pteridines has been researched along with 7-benzylamino-6-chloro-2-piperazino-4-pyrrolidinopteridine in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (40.00) | 18.2507 |
| 2000's | 5 (50.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Drees, M; Eisenbrand, G; Zimmermann, R | 1 |
| Augusti-Tocco, G; Campagnolo, L; Giorgi, M | 1 |
| Eisenbrand, G; Fürstenberger, G; Marko, D; Romanakis, K; Steinbauer, B; Zankl, H | 1 |
| Eisenbrand, G; Frank, W; Marko, D; Merz, KH; Regiert, T; Reiss, G | 1 |
| Augusti-Tocco, G; Citro, G; Giorgi, M; Leonetti, C | 1 |
| Cho-Chung, YS; Eisenbrand, G; Habermeyer, M; Hippe, F; Jakobs, S; Marko, D; Wagner, B | 1 |
| Eisenbrand, G; Kunz, C; Marko, D; Merz, KH; Müller, A; Tarasova, N | 1 |
| Gasbarri, A; Giorgi, M; Modica, A; Pacitti, C; Pompili, A | 1 |
| Bao, B; Chedrese, PJ; Clark, A; Fischer, D; Kagan, D; McKenna, SD; Palmer, S; Pietropaolo, M; Tos, EG | 1 |
| Biagioni, S; Cardarelli, S; Cifone, MG; Cinque, B; Galli, F; Giardi, MF; Giorgi, M; Massimi, M; Panera, N; Ragusa, F | 1 |
10 other study(ies) available for pteridines and 7-benzylamino-6-chloro-2-piperazino-4-pyrrolidinopteridine
| Article | Year |
|---|---|
3',5'-Cyclic nucleotide phosphodiesterase in tumor cells as potential target for tumor growth inhibition.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Animals; Anion Exchange Resins; Antineoplastic Agents; Breast Neoplasms; Cell Division; Cell Fractionation; Chromatography, Ion Exchange; Humans; Isoenzymes; Melanoma, Experimental; Mice; Phosphodiesterase Inhibitors; Piperazines; Pteridines; Resins, Synthetic; Tissue Distribution; Tumor Cells, Cultured | 1993 |
Phosphodiesterase specific inhibitors control cell growth of a human neuroepithelioma cell line.
Topics: Cell Division; Humans; Neuroectodermal Tumors, Primitive, Peripheral; Phosphodiesterase Inhibitors; Piperazines; Pteridines; Purinones; Pyrrolidinones; Rolipram; Tumor Cells, Cultured | 1997 |
Induction of apoptosis by an inhibitor of cAMP-specific PDE in malignant murine carcinoma cells overexpressing PDE activity in comparison to their nonmalignant counterparts.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenine; Animals; Carcinoma; Cell Cycle; Cell Division; Cell Size; Cell Transformation, Neoplastic; Cells, Cultured; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; DNA Fragmentation; Isoenzymes; Keratinocytes; Mice; Papilloma; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Piperazines; Pteridines; Pyrrolidinones; Rolipram; Skin Neoplasms; Tumor Cells, Cultured | 1998 |
Synthesis of 7-benzylamino-6-chloro-2-piperazino-4-pyrrolidinopteridine and novel derivatives free of positional isomers. Potent inhibitors of cAMP-specific phosphodiesterase and of malignant tumor cell growth.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Antineoplastic Agents; Cell Division; Crystallography, X-Ray; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Drug Screening Assays, Antitumor; Humans; Hydrolysis; Inhibitory Concentration 50; Isoenzymes; Lung Neoplasms; Mice; Mice, Nude; Phosphodiesterase Inhibitors; Piperazines; Pteridines; Rhodamines; Structure-Activity Relationship; Transplantation, Heterologous; Tumor Cells, Cultured | 1998 |
In vitro and in vivo inhibition of SK-N-MC neuroblastoma growth using cyclic nucleotide phosphodiesterase inhibitors.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Antineoplastic Agents; Cell Division; Male; Mice; Mice, Nude; Neoplasm Transplantation; Neuroblastoma; Phosphodiesterase Inhibitors; Piperazines; Pteridines; Purinones; Tumor Cells, Cultured | 2001 |
7-Benzylamino-6-chloro-2-piperazino-4-pyrrolidino-pteridine, a potent inhibitor of cAMP-specific phosphodiesterase, enhancing nuclear protein binding to the CRE consensus sequence in human tumour cells.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Bucladesine; Consensus Sequence; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 4; DNA; Humans; Isoenzymes; Nuclear Proteins; Phosphodiesterase Inhibitors; Piperazines; Pteridines; Tumor Cells, Cultured | 2002 |
Intracellular localization of 7-benzylamino-6-chloro-2-piperazino-4-pyrrolidino-pteridine in membrane structures impeding the inhibition of cytosolic cyclic AMP-specific phosphodiesterase.
Topics: Biological Transport; Cyclic AMP; Humans; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Piperazines; Pteridines; Subcellular Fractions; Tumor Cells, Cultured | 2002 |
The induction of cyclic nucleotide phosphodiesterase 4 gene (PDE4D) impairs memory in a water maze task.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Analysis of Variance; Animals; Corpus Striatum; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Gene Expression Regulation; Hippocampus; Isoenzymes; Male; Maze Learning; Phosphodiesterase Inhibitors; Piperazines; Pteridines; Rats; Rats, Wistar; Retention, Psychology; RNA, Messenger; Rolipram; Second Messenger Systems | 2004 |
Pharmacological inhibition of phosphodiesterase 4 triggers ovulation in follicle-stimulating hormone-primed rats.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Benzamides; Chorionic Gonadotropin; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Fertility; Follicle Stimulating Hormone; Oocytes; Ovulation; Oxazoles; Phosphodiesterase Inhibitors; Piperazines; Pteridines; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, LH | 2005 |
Increase of Intracellular Cyclic AMP by PDE4 Inhibitors Affects HepG2 Cell Cycle Progression and Survival.
Topics: Carcinoma, Hepatocellular; Cell Cycle; Cell Cycle Proteins; Cell Proliferation; Cell Survival; Cyclic AMP; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Liver Neoplasms; Phosphodiesterase 4 Inhibitors; Piperazines; Pteridines; Rolipram | 2017 |