Page last updated: 2024-08-16

protoporphyrin ix and pk 11195

protoporphyrin ix has been researched along with pk 11195 in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (41.18)18.2507
2000's3 (17.65)29.6817
2010's5 (29.41)24.3611
2020's2 (11.76)2.80

Authors

AuthorsStudies
Cagnotto, A; Cantoni, L; Codegoni, A; Ferrarese, C; Frigo, L; Mennini, T; Pecora, N; Rizzardini, M; Skorupska, M1
Antonenko, YN; Kinnally, KW; McEnery, MW; Snyder, SH; Tedeschi, H; Zorov, DB1
Matthews, EK; Ratcliffe, SL1
Farber, JL; Gilfor, E; Hoek, JB; Pastorino, JG; Simbula, G1
Alho, H; Berkovich, A; Bianchi, G; Cavaletti, G; Costa, E; Ferrarese, C; Guidotti, A; Marzorati, C1
Cantoni, L; Carelli, M; Tacconi, MT; Tsankova, V; Visentin, M1
Bender, AS; Norenberg, MD1
Cotter, FE; Fennell, DA1
Jayakumar, AR; Norenberg, MD; Panickar, KS1
Lacapère, JJ; Lindemann, P; Papadopoulos, V; Wendler, G1
Fujita, M; Hong, J; Innis, RB; Ozaki, H; Pike, VW; Verma, A; Zoghbi, SS1
Ferguson-Miller, S; Li, F; Meiler, J; Xia, Y1
Bruni, R; Ginter, C; Guo, Y; Hendrickson, WA; Kalathur, RC; Kloppmann, E; Kloss, B; Liu, Q; Rost, B1
Ferguson-Miller, S; Garavito, RM; Li, F; Liu, J; Zheng, Y1
Kazumura, K; Maruyama, W; Naoi, M; Osawa, T; Wu, Y1
Gouya, L; Hattab, C; Lacapere, JJ; Lefevre, SD; Manceau, H; Mirmiran, A; Ostuni, MA; Peoc'h, K; Puy, H; Schmitt, C; Sugier, HR1
Baburina, Y; Krestinina, O; Odinokova, I1

Reviews

1 review(s) available for protoporphyrin ix and pk 11195

ArticleYear
Controlling the mitochondrial gatekeeper for effective chemotherapy.
    British journal of haematology, 2000, Volume: 111, Issue:1

    Topics: Apoptosis; Arsenic Trioxide; Arsenicals; GABA-A Receptor Antagonists; Gene Expression Regulation; Genes, bcl-2; Humans; Intracellular Membranes; Isoquinolines; Mitochondria; Neoplasms; Oligonucleotides, Antisense; Oxides; Protoporphyrins

2000

Other Studies

16 other study(ies) available for protoporphyrin ix and pk 11195

ArticleYear
Hepatic protoporphyria is associated with a decrease in ligand binding for the mitochondrial benzodiazepine receptors in the liver.
    Biochemical pharmacology, 1992, Sep-25, Volume: 44, Issue:6

    Topics: 5-Aminolevulinate Synthetase; Adenosine Triphosphate; Animals; Binding Sites; Cerebral Cortex; Dicarbethoxydihydrocollidine; Ferrochelatase; Isoquinolines; Liver; Male; Mitochondria, Liver; Porphyrias; Porphyrins; Protoporphyrins; Rats; Receptors, GABA-A

1992
Mitochondrial benzodiazepine receptor linked to inner membrane ion channels by nanomolar actions of ligands.
    Proceedings of the National Academy of Sciences of the United States of America, 1993, Feb-15, Volume: 90, Issue:4

    Topics: Animals; Benzodiazepinones; Clonazepam; Convulsants; Flumazenil; Intracellular Membranes; Ion Channels; Isoquinolines; Male; Membrane Potentials; Mitochondria, Heart; Protoporphyrins; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Submitochondrial Particles

1993
Modification of the photodynamic action of delta-aminolaevulinic acid (ALA) on rat pancreatoma cells by mitochondrial benzodiazepine receptor ligands.
    British journal of cancer, 1995, Volume: 71, Issue:2

    Topics: Aminolevulinic Acid; Animals; Benzodiazepines; Benzodiazepinones; Cell Division; Cell Survival; Clonazepam; Flumazenil; Isoquinolines; Ligands; Mitochondria; Oxygen; Pancreatic Neoplasms; Photochemotherapy; Protoporphyrins; Radiation-Protective Agents; Radiation-Sensitizing Agents; Rats; Receptors, GABA-A; Singlet Oxygen; Tumor Cells, Cultured

1995
Protoporphyrin IX, an endogenous ligand of the peripheral benzodiazepine receptor, potentiates induction of the mitochondrial permeability transition and the killing of cultured hepatocytes by rotenone.
    The Journal of biological chemistry, 1994, Dec-09, Volume: 269, Issue:49

    Topics: Adenosine Triphosphate; Animals; Cell Survival; Cells, Cultured; Diazepam; Drug Synergism; Intracellular Membranes; Isoquinolines; Ligands; Liver; Male; Membrane Potentials; Mitochondria, Liver; Permeability; Protoporphyrins; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Rotenone

1994
Topology of two DBI receptors in human lymphocytes.
    Life sciences, 1993, Volume: 52, Issue:15

    Topics: Amino Acid Sequence; Animals; Benzodiazepinones; Binding Sites; Binding, Competitive; Carrier Proteins; Cell Membrane; Diazepam Binding Inhibitor; Humans; Immunohistochemistry; In Vitro Techniques; Isoquinolines; Lymphocytes; Mitochondria; Molecular Sequence Data; Peptide Fragments; Protoporphyrins; Rats; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear

1993
Peripheral benzodiazepine receptor ligands in rat liver mitochondria: effect on 27-hydroxylation of cholesterol.
    European journal of pharmacology, 1996, Mar-28, Volume: 299, Issue:1-3

    Topics: Animals; Dicarbethoxydihydrocollidine; Dose-Response Relationship, Drug; Hydroxycholesterols; Isoquinolines; Male; Mitochondria, Liver; Protoporphyrins; Rats; Rats, Sprague-Dawley; Receptors, GABA-A

1996
Effect of benzodiazepines and neurosteroids on ammonia-induced swelling in cultured astrocytes.
    Journal of neuroscience research, 1998, Dec-01, Volume: 54, Issue:5

    Topics: Ammonia; Astrocytes; Atrial Natriuretic Factor; Benzodiazepines; Benzodiazepinones; Brain Edema; Cell Size; Clonazepam; Dehydroepiandrosterone Sulfate; Desoxycorticosterone; Diazepam; Diazepam Binding Inhibitor; Flumazenil; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Isoquinolines; Nerve Tissue Proteins; Neuropeptides; Peptide Fragments; Pregnanolone; Pregnenolone; Protoporphyrins; Receptors, GABA-A; Steroids; Up-Regulation

1998
Effects on free radical generation by ligands of the peripheral benzodiazepine receptor in cultured neural cells.
    Journal of neurochemistry, 2002, Volume: 83, Issue:5

    Topics: Animals; Antioxidants; Astrocytes; Benzodiazepinones; Binding, Competitive; Cells, Cultured; Clonazepam; Cyclosporine; Dose-Response Relationship, Drug; Free Radicals; Isoquinolines; Ligands; Microglia; Mitochondria; Neurons; Protoporphyrins; Rats; Receptors, GABA-A

2002
Protoporphyrin IX binding and transport by recombinant mouse PBR.
    Biochemical and biophysical research communications, 2003, Nov-28, Volume: 311, Issue:4

    Topics: Animals; Binding, Competitive; Carrier Proteins; Cholesterol; Escherichia coli Proteins; Integration Host Factors; Isoquinolines; Mice; Protein Binding; Protein Transport; Protoporphyrins; Receptors, GABA; Recombinant Proteins

2003
In vivo binding of protoporphyrin IX to rat translocator protein imaged with positron emission tomography.
    Synapse (New York, N.Y.), 2010, Volume: 64, Issue:8

    Topics: Acetamides; Animals; Binding, Competitive; Carbon Radioisotopes; Carrier Proteins; Isoquinolines; Male; Mitochondria; Organ Specificity; Porphyrias; Positron-Emission Tomography; Protoporphyrins; Pyridines; Rats; Receptors, GABA-A

2010
Characterization and modeling of the oligomeric state and ligand binding behavior of purified translocator protein 18 kDa from Rhodobacter sphaeroides.
    Biochemistry, 2013, Aug-27, Volume: 52, Issue:34

    Topics: Amino Acid Sequence; Apoptosis; Binding, Competitive; Carrier Proteins; Cholesterol; Cryoelectron Microscopy; Crystallization; Isoquinolines; Membrane Proteins; Mitochondrial Membranes; Protein Multimerization; Protoporphyrins; Receptors, GABA-A; Rhodobacter sphaeroides; Sequence Alignment

2013
Protein structure. Structure and activity of tryptophan-rich TSPO proteins.
    Science (New York, N.Y.), 2015, Jan-30, Volume: 347, Issue:6221

    Topics: Amino Acid Sequence; Bacillus cereus; Bacterial Proteins; Binding Sites; Crystallography, X-Ray; Isoquinolines; Ligands; Membrane Transport Proteins; Molecular Sequence Data; Mutant Proteins; Protein Conformation; Protein Multimerization; Protein Structure, Secondary; Protein Subunits; Protoporphyrins; Reactive Oxygen Species; Tryptophan

2015
Protein structure. Crystal structures of translocator protein (TSPO) and mutant mimic of a human polymorphism.
    Science (New York, N.Y.), 2015, Jan-30, Volume: 347, Issue:6221

    Topics: Amino Acid Sequence; Bacterial Proteins; Binding Sites; Cholesterol; Crystallography, X-Ray; Humans; Hydrogen Bonding; Isoquinolines; Ligands; Membrane Transport Proteins; Models, Molecular; Molecular Sequence Data; Mutant Proteins; Polymorphism, Single Nucleotide; Porphyrins; Protein Conformation; Protein Multimerization; Protein Structure, Secondary; Protoporphyrins; Receptors, GABA; Rhodobacter sphaeroides

2015
Rasagiline and selegiline suppress calcium efflux from mitochondria by PK11195-induced opening of mitochondrial permeability transition pore: a novel anti-apoptotic function for neuroprotection.
    Journal of neural transmission (Vienna, Austria : 1996), 2015, Volume: 122, Issue:10

    Topics: Apoptosis; Calcium; Cell Line, Tumor; Cyclosporine; Cytoplasm; Humans; Indans; Indoleacetic Acids; Isoquinolines; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Monoamine Oxidase Inhibitors; Neuroprotective Agents; Proto-Oncogene Proteins c-bcl-2; Protoporphyrins; Receptors, GABA; Selegiline; Superoxides

2015
TSPO2 translocates 5-aminolevulinic acid into human erythroleukemia cells.
    Biology of the cell, 2020, Volume: 112, Issue:4

    Topics: Aminolevulinic Acid; Biological Transport; Cell Membrane; Green Fluorescent Proteins; Humans; Isoquinolines; K562 Cells; Leukemia, Erythroblastic, Acute; Levulinic Acids; Protoporphyrins; Receptors, Cytoplasmic and Nuclear; Transfection

2020
The Effects of PK11195 and Protoporphyrin IX Can Modulate Chronic Alcohol Intoxication in Rat Liver Mitochondria under the Opening of the Mitochondrial Permeability Transition Pore.
    Cells, 2020, 07-24, Volume: 9, Issue:8

    Topics: Alcoholism; Animals; Antineoplastic Agents; Humans; Isoquinolines; Mitochondria, Liver; Mitochondrial Permeability Transition Pore; Photosensitizing Agents; Protoporphyrins; Rats; Signal Transduction

2020