proximicin-b and furan

proximicin-b has been researched along with furan* in 2 studies

Other Studies

2 other study(ies) available for proximicin-b and furan

Article	Year
Total synthesis of proximicin A-C and synthesis of new furan-based DNA binding agents. Organic letters, 2009, Jul-02, Volume: 11, Issue:13 The total synthesis of the natural occurring polyamides proximicin A-C (3-5) has been accomplished. A short and efficient synthesis of a thus far unknown 4-amino-2-furan carboxylic acid was developed. Furthermore, this unique heterocyclic gamma-amino-acid was used for the synthesis of a new class of AT-selective DNA-binding agents derived from the natural products combining structural features of the proximicins with those from the known DNA-binding natural products netropsin (1) and distamycin (2). Topics: Amino Acids; Distamycins; DNA; Furans; Molecular Structure; Netropsin; Nylons	2009
Proximicins A, B, and C-antitumor furan analogues of netropsin from the marine actinomycete Verrucosispora induce upregulation of p53 and the cyclin kinase inhibitor p21. Angewandte Chemie (International ed. in English), 2008, Volume: 47, Issue:17 Topics: Actinobacteria; Antineoplastic Agents; Cyclin-Dependent Kinase Inhibitor p21; Furans; Molecular Structure; Netropsin; Tumor Suppressor Protein p53; Up-Regulation	2008

Article

Year

Total synthesis of proximicin A-C and synthesis of new furan-based DNA binding agents.

Organic letters, 2009, Jul-02, Volume: 11, Issue:13

The total synthesis of the natural occurring polyamides proximicin A-C (3-5) has been accomplished. A short and efficient synthesis of a thus far unknown 4-amino-2-furan carboxylic acid was developed. Furthermore, this unique heterocyclic gamma-amino-acid was used for the synthesis of a new class of AT-selective DNA-binding agents derived from the natural products combining structural features of the proximicins with those from the known DNA-binding natural products netropsin (1) and distamycin (2).

Topics: Amino Acids; Distamycins; DNA; Furans; Molecular Structure; Netropsin; Nylons

2009

Proximicins A, B, and C-antitumor furan analogues of netropsin from the marine actinomycete Verrucosispora induce upregulation of p53 and the cyclin kinase inhibitor p21.

Angewandte Chemie (International ed. in English), 2008, Volume: 47, Issue:17

Topics: Actinobacteria; Antineoplastic Agents; Cyclin-Dependent Kinase Inhibitor p21; Furans; Molecular Structure; Netropsin; Tumor Suppressor Protein p53; Up-Regulation

2008