huber, C; Judmaier, G; Niederwieser, D; Reibnegger, G; Wachter, H | 1 |
| Duch, DS; Garbutt, JC; Nichol, CA; Woolf, JH | 1 |
| Fuchs, D; Granditsch, G; Hausen, A; Reibnegger, G; Wachter, H | 1 |
| Hanley, WB; Kapatos, G; Kaufman, S; MacGregor, D; McInnes, RR; Milstien, S; Soldin, S; Van Loon, GR; Walsh, P; Warsh, JJ | 1 |
| Berlow, S; Hoganson, G; Kaufman, S; Matalon, R; Milstien, S; Naylor, E; Schuett, V; Seifert, W | 1 |
| Balemans, MG; de Moree, A; Ebels, I; Legerstee, WC; Noteborn, HJ; Van Benthem, J | 1 |
| Balemans, MG; de Moreé, A; Ebels, I; Hendriks, HG; van Berlo, M | 1 |
| Fuchs, D; Hausen, A; Huber, C; Margreiter, R; Reibnegger, G; Spielberger, M; Wachter, H | 2 |
| Dietrich, M; Kern, P; Rokos, H | 1 |
| Matsuura, S; Nagatsu, T; Sawada, M; Sugimoto, T; Yamaguchi, T | 1 |
| Ferre, J; Jacobson, KB | 1 |
| Bannert, P; Fuchs, D; Gratwohl, A; Hausen, A; Huber, C; Niederwieser, D; Reibnegger, G; Speck, B; Wachter, H | 1 |
| Brown, GM; Paton, DR; Wiederrecht, GJ | 1 |
| Akino, M; Arashima, S; Kawaguchi, M; Masada, M; Matsuo, N; Mizokami, T; Seki, T; Tsuchiya, T; Yoshida, T; Yoshioka, S | 1 |
| Brown, GM; Primus, JP; Switchenko, AC | 1 |
| Batchelor, JR; Fuchs, D; Hausen, A; Huber, C; Lang, A; Niederwieser, D; Reibnegger, G; Swetly, P; Troppmair, J; Wachter, H | 1 |
| Ebels, I; l'Hélias, C; Proust, J; Salemink, CA | 1 |
| Brown, GM; Wiederrecht, GJ | 1 |
| Güttler, F; Lou, H; Lykkelund, C; Niederwieser, A | 1 |
| Boonpucknavig, V; Fuchs, D; Hausen, A; Reibnegger, G; Schmutzhard, E; Wachter, H | 1 |
| Bowers, SW; Duch, DS; Nichol, CA; Woolf, JH | 1 |
| Akino, M; Matsuura, S; Nagatsu, T; Nakazawa, N; Ogawa, H; Sawada, M; Sugimoto, T; Yamaguchi, T | 1 |
| Fuchs, D; Hausen, A; Huber, C; Reibnegger, G; Wachter, H | 1 |
| Fuchs, D; Hausen, A; Kofler, M; Kosanowski, H; Reibnegger, G; Wachter, H | 1 |
| Fuchs, D; Hausen, A; Reibnegger, G; Wachter, H | 1 |
| Davidson, JR; Duch, DS; Garbutt, JC; Nichol, CA; Woolf, JH | 1 |
| Huber, C; Niederwieser, D; Wachter, H | 1 |
| Fuchs, D; Hausen, A; Huber, C; Niederwieser, D; Nilsson, K; Reibnegger, G; Wachter, H | 1 |
| Fuchs, D; Hausen, A; Huber, C; Knosp, O; Reibnegger, G; Spira, TJ; Wachter, H | 1 |
| Nichol, CA; Smith, GK | 1 |
| Dhondt, JL; Farriaux, JP; Largilliere, C; Leeming, RJ; Leroux, B | 1 |
| Heininger, JA; Lin, YY; Matsubara, Y | 1 |
| Bellahsene, Z; Dhondt, JL; Farriaux, JP | 1 |
| Fuchs, D; Hausen, A; Reibnegger, G; Reissigl, H; Schönitzer, D; Spira, T; Wachter, H | 1 |
| Matalon, R | 1 |
| Atarés, M; Blau, N; Cardesa-Garcia, J; Joller, P; Niederwieser, A; Wang, M | 1 |
| Wainwright, LK; Wainwright, SD | 1 |
| Barford, PA; Blair, JA; Eggar, C; Hamon, C; Morar, C; Whitburn, SB | 1 |
| Smith, RA; Stea, B | 1 |
| Ardouin, P; Dautrevaux, M; Dhondt, JL; Farriaux, JP; Largilliere, C | 1 |
| Akino, M; Inoue, K; Masada, M; Mizokami, T; Yoshida, T; Yoshioka, SI | 1 |
| Blau, N; Niederwieser, A | 1 |
| Duch, DS; Nichol, CA; Woolf, JH | 1 |
| Fukushima, T | 1 |
| Fuchs, D; Hausen, A; König, K; Wachter, H | 1 |
| Fuchs, D; Grünewald, K; Hausen, A; Huber, H; König, K; Wachter, H | 2 |
| Bichler, A; Fuchs, D; Hausen, A; Hetzel, H; König, K; Wachter, H | 1 |
| Curtius, HC; Leupold, D; Niederwieser, A; Wang, M | 1 |
| Kapatos, G; Kaufman, S; McInnes, RR; Rizzo, WB; Schulman, JD | 1 |
| Dorsett, D; Flanagan, JM; Jacobson, KB | 1 |
| Ardouin, P; Dhondt, JL; Farriaux, JP; Hayte, JM | 1 |
| Frisius, H; Kirstaedter, HJ; Rokos, H; Rokos, K | 1 |
| Bartholomé, K; Kaufman, S; Lee, CL; Milstien, S; Nixon, JC | 1 |
| Esterbauer, H; Gieseg, SP; Reibnegger, G; Wachter, H | 1 |
| Bacher, A; Huber, R; Meining, W; Nar, H; Schmid, C; Weinkauf, S | 1 |
| Baier-Bitterlich, G; Fuchs, D; Hausen, A; Murr, C; Reibnegger, G; Wachter, H; Werner, ER; Werner-Felmayer, G | 1 |
| Fuchs, D; Hausen, A; Reibnegger, G; Schmidt, K; Wachter, H; Weiss, G; Werner, ER; Werner-Felmayer, G | 1 |
| Baier-Bitterlich, G; Böck, G; Dierich, MP; Fuchs, D; Murr, C; Reibnegger, G; Sgonc, R; Wachter, H; Werner-Felmayer, G | 1 |
| De Saizieu, A; van Loon, AP; Vankan, P | 1 |
| Fuchs, D; Grunicke, HH; Schubert, C; Uberall, F; Wachter, H; Werner-Felmayer, G | 1 |
| Dierich, MP; Fuchs, D; Hausen, A; Reibnegger, G; Semenitz, E; Wachter, H; Weiss, G; Werner, ER; Werner-Felmayer, G | 1 |
| Fuchs, D; Lang, F; Wachter, H; Weiss, G; Wöll, E | 1 |
| Fuchs, D; Grote, J; Hoffmann, G; Schobersberger, W; Wachter, H | 1 |
| Baier-Bitterlich, G; Fuchs, D; Wachter, H | 2 |
| Baier-Bitterlich, G; Esterbauer, H; Fuchs, D; Murr, C; Pfleiderer, W; Wachter, H; Werner, ER | 1 |
| Baier, G; Baier-Bitterlich, G; Böck, G; Fuchs, D; Hausen, A; Pavelka, M; Utermann, G; Wachter, H | 1 |
| Baier-Bitterlich, G; Bock, G; Fuchs, D; Hobisch-Hagen, P; Hoffmann, G; Schobersberger, W; Volkl, H; Wachter, H; Wirleitner, B | 1 |
| Bacher, A; Eberhardt, S; Haussmann, C; Lottspeich, F; Mackamul, S; Rohdich, F; Scheuring, J | 1 |
| Baeuerle, PA; Baier, G; Baier-Bitterlich, G; Fresser, F; Fuchs, D; Uberall, F; Wachter, H; Werner, ER; Zangerle, R | 1 |
| Arai, T; Makino, K; Mori, H; Mori, K; Nakao, S; Suzuki, T; Tajima, K; Watanabe, K | 1 |
| Baier-Bitterlich, G; Fuchs, D; Hoffmann, G; Schobersberger, W; Wachter, H; Wirleitner, B | 1 |
| Dikalov, S; Freisleben, HJ; Mlekusch, W; Oettl, K; Reibnegger, G | 1 |
| Howell, DM; White, RH | 1 |
| Baier-Bitterlich, G; Fuchs, D; Wede, I; Widner, B; Wirleitner, B | 1 |
| Durán-Merás, I; Espinosa-Mansilla, A; Salinas, F | 1 |
| Baier-Bitterlich, G; Böck, G; Fuchs, D; Widner, B; Wirleitner, B | 1 |
| Oettl, K; Reibnegger, G | 1 |
| Auerbach, G; Bacher, A; Boyle, P; Bracher, A; Eisenreich, W; Fischer, M; Gentili, P; Huber, R; Nar, H; Ritz, H; Schramek, N | 1 |
| Fandrey, J; Fuchs, D; Jelkmann, W; Pagel, H; Schobersberger, W | 1 |
| Baier-Bitterlich, G; Fuchs, D; Grammer, T; Oettl, K; Reibnegger, G; Wirleitner, B | 1 |
| Fuchs, D; Wede, I; Widner, B | 1 |
| Gieseg, SP; Glubb, D; Maghzal, G | 2 |
| Fuchs, D; Mayr, C; Widner, B; Wirleitner, B | 1 |
| Bacher, A; Bracher, A; Schramek, N | 1 |
| Dierich, MP; Fuchs, D; Lass-Flörl, C; Mohsenipour, I; Speth, C; Stöckl, G; Widner, B; Wirleitner, B; Würzner, R | 1 |
| Baier, G; Baier-Bitterlich, G; Böck, G; Czaputa, R; Fuchs, D; Oettl, K; Reibnegger, G; Widner, B; Wirleitner, B | 1 |
| Duggan, S; Gebicki, JM; Gieseg, SP; Rait, C | 1 |
| Gieseg, SP; Glubb, D; Rait, C; Whybrow, J | 1 |
| Baier-Bitterlich, G; Böck, G; Enzinger, C; Fuchs, D; Wirleitner, B | 1 |
| Auerbach, G; Bacher, A; Bracher, A; Fischer, M; Huber, R; Nar, H; Schramek, N | 1 |
| Fuchs, D; Murr, C; Widner, B; Wirleitner, B | 1 |
| Baier, G; Baier-Bitterlich, G; Böck, G; Enzinger, C; Fuchs, D; Lutz, C; Tomaselli, B; Wirleitner, B | 1 |
| Hosoya, T; Nakayama, M; Sakagami, H; Tajima, M; Tokutome, G; Yokoyama, K; Yoshida, H | 1 |
| Horejsi, R; Jung, C; Möller, R; Reibnegger, G; Tafeit, E | 1 |
| Fuchs, D; Greilberger, J; Herpfer, I; Jürgens, G; Ledinski, G; Widner, B | 1 |
| Duggan, S; Gieseg, S; Platt, A; Rait, C | 1 |
| Auerbach, G; Bacher, A; Bader, G; Bracher, A; Fischer, M; Hösl, C; Huber, R; Kaiser, J; Nar, H; Rebelo, J; Schramek, N | 1 |
| Böck, G; Fuchs, D; Neurauter, G; Obermoser, G; Schennach, H; Sepp, N; Wirleitner, B | 1 |
| Fekkes, D; Hoekstra, R; Pepplinkhuizen, L; van de Wetering, BJ; Verhoeven, WM | 1 |
| Bannink, M; Eggermont, AM; Fekkes, D; Kruit, WH; Mulder, PG; Stoter, G; Van Gool, AR; van Ojik, HH | 1 |
| Gregory, JF; Hanson, AD; Hugenholtz, J; Klaus, SM; Sybesma, W; Wegkamp, A | 1 |
| Engin, AB; Sahin, G; Tuzun, D | 1 |
| Bandarian, V; McCarty, RM; Somogyi, A | 1 |
| Hunakova, L; Martinicky, D; Sikurova, L; Zvarik, M | 1 |
| Bartoli, F; Capogrosso, CA; Carrà, G; Cavaleri, D; Crocamo, C; Fuchs, D; Guzzi, P; Kishi, T; Misiak, B; Moretti, F; Riboldi, I; Rubin, RT | 1 |
| Aktuglu-Zeybek, C; Cansever, MS; Cebi, MN; Isat, E; Kiykim, E; Oge-Enver, E; Yilmaz, G; Zubarioglu, T | 1 |
6 review(s) available for pteridines and neopterin
| Article | Year |
|---|---|
Immune activation and the anaemia associated with chronic inflammatory disorders.
Topics: Anemia; Animals; Biopterins; Chronic Disease; Cytokines; Hematopoiesis; Humans; Immunity, Cellular; Inflammation; Interferon-gamma; Neopterin; Pteridines | 1991 |
Neopterins in clinical medicine.
Topics: Biopterins; Humans; Neopterin; Predictive Value of Tests; Pteridines | 1988 |
Biosynthesis of tetrahydrobiopterin in man.
Topics: Alcohol Oxidoreductases; Biopterins; Deuterium; Humans; In Vitro Techniques; Liver; Neopterin; Pteridines; Tetrahydrofolate Dehydrogenase | 1985 |
Urinary unconjugated pteridines: general considerations.
Topics: Animals; Biopterins; Cell Transformation, Neoplastic; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Cricetinae; Humans; Male; Mice; Neoplasms; Neopterin; Pteridines; Rats; Xanthopterin | 1982 |
Neopterin as a marker for immune system activation.
Topics: Animals; Biomarkers; Humans; Immune System; Infections; Neoplasms; Neopterin; Pteridines | 2002 |
Blood concentrations of neopterin and biopterin in subjects with depression: A systematic review and meta-analysis.
Topics: Biopterins; Depression; Depressive Disorder, Major; Humans; Neopterin; Pteridines | 2023 |
2 trial(s) available for pteridines and neopterin
| Article | Year |
|---|---|
Effect of light therapy on biopterin, neopterin and tryptophan in patients with seasonal affective disorder.
Topics: Adult; Biopterins; Female; Humans; Immunity, Cellular; Male; Middle Aged; Neopterin; Personality Inventory; Phototherapy; Pteridines; Reference Values; Seasonal Affective Disorder; Seasons; Serotonin; Tryptophan | 2003 |
Pegylated interferon-alpha2b treatment in melanoma patients: influence on amino acids, 5-hydroxyindolacetic acid and pteridine plasma concentrations.
Topics: Adult; Aged; Amino Acids; Biopterins; Drug Administration Schedule; Female; Humans; Hydroxyindoleacetic Acid; Injections, Subcutaneous; Interferon alpha-2; Interferon-alpha; Male; Melanoma; Middle Aged; Neopterin; Phenylalanine; Pilot Projects; Polyethylene Glycols; Pteridines; Randomized Controlled Trials as Topic; Recombinant Proteins; Time Factors; Tryptophan; Tyrosine | 2004 |
164 other study(ies) available for pteridines and neopterin
| Article | Year |
|---|---|
Enzymatic synthesis of biopterin from D-erythrodihydroneopterin triphosphate by extracts of kidneys from Syrian golden hamsters.
Topics: Animals; Biological Assay; Biopterins; Brain; Cricetinae; Eukaryota; Kidney; Kinetics; Liver; Lung; Mesocricetus; NAD; NADP; Neopterin; Organ Specificity; Organophosphorus Compounds; Oxidation-Reduction; Pteridines; Pterins; Spectrometry, Fluorescence | 1976 |
[Isolation and stereostructural determination of neopterin (2-amino-4-hydroxy-6-trihydroxypropyl pteridine) from Drosophila melanogaster (author's transl)].
Topics: Animals; Biopterins; Chromatography, Paper; Drosophila melanogaster; Neopterin; Pteridines | 1979 |
Neopterin as an endogenous antioxidant.
Topics: Alloxan; Animals; Antioxidants; Biopterins; Blood Glucose; Diabetes Mellitus, Experimental; Male; Mice; Neopterin; Pteridines; Superoxide Dismutase; Superoxides; Xanthine Oxidase | 1992 |
Enzymatic cleavage of guanosine triphosphate (GTP) by GTP cyclohydrolase I.
Topics: Biopterins; GTP Cyclohydrolase; Guanosine Triphosphate; Humans; Neopterin; Pteridines | 1992 |
Distinct distributions of D-erythro-neopterin in arteries and veins and its recovery by an enterohepatic circulation.
Topics: Adenocarcinoma; Adult; Aged; Arteries; Bile; Biopterins; Duodenal Ulcer; Enterohepatic Circulation; Feces; Humans; Liver; Male; Middle Aged; Neopterin; Pteridines; Stomach Neoplasms; Veins | 1992 |
Relationships between pteridine synthesis and tryptophan degradation.
Topics: Biopterins; Cells, Cultured; Enzyme Induction; Humans; Hydrolases; Interferon-gamma; Macrophages; NAD; Neopterin; Pteridines; Tryptophan; Tryptophan Oxygenase | 1991 |
Increased 7,8-dihydroneopterin and reduced methyl-group metabolism in HIV-1 infection.
Topics: Acquired Immunodeficiency Syndrome; Biological Availability; Child; Humans; Neopterin; Pteridines; Tetrahydrofolates | 1990 |
Production and characterization of a monoclonal antibody against neopterin.
Topics: Animals; Antibodies, Monoclonal; Antibody Specificity; Biopterins; Cross Reactions; Enzyme-Linked Immunosorbent Assay; Hybridomas; Mice; Neopterin; Pteridines; Radioimmunoassay | 1990 |
1H-NMR and mass spectrometric studies of tetrahydropterins. Evidence for the structure of 6-pyruvoyl tetrahydropterin, an intermediate in the biosynthesis of tetrahydrobiopterin.
Topics: Alcohol Oxidoreductases; Biopterins; Magnetic Resonance Spectroscopy; Mass Spectrometry; Models, Chemical; Neopterin; Oxidation-Reduction; Phosphorus-Oxygen Lyases; Pteridines; Pterins; Stereoisomerism | 1990 |
Neopterin as tumour marker serum and urinary neopterin concentrations in malignant diseases.
Topics: Adolescent; Adult; Aged; alpha-Fetoproteins; Biopterins; Chorionic Gonadotropin; Chromatography, High Pressure Liquid; Female; Humans; Male; Middle Aged; Neoplasms; Neopterin; Pteridines; Radioimmunoassay; Testicular Neoplasms | 1986 |
Biosynthesis of tetrahydrobiopterin: a sensitive assay of 6-pyruvoyltetrahydropterin synthase using [2'-3H]dihydroneopterin 3'-triphosphate as substrate.
Topics: Adsorption; Alcohol Oxidoreductases; Animals; Biopterins; Charcoal; Chemical Phenomena; Chemistry; Edetic Acid; Escherichia coli; Liver; Magnesium; Mice; Neopterin; Phosphorus-Oxygen Lyases; Pteridines; Tritium | 1989 |
Urinary neopterin concentrations vs total neopterins for clinical utility.
Topics: Acquired Immunodeficiency Syndrome; Adult; Antigens, CD; Biopterins; HIV Seropositivity; Homosexuality; Humans; Male; Neopterin; Pteridines; T-Lymphocytes | 1989 |
Biopterin and neopterin in human saliva.
Topics: Adult; Biopterins; Chromatography, High Pressure Liquid; Female; Humans; Male; Neopterin; Oxidation-Reduction; Potassium Permanganate; Pteridines; Pterins; Saliva; Sex Factors | 1989 |
Repetitive recycling of guanosine triphosphate cyclohydrolase I for synthesis of dihydroneopterin triphosphate.
Topics: Aminohydrolases; Escherichia coli; GTP Cyclohydrolase; Indicators and Reagents; Neopterin; Pteridines | 1989 |
Urinary neopterin, a useful marker for AIDS?
Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Biopterins; Humans; Neopterin; Pteridines | 1985 |
Urinary neopterin and biopterin levels in patients with AIDS and AIDS-related complex.
Topics: Acquired Immunodeficiency Syndrome; Adult; Biopterins; Humans; Neopterin; Pteridines | 1985 |
[Radioimmunological determination of neopterin in blood donors].
Topics: Adolescent; Adult; Biopterins; Blood Donors; Female; Humans; Male; Neopterin; Pteridines; Radioimmunoassay; Respiratory Tract Infections; Sex Factors; Virus Diseases | 1985 |
Neopterin release in human mixed lymphocyte culture: requirement of HLA-DR disparity.
Topics: Biopterins; Female; Histocompatibility Antigens Class II; HLA-DR Antigens; Humans; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Lymphocytes; Male; Neopterin; Phenotype; Pteridines; T-Lymphocytes, Helper-Inducer | 1985 |
Purification and properties of the phosphate eliminating enzyme involved in the biosynthesis of BH4 in man.
Topics: Biopterins; Humans; Isoelectric Point; Liver; Magnesium; Molecular Weight; NADP; Neopterin; Pteridines; Pyrophosphatases; Temperature; Time Factors | 1985 |
Atypical phenylketonuria with "dihydrobiopterin synthetase" deficiency: absence of phosphate-eliminating enzyme activity demonstrated in liver.
Topics: Adult; Alcohol Oxidoreductases; Biopterins; Chemical Phenomena; Chemistry; Child; Child, Preschool; Female; Humans; Infant; Liver; Male; Neopterin; Phenylketonurias; Pteridines; Pyrophosphatases | 1985 |
Neopterin in AIDs, other immunodeficiencies, and bacterial and viral infections.
Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Bacterial Infections; Biopterins; Child; Child, Preschool; Deltaretrovirus; Female; Homosexuality; Humans; Immunologic Deficiency Syndromes; Infant; Lymphatic Diseases; Male; Neopterin; Pteridines; Retroviridae Infections; Virus Diseases | 1986 |
Relationship of interferon-gamma and neopterin levels during stimulation with alloantigens in vivo and in vitro.
Topics: Acute Disease; Biopterins; Graft Rejection; Humans; Infections; Interferon-gamma; Isoantigens; Kidney Transplantation; Lymphocyte Activation; Neopterin; Phytohemagglutinins; Pteridines | 1986 |
Phorbol ester causes short term and transient accumulation of pteridines in T cells and in cell lines.
Topics: Biopterins; Cell Line; Humans; Kinetics; Lymphocyte Activation; Neopterin; Protein Kinase C; Pteridines; Receptors, Immunologic; Receptors, Interleukin-2; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1986 |
Simultaneous determination of neopterin and creatinine in serum with solid-phase extraction and on-line elution liquid chromatography.
Topics: Adult; Biopterins; Chromatography, High Pressure Liquid; Creatinine; Edetic Acid; Female; Ferric Compounds; Humans; Kidney Transplantation; Male; Middle Aged; Neopterin; Pteridines; Quality Control; Radioimmunoassay; Reference Values | 1987 |
[1st case of AIDS in Salzburg. Important diagnostic hint by determination of neopterin].
Topics: Acquired Immunodeficiency Syndrome; Austria; Biopterins; Blood Sedimentation; Humans; Lymphocytes; Male; Middle Aged; Neopterin; Pteridines; Respiratory Insufficiency; T-Lymphocytes, Helper-Inducer; T-Lymphocytes, Regulatory | 1985 |
Biosynthesis of biopterin. Studies on the mechanism of 6-pyruvoyltetrahydropteridine synthase.
Topics: Alcohol Oxidoreductases; Animals; Biopterins; Cattle; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Neopterin; Phosphorus-Oxygen Lyases; Pteridines; Pterins; Substrate Specificity | 1988 |
Inhibition of GTP cyclohydrolase I by pterins.
Topics: Aminohydrolases; Animals; Biopterins; Folic Acid; GTP Cyclohydrolase; Kinetics; Liver; Neopterin; Oxidation-Reduction; Pteridines; Pterins; Rats; Xanthopterin | 1988 |
Synthesis of enzymatically active D-7,8-dihydroneopterin-3'-triphosphate.
Topics: Biopterins; Methods; Neopterin; Pteridines | 1988 |
Inhibition of monocyte luminol-dependent chemiluminescence by tetrahydrobiopterin, and the free radical oxidation of tetrahydrobiopterin, dihydrobiopterin and dihydroneopterin.
Topics: Ascorbic Acid; Biopterins; Dithioerythritol; Free Radicals; Humans; Hydrogen Peroxide; In Vitro Techniques; Luminescent Measurements; Macrophages; Monocytes; Neopterin; Oxidation-Reduction; Pteridines | 1988 |
[Quantitative determination of neopterin concentration in urine--a parameter for the detection of the immunologic activity of T lymphocytes in skin diseases].
Topics: Biopterins; Chromatography, High Pressure Liquid; Humans; Lymphocyte Activation; Neopterin; Pteridines; Skin Diseases; T-Lymphocytes | 1986 |
Assessment of plasma neopterin in clinical kidney transplantation.
Topics: Biopterins; Blood Urea Nitrogen; Cortisone; Creatinine; Graft Rejection; Humans; Kidney; Kidney Transplantation; Neopterin; Pteridines; Radioimmunoassay; Time Factors | 1986 |
Urinary neopterin, a marker of clinical activity in patients with Crohn's disease.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Biopterins; Child; Crohn Disease; Female; Hematocrit; Humans; Male; Middle Aged; Neopterin; Pteridines; Regression Analysis | 1986 |
Tetrahydrobiopterin in dystonia: identification of abnormal metabolism and therapeutic trials.
Topics: Adult; Aged; Biopterins; Dystonia; Female; Humans; Male; Middle Aged; Neopterin; Pteridines | 1986 |
Urinary neopterin levels in hematologic malignancies.
Topics: Adolescent; Adult; Aged; Biopterins; Child; Female; Hodgkin Disease; Humans; Lymphoma; Male; Middle Aged; Multiple Myeloma; Neopterin; Pteridines | 1986 |
A sensitive assay of GTP cyclohydrolase I activity in rat and human tissues using radioimmunoassay of neopterin.
Topics: Aminohydrolases; Animals; Biopterins; Brain; Caudate Nucleus; GTP Cyclohydrolase; Humans; Male; Neopterin; Parkinson Disease; Pteridines; Radioimmunoassay; Rats; Rats, Inbred Strains; Tissue Distribution | 1986 |
Renal excretion of neopterine and biopterine in patients with malignant melanoma and Hodgkin's disease.
Topics: Biopterins; Chromatography, Thin Layer; Female; Hodgkin Disease; Humans; Kidney; Male; Melanoma; Neopterin; Pteridines | 1986 |
Urinary neopterin index as a measure of rheumatoid activity.
Topics: Adult; Arthritis, Rheumatoid; Biopterins; Bone Diseases; Diagnosis, Differential; Female; Humans; Joint Diseases; Male; Middle Aged; Neopterin; Pain; Pteridines | 1986 |
Urinary neopterin reflects clinical activity in patients with rheumatoid arthritis.
Topics: Aged; Arthritis, Rheumatoid; Biopterins; Blood Sedimentation; C-Reactive Protein; Female; Humans; Immunity, Cellular; Male; Middle Aged; Neopterin; Osteoarthritis; Pteridines; Rheumatoid Factor | 1986 |
Unconjugated pteridines in amniotic fluid during gestation.
Topics: Amniotic Fluid; Biopterins; Creatinine; Female; Fetus; Gestational Age; Humans; Neopterin; Pregnancy; Pteridines | 1986 |
Guanosine triphosphate cyclohydrolase I deficiency: early diagnosis by routine urine pteridine screening.
Topics: Aminohydrolases; Biopterins; Chromatography, High Pressure Liquid; Diagnosis, Differential; GTP Cyclohydrolase; Humans; Infant, Newborn; Liver; Male; Neopterin; Phenylalanine; Phenylketonurias; Pteridines | 1987 |
Neonatal hyperphenylalaninemia presumably caused by guanosine triphosphate-cyclohydrolase deficiency.
Topics: Aminohydrolases; Biopterins; GTP Cyclohydrolase; Humans; Infant, Newborn; Leukocyte Count; Liver; Male; Neopterin; Phenylalanine; Pteridines; Pterins; T-Lymphocytes | 1985 |
The value of urinary neopterin as an immunological parameter in patients with malignant tumors of the genitourinary tract.
Topics: Adolescent; Adult; Aged; Biopterins; Carcinoma, Renal Cell; Chromatography, High Pressure Liquid; Dysgerminoma; Female; Humans; Kidney Neoplasms; Macrophages; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Neopterin; Prognosis; Prostatic Neoplasms; Pteridines; T-Lymphocytes; Testicular Neoplasms; Urinary Bladder Neoplasms; Urogenital Neoplasms | 1985 |
The effect of reduced neopterin on the synthesis of several methylated indoles in the pineal gland of adult male golden hamsters, kept under standardized conditions.
Topics: 5-Hydroxytryptophan; Animals; Biopterins; Cricetinae; Indoles; Male; Melatonin; Mesocricetus; Methylation; Neopterin; Pineal Gland; Pteridines; Tryptophan | 1985 |
Serum levels of prostatic acid phosphatase (PAP), tissue polypeptide antigen (TPA), CA-50, neopterine and of osteocalcin in patients with prostatic carcinoma.
Topics: Acid Phosphatase; Aged; Antigens, Neoplasm; Antigens, Tumor-Associated, Carbohydrate; Biopterins; Calcium-Binding Proteins; Clinical Enzyme Tests; Clinical Laboratory Techniques; Enzyme-Linked Immunosorbent Assay; Humans; Male; Methods; Middle Aged; Neopterin; Osteocalcin; Peptides; Prostate; Prostatic Neoplasms; Pteridines; Radioimmunoassay; Tissue Polypeptide Antigen; Vitamin K | 1985 |
Dyspropterin, an intermediate formed from dihydroneopterin triphosphate in the biosynthetic pathway of tetrahydrobiopterin.
Topics: Alcohol Oxidoreductases; Biopterins; Catalysis; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Dihydropteridine Reductase; Hydroxylation; Neopterin; Oxidation-Reduction; Pteridines; Pterins; Spectrophotometry, Ultraviolet | 1985 |
Neopterin levels in long-term renal allograft recipients.
Topics: Biopterins; Female; Graft Survival; Humans; Kidney Transplantation; Male; Neopterin; Prognosis; Pteridines; Time Factors | 1985 |
[Value of the assay of urinary neopterin in multiple myeloma. Preliminary study].
Topics: Aged; beta 2-Microglobulin; Biopterins; Chromatography, High Pressure Liquid; Female; Humans; Immunoglobulin A; Immunoglobulin G; Male; Middle Aged; Multiple Myeloma; Neopterin; Pteridines | 1985 |
Guanosine triphosphate cyclohydrolase in Plasmodium falciparum and other Plasmodium species.
Topics: Aminohydrolases; Animals; Chromatography, High Pressure Liquid; Erythrocytes; Folic Acid; Formates; GTP Cyclohydrolase; Kinetics; Neopterin; Plasmodium; Plasmodium berghei; Plasmodium falciparum; Pteridines | 1985 |
The enzymatic conversion of dihydroneopterin triphosphate to tripolyphosphate and 6-pyruvoyl-tetrahydropterin, an intermediate in the biosynthesis of other pterins in Drosophila melanogaster.
Topics: Alcohol Oxidoreductases; Animals; Drosophila melanogaster; Kinetics; Magnesium; Neopterin; Phosphorus-Oxygen Lyases; Polyphosphates; Pteridines; Pterins | 1985 |
Biopterin, neopterin and tyrosine responses to combined oral phenylalanine and tetrahydrobiopterin loading tests in two normal children and in a girl with partial biopterin deficiency.
Topics: Administration, Oral; Biopterins; Child; Female; Humans; Neopterin; Phenylalanine; Pteridines; Tyrosine | 1985 |
Synthesis and interferon-gamma controlled release of pteridines during activation of human peripheral blood mononuclear cells.
Topics: Animals; Biopterins; Chromatography, High Pressure Liquid; DNA Replication; Humans; Interferon-gamma; Iodine; Mice; Monocytes; Neopterin; Pteridines; Pterins; Time Factors | 1985 |
Neopterin as a prognostic indicator in patients with carcinoma of the uterine cervix.
Topics: Adenocarcinoma; Adult; Biopterins; Carcinoma, Squamous Cell; Female; Follow-Up Studies; Humans; Immunity, Cellular; Leiomyosarcoma; Middle Aged; Neopterin; Prognosis; Pteridines; Uterine Cervical Neoplasms | 1986 |
Biopterin and neopterin in various milks and infant formulas.
Topics: Animals; Biopterins; Cats; Cattle; Chromatography, High Pressure Liquid; Female; Humans; Infant Food; Milk; Milk, Human; Neopterin; Pteridines; Rabbits; Rats; Species Specificity | 1985 |
Significance of urinary neopterin in patients with malignant tumors of the genitourinary tract.
Topics: Adolescent; Adult; Aged; Biopterins; Carcinoma, Renal Cell; Female; Humans; Kidney Neoplasms; Male; Middle Aged; Neopterin; Prostatic Neoplasms; Pteridines; Urinary Bladder Neoplasms; Urogenital Neoplasms | 1985 |
Biosynthesis of neopterin, sepiapterin, and biopterin in rat and human ocular tissues.
Topics: Animals; Biopterins; Ciliary Body; Eye; Humans; Iris; Lens, Crystalline; Neopterin; Pteridines; Pterins; Rats; Retina | 1985 |
Biosynthesis of tetrahydrobiopterin: conversion of dihydroneopterin triphosphate to tetrahydropterin intermediates.
Topics: Adrenal Medulla; Animals; Biopterins; Brain; Cattle; Chemical Phenomena; Chemistry; In Vitro Techniques; Kinetics; Liver; Neopterin; Pteridines; Pterins; Rats | 1985 |
Neopterin, a biochemical indicator of cellular immune reactions, in the detection and control of patients with neoplastic diseases.
Topics: Adolescent; Adult; Aged; Biopterins; Female; Humans; Immunity, Cellular; Male; Middle Aged; Neoplasms; Neopterin; Pteridines | 1985 |
Neopterin as a new biochemical marker in the clinical assessment of ulcerative colitis.
Topics: Adolescent; Adult; Biopterins; Colitis, Ulcerative; Female; Humans; Immunity, Cellular; Male; Middle Aged; Monitoring, Physiologic; Neopterin; Pteridines | 1985 |
Urinary biopterin and neopterin excretion and pituitary-adrenal activity in psychiatric patients.
Topics: Adult; Alcoholism; Biopterins; Depressive Disorder; Dexamethasone; Female; Humans; Male; Mental Disorders; Middle Aged; Neopterin; Personality Disorders; Pituitary-Adrenal System; Psychotic Disorders; Pteridines; Schizophrenia | 1985 |
Urinary neopterin excretion in coeliac disease.
Topics: Biopterins; Celiac Disease; Child; Chromatography, High Pressure Liquid; Glutens; Humans; Neopterin; Pteridines | 1983 |
Biopterin synthesis defect. Treatment with L-dopa and 5-hydroxytryptophan compared with therapy with a tetrahydropterin.
Topics: 5-Hydroxytryptophan; Amino Acid Metabolism, Inborn Errors; Biopterins; Carbidopa; Catecholamines; Dose-Response Relationship, Drug; Female; Humans; Infant; Levodopa; Neopterin; Neurotransmitter Agents; Pteridines; Pterins | 1984 |
Biopterin synthesis defects: problems in diagnosis.
Topics: Biopterins; Diet; Female; Humans; Infant, Newborn; Metabolism, Inborn Errors; Neopterin; Neurotransmitter Agents; Phenylalanine; Pteridines | 1984 |
The influence of some pterins on the circadian rhythmicity of hydroxyindole-O-methyl transferase in the pineal gland of 42-day old male Wistar rats.
Topics: 5-Hydroxytryptophan; Acetylserotonin O-Methyltransferase; Animals; Biopterins; Circadian Rhythm; Hydroxyindoleacetic Acid; Hydroxytryptophol; Male; Methylation; Methyltransferases; Neopterin; Pteridines; Pterins; Rats; Rats, Inbred Strains; Serotonin; Xanthopterin | 1980 |
The influence of some pteridines on pineal 5-methoxyindole synthesis in male Wistar rats periodically exposed to either white or green light.
Topics: 5-Methoxytryptamine; Animals; Biopterins; Hydroxyindoleacetic Acid; Indoles; Light; Male; Melanins; Neopterin; Pineal Gland; Pteridines; Pterins; Rats; Rats, Inbred Strains; Tryptophan | 1983 |
Pteridines as a new marker to detect human T cells activated by allogeneic or modified self major histocompatibility complex (MHC) determinants.
Topics: Adult; Biopterins; Cytomegalovirus Infections; Graft Rejection; HLA Antigens; Humans; Immunosuppressive Agents; Kidney Failure, Chronic; Kidney Transplantation; Lymphocyte Activation; Male; Middle Aged; Neopterin; Pteridines; T-Lymphocytes | 1983 |
Raised serum neopterin levels and imbalances of T-lymphocyte subsets in viral diseases, acquired immune deficiency and related lymphadenopathy syndromes.
Topics: Acquired Immunodeficiency Syndrome; Adult; Biopterins; Humans; Lymphatic Diseases; Neopterin; Pteridines; T-Lymphocytes; Virus Diseases | 1984 |
Neopterin as a new biochemical marker for diagnosis of allograft rejection. Experience based upon evaluation of 100 consecutive cases.
Topics: Biopterins; Cyclosporins; Graft Rejection; Humans; Immune Tolerance; Kidney Transplantation; Liver Transplantation; Neopterin; Pancreas Transplantation; Pteridines; Transplantation, Homologous | 1983 |
Polarization fluoroimmunoassay of biopterin and neopterin in human urine.
Topics: Animals; Biopterins; Fluorescence Polarization; Fluorescent Antibody Technique; Humans; Immune Sera; Neopterin; Pteridines; Rabbits; Radioimmunoassay | 1984 |
Formation of beta,gamma-methylene-7,8-dihydroneopterin 3'-triphosphate from beta,gamma-methyleneguanosine 5'-triphosphate by GTP cyclohydrolase I of Escherichia coli.
Topics: Aminohydrolases; Chemical Phenomena; Chemistry; Chromatography; Escherichia coli; GTP Cyclohydrolase; Guanosine Triphosphate; Neopterin; Pteridines; Spectrometry, Fluorescence; Substrate Specificity | 1984 |
Neopterin as a new biochemical marker in the clinical monitoring of bone marrow transplant recipients.
Topics: Biopterins; Bone Marrow Transplantation; Chromatography, High Pressure Liquid; Clinical Laboratory Techniques; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Neopterin; Pteridines | 1984 |
Enzymatic conversion of dihydroneopterin triphosphate to the pyrimidodiazepine intermediate involved in the biosynthesis of the drosopterins in Drosophila melanogaster.
Topics: Animals; Azepines; Chromatography, High Pressure Liquid; Drosophila melanogaster; Glutathione; Kinetics; Magnesium; Magnesium Chloride; Mercaptoethanol; Neopterin; Pteridines; Pterins | 1984 |
A defective enzyme in hyperphenylalaninaemia due to biopterin deficiency.
Topics: Adolescent; Adult; Alcohol Oxidoreductases; Biopterins; Child; Child, Preschool; Erythrocytes; Female; Humans; Infant; Infant, Newborn; Male; Middle Aged; Multienzyme Complexes; Neopterin; Phenylalanine; Pteridines | 1983 |
Intermediates in the enzymic synthesis of tetrahydrobiopterin in Drosophila melanogaster.
Topics: Animals; Biopterins; Biotransformation; Catalysis; Drosophila melanogaster; Edetic Acid; Magnesium; NADP; Neopterin; Pteridines; Pterins | 1984 |
Immune response-associated production of neopterin. Release from macrophages primarily under control of interferon-gamma.
Topics: Biopterins; Humans; Interferon-gamma; Lymphocyte Activation; Macrophage Activation; Macrophages; Monocytes; Neopterin; Pteridines; T-Lymphocytes | 1984 |
Lethal mutations induced in Drosophila melanogaster by direct or indirect action of pteridines.
Topics: Animals; Biopterins; Drosophila melanogaster; Genes, Lethal; Genes, Recessive; Lepidoptera; Mutagenicity Tests; Mutagens; Mutation; Neopterin; Pteridines; Tissue Extracts | 1984 |
Purification and properties of the enzymes from Drosophila melanogaster that catalyze the conversion of dihydroneopterin triphosphate to the pyrimidodiazepine precursor of the drosopterins.
Topics: Alcohol Oxidoreductases; Animals; Azepines; Chromatography, Gel; Chromatography, Ion Exchange; Drosophila melanogaster; Eye Color; Ketone Oxidoreductases; Mutation; Neopterin; Phosphorus-Oxygen Lyases; Pteridines; Pterins; Spectrophotometry | 1984 |
Combined tetrahydrobiopterin-phenylalanine loading test in the detection of partially defective biopterin synthesis.
Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Biopterins; Child; Child, Preschool; Electroencephalography; Female; Humans; Neopterin; Phenylalanine; Pteridines | 1984 |
Urinary neopterin is elevated in patients with malaria.
Topics: Adolescent; Adult; Biopterins; Child; Chromatography, High Pressure Liquid; Female; Humans; Malaria; Male; Middle Aged; Neopterin; Pteridines | 1984 |
Biopterin cofactor biosynthesis: GTP cyclohydrolase, neopterin and biopterin in tissues and body fluids of mammalian species.
Topics: Aminohydrolases; Animals; Biopterins; Cricetinae; Dogs; GTP Cyclohydrolase; Guinea Pigs; Macaca fascicularis; Mice; Neopterin; Pteridines; Rats; Tissue Distribution | 1984 |
Radioimmunoassay for neopterin in body fluids and tissues.
Topics: Animals; Biopterins; Chromatography, High Pressure Liquid; Cross Reactions; Humans; Liver; Neopterin; Pteridines; Radioimmunoassay; Rats; Spectrometry, Fluorescence | 1984 |
Urinary neopterin in the diagnosis and follow-up of neoplasia: a biochemical parameter to detect cell-mediated immune response.
Topics: Adolescent; Adult; Aged; Biopterins; Female; Follow-Up Studies; Genital Neoplasms, Female; Humans; Immunity, Cellular; Leukemia; Lymphoma; Male; Middle Aged; Neoplasms; Neopterin; Pteridines; Urologic Neoplasms | 1984 |
Neopterin as an index of immune response in patients with tuberculosis.
Topics: Adolescent; Adult; Aged; Biopterins; Chromatography, High Pressure Liquid; Female; Humans; Immunity, Cellular; Male; Middle Aged; Neopterin; Prognosis; Pteridines; Tuberculosis, Pulmonary | 1984 |
Urinary pteridines on patients suffering from cancer. A comment on the method and results of Rao and associates and of Trehan and associates.
Topics: Biopterins; Charcoal; Chromatography, High Pressure Liquid; Humans; Leukemia, Myeloid, Acute; Neopterin; Pteridines; Pterins; Spectrometry, Fluorescence | 1984 |
Urinary excretion of biopterin and neopterin in psychiatric disorders.
Topics: Adult; Biopterins; Bipolar Disorder; Depressive Disorder; Female; Humans; Male; Middle Aged; Neopterin; Pteridines; Schizophrenia | 1984 |
[Neopterin, a new biochemical marker for the detection of activated T lymphocytes].
Topics: Arthritis, Rheumatoid; Biopterins; Dermatitis, Contact; Graft Rejection; Histocytochemistry; Humans; Immunity, Cellular; Lymphocyte Activation; Neoplasms; Neopterin; Pteridines; T-Lymphocytes; Tuberculosis, Pulmonary; Virus Diseases | 1983 |
[Neopterin, a new biochemical marker for clinical assessment of cell-mediated immune response].
Topics: Adolescent; Adult; Aged; Biopterins; Female; Humans; Immune System Diseases; Immunity, Cellular; In Vitro Techniques; Male; Middle Aged; Neopterin; Pteridines; T-Lymphocytes | 1984 |
Elevated urinary neopterin levels in patients with the acquired immunodeficiency syndrome (AIDS). A preliminary report.
Topics: Acquired Immunodeficiency Syndrome; Biopterins; Chromatography, High Pressure Liquid; Humans; Lymphoproliferative Disorders; Neopterin; Pteridines; Reference Values | 1983 |
Tetrahydrobiopterin is synthesized by separate pathways from dihydroneopterin triphosphate and from sepiapterin in adrenal medulla preparations.
Topics: Adrenal Medulla; Animals; Biopterins; Cattle; Chemical Phenomena; Chemistry; Guanosine Triphosphate; Methotrexate; Neopterin; Pteridines; Pterins | 1983 |
Dihydrobiopterin biosynthesis deficiency.
Topics: Biopterins; Female; Humans; Infant; Infant, Newborn; Metabolism, Inborn Errors; Neopterin; Phenylalanine; Pteridines | 1983 |
Improved diagnosis of classical vs atypical phenylketonuria by liquid chromatography.
Topics: Biopterins; Chromatography, Liquid; Creatinine; Humans; Infant; Neopterin; Phenylketonurias; Pteridines; Statistics as Topic | 1984 |
Guanosine triphosphate cyclohydrolase activity in rat tissues.
Topics: Aminohydrolases; Animals; Brain; Chromatography, Gel; Formates; GTP Cyclohydrolase; Kidney; Liver; Male; Models, Chemical; Neopterin; Pteridines; Rats; Rats, Inbred Strains; Tissue Distribution | 1984 |
Urinary neopterin in the diagnosis of acquired immune deficiency syndrome.
Topics: Acquired Immunodeficiency Syndrome; Biopterins; Humans; Male; Neopterin; Pteridines | 1984 |
Current status of biopterin screening.
Topics: Biopterins; Chromatography, High Pressure Liquid; Humans; Infant; Infant, Newborn; Mass Screening; Neopterin; Phenylalanine; Phenylketonurias; Pteridines | 1984 |
GTP cyclohydrolase I deficiency, a new enzyme defect causing hyperphenylalaninemia with neopterin, biopterin, dopamine, and serotonin deficiencies and muscular hypotonia.
Topics: Adolescent; Aminohydrolases; Biopterins; Child; Child, Preschool; Dopamine; Female; GTP Cyclohydrolase; Humans; Infant; Liver; Metabolism, Inborn Errors; Muscle Hypotonia; Neopterin; Phenylalanine; Pteridines; Serotonin | 1984 |
Neopterin retards loss of serotonin N-acetyltransferase activity from cultured chick pineal glands.
Topics: Acetyltransferases; Animals; Arylamine N-Acetyltransferase; Biopterins; Cells, Cultured; Chickens; Circadian Rhythm; Darkness; Kinetics; Light; Neopterin; Photolysis; Pineal Gland; Pteridines | 1984 |
Tetrahydrobiopterin metabolism in the temporal lobe of patients dying with senile dementia of Alzheimer type.
Topics: Aged; Alzheimer Disease; Biopterins; Dihydropteridine Reductase; Humans; Kinetics; Neopterin; Pteridines; Temporal Lobe | 1984 |
Pterin metabolism in normal subjects and hyperphenylalaninaemic patients.
Topics: Adult; Alcohol Oxidoreductases; Biopterins; Child; Child, Preschool; Chromatography, High Pressure Liquid; Humans; Infant; NADH, NADPH Oxidoreductases; Neopterin; Phenylalanine; Phenylketonurias; Pteridines; Pterins; Xanthopterin | 1981 |
Synthesis of biopterin from dihydroneopterin triphosphate by rat tissues.
Topics: Animals; Biopterins; Chromatography, High Pressure Liquid; Iodine; Kidney; Liver; Neopterin; Oxidation-Reduction; Pineal Gland; Pteridines; Rats; Rats, Inbred Strains | 1983 |
Guanosine triphosphate cyclohydrolase I assay in human and rat liver using high-performance liquid chromatography of neopterin phosphates and guanine nucleotides.
Topics: Aminohydrolases; Animals; Biopterins; Chromatography, High Pressure Liquid; GTP Cyclohydrolase; Guanine Nucleotides; Humans; Liver; Neopterin; Pteridines; Rats; Rats, Inbred Strains; Spectrometry, Fluorescence | 1983 |
Determination of biopterin and other pterins in tissues and body fluids by high-performance liquid chromatography.
Topics: Biopterins; Body Fluids; Chromatography, High Pressure Liquid; Humans; Neopterin; Neuroblastoma; Pteridines; Pterins; Xanthopterin | 1983 |
Measurement of urinary neopterin in normal pregnant and non-pregnant women and in women with benign and malignant genital tract neoplasms.
Topics: Adolescent; Adult; Aged; Biopterins; Female; Genital Neoplasms, Female; Humans; Male; Middle Aged; Neopterin; Postpartum Period; Precancerous Conditions; Pregnancy; Pteridines; Reference Values; Uterine Cervical Neoplasms; Uterine Neoplasms | 1983 |
Significance of urinary neopterine in gynecological oncology: follow-up of patients with ovarian cancer.
Topics: Adult; Aged; Biopterins; Female; Follow-Up Studies; Humans; Middle Aged; Neopterin; Ovarian Neoplasms; Pteridines | 1983 |
Isolation and preparation of pterins from biological materials.
Topics: Animals; Anura; Biopterins; Chromatography, Ion Exchange; Neopterin; Oxidation-Reduction; Pteridines; Pterins; Rana catesbeiana; Skin | 1980 |
Determination of neopterine in human urine by reversed-phase high-performance liquid chromatography.
Topics: Adolescent; Adult; Age Factors; Aged; Biopterins; Child; Child, Preschool; Chromatography, High Pressure Liquid; Creatinine; Female; Humans; Male; Middle Aged; Neopterin; Pteridines; Reference Values; Sex Factors | 1982 |
Urinary neopterine in the assessment of lymphoid and myeloid neoplasia, and neopterine levels in haemolytic anaemia and benign monoclonal gammopathy.
Topics: Adolescent; Adult; Aged; Anemia, Hemolytic; Biopterins; Female; Humans; Hypergammaglobulinemia; Leukemia; Lymphoma; Male; Middle Aged; Multiple Myeloma; Neopterin; Pteridines | 1982 |
Urinary neopterine excretion in patient with genital cancer.
Topics: Adult; Aged; Biopterins; Female; Genital Neoplasms, Female; Humans; Male; Middle Aged; Neopterin; Pteridines; Reference Values; Sex Factors | 1982 |
Atypical phenylketonuria with defective biopterin metabolism. Monotherapy with tetrahydrobiopterin or sepiapterin, screening and study of biosynthesis in man.
Topics: Biopterins; Child, Preschool; Female; Humans; Neopterin; Phenylalanine; Phenylketonurias; Pteridines; Pterins; Serotonin | 1982 |
Use of tetrahydropterins in the treatment of hyperphenylalaninemia due to defective synthesis of tetrahydrobiopterin: evidence that peripherally administered tetrahydropterins enter the brain.
Topics: Biopterins; Brain; Child; Child, Preschool; Female; Humans; Male; Neopterin; Phenylalanine; Phenylketonurias; Pteridines; Pterins | 1982 |
Biosynthesis, nonenzymatic synthesis, and purification of the intermediate in synthesis of sepiapterin in Drosophila.
Topics: Drosophila; Hydrogen-Ion Concentration; Magnesium; NADP; Neopterin; Pteridines; Pterins | 1982 |
Developmental aspects of pteridine metabolism and relationships with phenylalanine metabolism.
Topics: Adolescent; Adult; Aging; Amniotic Fluid; Animals; Biopterins; Child; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Male; Neopterin; Phenylalanine; Phenylketonurias; Pregnancy; Pteridines; Rats; Rats, Inbred Strains | 1981 |
Urinary neopterine as marker for haematological neoplasias.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Biopterins; Chromatography, High Pressure Liquid; Clinical Laboratory Techniques; Female; Humans; Leukemia; Lymphoma; Male; Middle Aged; Neoplasm Staging; Neopterin; Pteridines; Reference Values | 1981 |
Altered urinary excretion of pteridines in neoplastic disease. Determination of biopterin, neopterin, xanthopterin, and pterin.
Topics: Biopterins; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Creatinine; Humans; Lymphoma; Neoplasms; Neopterin; Pteridines; Pterins; Xanthopterin | 1980 |
Neopterin and biopterin levels in patients with atypical forms of phenylketonuria.
Topics: Amino Acid Metabolism, Inborn Errors; Biopterins; Chromatography, High Pressure Liquid; Humans; Liver; Neopterin; Phenylalanine; Phenylketonurias; Pteridines | 1980 |
7,8 Dihydroneopterin inhibits low density lipoprotein oxidation in vitro. Evidence that this macrophage secreted pteridine is an anti-oxidant.
Topics: Adult; Amidines; Antioxidants; Biopterins; Copper; Dose-Response Relationship, Drug; Female; Humans; Linoleic Acid; Linoleic Acids; Lipoproteins, LDL; Macrophages; Male; Neopterin; Oxidation-Reduction; Pteridines; Pterins; Vitamin E | 1995 |
Atomic structure of GTP cyclohydrolase I.
Topics: Alcohol Oxidoreductases; Bacterial Proteins; Binding Sites; Biopterins; Catalysis; Crystallography, X-Ray; Escherichia coli; GTP Cyclohydrolase; Guanosine Triphosphate; Models, Molecular; Neopterin; Phosphorus-Oxygen Lyases; Protein Conformation; Pteridines | 1995 |
Detection of bacterial pyrogens on the basis of their effects on gamma interferon-mediated formation of neopterin or nitrite in cultured monocyte cell lines.
Topics: Animals; Bacterial Proteins; Biopterins; Cell Line; Endotoxins; Humans; Interferon-gamma; Lipopolysaccharides; Macrophages; Mice; Monocytes; Neopterin; Nitrites; Pteridines; Pyrogens; Salmonella typhimurium; Tumor Cells, Cultured | 1995 |
Pteridine biosynthesis in human endothelial cells. Impact on nitric oxide-mediated formation of cyclic GMP.
Topics: Amino Acid Oxidoreductases; Biopterins; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; GTP Cyclohydrolase; Humans; Hypoxanthines; Interferon-gamma; Lipopolysaccharides; Neopterin; Nitric Oxide; Nitric Oxide Synthase; Pteridines; Pterins; Tumor Necrosis Factor-alpha; Umbilical Veins | 1993 |
Effect of neopterin and 7,8-dihydroneopterin on tumor necrosis factor-alpha induced programmed cell death.
Topics: Acetylcysteine; Animals; Apoptosis; Biopterins; Cell Line; Drug Synergism; Hydrogen Peroxide; Neopterin; Oxidative Stress; Pteridines; Reactive Oxygen Species; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 1995 |
Enzymic characterization of Bacillus subtilis GTP cyclohydrolase I. Evidence for a chemical dephosphorylation of dihydroneopterin triphosphate.
Topics: Bacillus subtilis; Base Sequence; Binding, Competitive; Calcium; Folic Acid; Gene Expression; GTP Cyclohydrolase; Guanosine Triphosphate; Kinetics; Magnesium; Molecular Sequence Data; Neopterin; Operon; Phosphorylation; Plasmids; Potassium; Promoter Regions, Genetic; Pteridines; Recombinant Proteins; Uridine Triphosphate | 1995 |
Neopterin derivatives together with cyclic guanosine monophosphate induce c-fos gene expression.
Topics: 3T3 Cells; Animals; Base Sequence; Biopterins; Chloramphenicol O-Acetyltransferase; Cyclic GMP; Gene Expression Regulation, Neoplastic; Genes, fos; Humans; Mice; Molecular Sequence Data; Neopterin; Phorbol 12,13-Dibutyrate; Promoter Regions, Genetic; Protein Kinase C; Pteridines; Transcription, Genetic; Transcriptional Activation | 1994 |
Neopterin modulates toxicity mediated by reactive oxygen and chloride species.
Topics: Animals; Biopterins; Blood Bactericidal Activity; Chloramines; Escherichia coli; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hypochlorous Acid; In Vitro Techniques; Luminescent Measurements; Macrophages; Neopterin; Pteridines | 1993 |
Effect of pteridine derivatives on intracellular calcium concentration in human monocytic cells.
Topics: Biopterins; Calcium; Cell Line; Egtazic Acid; Humans; Lanthanum; Monocytes; Neopterin; Pteridines | 1993 |
Induction of inducible nitric oxide synthase expression by neopterin in vascular smooth muscle cells.
Topics: Animals; Antioxidants; Aorta; Base Sequence; Biopterins; Enzyme Induction; Interferon-gamma; Molecular Sequence Data; Muscle, Smooth, Vascular; Neopterin; Nitric Oxide Synthase; Nitrites; Pteridines; Rats; Rats, Inbred WKY; RNA, Messenger | 1995 |
Oxidative stress and apoptosis in HIV infection.
Topics: Apoptosis; Biopterins; CD4-Positive T-Lymphocytes; HIV Infections; HIV-1; Humans; Neopterin; Oxidative Stress; Pteridines; Reactive Oxygen Species | 1996 |
Effects of neopterin-derivatives on H2O2-induced luminol chemiluminescence: mechanistic aspects.
Topics: Biopterins; Chromatography, High Pressure Liquid; Edetic Acid; Ferric Compounds; Free Radical Scavengers; Histidine; Humans; Hydrogen Peroxide; Interferon-gamma; Iron Chelating Agents; Kinetics; Luminescent Measurements; Luminol; Macrophages; Monocytes; Neopterin; Oxygen; Pteridines; Singlet Oxygen | 1996 |
Role of 7,8-dihydroneopterin in T-cell apoptosis and HTLV-1 transcription in vitro.
Topics: Antioxidants; Apoptosis; Gene Products, tax; Human T-lymphotropic virus 1; Humans; Hydrogen Peroxide; Neopterin; Oxidation-Reduction; Pteridines; Repetitive Sequences, Nucleic Acid; T-Lymphocytes; Transfection; Tumor Cells, Cultured | 1996 |
Neopterin and 7,8-dihydroneopterin induce apoptosis in the rat alveolar epithelial cell line L2.
Topics: Animals; Apoptosis; Biopterins; Cell Line; Epithelial Cells; Epithelium; Female; Gene Expression; Interferon-gamma; Neopterin; Nitrates; Nitric Oxide Synthase; Nitrites; Pteridines; Pulmonary Alveoli; Rats; Rats, Inbred Lew; RNA, Messenger; Tumor Necrosis Factor-alpha | 1996 |
Dihydroneopterin triphosphate epimerase of Escherichia coli: purification, genetic cloning, and expression.
Topics: Amino Acid Sequence; Bacterial Proteins; Base Sequence; Cloning, Molecular; Escherichia coli; Escherichia coli Proteins; Genes, Bacterial; Molecular Sequence Data; Neopterin; Pteridines; Racemases and Epimerases; Restriction Mapping; Sequence Analysis, DNA; Sequence Homology, Amino Acid | 1997 |
trans-Activation of the HIV type 1 promoter by 7,8-dihydroneopterin in vitro.
Topics: Biopterins; Chloramphenicol O-Acetyltransferase; Gene Expression Regulation, Viral; HIV Core Protein p24; HIV Seropositivity; HIV-1; Humans; Jurkat Cells; Neopterin; NF-kappa B; Promoter Regions, Genetic; Pteridines; Recombinant Fusion Proteins; Transcription Factor AP-1; Transcriptional Activation; Tumor Necrosis Factor-alpha | 1997 |
7,8-Dihydroneopterin upregulates interferon-gamma promoter in T cells.
Topics: Antioxidants; Free Radicals; Gene Expression Regulation; Humans; Interferon-gamma; Jurkat Cells; Neopterin; Promoter Regions, Genetic; Pteridines; Superoxides; T-Lymphocytes; Up-Regulation | 1996 |
Pterin-6-aldehyde, an inhibitor of xanthine oxidase, has superoxide anion radical scavenging activity.
Topics: Biopterins; Chromatography, High Pressure Liquid; Free Radical Scavengers; Free Radicals; Humans; In Vitro Techniques; Magnetic Resonance Spectroscopy; Neopterin; Pteridines; Pterins; Superoxides; Xanthine Oxidase | 1997 |
Neopterin derivatives to activate NF-kappa B.
Topics: Biopterins; Humans; Macrophage Activation; Macrophages; Neopterin; NF-kappa B; Oxidation-Reduction; Oxidative Stress; Pteridines; Reactive Oxygen Species | 1997 |
Spin trapping study of antioxidant properties of neopterin and 7,8-dihydroneopterin.
Topics: Antioxidants; Biopterins; Electron Spin Resonance Spectroscopy; Kinetics; Neopterin; Oxidation-Reduction; Peroxides; Pteridines; Spin Labels; Superoxides | 1997 |
D-erythro-neopterin biosynthesis in the methanogenic archaea Methanococcus thermophila and Methanobacterium thermoautotrophicum deltaH.
Topics: Biopterins; Chromatography, Thin Layer; GTP Cyclohydrolase; Guanosine Triphosphate; Methanobacterium; Methanococcus; Neopterin; Pteridines | 1997 |
Neopterin derivatives modulate the nitration of tyrosine by peroxynitrite.
Topics: Hydrogen-Ion Concentration; Neopterin; Nitrates; Nitro Compounds; Pteridines; Pterins; Spectrophotometry; Tyrosine | 1998 |
Simultaneous determination of pteridines in multicomponent mixtures using derivative spectrophotometry and partial least-squares calibration.
Topics: Drug Combinations; Equipment Design; Least-Squares Analysis; Molecular Structure; Neopterin; Pteridines; Pterins; Spectrophotometry; Xanthopterin | 1998 |
7,8-Dihydroneopterin-induced apoptosis in Jurkat T lymphocytes: a comparison with anti-Fas- and hydrogen peroxide-mediated cell death.
Topics: Antibodies; Apoptosis; fas Receptor; Humans; Hydrogen Peroxide; Jurkat Cells; Neopterin; Phosphorylation; Pteridines; Tyrosine | 1998 |
Pteridines as inhibitors of xanthine oxidase: structural requirements.
Topics: Dose-Response Relationship, Drug; Isomerism; Kinetics; Neopterin; Pteridines; Structure-Activity Relationship; Xanthine Oxidase | 1999 |
Histidine 179 mutants of GTP cyclohydrolase I catalyze the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone triphosphate.
Topics: Catalytic Domain; Escherichia coli; GTP Cyclohydrolase; Guanosine Triphosphate; Histidine; Models, Chemical; Mutation; Neopterin; Nuclear Magnetic Resonance, Biomolecular; Pteridines; Pyrimidine Nucleotides | 1999 |
Effects of neopterin and 7,8-dihydroneopterin on hypoxia-induced renal erythropoietin production.
Topics: Animals; Antioxidants; Cell Hypoxia; Enzyme-Linked Immunosorbent Assay; Erythropoietin; Humans; Kidney; Male; Neopterin; Polymerase Chain Reaction; Pteridines; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1999 |
Formation of oxygen radicals in solutions of 7,8-dihydroneopterin.
Topics: Catalase; Chromatography, High Pressure Liquid; Edetic Acid; Hydroxyl Radical; Hydroxylation; Iron; Neopterin; Oxygen; Pteridines; Superoxide Dismutase; Superoxides | 1999 |
Neopterin derivatives modulate toxicity of reactive species on Escherichia coli.
Topics: Anti-Bacterial Agents; Chloramines; Disinfectants; Drug Interactions; Escherichia coli; Formaldehyde; Humans; Hydrogen Peroxide; Neopterin; Pteridines; Reactive Oxygen Species; Sodium Hypochlorite; Sodium Nitrite; Tosyl Compounds | 1999 |
Inhibition of haemolysis by the macrophage synthesized antioxidant, 7,8-dihydroneopterin.
Topics: Animals; Antioxidants; Erythrocyte Membrane; Hemolysis; In Vitro Techniques; Kinetics; Macrophages; Neopterin; Pteridines; Swine; Tyrosine | 2000 |
Oxidation of 7,8-dihydroneopterin by hypochlorous acid yields neopterin.
Topics: Chromatography, High Pressure Liquid; Hypochlorous Acid; Neopterin; Oxidation-Reduction; Pteridines; Radioimmunoassay | 2000 |
Ring opening is not rate-limiting in the GTP cyclohydrolase I reaction.
Topics: Aldose-Ketose Isomerases; Escherichia coli; Flow Injection Analysis; Formates; GTP Cyclohydrolase; Guanosine Triphosphate; Models, Chemical; Neopterin; Pteridines; Pyrimidine Nucleotides | 2001 |
Inflammation marker 7,8-dihydroneopterin induces apoptosis of neurons and glial cells: a potential contribution to neurodegenerative processes.
Topics: Acid Phosphatase; Antioxidants; Apoptosis; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Interferon-gamma; Neopterin; Neuroglia; Neurons; Pteridines | 2000 |
Protection of erythrocytes by the macrophage synthesized antioxidant 7,8 dihydroneopterin.
Topics: Amidines; Animals; Blood Proteins; Chromatography, High Pressure Liquid; Erythrocyte Membrane; Erythrocytes; Hemolysis; Humans; Hydrogen Peroxide; Hypochlorous Acid; Interferon-gamma; Lipid Peroxidation; Macrophages; Neopterin; Oxidation-Reduction; Pteridines; Swine; Tyrosine | 2001 |
Induction of apoptosis by 7,8-dihydroneopterin: involvement of radical formation.
Topics: Apoptosis; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Fas Ligand Protein; Humans; Hydroxyl Radical; Interferon-gamma; Jurkat Cells; Membrane Glycoproteins; Neopterin; Pteridines; Reactive Oxygen Species; Spin Labels; T-Lymphocytes | 2001 |
Inhibition of protein oxidation by the macrophage-synthesised antioxidant 7,8-dihydroneopterin.
Topics: Amidines; Animals; Antioxidants; Blood; Cattle; Free Radical Scavengers; Free Radicals; Hydroxyl Radical; Inflammation; Macrophages; Neopterin; Oxidants; Oxidation-Reduction; Peroxides; Proteins; Pteridines; Serum Albumin, Bovine | 2001 |
Protection of U937 cells from free radical damage by the macrophage synthesized antioxidant 7,8-dihydroneopterin.
Topics: Amidines; Antioxidants; Cell Survival; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Free Radicals; Humans; Hydrogen Peroxide; Hypochlorous Acid; Iron; Lipid Peroxidation; Macrophages; Neopterin; Pteridines; Thiobarbituric Acid Reactive Substances; U937 Cells | 2001 |
Influence of cytokines tumor necrosis factor-alpha and interferon-gamma on signaling cascades associated with apoptosis in rat PC12 cells.
Topics: Animals; Antioxidants; Apoptosis; Central Nervous System; Immunity, Cellular; Interferon-gamma; Macrophages; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinases; Neopterin; Neurodegenerative Diseases; Neurons; Oxidative Stress; PC12 Cells; Pteridines; Rats; Reactive Oxygen Species; Tumor Necrosis Factor-alpha | 2001 |
Reaction mechanism of GTP cyclohydrolase I: single turnover experiments using a kinetically competent reaction intermediate.
Topics: Catalysis; Escherichia coli; Formates; GTP Cyclohydrolase; Guanosine Triphosphate; Hydrolysis; Kinetics; Mutation; Neopterin; Pteridines; Pyrimidine Nucleotides; Schiff Bases; Spectrophotometry, Ultraviolet; Stereoisomerism | 2002 |
7,8-Dihydroneopterin induces apoptosis of Jurkat T-lymphocytes via a Bcl-2-sensitive pathway.
Topics: Antioxidants; Apoptosis; Enzyme Activation; Enzyme Inhibitors; Humans; Jurkat Cells; Mitogen-Activated Protein Kinases; Neopterin; Proto-Oncogene Proteins c-bcl-2; Pteridines; Serpins; Signal Transduction; Staurosporine; Viral Proteins | 2002 |
Plasma pteridine concentrations in patients with chronic renal failure.
Topics: Biomarkers; Biopterins; Humans; Kidney Failure, Chronic; Neopterin; Pteridines; Reference Values; Regression Analysis; Renal Dialysis | 2002 |
Generation of carbon monoxide and iron from hemeproteins in the presence of 7,8-dihydroneopterin.
Topics: Animals; Carbon Monoxide; Ferrous Compounds; Hemeproteins; Horses; Humans; Iron; Kinetics; Neopterin; Pteridines; Spectrum Analysis | 2002 |
Neopterin and 7,8-dihydroneopterin interfere with low density lipoprotein oxidation mediated by peroxynitrite and/or copper.
Topics: Copper; Drug Interactions; Electrophoretic Mobility Shift Assay; Humans; Lipoproteins, LDL; Macrophages; Neopterin; Oxidation-Reduction; Peroxynitrous Acid; Pteridines | 2002 |
Protein and thiol oxidation in cells exposed to peroxyl radicals is inhibited by the macrophage synthesised pterin 7,8-dihydroneopterin.
Topics: Amidines; Antioxidants; Cell Survival; Humans; Macrophages; Neopterin; Oxidants; Oxidation-Reduction; Peroxides; Pteridines; Sulfhydryl Compounds; U937 Cells | 2002 |
Biosynthesis of pteridines. Reaction mechanism of GTP cyclohydrolase I.
Topics: Amino Acid Sequence; Animals; Binding Sites; Catalysis; Crystallization; Crystallography, X-Ray; Escherichia coli; Formamides; Formates; GTP Cyclohydrolase; Guanosine Triphosphate; Hydrogen Bonding; Hydrolysis; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Neopterin; Protein Conformation; Pteridines; Stereoisomerism; Zinc | 2003 |
Induction of apoptosis in human blood T cells by 7,8-dihydroneopterin: the difference between healthy controls and patients with systemic lupus erythematosus.
Topics: Adult; Annexin A5; Antioxidants; Apoptosis; Cells, Cultured; Concanavalin A; Cytokines; Dose-Response Relationship, Drug; Female; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Neopterin; Phytohemagglutinins; Pteridines; T-Lymphocytes; Time Factors | 2003 |
A nudix enzyme removes pyrophosphate from dihydroneopterin triphosphate in the folate synthesis pathway of bacteria and plants.
Topics: Amino Acid Sequence; Diphosphates; Escherichia coli; Folic Acid; Kinetics; Lactococcus lactis; Magnesium; Manganese; Molecular Sequence Data; Neopterin; Nudix Hydrolases; Open Reading Frames; Phylogeny; Plants; Pteridines; Pyrophosphatases; Substrate Specificity | 2005 |
Evaluation of pteridine metabolism in battery workers chronically exposed to lead.
Topics: Adult; Air Pollutants, Occupational; Aminolevulinic Acid; Biomarkers; Biopterins; Creatinine; Dihydropteridine Reductase; Environmental Monitoring; Evaluation Studies as Topic; Humans; Lead; Male; Neopterin; Neuromuscular Junction Diseases; Occupational Exposure; Pteridines | 2006 |
Escherichia coli QueD is a 6-carboxy-5,6,7,8-tetrahydropterin synthase.
Topics: Carbon-Oxygen Lyases; Escherichia coli; Escherichia coli Proteins; Neopterin; Pteridines | 2009 |
Differences in pteridine urinary levels in patients with malignant and benign ovarian tumors in comparison with healthy individuals.
Topics: Adult; Aged; Biopterins; Chromatography, High Pressure Liquid; Female; Humans; Manganese Compounds; Middle Aged; Neopterin; Ovarian Neoplasms; Oxides; Pteridines | 2015 |
Urinary neopterin and biopterin indicate that inflammation has a role in autism spectrum disorder.
Topics: Autism Spectrum Disorder; Biomarkers; Biopterins; Cross-Sectional Studies; Humans; Inflammation; Neopterin; Prospective Studies; Pteridines | 2023 |