Compounds > prulifloxacin
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prulifloxacin and ciprofloxacin

prulifloxacin has been researched along with ciprofloxacin in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (18.75)18.2507
2000's12 (75.00)29.6817
2010's1 (6.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kazuno, K; Kise, M; Kitano, M; Matsuda, M; Matsuoka, M; Ozaki, M; Segawa, J; Shirahase, I; Tomii, Y1
Kimura, K; Kise, M; Kitano, M; Matsuda, M; Nishino, T; Otsuki, M; Ozaki, M; Segawa, J; Shibata, K; Tomii, Y1
Mitsuhashi, S; Yoshida, T1
Dionisio, P; Grassi, C; Rosignoli, MT; Salvatori, E1
Araake, M; Hara, T; Nishino, T; Watabe, H1
Araake, M; Hara, T; Nishino, T; Shimizu, M; Tabata, M; Watabe, H1
Araake, M; Maebashi, K; Tani, M; Watabe, H1
Ciottoli, GB; Crumb, WJ; Durando, L; Lacroix, P1
Keam, SJ; Perry, CM1
Carmignani, G; De Rose, AF; Dionisio, P; Olivieri, L; Rosignoli, MT; Salvatori, E1
Marchese, A; Roveta, S; Schito, AM; Schito, GC1
Gualco, L; Marchese, A; Schito, AM; Schito, GC1
Esposito, S; Ianniello, F; Leone, S; Noviello, S1
Cagini, C; Pellegrino, RM; Segoloni, F1
Kim, J; Ohtani, H; Sawada, Y; Tsujimoto, M1
De Vecchi, E; Drago, L; Mattina, R; Nicola, L1

Trials

3 trial(s) available for prulifloxacin and ciprofloxacin

ArticleYear
Randomized, double-blind study of prulifloxacin versus ciprofloxacin in patients with acute exacerbations of chronic bronchitis.
    Respiration; international review of thoracic diseases, 2002, Volume: 69, Issue:3

    Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Bronchitis; Chronic Disease; Ciprofloxacin; Dioxolanes; Double-Blind Method; Female; Fluoroquinolones; Humans; Male; Middle Aged; Piperazines; Quinolones; Treatment Outcome

2002
Prulifloxacin.
    Drugs, 2004, Volume: 64, Issue:19

    Topics: Administration, Oral; Amoxicillin; Animals; Anti-Bacterial Agents; Bronchitis, Chronic; Ciprofloxacin; Clavulanic Acid; Dioxolanes; Drug Evaluation, Preclinical; Drug Therapy, Combination; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Half-Life; Humans; Italy; Molecular Structure; New Zealand; Pefloxacin; Piperazines; Prodrugs; Quinolones; Urinary Tract Infections

2004
Prulifloxacin versus ciprofloxacin in the treatment of adults with complicated urinary tract infections.
    Urologia internationalis, 2005, Volume: 74, Issue:4

    Topics: Adult; Aged; Anti-Infective Agents; Ciprofloxacin; Dioxolanes; Double-Blind Method; Female; Fluoroquinolones; Humans; Male; Middle Aged; Piperazines; Quinolones; Treatment Outcome; Urinary Tract Infections

2005

Other Studies

13 other study(ies) available for prulifloxacin and ciprofloxacin

ArticleYear
Studies on pyridonecarboxylic acids. 1. Synthesis and antibacterial evaluation of 7-substituted-6-halo-4-oxo-4H-[1,3]thiazeto[3,2-a]quinoline-3- carboxylic acids.
    Journal of medicinal chemistry, 1992, Dec-11, Volume: 35, Issue:25

    Topics: Administration, Oral; Animals; Anti-Infective Agents; Carboxylic Acids; Escherichia coli Infections; Fluoroquinolones; Male; Mice; Microbial Sensitivity Tests; Pseudomonas Infections; Quinolones; Structure-Activity Relationship

1992
In vivo evaluation of NM441, a new thiazeto-quinoline derivative.
    Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:12

    Topics: Administration, Oral; Animals; Anti-Infective Agents; Ciprofloxacin; Dioxolanes; Dogs; Drug Evaluation, Preclinical; Enoxacin; Female; Fluoroquinolones; Male; Mice; Microbial Sensitivity Tests; Ofloxacin; Piperazines; Prodrugs; Quinolones; Respiratory Tract Infections; Streptococcal Infections; Urinary Tract Infections

1991
Antibacterial activity of NM394, the active form of prodrug NM441, a new quinolone.
    Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:4

    Topics: Anti-Infective Agents; Bacteria; Ciprofloxacin; Dioxolanes; Enoxacin; Fluoroquinolones; Microbial Sensitivity Tests; Mutation; Naphthyridines; Ofloxacin; Piperazines; Quinolones; Topoisomerase II Inhibitors

1993
[In vitro antibacterial activity of prulifloxacin, a new oral fluoroquinolone].
    The Japanese journal of antibiotics, 2002, Volume: 55, Issue:6

    Topics: Anti-Infective Agents; Ciprofloxacin; Dioxolanes; Dosage Forms; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Fleroxacin; Fluoroquinolones; Gatifloxacin; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Levofloxacin; Naphthyridines; Ofloxacin; Piperazines; Prodrugs; Quinolones

2002
[In vitro short-term bactericidal activity and accumulation of NM394, the active metabolite of prulifloxacin, for Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa: comparison with ciprofloxacin, levofloxacin, and gatifloxacin].
    The Japanese journal of antibiotics, 2002, Volume: 55, Issue:6

    Topics: Anti-Infective Agents; Ciprofloxacin; Dioxolanes; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Escherichia coli; Fluoroquinolones; Gatifloxacin; Levofloxacin; Ofloxacin; Piperazines; Prodrugs; Pseudomonas aeruginosa; Quinolones; Staphylococcus aureus; Time Factors

2002
[Inhibitory activity of NM394, the active form of prodrug prulifloxacin against type II topoisomerase from Pseudomonas aeruginosa].
    The Japanese journal of antibiotics, 2002, Volume: 55, Issue:6

    Topics: Anti-Infective Agents; Ciprofloxacin; Dioxolanes; DNA Topoisomerase IV; Dose-Response Relationship, Drug; Fluoroquinolones; Gatifloxacin; Levofloxacin; Ofloxacin; Piperazines; Prodrugs; Pseudomonas aeruginosa; Quinolones; Topoisomerase II Inhibitors

2002
Prulifloxacin: in vitro (HERG current) and in vivo (conscious dog) assessment of cardiac risk.
    European journal of pharmacology, 2003, Sep-05, Volume: 477, Issue:1

    Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Aza Compounds; Cell Line; Ciprofloxacin; Dioxolanes; DNA-Binding Proteins; Dogs; Fluoroquinolones; In Vitro Techniques; Moxifloxacin; Patch-Clamp Techniques; Piperazines; Potassium Channel Blockers; Quinolines; Quinolones; Telemetry; Trans-Activators; Transcriptional Regulator ERG

2003
Microbiological rationale for the utilisation of prulifloxacin, a new fluoroquinolone, in the eradication of serious infections caused by Pseudomonas aeruginosa.
    International journal of antimicrobial agents, 2005, Volume: 26, Issue:5

    Topics: Anti-Bacterial Agents; Aza Compounds; Ciprofloxacin; Cystic Fibrosis; Dioxolanes; Drug Resistance, Bacterial; Fluoroquinolones; Humans; In Vitro Techniques; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Opportunistic Infections; Piperazines; Pseudomonas aeruginosa; Pseudomonas Infections; Quinolines; Quinolones

2005
In vitro activity of prulifloxacin against Escherichia coli isolated from urinary tract infections and the biological cost of prulifloxacin resistance.
    International journal of antimicrobial agents, 2007, Volume: 29, Issue:6

    Topics: Anti-Infective Agents, Urinary; Bacterial Adhesion; Ciprofloxacin; Dioxolanes; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Fluoroquinolones; Hemolysin Proteins; Humans; In Vitro Techniques; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Piperazines; Quinolones; Ultraviolet Rays; Urinary Tract Infections

2007
[In vitro activity of prulifloxacin, levofloxacin and ciprofloxacin against urinary pathogens].
    Le infezioni in medicina, 2006, Volume: 14, Issue:1

    Topics: Anti-Bacterial Agents; Ciprofloxacin; Dioxolanes; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; In Vitro Techniques; Levofloxacin; Methicillin Resistance; Microbial Sensitivity Tests; Ofloxacin; Piperazines; Quinolones; Staphylococcus aureus; Urinary Tract Infections

2006
Simultaneous determination of Ciprofloxacin and the active metabolite of Prulifloxacin in aqueous human humor by high-performance liquid chromatography.
    Journal of pharmaceutical and biomedical analysis, 2008, Jul-15, Volume: 47, Issue:3

    Topics: Aged; Aged, 80 and over; Aqueous Humor; Calibration; Chromatography, High Pressure Liquid; Ciprofloxacin; Dioxolanes; Female; Fluoroquinolones; Humans; Male; Middle Aged; Piperazines; Reproducibility of Results

2008
Quantitative comparison of the convulsive activity of combinations of twelve fluoroquinolones with five nonsteroidal antiinflammatory agents.
    Drug metabolism and pharmacokinetics, 2009, Volume: 24, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Ciprofloxacin; Diclofenac; Dioxolanes; Drug Combinations; Drug Interactions; Enoxacin; Fleroxacin; Fluoroquinolones; Gatifloxacin; Levofloxacin; Male; Mice; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Phenylacetates; Piperazines; Receptors, GABA-A; Seizures

2009
In vitro selection of resistance in Escherichia coli and Klebsiella spp. at in vivo fluoroquinolone concentrations.
    BMC microbiology, 2010, Apr-21, Volume: 10

    Topics: Anti-Bacterial Agents; Bacterial Proteins; Ciprofloxacin; Dioxolanes; DNA Gyrase; DNA Mutational Analysis; DNA Topoisomerase IV; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Fluoroquinolones; Humans; Klebsiella; Klebsiella Infections; Levofloxacin; Microbial Sensitivity Tests; Mutation; Ofloxacin; Piperazines; Respiratory Tract Infections; Selection, Genetic; Urinary Tract Infections

2010