protoporphyrin ix has been researched along with deferoxamine in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.33) | 18.7374 |
| 1990's | 7 (23.33) | 18.2507 |
| 2000's | 8 (26.67) | 29.6817 |
| 2010's | 11 (36.67) | 24.3611 |
| 2020's | 3 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Affabris, E; Battistini, A; Coccia, EM; Fiorucci, G; Hentze, MW; Profita, V; Romeo, G; Testa, U | 1 |
| Kitchin, KT | 1 |
| Farshi, SS; Hasan, T; Iinuma, S; Ortel, B | 1 |
| Girotti, AW; Lin, F | 1 |
| Krasner, N; Lombard, M; O'Toole, P; Tan, WC | 1 |
| Battistini, A; Coccia, EM; Del Russo, N; Marziali, G; Orsatti, R; Perrotti, E; Stellacci, E; Testa, U | 1 |
| Kvam, E; Pourzand, C; Reelfs, O; Tyrrell, RM | 1 |
| Abels, C; Botzlar, A; Goetz, AE; Langer, S; Pahernik, S; Rick, K; Szeimies, RM | 1 |
| Brooke, RC; Choudry, K; Farrar, W; Rhodes, LE | 1 |
| Beraud, JJ; Canaud, B; Cristol, JP; Descomps, B; Klouche, K; Morena, M | 1 |
| Abraham, NG; Ahmad, M; Chow, JL; Gupte, SA; Mingone, CJ; Wolin, MS | 1 |
| Alvarez, MG; Batlle, A; Fukuda, H; Lacelli, MS; Rivarola, V | 1 |
| Curnow, A; Pye, A | 1 |
| Fujita, H; Inoue, K; Inoue, M; Ogino, T; Okimura, Y; Sasaki, J; Shuin, T; Utsumi, K; Yano, H; Yasuda, T | 1 |
| Jiang, S; Liu, X; Xia, Y; Xiong, L; Yang, J | 1 |
| Fujita, H; Furihata, M; Inoue, K; Kamada, M; Karashima, T; Kurabayashi, A; Sasaki, J; Shuin, T; Utsumi, K | 1 |
| Huang, Y; Jiang, S; Lin, L; Liu, X; Xia, Y; Xiong, L | 1 |
| Harada, H; Hasegawa, S; Morita, KI; Nakajima, Y; Omura, K; Tsuda, H; Uekusa, M | 1 |
| Fujita, H; Fukuhara, H; Furihata, M; Inoue, K; Kurabayashi, A; Nagakawa, K; Shuin, T; Tsuda, M; Utsumi, K | 1 |
| Fujita, H; Inoue, K; Katase, N; Nagatsuka, H; Ohuchi, H; Sasaki, J; Utsumi, K; Yamamoto, M | 1 |
| Fujita, H; Fukuhara, H; Furihata, M; Inoue, K; Kurabayashi, A; Sasaki, J; Shuin, T; Utsumi, K | 1 |
| Ferreira, GC; Fratz, EJ; Hunter, GA | 1 |
| Elenbaas, JS; Hoenerhoff, MJ; Lentz, SI; Liu, Y; Maitra, D; Nelson, B; Omary, MB; Shavit, JA | 1 |
| Chapman, MS; Davis, SC; de Souza, AL; Gunn, J; Hasan, T; Kanick, SC; Marra, K; Maytin, EV; Pogue, BW; Samkoe, KS | 1 |
| Hagiya, Y; Kokubu, Y; Murota, Y; Ogura, SI; Sugiyama, Y; Tabu, K; Taga, T; Wang, W | 1 |
| Braun, A; Chen, B; Howley, R; Kraus, D; Mansi, M; Myers, KA; Palasuberniam, P | 1 |
| Basrur, V; Carter, EL; Herrmann, H; Lehnert, N; Maitra, D; Nesvizhskii, AI; Omary, MB; Osawa, Y; Ragsdale, SW; Richardson, R; Rittié, L; Wolf, MW; Zhang, H | 1 |
| Banerjee, R; Maitra, D; Omary, MB; Pinsky, BM; Soherawardy, A; Zheng, H | 1 |
| Chen, B; Howley, R; Mansi, M; Restrepo, J; Shinde, J | 1 |
| Chen, Y; Deng, H; Feng, M; Guo, L; Yang, L | 1 |
1 trial(s) available for protoporphyrin ix and deferoxamine
| Article | Year |
|---|---|
The effect of an iron chelating agent on protoporphyrin IX levels and phototoxicity in topical 5-aminolaevulinic acid photodynamic therapy.
Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Bowen's Disease; Carcinoma, Basal Cell; Deferoxamine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Erythema; Female; Fluorescence; Humans; Iontophoresis; Iron Chelating Agents; Male; Middle Aged; Photochemotherapy; Protoporphyrins; Skin Neoplasms | 2003 |
29 other study(ies) available for protoporphyrin ix and deferoxamine
| Article | Year |
|---|---|
Modulation of ferritin H-chain expression in Friend erythroleukemia cells: transcriptional and translational regulation by hemin.
Topics: Animals; Base Sequence; Deferoxamine; Ferric Compounds; Ferritins; Gene Expression Regulation, Neoplastic; Hemin; Leukemia, Erythroblastic, Acute; Mice; Molecular Sequence Data; Polyribosomes; Protein Biosynthesis; Protoporphyrins; Quaternary Ammonium Compounds; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured | 1992 |
Regulation of rat hepatic delta-aminolevulinic acid synthetase and heme oxygenase activities: evidence for control by heme and against mediation by prosthetic iron.
Topics: 5-Aminolevulinate Synthetase; Animals; Bilirubin; Cobalt; Deferoxamine; Dextrans; Edetic Acid; Heme; Heme Oxygenase (Decyclizing); Iron-Dextran Complex; Kinetics; Liver; Male; Mixed Function Oxygenases; Protoporphyrins; Rats | 1983 |
A mechanistic study of cellular photodestruction with 5-aminolaevulinic acid-induced porphyrin.
Topics: Aminolevulinic Acid; Animals; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cell Division; Cells, Cultured; Deferoxamine; Ferrochelatase; Fibroblasts; Humans; Melanoma; Mice; Microscopy, Fluorescence; Mitochondria; Photochemotherapy; Protoporphyrins; Rats; Skin Neoplasms; Spectrometry, Fluorescence; Tumor Cells, Cultured; Up-Regulation; Urinary Bladder Neoplasms; Verapamil | 1994 |
Hyperresistance of leukemia cells to photodynamic inactivation after long-term exposure to hemin.
Topics: Animals; Antidotes; Apoferritins; Cell Survival; Deferoxamine; Drug Resistance; Enzyme Induction; Ferric Compounds; Heme Oxygenase (Decyclizing); Hemin; Hydrogen Peroxide; Hydroxyquinolines; Leukemia L1210; Lipid Peroxidation; Photochemotherapy; Photosensitizing Agents; Protoporphyrins; Pyrimidinones; Thiobarbituric Acid Reactive Substances | 1996 |
Enhancement of photodynamic therapy in gastric cancer cells by removal of iron.
Topics: Aminolevulinic Acid; Cell Survival; Deferoxamine; Ferrochelatase; Humans; Iron; Photochemotherapy; Photosensitizing Agents; Protoporphyrins; Siderophores; Stomach Neoplasms; Tumor Cells, Cultured | 1997 |
Regulation of expression of ferritin H-chain and transferrin receptor by protoporphyrin IX.
Topics: Animals; Cell Count; Chloramphenicol O-Acetyltransferase; Deferoxamine; Ferritins; Gene Expression Regulation; Genes, Reporter; Iron; Iron-Regulatory Proteins; Iron-Sulfur Proteins; Leukemia, Experimental; Mice; Protein Binding; Protein Biosynthesis; Protoporphyrins; Receptors, Transferrin; RNA-Binding Proteins; RNA, Messenger; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1997 |
The iron regulatory protein can determine the effectiveness of 5-aminolevulinic acid in inducing protoporphyrin IX in human primary skin fibroblasts.
Topics: Aminolevulinic Acid; Cells, Cultured; Deferoxamine; Humans; Iron-Regulatory Proteins; Iron-Sulfur Proteins; Photochemotherapy; Protoporphyrins; RNA; RNA-Binding Proteins; Skin; Ultraviolet Rays | 1999 |
Active and higher intracellular uptake of 5-aminolevulinic acid in tumors may be inhibited by glycine.
Topics: Aminolevulinic Acid; Animals; Biological Transport; Cricetinae; Deferoxamine; Diffusion Chambers, Culture; Glycine; Male; Melanoma, Amelanotic; Mesocricetus; Neoplasm Transplantation; Phenanthrolines; Protoporphyrins; Skin Neoplasms; Spectrometry, Fluorescence | 1999 |
Mechanism of in vitro heme-induced LDL oxidation: effects of antioxidants.
Topics: Antioxidants; Deferoxamine; Dose-Response Relationship, Drug; Heme; Humans; Hydrogen Peroxide; Iron Chelating Agents; Lipid Peroxidation; Lipoproteins, LDL; Oxidation-Reduction; Protoporphyrins; Vitamins | 2004 |
Protoporphyrin IX generation from delta-aminolevulinic acid elicits pulmonary artery relaxation and soluble guanylate cyclase activation.
Topics: Aminolevulinic Acid; Animals; Cattle; Deferoxamine; Dose-Response Relationship, Drug; Enzyme Activation; Gene Expression Regulation, Enzymologic; Guanylate Cyclase; Heme; Iron; Models, Biological; Organ Culture Techniques; Oxidation-Reduction; Photosensitizing Agents; Protoporphyrins; Pulmonary Artery; Receptors, Cytoplasmic and Nuclear; Serotonin; Soluble Guanylyl Cyclase; Vasodilation | 2006 |
5-aminolevulinic acid-mediated photodynamic therapy on Hep-2 and MCF-7c3 cells.
Topics: Adenocarcinoma; Aminolevulinic Acid; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Deferoxamine; Dose-Response Relationship, Drug; Drug Combinations; Drug Screening Assays, Antitumor; Drug Synergism; Humans; Light; Liver Neoplasms; Microscopy, Fluorescence; Photochemotherapy; Photosensitizing Agents; Protoporphyrins | 2007 |
Biochemical manipulation via iron chelation to enhance porphyrin production from porphyrin precursors.
Topics: Aminolevulinic Acid; Carcinoma, Squamous Cell; Cell Line, Tumor; Deferoxamine; Dose-Response Relationship, Drug; Drug Combinations; Drug Screening Assays, Antitumor; Drug Synergism; Esters; Fibroblasts; Fluorescence; Humans; Iron Chelating Agents; Lung; Microscopy, Fluorescence; Photochemotherapy; Photosensitizing Agents; Protoporphyrins; Pyridones | 2007 |
Regulation of 5-aminolevulinic acid-dependent protoporphyrin IX accumulations in human histiocytic lymphoma U937 cells.
Topics: Aminolevulinic Acid; Chlorides; Deferoxamine; Humans; Lymphoma, Large B-Cell, Diffuse; Manganese Compounds; Mesoporphyrins; Protoporphyrins; U937 Cells | 2007 |
Desferrioxamine shows different potentials for enhancing 5-aminolaevulinic acid-based photodynamic therapy in several cutaneous cell lines.
Topics: Aminolevulinic Acid; Cell Death; Cell Line; Deferoxamine; Drug Synergism; Fibroblasts; Humans; Iron Chelating Agents; Photochemotherapy; Photosensitizing Agents; Protoporphyrins; Skin Diseases | 2010 |
Regulation of 5-aminolevulinic acid-mediated protoporphyrin IX accumulation in human urothelial carcinomas.
Topics: Aminolevulinic Acid; beta-Alanine; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Carcinoma, Transitional Cell; Cell Line, Tumor; Deferoxamine; Ferrochelatase; Flow Cytometry; Humans; Microscopy, Fluorescence; Mitochondria; Nitroso Compounds; Oxidative Phosphorylation; Photosensitizing Agents; Protoporphyrins; Time Factors; Urinary Bladder Neoplasms; Urothelium | 2009 |
A comparative study on the enhancement efficacy of specific and non-specific iron chelators for protoporphyrin IX production and photosensitization in HaCat cells.
Topics: Aminolevulinic Acid; Cell Line, Transformed; Deferoxamine; Edetic Acid; Humans; Iron Chelating Agents; Keratinocytes; Photosensitivity Disorders; Photosensitizing Agents; Protoporphyrins | 2009 |
Uptake and kinetics of 5-aminolevulinic acid in oral squamous cell carcinoma.
Topics: Amino Acids, Neutral; Animals; Carcinoma, Squamous Cell; Cell Differentiation; Deferoxamine; Drug Combinations; Drug Synergism; Fluorescence; Humans; Male; Mice; Mice, SCID; Mouth Neoplasms; Photochemotherapy; Photosensitizing Agents; Protoporphyrins; Tumor Cells, Cultured | 2010 |
Photodynamic therapy involves an antiangiogenic mechanism and is enhanced by ferrochelatase inhibitor in urothelial carcinoma.
Topics: Aminolevulinic Acid; Angiogenesis Inhibitors; Animals; Apoptosis; Carcinoma, Transitional Cell; Cell Line; Deferoxamine; Enzyme Inhibitors; Ferrochelatase; Flow Cytometry; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Mice; Mice, Inbred BALB C; Photochemotherapy; Photosensitizing Agents; Protoporphyrins; Urinary Bladder Neoplasms; Xenograft Model Antitumor Assays | 2013 |
Improvement of the efficacy of 5-aminolevulinic acid-mediated photodynamic treatment in human oral squamous cell carcinoma HSC-4.
Topics: Amino Acid Chloromethyl Ketones; Aminolevulinic Acid; Apoptosis; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Blood Proteins; Carcinoma, Squamous Cell; Caspase Inhibitors; Cell Line, Tumor; Deferoxamine; Ferrochelatase; Gene Silencing; Humans; Lipid Peroxidation; Mouth Neoplasms; Neoplasm Proteins; Photochemotherapy; Photosensitizing Agents; Protoporphyrins; Siderophores | 2013 |
The inhibition of ferrochelatase enhances 5-aminolevulinic acid-based photodynamic action for prostate cancer.
Topics: Aminolevulinic Acid; Animals; Apoptosis; Cell Line, Tumor; Chloroquine; Deferoxamine; Drug Synergism; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Photochemotherapy; Photosensitizing Agents; Prostatic Neoplasms; Protoporphyrins | 2013 |
Expression of murine 5-aminolevulinate synthase variants causes protoporphyrin IX accumulation and light-induced mammalian cell death.
Topics: 5-Aminolevulinate Synthetase; Animals; Cell Death; Cell Membrane; Culture Media; Deferoxamine; Glycine; Green Fluorescent Proteins; HeLa Cells; Humans; K562 Cells; Light; Mice; Mutant Proteins; Paclitaxel; Plasmids; Protoporphyrins; Transfection | 2014 |
A precursor-inducible zebrafish model of acute protoporphyria with hepatic protein aggregation and multiorganelle stress.
Topics: Aminolevulinic Acid; Animals; Deferoxamine; Disease Models, Animal; Genetic Predisposition to Disease; Larva; Liver; Mice; Photosensitizing Agents; Protein Aggregation, Pathological; Protoporphyria, Erythropoietic; Protoporphyrins; Siderophores; Stress, Physiological; Zebrafish | 2016 |
Comparing desferrioxamine and light fractionation enhancement of ALA-PpIX photodynamic therapy in skin cancer.
Topics: Aminolevulinic Acid; Animals; Carcinoma, Squamous Cell; Cell Line, Tumor; Deferoxamine; Dose Fractionation, Radiation; Dose-Response Relationship, Radiation; Female; Heme; Humans; Lasers, Semiconductor; Lighting; Mice; Mice, Nude; Photochemotherapy; Photosensitizing Agents; Protoporphyrins; Random Allocation; Siderophores; Skin Neoplasms; Tumor Burden; Xenograft Model Antitumor Assays | 2016 |
Enhancement of 5-aminolevulinic acid-based fluorescence detection of side population-defined glioma stem cells by iron chelation.
Topics: Aminolevulinic Acid; Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; Biotransformation; Brain Neoplasms; Cell Line, Tumor; Cell Lineage; Computational Biology; Deferoxamine; Female; Fluorescent Dyes; Glioma; Heme Oxygenase-1; Humans; Iron Chelating Agents; Levulinic Acids; Mice; Mice, Inbred NOD; Neoplasm Transplantation; Neoplastic Stem Cells; Photosensitizing Agents; Protoporphyrins; Rats; Reserpine | 2017 |
Ferrochelatase Deficiency Abrogated the Enhancement of Aminolevulinic Acid-mediated Protoporphyrin IX by Iron Chelator Deferoxamine.
Topics: Aminolevulinic Acid; Breast Neoplasms; Cell Line, Tumor; Deferoxamine; Epithelial Cells; Female; Ferrochelatase; Gene Silencing; Humans; Photochemotherapy; Photosensitizing Agents; Protoporphyrins; Siderophores | 2019 |
Oxygen and Conformation Dependent Protein Oxidation and Aggregation by Porphyrins in Hepatocytes and Light-Exposed Cells.
Topics: Aminolevulinic Acid; Animals; Carcinoma, Hepatocellular; Cell Line; Deferoxamine; Heme; Hepatocytes; Humans; Liver; Liver Neoplasms; Male; Mice; Mice, Inbred C57BL; Oxygen; Photosensitivity Disorders; Photosensitizing Agents; Porphyrias; Porphyrins; Protein Aggregates; Protein Conformation; Protoporphyrins | 2019 |
Protein-aggregating ability of different protoporphyrin-IX nanostructures is dependent on their oxidation and protein-binding capacity.
Topics: Aminolevulinic Acid; Animals; Binding Sites; Cattle; Cell Line; Deferoxamine; Dimerization; Humans; Hydrogen-Ion Concentration; Models, Biological; Nanostructures; Oxidation-Reduction; Protein Aggregates; Protein Binding; Protein Structure, Secondary; Protoporphyrins; Serum Albumin, Bovine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 2021 |
Analysis of Renal Cell Carcinoma Cell Response to the Enhancement of 5-aminolevulinic Acid-mediated Protoporphyrin IX Fluorescence by Iron Chelator Deferoxamine
Topics: Aminolevulinic Acid; Carcinoma, Renal Cell; Cell Line, Tumor; Deferoxamine; Fluorescence; Heme; Humans; Iron; Iron Chelating Agents; Kidney Neoplasms; Photochemotherapy; Photosensitizing Agents; Protoporphyrins | 2023 |
Desferrioxamine Enhances 5-Aminolaevulinic Acid- Induced Protoporphyrin IX Accumulation and Therapeutic Efficacy for Hypertrophic Scar.
Topics: Aminolevulinic Acid; Cicatrix, Hypertrophic; Deferoxamine; Humans; Iron Chelating Agents; Photochemotherapy; Photosensitizing Agents; Protoporphyrins | 2023 |