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protocatechualdehyde and 3,4-dihydroxyphenyllactic acid

protocatechualdehyde has been researched along with 3,4-dihydroxyphenyllactic acid in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.13)18.7374
1990's2 (6.25)18.2507
2000's15 (46.88)29.6817
2010's13 (40.63)24.3611
2020's1 (3.13)2.80

Authors

AuthorsStudies
Liu, GT; Wang, BE; Wang, YW; Zhang, TM1
Liu, Y; Wang, B; Xie, P1
Ni, KY; Zhang, GQ1
Guo, DA; Li, YY; Ren, H; Wang, CS; Ye, G1
Chan, CL; Chan, K; Chui, SH; Ha, WY; Wong, DY; Wong, RN1
Cui, M; Guo, D; He, Y; Li, L; Yu, H; Zhang, G; Zhang, J1
Fan, JY; Liu, YQ; Wang, ZP; Yuan, YJ1
Shen, LH; Wang, BY; Wang, CQ; Xie, XL; Yang, BJ; Yao, ZY; Yu, GR; Zhu, YL1
Cai, Y; Jia, J; Li, X; Liu, G; Wang, Y; Yu, C1
Ding, M; Guo, ZX; Ye, TX; Yuan, YJ; Zhao, GR1
Guo, YX; Wang, H; Wang, LX; Xiao, HB; Xiu, ZL; Zhang, DJ1
Bi, KS; Chen, XH; Guo, XR; Zhang, WT1
Gu, M; Ouyang, F; Su, Z; Wang, X1
Ding, M; Yuan, YJ1
Li, M; Lü, XY; Weng, MW1
Cui, Y; Li, Y; Shi, W; Xia, Z; Yang, M; Zhao, X1
Gu, M; Janson, JC; Su, ZG1
Hong, D; Wu, L; Yang, J; Yang, X; Yu, J; Zeng, X1
Li, J; Wu, L; Yin, FX; Yuan, Y; Zhang, QL; Zhang, YJ1
Chen, XJ; Han, DE; He, JK; Li, N; Li, TT; Lu, Y; Yang, SY; Zhao, D1
Cui, Y; Jia, B; Li, Y; Qi, Y; Zhao, X1
Jin, Y; Liu, X; Wu, Y; Wu, Z1
Chu, L; Gao, YG; Ma, JJ; Wang, JY; Wang, N; Xie, Y; Zhang, FH; Zhang, JP; Zhang, Y; Zhang, YY1
Dai, M; Huang, B; Li, YB; Yuan, Y; Zhang, AJ; Zhou, L1
Chen, P; Hu, Y; Kong, W; Luo, H; Wan, L; Wu, X; Yang, M1
Gong, Z; Huang, Y; Lan, Y; Liu, Y; Lu, Y; Wang, A; Wang, Y; Xie, Y; Zheng, L1
Duan, J; Guan, H; Qian, D; Ren, H; Shang, E; Su, S; Zhang, W1
Bi, CQ; Chen, TL; Ge, FH; Ma, XP; Xiao, X1
Guo, Y; Hua, L; Liu, Z; Qin, W; Yang, Y; Zheng, X1
Cai, W; Chen, W; Hu, M; Liu, X; Ma, G; Tang, Z; Xin, X; Yang, P; Zhang, Y1
Chen, M; Chu, Y; Guo, Z; Huang, L; Li, W; Li, X; Luo, R; Polachi, N; Sun, H; Wang, X; Yan, X; Yang, L; Zhou, H1
Jia, P; Li, Y; Liu, Y; Long, K; Sun, T; Wang, C; Wang, S; Yang, Y; Zhang, H; Zhao, Y; Zheng, X; Zhi, W; Zhou, J1

Other Studies

32 other study(ies) available for protocatechualdehyde and 3,4-dihydroxyphenyllactic acid

ArticleYear
Protective action of seven natural phenolic compounds against peroxidative damage to biomembranes.
    Biochemical pharmacology, 1992, Jan-22, Volume: 43, Issue:2

    Topics: Animals; Benzaldehydes; Caffeic Acids; Catechols; Cinnamates; Depsides; Erythrocyte Membrane; Hydroxybenzoates; Lactates; Lipid Peroxidation; Liver; Male; Microscopy, Electron, Scanning; Microsomes, Liver; Rats; Rats, Inbred Strains; Rosmarinic Acid

1992
[Evaluation of radix Salviae Miltiorrhizae and its preparation].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 1990, Volume: 15, Issue:3

    Topics: Abietanes; Benzaldehydes; Catechols; Chromatography, Thin Layer; Densitometry; Drug Combinations; Drugs, Chinese Herbal; Lactates; Phenanthrenes; Phenanthrolines; Plant Extracts; Salvia miltiorrhiza; Tablets

1990
[Reversed phase HPLC determination of three components in Salvia miltiorrhiza injections].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1988, Volume: 23, Issue:4

    Topics: Anticoagulants; Benzaldehydes; Catechols; Chromatography, High Pressure Liquid; Drug Combinations; Drugs, Chinese Herbal; Hydroxybenzoates; Injections; Lactates; Phenanthrolines; Plant Extracts; Salvia miltiorrhiza

1988
Simultaneous determination and pharmacokinetic studies on (3,4-Dihydroxyphenyl)-lactic acid and protocatechuic aldehyde in rat serum after oral administration of Radix Salviae miltiorrhizae extract.
    Journal of chromatographic science, 2003, Volume: 41, Issue:6

    Topics: Administration, Oral; Animals; Benzaldehydes; Calibration; Catechols; Drugs, Chinese Herbal; Lactates; Plant Extracts; Rats; Reproducibility of Results; Salvia miltiorrhiza; Sensitivity and Specificity

2003
Protective effects of Danshensu from the aqueous extract of Salvia miltiorrhiza (Danshen) against homocysteine-induced endothelial dysfunction.
    Life sciences, 2004, Nov-12, Volume: 75, Issue:26

    Topics: Benzaldehydes; Catechin; Catechols; Cell Survival; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Endothelial Cells; Homocysteine; Humans; Hydroxybenzoates; Lactates; Salvia miltiorrhiza; Spectrometry, Mass, Electrospray Ionization; Umbilical Veins

2004
Metabolic studies on the total phenolic acids from the roots of Salvia miltiorrhiza in rats.
    Biomedical chromatography : BMC, 2005, Volume: 19, Issue:1

    Topics: Animals; Benzaldehydes; Caffeic Acids; Catechols; Chromatography, High Pressure Liquid; Cinnamates; Coumaric Acids; Feces; Hydroxybenzoates; Lactates; Male; Plant Roots; Rats; Rats, Sprague-Dawley; Salvia miltiorrhiza; Spectrophotometry, Ultraviolet

2005
[Study on adsorption of danshen water-soluble compounds with macroporous resin D301].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2004, Volume: 29, Issue:9

    Topics: Adsorption; Anion Exchange Resins; Benzaldehydes; Catechols; Chromatography, High Pressure Liquid; Lactates; Plants, Medicinal; Salvia miltiorrhiza; Technology, Pharmaceutical

2004
[Effect of danshensu, protocatechualdehyde and danshen injection on calcium ion concentration in cytoplasm of human erythrocytes].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2004, Volume: 29, Issue:10

    Topics: Adult; Benzaldehydes; Calcium; Catechols; Cytoplasm; Drug Synergism; Drugs, Chinese Herbal; Erythrocytes; Female; Humans; Injections; Lactates; Male; Middle Aged; Plants, Medicinal; Salvia miltiorrhiza

2004
Simultaneous determination of six phenolic constituents of danshen in human serum using liquid chromatography/tandem mass spectrometry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2005, Jun-05, Volume: 820, Issue:1

    Topics: Benzaldehydes; Benzofurans; Caffeic Acids; Catechols; Chromatography, Liquid; Cinnamates; Depsides; Drug Stability; Drugs, Chinese Herbal; Humans; Lactates; Phenols; Reproducibility of Results; Rosmarinic Acid; Salvia miltiorrhiza; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization

2005
Aqueous extract of Salvia miltiorrhiza attenuates increased endothelial permeability induced by tumor necrosis factor-alpha.
    International immunopharmacology, 2005, Volume: 5, Issue:11

    Topics: Benzaldehydes; Benzofurans; Cadherins; Capillary Permeability; Catechols; Cells, Cultured; Endothelial Cells; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Gene Expression; Humans; Lactates; Plant Extracts; Salvia miltiorrhiza; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A

2005
Hydrolytic kinetics of lithospermic acid B extracted from roots of Salvia miltiorrhiza.
    Journal of pharmaceutical and biomedical analysis, 2007, Jan-17, Volume: 43, Issue:2

    Topics: Benzaldehydes; Benzofurans; Catechols; Chromatography, High Pressure Liquid; Depsides; Drug Stability; Drugs, Chinese Herbal; Half-Life; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Lactates; Mass Spectrometry; Models, Chemical; Molecular Structure; Plant Roots; Reference Standards; Salvia miltiorrhiza; Solutions; Spectrophotometry, Ultraviolet; Temperature

2007
[Determination of danshensu and protocatechuic aldehyde in Guanxinning injection powder by RP-HPLC].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2006, Volume: 31, Issue:16

    Topics: Benzaldehydes; Catechols; Chromatography, High Pressure Liquid; Drug Combinations; Drugs, Chinese Herbal; Injections; Lactates; Ligusticum; Plants, Medicinal; Powders; Quality Control; Reproducibility of Results; Salvia miltiorrhiza

2006
One-step separation and purification of 3,4-dihydroxyphenyllactic acid, salvianolic acid B and protocatechualdehyde from Salvia miltiorrhiza Bunge by high-speed counter-current chromatography.
    Journal of chromatography. A, 2007, Jan-26, Volume: 1140, Issue:1-2

    Topics: Benzaldehydes; Benzofurans; Catechols; Chromatography, High Pressure Liquid; Countercurrent Distribution; Lactates; Salvia miltiorrhiza

2007
Study on the mechanisms of an extract of Salvia miltiorrhiza on the regulation of permeability of endothelial cells exposed to tumour necrosis factor-alpha.
    The Journal of pharmacy and pharmacology, 2007, Volume: 59, Issue:7

    Topics: Adherens Junctions; Analysis of Variance; Benzaldehydes; Benzofurans; beta Catenin; Cadherins; Catechols; Cell Membrane Permeability; Cells, Cultured; Chromatography, High Pressure Liquid; Endothelial Cells; Enzyme Activation; Fluorescent Antibody Technique; Humans; Lactates; Phosphorylation; Phosphotyrosine; Plant Extracts; Salvia miltiorrhiza; Tumor Necrosis Factor-alpha; Umbilical Veins; Vascular Endothelial Growth Factor A

2007
[Inhibition effects of constituents of Radix Salviae Miltiorrhizae on proliferation and procollagen transcription of dermal fibroblasts in systemic sclerosis].
    Zhonghua yi xue za zhi, 2007, Sep-11, Volume: 87, Issue:34

    Topics: Abietanes; Benzaldehydes; Catechols; Cell Proliferation; Cells, Cultured; Collagen Type I; Collagen Type III; Drugs, Chinese Herbal; Female; Fibroblasts; Humans; Lactates; Male; Phenanthrenes; Plant Extracts; Procollagen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Salvia miltiorrhiza; Scleroderma, Systemic; Transcription, Genetic

2007
[Separation of water-soluble active components in Salvia miltiorrhiza bge. f. alba using capillary zone electrophoresis].
    Se pu = Chinese journal of chromatography, 2007, Volume: 25, Issue:5

    Topics: Benzaldehydes; Catechols; Electrophoresis, Capillary; Hydrogen-Ion Concentration; Hydroxybenzoates; Lactates; Salvia miltiorrhiza; Solubility; Water

2007
One-step purification of 3,4-dihydroxyphenyllactic acid, salvianolic acid B, and protocatechualdehyde from Salvia miltiorrhiza Bunge by isocratic stepwise hydrogen bond adsorption chromatography on cross-linked 12% agarose.
    Journal of chromatographic science, 2008, Volume: 46, Issue:2

    Topics: Adsorption; Benzaldehydes; Benzofurans; Catechols; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Hydrogen Bonding; Lactates; Salvia miltiorrhiza; Sepharose

2008
Effect of Guanxin No.2 decoction on gene expression in different areas of the myocardial infarcted heart of rats using microarray technology.
    The Journal of pharmacy and pharmacology, 2009, Volume: 61, Issue:2

    Topics: Animals; Benzaldehydes; Benzoates; Benzofurans; Bridged-Ring Compounds; Cardiotonic Agents; Carthamus tinctorius; Catechols; Chalcone; Coumaric Acids; Dalbergia; Drugs, Chinese Herbal; Gene Expression; Gene Expression Profiling; Glucosides; Heart Ventricles; Hydroxybenzoates; Lactates; Ligusticum; Male; Monoterpenes; Myocardial Infarction; Oligonucleotide Array Sequence Analysis; Paeonia; Plant Extracts; Quinones; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Salvia miltiorrhiza

2009
Pharmacokinetics of phenolic compounds of Danshen extract in rat blood and brain by microdialysis sampling.
    Journal of ethnopharmacology, 2011, Jun-14, Volume: 136, Issue:1

    Topics: Animals; Benzaldehydes; Benzofurans; Blood-Brain Barrier; Catechols; Drugs, Chinese Herbal; Hydroxybenzoates; Lactates; Male; Microdialysis; Rats; Rats, Sprague-Dawley; Salvia miltiorrhiza

2011
Simultaneous determination of six phenolic constituents of Danshen injection in rat plasma by LC-ESI-MS and its application to a pharmacokinetic study.
    European journal of mass spectrometry (Chichester, England), 2011, Volume: 17, Issue:4

    Topics: Animals; Benzaldehydes; Benzofurans; Caffeic Acids; Catechols; Chromatography, High Pressure Liquid; Chromatography, Liquid; Cinnamates; Depsides; Drug Stability; Drugs, Chinese Herbal; Injections, Intravenous; Lactates; Liquid-Liquid Extraction; Male; Mass Spectrometry; Plant Preparations; Rats; Reference Standards; Rosmarinic Acid; Salvia miltiorrhiza; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization

2011
[Capillary electrophoresis with field-enhanced stacking for determination of water-soluble active principles in Salvia miltiorrhiza var. miltiorrhiza f. alba].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2011, Volume: 36, Issue:11

    Topics: Benzaldehydes; Benzofurans; Catechols; Cinnamates; Depsides; Electrophoresis, Capillary; Hydroxybenzoates; Lactates; Plant Extracts; Quality Control; Rosmarinic Acid; Salvia miltiorrhiza; Sensitivity and Specificity; Solubility; Water

2011
Near infrared spectroscopy in combination with chemometrics as a process analytical technology (PAT) tool for on-line quantitative monitoring of alcohol precipitation.
    Journal of pharmaceutical and biomedical analysis, 2013, Apr-15, Volume: 77

    Topics: Benzaldehydes; Benzofurans; Catechols; Chalcone; Chemical Precipitation; Drugs, Chinese Herbal; Ethanol; Lactates; Least-Squares Analysis; Microfluidic Analytical Techniques; Online Systems; Quinones; Spectroscopy, Near-Infrared; Support Vector Machine

2013
Salvia miltiorrhiza (Danshen) injection ameliorates iron overload-induced cardiac damage in mice.
    Planta medica, 2013, Volume: 79, Issue:9

    Topics: Animals; Benzaldehydes; Benzofurans; Catechols; Chromatography, High Pressure Liquid; Creatine Kinase; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Glutathione Peroxidase; Heart; Injections, Intraperitoneal; Iron Overload; L-Lactate Dehydrogenase; Lactates; Male; Medicine, Chinese Traditional; Mice; Myocardium; Phenanthrolines; Salvia miltiorrhiza; Superoxide Dismutase

2013
Study of the in vitro-in vivo correlation of Danshensu and protocatechuic aldehyde in a two-step release system.
    Journal of Asian natural products research, 2015, Volume: 17, Issue:4

    Topics: Administration, Oral; Benzaldehydes; Catechols; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; In Vitro Techniques; Lactates; Molecular Structure; Osmosis; Salvia miltiorrhiza

2015
Quality evaluation of Salvia miltiorrhiza Bge. by ultra high performance liquid chromatography with photodiode array detection and chemical fingerprinting coupled with chemometric analysis.
    Journal of separation science, 2015, Volume: 38, Issue:9

    Topics: Benzaldehydes; Benzofurans; Caffeic Acids; Catechols; Chromatography, High Pressure Liquid; Cinnamates; Depsides; Lactates; Least-Squares Analysis; Principal Component Analysis; Rosmarinic Acid; Salvia miltiorrhiza

2015
A UPLC-MS/MS method for simultaneous determination of danshensu, protocatechuic aldehyde, rosmarinic acid, and ligustrazine in rat plasma, and its application to pharmacokinetic studies of Shenxiong glucose injection in rats.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2015, Aug-01, Volume: 997

    Topics: Animals; Benzaldehydes; Catechols; Chromatography, High Pressure Liquid; Cinnamates; Depsides; Drugs, Chinese Herbal; Female; Injections, Intravenous; Lactates; Limit of Detection; Linear Models; Male; Pyrazines; Rats, Sprague-Dawley; Reproducibility of Results; Rosmarinic Acid; Tandem Mass Spectrometry

2015
Simultaneous determination of tanshinones and polyphenolics in rat plasma by UPLC-MS/MS and its application to the pharmacokinetic interaction between them.
    Drug testing and analysis, 2016, Volume: 8, Issue:7

    Topics: Abietanes; Animals; Benzaldehydes; Benzofurans; Catechols; Chromatography, High Pressure Liquid; Cinnamates; Depsides; Lactates; Limit of Detection; Liquid-Liquid Extraction; Male; Phenanthrenes; Polyphenols; Rats, Sprague-Dawley; Rosmarinic Acid; Tandem Mass Spectrometry

2016
[Fingerprint and Simultaneous Determination of Multi-components in Water-soluble Components of Salvia miltiorrhiza in Miao Autonomous County of Songtao, Guizhou].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2015, Volume: 38, Issue:3

    Topics: Benzaldehydes; Benzofurans; Caffeic Acids; Catechols; Chromatography, High Pressure Liquid; Cinnamates; Depsides; Drugs, Chinese Herbal; Lactates; Phytochemicals; Quality Control; Rosmarinic Acid; Salvia miltiorrhiza; Water

2015
Quantitatively metabolic profiles of salvianolic acids in rats after gastric-administration of Salvia miltiorrhiza extract.
    Fitoterapia, 2016, Volume: 113

    Topics: Alkenes; Animals; Benzaldehydes; Caffeic Acids; Catechols; Drug Stability; Drugs, Chinese Herbal; Hydroxybenzoates; Lactates; Male; Metabolome; Molecular Structure; Polyphenols; Rats; Rats, Wistar; Salvia miltiorrhiza

2016
Inhibition of Human UGT1A1-Mediated Bilirubin Glucuronidation by Polyphenolic Acids Impact Safety of Popular Salvianolic Acid A/B-Containing Drugs and Herbal Products.
    Molecular pharmaceutics, 2017, 09-05, Volume: 14, Issue:9

    Topics: Benzaldehydes; Benzofurans; Bilirubin; Caffeic Acids; Catechols; Cinnamates; Depsides; Glucuronosyltransferase; Humans; Kinetics; Lactates; Microsomes, Liver; Polyphenols; Rosmarinic Acid; Salvia miltiorrhiza

2017
Simultaneous determination and pharmacokinetics of danshensu, protocatechuic aldehyde, 4-hydroxy-3-methyloxyphenyl lactic acid and protocatechuic acid in human plasma by LC-MS/MS after oral administration of Compound Danshen Dripping Pills.
    Journal of pharmaceutical and biomedical analysis, 2017, Oct-25, Volume: 145

    Topics: Administration, Oral; Benzaldehydes; Camphanes; Catechols; China; Drugs, Chinese Herbal; Humans; Hydroxybenzoates; Lactates; Lactic Acid; Panax notoginseng; Salvia miltiorrhiza; Tandem Mass Spectrometry

2017
Guanxining injection alleviates fibrosis in heart failure mice and regulates SLC7A11/GPX4 axis.
    Journal of ethnopharmacology, 2023, Jun-28, Volume: 310

    Topics: Animals; Chromatography, Liquid; Drugs, Chinese Herbal; Fibrosis; Glycine; Heart Failure; Mice; Rosmarinic Acid; Salvia miltiorrhiza; Tandem Mass Spectrometry; Vanillic Acid

2023