prostaglandin-d2 and azatadine

prostaglandin-d2 has been researched along with azatadine* in 1 studies

Reviews

1 review(s) available for prostaglandin-d2 and azatadine

ArticleYear
The effects of antihistamines beyond H1 antagonism in allergic inflammation.
    The Journal of allergy and clinical immunology, 1990, Volume: 86, Issue:6 Pt 2

    Antigen and cold dry air were used to challenge the upper and lower airways, skin, and conjunctiva. In each of these four systems an immediate and late-phase reaction to antigen is well characterized. Although the pattern of mediator release is different in these four areas, the degree of infiltration of basophils and eosinophils in the late-phase reaction appears to be constant. Of a number of drugs that can influence these mediators and cell responses, the steroids represent a typical mode of action. Steroids block the late-phase response and ablate the eosinophil and basophil infiltration. Although the effects of antihistamines appear to be similar, they do not appear to be caused by H1 antagonism; the mechanism of their action is unknown. This discussion will focus on these non-H1 antagonist effects of antihistamines in four challenge models, particularly the upper airways and skin.

    Topics: Benzhydryl Compounds; Cetirizine; Cyproheptadine; Dermatitis, Atopic; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Hydroxyzine; Prostaglandin D2; Rhinitis, Allergic, Seasonal; SRS-A; Terfenadine

1990

Trials

1 trial(s) available for prostaglandin-d2 and azatadine

ArticleYear
The effects of antihistamines beyond H1 antagonism in allergic inflammation.
    The Journal of allergy and clinical immunology, 1990, Volume: 86, Issue:6 Pt 2

    Antigen and cold dry air were used to challenge the upper and lower airways, skin, and conjunctiva. In each of these four systems an immediate and late-phase reaction to antigen is well characterized. Although the pattern of mediator release is different in these four areas, the degree of infiltration of basophils and eosinophils in the late-phase reaction appears to be constant. Of a number of drugs that can influence these mediators and cell responses, the steroids represent a typical mode of action. Steroids block the late-phase response and ablate the eosinophil and basophil infiltration. Although the effects of antihistamines appear to be similar, they do not appear to be caused by H1 antagonism; the mechanism of their action is unknown. This discussion will focus on these non-H1 antagonist effects of antihistamines in four challenge models, particularly the upper airways and skin.

    Topics: Benzhydryl Compounds; Cetirizine; Cyproheptadine; Dermatitis, Atopic; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Hydroxyzine; Prostaglandin D2; Rhinitis, Allergic, Seasonal; SRS-A; Terfenadine

1990