Page last updated: 2024-09-03

protoporphyrinogen and heme

protoporphyrinogen has been researched along with heme in 22 studies

Compound Research Comparison

Studies
(protoporphyrinogen)
Trials
(protoporphyrinogen)
Recent Studies (post-2010)
(protoporphyrinogen)
Studies
(heme)
Trials
(heme)
Recent Studies (post-2010) (heme)
5311419,0861154,781

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19907 (31.82)18.7374
1990's6 (27.27)18.2507
2000's3 (13.64)29.6817
2010's5 (22.73)24.3611
2020's1 (4.55)2.80

Authors

AuthorsStudies
Jacobs, JM; Jacobs, NJ3
Dailey, HA; Ferreira, GC1
Borotz, SE; Guerinot, ML; Jacobs, NJ1
De Maggio, AE; Jacobs, JM; Jacobs, NJ1
Bloomer, JR; Brenner, DA1
Furukawa, T; Kohno, H; Taketani, S; Tokunaga, R1
Gorman, N; Jacobs, JM; Jacobs, NJ; Sinclair, JF; Sinclair, PR; Walton, HS1
Hansson, M; Hederstedt, L1
Dailey, HA; Proulx, KL; Woodard, SI1
Yoshinaga, T1
Homuth, G; Jahn, D; Rompf, A; Schumann, W1
Ferrara, JD; Hill, CP; Kushner, JP; Labbe, P; Pflugrath, JW; Phillips, JD; Robinson, H; Warby, CA; Whitby, FG; Yang, C1
Dailey, HA; Dailey, TA; Woodruff, JH1
Heinemann, IU; Jahn, D; Jahn, M; Koch, M; Masoumi, A; Rohde, M1
Kobayashi, K; Masuda, T; Sato, N; Tajima, N; Wada, H1
Chen, J; Du, G; Kang, Z; Zhang, J1
Paw, BH; Ringel, AR; Yien, YY1
Dailey, HA; Dailey, TA; Gerdes, S; Jahn, D; Jahn, M; O'Brian, MR; Warren, MJ1
Gleadle, JM; MacGregor, MN; McNicholas, K1
Barinka, C; Havlinova, B; Kasparek, P; Korandova, Z; Kutil, Z; Milosevic, M; Novakova, Z; Ondrakova, M; Rohlena, J; Sandoval-Acuña, C; Truksa, J; Vrbacky, M1

Reviews

2 review(s) available for protoporphyrinogen and heme

ArticleYear
Prokaryotic Heme Biosynthesis: Multiple Pathways to a Common Essential Product.
    Microbiology and molecular biology reviews : MMBR, 2017, Volume: 81, Issue:1

    Topics: Aminolevulinic Acid; Archaea; Bacteria; Coproporphyrinogen Oxidase; Coproporphyrins; Heme; Iron; Protoporphyrins; Tetrapyrroles; Uroporphyrinogen Decarboxylase

2017
In order for the light to shine so brightly, the darkness must be present-why do cancers fluoresce with 5-aminolaevulinic acid?
    British journal of cancer, 2019, Volume: 121, Issue:8

    Topics: Amino Acid Transport Systems; Aminolevulinic Acid; Brain Neoplasms; Coproporphyrinogens; Ferrochelatase; Fluorescence; Glucose; Heme; Humans; Iron; MicroRNAs; Mitochondria; Mutation; NADP; Neoplasms; Oncogenes; Optical Imaging; Peptide Transporter 1; Photochemotherapy; Protoporphyrins; Skin Neoplasms; Symporters; Tumor Hypoxia; Tumor Microenvironment; Urinary Bladder Neoplasms

2019

Other Studies

20 other study(ies) available for protoporphyrinogen and heme

ArticleYear
The late steps of anaerobic heme biosynthesis in E. coli: role for quinones in protoporphyrinogen oxidation.
    Biochemical and biophysical research communications, 1977, Sep-09, Volume: 78, Issue:1

    Topics: Anaerobiosis; Escherichia coli; Fumarates; Heme; Kinetics; Porphyrinogens; Porphyrins; Protoporphyrins; Ultraviolet Rays; Vitamin K

1977
Mouse protoporphyrinogen oxidase. Kinetic parameters and demonstration of inhibition by bilirubin.
    The Biochemical journal, 1988, Mar-01, Volume: 250, Issue:2

    Topics: Animals; Bilirubin; Dicumarol; Flavoproteins; Heme; Kinetics; Mice; Mitochondrial Proteins; Oxidation-Reduction; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Oxygen; Protoporphyrinogen Oxidase; Protoporphyrins; Ubiquinone; Vitamin K

1988
Protoporphyrinogen oxidation, a step in heme synthesis in soybean root nodules and free-living rhizobia.
    Journal of bacteriology, 1989, Volume: 171, Issue:1

    Topics: Cell Membrane; Glycine max; Heme; Kinetics; Oxidation-Reduction; Plants; Porphyrins; Protoporphyrins; Rhizobium; Symbiosis

1989
Effect of unsaturated fatty acids on protoporphyrinogen oxidation, a step in heme and chlorophyll synthesis in plant organelles.
    Biochemical and biophysical research communications, 1984, Sep-28, Volume: 123, Issue:3

    Topics: Chlorophyll; Fatty Acids, Unsaturated; Heme; Hordeum; Linoleic Acid; Linoleic Acids; Mitochondria; Oleic Acid; Oleic Acids; Organoids; Oxidation-Reduction; Palmitic Acid; Palmitic Acids; Plants; Porphyrins; Protoporphyrins

1984
Protoporphyrinogen oxidation, an enzymatic step in heme and chlorophyll synthesis: partial characterization of the reaction in plant organelles and comparison with mammalian and bacterial systems.
    Archives of biochemistry and biophysics, 1984, Feb-15, Volume: 229, Issue:1

    Topics: Animals; Chlorophyll; Chloroplasts; Detergents; Heme; Hordeum; Mitochondria; Mitochondria, Liver; Organoids; Oxidation-Reduction; Oxidoreductases; Plants; Porphyrins; Protoporphyrins; Rats; Substrate Specificity

1984
Protoporphyrinogen oxidation in chloroplasts and plant mitochondria, a step in heme and chlorophyll synthesis.
    Archives of biochemistry and biophysics, 1982, Oct-01, Volume: 218, Issue:1

    Topics: Chlorophyll; Chloroplasts; Heme; Hordeum; Mitochondria; Oxidation-Reduction; Porphyrins; Protoporphyrins

1982
The enzymatic defect in variegate prophyria. Studies with human cultured skin fibroblasts.
    The New England journal of medicine, 1980, Apr-03, Volume: 302, Issue:14

    Topics: Adult; Biopsy; Coproporphyrins; Feces; Female; Ferrochelatase; Fibroblasts; Heme; Humans; Oxidation-Reduction; Oxidoreductases; Porphobilinogen; Porphyrias; Porphyrinogens; Protoporphyrins; Skin; Uroporphyrins

1980
Involvement of peripheral-type benzodiazepine receptors in the intracellular transport of heme and porphyrins.
    Journal of biochemistry, 1995, Volume: 117, Issue:4

    Topics: Animals; Binding Sites; Biological Transport; Carrier Proteins; Cells, Cultured; Chlorocebus aethiops; Heme; Hemin; Intracellular Fluid; Iron; Iron Radioisotopes; Kidney; Mice; Mitochondria, Liver; Porphyrins; Protoporphyrins; Receptors, GABA-A; Transfection

1995
Protoporphyrinogen accumulation in cultured hepatocytes treated with the diphenyl ether herbicide, acifluorfen.
    Cellular and molecular biology (Noisy-le-Grand, France), 1994, Volume: 40, Issue:7

    Topics: Aminolevulinic Acid; Animals; Cells, Cultured; Chick Embryo; Heme; Herbicides; Liver; Nitrobenzoates; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Phenyl Ethers; Protoporphyrinogen Oxidase; Protoporphyrins; Rats

1994
Bacillus subtilis HemY is a peripheral membrane protein essential for protoheme IX synthesis which can oxidize coproporphyrinogen III and protoporphyrinogen IX.
    Journal of bacteriology, 1994, Volume: 176, Issue:19

    Topics: Amino Acid Sequence; Bacillus subtilis; Base Sequence; Cloning, Molecular; Coproporphyrinogens; Heme; Kinetics; Membrane Proteins; Molecular Sequence Data; Mutation; Oxidation-Reduction; Porphyrinogens; Protoporphyrins; Recombinant Fusion Proteins; Sequence Analysis, DNA; Sequence Deletion; Species Specificity

1994
In situ conversion of coproporphyrinogen to heme by murine mitochondria: terminal steps of the heme biosynthetic pathway.
    Protein science : a publication of the Protein Society, 1993, Volume: 2, Issue:7

    Topics: Animals; Coproporphyrinogen Oxidase; Coproporphyrinogens; Ferrochelatase; Flavoproteins; Heme; Male; Mice; Mice, Inbred DBA; Mice, Inbred ICR; Mitochondria, Liver; Mitochondrial Proteins; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Protoporphyrinogen Oxidase; Protoporphyrins; Zinc

1993
Purification and properties of coproporphyrinogen III oxidase from bovine liver.
    Methods in enzymology, 1997, Volume: 281

    Topics: Animals; Cattle; Chromatography; Coproporphyrinogen Oxidase; Coproporphyrinogens; Enzyme Activation; Escherichia coli; Heme; Kinetics; Mice; Mitochondria, Liver; Molecular Weight; Protoporphyrins; Recombinant Proteins

1997
Transcriptional control of Bacillus subtilis hemN and hemZ.
    Journal of bacteriology, 1999, Volume: 181, Issue:19

    Topics: Amino Acid Sequence; Anaerobiosis; Bacillus subtilis; Bacterial Proteins; Base Sequence; Coproporphyrinogen Oxidase; Coproporphyrinogens; Enzyme Induction; Gene Expression Regulation, Bacterial; Genes, Bacterial; Genetic Complementation Test; Heme; Hydrogen Peroxide; Molecular Sequence Data; Mutation; Nitrates; Oxidation-Reduction; Oxidative Stress; Oxygen; Protoporphyrins; Salmonella typhimurium; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Transcription, Genetic

1999
Crystal structure of the oxygen-dependant coproporphyrinogen oxidase (Hem13p) of Saccharomyces cerevisiae.
    The Journal of biological chemistry, 2004, Sep-10, Volume: 279, Issue:37

    Topics: Amino Acid Sequence; Binding Sites; Catalysis; Coproporphyrinogen Oxidase; Coproporphyrinogens; Crystallography, X-Ray; Dimerization; DNA, Complementary; Heme; Humans; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutation; Protein Binding; Protein Conformation; Protoporphyrins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Homology, Amino Acid

2004
Examination of mitochondrial protein targeting of haem synthetic enzymes: in vivo identification of three functional haem-responsive motifs in 5-aminolaevulinate synthase.
    The Biochemical journal, 2005, Mar-01, Volume: 386, Issue:Pt 2

    Topics: 5-Aminolevulinate Synthetase; Amino Acid Motifs; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cloning, Molecular; Coproporphyrinogen Oxidase; Exons; Ferrochelatase; Flavoproteins; Heme; Humans; Liver Neoplasms, Experimental; Mice; Mitochondria; Mitochondrial Proteins; Molecular Sequence Data; Oxidoreductases Acting on CH-CH Group Donors; Peptide Fragments; Protoporphyrinogen Oxidase; Protoporphyrins

2005
Complex formation between protoporphyrinogen IX oxidase and ferrochelatase during haem biosynthesis in Thermosynechococcus elongatus.
    Microbiology (Reading, England), 2008, Volume: 154, Issue:Pt 12

    Topics: Coproporphyrinogen Oxidase; Cyanobacteria; Ferrochelatase; Heme; Immunohistochemistry; Immunoprecipitation; Microscopy, Electron; Models, Molecular; Multienzyme Complexes; Protoporphyrinogen Oxidase; Protoporphyrins

2008
Molecular phylogeny and intricate evolutionary history of the three isofunctional enzymes involved in the oxidation of protoporphyrinogen IX.
    Genome biology and evolution, 2014, Volume: 6, Issue:8

    Topics: Animals; Bacteria; Biosynthetic Pathways; Heme; Isoenzymes; Models, Molecular; Oxidation-Reduction; Phylogeny; Plants; Protoporphyrinogen Oxidase; Protoporphyrins; Tetrapyrroles

2014
Optimization of the heme biosynthesis pathway for the production of 5-aminolevulinic acid in Escherichia coli.
    Scientific reports, 2015, Feb-26, Volume: 5

    Topics: Aminolevulinic Acid; Biosynthetic Pathways; Cloning, Molecular; Enzyme Repression; Escherichia coli; Escherichia coli Proteins; Ferrochelatase; Gene Expression Regulation, Bacterial; Heme; Porphobilinogen Synthase; Protoporphyrinogen Oxidase; Protoporphyrins; Up-Regulation

2015
Mitochondrial transport of protoporphyrinogen IX in erythroid cells.
    Oncotarget, 2015, Aug-28, Volume: 6, Issue:25

    Topics: Animals; Biological Transport; Erythroid Cells; Heme; Homeostasis; Humans; Mice; Mitochondria; Protoporphyrins; Sequence Analysis, RNA; Zebrafish

2015
Generation and characterization of human U-2 OS cell lines with the CRISPR/Cas9-edited protoporphyrinogen oxidase IX gene.
    Scientific reports, 2022, 10-12, Volume: 12, Issue:1

    Topics: Aminolevulinic Acid; Cell Line; CRISPR-Cas Systems; Heme; Humans; Oxidoreductases; Porphyria, Variegate; Protoporphyrinogen Oxidase; Protoporphyrins

2022