Page last updated: 2024-09-05

protohypericin and hypericin

protohypericin has been researched along with hypericin in 10 studies

Compound Research Comparison

Studies
(protohypericin)
Trials
(protohypericin)
Recent Studies (post-2010)
(protohypericin)
Studies
(hypericin)
Trials
(hypericin)
Recent Studies (post-2010) (hypericin)
160598231380

Protein Interaction Comparison

ProteinTaxonomyprotohypericin (IC50)hypericin (IC50)
Cytochrome P450 3A4Homo sapiens (human)8.7
Corticotropin-releasing factor receptor 1Homo sapiens (human)0.3
Cystathionine beta-synthaseHomo sapiens (human)3.1
Alpha-synucleinHomo sapiens (human)7.5
Glutathione reductaseSaccharomyces cerevisiae S288C3.67
Integrase Human immunodeficiency virus 110
Cysteine protease ATG4BHomo sapiens (human)8.9

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (30.00)18.2507
2000's4 (40.00)29.6817
2010's3 (30.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cellárová, E; Kosuth, J; Kusari, S; Spiteller, M; Zühlke, S1
Lotz, R; Piperopoulos, G; Schmierer, T; Wixforth, A; Zeller, KP1
Augustijns, P; de Witte, PA; Kamuhabwa, AR1
de Witte, PA; Delaey, EM; Kamuhabwa, AR; Vandenbogaerde, AL1
Baraldi, M; De Witte, P; Kamuhabwa, A; Merlevede, W; Puia, G; Truzzi, C; Vandenbogaerde, A; Zanoli, P1
Di Gregorio, F; Girardin, P; Poutaraud, A; Tin, VC1
Hansen, SH; Jensen, AG1
Feng, Y; Gao, M; Huang, D; Jiang, C; Ni, Y; Shao, H; Sun, Z; Wang, X; Yang, S; Yin, Z; Zhang, D; Zhang, J1
Čellárová, E; Janfelt, C; Kimáková, K; Kucharíková, A1
Astrath, NGC; Caetano, W; Camargo, VG; Gonçalves, RS; Herculano, LS; Hioka, N; Lukasievicz, GVB; Malacarne, LC; Pereira, PCS; Zanuto, VS1

Other Studies

10 other study(ies) available for protohypericin and hypericin

ArticleYear
Light-independent metabolomics of endophytic Thielavia subthermophila provides insight into microbial hypericin biosynthesis.
    Journal of natural products, 2009, Volume: 72, Issue:10

    Topics: Anthracenes; Antineoplastic Agents; Base Sequence; Drug Screening Assays, Antitumor; Emodin; Humans; Hypericum; Light; Metabolomics; Molecular Structure; Perylene; Sordariales

2009
Determination of naphthodianthrones in plant extracts from Hypericum perforatum L. by liquid chromatography-electrospray mass spectrometry.
    Journal of chromatography. B, Biomedical sciences and applications, 1997, Aug-01, Volume: 695, Issue:2

    Topics: Anthracenes; Chromatography, High Pressure Liquid; Mass Spectrometry; Perylene; Plant Extracts; Plants, Medicinal

1997
In vitro transport and uptake of protohypericin and hypericin in the Caco-2 model.
    International journal of pharmaceutics, 1999, Oct-15, Volume: 188, Issue:1

    Topics: Anthracenes; Biological Transport; Caco-2 Cells; Dose-Response Relationship, Drug; Humans; Hypericum; Light; Perylene; Plant Extracts; Plants, Medicinal; Time Factors

1999
Photocytotoxicity of protohypericin after photoconversion to hypericin.
    Planta medica, 1999, Volume: 65, Issue:8

    Topics: Anthracenes; HeLa Cells; Humans; Perylene; Photosensitizing Agents

1999
Evidence that total extract of Hypericum perforatum affects exploratory behavior and exerts anxiolytic effects in rats.
    Pharmacology, biochemistry, and behavior, 2000, Volume: 65, Issue:4

    Topics: Animals; Anthracenes; Anti-Anxiety Agents; Cerebellum; Electrophysiology; Exploratory Behavior; Flumazenil; GABA Modulators; GABA-A Receptor Antagonists; Hypericum; Male; Motor Activity; Patch-Clamp Techniques; Perylene; Plant Extracts; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Receptors, GABA; Receptors, N-Methyl-D-Aspartate

2000
Effect of light on hypericins contents in fresh flowering top parts and in an extract of St. John's Wort (Hypericum perforatum).
    Planta medica, 2001, Volume: 67, Issue:3

    Topics: Anthracenes; Antidepressive Agents; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Hypericum; Perylene; Pigments, Biological; Plant Extracts; Plant Leaves; Plant Stems; Plants, Medicinal; Sunlight

2001
Separation of hypericins and hyperforins in extracts of Hypericum perforatum L. using non-aqueous capillary electrophoresis with reversed electro-osmotic flow.
    Journal of pharmaceutical and biomedical analysis, 2002, Jan-01, Volume: 27, Issue:1-2

    Topics: Anthracenes; Antidepressive Agents; Bridged Bicyclo Compounds; Electrolytes; Electrophoresis, Capillary; Hypericum; Molecular Structure; Osmotic Pressure; Perylene; Phloroglucinol; Plant Extracts; Reproducibility of Results; Rheology; Solvents; Terpenes

2002
Effects of skeleton structure on necrosis targeting and clearance properties of radioiodinated dianthrones.
    Journal of drug targeting, 2016, Volume: 24, Issue:6

    Topics: Animals; Anthracenes; Cell Line, Tumor; Disease Models, Animal; Drug Delivery Systems; Drug Design; Emodin; Humans; Hydrogen Peroxide; Iodine Radioisotopes; Lung Neoplasms; Male; Necrosis; Perylene; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Tissue Distribution

2016
Interspecific variation in localization of hypericins and phloroglucinols in the genus Hypericum as revealed by desorption electrospray ionization mass spectrometry imaging.
    Physiologia plantarum, 2016, Volume: 157, Issue:1

    Topics: Anthracenes; Hypericum; Perylene; Phloroglucinol; Plant Leaves; Species Specificity; Spectrometry, Mass, Electrospray Ionization; Terpenes

2016
From Protohypericin to Hypericin: Photoconversion Analysis Using a Time-Resolved Thermal Lens Technique.
    Applied spectroscopy, 2019, Volume: 73, Issue:8

    Topics: Anthracenes; Lenses; Perylene; Photochemotherapy; Photosensitizing Agents

2019