Page last updated: 2024-09-03

protoporphyrinogen and aminolevulinic acid

protoporphyrinogen has been researched along with aminolevulinic acid in 9 studies

*Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS. [MeSH]

*Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS. [MeSH]

Compound Research Comparison

Studies
(protoporphyrinogen)
Trials
(protoporphyrinogen)
Recent Studies (post-2010)
(protoporphyrinogen)
Studies
(aminolevulinic acid)
Trials
(aminolevulinic acid)
Recent Studies (post-2010) (aminolevulinic acid)
531146,4756652,740

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (22.22)18.2507
2000's2 (22.22)29.6817
2010's3 (33.33)24.3611
2020's2 (22.22)2.80

Authors

AuthorsStudies
Gorman, N; Jacobs, JM; Jacobs, NJ; Sinclair, JF; Sinclair, PR; Walton, HS1
Bown, SG; Buonaccorsi, GA; Gorchein, A; Hatfield, AR; MacRobert, AJ; Regula, J; Spencer, GM; Thorpe, SM1
Beck, CF; Chekounova, E; Grimm, B; Papenbrock, J; Voronetskaya, V1
Butowska, W; Warchoł, W; Wołuń-Cholewa, M1
Chen, J; Du, G; Kang, Z; Zhang, J1
Dailey, HA; Dailey, TA; Gerdes, S; Jahn, D; Jahn, M; O'Brian, MR; Warren, MJ1
Gleadle, JM; MacGregor, MN; McNicholas, K1
Abe, M; Adachi, K; Hasegawa, M; Hirose, Y; Kuwahara, K; Mukherjee, J; Murayama, K; Nakae, S; Nishiyama, Y; Ohba, S; Pareira, ES; Pieper, RO; Sasaki, H; Yamada, S; Yamamoto, N1
Barinka, C; Havlinova, B; Kasparek, P; Korandova, Z; Kutil, Z; Milosevic, M; Novakova, Z; Ondrakova, M; Rohlena, J; Sandoval-Acuña, C; Truksa, J; Vrbacky, M1

Reviews

2 review(s) available for protoporphyrinogen and aminolevulinic acid

ArticleYear
Prokaryotic Heme Biosynthesis: Multiple Pathways to a Common Essential Product.
    Microbiology and molecular biology reviews : MMBR, 2017, Volume: 81, Issue:1

    Topics: Aminolevulinic Acid; Archaea; Bacteria; Coproporphyrinogen Oxidase; Coproporphyrins; Heme; Iron; Protoporphyrins; Tetrapyrroles; Uroporphyrinogen Decarboxylase

2017
In order for the light to shine so brightly, the darkness must be present-why do cancers fluoresce with 5-aminolaevulinic acid?
    British journal of cancer, 2019, Volume: 121, Issue:8

    Topics: Amino Acid Transport Systems; Aminolevulinic Acid; Brain Neoplasms; Coproporphyrinogens; Ferrochelatase; Fluorescence; Glucose; Heme; Humans; Iron; MicroRNAs; Mitochondria; Mutation; NADP; Neoplasms; Oncogenes; Optical Imaging; Peptide Transporter 1; Photochemotherapy; Protoporphyrins; Skin Neoplasms; Symporters; Tumor Hypoxia; Tumor Microenvironment; Urinary Bladder Neoplasms

2019

Trials

1 trial(s) available for protoporphyrinogen and aminolevulinic acid

ArticleYear
Photosensitisation and photodynamic therapy of oesophageal, duodenal, and colorectal tumours using 5 aminolaevulinic acid induced protoporphyrin IX--a pilot study.
    Gut, 1995, Volume: 36, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Colorectal Neoplasms; Duodenal Neoplasms; Esophageal Neoplasms; Female; Humans; Male; Microscopy, Fluorescence; Middle Aged; Photochemotherapy; Pilot Projects; Prodrugs; Protoporphyrins

1995

Other Studies

6 other study(ies) available for protoporphyrinogen and aminolevulinic acid

ArticleYear
Protoporphyrinogen accumulation in cultured hepatocytes treated with the diphenyl ether herbicide, acifluorfen.
    Cellular and molecular biology (Noisy-le-Grand, France), 1994, Volume: 40, Issue:7

    Topics: Aminolevulinic Acid; Animals; Cells, Cultured; Chick Embryo; Heme; Herbicides; Liver; Nitrobenzoates; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Phenyl Ethers; Protoporphyrinogen Oxidase; Protoporphyrins; Rats

1994
Characterization of Chlamydomonas mutants defective in the H subunit of Mg-chelatase.
    Molecular genetics and genomics : MGG, 2001, Volume: 266, Issue:3

    Topics: Amino Acid Sequence; Aminolevulinic Acid; Animals; Bacterial Proteins; Blotting, Southern; Blotting, Western; Carboxypeptidases; Chlamydomonas; Chlorophyll; Chloroplasts; Chromosomal Proteins, Non-Histone; Cloning, Molecular; DNA Primers; Frameshift Mutation; Fungal Proteins; Genetic Complementation Test; Lyases; Methyltransferases; Molecular Sequence Data; Polymerase Chain Reaction; Porphyrins; Protoporphyrins; RNA, Messenger; Saccharomyces cerevisiae Proteins

2001
Accumulation of protoporphyrin-IX in rat Leydig cells following induction by 5-aminolevulinic acid and tramadol.
    Photomedicine and laser surgery, 2007, Volume: 25, Issue:6

    Topics: Aminolevulinic Acid; Analgesics, Opioid; Animals; Leydig Cell Tumor; Male; Microscopy, Confocal; Photochemotherapy; Photosensitizing Agents; Protoporphyrins; Rats; Tramadol; Tumor Cells, Cultured

2007
Optimization of the heme biosynthesis pathway for the production of 5-aminolevulinic acid in Escherichia coli.
    Scientific reports, 2015, Feb-26, Volume: 5

    Topics: Aminolevulinic Acid; Biosynthetic Pathways; Cloning, Molecular; Enzyme Repression; Escherichia coli; Escherichia coli Proteins; Ferrochelatase; Gene Expression Regulation, Bacterial; Heme; Porphobilinogen Synthase; Protoporphyrinogen Oxidase; Protoporphyrins; Up-Regulation

2015
The Correlation of Fluorescence of Protoporphyrinogen IX and Status of Isocitrate Dehydrogenase in Gliomas.
    Neurosurgery, 2020, 08-01, Volume: 87, Issue:2

    Topics: Adult; Aged; Aminolevulinic Acid; Brain Neoplasms; Female; Glioma; Humans; Intraoperative Period; Isocitrate Dehydrogenase; Male; Middle Aged; Optical Imaging; Protoporphyrins; Retrospective Studies

2020
Generation and characterization of human U-2 OS cell lines with the CRISPR/Cas9-edited protoporphyrinogen oxidase IX gene.
    Scientific reports, 2022, 10-12, Volume: 12, Issue:1

    Topics: Aminolevulinic Acid; Cell Line; CRISPR-Cas Systems; Heme; Humans; Oxidoreductases; Porphyria, Variegate; Protoporphyrinogen Oxidase; Protoporphyrins

2022