pteridines has been researched along with folic acid in 158 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 122 (77.22) | 18.7374 |
1990's | 11 (6.96) | 18.2507 |
2000's | 19 (12.03) | 29.6817 |
2010's | 5 (3.16) | 24.3611 |
2020's | 1 (0.63) | 2.80 |
Authors | Studies |
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Turner, AJ | 1 |
Bonner, JT; Hall, EM; Pan, P | 1 |
Dinya, Z; Hernádi, FJ; Papp, S; Tóth-Martinez, BL | 1 |
Fukushima, T | 1 |
Graham, DW; Morman, H; Rogers, EF; Tolman, RL; Zimmerman, M | 1 |
Murphy, M; Scott, JM | 1 |
Fujino, S; Ikeda, M; Iwai, K | 1 |
Piper, WN; Van Lier, BL | 1 |
Reed, B; Scott, J; Weir, D | 1 |
Brown, GM; Fan, CL; Krivi, GG | 1 |
Scott, JM; Weir, DG | 1 |
Blair, JA; Leeming, RJ; Melikian, V; O'Gorman, DJ | 1 |
Gasco, MR | 2 |
Courtney, G; McNulty, H; McPartlin, J; Scott, J; Weir, D | 1 |
Ku, WW; Piper, WN | 1 |
Alam, A; Shen, RS; Zhang, YX | 1 |
Morrison, JF; Stone, SR | 1 |
Howells, DW; Hyland, K; Smith, I | 1 |
Andondonskaja-Renz, B; Zeitler, HJ | 1 |
Banks, SD; Bigham, EC; Nichol, CA; Smith, GK | 1 |
Newell, PC; Tillinghast, HS | 1 |
Granger, DN; Hollwarth, ME; McCord, JM; Parks, DA | 1 |
Kusano, G; Okinaka, O; Stokstad, EL | 1 |
Krungkrai, J; Webster, HK; Yuthavong, Y | 1 |
Hyland, K; Kendall, B; Smith, I | 1 |
Webber, S; Whiteley, JM | 1 |
Barnes, J; Hunter, R | 1 |
Sirotnak, FM | 1 |
Baugh, CM; Nair, MG | 1 |
Fukushima, T; Shiota, T | 2 |
Cooper, BA; Lavoie, A | 1 |
Buehring, KU; Shin, YS; Stokstad, EL | 1 |
Brade, W; Propping, P | 2 |
Iwai, K; Okinaka, O | 4 |
Brown, GM; Burg, AW | 1 |
Brown, GM; Richey, DP | 2 |
Baugh, CM; Dillard, R; Jackson, R; Shiota, T | 1 |
Summers, MR | 1 |
Brown, GM | 1 |
Hotchkiss, RD; Ortiz, PJ | 1 |
Zakrzewski, S | 1 |
Hecker, E; Marks, F | 1 |
Burchall, J | 1 |
Burchall, JJ; Hitchings, GH | 1 |
Gutteridge, WE; Jaffe, JJ; McCormack, JJ | 1 |
Butt, VS; Vaughan, PF | 1 |
Ortiz, PJ | 1 |
Dann, JG; Harding, NG; Newbold, PC; Whiteley, JM | 1 |
Godoy, GA; Soldo, AT | 1 |
Seifert, RM | 1 |
Bacher, A; Rappold, H | 2 |
Davies, J; Watkins, JC | 1 |
Doukas, PH; Miller, GH; Seydel, JK | 1 |
Kawai, M; Scrimgeour, KG | 1 |
Dunlap, RB; Ellis, PD; Lyon, JA | 1 |
Thijssen, HH | 1 |
Roberts, PJ | 1 |
Brown, GM; Jones, TH | 1 |
Luckner, M | 1 |
Weissbach, H; Whitfield, CD | 1 |
Brown, GM; Wolf, WA | 1 |
Dickerman, HW; Smith, BC | 1 |
Crusberg, TC; Kisliuk, RL; Leary, R | 1 |
Schlee, D; Zurnieden, K | 1 |
Kozloff, LM; Lute, M | 1 |
Desai, RB; Mankodi, BS; Rege, DV | 1 |
Kirschfeld, S; Lochmann, ER; Wacker, A | 1 |
Iwai, K; Okinaka, O; Suzuki, N | 1 |
Genther, CS; Kisliuk, RL; Roszmann, JH; Smith, CC | 1 |
Blair, JA; Dransfield, E | 1 |
Herken, H | 1 |
Huennekens, FM; Scrimgeour, KG; Vitols, KS; Vonderschmitt, DJ | 1 |
Beavon, JR; Blair, JA | 1 |
Baugh, CM | 1 |
Grzelakowska-Sztabert, B | 1 |
Baker, H; Frank, O; Hutner, SH | 1 |
Rembold, H; Vaubel, A | 1 |
Cihar, R; Slavík, K; Sonka, J; Straková, M | 1 |
Dewey, VC; Kidder, GW | 2 |
Odintsova, EN; Zhukova, SV | 1 |
Dewey, VC; Kidder, GW; Rembold, H | 1 |
utterworth, CE | 1 |
Drais, J; Huennekens, FM; Kirchner, J; Whiteley, JM | 1 |
Goldman, P; Levy, CC | 1 |
Trager, W | 1 |
Drais, JH; Huennekens, FM; Whiteley, JM | 1 |
Baker, BR; Ho, BT | 1 |
Baugh, CM; Krumdieck, CL; Shaw, E | 1 |
Jencks, WP; Kallen, RG | 1 |
Kawai, F; Mitsuda, H; Suzuki, Y; Tadera, K | 2 |
Palumbo, MP; Shiota, T; Tsai, L | 1 |
Neely, WB | 1 |
Huennekens, FM; Whiteley, JM | 1 |
Bublitz, C; Priest, RE | 1 |
Barr, FE | 1 |
Dhondt, JL | 1 |
Devreotes, PN | 1 |
Ferone, R; Spector, T | 1 |
Fleary, M; Lewis, AS; McCalla, C; Murphy, L; Purcell, S | 1 |
De Wit, RJ; Konijn, TM; van der Velden, RJ | 1 |
Cremer-Bartels, G; Ebels, I | 1 |
Benkovic, SJ | 1 |
Carey, PR; King, RW; Ozaki, Y | 1 |
De Saizieu, A; van Loon, AP; Vankan, P | 1 |
Adair, WL; Irby, RB | 1 |
Birdsall, B; Chau, DD; Cheung, HT; Feeney, J; Frenkiel, TA | 1 |
Beverley, SM; Hardy, LW; Nare, B | 1 |
Carl, GF; Hudson, FZ; McGuire, BS | 1 |
Rajagopalan, KV | 1 |
Haimeur, A; Kündig, C; Légaré, D; Ouellette, M; Papadopoulou, B | 1 |
Bagley, PJ; Selhub, J | 1 |
Ahmad, I; Akhtar, MJ; Khan, MA | 1 |
McPartlin, J; Quinlivan, EP; Scott, J; Weir, DG | 1 |
Beverley, SM; Cunningham, ML | 1 |
Chenon, K; De Lorenzi, E; Hall, AJ; Quaglia, M; Sellergren, B | 1 |
Rifkin, JL | 1 |
Gregory, JF; Hanson, AD | 1 |
Enzinger, C; Fuchs, D; Laich, A; Widner, B; Wirleitner, B | 1 |
Freisleben, A; Rychlik, M; Schieberle, P | 1 |
Braun, AM; Capparelli, AL; Lorente, C; Oliveros, E; Pokhrel, MR; Thomas, AH | 1 |
TOTTER, JR | 1 |
COLLIER, HO; GRIMSHAW, JJ; HUSKINSON, PL | 1 |
ANDERSON, ML; HERMAN, EC; WRIGHT, BE | 1 |
KAUFMAN, S | 1 |
KNAPP, A; MULLER, R | 1 |
KENNEDY, EP; LINDBERG, M; TIETZ, A | 1 |
BROWN, GM; REYNOLDS, JJ | 1 |
BONI, P; COLARUSSO, A; DE LERMA, B | 1 |
Basset, GJ; Díaz de la Garza, R; Gregory, JF; Hanson, AD; Klaus, SM; Quinlivan, EP | 1 |
Gregory, JF; Hanson, AD; Hugenholtz, J; Klaus, SM; Sybesma, W; Wegkamp, A | 1 |
Hirakawa, K | 1 |
Noszál, B; Szakács, Z | 1 |
De Lorenzi, E; Hall, AJ; Manesiotis, P; Quaglia, M; Sellergren, B | 1 |
Kolho, KL; Savilahti, E; Tikkakoski, S | 1 |
Ames, BN; Ayling, JE; Bailey, SW; Nozawa, M; Offer, T; Sabens, EA | 1 |
Díaz de la Garza, RI; Gregory, JF; Hanson, AD | 1 |
Allecca, S; Cavazzuti, A; Corona, P; Costi, MP; Ferrari, S; Gamarro, F; Gibellini, F; Hunter, WN; Loriga, M; McLuskey, K; Paglietti, G; Piras, S; Tulloch, L | 1 |
Beverley, SM; Garraway, LA; Nare, B; Vickers, TJ | 1 |
Beverley, SM; Vickers, TJ | 1 |
Dyer, RB; Li, G; Magana, D | 1 |
Duff, MR; Grubbs, J; Howell, EE; Serpersu, E | 1 |
Grigalavicius, M; Juraleviciute, M; Juzeniene, A; Ma, LW | 1 |
Engin, A; Engin, AB | 1 |
Agili, F; El-Kalyoubi, S | 1 |
17 review(s) available for pteridines and folic acid
Article | Year |
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Commentary: The roles of folate and pteridine derivatives in neurotransmitter metabolism.
Topics: Animals; Biogenic Amines; Brain; Folic Acid; Glycine; Humans; In Vitro Techniques; Mental Disorders; Methylation; Neurotransmitter Agents; Pteridines; Pterins; Subcellular Fractions | 1977 |
Pterin-6-aldehyde production from folic acid by malignant tissues.
Topics: Erythrocytes; Folic Acid; Humans; Neoplasms; Pteridines; Pterins | 1977 |
Lengths of poly-gamma-glutamyl chains in natural folates.
Topics: Animals; Chemical Phenomena; Chemistry; Folic Acid; Glutamates; Lacticaseibacillus casei; Liver; Male; Oligopeptides; Oxidation-Reduction; Peptide Fragments; Peptides; Pteridines; Rats; Streptococcus | 1975 |
Folate composition, synthesis and function in natural materials.
Topics: Animals; Bacteria; Bacteriophages; Bile; Brain; Cattle; Chickens; Folic Acid; Food; Glutamates; Haplorhini; Horses; Humans; Kidney; Liver; Mice; Plants; Pteridines; Rats | 1976 |
Pteridines and mono-amines: relevance to neurological damage.
Topics: Amines; Biopterins; Folic Acid; Humans; Nervous System; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Pteridines | 1986 |
The biosynthesis of pteridines.
Topics: Aminobenzoates; Aminohydrolases; Escherichia coli; Folic Acid; Fructose-Bisphosphate Aldolase; Glutamates; Guanine Nucleotides; Guanosine Triphosphate; Isomerases; Kinetics; Phosphotransferases; Pteridines; Pterins; Spectrophotometry, Ultraviolet; Sulfonamides; Transferases | 1971 |
Inhibition of folate biosynthesis and function as a basis for chemotherapy.
Topics: Aminobenzoates; Animals; Binding Sites; Biological Transport; Drug Resistance, Microbial; Drug Synergism; Escherichia coli; Folic Acid; Folic Acid Antagonists; Glutamates; Guinea Pigs; Humans; Lactobacillus; Leucovorin; Methotrexate; NAD; NADP; Pteridines; Pyrimidines; Rabbits; Rats; Sulfonamides | 1965 |
[On new studies of the biosynthesis of N-heterocyclic compounds. 5. Formation and decomposition of substances with purine, pteridine, and benzopteridine ring systems].
Topics: Allantoin; Caffeine; Folic Acid; Heterocyclic Compounds; Methylation; Oxidation-Reduction; Pteridines; Purines; Pyrimidines; Theobromine | 1966 |
[Biochemistry and physiology of the flavinogenesis in microorganisms].
Topics: Adenine; Bacteria; Biotransformation; Catalysis; Chemical Phenomena; Chemistry; Coenzymes; Enzyme Activation; Enzyme Repression; Flavonoids; Folic Acid; Fungi; Glycosides; Guanine Nucleotides; Lactates; Phosphates; Pteridines; Purines; Pyrimidines; Riboflavin; Ribose; RNA; Saccharomyces; Uracil; Xanthine Oxidase; Xanthines | 1970 |
[The pathways of biosynthesis of pteridines and tetrahydrofolate].
Topics: Folic Acid; Pteridines | 1967 |
Tetrahydrobiopterin deficiencies: preliminary analysis from an international survey.
Topics: Adjuvants, Pharmaceutic; Alcohol Oxidoreductases; Amino Acid Metabolism, Inborn Errors; Biopterins; Female; Folic Acid; GTP Cyclohydrolase; Humans; Infant; Infant, Newborn; Male; Neurotransmitter Agents; Phenylalanine; Phenylketonurias; Pteridines | 1984 |
On the mechanism of action of folate- and biopterin-requiring enzymes.
Topics: Animals; Bacteria; Biopterins; Folic Acid; Formaldehyde; Formates; Glycine Hydroxymethyltransferase; Leukemia L1210; Liver; Methylenetetrahydrofolate Dehydrogenase (NADP); Mice; Mixed Function Oxygenases; Molecular Conformation; Oxidation-Reduction; Pteridines; Tetrahydrofolate Dehydrogenase | 1980 |
Biosynthesis and processing of the molybdenum cofactors.
Topics: Biopterins; Coenzymes; Escherichia coli; Folic Acid; Metalloproteins; Molecular Structure; Molybdenum; Molybdenum Cofactors; Pteridines; Riboflavin; Sulfurtransferases | 1997 |
Synthesis and turnover of folates in plants.
Topics: 4-Aminobenzoic Acid; Arabidopsis; Biological Transport; Carbon-Nitrogen Ligases; Enzymes; Folic Acid; Glutamic Acid; GTP Cyclohydrolase; Plants; Pteridines; Tetrahydrofolates; Transaminases | 2002 |
Hyperhomocysteinemia, pteridines and oxidative stress.
Topics: Animals; Folic Acid; Homocysteine; Humans; Immunity; Oxidative Stress; Pteridines; Risk Factors; Vascular Diseases | 2002 |
Folate metabolic pathways in Leishmania.
Topics: Amino Acid Oxidoreductases; Animals; Carrier Proteins; Folic Acid; Host-Parasite Interactions; Iron-Sulfur Proteins; Leishmania; Metabolic Networks and Pathways; Methionine; Multienzyme Complexes; Pteridines; Purines; Tetrahydrofolate Dehydrogenase; Tetrahydrofolates; Thymidylate Synthase; Transferases | 2011 |
The Interactions Between Kynurenine, Folate, Methionine and Pteridine Pathways in Obesity.
Topics: Animals; Folic Acid; Humans; Inflammation; Kynurenine; Methionine; Obesity; Pteridines; Signal Transduction | 2017 |
141 other study(ies) available for pteridines and folic acid
Article | Year |
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Determination of the active portion of the folic acid molecule in cellular slime mold chemotaxis.
Topics: Agar; Aminobenzoates; Biological Assay; Cell-Free System; Cellophane; Chemical Phenomena; Chemistry; Chemotaxis; Chromatography, Thin Layer; Cyclic AMP; Drug Synergism; Folic Acid; Glutamates; Myxomycetes; Pteridines; Pyrazines; Pyrimidines; Species Specificity | 1975 |
New vistas for P-aminobenzoate participation in the biosynthesis of dihydro folate: a tentative model of the tetrahydro folate multienzyme complex.
Topics: Adenylate Kinase; Aminobenzoates; Binding Sites; Escherichia coli; Folic Acid; Kinetics; Multienzyme Complexes; Phosphotransferases; Protein Binding; Protein Conformation; Pteridines; Tetrahydrofolate Dehydrogenase; Tetrahydrofolates | 1975 |
[Biosynthesis of folic acid and biopterin (author's transl)].
Topics: Adenosine Monophosphate; Animals; Biological Assay; Biopterins; Cyclic GMP; Folic Acid; Guanosine Triphosphate; Liver; Pteridines; Pterins; Purines; Rats; RNA; Trypanosoma | 1975 |
Inhibitors of folate biosynthesis. 1. Inhibition of dihydroneopterin aldolase by pteridine derivatives.
Topics: Aldehyde-Lyases; Escherichia coli; Folic Acid; Pteridines | 1977 |
The turnover catabolism and excretion of folate administered at physiological concentrations in the rat.
Topics: Animals; Female; Folic Acid; Glutamates; Male; Pteridines; Rats | 1979 |
Nutritional requirements for folate compounds and some enzyme activities involved in the folate biosynthesis.
Topics: Agaricales; Animals; Bacteria; Chickens; Dihydropteroate Synthase; Folic Acid; Fungi; Glutamates; Liver; Nutritional Requirements; Peptide Synthases; Pteridines; Pterins; Rats; Species Specificity; Transferases | 1977 |
Pteridine regulation of inhibition of hepatic uroporphyrinogen L synthetase activity by lead chloride.
Topics: Ammonia-Lyases; Animals; Binding, Competitive; Cytosol; Folic Acid; gamma-Glutamyl Hydrolase; Hydroxymethylbilane Synthase; In Vitro Techniques; Lead; Liver; Porphobilinogen Synthase; Protein Binding; Proteins; Pteridines; Rats | 1977 |
The occurrence of folate-derived pteridines in rat liver.
Topics: Animals; Chromatography, Ion Exchange; Folic Acid; Liver; Male; Pteridines; Rats | 1978 |
The conversion of dihydroneopterin triphosphate to sepiapterin by an enzyme system from Drosophila melanogaster.
Topics: Animals; Drosophila melanogaster; Folic Acid; Guanosine Triphosphate; Pteridines; Spectrophotometry; Spectrophotometry, Ultraviolet | 1975 |
Biopterin derivatives in human body fluids and tissues.
Topics: Adolescent; Adult; Biological Assay; Biopterins; Body Fluids; Brain Chemistry; Chemical Phenomena; Chemistry; Child; Chromatography, DEAE-Cellulose; Culture Media; Eukaryota; Female; Folic Acid; Humans; Leukemia; Liver; Male; Methotrexate; Middle Aged; Milk, Human; Psoriasis; Pteridines | 1976 |
[Complexes of pteridines with phenothiazine and phenoxazine derivatives].
Topics: Folic Acid; Oxazines; Phenothiazines; Pteridines | 1976 |
[Charge-transfer complexes of hematoporphyrin with pteridine derivatives].
Topics: Buffers; Folic Acid; Hematoporphyrins; Leucovorin; Methotrexate; Pteridines; Solutions | 1976 |
The quantitative analysis of endogenous folate catabolites in human urine.
Topics: 4-Aminobenzoic Acid; Chromatography, High Pressure Liquid; Folic Acid; Glutamates; Humans; para-Aminobenzoates; Pteridines; Radioisotope Dilution Technique; Tritium | 1992 |
Pteridine modulation of lead inhibition of uroporphyrinogen synthesis in erythroid precursor cells.
Topics: Animals; Cell Line; Dialysis; Folic Acid; Hematopoietic Stem Cells; Heme; Lead; Leukemia, Erythroblastic, Acute; Mice; Porphyrinogens; Pteridines; Uroporphyrinogens | 1990 |
Inhibition of GTP cyclohydrolase I by pterins.
Topics: Aminohydrolases; Animals; Biopterins; Folic Acid; GTP Cyclohydrolase; Kinetics; Liver; Neopterin; Oxidation-Reduction; Pteridines; Pterins; Rats; Xanthopterin | 1988 |
Mechanism of inhibition of dihydrofolate reductases from bacterial and vertebrate sources by various classes of folate analogues.
Topics: Animals; Binding, Competitive; Chickens; Escherichia coli; Folic Acid; Folic Acid Antagonists; Leucovorin; Liver; Methotrexate; NADP; Pteridines; Pyrimethamine; Tetrahydrofolate Dehydrogenase; Triazines; Trimethoprim | 1986 |
Evaluation of pteridines in patients with different tumors.
Topics: Adult; Aged; Erythrocytes; Folic Acid; Humans; Leukocytes; Middle Aged; Neoplasms; Pteridines | 1987 |
On the substrate specificity of bovine liver dihydrofolate reductase: new unconjugated dihydropterin substrates.
Topics: Animals; Biopterins; Cattle; Folic Acid; Kinetics; Liver; Pteridines; Pterins; Substrate Specificity; Tetrahydrofolate Dehydrogenase | 1987 |
Chemotaxis towards pteridines during development of Dictyostelium.
Topics: Actins; Chemical Phenomena; Chemistry; Chemotaxis; Dictyostelium; Folic Acid; Pteridines; Pterins; Time Factors; Xanthopterin | 1987 |
Xanthine oxidase inhibitors attenuate ischemia-induced vascular permeability changes in the cat intestine.
Topics: Animals; Blood Proteins; Capillary Permeability; Cats; Folic Acid; Free Radicals; Ileum; Ischemia; Lymph; Pteridines; Pterins; Time Factors; Xanthine Oxidase | 1986 |
Experiments on the biological activities of various fractions of the folic acid antagonist "X-methyl" folic acid.
Topics: Animals; Biological Assay; Folic Acid; Folic Acid Antagonists; Histidine; Liver; Oxidation-Reduction; Pteridines; Rats | 1986 |
Guanosine triphosphate cyclohydrolase in Plasmodium falciparum and other Plasmodium species.
Topics: Aminohydrolases; Animals; Chromatography, High Pressure Liquid; Erythrocytes; Folic Acid; Formates; GTP Cyclohydrolase; Kinetics; Neopterin; Plasmodium; Plasmodium berghei; Plasmodium falciparum; Pteridines | 1985 |
Clinical role of pteridine therapy in tetrahydrobiopterin deficiency.
Topics: Amino Acid Metabolism, Inborn Errors; Biogenic Amines; Biopterins; Brain; Folic Acid; Folic Acid Deficiency; Humans; Infant; Phenylalanine; Phenylketonurias; Pteridines | 1985 |
Comparative activity of rat liver dihydrofolate reductase with 7,8-dihydrofolate and other 7,8-dihydropteridines.
Topics: Animals; Enzyme Activation; Folic Acid; Folic Acid Antagonists; Hydrogen-Ion Concentration; Hydroxymercuribenzoates; Kinetics; Liver; Methotrexate; Osmolar Concentration; Pteridines; Rats; Substrate Specificity; Tetrahydrofolate Dehydrogenase; Urea | 1985 |
Toxicity of folic acid.
Topics: Amines; Brain; Folic Acid; Humans; Pteridines | 1971 |
Two different effects of mutation on the binding of folate antagonists by a microbial dihydrofolate reductase.
Topics: Amines; Amino Acids; Aminopterin; Binding Sites; Cell-Free System; Folic Acid; Folic Acid Antagonists; Genes; Hydrogen-Ion Concentration; Kinetics; Methotrexate; Mutation; NADP; Pteridines; Pyrimethamine; Pyrimidines; Species Specificity; Streptococcus pneumoniae; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Trimethoprim | 1973 |
Synthesis and biological evaluation of isofolic acid.
Topics: Enterococcus faecalis; Folic Acid; Folic Acid Antagonists; Isomerism; Lacticaseibacillus casei; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Pteridines; Structure-Activity Relationship; Thymidine | 1974 |
Biosynthesis of biopterin by Chinese hamster ovary (CHO K1) cell culture.
Topics: Animals; Anura; Biological Assay; Carbon Radioisotopes; Cell Line; Chromatography, Gel; Chromatography, Ion Exchange; Cricetinae; Culture Media; Drosophila melanogaster; Eukaryota; Female; Folic Acid; Guanine; Guanine Nucleotides; Guanosine; Mice; Models, Chemical; Neuroblastoma; Ovary; Pteridines; Pterins; Purine Nucleotides; RNA; Structure-Activity Relationship | 1974 |
Rapid transfer of folic acid from blood to bile in man, and its conversion into folate coenzymes and into a pteroylglutamate with little biological activity.
Topics: Adult; Aged; Aminobenzoates; Animals; Bile; Biological Assay; Biological Transport; Coenzymes; Dogs; Enterococcus faecalis; Folic Acid; Humans; Iodine Radioisotopes; Lacticaseibacillus casei; Liver; Middle Aged; Pediococcus; Pteridines; Rose Bengal; Tetrahydrofolates; Tritium; Ultrafiltration | 1974 |
The metabolism of methotrexate in Lactobacillus casei and rat liver and the influence of methotrexate on metabolism of folic acid.
Topics: Animals; Benzoates; Biological Assay; Carboxypeptidases; Chromatography, DEAE-Cellulose; Chromatography, Gel; Enterococcus faecalis; Folic Acid; Glutamates; Kidney; Lacticaseibacillus casei; Liver; Male; Methotrexate; Oxidation-Reduction; Pteridines; Rats; Swine; Tetrahydrofolates; Tritium | 1974 |
[Regeneration of the kidney after tubular damage by pteridine derivatives].
Topics: Animals; DNA; Folic Acid; Glycosuria; Kidney Tubules; Pteridines; Pyrimidines; Rats; Regeneration; Ribosomes; RNA; Xanthopterin | 1969 |
The biosynthesis of folic acid compounds in plants. IV. Purification and properties of the dihydropteroate-synthesizing enzyme from pea seedlings.
Topics: Adenosine Triphosphatases; Aminobenzoates; Chromatography, DEAE-Cellulose; Escherichia coli; Folic Acid; Hydrogen-Ion Concentration; Ligases; Magnesium; Plants; Pteridines; Seeds; Spectrophotometry; Sulfonamides; Ultracentrifugation; Ultraviolet Rays; Vegetables | 1970 |
The biosynthesis of folic acid compounds in plants. V. Reaction mechanism of the dihydropteroate-synthesizing enzyme from pea seedlings.
Topics: Adenosine Triphosphatases; Aminobenzoates; Chromatography, Gel; Chromatography, Paper; Folic Acid; Ligases; Magnesium; Phosphates; Phosphorus Isotopes; Plants; Pteridines; Seeds; Vegetables | 1970 |
The biosynthesis of folic acid. 8. Purification and properties of the enzyme that catalyzes the production of formate from carbon atom 8 of guanosine triphosphate.
Topics: Amidohydrolases; Arsenic; Carbon Isotopes; Chromatography, Gel; Chromatography, Ion Exchange; Escherichia coli; Folic Acid; Formates; Guanine Nucleotides; Kinetics; Molecular Weight; Phosphates; Phosphoric Monoester Hydrolases; Phosphorus Isotopes; Pteridines; Spectrum Analysis; Ultraviolet Rays | 1968 |
The biosynthesis of folic acid. IX. Purification and properties of the enzymes required for the formation of dihydropteroic acid.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Aminobenzoates; Autoradiography; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Diphosphates; Electrophoresis; Escherichia coli; Folic Acid; Hot Temperature; Kinetics; Ligases; Magnesium; Molecular Weight; Phosphorus Isotopes; Phosphotransferases; Pteridines | 1969 |
The enzymatic synthesis of hydroxymethyldihydropteridine pyrophosphate and dihydrofolate.
Topics: Adenosine Triphosphate; Aminobenzoates; Biological Assay; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography, DEAE-Cellulose; Dialysis; Folic Acid; Glutamates; Kinetics; Lactobacillus; Ligases; Methods; Phosphoric Acids; Phosphorus Isotopes; Phosphotransferases; Pteridines; Quaternary Ammonium Compounds; Spectrophotometry; Ultraviolet Rays | 1969 |
Reaction of N-bromosuccinimide with reduced ring systems. Apparent protection of glutamate dehydrogenase by reduced nicotinamide-adenine dinucleotide.
Topics: Bromine; Chemical Phenomena; Chemistry; Folic Acid; Glutamate Dehydrogenase; NAD; Oxidation-Reduction; Pteridines; Pyrrolidinones; Spectrophotometry; Succinimides; Ultraviolet Rays | 1972 |
The enzymatic synthesis of dihydrofolate and dihydropteroate in cell-free preparations from wild-type and sulfonamide-resistant pneumococcus.
Topics: Adenosine Triphosphate; Aminobenzoates; Biological Assay; Drug Resistance, Microbial; Enterococcus faecalis; Folic Acid; In Vitro Techniques; Magnesium; Molecular Biology; Mutation; Pteridines; Pterins; Streptococcus pneumoniae; Sulfanilamides | 1966 |
On the mechanism of chemical and enzymatic reduction of folate and dihydrofolate.
Topics: Chemical Phenomena; Chemistry; Deuterium; Folic Acid; NADP; Pteridines; Tetrahydrofolate Dehydrogenase; Tritium | 1966 |
[On the metabolism and mechanism of action of estrogens. 8. The biogenesis and metabolism of 2-hydroxyestrone in relation to the formation of protein-bound and water soluble estrone metabolites and to NADPH oxidation in rat liver microsomes].
Topics: Aminopterin; Animals; Carbon Isotopes; Cysteine; Estrone; Female; Folic Acid; Glutathione; Humans; Kinetics; Liver; Male; Microsomes; NADP; Oxidation-Reduction; Phenylalanine; Phosphates; Protein Binding; Pteridines; Rats; Steroids | 1966 |
Protection of microbial dihydrofolate reductase against inactivation by pronase.
Topics: Amines; Benzoates; Calcium; Chromatography; Endopeptidases; Escherichia coli; Folic Acid; Folic Acid Antagonists; Formates; Glutamates; Heterocyclic Compounds; Kinetics; Leucovorin; NAD; NADP; Protein Binding; Pteridines | 1968 |
Presence and properties of dihydrofolate reductases within the genus Crithidia.
Topics: Animals; Folic Acid; Folic Acid Antagonists; Hydrogen-Ion Concentration; Kinetics; Methotrexate; NADP; Pteridines; Pyrimethamine; Pyrimidines; Tetrahydrofolate Dehydrogenase; Trypanosoma | 1969 |
The hydroxylation of p-coumaric acid by an enzyme from leaves of spinach beet (Beta vulgaris L.).
Topics: Ascorbic Acid; Catechol Oxidase; Coumarins; Folic Acid; Mixed Function Oxygenases; NAD; NADP; Plants; Pteridines | 1969 |
Dihydrofolate and dihydropteroate synthesis by partially purified enzynes from wild-type and sulfonamide-resistant pneumonococcus.
Topics: Aminobenzoates; Benzoates; Binding Sites; Biological Assay; Catalase; Centrifugation, Density Gradient; Chemical Precipitation; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Drug Resistance, Microbial; Enterococcus faecalis; Enzymes; Folic Acid; Glutamates; Kinetics; Magnesium; Manganese; Methods; Molecular Weight; Phosphoric Acids; Pteridines; Quaternary Ammonium Compounds; Species Specificity; Streptococcus pneumoniae; Sulfanilamides | 1970 |
Single-step purification of dihydrofolate reductases on pteridine matrices.
Topics: Chromatography, Affinity; Folic Acid; Methods; Molecular Weight; NADP; Pteridines; Tetrahydrofolate Dehydrogenase | 1972 |
A requirement for an unconjugated pteridine for the growth of Paramecium aurelia.
Topics: Chromatography, Gel; Culture Media; Darkness; Folic Acid; Light; Paramecium; Pteridines; Spectrometry, Fluorescence; Thymidine | 1974 |
An approach to the chemical analysis of folic acid: gas chromatography of a degradation product from synthetic folic acid samples.
Topics: Aminobenzoates; Chemical Phenomena; Chemistry; Chromatography, Gas; Evaluation Studies as Topic; Folic Acid; Methods; Pteridines | 1974 |
Bacterial degradation of folic acid.
Topics: Amidohydrolases; Aminohydrolases; Cell-Free System; Chemical Phenomena; Chemistry; Chromatography, Thin Layer; Flagella; Folic Acid; Mass Spectrometry; Microscopy, Electron; Pseudomonas; Pteridines; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet | 1974 |
Facilitatory and direct excitatory effects of folate and folinate on single neurones of cat cerebral cortex.
Topics: Acetylcholine; Aminobutyrates; Animals; Cats; Cerebral Cortex; Folic Acid; Glutamates; Iontophoresis; Leucovorin; Neurons; Pteridines | 1973 |
Sulfonamide structure-activity relationship in a cell-free system. Correlation of inhibition of folate synthesis with antibacterial activity and physicochemical parameters.
Topics: Aniline Compounds; Anti-Bacterial Agents; Cell-Free System; Depression, Chemical; Escherichia coli; Folic Acid; Folic Acid Antagonists; Kinetics; Magnetic Resonance Spectroscopy; Pteridines; Pyridines; Structure-Activity Relationship; Sulfonamides | 1972 |
Bibliography of paper and thin-layer chromatography 1966-1969. Vitamins.
Topics: Ascorbic Acid; Bibliographies as Topic; Biotin; Chromatography; Chromatography, Paper; Chromatography, Thin Layer; Coenzyme A; Ergocalciferols; Fats; Flavins; Folic Acid; Growth Substances; Nicotinic Acids; Pantothenic Acid; Pteridines; Riboflavin; Solubility; Thiamine; Vitamin B 12; Vitamin E; Vitamin K; Vitamins; Water | 1972 |
Reduction of folate by Ti 3+ .
Topics: Amines; Chemical Phenomena; Chemistry; Chromatography, Gel; Folic Acid; Kinetics; Osmolar Concentration; Oxidation-Reduction; Paraquat; Polarography; Pteridines; Spectrophotometry, Ultraviolet; Temperature; Titanium | 1972 |
Assignment of the carbon-13 nuclear magnetic resonance spectrum of folic acid.
Topics: Aminobenzoates; Benzamides; Carbon Isotopes; Chemical Phenomena; Chemistry; Deuterium; Folic Acid; Glutamates; Magnetic Resonance Spectroscopy; Protons; Pteridines; Purines; Quinazolines; Quinoxalines; Ribonucleosides | 1973 |
A simple method for preparing 2-amino-4-hydroxy-6-formylpteridine, a precursor of the pteridine substrate of dihydropteroate biosynthesis.
Topics: Amines; Borohydrides; Bromine; Chemical Phenomena; Chemistry; Folic Acid; Oxidation-Reduction; Pteridines | 1973 |
Inhibition of high-affinity glial uptake of 14C-glutamate by folate.
Topics: Animals; Carbon Radioisotopes; Epilepsy; Extracellular Space; Folic Acid; Ganglia, Spinal; Glutamates; Kinetics; Methotrexate; Neuroglia; Phenytoin; Pteridines; Rats | 1974 |
The biosynthesis of folic acid. VII. Enzymatic synthesis of pteridines from guanosine triphosphate.
Topics: Biological Assay; Carbon Isotopes; Catalysis; Chromatography; Chromatography, Paper; Depression, Chemical; Escherichia coli; Folic Acid; Guanine Nucleotides; Pteridines; Spectrophotometry | 1967 |
Binding of the folate substrate to 5-methyltetrahydropteroyltriglutamate-homocysteine transmethylase.
Topics: Benzoates; Binding Sites; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Gel; Escherichia coli; Folic Acid; Glutamates; Homocysteine; Mutation; Peptides; Pteridines; Temperature; Time Factors; Transferases | 1970 |
The biosynthesis of folic acid. X. Evidence for an Amadori rearrangement in the enzymatic formation of dihydroneopterin triphosphate from GTP.
Topics: Amidohydrolases; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Electrophoresis; Escherichia coli; Folic Acid; Formates; Guanine Nucleotides; Kinetics; Paper; Pentosephosphates; Pteridines; Spectrophotometry; Ultraviolet Rays | 1969 |
Aminoacyl formylmethionyl transfer ribonucleic acid transformylase. Inhibitor studies and the reversal of the reaction.
Topics: Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Paper; Escherichia coli; Folic Acid; Formates; Hydrogen-Ion Concentration; Kinetics; Mercaptoethanol; Methionine; Pteridines; RNA, Transfer; Transferases; Tritium | 1970 |
Properties of thymidylate synthetase from dichloromethotrexate-resistant Lactobacillus casei.
Topics: Drug Resistance, Microbial; Enzyme Activation; Escherichia coli; Folic Acid; Glutamates; Kinetics; Lactobacillus; Mercaptoethanol; Methotrexate; Methylation; Molecular Weight; Pteridines; Spectrophotometry; Transferases; Tritium; Uracil Nucleotides | 1970 |
A comparison of the effectiveness with which p-aminobenzoic acid and p-aminobenzoylglutamic acid are used as substrate by dihydropteroate synthetase from Escherichia coli.
Topics: Aminobenzoates; Escherichia coli; Folic Acid; Glutamates; Ligases; Pteridines | 1970 |
Folic acid, a structural component of T4 bacteriophage.
Topics: Animals; Chromatography, Paper; Coliphages; Culture Media; Enterococcus faecalis; Escherichia coli; Fluorometry; Folic Acid; In Vitro Techniques; Lactobacillus; Pteridines; Spectrophotometry; Swine; Tryptophan; Viral Proteins | 1965 |
Biosynthesis of folic acid. 3. Characterization of the genetic blocks in the pathway for pterinoid synthesis in microorganisms requiring folic acid.
Topics: Bacillus subtilis; Chromatography, Paper; Enterococcus faecalis; Eukaryota; Folic Acid; Genetics, Microbial; Lactobacillus; Pteridines | 1966 |
[Biosynthesis and metabolism of folic acid and pteridines].
Topics: Aldehydes; Carbon Isotopes; Cell-Free System; Chromatography, Paper; Enterococcus faecalis; Eukaryota; Folic Acid; Leuconostoc; Pteridines; Pterins; Saccharomyces | 1967 |
The biosynthesis of folic acid compounds in plants. I. Enzymatic formation of dihydropteroic acid and dihydrofolic acid from 2-amino-4-hydroxy-6-substituted pteridines by cell-free extracts of pea seedlings.
Topics: Biological Assay; Cell-Free System; Enterococcus faecalis; Folic Acid; Plants; Pteridines | 1968 |
The biosynthesis of folic acid compounds in plants. II. Some properties of dihydropteroate-synthesizing enzyme in pea seedlings.
Topics: Barium; Biological Assay; Cadmium; Calcium; Cell-Free System; Cobalt; Copper; Enterococcus faecalis; Folic Acid; Hydrogen-Ion Concentration; Iron; Magnesium; Manganese; Mercury; Nickel; Plants; Pteridines | 1968 |
Folate replacement by tetrahydrohomopteroate in triazine-resistant bacteria.
Topics: Bacteriological Techniques; Benzoates; Culture Media; Drug Resistance, Microbial; Enterococcus faecalis; Folic Acid; Glucose; Growth Substances; Proguanil; Pteridines; Triazines | 1971 |
Pterins in human urine.
Topics: Administration, Oral; Animals; Anura; Biological Assay; Chromatography, Ion Exchange; Chromatography, Paper; Diet; Eukaryota; Folic Acid; Humans; Pteridines; Pterins; Purines; Spectrophotometry; Stereoisomerism; Ultraviolet Rays | 1972 |
The urinary excretion of orally administered pteroyl-L-glutamic acid by the rat.
Topics: Administration, Oral; Animals; Antioxidants; Biological Assay; Carbon Isotopes; Chromatography, Thin Layer; Feces; Folic Acid; Kidney; Liver; Male; Pteridines; Rats | 1971 |
[Biochemical processes during kidney regeneration after lesion with pteridine derivatives].
Topics: Animals; Folic Acid; Hypertrophy; Kidney; Kidney Diseases; Organ Size; Pteridines; Rats; Regeneration | 1971 |
Addition of bisulfite to folate and dihydrofolate.
Topics: Chemical Phenomena; Chemical Precipitation; Chemistry; Folic Acid; Hydrogen-Ion Concentration; Models, Chemical; Oxidation-Reduction; Pteridines; Spectrophotometry; Sulfites; Tetrahydrofolate Dehydrogenase | 1967 |
Synthesis of (+ or minus)-5,10-methenyltetrahydrofolic acid-2 14 C and (+ or minus)-5-formyltetrahydrofolic acid-2 14 C.
Topics: Carbon Isotopes; Chromatography, Thin Layer; Folic Acid; Isotope Labeling; Leucovorin; Methods; Oxidation-Reduction; Pteridines; Spectrophotometry; Ultraviolet Rays | 1971 |
Role of 2-amino-4-hydroxypteridine-6-carboxaldehyde in folic acid biosynthesis.
Topics: Aldehydes; Escherichia coli; Folic Acid; Pteridines | 1967 |
Antagonists of growth inhibition of Crithidia by allopurinol, a guanine analog.
Topics: Allopurinol; Folic Acid; Hypoxanthines; Mercaptopurine; Pteridines; Thymidine; Trypanosoma | 1970 |
[Acute renal failure after pteridine administration].
Topics: Acute Kidney Injury; Animals; Anuria; Chlorothiazide; Diuretics; Folic Acid; Furosemide; Glomerular Filtration Rate; Kidney Function Tests; Kidney Tubules; Male; Pteridines; Pyrazines; Rats; Water-Electrolyte Balance; Xanthopterin | 1970 |
Energy-dependent transport of pteridines into the trypanosomid flagellate, Crithidia fasciculata.
Topics: Animals; Biological Transport; Cell Membrane; Chromatography; Cyanides; Dinitrophenols; Energy Transfer; Folic Acid; Folic Acid Antagonists; Potassium; Pteridines; Radioisotopes; Riboflavin; Trypanosoma; Vitamin B Complex | 1970 |
The biosynthesis of folic acid compounds in plants. 3. Distribution of the dihydropteroate-synthesizing enzyme in plants.
Topics: Aminobenzoates; Carbon Isotopes; Cytoplasm; Folic Acid; Glycine max; Ligases; Mitochondria; Plants; Pteridines; Seeds; Vegetables | 1970 |
The therapeutic effect of 2-amino-4-hydroxy-6-(1',2',3',4'-tetrahydroxybutyl)-5,6,7,8-tetrahydropteridine in x-irradiated mice.
Topics: Animals; Folic Acid; Male; Mice; Oxidation-Reduction; Pteridines; Radiation Injuries, Experimental; Radiation-Protective Agents; Radiochemistry | 1971 |
The use of Sephadex for the concentration of pteridines.
Topics: Animals; Chromatography, Ion Exchange; Dextrans; Drosophila; Fluorescence; Fluorometry; Folic Acid; Pteridines; Rhodospirillum; Tetrahymena | 1967 |
[The yeast Rhodotorula flava B-322--an indicator for paraaminobenzoic acid].
Topics: Aminobenzoates; Culture Media; Folic Acid; Glutamates; Indicators and Reagents; Pteridines; Yeasts | 1967 |
The origin of unconjugated pteridines in Crithidia fasciculata.
Topics: Carbon Isotopes; Eukaryota; Folic Acid; Pteridines; Pterins | 1967 |
Absorption and malabsorption of dietary folate.
Topics: Celiac Disease; Diet; Folic Acid; Glutamates; Humans; Intestinal Absorption; Malabsorption Syndromes; Pteridines; Sprue, Tropical | 1968 |
Synthesis of 2-amino-4-hydroxy-6-formyl-7,8-dihydropteridine and its identification as a degradation product of dihydrofolate.
Topics: Folic Acid; Pteridines | 1968 |
The enzymatic hydrolysis of folate analogues.
Topics: Aspartic Acid; Carboxypeptidases; Folic Acid; Glutamates; Methods; Methotrexate; Peptide Hydrolases; Pseudomonas; Pteridines; Soil Microbiology; Spectrophotometry | 1968 |
2,4-diamino-5, 6,7,8-tetrahydroquinazoline, a new pteridine antagonist.
Topics: Animals; Depression, Chemical; Eukaryota; Folic Acid; Growth; Pteridines; Pterins; Quinazolines; Thymidine; Thymine | 1969 |
Pteridine requirement of the hemoflagellate Leishmania tarentolae.
Topics: Animals; Flagella; Folic Acid; Leishmania; Pteridines | 1969 |
Synthesis and properties of 2-amino-4-hydroxy-5,6-dimethyl-5,6,7,8-tetrahydropteridine and the 5,7-dimethyl isomer.
Topics: Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Coenzymes; Folic Acid; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Methods; Methylation; Pteridines; Spectrum Analysis | 1969 |
Analogs of tetrahydrofolic acid XXV. 2,4-Diamino-6-phenethylpteridine, an inhibitor of dihydrofolic reductase.
Topics: Aminopterin; Chemical Phenomena; Chemistry; Enzymes; Folic Acid; Pteridines; Pyrimidines; Tetrahydrofolate Dehydrogenase | 1965 |
The chemical degradation of folic acid. Photolysis of 2,4,7-trihydroxypteridine.
Topics: Chemical Phenomena; Chemistry; Folic Acid; Glyoxylates; Light; Pteridines; Ultraviolet Rays | 1966 |
The dissociation constants of tetrahydrofolic acid.
Topics: Chemical Phenomena; Chemistry; Folic Acid; Glutamates; Hydrogen-Ion Concentration; Pteridines; Spectrophotometry | 1966 |
Biochemical studies on pteridines in plants. II. Biogenesis of folic acid in green leaves: enzymatic synthesis of dihydropteroic acid from guanosine compounds and mechanism of its synthetic pathway.
Topics: Adenosine Triphosphate; Aminobenzoates; Benzoates; Chemistry, Organic; Folic Acid; Guanine Nucleotides; Magnesium; Nucleosides; Organic Chemistry Phenomena; Plants; Pteridines | 1966 |
A chemically prepared formamidopyrimidine derivative of guanosine triphosphate as a possible intermediate in pteridine biosynthesis.
Topics: Chemistry, Organic; Chromatography; Folic Acid; Guanine Nucleotides; Iron; Lactobacillus; Mercaptoethanol; Organic Chemistry Phenomena; Pteridines | 1967 |
Molecular orbital calculations on folic acid and folic acid analogs.
Topics: Chemical Phenomena; Chemistry, Physical; Folic Acid; Folic Acid Antagonists; Pteridines; Tetrahydrofolate Dehydrogenase | 1967 |
2-amino-4-hydroxy-6-methyl-7,8-dihydropteridine as a model for dihydrofolate.
Topics: Chemical Phenomena; Chemistry; Chromatography; Folic Acid; Hydrogen-Ion Concentration; Models, Chemical; Pteridines; Spectrum Analysis | 1967 |
The influence of ascorbic acid and tetrahydropteridine on the synthesis of hydroxyproline by cultured cells.
Topics: Animals; Ascorbic Acid; Carbon Isotopes; Culture Media; Culture Techniques; Dactinomycin; Folic Acid; Hydroxyproline; Mercaptoethanol; Mice; Mitosis; Pteridines; RNA; RNA, Messenger | 1967 |
Melanin: the organizing molecule.
Topics: Animals; Central Nervous System; Chemical Phenomena; Chemistry; Endocrine Glands; Folic Acid; Glycoproteins; Glycosaminoglycans; Homeostasis; Humans; Melanins; Methylation; Neurotransmitter Agents; Polyamines; Pteridines; Purines | 1983 |
The effect of folic acid on cAMP-elicited cAMP production in Dictyostelium discoideum.
Topics: Adaptation, Physiological; Chemotactic Factors; Cyclic AMP; Dictyostelium; Folic Acid; Pteridines | 1983 |
Folic acid does not inactivate xanthine oxidase.
Topics: Animals; Cattle; Female; Folic Acid; Kinetics; Milk; Pteridines; Pterins; Xanthine Oxidase | 1984 |
Inhibition of mammalian xanthine oxidase by folate compounds and amethopterin.
Topics: Allopurinol; Animals; Cattle; Folic Acid; Kinetics; Leucovorin; Methotrexate; Pteridines; Tetrahydrofolates; Time Factors; Xanthine Oxidase | 1984 |
Characterization of the folic acid C9-N10-cleaving enzyme of Dictyostelium minutum V3.
Topics: Aminohydrolases; Dictyostelium; Folic Acid; Glutamates; Hydrogen-Ion Concentration; Kinetics; Protozoan Proteins; Pteridines; Pterins; Species Specificity | 1983 |
Bacterial degradation of folic acid.
Topics: Carboxypeptidases; Folic Acid; gamma-Glutamyl Hydrolase; Pseudomonas; Pteridines; Substrate Specificity | 1980 |
Pteridines as nonretinal regulators of light-dependent melatonin biosynthesis.
Topics: Acetylserotonin O-Methyltransferase; Animals; Cattle; Folic Acid; Light; Melatonin; Methyltransferases; Photochemistry; Pineal Gland; Pteridines; Pterins | 1980 |
Methotrexate and folate binding to dihydrofolate reductase. Separate characterization of the pteridine and p-aminobenzoyl binding sites by resonance Raman spectroscopy.
Topics: Binding Sites; Escherichia coli; Folic Acid; Methotrexate; Protein Binding; Pteridines; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase | 1981 |
Enzymic characterization of Bacillus subtilis GTP cyclohydrolase I. Evidence for a chemical dephosphorylation of dihydroneopterin triphosphate.
Topics: Bacillus subtilis; Base Sequence; Binding, Competitive; Calcium; Folic Acid; Gene Expression; GTP Cyclohydrolase; Guanosine Triphosphate; Kinetics; Magnesium; Molecular Sequence Data; Neopterin; Operon; Phosphorylation; Plasmids; Potassium; Promoter Regions, Genetic; Pteridines; Recombinant Proteins; Uridine Triphosphate | 1995 |
Proceedings of the 10th International Symposium on Chemistry and Biology of Pteridines and Folates. Orange Beach, Alabama, March 21-26, 1993.
Topics: Animals; Folic Acid; Humans; Pteridines | 1993 |
Intermediates in the folic acid biosynthetic pathway are incorporated into molybdopterin the yeast, Pichia canadensis.
Topics: Coenzymes; Folic Acid; Glucose; Guanosine; Metalloproteins; Molybdenum Cofactors; Pichia; Pteridines; Pterins | 1994 |
13C NMR determination of the tautomeric and ionization states of folate in its complexes with Lactobacillus casei dihydrofolate reductase.
Topics: Binding Sites; Carbon Isotopes; Folic Acid; Ions; Lacticaseibacillus casei; Magnetic Resonance Spectroscopy; Pteridines; Stereoisomerism; Tetrahydrofolate Dehydrogenase | 1993 |
The roles of pteridine reductase 1 and dihydrofolate reductase-thymidylate synthase in pteridine metabolism in the protozoan parasite Leishmania major.
Topics: Animals; Biopterins; Blotting, Western; Chromatography, Gel; Folic Acid; Folic Acid Antagonists; Humans; Hydrogen-Ion Concentration; Kinetics; Leishmania major; Methotrexate; Models, Chemical; Multienzyme Complexes; NADP; Oxidoreductases; Pteridines; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase | 1997 |
Phenytoin-induced depletion of folate in rats originates in liver and involves a mechanism that does not discriminate folate form.
Topics: Administration, Oral; Animals; Anticonvulsants; Bile; Brain Chemistry; Diet; Dose-Response Relationship, Drug; Folic Acid; Glutamates; Intestinal Mucosa; Liver; Male; Phenytoin; Pteridines; Random Allocation; Rats; Rats, Sprague-Dawley; Time Factors | 1997 |
Increased transport of pteridines compensates for mutations in the high affinity folate transporter and contributes to methotrexate resistance in the protozoan parasite Leishmania tarentolae.
Topics: Animals; Biological Transport; Carrier Proteins; Cloning, Molecular; Dose-Response Relationship, Drug; Drug Resistance; Folate Receptors, GPI-Anchored; Folic Acid; Genes, Protozoan; Leishmania; Methotrexate; Models, Biological; Molecular Sequence Data; Mutation; Pteridines; Receptors, Cell Surface | 1999 |
Analysis of folate form distribution by affinity followed by reversed- phase chromatography with electrical detection.
Topics: Animals; Brain Chemistry; Cell Extracts; Chromatography, High Pressure Liquid; Electrochemistry; Folic Acid; Glutamates; Liver; Mice; Pteridines; Rats; Sensitivity and Specificity; Tissue Extracts | 2000 |
Photodegradation of folic acid in aqueous solution.
Topics: Chromatography, High Pressure Liquid; Folic Acid; Glutamates; Hydrogen-Ion Concentration; Kinetics; Photolysis; Pteridines; Solutions; Ultraviolet Rays; Water | 1999 |
Mechanism of the antimicrobial drug trimethoprim revisited.
Topics: 4-Aminobenzoic Acid; Anti-Bacterial Agents; Escherichia coli; Folic Acid; Folic Acid Antagonists; Pteridines; Tetrahydrofolates; Trimethoprim | 2000 |
Pteridine salvage throughout the Leishmania infectious cycle: implications for antifolate chemotherapy.
Topics: Animals; Biopterins; Carrier Proteins; Chromatography, High Pressure Liquid; Folic Acid; Folic Acid Antagonists; Gene Expression Regulation, Developmental; Humans; Leishmania; Leishmaniasis; Membrane Transport Proteins; Molecular Sequence Data; Multienzyme Complexes; Oxidoreductases; Protozoan Proteins; Pteridines; RNA, Messenger; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase | 2001 |
Target analogue imprinted polymers with affinity for folic acid and related compounds.
Topics: Folic Acid; Methotrexate; Polymers; Pteridines | 2001 |
Quantitative analysis of the behavior of Dictyostelium discoideum amoebae: stringency of pteridine reception.
Topics: Animals; Behavior, Animal; Carrier Proteins; Chemotaxis; Dictyostelium; Folate Receptors, GPI-Anchored; Folic Acid; Phosphates; Population Surveillance; Pseudopodia; Pteridines; Receptors, Cell Surface; Sensitivity and Specificity; Signal Transduction | 2002 |
Syntheses of labeled vitamers of folic acid to be used as internal standards in stable isotope dilution assays.
Topics: 4-Aminobenzoic Acid; Chromatography, High Pressure Liquid; Deuterium; Folic Acid; Glutamic Acid; Isotope Labeling; Leucovorin; Magnetic Resonance Spectroscopy; Pteridines; Pterins; Spectrometry, Mass, Electrospray Ionization; Tetrahydrofolates | 2002 |
Fluorescence of pterin, 6-formylpterin, 6-carboxypterin and folic acid in aqueous solution: pH effects.
Topics: Fluorescence; Folic Acid; Hydrogen-Ion Concentration; Pteridines; Pterins; Solutions; Time Factors | 2002 |
The biological functions of pteridine derivatives.
Topics: Biochemical Phenomena; Folic Acid; Humans; Pteridines | 1953 |
Detection and measurement of antagonism to folic acid.
Topics: Folic Acid; Folic Acid Antagonists; Leucovorin; Methotrexate; Pteridines | 1957 |
The role of polyglutamyl pteridine coenzymes in serine metabolism. III. The enzymatic formation of dihydrofolic acid and dihydroteropterin.
Topics: Clostridium; Coenzymes; Folic Acid; Folic Acid Antagonists; Humans; Pteridines; Serine | 1958 |
The nature of the primary oxidation product formed from tetrahydropteridines during phenylalanine hydroxylation.
Topics: Folic Acid; Humans; Hydroxylation; Oxidation-Reduction; Phenylalanine; Pteridines | 1961 |
[On the induction of phenylketonuria in rats and its influencing by folic acid and other pteridine derivatives].
Topics: Animals; Folic Acid; Phenylketonurias; Pteridines; Pterins; Rats | 1963 |
A NEW PTERIDINE-REQUIRING ENZYME SYSTEM FOR THE OXIDATION OF GLYCERYL ETHERS.
Topics: Alcohols; Aldehydes; Chromatography; Ethers; Fatty Acids; Folic Acid; Glycerol; Glyceryl Ethers; Liver; Methotrexate; NAD; NADP; Oxidation-Reduction; Oxidoreductases; Pteridines; Pterins; Rats; Research; Stearic Acids | 1964 |
BIOCHEMICAL STUDIES ON PTERIDINES IN PLANTS. I. BIOGENESIS OF FOLIC ACID IN GREEN LEAVES: CONFIRMATION OF ENZYMATIC SYNTHESIS OF FOLATE COMPOUNDS BY THE ENZYME SYSTEM FROM THE SPINACH.
Topics: 4-Aminobenzoic Acid; Enzyme Inhibitors; Folic Acid; Glutamates; Glycine max; Nucleotides; Pharmacology; Plant Leaves; Plants; Plants, Edible; Pteridines; Pterins; Research; Spinacia oleracea | 1965 |
Enzymatic formation of the pteridine moiety of folic acid from guanine compounds.
Topics: Folic Acid; Guanine; Humans; Nucleosides; Nucleotides; Pteridines; Pterins | 1962 |
[Relations between the fluorescent spectra of folic acid and of other pteridins in aqueous solution].
Topics: Coloring Agents; Folic Acid; Humans; Pteridines | 1950 |
Folate biofortification in tomatoes by engineering the pteridine branch of folate synthesis.
Topics: Aldehyde-Lyases; Amino Acid Sequence; Base Sequence; Chemical Engineering; DNA, Complementary; Folic Acid; Fruit; Genetic Vectors; Molecular Sequence Data; Open Reading Frames; Pteridines | 2004 |
A nudix enzyme removes pyrophosphate from dihydroneopterin triphosphate in the folate synthesis pathway of bacteria and plants.
Topics: Amino Acid Sequence; Diphosphates; Escherichia coli; Folic Acid; Kinetics; Lactococcus lactis; Magnesium; Manganese; Molecular Sequence Data; Neopterin; Nudix Hydrolases; Open Reading Frames; Phylogeny; Plants; Pteridines; Pyrophosphatases; Substrate Specificity | 2005 |
Fluorometry of hydrogen peroxide using oxidative decomposition of folic acid.
Topics: Carcinogens; Cations, Divalent; Copper; Fluorometry; Folic Acid; Hydrogen Peroxide; Oxidation-Reduction; Pteridines; Reactive Oxygen Species; Semicarbazides; Sodium Hypochlorite; Time Factors | 2006 |
Determination of dissociation constants of folic acid, methotrexate, and other photolabile pteridines by pressure-assisted capillary electrophoresis.
Topics: Electrophoresis, Capillary; Folic Acid; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Methotrexate; Osmolar Concentration; Photochemistry; Potentiometry; Pressure; Pteridines; Spectrophotometry, Ultraviolet | 2006 |
Polymeric receptors for the recognition of folic acid and related compounds via substructure imprinting.
Topics: Acrylamides; Binding Sites; Carboxylic Acids; Chromatography, High Pressure Liquid; Folic Acid; Glutamic Acid; Hydrogen-Ion Concentration; Polymers; Pteridines; Pyridines; Urea; Vitamin B Complex | 2006 |
Undiagnosed coeliac disease and nutritional deficiencies in adults screened in primary health care.
Topics: Adolescent; Adult; Autoantibodies; Celiac Disease; Female; Folic Acid; GTP-Binding Proteins; HLA-DQ Antigens; Humans; Immunoglobulin A; Iron; Male; Malnutrition; Middle Aged; Primary Health Care; Protein Glutamine gamma Glutamyltransferase 2; Pteridines; Receptors, Transferrin; Transglutaminases | 2007 |
5-Methyltetrahydrofolate inhibits photosensitization reactions and strand breaks in DNA.
Topics: Ascorbic Acid; Chromatography, High Pressure Liquid; Depression, Chemical; DNA Breaks; DNA Damage; DNA, Superhelical; Folic Acid; Free Radical Scavengers; Oxidation-Reduction; Pentetic Acid; Photochemistry; Photosensitizing Agents; Pteridines; Rose Bengal; Singlet Oxygen; Sodium Azide; Superoxide Dismutase; Tetrahydrofolates; Ultraviolet Rays | 2007 |
Folate biofortification of tomato fruit.
Topics: Carbon; Carbon-Nitrogen Ligases; Crosses, Genetic; Ethylenes; Folic Acid; Food, Fortified; Genetic Engineering; Genetic Techniques; Genetic Vectors; Plants, Genetically Modified; Pteridines; RNA, Plant; Solanum lycopersicum; Tetrahydrofolates; Transaminases; Vitamins | 2007 |
Discovery of potent pteridine reductase inhibitors to guide antiparasite drug development.
Topics: Animals; Antiprotozoal Agents; Crystallography, X-Ray; Drug Design; Drug Evaluation, Preclinical; Enzyme Inhibitors; Folic Acid; Isonipecotic Acids; Leishmania major; Oxidoreductases; Parasitic Sensitivity Tests; Protozoan Proteins; Pteridines; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase; Trypanocidal Agents; Trypanosoma cruzi | 2008 |
PTR1-dependent synthesis of tetrahydrobiopterin contributes to oxidant susceptibility in the trypanosomatid protozoan parasite Leishmania major.
Topics: Animals; Biopterins; Drug Resistance; Folic Acid; Hydrogen Peroxide; Leishmania major; Methylnitronitrosoguanidine; Molsidomine; Multienzyme Complexes; Mutation; Nitric Oxide Donors; Nitroso Compounds; Oxidants; Oxidoreductases; Protozoan Proteins; Pteridines; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase | 2009 |
Photoinduced electron transfer in folic acid investigated by ultrafast infrared spectroscopy.
Topics: Anions; Dimethyl Sulfoxide; Electron Transport; Folic Acid; Glutamates; Hydrogen-Ion Concentration; Pteridines; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Thermodynamics; Water | 2012 |
Weak interactions between folate and osmolytes in solution.
Topics: 4-Aminobenzoic Acid; Binding Sites; Dimerization; Dimethyl Sulfoxide; Folic Acid; Kinetics; Osmolar Concentration; Pteridines; Solutions; Tetrahydrofolate Dehydrogenase | 2012 |
Folic acid and its photoproducts, 6-formylpterin and pterin-6-carboxylic acid, as generators of reactive oxygen species in skin cells during UVA exposure.
Topics: Cell Line; Cell Survival; Chromatography, High Pressure Liquid; Folic Acid; Humans; Keratinocytes; Photolysis; Pteridines; Pterins; Reactive Oxygen Species; Ultraviolet Rays | 2016 |
Synthesis, In Silico Prediction and In Vitro Evaluation of Antitumor Activities of Novel Pyrido[2,3-
Topics: A549 Cells; Antineoplastic Agents; Binding Sites; Chemistry Techniques, Synthetic; Cyclin-Dependent Kinase 2; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Folic Acid; Humans; Inhibitory Concentration 50; Janus Kinase 2; MCF-7 Cells; Molecular Docking Simulation; Neoplasms; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-mdm2; Pteridines; Pyridines; Pyrimidines; Tetrahydrofolate Dehydrogenase; Tumor Suppressor Protein p53; Xanthine | 2020 |