Compounds > prorenone
Page last updated: 2024-09-05

prorenone and aldosterone

prorenone has been researched along with aldosterone in 7 studies

Compound Research Comparison

Studies
(prorenone)		Trials
(prorenone)		Recent Studies (post-2010)
(prorenone)		Studies
(aldosterone)		Trials
(aldosterone)		Recent Studies (post-2010) (aldosterone)
90025,3331,5174,169

Protein Interaction Comparison

ProteinTaxonomyprorenone (IC50)aldosterone (IC50)
Mineralocorticoid receptor Homo sapiens (human)0.0048
Mineralocorticoid receptorRattus norvegicus (Norway rat)0.043

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19907 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Claire, M; Corvol, P; Michaud, A; Rafestin-Oblin, ME; Roth-Meyer, C1
Emadian, SM; Luttge, WG1
Capron, MH; Delarue, C; Leboulenger, F; Netchitailo, P; Perroteau, I; Vaudry, H2
Gomez-Sanchez, EP1
Claire, M; Corvol, P; Gäggeler, HP; Geering, K; Rafestin-Oblin, ME; Rossier, BC1
Claire, M; Corvol, P; Geering, K; Oblin, ME; Rossier, B1

Reviews

1 review(s) available for prorenone and aldosterone

ArticleYear
Mechanism of the antimineralocorticoid effects of spirolactones.
    Kidney international, 1981, Volume: 20, Issue:1

    Topics: Aldosterone; Animals; Anura; Canrenoic Acid; Canrenone; Cattle; Guinea Pigs; Humans; Male; Mineralocorticoid Receptor Antagonists; Rats; Receptors, Steroid; Spironolactone; Veratrum Alkaloids

1981

Other Studies

6 other study(ies) available for prorenone and aldosterone

ArticleYear
Mechanism of action of a new antialdosterone compound, prorenone.
    Endocrinology, 1979, Volume: 104, Issue:4

    Topics: Aldosterone; Animals; Binding, Competitive; Cell Nucleus; Dexamethasone; Dihydrotestosterone; Kidney; Kinetics; Male; Mineralocorticoid Receptor Antagonists; Prostate; Rats; Receptors, Androgen; Receptors, Glucocorticoid; Spironolactone

1979
Further chemical differentiation of type I and type II adrenocorticosteroid receptors in mouse brain cytosol: evidence for a new class of glucocorticoid receptors.
    Brain research, 1988, Jun-21, Volume: 453, Issue:1-2

    Topics: Aldosterone; Androstanols; Animals; Brain Chemistry; Cytosol; Dextrans; Dithionitrobenzoic Acid; Female; Mice; Potassium Chloride; Receptors, Glucocorticoid; Spironolactone; Subcellular Fractions

1988
Relative inhibitory potency of five mineralocorticoid antagonists on aldosterone biosynthesis in vitro.
    Biochemical pharmacology, 1985, Jan-15, Volume: 34, Issue:2

    Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; In Vitro Techniques; Male; Mineralocorticoid Receptor Antagonists; Pregnenes; Ranidae; Spironolactone; Structure-Activity Relationship; Veratrum Alkaloids

1985
Intracerebroventricular infusion of aldosterone induces hypertension in rats.
    Endocrinology, 1986, Volume: 118, Issue:2

    Topics: Aldosterone; Animals; Brain; Cerebral Ventricles; Hypertension; Male; Mineralocorticoid Receptor Antagonists; Rats; Rats, Inbred Strains; Spironolactone

1986
Binding and antimineralocorticoid activities of spirolactones in toad bladder.
    The American journal of physiology, 1983, Volume: 244, Issue:1

    Topics: Aldosterone; Animals; Binding, Competitive; Biological Transport; Bufo marinus; Female; In Vitro Techniques; Male; Mineralocorticoid Receptor Antagonists; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Receptors, Steroid; Sodium; Spironolactone; Urinary Bladder

1983
[Direct action of mineralocorticoid antagonists on biosynthesis of aldosterone: comparative activities of several new compounds].
    Canadian journal of physiology and pharmacology, 1983, Volume: 61, Issue:1

    Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; In Vitro Techniques; Male; Mineralocorticoid Receptor Antagonists; Pregnenes; Ranidae; Receptors, Mineralocorticoid; Receptors, Steroid; Spironolactone; Veratrum Alkaloids

1983