pteridines and allopurinol

pteridines has been researched along with allopurinol in 102 studies

Research

Studies (102)

TimeframeStudies, this research(%)All Research%
pre-199062 (60.78)18.7374
1990's18 (17.65)18.2507
2000's17 (16.67)29.6817
2010's5 (4.90)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bergmann, F; Levene, L; Rahat, M; Tamir, I1
Hodnett, CN; McCormack, JJ; Sabean, JA1
Knipe, JO; McCormack, JJ1
Icho, T; Kajiwara, Y; Kojima, S; Kubota, K1
Bennett, B; Bray, RC; Howes, BD; Koppenhöfer, A; Lowe, DJ1
Gardlik, S; Rajagopalan, KV1
Bray, RC; Deistung, J1
Barber, MJ; Gardlik, S; Rajagopalan, KV1
Bray, RC; Deistung, J; Ventom, AM1
Fridovich, I; Nagano, T1
Blankenship, PR; Bowyer, F; Hommes, FA; Roesel, RA1
Aukett, A; Bennett, MJ; Hosking, GP1
Kaneda, N; Nagatsu, T; Sasaoka, T1
Oltmann, LF; Stouthamer, AH; van Spanning, RJ; Wansell-Bettenhaussen, CW2
Folkers, G; Krug, M; Trumpp, S1
Bauer, SA; Varma, SD1
Johnson, JL; Kramer, SP; Millington, DS; Rajagopalan, KV; Ribeiro, AA1
Gustmann, H; Koke, HG; Manzke, H; Nyhan, WL1
Granger, DN; Hollwarth, ME; McCord, JM; Parks, DA1
Hille, R; Massey, V1
Bimar, J; Collet, S; Desjacques, P; Divry, P; Lagier, P; Lando, A; Tessonnier, JM; Vianet-Liaud, C1
Berger, JP; Hervé, F; Soulier, J1
Monnet, JP; Nogues, C; Ogier, H; Roth, A; Saudubray, JM1
Glassman, E; Yen, TT1
Watt, WB1
Furumoto, S; Mitsuda, H; Suzuki, Y1
Haddow, A; Ross, WC; Timmis, GM1
Friedman, TB1
Gyure, WL1
Oster, KA; Ptaszynski, M; Ross, DJ1
Cadenhead, A; Cameron, JS; Hatfield, PJ; Jones, AS; Rising, TJ; Simmonds, A1
Cadenhead, A; Cameron, JS; Hatfield, PJ; Jones, AS; Simmonds, HA1
Schlee, D; Zurnieden, K1
Elion, GB; Hitchings, GH; Krenitsky, TA; Neil, SM1
Fisher, JR; Priest, DG1
Collins, JF; Duke, EJ; Glassman, E1
Whiteley, HR; Woolfolk, BS; Woolfolk, CA1
Baker, H; Frank, O; Hutner, SH1
Bergmann, F; Brown, DJ; Levene, L; Neiman, Z1
McCormack, JJ; Valerino, DM2
Gutensohn, W; Rembold, H1
Glassman, E; Keller, EC1
Gibbs, DA; Watts, RW1
Boni, P; Parisi, G1
Haining, JL; Legan, JS1
Bray, RC; Hawkes, TR2
Bray, RC; Malthouse, JP; Williams, JW1
Coughlan, MP1
Fukui, S; Ishizuka, M; Toraya, T; Ushio, K1
Davis, MD; Olson, JS; Palmer, G2
Arison, BH; Hainline, BE; Johnson, JL; Rajagopalan, KV1
Ferone, R; Spector, T1
Bettenhaussen, CW; Claassen, VP; Fokkens, RH; Nibbering, NM; Oltmann, LF; Pinkse, FA; Stouthamer, AH; van 't Riet, J1
Fleary, M; Lewis, AS; McCalla, C; Murphy, L; Purcell, S1
Marr, JJ1
Claassen, VP; Oltmann, LF; Stouthamer, AH; Vader, CE; van 't Riet, J1
Hainline, BE; Johnson, JL; Rajagopalan, KV1
Charpentier, C; Frezal, J; Kesseler, A; Munnich, A; Ogier, H; Perignon, JL; Saudubray, JM1
Bagnara, JT; Yasutomi, M1
Archer, M; Engh, R; Hof, P; Huber, R; LeGall, J; Moura, I; Moura, JJ; Romão, MJ; Schneider, M1
Mandel, H; Stroomer, LE; van Cruchten, AG; van Gennip, AH1
Hille, R; Kim, JH; Knaut, H; Ryan, MG1
Bellini, C; Bertola, A; Bonioli, E; Caruso, U; DiStefano, A; Dorche, C; Fantasia, AR; Minniti, G; Palmieri, A1
Sumi, S; Wada, Y1
Arai, T; Makino, K; Mori, H; Mori, K; Nakao, S; Suzuki, T; Tajima, K; Watanabe, K1
Kisker, C; Rees, DC; Schindelin, H1
Bray, RC; Eisenthal, R; Godber, B; Harrison, R; Sanders, S1
Adachi, T; Arai, T; Endo, N; Ishii, H; Makino, K; Mori, H; Mori, K1
Hosoya, T; Ichida, K1
Huber, R; Knäblein, J; Moura, JJ; Romão, MJ1
Baas, D; Kisker, C; Kroneck, PM; Meckenstock, RU; Rétey, J; Schindelin, H1
Oettl, K; Reibnegger, G1
Angermüller, S; Klipp, W; Leimkühler, S; Mendel, RR; Schwarz, G1
Adams, B; Bray, RC; Canne, C; Fetzner, S; Hüttermann, J; Kappl, R; Lowe, DJ; Smith, AT1
Arai, T; Endo, N; Fukuda, K; Hirota, K; Ishii, H; Makino, K; Mori, H1
Behrens, A; Fryxelius, J; Lorber, C; Nordlander, E; Thapper, A1
Demontis, S; Garattini, E; Kurosaki, M; Marini, M; Salmona, M; Saltini, G; Terao, M1
Arai, T; Endo, N; Fukuda, K; Hirota, K; Ishii, H; Makino, K; Mori, H; Sasada, M; Yamashita, K1
Jones, L; Kim, JH; Odutola, JA; Popham, J; von Laven, S1
Grisham, MB; Jourd'heuil, D; Jourd'heuil, FL; Kutchukian, PS; Musah, RA; Wink, DA1
Hille, R1
Brandsch, R; Sandu, C1
Ichida, K1
Ziegler, I1
BERGMANN, F; KWIETNY, H2
Wu, YD; Zhang, XH1
Cultrone, A; Drevet, C; Fernández-Martín, R; Montero-Morán, G; Rochet, M; Scazzocchio, C1
Choi, EY; Hemann, C; Hille, R; Ilich, P; Stockert, AL1
Horn, I; Lagziel, A; Landau, D; Levartovsky, D; Naamati, MS; Peretz, H; Shalev, H; Shani, E1
Ahmad, T; Ali, S; Farooqui, H; Naime, M; Pawa, S; Prasad, R; Zafar, H1
Boll, M; Ermler, U; Friedrich, T; Johannes, J; Unciuleac, MC; Warkentin, E1
Cao, H; Hille, R; Pauff, JM1
Hwang, KC; Tai, LA1
Cantu-Medellin, N; Choughule, KV; Jones, JP; Kelley, EE; Schoenborn, SO; Weidert, ER1
Azarov, I; Basu, P; Gauthier, MC; Gladwin, MT; Merchant, BA; Ragireddy, V; Sparacino-Watkins, CE; Sun, B; Tejero, J; Thomas, J; Wang, J1
Li, J; Ryde, U1
Dhiman, P; Khatkar, A; Malik, N1

Reviews

10 review(s) available for pteridines and allopurinol

ArticleYear
[Biochemistry and physiology of the flavinogenesis in microorganisms].
    Die Pharmazie, 1970, Volume: 25, Issue:11

    Topics: Adenine; Bacteria; Biotransformation; Catalysis; Chemical Phenomena; Chemistry; Coenzymes; Enzyme Activation; Enzyme Repression; Flavonoids; Folic Acid; Fungi; Glycosides; Guanine Nucleotides; Lactates; Phosphates; Pteridines; Purines; Pyrimidines; Riboflavin; Ribose; RNA; Saccharomyces; Uracil; Xanthine Oxidase; Xanthines

1970
[Xanthine oxidase deficiency (hereditary xanthinuria), molybdenum cofactor deficiency].
    Nihon rinsho. Japanese journal of clinical medicine, 1996, Volume: 54, Issue:12

    Topics: Central Nervous System Diseases; Coenzymes; Diagnosis, Differential; Diet Therapy; Humans; Infant, Newborn; Metalloproteins; Molybdenum Cofactors; Pteridines; Purine-Pyrimidine Metabolism, Inborn Errors; Seizures; Uric Acid; Xanthine; Xanthine Oxidase; Xanthines

1996
Molybdenum-cofactor-containing enzymes: structure and mechanism.
    Annual review of biochemistry, 1997, Volume: 66

    Topics: Aldehyde Oxidoreductases; Animals; Bacteria; Coenzymes; Humans; Iron-Sulfur Proteins; Metalloproteins; Molybdenum; Molybdenum Cofactors; Oxidoreductases; Oxidoreductases Acting on Sulfur Group Donors; Protein Conformation; Pteridines; Xanthine Oxidase

1997
[Molybdenum cofactor deficiency].
    Ryoikibetsu shokogun shirizu, 1998, Issue:18 Pt 1

    Topics: Aldehyde Oxidase; Aldehyde Oxidoreductases; Amino Acid Metabolism, Inborn Errors; Coenzymes; Diagnosis, Differential; Humans; Metalloproteins; Molybdenum Cofactors; Oxidoreductases Acting on Sulfur Group Donors; Prognosis; Pteridines; Purine-Pyrimidine Metabolism, Inborn Errors; Xanthine Oxidase

1998
Structure and function of molybdopterin containing enzymes.
    Progress in biophysics and molecular biology, 1997, Volume: 68, Issue:2-3

    Topics: Coenzymes; Crystallography, X-Ray; Desulfovibrio; Escherichia coli; Iron-Sulfur Proteins; Metalloproteins; Models, Molecular; Molybdenum; Molybdenum Cofactors; Oxidoreductases; Oxidoreductases Acting on Sulfur Group Donors; Protein Conformation; Pteridines; Rhodobacter sphaeroides; Xanthine Oxidase

1997
A structural comparison of molybdenum cofactor-containing enzymes.
    FEMS microbiology reviews, 1998, Volume: 22, Issue:5

    Topics: Bacteria, Anaerobic; Coenzymes; Humans; Hydro-Lyases; Metalloproteins; Mixed Function Oxygenases; Molybdenum; Molybdenum Cofactors; Oxidoreductases; Oxidoreductases Acting on Sulfur Group Donors; Pteridines; Tungsten; Xanthine Oxidase

1998
Molybdenum and tungsten in biology.
    Trends in biochemical sciences, 2002, Volume: 27, Issue:7

    Topics: Aldehyde Oxidoreductases; Animals; Bacterial Proteins; Binding Sites; Coenzymes; Formate Dehydrogenases; Iron-Sulfur Proteins; Metalloproteins; Models, Molecular; Molecular Structure; Molybdenum; Molybdenum Cofactors; Oxidoreductases; Oxidoreductases Acting on Sulfur Group Donors; Protein Structure, Tertiary; Pteridines; Tungsten; Xanthine Oxidase

2002
[Primary underproductive hypouricemia].
    Nihon rinsho. Japanese journal of clinical medicine, 2003, Volume: 61 Suppl 1

    Topics: Allopurinol; Coenzymes; Diagnosis, Differential; Humans; Liver Diseases; Metalloproteins; Molybdenum Cofactors; Prognosis; Pteridines; Purine-Nucleoside Phosphorylase; Purine-Pyrimidine Metabolism, Inborn Errors; Ribose-Phosphate Pyrophosphokinase; Uric Acid; Xanthine

2003
The pteridine pathway in zebrafish: regulation and specification during the determination of neural crest cell-fate.
    Pigment cell research, 2003, Volume: 16, Issue:3

    Topics: Animals; Biopterins; Cell Lineage; Gene Expression Regulation, Developmental; GTP Cyclohydrolase; Guanosine Triphosphate; Melanophores; Models, Biological; Models, Chemical; Mutation; Neural Crest; Neurons; Phenotype; Pigments, Biological; Pteridines; Pterins; Signal Transduction; Time Factors; Tyrosine; Xanthine Dehydrogenase; Xanthine Oxidase; Xanthopterin; Zebrafish

2003
In Silico and 3D QSAR Studies of Natural Based Derivatives as Xanthine Oxidase Inhibitors.
    Current topics in medicinal chemistry, 2019, Volume: 19, Issue:2

    Topics: Anthraquinones; Biological Products; Coenzymes; Computer Simulation; Computer-Aided Design; Drug Design; Enzyme Inhibitors; Flavin-Adenine Dinucleotide; Flavonoids; Iron-Sulfur Proteins; Metalloproteins; Molecular Docking Simulation; Molybdenum Cofactors; Protein Conformation; Pteridines; Quantitative Structure-Activity Relationship; Xanthine Oxidase; Xanthones

2019

Other Studies

92 other study(ies) available for pteridines and allopurinol

ArticleYear
Oxidation of methyl derivatives of pteridin-4-one, lumazine and related pteridines by bovine milk xanthine oxidase.
    Biochimica et biophysica acta, 1977, Jan-11, Volume: 480, Issue:1

    Topics: Animals; Cattle; Female; Hydrogen-Ion Concentration; Ketones; Kinetics; Milk; Pteridines; Structure-Activity Relationship; Xanthine Oxidase

1977
Oxidation of selected pteridine derivatives by mamalian liver xanthine oxidase and aldehyde oxidase.
    Journal of pharmaceutical sciences, 1976, Volume: 65, Issue:8

    Topics: Aldehyde Oxidoreductases; Animals; Cytochrome c Group; In Vitro Techniques; Liver; Oxidation-Reduction; Pteridines; Rabbits; Rats; Xanthine Oxidase

1976
Oxidation of pteridine derivatives in mice.
    Biochemical pharmacology, 1977, Dec-01, Volume: 26, Issue:23

    Topics: Animals; Cattle; Feces; Female; Kidney; Kinetics; Liver; Mice; Milk; Oxidation-Reduction; Pteridines; Rabbits; Xanthine Oxidase

1977
Neopterin as an endogenous antioxidant.
    FEBS letters, 1992, Jun-15, Volume: 304, Issue:2-3

    Topics: Alloxan; Animals; Antioxidants; Biopterins; Blood Glucose; Diabetes Mellitus, Experimental; Male; Mice; Neopterin; Pteridines; Superoxide Dismutase; Superoxides; Xanthine Oxidase

1992
31P ENDOR studies of xanthine oxidase: coupling of phosphorus of the pterin cofactor to molybdenum (V).
    Biochemistry, 1991, Apr-23, Volume: 30, Issue:16

    Topics: Animals; Cattle; Coenzymes; Electron Spin Resonance Spectroscopy; Female; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Metalloproteins; Milk; Molybdenum; Molybdenum Cofactors; Phosphorus; Protein Binding; Pteridines; Xanthine Oxidase

1991
The state of reduction of molybdopterin in xanthine oxidase and sulfite oxidase.
    The Journal of biological chemistry, 1990, Aug-05, Volume: 265, Issue:22

    Topics: Animals; Cattle; Chickens; Coenzymes; Female; Liver; Metalloproteins; Milk; Molecular Structure; Molybdenum; Molybdenum Cofactors; Oxidation-Reduction; Oxidoreductases; Oxidoreductases Acting on Sulfur Group Donors; Pteridines; Rats; Spectrophotometry; Xanthine Oxidase

1990
Isolation, in the intact state, of the pterin molybdenum cofactor from xanthine oxidase.
    The Biochemical journal, 1989, Oct-15, Volume: 263, Issue:2

    Topics: Animals; Chromatography, Gel; Chromatography, Ion Exchange; Coenzymes; Drug Stability; Hydrogen-Ion Concentration; Metalloproteins; Milk; Molecular Weight; Molybdenum Cofactors; Potassium Chloride; Protein Denaturation; Pteridines; Sodium Dodecyl Sulfate; Solubility; Solutions; Xanthine Oxidase

1989
A molybdopterin-free form of xanthine oxidase.
    Archives of biochemistry and biophysics, 1987, Volume: 259, Issue:2

    Topics: Animals; Cattle; Chromatography, Affinity; Circular Dichroism; Coenzymes; Electron Spin Resonance Spectroscopy; Iron; Metalloproteins; Microwaves; Milk; Molybdenum Cofactors; Pteridines; Xanthine Oxidase

1987
The isolation of demolybdo xanthine oxidase from bovine milk.
    The Biochemical journal, 1988, Nov-01, Volume: 255, Issue:3

    Topics: Animals; Chromatography, Affinity; Coenzymes; Electron Spin Resonance Spectroscopy; Flavin-Adenine Dinucleotide; Metalloproteins; Milk; Molybdenum; Molybdenum Cofactors; NAD; Pteridines; Spectrophotometry; Xanthine Oxidase

1988
Superoxide radical from xanthine oxidase acting upon lumazine.
    Journal of free radicals in biology & medicine, 1985, Volume: 1, Issue:1

    Topics: Acetaldehyde; Free Radicals; Hydrogen-Ion Concentration; Kinetics; Oxidation-Reduction; Pteridines; Superoxides; Xanthine Oxidase

1985
Combined xanthine and sulphite oxidase defect due to a deficiency of molybdenum cofactor.
    Journal of inherited metabolic disease, 1986, Volume: 9, Issue:4

    Topics: Coenzymes; Humans; Infant, Newborn; Liver; Male; Metabolism, Inborn Errors; Metalloproteins; Molybdenum Cofactors; Oxidoreductases; Oxidoreductases Acting on Sulfur Group Donors; Pteridines; Sulfites; Xanthine; Xanthine Oxidase; Xanthines

1986
Molybdenum co-factor deficiency: an easily missed inborn error of metabolism.
    Developmental medicine and child neurology, 1988, Volume: 30, Issue:4

    Topics: Aldehyde Oxidase; Aldehyde Oxidoreductases; Chromosome Aberrations; Chromosome Disorders; Coenzymes; Female; Genes, Recessive; Humans; Infant; Intellectual Disability; Metalloproteins; Molybdenum Cofactors; Oxidoreductases Acting on Sulfur Group Donors; Pteridines; Purine-Pyrimidine Metabolism, Inborn Errors; Uric Acid; Xanthine Oxidase

1988
Highly sensitive assay for xanthine oxidase activity by high-performance liquid chromatography with fluorescence detection.
    Journal of chromatography, 1988, Feb-26, Volume: 424, Issue:2

    Topics: Animals; Brain; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Kidney; Liver; Pteridines; Rats; Spectrometry, Fluorescence; Xanthine Oxidase; Xanthopterin

1988
The oxidation product of molybdenum cofactor from milk xanthine oxidase.
    Biochemistry international, 1987, Volume: 15, Issue:1

    Topics: Animals; Binding Sites; Cattle; Chromatography, High Pressure Liquid; Coenzymes; Metalloproteins; Milk; Molybdenum Cofactors; Oxidation-Reduction; Pteridines; Spectrometry, Fluorescence; Sulfhydryl Compounds; Time Factors; Xanthine Oxidase

1987
Computer graphic study on models of the molybdenum cofactor of xanthine oxidase.
    Journal of computer-aided molecular design, 1987, Volume: 1, Issue:1

    Topics: Binding Sites; Coenzymes; Computer Graphics; Metalloproteins; Models, Molecular; Molybdenum Cofactors; Pteridines; Xanthine Oxidase

1987
In vitro damage to rat lens by lumazine and xanthine oxidase: prevention by superoxide dismutase.
    Free radical research communications, 1987, Volume: 4, Issue:2

    Topics: Animals; Free Radicals; Hydrogen Peroxide; In Vitro Techniques; Lens, Crystalline; Oxidation-Reduction; Pteridines; Rats; Superoxide Dismutase; Xanthine Oxidase

1987
The structure of the molybdenum cofactor. Characterization of di-(carboxamidomethyl)molybdopterin from sulfite oxidase and xanthine oxidase.
    The Journal of biological chemistry, 1987, Dec-05, Volume: 262, Issue:34

    Topics: Animals; Cattle; Chemical Phenomena; Chemistry, Physical; Chickens; Coenzymes; Magnetic Resonance Spectroscopy; Mass Spectrometry; Metalloproteins; Milk; Molybdenum; Molybdenum Cofactors; Oxidoreductases; Oxidoreductases Acting on Sulfur Group Donors; Pteridines; Pterins; Xanthine Oxidase

1987
Extraction and purification of molybdenum cofactor from milk xanthine oxidase.
    European journal of biochemistry, 1987, Dec-01, Volume: 169, Issue:2

    Topics: Animals; Cattle; Chromatography, High Pressure Liquid; Coenzymes; Female; Glutathione; Kinetics; Metalloproteins; Milk; Molybdenum Cofactors; Pteridines; Sulfhydryl Compounds; Xanthine Oxidase

1987
Hypoxanthine and tetrahydrobiopterin treatment of a patient with features of the Lesch-Nyhan syndrome.
    Advances in experimental medicine and biology, 1986, Volume: 195 Pt A

    Topics: Adult; Allopurinol; Biopterins; Drug Administration Schedule; Humans; Hypoxanthine; Hypoxanthines; Lesch-Nyhan Syndrome; Male; Pteridines; Serotonin

1986
Xanthine oxidase inhibitors attenuate ischemia-induced vascular permeability changes in the cat intestine.
    Gastroenterology, 1986, Volume: 90, Issue:1

    Topics: Animals; Blood Proteins; Capillary Permeability; Cats; Folic Acid; Free Radicals; Ileum; Ischemia; Lymph; Pteridines; Pterins; Time Factors; Xanthine Oxidase

1986
The equilibration of reducing equivalents within milk xanthine oxidase.
    The Journal of biological chemistry, 1986, Jan-25, Volume: 261, Issue:3

    Topics: Animals; Cattle; Chemical Phenomena; Chemistry, Physical; Female; Flavins; Hydrogen-Ion Concentration; Kinetics; Milk; Molybdenum; Oxidation-Reduction; Oxypurinol; Photolysis; Pteridines; Temperature; Xanthine Oxidase

1986
[Combined sulfite and xanthine oxidase deficiency due to an anomaly in the metabolism of molybdenum cofactor].
    Annales de pediatrie, 1986, Volume: 33, Issue:9

    Topics: Coenzymes; Humans; Infant, Newborn; Male; Metabolism, Inborn Errors; Metalloproteins; Molybdenum; Molybdenum Cofactors; Oxidoreductases; Oxidoreductases Acting on Sulfur Group Donors; Pteridines; Sulfites; Uric Acid; Xanthine Oxidase

1986
[Sulfite and xanthine oxidase deficiency: a diagnosis based on 2 simple tests].
    Annales de pediatrie, 1986, Volume: 33, Issue:9

    Topics: Coenzymes; Female; Humans; Infant; Metabolism, Inborn Errors; Metalloproteins; Methods; Molybdenum; Molybdenum Cofactors; Oxidoreductases; Oxidoreductases Acting on Sulfur Group Donors; Pteridines; Sulfites; Uric Acid; Xanthine Oxidase

1986
Anatomo-pathological findings in a case of combined deficiency of sulphite oxidase and xanthine oxidase with a defect of molybdenum cofactor.
    Virchows Archiv. A, Pathological anatomy and histopathology, 1985, Volume: 405, Issue:3

    Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids, Sulfur; Brain; Child, Preschool; Coenzymes; Female; Humans; Liver; Metalloproteins; Microcephaly; Molybdenum; Molybdenum Cofactors; Oxidoreductases; Oxidoreductases Acting on Sulfur Group Donors; Pteridines; Purine-Pyrimidine Metabolism, Inborn Errors; Sulfates; Syndrome; Xanthine Oxidase; Xanthines

1985
Electrophoretic variants of xanthine dehydrogenase in Drosophila melanogaster. II. Enzyme kinetics.
    Biochimica et biophysica acta, 1967, Sep-12, Volume: 146, Issue:1

    Topics: Aldehydes; Animals; Azaguanine; Binding Sites; Drosophila; Electrophoresis; Genes; Kinetics; Methylene Blue; Molecular Biology; Mutation; NAD; Pteridines; Pyridoxal Phosphate; Triazines; Xanthine Oxidase; Xanthines

1967
Xanthine dehydrogenase and pteridine metabolism in Colias butterflies.
    The Journal of biological chemistry, 1972, Mar-10, Volume: 247, Issue:5

    Topics: Allopurinol; Ammonium Sulfate; Animals; Chemical Precipitation; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Electrophoresis; Electrophoresis, Paper; Hypoxanthines; Insecta; Kinetics; NAD; Pteridines; Pterins; Pupa; Purines; Pyrimidines; Uric Acid; Wings, Animal; Xanthine Oxidase; Xanthopterin

1972
An extreme diminution in the strong affinity of 2-amino-4-hydroxy-6-formylpteridine for xanthine oxidase by reduction of a 7, 8-double bond or a formyl group at position 6 of its pyrazine ring.
    Journal of nutritional science and vitaminology, 1974, Volume: 20, Issue:4

    Topics: Amines; Animals; Binding Sites; Binding, Competitive; Kinetics; Mathematics; Milk; Models, Chemical; Oxidation-Reduction; Polarography; Pteridines; Pyrazines; Structure-Activity Relationship; Xanthine Oxidase; Xanthines

1974
The chain of unexpected discovery: xanthopterin-stimulated renal mitosis.
    Perspectives in biology and medicine, 1972,Winter, Volume: 15, Issue:2

    Topics: Animals; Biochemistry; Creativity; History, 20th Century; Hyperplasia; Hypertrophy; Hypoxanthines; Kidney; Kidney Diseases; Mitosis; Pteridines; Purines; Pyrazines; Pyrimidines; Quinoxalines; Rats; Stimulation, Chemical; Structure-Activity Relationship; United Kingdom; Xanthine Oxidase; Xanthopterin

1972
Observations on the regulation of uricase activity during development of Drosophila melanogaster.
    Biochemical genetics, 1973, Volume: 8, Issue:1

    Topics: Allantoin; Animals; Catalase; Drosophila melanogaster; Enzyme Induction; Female; Food Deprivation; Genotype; Hydrogen-Ion Concentration; Hypoxanthines; Larva; Male; Malpighian Tubules; Mutation; Pteridines; Pupa; Purines; Spectrophotometry; Temperature; Urate Oxidase; Xanthine Oxidase; Xanthines; Xanthopterin

1973
Colorimetric determination of certain pteridines and purines.
    Analytical biochemistry, 1973, Volume: 51, Issue:2

    Topics: Aminohydrolases; Aniline Compounds; Animals; Azo Compounds; Colorimetry; Guanine; Methods; Milk; Pteridines; Purines; Sulfonic Acids; Xanthine Oxidase; Xanthines

1973
The presence of ectopic xanthine oxidase in atherosclerotic plaques and myocardial tissues.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1973, Volume: 144, Issue:2

    Topics: Adult; Aged; Amines; Aortic Diseases; Arteriosclerosis; Autopsy; Coronary Disease; Humans; Male; Middle Aged; Myocardium; Pteridines; Xanthine Oxidase

1973
Radioisotope studies of purine metabolism during administration of guanine and allopurinol in the pig.
    Biochemical pharmacology, 1973, Oct-15, Volume: 22, Issue:20

    Topics: Administration, Oral; Allopurinol; Animals; Carbon Radioisotopes; Feces; Guanine; Injections, Intravenous; Nucleic Acids; Pteridines; Purines; Pyrimidines; Swine; Time Factors

1973
Metabolic studies of purine metabolism in the pig during the oral administration of guanine and allopurinol.
    Biochemical pharmacology, 1973, Oct-15, Volume: 22, Issue:20

    Topics: Administration, Oral; Allopurinol; Animals; Appetite; Body Weight; Carbon Radioisotopes; Castration; Diet; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Feedback; Guanine; Histocytochemistry; Kidney Function Tests; Male; Nitrogen; Osmolar Concentration; Pteridines; Purines; Pyrimidines; Swine; Testis; Time Factors; Urea

1973
A comparison of the specificities of xanthine oxidase and aldehyde oxidase.
    Archives of biochemistry and biophysics, 1972, Volume: 150, Issue:2

    Topics: Alcohols; Aldehydes; Amines; Animals; Cattle; Chlorine; Ferricyanides; Imidazoles; Ketones; Kinetics; Liver; Methylamines; Milk; Nitriles; Oxidoreductases; Pteridines; Purines; Pyrazoles; Pyridines; Pyrimidines; Pyrroles; Rabbits; Spectrophotometry; Structure-Activity Relationship; Sulfhydryl Compounds; Sulfides; Sulfones; Thiazoles; Xanthine Oxidase

1972
Nonlinear kinetics of the xanthine oxidase reaction catalyzed by chicken liver xanthine dehydrogenase.
    Archives of biochemistry and biophysics, 1971, Volume: 146, Issue:2

    Topics: Animals; Binding Sites; Chickens; Computers; Kinetics; Liver; Models, Chemical; Pteridines; Xanthine Oxidase; Xanthopterin

1971
Nutritional control of xanthine dehydrogenase. I. The effect in adult Drosophila melanogaster of feeding a high protein diet to larvae.
    Biochimica et biophysica acta, 1970, May-12, Volume: 208, Issue:2

    Topics: Aldehydes; Amidohydrolases; Animals; Antigen-Antibody Reactions; Culture Media; Dietary Proteins; Drosophila; Electrophoresis; Enzyme Activation; Oxidoreductases; Pteridines; Xanthine Oxidase

1970
2-oxypurine dehydrogenase from Micrococcus aerogenes. I. Isolation, specificity, and some chemical and physical properties.
    The Journal of biological chemistry, 1970, Volume: 245, Issue:12

    Topics: Centrifugation, Density Gradient; Fermentation; Hydrogen-Ion Concentration; Kinetics; Methylation; Micrococcus; Oxidoreductases; Oxygen; Pteridines; Purines; Pyridines; Pyrimidines; Xanthine Oxidase; Xanthines

1970
Antagonists of growth inhibition of Crithidia by allopurinol, a guanine analog.
    The Journal of protozoology, 1970, Volume: 17, Issue:2

    Topics: Allopurinol; Folic Acid; Hypoxanthines; Mercaptopurine; Pteridines; Thymidine; Trypanosoma

1970
Oxidation of 7-azapteridines by mammalian xanthine oxidase.
    Biochimica et biophysica acta, 1970, Oct-27, Volume: 222, Issue:1

    Topics: Chemical Phenomena; Chemistry; Pteridines; Spectrum Analysis; Xanthine Oxidase

1970
Xanthine oxidase-mediated oxidation of epinephrine.
    Biochemical pharmacology, 1971, Volume: 20, Issue:1

    Topics: Adrenochrome; Allopurinol; Animals; Catalase; Cattle; Chromatography, Paper; Epinephrine; Female; Fluorescence; Hypoxanthines; Milk; Oxidation-Reduction; Pteridines; Spectrophotometry; Time Factors; Uric Acid; Xanthine Oxidase

1971
6-Hydroxylation of the pteridine ring by xanthine oxidase.
    Biochemical and biophysical research communications, 1968, Jun-10, Volume: 31, Issue:5

    Topics: Animals; Chromatography; Hydrogen-Ion Concentration; Liver; Pteridines; Rats; Spectrophotometry; Xanthine Oxidase

1968
Studies of the oxidation of some aminopteridines by xanthine oxidase.
    Biochimica et biophysica acta, 1969, Jun-17, Volume: 184, Issue:1

    Topics: Allopurinol; Amines; Animals; Chemical Phenomena; Chemistry; Chromatography, Paper; Hydrogen-Ion Concentration; Milk; Oxidation-Reduction; Pteridines; Spectrophotometry; Spectrum Analysis; Ultraviolet Rays; Xanthine Oxidase; Xanthopterin

1969
Phenocopies of the ma-1 and ry mutants of Drosophila melanogaster: inhibition in vivo of xanthine dehydrogenase by 4-hydroxypyrazolo(3,4-d)pyrimidine.
    Nature, 1965, Oct-09, Volume: 208, Issue:5006

    Topics: Animals; Drosophila; Enzymes; Eye; In Vitro Techniques; Mutation; Pigmentation; Pteridines; Xanthine Oxidase

1965
Oxalate formation from glyoxylate in primary hyperoxaluria: studies on liver tissue.
    Clinical science, 1967, Volume: 32, Issue:3

    Topics: Allopurinol; Catalysis; Child; Culture Techniques; Disulfiram; Enzyme Induction; Female; Humans; Liver; Oxalates; Pteridines; Xanthine Oxidase

1967
Abnormalities of the eye pigments (pteridins and ommochromes) induced in Drosophila melanogaster by the inhibitor of xanthine dehydrogenase 4-hydroxypyrazole (3,4 d) pyrimidine.
    Experientia, 1967, Dec-15, Volume: 23, Issue:12

    Topics: Allopurinol; Animals; Chromatography, Paper; Drosophila; Eye; Molecular Biology; Mutation; Pigments, Biological; Pteridines; Spectrophotometry; Xanthine Oxidase; Xanthopterin

1967
Fluorometric assay for xanthine oxidase.
    Analytical biochemistry, 1967, Volume: 21, Issue:3

    Topics: Amines; Animals; Charcoal; Chromatography, Gel; Dialysis; Fluorometry; Liver Extracts; Male; Methods; Milk; Pteridines; Rats; Xanthine Oxidase

1967
Studies by electron-paramagnetic-resonance spectroscopy of the environment of the metal in the molybdenum cofactor of molybdenum-containing enzymes.
    The Biochemical journal, 1984, Sep-15, Volume: 222, Issue:3

    Topics: Chromatography, Gel; Coenzymes; Electron Spin Resonance Spectroscopy; Mercaptoethanol; Metalloproteins; Models, Chemical; Molybdenum; Molybdenum Cofactors; Oxidation-Reduction; Phenols; Pteridines; Sulfhydryl Compounds; Xanthine Oxidase

1984
Quantitative transfer of the molybdenum cofactor from xanthine oxidase and from sulphite oxidase to the deficient enzyme of the nit-1 mutant of Neurospora crassa to yield active nitrate reductase.
    The Biochemical journal, 1984, Apr-15, Volume: 219, Issue:2

    Topics: Apoenzymes; Apoproteins; Coenzymes; Dithiothreitol; Enzyme Activation; Metalloproteins; Methods; Molybdenum; Molybdenum Cofactors; Mutation; NADP; Neurospora; Neurospora crassa; Nitrate Reductase (NADH); Nitrate Reductases; Oxidoreductases; Oxidoreductases Acting on Sulfur Group Donors; Oxygen; Pteridines; Xanthine Oxidase

1984
Molybdenum(V) e.p.r. signals obtained from xanthine oxidase on reduction with aldehyde substrates and with 2-amino-4-hydroxy-6-formylpteridine.
    The Biochemical journal, 1981, Aug-01, Volume: 197, Issue:2

    Topics: Aldehydes; Chemical Phenomena; Chemistry; Electron Spin Resonance Spectroscopy; Molybdenum; Oxidation-Reduction; Pteridines; Pterins; Xanthine Oxidase

1981
The role of molybdenum in human biology.
    Journal of inherited metabolic disease, 1983, Volume: 6 Suppl 1

    Topics: Chemical Phenomena; Chemistry; Coenzymes; Electron Probe Microanalysis; Electron Spin Resonance Spectroscopy; Humans; Metalloproteins; Molybdenum; Molybdenum Cofactors; Pteridines; Xanthine Dehydrogenase; Xanthine Oxidase

1983
Formation of thieno[3,2-g]pterines from the molybdenum cofactor.
    Biochemical and biophysical research communications, 1983, Mar-16, Volume: 111, Issue:2

    Topics: Animals; Cattle; Coenzymes; Escherichia coli; Metalloproteins; Molybdenum; Molybdenum Cofactors; Nitrate Reductases; Pteridines; Pterins; Spectrometry, Fluorescence; Xanthine Oxidase

1983
The reaction of xanthine oxidase with lumazine. Characterization of the reductive half-reaction.
    The Journal of biological chemistry, 1984, Mar-25, Volume: 259, Issue:6

    Topics: Anaerobiosis; Animals; Cattle; Female; Hydrogen-Ion Concentration; Kinetics; Milk; Oxidation-Reduction; Pteridines; Spectrometry, Fluorescence; Xanthine Oxidase

1984
The pterin component of the molybdenum cofactor. Structural characterization of two fluorescent derivatives.
    The Journal of biological chemistry, 1984, May-10, Volume: 259, Issue:9

    Topics: Animals; Chickens; Coenzymes; Liver; Magnetic Resonance Spectroscopy; Mass Spectrometry; Metalloproteins; Molybdenum; Molybdenum Cofactors; Oxidoreductases Acting on Sulfur Group Donors; Pteridines; Rats; Spectrometry, Fluorescence; Spectrophotometry; Xanthine Oxidase

1984
Folic acid does not inactivate xanthine oxidase.
    The Journal of biological chemistry, 1984, Sep-10, Volume: 259, Issue:17

    Topics: Animals; Cattle; Female; Folic Acid; Kinetics; Milk; Pteridines; Pterins; Xanthine Oxidase

1984
Mass spectrometric analysis of fluorescent products originating from the molybdenum cofactor.
    Biochemistry international, 1984, Volume: 8, Issue:1

    Topics: Animals; Cattle; Coenzymes; Female; Mass Spectrometry; Metalloproteins; Milk; Molybdenum; Molybdenum Cofactors; Pteridines; Spectrometry, Fluorescence; Xanthine Oxidase

1984
Inhibition of mammalian xanthine oxidase by folate compounds and amethopterin.
    The Journal of biological chemistry, 1984, Jan-10, Volume: 259, Issue:1

    Topics: Allopurinol; Animals; Cattle; Folic Acid; Kinetics; Leucovorin; Methotrexate; Pteridines; Tetrahydrofolates; Time Factors; Xanthine Oxidase

1984
Pyrazolopyrimidine metabolism in Leishmania: an overview.
    Advances in experimental medicine and biology, 1984, Volume: 165 Pt A

    Topics: Allopurinol; Animals; Antiprotozoal Agents; Hypoxanthine Phosphoribosyltransferase; Leishmania; Pteridines; Purines; Ribonucleosides; Species Specificity

1984
Molybdenum cofactor from the cytoplasmic membrane of Proteus mirabilis.
    Archives of microbiology, 1982, Dec-03, Volume: 133, Issue:4

    Topics: Cell Membrane; Chlorates; Chromatography, Gel; Coenzymes; Cytoplasm; Fluorescence; Metalloproteins; Molybdenum; Molybdenum Cofactors; Mutation; Proteus mirabilis; Pteridines; Xanthine Oxidase

1982
Characterization of the molybdenum cofactor of sulfite oxidase, xanthine, oxidase, and nitrate reductase. Identification of a pteridine as a structural component.
    The Journal of biological chemistry, 1980, Mar-10, Volume: 255, Issue:5

    Topics: Animals; Chickens; Coenzymes; Liver; Metalloproteins; Molybdenum; Molybdenum Cofactors; Nitrate Reductases; Oxidoreductases; Oxidoreductases Acting on Sulfur Group Donors; Pteridines; Rats; Spectrometry, Fluorescence; Spectrophotometry; Xanthine Oxidase

1980
Charge transfer complexes between pteridine substrates and the active center molybdenum of xanthine oxidase.
    The Journal of biological chemistry, 1982, Dec-25, Volume: 257, Issue:24

    Topics: Anaerobiosis; Animals; Binding Sites; Cattle; Dithionite; Female; Kinetics; Milk; Molybdenum; Oxidation-Reduction; Pteridines; Spectrophotometry; Xanthine Oxidase

1982
[Double deficiency of sulfite and xanthine oxidase causing encephalopathy and due to a hereditary anomaly in the metabolism of molybdenum].
    Annales de medecine interne, 1982, Volume: 133, Issue:8

    Topics: Brain Diseases, Metabolic; Coenzymes; Consanguinity; Female; Humans; Infant; Metalloproteins; Molybdenum; Molybdenum Cofactors; Oxidoreductases; Oxidoreductases Acting on Sulfur Group Donors; Pteridines; Purine-Pyrimidine Metabolism, Inborn Errors; Xanthine Oxidase

1982
Electron microscopic study of leaf frog melanophore differentiation in culture, with special reference to allopurinol effect on pterorhodin formation.
    Cell differentiation, 1982, Volume: 11, Issue:1

    Topics: Allopurinol; Animals; Anura; Melanophores; Metamorphosis, Biological; Organ Culture Techniques; Pigments, Biological; Pteridines; Skin

1982
Crystal structure of the xanthine oxidase-related aldehyde oxido-reductase from D. gigas.
    Science (New York, N.Y.), 1995, Nov-17, Volume: 270, Issue:5239

    Topics: Aldehyde Oxidoreductases; Amino Acid Sequence; Animals; Coenzymes; Crystallization; Crystallography, X-Ray; Cytosine Nucleotides; Desulfovibrio; Drosophila melanogaster; Electron Transport; Hydrogen Bonding; Iron; Ligands; Metalloproteins; Molecular Sequence Data; Molybdenum; Molybdenum Cofactors; Oxidation-Reduction; Protein Conformation; Protein Folding; Protein Structure, Secondary; Pteridines; Pterins; Xanthine; Xanthine Oxidase; Xanthines

1995
Effect of allopurinol on the xanthinuria in a patient with molybdenum cofactor deficiency.
    Advances in experimental medicine and biology, 1994, Volume: 370

    Topics: Allopurinol; Coenzymes; Female; Humans; Male; Metabolism, Inborn Errors; Metalloproteins; Molybdenum; Molybdenum Cofactors; Pteridines; Purine-Pyrimidine Metabolism, Inborn Errors; Xanthine; Xanthine Dehydrogenase; Xanthines

1994
The reductive half-reaction of xanthine oxidase. The involvement of prototropic equilibria in the course of the catalytic sequence.
    The Journal of biological chemistry, 1996, Mar-22, Volume: 271, Issue:12

    Topics: Catalysis; Electron Spin Resonance Spectroscopy; Fluorescent Dyes; Hydrogen-Ion Concentration; Kinetics; Molybdenum; Oxidation-Reduction; Pteridines; Purines; Solvents; Substrate Specificity; Xanthine; Xanthine Oxidase; Xanthines

1996
Combined deficiency of xanthine oxidase and sulphite oxidase due to a deficiency of molybdenum cofactor.
    Journal of inherited metabolic disease, 1996, Volume: 19, Issue:5

    Topics: Coenzymes; Female; Fibroblasts; Humans; Hypoxanthine; Infant; Metabolism, Inborn Errors; Metalloproteins; Molybdenum; Molybdenum Cofactors; Nervous System Diseases; Oxidoreductases Acting on Sulfur Group Donors; Pteridines; Uric Acid; Xanthine; Xanthine Oxidase; Xanthines

1996
Pterin-6-aldehyde, an inhibitor of xanthine oxidase, has superoxide anion radical scavenging activity.
    Biochemical and biophysical research communications, 1997, Apr-17, Volume: 233, Issue:2

    Topics: Biopterins; Chromatography, High Pressure Liquid; Free Radical Scavengers; Free Radicals; Humans; In Vitro Techniques; Magnetic Resonance Spectroscopy; Neopterin; Pteridines; Pterins; Superoxides; Xanthine Oxidase

1997
> or = 95% of xanthine oxidase in human milk is present as the demolybdo form, lacking molybdopterin.
    Biochemical Society transactions, 1997, Volume: 25, Issue:3

    Topics: Coenzymes; Electron Spin Resonance Spectroscopy; Female; Humans; Metalloproteins; Milk, Human; Molybdenum; Molybdenum Cofactors; Pteridines; Xanthine Oxidase

1997
Neuroprotective effects of pterin-6-aldehyde in gerbil global brain ischemia: comparison with those of alpha-phenyl-N-tert-butyl nitrone.
    Neuroscience letters, 1998, Jan-30, Volume: 241, Issue:2-3

    Topics: Animals; Brain Ischemia; Cyclic N-Oxides; Dose-Response Relationship, Drug; Enzyme Inhibitors; Free Radical Scavengers; Gerbillinae; Male; Neurons; Neuroprotective Agents; Nitrogen Oxides; Pteridines; Pterins; Spin Labels; Xanthine Oxidase

1998
Pteridines as inhibitors of xanthine oxidase: structural requirements.
    Biochimica et biophysica acta, 1999, Mar-19, Volume: 1430, Issue:2

    Topics: Dose-Response Relationship, Drug; Isomerism; Kinetics; Neopterin; Pteridines; Structure-Activity Relationship; Xanthine Oxidase

1999
Activity of the molybdopterin-containing xanthine dehydrogenase of Rhodobacter capsulatus can be restored by high molybdenum concentrations in a moeA mutant defective in molybdenum cofactor biosynthesis.
    Journal of bacteriology, 1999, Volume: 181, Issue:19

    Topics: Amino Acid Sequence; Coenzymes; DNA Mutational Analysis; Escherichia coli; Escherichia coli Proteins; Eukaryotic Cells; Guanine Nucleotides; Iron-Sulfur Proteins; Metalloproteins; Models, Biological; Molecular Sequence Data; Molybdenum; Molybdenum Cofactors; Mutagenesis, Insertional; Mutation; Nitrate Reductases; Organometallic Compounds; Oxidoreductases; Pteridines; Rhodobacter capsulatus; Sequence Homology, Amino Acid; Sulfurtransferases; Xanthine; Xanthine Oxidase

1999
Kinetics and interactions of molybdenum and iron-sulfur centers in bacterial enzymes of the xanthine oxidase family: mechanistic implications.
    Biochemistry, 1999, Oct-19, Volume: 38, Issue:42

    Topics: Anisotropy; Bacterial Proteins; Coenzymes; Electron Spin Resonance Spectroscopy; Iron-Sulfur Proteins; Kinetics; Metalloproteins; Mixed Function Oxygenases; Molybdenum Cofactors; Oxidation-Reduction; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Pteridines; Spectrophotometry; Structure-Activity Relationship; Substrate Specificity; Xanthine Oxidase

1999
Effects of 6-formylpterin, a xanthine oxidase inhibitor and a superoxide scavenger, on production of nitric oxide in RAW 264.7 macrophages.
    Biochimica et biophysica acta, 2000, Mar-06, Volume: 1474, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cell Survival; Cyclooxygenase 2; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Interferon-gamma; Isoenzymes; Lipopolysaccharides; Luciferases; Macrophages; Mice; Molecular Structure; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Prostaglandin-Endoperoxide Synthases; Pteridines; Pterins; RNA, Messenger; Spin Trapping; Superoxides; Xanthine Oxidase

2000
Synthesis and reactivity studies of model complexes for molybdopterin-dependent enzymes.
    Journal of inorganic biochemistry, 2000, Volume: 79, Issue:1-4

    Topics: Animals; Chickens; Coenzymes; Crystallography, X-Ray; Dithionite; Iron-Sulfur Proteins; Kinetics; Liver; Metalloproteins; Models, Chemical; Molybdenum; Molybdenum Cofactors; Oxidation-Reduction; Oxidoreductases; Oxidoreductases Acting on Sulfur Group Donors; Pteridines; Xanthine Oxidase

2000
Cloning of the cDNAs coding for two novel molybdo-flavoproteins showing high similarity with aldehyde oxidase and xanthine oxidoreductase.
    The Journal of biological chemistry, 2000, Sep-29, Volume: 275, Issue:39

    Topics: Aldehyde Oxidase; Aldehyde Oxidoreductases; Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Cloning, Molecular; Coenzymes; Consensus Sequence; Desulfovibrio; DNA, Complementary; Evolution, Molecular; Female; Humans; Male; Metalloproteins; Mice; Mitochondrial Proteins; Molecular Sequence Data; Molybdenum; Molybdenum Cofactors; Oxidoreductases; Phylogeny; Plant Proteins; Pteridines; Recombinant Proteins; Sequence Homology, Amino Acid; Sex Characteristics; Tissue Distribution; Xanthine Oxidase

2000
6-formylpterin, a xanthine oxidase inhibitor, intracellularly generates reactive oxygen species involved in apoptosis and cell proliferation.
    Free radical biology & medicine, 2001, Feb-01, Volume: 30, Issue:3

    Topics: Apoptosis; Catalase; Cell Division; Chelating Agents; Chromatography, High Pressure Liquid; Deferoxamine; Electrochemistry; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; fas Receptor; HL-60 Cells; Humans; Hydrogen Peroxide; Jurkat Cells; NAD; Nucleotides; Oxidation-Reduction; Oxygen Consumption; Pteridines; Pterins; Reactive Oxygen Species; Superoxides; Xanthine Oxidase

2001
Tautomeric energetics of xanthine oxidase substrates: xanthine, 2-oxo-6-methylpurine, and lumazine.
    Journal of inorganic biochemistry, 2001, Volume: 84, Issue:1-2

    Topics: Catalysis; Energy Metabolism; In Vitro Techniques; Isomerism; Pteridines; Purines; Quantum Theory; Substrate Specificity; Thermodynamics; Xanthine; Xanthine Oxidase

2001
Reaction of superoxide and nitric oxide with peroxynitrite. Implications for peroxynitrite-mediated oxidation reactions in vivo.
    The Journal of biological chemistry, 2001, Aug-03, Volume: 276, Issue:31

    Topics: Catalase; Glutathione; Humans; Hypoxanthine; Kinetics; NAD; Nitrates; Nitric Oxide; Nitrogen Oxides; Oxidation-Reduction; Pteridines; Recombinant Proteins; Rhodamines; Spermine; Superoxide Dismutase; Superoxides; Xanthine Oxidase

2001
Evidence for MoeA-dependent formation of the molybdenum cofactor from molybdate and molybdopterin in Escherichia coli.
    Archives of microbiology, 2002, Volume: 178, Issue:6

    Topics: Chromatography, High Pressure Liquid; Coenzymes; Escherichia coli; Escherichia coli Proteins; Metalloproteins; Molybdenum; Molybdenum Cofactors; Neurospora crassa; Nitrate Reductases; Pteridines; Sulfurtransferases; Xanthine Oxidase

2002
Pteridines as substrates of mammalian xanthine oxidase. I. The end-product of the enzymic oxidation of pteridines.
    Biochimica et biophysica acta, 1958, Volume: 28, Issue:3

    Topics: Animals; Biochemical Phenomena; Mammals; Oxidation-Reduction; Oxidoreductases; Pteridines; Pterins; Xanthine Oxidase

1958
Pteridines as substrates of mammalian xanthine oxidase. II. Pathways and rates of oxidation.
    Biochimica et biophysica acta, 1959, Volume: 33, Issue:1

    Topics: Animals; Biochemical Phenomena; Mammals; Oxidation-Reduction; Oxidoreductases; Pteridines; Pterins; Xanthine Oxidase

1959
A theoretical study on the mechanism of the reductive half-reaction of xanthine oxidase.
    Inorganic chemistry, 2005, Mar-07, Volume: 44, Issue:5

    Topics: Coenzymes; Kinetics; Metalloproteins; Models, Chemical; Models, Molecular; Molecular Conformation; Molecular Structure; Molybdenum Cofactors; Pteridines; Substrate Specificity; Xanthine Oxidase

2005
Convergent evolution of hydroxylation mechanisms in the fungal kingdom: molybdenum cofactor-independent hydroxylation of xanthine via alpha-ketoglutarate-dependent dioxygenases.
    Molecular microbiology, 2005, Volume: 57, Issue:1

    Topics: Amino Acid Sequence; Aspergillus nidulans; Base Sequence; Cloning, Molecular; Coenzymes; Dioxygenases; DNA, Complementary; Evolution, Molecular; Fungal Proteins; Fungi; Hydroxylation; Ketoglutaric Acids; Metalloproteins; Molecular Sequence Data; Molybdenum Cofactors; Mutation; Neurospora crassa; Pteridines; Schizosaccharomyces; Sequence Homology, Amino Acid; Xanthine Oxidase

2005
Resonance Raman studies of xanthine oxidase: The reduced enzyme-product complex with violapterin.
    The journal of physical chemistry. B, 2005, Feb-24, Volume: 109, Issue:7

    Topics: Binding Sites; Coenzymes; Deuterium Oxide; Metalloproteins; Models, Chemical; Models, Molecular; Molecular Conformation; Molybdenum; Molybdenum Cofactors; Oxygen; Pteridines; Solvents; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman; Substrate Specificity; Water; Xanthine Oxidase

2005
Identification and characterization of the first mutation (Arg776Cys) in the C-terminal domain of the Human Molybdenum Cofactor Sulfurase (HMCS) associated with type II classical xanthinuria.
    Molecular genetics and metabolism, 2007, Volume: 91, Issue:1

    Topics: Aldehyde Oxidase; Allopurinol; Amino Acid Sequence; Amino Acid Substitution; Arginine; Base Sequence; Coenzymes; Cysteine; Female; Homozygote; Humans; Infant, Newborn; Male; Metalloproteins; Molybdenum Cofactors; Mutation; Pedigree; Phylogeny; Protein Structure, Tertiary; Pteridines; Sequence Alignment; Sulfurtransferases; Xanthine Dehydrogenase; Xanthines

2007
Role of mammalian cytosolic molybdenum Fe-S flavin hydroxylases in hepatic injury.
    Life sciences, 2008, Mar-26, Volume: 82, Issue:13-14

    Topics: Aldehyde Oxidase; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Coenzymes; Cytosol; Female; Flavin Mononucleotide; Liver; Metalloproteins; Molybdenum Cofactors; Necrosis; Oxidative Stress; Pteridines; Rats; Rats, Wistar; Xanthine Oxidase

2008
Inhibitors of the molybdenum cofactor containing 4-hydroxybenzoyl-CoA reductase.
    Biochemistry, 2008, Apr-29, Volume: 47, Issue:17

    Topics: Anions; Azides; Citric Acid; Coenzymes; Crystallography, X-Ray; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Enzyme Reactivators; Kinetics; Metalloproteins; Molybdenum Cofactors; Oxidation-Reduction; Oxidoreductases Acting on CH-CH Group Donors; Pteridines; Thauera; Xanthine Oxidase

2008
Substrate Orientation and Catalysis at the Molybdenum Site in Xanthine Oxidase: CRYSTAL STRUCTURES IN COMPLEX WITH XANTHINE AND LUMAZINE.
    The Journal of biological chemistry, 2009, Mar-27, Volume: 284, Issue:13

    Topics: Animals; Bacterial Proteins; Catalysis; Catalytic Domain; Cattle; Crystallography, X-Ray; Female; Milk; Molybdenum; Protein Structure, Tertiary; Pteridines; Rhodobacter capsulatus; Xanthine; Xanthine Oxidase

2009
Regulation of xanthine oxidase activity by substrates at active sites via cooperative interactions between catalytic subunits: implication to drug pharmacokinetics.
    Current medicinal chemistry, 2011, Volume: 18, Issue:1

    Topics: Adenine; Binding Sites; Catalysis; Catalytic Domain; Dimerization; Enzyme Inhibitors; Humans; Models, Theoretical; Protein Binding; Pteridines; Pterins; Substrate Specificity; Xanthine; Xanthine Oxidase; Xanthopterin

2011
Inhibition of xanthine oxidase by the aldehyde oxidase inhibitor raloxifene: implications for identifying molybdopterin nitrite reductases.
    Nitric oxide : biology and chemistry, 2014, Feb-15, Volume: 37

    Topics: Aldehyde Oxidase; Coenzymes; Dose-Response Relationship, Drug; Enzyme Inhibitors; Metalloproteins; Molybdenum Cofactors; Nitric Oxide; Nitrite Reductases; Pteridines; Raloxifene Hydrochloride; Structure-Activity Relationship; Xanthine Oxidase

2014
Nitrite reductase and nitric-oxide synthase activity of the mitochondrial molybdopterin enzymes mARC1 and mARC2.
    The Journal of biological chemistry, 2014, Apr-11, Volume: 289, Issue:15

    Topics: Amino Acid Sequence; Coenzymes; Cytochrome Reductases; Cytochromes b5; Electron Transport; HEK293 Cells; Humans; Hydrogen-Ion Concentration; Kinetics; Metalloproteins; Mitochondria; Mitochondrial Proteins; Molecular Sequence Data; Molybdenum; Molybdenum Cofactors; Nitric Oxide; Nitric Oxide Synthase; Nitrite Reductases; Nitrites; Oxidoreductases; Oxygen; Pteridines; Recombinant Proteins; Sequence Homology, Amino Acid; Xanthine Oxidase

2014
Comparison of the active-site design of molybdenum oxo-transfer enzymes by quantum mechanical calculations.
    Inorganic chemistry, 2014, Nov-17, Volume: 53, Issue:22

    Topics: Binding Sites; Catalysis; Coenzymes; Computational Biology; Coordination Complexes; Kinetics; Ligands; Metalloproteins; Models, Molecular; Molybdenum; Molybdenum Cofactors; Oxidation-Reduction; Oxidoreductases; Oxygen; Pteridines; Quantum Theory; Sulfite Oxidase; Thermodynamics; Xanthine Oxidase

2014