propylthiouracil has been researched along with 1-3-dibromo-5-5-dimethylhydantoin* in 2 studies
2 other study(ies) available for propylthiouracil and 1-3-dibromo-5-5-dimethylhydantoin
| Article | Year |
|---|---|
1,3-Dibromo-5,5-dimethylhydantoin (DBH) as oxidant and precipitant for drug identification according to PH. EUR Analytical methods of pharmacopoeias with DBH in respect of environmental and economical concern, Part 15(1).
Elemental bromine serves as oxidant for the identification of propylthiouracil, 2-thiouracil and sulphur according to PH. EUR. 2002. Phenol is identified according to PH. EUR. 2002 with bromine water as the sparingly water-soluble 2,4,4,6-tetrabromo-2,5-cyclohexadiene-1-one. These tests can be performed better using 1,3-dibromo-5,5-dimethylhydantoin (DBH). Topics: Bromine; Europe; Hydantoins; Indicators and Reagents; Oxidants; Pharmacopoeias as Topic; Phenol; Propylthiouracil; Sulfur; Thiouracil | 2002 |
Determination of propylthiouracil using 1,3-dibromo-5,5-dimethylhydantoin (DBH): analytical methods of pharmacopeias with DBH in respect to environmental and economical concern: part 9.
USP 2000 [The United States Pharmacopeia, Rockville USA, 24th ed., 2000, pp. 1436] and PH. EUR. 1997 [European Pharmacopoeia, third ed., Council of Europe, Strasbourg, 1997, p. 1401] determine propylthiouracil using neutralization titration, whereby 0.1 M silver nitrate and twice boiling is necessary. With the application of 1,3-dibromo-5,5-dimethylhydantoin (DBH), the assay of propylthiouracil can be performed easily, faster and friendlier to environment. A mean deviation of 0.03% and a relative standard deviation of 0.3% are obtained. 5-Bromo-6-propyluracil is formed, when propylthiouracil is determined with DBH. Topics: Antithyroid Agents; Environmental Pollution; Hydantoins; Hydrogen-Ion Concentration; Indicators and Reagents; Iodine; Pharmacopoeias as Topic; Propylthiouracil; Silver Nitrate; Solutions | 2002 |