prunetin has been researched along with naringenin* in 1 studies
1 other study(ies) available for prunetin and naringenin
Article | Year |
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Semisynthesis of prunetin, a bioactive O-methylated isoflavone from naringenin, by the sequential deacetylation of chalcone intermediates and oxidative rearrangement.
Prunetin (4',5-dihydroxy-7-methoxyisoflavone) was semisynthesized in 8 steps from readily available naringenin in 26% total yield. The key reaction was chemoenzymatic sequential deacetylation to 6'-acetoxy-2',4″-dihydroxy-4'-methoxychalcone, the in situ-formed precursor for thallium(III) nitrate-mediated oxidative rearrangement. Topics: Acetylation; Chalcone; Chemistry Techniques, Synthetic; Flavanones; Isoflavones; Methylation; Oxidation-Reduction; Oxygen | 2021 |