prostaglandin-d2 and lanthanum-chloride

prostaglandin-d2 has been researched along with lanthanum-chloride* in 1 studies

Other Studies

1 other study(ies) available for prostaglandin-d2 and lanthanum-chloride

Article	Year
On the mechanism of action of sodium orthovanadate in inducing histamine release from rat peritoneal mast cells. International archives of allergy and immunology, 1993, Volume: 101, Issue:4 Sodium orthovanadate produced a dose-dependent release of histamine and prostaglandin D2 from rat peritoneal mast cells. The release of histamine was selectively inhibited by the anion channel blockers SITS and DIDS, and by theophylline and dibutyryl cyclic-AMP, but was unaffected by disodium cromoglycate and lanthanum ions. Unlike IgE-directed ligands, vanadate did not produce any change in the intracellular concentration of cyclic-AMP but did promote a substantial uptake of calcium-45 from the incubation medium. This effect paralleled the release of histamine. These results are discussed in terms of the possible mode of action of vanadate. Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Anions; Calcium; Cyclic AMP; Depression, Chemical; Female; Histamine Release; Ion Channels; Lanthanum; Male; Mast Cells; Ouabain; Peritoneal Cavity; Prostaglandin D2; Rats; Rats, Sprague-Dawley; Theophylline; Vanadates	1993

Article

Year

On the mechanism of action of sodium orthovanadate in inducing histamine release from rat peritoneal mast cells.

International archives of allergy and immunology, 1993, Volume: 101, Issue:4

Sodium orthovanadate produced a dose-dependent release of histamine and prostaglandin D2 from rat peritoneal mast cells. The release of histamine was selectively inhibited by the anion channel blockers SITS and DIDS, and by theophylline and dibutyryl cyclic-AMP, but was unaffected by disodium cromoglycate and lanthanum ions. Unlike IgE-directed ligands, vanadate did not produce any change in the intracellular concentration of cyclic-AMP but did promote a substantial uptake of calcium-45 from the incubation medium. This effect paralleled the release of histamine. These results are discussed in terms of the possible mode of action of vanadate.

Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Anions; Calcium; Cyclic AMP; Depression, Chemical; Female; Histamine Release; Ion Channels; Lanthanum; Male; Mast Cells; Ouabain; Peritoneal Cavity; Prostaglandin D2; Rats; Rats, Sprague-Dawley; Theophylline; Vanadates

1993