Page last updated: 2024-08-16

pseudohypericin and hyperforin

pseudohypericin has been researched along with hyperforin in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's12 (63.16)29.6817
2010's7 (36.84)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chatterjee, S; Nöldner, M1
Bauer, S; Graubaum, HJ; Roots, I; Störmer, E1
Murch, SJ; Rupasinghe, HP; Saxena, PK1
Berger Büter, K; Bobirnac, I; Lübbert, H; Schaffner, W; Schoeffter, P; Simmen, U; Ullmer, C1
Fiamegos, YC; Gioti, EM; Skalkos, DC; Stalikas, CD1
Bässler, D; Schulz, HU; Schürer, M; Weiser, D1
Schubert-Zsilavecz, M; Wurglics, M1
Exner, M; Gmeiner, BM; Hermann, M; Kapiotis, S; Laggner, H; Mühl, A; Schreier, S1
Bornancin, A; Della Loggia, R; Morazzoni, P; Pace, R; Riva, A; Sosa, S; Tubaro, A1
Birt, DF; Delate, K; Dixon, PM; Hammer, KD; Hillwig, ML; Murphy, PA; Solco, AK; Wurtele, ES1
Cirak, C; Ivanauskas, L; Janulis, V; Radusiene, J3
Hatano, T; Inoue, R; Ito, H; Ochi, M; Onoue, S; Seto, Y; Yamada, S1
Miller, CD; Mortensen, T; Shen, F; Shen, S; Sims, RC; Walsh, MK1
Chimirri, S; Ciriaco, M; De Sarro, G; Esposito, S; Mammì, M; Mazzitello, C; Palleria, C; Patanè, M; Pugliese, M; Russo, E; Scicchitano, F; Upton, R; Whalley, BJ1
Birt, DF; Hammer, KD1
Arakawa, NS; Cardoso, RD; Casagrande, R; Fattori, V; Hohmann, MS; Lopes, NP; Tomaz, JC; Verri, WA1
Carrubba, A; Lazzara, S; Militello, M; Napoli, E; Saia, S1

Reviews

3 review(s) available for pseudohypericin and hyperforin

ArticleYear
Hypericum perforatum: a 'modern' herbal antidepressant: pharmacokinetics of active ingredients.
    Clinical pharmacokinetics, 2006, Volume: 45, Issue:5

    Topics: Animals; Anthracenes; Antidepressive Agents; Bridged Bicyclo Compounds; Clinical Trials as Topic; Depression; Flavonoids; Humans; Hypericum; Perylene; Phloroglucinol; Phytotherapy; Plant Extracts; Terpenes

2006
Hypericum perforatum: pharmacokinetic, mechanism of action, tolerability, and clinical drug-drug interactions.
    Phytotherapy research : PTR, 2014, Volume: 28, Issue:5

    Topics: Anthracenes; Antidepressive Agents; Antiviral Agents; Depression; Herb-Drug Interactions; Humans; Hypericum; Perylene; Phloroglucinol; Plant Extracts; Plants, Medicinal; Terpenes

2014
Evidence for contributions of interactions of constituents to the anti-inflammatory activity of Hypericum perforatum.
    Critical reviews in food science and nutrition, 2014, Volume: 54, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Biflavonoids; Disease Models, Animal; Flavonoids; Humans; Hypericum; Perylene; Phloroglucinol; Plant Extracts; Signal Transduction; Terpenes

2014

Trials

1 trial(s) available for pseudohypericin and hyperforin

ArticleYear
Investigation of pharmacokinetic data of hypericin, pseudohypericin, hyperforin and the flavonoids quercetin and isorhamnetin revealed from single and multiple oral dose studies with a hypericum extract containing tablet in healthy male volunteers.
    Arzneimittel-Forschung, 2005, Volume: 55, Issue:10

    Topics: Adolescent; Adult; Anthracenes; Bridged Bicyclo Compounds; Flavonols; Humans; Hypericum; Male; Middle Aged; Perylene; Phloroglucinol; Plant Extracts; Quercetin; Tablets; Terpenes

2005

Other Studies

15 other study(ies) available for pseudohypericin and hyperforin

ArticleYear
Effects of two different extracts of St. John's wort and some of their constituents on cytochrome P450 activities in rat liver microsomes.
    Pharmacopsychiatry, 2001, Volume: 34 Suppl 1

    Topics: Animals; Anthracenes; Antidepressive Agents; Bridged Bicyclo Compounds; Cytochrome P-450 Enzyme System; Ethanol; Excitatory Amino Acid Antagonists; Female; Hypericum; Liver; Male; Methanol; Microsomes; Perylene; Phenobarbital; Phloroglucinol; Plant Extracts; Quercetin; Rats; Rats, Sprague-Dawley; Sex Factors; Solvents; Terpenes

2001
Determination of hyperforin, hypericin, and pseudohypericin in human plasma using high-performance liquid chromatography analysis with fluorescence and ultraviolet detection.
    Journal of chromatography. B, Biomedical sciences and applications, 2001, Dec-05, Volume: 765, Issue:1

    Topics: Anthracenes; Bridged Bicyclo Compounds; Chromatography, High Pressure Liquid; Humans; Perylene; Phloroglucinol; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Terpenes

2001
An in vitro and hydroponic growing system for hypericin, pseudohypericin, and hyperforin production of St. John's wort (Hypericum perforatum CV new stem).
    Planta medica, 2002, Volume: 68, Issue:12

    Topics: Anthracenes; Bridged Bicyclo Compounds; Culture Techniques; Environment, Controlled; Hydroponics; Hypericum; Perylene; Phloroglucinol; Plant Extracts; Terpenes

2002
Antagonist effect of pseudohypericin at CRF1 receptors.
    European journal of pharmacology, 2003, Jan-05, Volume: 458, Issue:3

    Topics: Animals; Anthracenes; Bridged Bicyclo Compounds; Calcitonin; CHO Cells; Corticotropin-Releasing Hormone; Cricetinae; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Perylene; Phloroglucinol; Receptors, Corticotropin-Releasing Hormone; Terpenes; Transfection

2003
Single-drop liquid-phase microextraction for the determination of hypericin, pseudohypericin and hyperforin in biological fluids by high performance liquid chromatography.
    Journal of chromatography. A, 2005, Nov-04, Volume: 1093, Issue:1-2

    Topics: Anthracenes; Bridged Bicyclo Compounds; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Osmolar Concentration; Perylene; Phloroglucinol; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Terpenes

2005
The main components of St John's Wort inhibit low-density lipoprotein atherogenic modification: a beneficial "side effect" of an OTC antidepressant drug?
    Free radical research, 2007, Volume: 41, Issue:2

    Topics: Anthracenes; Antidepressive Agents; Antioxidants; Atherosclerosis; Bridged Bicyclo Compounds; Cells, Cultured; Chromatography, High Pressure Liquid; Circular Dichroism; Depression; Drug Evaluation, Preclinical; Endothelial Cells; Humans; Hypericum; Lipoproteins, LDL; Malondialdehyde; Mass Spectrometry; Molecular Structure; Nonprescription Drugs; Oxidation-Reduction; Peroxidase; Perylene; Phloroglucinol; Phytotherapy; Protein Binding; Structure-Activity Relationship; Terpenes; Thiobarbituric Acid Reactive Substances; Thromboplastin; Tyrosine; Umbilical Veins

2007
Topical anti-inflammatory activity of extracts and compounds from Hypericum perforatum L.
    The Journal of pharmacy and pharmacology, 2007, Volume: 59, Issue:5

    Topics: Administration, Topical; Animals; Anthracenes; Anti-Inflammatory Agents; Bridged Bicyclo Compounds; Croton Oil; Dose-Response Relationship, Drug; Edema; Flavonoids; Flowers; Hypericum; Inhibitory Concentration 50; Male; Mice; Perylene; Phloroglucinol; Phytotherapy; Plant Extracts; Plants, Medicinal; Terpenes

2007
Inhibition of prostaglandin E(2) production by anti-inflammatory hypericum perforatum extracts and constituents in RAW264.7 Mouse Macrophage Cells.
    Journal of agricultural and food chemistry, 2007, Sep-05, Volume: 55, Issue:18

    Topics: Animals; Anti-Inflammatory Agents; Bridged Bicyclo Compounds; Cell Death; Cells, Cultured; Dinoprostone; Flavonoids; Hypericum; Light; Macrophages; Mice; Perylene; Phloroglucinol; Plant Extracts; Terpenes

2007
Pseudohypericin and hyperforin in Hypericum perforatum from Northern Turkey: variation among populations, plant parts and phenological stages.
    Journal of integrative plant biology, 2008, Volume: 50, Issue:5

    Topics: Bridged Bicyclo Compounds; Climate; Geography; Hypericum; Perylene; Phloroglucinol; Plant Leaves; Plant Stems; Plant Structures; Population Dynamics; Seasons; Terpenes; Turkey

2008
Chemical constituents of Hypericum adenotrichum Spach, an endemic Turkish species.
    Natural product research, 2009, Volume: 23, Issue:13

    Topics: Anthracenes; Bridged Bicyclo Compounds; Chromatography, High Pressure Liquid; Hypericum; Kaempferols; Perylene; Phloroglucinol; Quercetin; Terpenes; Turkey

2009
Secondary metabolites of Hypericum confertum and their possible chemotaxonomic significance.
    Natural product communications, 2010, Volume: 5, Issue:6

    Topics: Anthracenes; Apigenin; Biflavonoids; Bridged Bicyclo Compounds; Chlorogenic Acid; Hypericum; Perylene; Phloroglucinol; Plant Components, Aerial; Quercetin; Rutin; Terpenes

2010
In vitro photochemical and phototoxicological characterization of major constituents in St. John's Wort (Hypericum perforatum) extracts.
    Phytochemistry, 2011, Volume: 72, Issue:14-15

    Topics: Anthracenes; Antidepressive Agents; Biological Products; Dermatitis, Phototoxic; DNA Damage; Enzyme Inhibitors; Hypericum; Light; Lipid Peroxidation; Perylene; Phloroglucinol; Plant Extracts; Reactive Oxygen Species; Terpenes

2011
Investigating the effectiveness of St John's wort herb as an antimicrobial agent against mycobacteria.
    Phytotherapy research : PTR, 2012, Volume: 26, Issue:9

    Topics: Anthracenes; Anti-Bacterial Agents; Hypericum; Microbial Sensitivity Tests; Microscopy, Electron, Scanning; Mycobacterium; Perylene; Phloroglucinol; Plant Extracts; Terpenes

2012
Hypericum perforatum Reduces Paracetamol-Induced Hepatotoxicity and Lethality in Mice by Modulating Inflammation and Oxidative Stress.
    Phytotherapy research : PTR, 2015, Volume: 29, Issue:7

    Topics: Acetaminophen; Alanine Transaminase; Animals; Anthracenes; Anti-Inflammatory Agents; Antioxidants; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Glutathione; Hypericum; Inflammation; Male; Mice; Oxidative Stress; Perylene; Phloroglucinol; Plant Extracts; Plants, Medicinal; Quercetin; Rutin; Terpenes; Tumor Necrosis Factor-alpha

2015
Arbuscular mycorrhizal fungi altered the hypericin, pseudohypericin, and hyperforin content in flowers of Hypericum perforatum grown under contrasting P availability in a highly organic substrate.
    Mycorrhiza, 2017, Volume: 27, Issue:4

    Topics: Anthracenes; Flowers; Hypericum; Mycorrhizae; Perylene; Phloroglucinol; Phosphorus; Plant Extracts; Terpenes

2017