proxyphylline has been researched along with theophylline in 52 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 25 (48.08) | 18.7374 |
| 1990's | 13 (25.00) | 18.2507 |
| 2000's | 5 (9.62) | 29.6817 |
| 2010's | 7 (13.46) | 24.3611 |
| 2020's | 2 (3.85) | 2.80 |
| Authors | Studies |
|---|---|
| Brufani, M; Cavallaro, RA; Filocamo, L; Galione, A; Galuppi, A; Genazzani, AA | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Johno, I; Kitazawa, S; Minouchi, T; Okada, J | 1 |
| Katano, Y; Nakagawa, Y; Nakazawa, M; Takeda, K; Tsukada, T | 1 |
| Mizusawa, H; Sakai, K; Sakamoto, K; Sakanashi, M; Takenaka, F; Takeo, S | 1 |
| Kanto, J; Katevuo, K; Kleimola, T | 1 |
| Arbin, A; Berg, M; Boréus, LO | 1 |
| Apichartpichean, R; Hasegawa, T; Muraoka, I; Nabeshima, T; Nadai, M; Takagi, K | 1 |
| Brandis, M; Burghard, R; Gordjani, N; Gundert-Remy, U; Leititis, JU; Püschel, CH | 1 |
| Doelker, E; Gander, B; Gurny, R; Peppas, NA | 1 |
| Aasen, AJ; Rasmussen, KE; Ruud-Christensen, M; Salvesen, B | 1 |
| Hartmann, V; Jörres, R; Magnussen, H | 1 |
| Jörres, R; Litt, M; Magnussen, H; Reuss, G; Stutz, P | 1 |
| Kalla, M; Reinhardt, D; Richter, O | 1 |
| Svedmyr, K | 1 |
| Bjerve, KS; Selvig, K | 1 |
| Holzmann, S; Kukovetz, WR; Pöch, G | 1 |
| Mirsching, G | 1 |
| Mosbech, H; Paulsen, H; Søborg, M | 1 |
| Aasen, AJ; Ruud-Christensen, M; Selvig, K | 1 |
| Eggs, B; Follath, F; Wenk, M | 1 |
| Bogaert, MG | 1 |
| Madsen, L; Rasmussen, FV; Waldorff, S | 1 |
| Garcia, I; Segura, J; Tarrus, E | 1 |
| Allonen, H; Kanto, J; Kulmala, T; Mäntylä, R; Tala, E | 1 |
| Bracher, P; Brändli, O | 1 |
| Selvig, K | 1 |
| Leeuwin, RS; Ottenhof, M; Ufkes, JG; Zeegers, A; Zuidema, J | 1 |
| Förster, OB; Geisler, LS; Rohner, HG; Thiel, H | 1 |
| Graham, NB; McNeill, ME | 4 |
| Badiger, MV; Graham, NB; McNeill, ME | 1 |
| Khare, AR; Peppas, NA | 1 |
| Bourret, E; Brossard, C; Duclos, R | 1 |
| Peppas, NA; Scott, RA | 1 |
| Lowman, AM; Peppas, NA | 1 |
| Bourret, E; Brossard, C; Duclos, R; Ratsimbazafy, V | 1 |
| Blanco, M; Valverde, I | 1 |
| Coello, J; Iturriaga, H; Maspoch, S; Porcel, M | 1 |
| Brazel, CS; Wu, L | 2 |
| Górska, D; Korzycka, L | 1 |
| Papadokostaki, KG; Soulas, DN | 1 |
| Papadokostaki, KG; Sanopoulou, M; Soulas, DN | 1 |
| Bossé, Y | 1 |
| Borowiecki, P; Dudzik, A; Paprocki, D; Plenkiewicz, J | 1 |
| Borowiecki, P; Bretner, M; Gizińska, M; Koronkiewicz, M; Staniszewska, M; Wińska, P | 1 |
| Brandel, C; Cartigny, Y; Coquerel, G; Harfouche, LC; Petit, S; Ter Horst, JH | 1 |
| Baran, J; Borowiecki, P; Gizińska, M; Kazek, M; Koronkiewicz, M; Kuryk, Ł; Milner-Krawczyk, M; Staniszewska, A; Staniszewska, M | 1 |
| Borowiecki, P; Kroutil, W; Reiter, T; Rudzka, A | 1 |
1 review(s) available for proxyphylline and theophylline
| Article | Year |
|---|---|
Endocrine regulation of airway contractility is overlooked.
Topics: Adaptation, Physiological; Adiponectin; Androgens; Animals; Asthma; Bronchodilator Agents; Dehydroepiandrosterone; Epinephrine; Estrogens; Female; Fibrin; Gastrin-Releasing Peptide; Gastrointestinal Hormones; Glucocorticoids; Humans; Insulin; Leptin; Lung; Male; Muscle Contraction; Muscle, Smooth; Natriuretic Peptides; Progesterone; Respiratory Physiological Phenomena; Respiratory System; Theophylline; Thyroid Hormones; Urokinase-Type Plasminogen Activator | 2014 |
7 trial(s) available for proxyphylline and theophylline
| Article | Year |
|---|---|
Bronchodilator effect of theophylline preparations and aerosol fenoterol in stable asthma.
Topics: Airway Resistance; Aminophylline; Asthma; Clinical Trials as Topic; Double-Blind Method; Drug Synergism; Dyphylline; Fenoterol; Forced Expiratory Volume; Humans; Theophylline | 1986 |
[Comparison of the bronchodilator and protective effect of methylxanthines].
Topics: Adolescent; Adult; Aminophylline; Asthma; Asthma, Exercise-Induced; Bronchodilator Agents; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Dyphylline; Ethylenediamines; Female; Humans; Male; Middle Aged; Random Allocation; Theophylline; Xanthines | 1986 |
[Pharmacokinetics and pharmacodynamics of proxyphylline in asthmatic children].
Topics: Administration, Oral; Adolescent; Aminophylline; Asthma; Bronchial Provocation Tests; Child; Delayed-Action Preparations; Dose-Response Relationship, Drug; Female; Half-Life; Humans; Injections, Intravenous; Kinetics; Lung Volume Measurements; Male; Metabolic Clearance Rate; Theophylline | 1985 |
[Asthma therapy. Clinical trial of 2 proxyphylline/ephedrine combinations with immediate and long-term effect].
Topics: Adult; Aminophylline; Asthma; Clinical Trials as Topic; Delayed-Action Preparations; Drug Combinations; Ephedrine; Female; Humans; Male; Middle Aged; Theophylline | 1983 |
Controlled-release theophylline and proxyphylline in asthmatics: a comparative study.
Topics: Adult; Aged; Aminophylline; Asthma; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method; Forced Expiratory Volume; Humans; Middle Aged; Random Allocation; Theophylline | 1984 |
Interaction between proxyphylline and salbutamol.
Topics: Adolescent; Adult; Albuterol; Aminophylline; Animals; Asthma; Bronchodilator Agents; Clinical Trials as Topic; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Female; Guinea Pigs; Humans; Male; Middle Aged; Random Allocation; Theophylline | 1981 |
[Pharmacokinetic and clinical effectiveness of rectally administered theophylline].
Topics: Adult; Aged; Aminophylline; Blood Pressure; Double-Blind Method; Drug Combinations; Dyphylline; Humans; Lung; Lung Diseases, Obstructive; Middle Aged; Pulse; Theophylline | 1982 |
44 other study(ies) available for proxyphylline and theophylline
| Article | Year |
|---|---|
Potentiation of cADPR-induced Ca(2+)-release by methylxanthine analogues.
Topics: Adenosine Diphosphate Ribose; Animals; Caffeine; Calcium; Cyclic ADP-Ribose; Drug Evaluation, Preclinical; In Vitro Techniques; Ovum; Ryanodine Receptor Calcium Release Channel; Sea Urchins; Structure-Activity Relationship; Xanthines | 1999 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Interpretation of dissolution rate data from in vitro testing of compressed tablets.
Topics: Aspirin; Caffeine; Chemistry, Pharmaceutical; Hardness; Kinetics; Models, Chemical; Solubility; Surface Properties; Tablets; Theophylline; Time Factors | 1977 |
Effects of aminophylline, proxyphylline and a proxyphylline-Melilotus extract-rutin mixture (theoesberiven) on the heart and the coronary circulation.
Topics: Adenosine; Aminophylline; Animals; Blood Volume; Cardiac Output; Coronary Circulation; Coumarins; Dogs; Dose-Response Relationship, Drug; Drug Combinations; Female; Guinea Pigs; Heart; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Myocardium; Oxygen; Oxygen Consumption; Plant Extracts; Rutin; Stimulation, Chemical; Theophylline | 1977 |
[Effects of Theo-Esberiven on the coronary circulation and myocardial metabolisms in dogs (author's transl)].
Topics: Action Potentials; Animals; Blood Flow Velocity; Blood Pressure; Coronary Circulation; Dogs; Dose-Response Relationship, Drug; Drug Combinations; Heart Rate; In Vitro Techniques; Myocardial Contraction; Myocardium; Oxygen Consumption; Plant Extracts; Rutin; Theophylline | 1978 |
The effect of intravenously administered proxyphylline and Baralgin on the contraction of the human gallbladder.
Topics: Adult; Benzophenones; Drug Therapy, Combination; Female; Gallbladder Diseases; Humans; Injections, Intravenous; Male; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Theophylline; Time Factors | 1978 |
Determination of proxyphylline and dyphylline in capillary blood samples by means of electron capture gas chromatography.
Topics: Chromatography, Gas; Humans; Theophylline | 1976 |
Pharmacokinetic characteristics of N7-substituted theophylline derivatives and their interaction with quinolone in rats.
Topics: Aminophylline; Animals; Blood Proteins; Chemical Phenomena; Chemistry, Physical; Chromatography, High Pressure Liquid; Drug Interactions; Dyphylline; Enoxacin; Kidney Tubules; Male; Protein Binding; Quinolones; Rats; Rats, Inbred Strains; Theophylline | 1991 |
Acute intoxication with theophylline, proxyphylline and diprophylline in a 3-month-old infant after rectal application: pharmacokinetic data under hemoperfusion.
Topics: Administration, Rectal; Aminophylline; Drug Combinations; Dyphylline; Hemoperfusion; Humans; Infant; Male; Theophylline | 1990 |
Effect of polymeric network structure on drug release from cross-linked poly(vinyl alcohol) micromatrices.
Topics: Aminophylline; Chemistry, Pharmaceutical; Cross-Linking Reagents; Delayed-Action Preparations; Diffusion; Glutaral; Pharmaceutical Preparations; Polyvinyl Alcohol; Sulfuric Acids; Theophylline | 1989 |
High-performance liquid chromatographic determination of (R)-and (S)-proxyphylline in human plasma.
Topics: Aminophylline; Camphor; Chromatography, High Pressure Liquid; Humans; Solvents; Stereoisomerism; Theophylline | 1989 |
beta 2-Adrenoceptor stimulants and theophylline in asthma therapy.
Topics: Administration, Oral; Adrenergic beta-Agonists; Aerosols; Albuterol; Aminophylline; Asthma; Bronchodilator Agents; Drug Therapy, Combination; Ephedrine; Heart Rate; Humans; Respiration; Theophylline | 1981 |
Inhibition of human lung cyclic nucleotide phosphodiesterases by proxyphylline, theophylline and their metabolites.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Aminophylline; Cytosol; Humans; In Vitro Techniques; Kinetics; Lung; Theophylline | 1982 |
Overadditive synergism between theophylline, diprophylline and proxyphylline in tracheal smooth muscle relaxation.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Airway Resistance; Aminophylline; Animals; Cattle; Drug Synergism; Dyphylline; Guinea Pigs; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth; Myocardial Contraction; Theophylline; Trachea | 1983 |
Optical resolution, absolute configuration, and activity of the enantiomers of proxyphylline.
Topics: Aminophylline; Indicators and Reagents; Magnetic Resonance Spectroscopy; Molecular Conformation; Optical Rotation; Stereoisomerism; Structure-Activity Relationship; Theophylline | 1983 |
Simultaneous determination of diprophylline, proxyphylline and theophylline in serum by reversed-phase high-performance liquid chromatography.
Topics: Adult; Aminophylline; Chromatography, High Pressure Liquid; Dyphylline; Female; Humans; Hydrogen-Ion Concentration; Kinetics; Male; Specimen Handling; Theophylline | 1983 |
Non-linear kinetics of theophylline.
Topics: Aminophylline; Humans; Kinetics; Theophylline | 1984 |
Pharmacokinetics and bronchodilatory effect of proxyphylline and theophylline.
Topics: Administration, Oral; Adolescent; Adult; Airway Obstruction; Aminophylline; Asthma; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Infusions, Parenteral; Kinetics; Male; Theophylline | 1984 |
Human metabolism of 7-substituted theophyllines: N3-demethylation and lack of oxidation of proxyphylline.
Topics: Aminophylline; Animals; Biotransformation; Dealkylation; Guinea Pigs; Humans; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth; Oxidation-Reduction; Theophylline; Xanthine Oxidase | 1981 |
Pharmacokinetics of proxyphylline in adults after intravenous and oral administration.
Topics: Administration, Oral; Adult; Aminophylline; Biological Availability; Female; Humans; Injections, Intravenous; Kinetics; Male; Theophylline | 1981 |
Efficacy of theophylline and its N-7-substituted derivatives in experimentally induced bronchial asthma in the guinea-pig.
Topics: Aminophylline; Animals; Asthma; Dyphylline; Female; Guinea Pigs; In Vitro Techniques; Theophylline; Xanthines | 1981 |
[Effectiveness of proxyphylline in chronic obstructive pulmonary disease (author's transl)].
Topics: Adult; Aged; Aminophylline; Bronchospirometry; Humans; Lung Diseases, Obstructive; Male; Middle Aged; Plethysmography, Whole Body; Theophylline; Time Factors; Tremor | 1980 |
Properties controlling the diffusion and release of water-soluble solutes from poly(ethylene oxide) hydrogels. 2. Dispersion in an initially dry slab.
Topics: Albuterol; Aminophylline; Aspirin; Biocompatible Materials; Diffusion; Dinoprostone; Drug Carriers; Kinetics; Lithium Chloride; Mathematics; Models, Theoretical; Polyethylene Glycols; Solubility; Surface Properties; Theophylline | 1993 |
Porogens in the preparation of microporous hydrogels based on poly(ethylene oxides).
Topics: Aminophylline; Biocompatible Materials; Calorimetry, Differential Scanning; Delayed-Action Preparations; Diffusion; Gels; Magnetic Resonance Spectroscopy; Molecular Weight; Polyethylene Glycols; Polyurethanes; Porosity; Spectrophotometry, Ultraviolet; Theophylline; Vitamin B 12 | 1993 |
Release behavior of bioactive agents from pH-sensitive hydrogels.
Topics: Acrylic Resins; Aminophylline; Biocompatible Materials; Diffusion; Drug Carriers; Drug Delivery Systems; Gels; Hydrogen-Ion Concentration; Methacrylates; Osmolar Concentration; Oxprenolol; Polyhydroxyethyl Methacrylate; Polymers; Theophylline | 1993 |
Properties controlling the diffusion and release of water-soluble solutes from poly(ethylene oxide) hydrogels. 1. Polymer composition.
Topics: Aminophylline; Biocompatible Materials; Caffeine; Diffusion; Drug Carriers; Drug Delivery Systems; Gels; Models, Chemical; Morphine; Polyethylene Glycols; Polyurethanes; Solubility; Theophylline; Water | 1993 |
Properties controlling the diffusion and release of water-soluble solutes from poly(ethylene oxide) hydrogels: 3. Device geometry.
Topics: Aminophylline; Asthma; Cross-Linking Reagents; Diffusion; Drug Delivery Systems; Gels; Half-Life; Mathematics; Particle Size; Polyethylene Glycols; Solubility; Surface Properties; Theophylline; Urethane; Water | 1996 |
Properties controlling the diffusion and release of water-soluble solutes from poly(ethylene oxide) hydrogels. 4. Extended constant rate release from partly-coated spheres.
Topics: Aminophylline; Asthma; Delayed-Action Preparations; Diffusion; Drug Delivery Systems; Gels; Hydrogen-Ion Concentration; Osmolar Concentration; Particle Size; Polyethylene Glycols; Rubber; Solubility; Surface Properties; Temperature; Theophylline; Water | 1996 |
Rheology of polyol behenates and drug release from matrix monolithic capsules.
Topics: Aminophylline; Capsules; Fatty Acids; Particle Size; Polymers; Solubility; Suspensions; Theophylline; Viscosity | 1999 |
Highly crosslinked, PEG-containing copolymers for sustained solute delivery.
Topics: Acrylates; Aminophylline; Biocompatible Materials; Drug Carriers; Kinetics; Polyethylene Glycols; Structure-Activity Relationship; Theophylline | 1999 |
Solute transport analysis in pH-responsive, complexing hydrogels of poly(methacrylic acid-g-ethylene glycol).
Topics: Aminophylline; Biocompatible Materials; Delayed-Action Preparations; Dextrans; Diffusion; Drug Delivery Systems; Fluorescein-5-isothiocyanate; Hydrogels; Hydrogen-Ion Concentration; In Vitro Techniques; Materials Testing; Molecular Weight; Polyethylene Glycols; Polymethacrylic Acids; Solutions; Theophylline; Vitamin B 12 | 1999 |
Rheological behavior of drug suspensions in Gelucire mixtures and proxyphylline release from matrix hard gelatin capsules.
Topics: Aminophylline; Capsules; Chemistry, Pharmaceutical; Delayed-Action Preparations; Diffusion; Excipients; Fats; Gelatin; Lipids; Oils; Rheology; Surface Properties; Suspensions; Theophylline; Viscosity | 1999 |
Application of micellar electrokinetic chromatography to the quality control of a pharmaceutical preparation containing three bronchodilators.
Topics: Aminophylline; Bronchodilator Agents; Chromatography, Micellar Electrokinetic Capillary; Drug Combinations; Drug Compounding; Dyphylline; Linear Models; Methods; Quality Control; Reproducibility of Results; Sensitivity and Specificity; Theophylline | 2002 |
Kinetic-spectrophotometric determination of theophylline, dyphylline, and proxyphylline by use of partial least-squares regression.
Topics: Aminophylline; Bronchodilator Agents; Chromatography, High Pressure Liquid; Dyphylline; Hydrogen-Ion Concentration; Kinetics; Least-Squares Analysis; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Theophylline | 2002 |
Surface crosslinking for delayed release of proxyphylline from PHEMA hydrogels.
Topics: Aminophylline; Bronchodilator Agents; Chemistry, Pharmaceutical; Cross-Linking Reagents; Delayed-Action Preparations; Hydrogels; Molecular Weight; Polyhydroxyethyl Methacrylate; Solutions; Surface Properties; Theophylline; Water | 2008 |
Modifying the release of proxyphylline from PVA hydrogels using surface crosslinking.
Topics: Absorption; Aminophylline; Cross-Linking Reagents; Delayed-Action Preparations; Excipients; Glutaral; Hydrogels; Kinetics; Microscopy, Confocal; Spectrophotometry, Ultraviolet; Theophylline | 2008 |
Synthesis, pharmacological activity and nitric oxide generation by nitrate derivatives of theophylline.
Topics: Aminophylline; Animals; Blood Pressure; Dyphylline; Hypertension; Male; Nitrates; Nitric Oxide; Nitric Oxide Donors; Phosphodiesterase Inhibitors; Rats; Rats, Inbred SHR; Theophylline | 2008 |
Regulation of proxyphylline's release from silicone rubber matrices by the use of osmotically active excipients and a multi-layer system.
Topics: Delayed-Action Preparations; Drug Carriers; Excipients; Kinetics; Microscopy, Electron, Scanning; Osmosis; Particle Size; Salts; Silicone Elastomers; Solubility; Technology, Pharmaceutical; Theophylline | 2011 |
Proxyphylline release kinetics from symmetrical three-layer silicone rubber matrices: effect of different excipients in the outer rate-controlling layers.
Topics: Absorption; Algorithms; Chemistry, Pharmaceutical; Delayed-Action Preparations; Dimethylpolysiloxanes; Drug Design; Excipients; Kinetics; Methylcellulose; Microscopy, Electron, Scanning; Osmolar Concentration; Permeability; Polyethylene Glycols; Silicone Elastomers; Sodium Chloride; Solubility; Theophylline; Water | 2012 |
Chemoenzymatic Synthesis of Proxyphylline Enantiomers.
Topics: Acetonitriles; Candida; Catalysis; Enzymes, Immobilized; Esters; Ethanol; Fungal Proteins; Kinetics; Lipase; Stereoisomerism; Theophylline | 2016 |
Synthesis of novel proxyphylline derivatives with dual Anti-Candida albicans and anticancer activity.
Topics: Animals; Antifungal Agents; Antineoplastic Agents; Biofilms; Candida albicans; Cell Proliferation; Chlorocebus aethiops; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; MCF-7 Cells; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; T-Lymphocytes; Theophylline; Vero Cells | 2018 |
Enabling Direct Preferential Crystallization in a Stable Racemic Compound System.
Topics: Butanols; Crystallization; Crystallography, X-Ray; Dyphylline; Solubility; Solutions; Solvents; Stereoisomerism; Theophylline; X-Ray Diffraction | 2019 |
Antifungal polybrominated proxyphylline derivative induces Candida albicans calcineurin stress response in Galleria mellonella.
Topics: Animals; Antifungal Agents; Apoptosis; Aspartic Acid Endopeptidases; Biofilms; Calcineurin; Calcineurin Inhibitors; Candida albicans; Chlorocebus aethiops; Fungal Proteins; Larva; Microbial Sensitivity Tests; Molecular Docking Simulation; Moths; Protein Binding; Theophylline; Vero Cells | 2020 |
Biocatalytic hydrogen-transfer to access enantiomerically pure proxyphylline, xanthinol, and diprophylline.
Topics: Biocatalysis; Chlorohydrins; Dyphylline; Escherichia coli; Hydrogen; Stereoisomerism; Theophylline | 2022 |