Page last updated: 2024-08-18

propylparaben and butylparaben

propylparaben has been researched along with butylparaben in 157 studies

Research

Studies (157)

TimeframeStudies, this research(%)All Research%
pre-19908 (5.10)18.7374
1990's16 (10.19)18.2507
2000's33 (21.02)29.6817
2010's72 (45.86)24.3611
2020's28 (17.83)2.80

Authors

AuthorsStudies
Li, HY; Li, KL; Peng, DR; Song, BL; Zhang, GH; Zhang, J; Zhao, YQ1
Li, HY; Peng, DR; Song, BL1
Hjorth, N; Menné, T1
Sies, H; Wefers, H1
Hashida, M; Higaki, K; Komatsu, H; Miyagawa, K; Okamoto, H; Sezaki, H1
Hashida, M; Komatsu, H; Miyagawa, K; Okamoto, H; Sezaki, H1
Akamizu, H; Aoki, Y; Eto, R; Inai, K; Nishida, T; Tokuoka, S1
Eklund, T; Nes, IF1
Komatsu, H1
Fujimori, K; Inoue, K; Nakazawa, K; Takanaka, A1
de Kruijf, N; Rastogi, SC; Schouten, A; Weijland, JW1
Kim, B; Kim, DH; Kim, HS; Kobashi, K; Sohng, IS1
Bando, H; Hashida, M; Koyama, Y; Sezaki, H; Takakura, Y; Yamashita, F1
Adebayo, CO; Adegoke, GO1
Bando, H; Hashida, M; Kitagawa, S; Koyama, Y; Takakura, Y; Yamashita, F1
Akatsu, S; Fukahori, M; Sato, H; Yotsuyanagi, T1
Bando, H; Hashida, M; Mohri, S; Takakura, Y; Yamashita, F1
Farber, GA1
Ashby, J; Odum, J; Parker, J; Routledge, EJ; Sumpter, JP1
Bando, H; Hashida, M; Lim, CW; Seko, N; Yamashita, F1
Newton, JM; Tomer, G1
Curran, TM; Ma, Y; Marquis, RE; Reidmiller, JS; Rutherford, GC1
Bettini, R; Caira, MR; Donini, C; Gazzaniga, A; Giordano, F; Grant, DJ; Zhang, GG1
Harris, D; Spangler, M1
Bjerregaard, P; Christiansen, LB; Korsgaard, B; Pedersen, KL; Pedersen, SN1
Che, JH; Kang, KS; Kim, TW; Lee, YS; Li, GX; Ryu, DY1
Oishi, S2
Blumberg, B; Cao, J; Grün, F; Hemmati, D; Tabb, MM; Venkatesan, RN; Zhou, C1
Cho, SD; Kang, KS; Lee, YS1
Belgaied, JE; Trabelsi, H1
Akomeah, F; Brown, MB; Martin, GP; Nazir, T1
Daston, GP1
Harvey, PW1
Alslev, B; Bjerregaard, P; Korsgaard, B1
Avila, ME; Castell, A; Franco, Y; Hernández, A; Jaimez, R; Lemini, C1
Bartlett, A; Brown, MB; Forbes, B; Marriott, C; Nanayakkara, GR; Whitfield, PJ1
Gallegos, MT; Krell, T; Ramos, JL; Terán, W1
Lee, MR; Li, ZG; Lin, CY; Tsai, TF1
Akomeah, FK; Brown, MB; Martin, GP2
Aleksic, M; Basketter, DA; Dell, A; Morris, HR; Panico, M; Pease, CK1
Feng, Y; Grant, DJ; Sun, CC1
Akomeah, FK; Brown, MB; Martin, GP; Muddle, AG1
Chang, B; Ge, J; Liang, Y1
Andersson, AM; Janjua, NR; Kongshoj, B; Mortensen, GK; Skakkebaek, NE; Wulf, HC1
Berard, M; El Hussein, S; Humbert, P; Makki, S; Muret, P1
Ackermann, C; Fate, G; Jewell, C; Payne, NA; Prusakiewicz, JJ; Voorman, R; Williams, FM1
Guan, Y; Qian, L; Xiao, H1
Hirai, N; Hirata, Y; Kagami, Y; Kitani, C; Koshio, M; Nakamura, H; Nakamura, Y; Sekizawa, J; Tatarazako, N; Uchida, M; Watanabe, M; Yamamoto, H1
Katsuki, S; Moriguchi, S; Nakamura, Y; Sekizawa, J; Watanabe, M; Yamamoto, H1
Carthew, P; Daston, GP; Hoberman, AM; Leazer, T; Loretz, L; Mann, P; Re, T; Schreur, DK1
Axelstad, M; Boberg, J; Frederiksen, H; Hansen, PR; Hass, U; Nellemann, C; Taxvig, C; Vinggaard, AM1
Gryglik, D; Lach, M; Miller, JS1
Ge, H; Hou, TT; Sun, JJ; Yang, H1
deCatanzaro, D; Shaw, J1
Frenning, G; Larsson, A; Norder, O; Tajarobi, F; Unga, J1
Bishop, AM; Calafat, AM; Needham, LL; Wong, LY; Ye, X1
Choi, KC; Jeung, EB; Vo, TT; Yoo, YM1
Beltran, A; Borrull, F; Cormack, PA; Marcé, RM1
Chu, Q; Wang, W; Wang, Y; Ye, J; Zhang, J1
Larsson, A; Viridén, A; Wittgren, B1
Gye, MC; Lee, JE; Nah, WH; Oh, YS; Park, CJ1
Billen, J; Denayer, J; Desmet, G; Liekens, A; Ritchie, H; Sherant, R1
Aoki, K; Egawa, M; Hosokawa, T; Kurasaki, M; Saito, T; Sun, Y1
Braun, JM; Calafat, AM; Correia, KF; Ehrlich, S; Ford, J; Hauser, R; Keller, M; Meeker, JD; Smith, KW; Williams, PL; Ye, X1
Darbre, PD; Khanna, S1
Han, HJ; Jeong, HG; Jeong, TC; Jin, SW; Kang, W; Khanal, T; Kim, DH; Kim, HG; Lee, DH; Noh, K; Park, S; Shim, E; Yeo, HK1
Banks, TT; Black, SR; Blystone, CR; Brown, SS; Etheridge, AS; Fennell, TR; Mathews, JM; Patel, PR; Snyder, RW; Waidyanatha, S1
Borgie, M; Chahine, R; Dagher, Z; Greige-Gerges, H; Magdalou, J1
Tillett, T1
Aswal, VK; Bahadur, P; Ganguly, R; Khimani, M; Nath, S1
Kitamura, S; Kojima, H; Ohta, S; Takeuchi, S; Uramaru, N; Watanabe, Y1
Abu Amara, HM; Casadei, MA; Cerreto, F; Cesa, S; D'Auria, FD; Paolicelli, P; Simonetti, G1
Atheba, P; Drogui, P; Robert, D; Seyhi, B1
Gregoraszczuk, EŁ; Wróbel, A1
Ballesteros, L; Ballesteros, O; Cela, R; Navalón, A; Rodríguez, I; Vela-Soria, F; Zafra-Gómez, A1
Ali, EH; Elgoly, AH1
Bao, H; Guan, X; Huang, Y; Qiao, J; Sun, B; Wang, H; Zhang, J; Zhou, G1
Alam, MS; Kanai, Y; Kurohmaru, M; Ohsako, S1
Axelstad, M; Boberg, J; Christiansen, S; Hass, U; Isling, LK; Jacobsen, PR; Kortenkamp, A; Mandrup, KR; Taxvig, C; Vinggaard, AM1
Alam, MS; Kurohmaru, M1
Gregoraszczuk, EŁ; Wróbel, AM3
Chang, B; Ding, S; Dong, L; Du, Q; Li, Y; Qiao, P; Tang, N; Wang, C; Zhang, L; Zhang, M1
Darbre, PD; Dash, PR; Khanna, S1
Daghrir, R; Dimboukou-Mpira, A; Drogui, P; Seyhi, B1
Alshawabkeh, AN; Anzalota Del Toro, LV; Cordero, JF; Ferguson, KK; Meeker, JD; Watkins, DJ1
Dolenc, MS; Klopčič, I; Kolšek, K1
Ali, EH; Elgoly, AH; Hegazy, HG1
Campbell, JL; Clewell, HJ; Yoon, M1
Afonso, AM; Ayala, JH; Martínez-Benito, C; Pasán, J; Pino, V; Rocío-Bautista, P; Ruiz-Pérez, C1
Mallick, S; Pattnaik, S; Rao, JV; Swain, K; Varun, T1
De Wael, K; Pilehvar, S; Rather, JA1
Angerer, J; Brüning, T; Dierkes, G; Koch, HM; Moos, RK1
Cherfan, J; Drugan, T; Gutleb, AC; Kiss, B; Loghin, F; Lupu, D; Pop, A2
Kirton, SB; Martin, GP; Murnane, D; Najib, ON; Sallam, AS1
Gao, MJ; Kuang, HX; Lv, JN; Meng, YH; Mi, YY; Wang, ZB; Yang, BY; Yang, CJ1
Arrebola, JP; Artacho-Cordón, F; Belhassen, H; Fernández, MF; Ghali, R; Hedhili, A; Jiménez-Díaz, I; Olea, N; Vela-Soria, F1
Axelstad, M; Boberg, J; Christiansen, S; Hass, U; Mandrup, K; Svingen, T; Vinggaard, AM1
Foster, WG; Furlong, HC; Guerra, MT; Kempinas, WG1
Kim, BH; Kim, S; Seo, JE1
Anselmo-Franci, JA; Borges, CS; Cucielo, MS; Foster, WG; Guerra, MT; Kempinas, WG; Leite, GA; Sanabria, M1
Chen, J; Chen, X; Hu, P; Kennedy, RC; Shen, CL; Zhang, J; Zhao, L1
Hu, Z; Ji, F; Mao, Q; Wang, Q; Wang, W; Yuan, S1
Bhardwaj, YK; Guin, JP; Varshney, L1
Ahn, C; Jeung, EB; Kang, HY; Lee, JH; Lee, M; Tran, DN1
Domingo, JL; Garcia, T; Gómez, M; Kumar, V; Prasad, R; Schreiber, E; Sirvent, JJ1
Chen, J; Heal, E; Hu, P; Overby, H; Shen, CL; Wang, S; Zhao, L1
Czarczyńska-Goślińska, B; Frankowski, R; Grześkowiak, T; Jeszka-Skowron, M; Zgoła-Grześkowiak, A1
Cieślak, M; Domeradzka-Gajda, K; Grobelny, J; Kozajda, A; Puchowicz, D; Ranoszek-Soliwoda, K; Roszak, J; Smok-Pieniążek, A; Spryszyńska, S; Stępnik, M; Tomaszewska, E1
Chen, HH; Jiang, JG; Shang, Y; Xu, XL1
Manzetti, S1
Bazer, FW; Lim, W; Song, G; Yang, C1
Abd El Aziz, SA; Abd-Rabo, MM; Badawy, MM; El Behairy, AM; Riad, MA1
Brown, SE; Fleischman, SM; Roy, MA; Sant, KE; Timme-Laragy, AR; Venezia, O; Zhao, L1
Li, H; Lu, J; Tu, Y; Yang, Z1
Kung, TA; Lee, SH; Wang, WH; Yang, TC1
Almeida, EA; Mansano, AS; Oliveira, TMA; Serrano, L; Silva, DC; Vieira, EM1
Lu, T; Manzetti, S1
Dighe, V; Maske, P; Vanage, G1
Endo, Y; Imai, Y; Kurohane, K; Matsuoka, T1
Glassey, J; Kizhedath, A; Wilkinson, S1
Juárez-Jiménez, B; López-Martínez, S; Maza-Márquez, P; Pesciaroli, C; Vílchez-Quero, JL; Zafra-Gómez, A1
Dogan, S; Erdogan, G; Erkaymaz, T; Sik, B; Simsek, T; Tongur, T; Unal, B1
Amagai, T; Hayashi, T; Makino, M; Miyake, Y; Nitta, S; Tokumura, M; Wang, Q; Yamaguchi, R1
Cho, YH; Choi, K; Kho, Y; Kim, JH; Kim, YJ; Lee, EH; Park, NY1
Fujita, KI; Murata, W; Ogita, A; Tanaka, T; Yamaguchi, Y; Yamauchi, K1
Fu, ML; Peng, H; Yang, JE; Yuan, B1
Dighe, V; Maske, P; Mote, C; Vanage, G1
Celichowski, G; Domeradzka-Gajda, K; Grobelny, J; Jeżak, K; Ranoszek-Soliwoda, K; Roszak, J; Smok-Pieniążek, A; Stępnik, M; Tomaszewska, E1
Jee, BC; Kim, JH1
Albores, A; Hernández-Melchor, D; Herrera-Cogco, E; López-Bayghen, B; López-Bayghen, E; López-Bello, E; López-Luna, A; Palafox-Gómez, C; Ramírez-Martínez, L1
Jeong, PS; Kang, HG; Kim, MJ; Kim, SU; Koo, DB; Lee, S; Nanjidsuren, T; Park, SH; Sim, BW; Son, HC; Song, BS1
Enrique, A; Martín, P; Milesi, V; Sbaraglini, ML; Talevi, A1
Ebrahimpour, K; Feizi, A; Hajizadeh, Y; Kiani Feizabadi, G1
Blystone, CR; Brix, A; Cunny, H; Hubbard, TD; McBride, S; McIntyre, BS; Roberts, GK; Shockley, K; Turner, KJ; Waidyanatha, S1
Andersson, AM; Axelstad, M; Boberg, J; Holmboe, SA; Johansen, M; Johansson, HKL; Olsen, GPM; Svingen, T1
Gogoi, P; Kalita, JC1
Feizi, A; Hajizadeh, Y; Kiani Feizabadi, G1
Alloro, M; Conte, A; Crescenzo, G; Lai, O; Merola, C; Perugini, M; Torelli, T1
Ali, S; Ara, C; Arshad, A; Batool, F; Butt, N; Shakir, HA1
Andersen, MS; Andersson, AM; Frederiksen, H; Grøntved, A; Højsager, FD; Jensen, TK; Juul, A; Kyhl, HB1
Hamdan, II; Khalil, EA; Mansour, RSH; Salem, MSH; Sallam, AA1
Bertolucci, C; Lucon-Xiccato, T; Merola, C; Perugini, M1
Bae, JS; Choi, YK; Kim, KB; Lee, BM; Lee, JD; Shin, CY; Shin, HC; Song, SW1
Baker, RC; Buchanan, RL; Ding, Q; Ge, C; Tikekar, RV1
Hyun, SA; Jang, S; Ka, M; Ko, MY; Lee, BS; Rho, J; Seo, JW1
Arockiaraj, J; Guru, A; Juliet, M; Lite, C1
Ball, AL; Franco, ME; Lavado, R; Solan, ME1
Andersson, AM; Beck, AL; Boye, H; Bräuner, EV; Frederiksen, H; Jensen, TK; Lim, YH; Uldbjerg, CS1
Chen, J; Hu, B; Liu, S; Shan, X; Wang, C; Wang, P; Wang, X1
Huan, C; Huo, W; Jia, Z; Liao, W; Mao, Z; Nie, L; Song, Y; Wang, C; Wang, J; Wang, L; Wang, M; Wei, D; Xu, Q1
Bae, ON; Choi, S; Gil, J; Kim, D; Kim, EH; Kim, W; Ko, Y; Park, HJ; Shin, Y1
Eghan, K; Kim, WK; Lee, S1

Reviews

1 review(s) available for propylparaben and butylparaben

ArticleYear
Using assessment criteria for pesticides to evaluate the endocrine disrupting potential of non-pesticide chemicals: Case butylparaben.
    Environment international, 2020, Volume: 144

    Topics: Cosmetics; Endocrine Disruptors; Parabens; Pesticides

2020

Trials

1 trial(s) available for propylparaben and butylparaben

ArticleYear
Systemic uptake of diethyl phthalate, dibutyl phthalate, and butyl paraben following whole-body topical application and reproductive and thyroid hormone levels in humans.
    Environmental science & technology, 2007, Aug-01, Volume: 41, Issue:15

    Topics: Administration, Topical; Adult; Dibutyl Phthalate; Gonadal Steroid Hormones; Humans; Hypothalamo-Hypophyseal System; Male; Parabens; Phthalic Acids; Pituitary-Adrenal System; Thyroid Hormones

2007

Other Studies

155 other study(ies) available for propylparaben and butylparaben

ArticleYear
Evaluation of the effect of butyl p-hydroxybenzoate on the proteolytic activity and membrane function of human spermatozoa.
    Journal of reproduction and fertility, 1991, Volume: 91, Issue:2

    Topics: Acrosin; Cell Membrane; Humans; Male; Parabens; Protease Inhibitors; Sperm Motility; Spermatozoa; Tosyllysine Chloromethyl Ketone

1991
In vitro spermicidal activity of parabens against human spermatozoa.
    Contraception, 1989, Volume: 39, Issue:3

    Topics: Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Male; Parabens; Sperm Motility; Spermatozoa

1989
Routine patch testing with paraben esters.
    Contact dermatitis, 1988, Volume: 19, Issue:3

    Topics: Female; Humans; Male; Middle Aged; Parabens; Patch Tests; Skin; Skin Tests

1988
Reactive oxygen species formed in vitro and in cells: role of thiols (GSH). Model studies with xanthine oxidase and horseradish peroxidase.
    Advances in experimental medicine and biology, 1986, Volume: 197

    Topics: Animals; Glutathione; Glutathione Disulfide; Horseradish Peroxidase; Kinetics; Liver; Luminescent Measurements; Parabens; Peroxidases; Rats; Vitamin K; Xanthine Oxidase

1986
Preservative activity and in vivo percutaneous penetration of butylparaben entrapped in liposomes.
    Chemical & pharmaceutical bulletin, 1986, Volume: 34, Issue:8

    Topics: Animals; Bacteria; Guinea Pigs; Liposomes; Parabens; Pharmaceutic Aids; Preservatives, Pharmaceutical; Skin Absorption

1986
Percutaneous absorption of butylparaben from liposomes in vitro.
    Chemical & pharmaceutical bulletin, 1986, Volume: 34, Issue:8

    Topics: Animals; Guinea Pigs; In Vitro Techniques; Liposomes; Male; Parabens; Skin Absorption

1986
Tumorigenicity study of butyl and isobutyl p-hydroxybenzoates administered orally to mice.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1985, Volume: 23, Issue:6

    Topics: Administration, Oral; Amyloidosis; Animals; Dose-Response Relationship, Drug; Female; Food Preservatives; Leukemia, Experimental; Male; Mice; Mice, Inbred ICR; Mutagenicity Tests; Neoplasms, Experimental; Parabens

1985
The effect of parabens on DNA, RNA and protein synthesis in Escherichia coli and Bacillus subtilis.
    The Journal of applied bacteriology, 1983, Volume: 54, Issue:2

    Topics: Bacillus subtilis; Bacterial Proteins; DNA, Bacterial; Escherichia coli; Parabens; RNA, Bacterial

1983
Percutaneous absorption of butylparaben in vitro. II. Effects of micellar trapping of the drug and percutaneous absorption of nonionic surfactants.
    Chemical & pharmaceutical bulletin, 1984, Volume: 32, Issue:9

    Topics: Animals; Guinea Pigs; In Vitro Techniques; Male; Micelles; Parabens; Skin Absorption; Surface-Active Agents

1984
Modulation by alkyl p-hydroxybenzoates of voltage- and ligand-gated channels in peripheral neuronal cells.
    Neuropharmacology, 1994, Volume: 33, Issue:7

    Topics: Acetylcholine; Adenosine Triphosphate; Animals; Barium; Ion Channel Gating; Ion Channels; Ligands; Neurons; Parabens; Patch-Clamp Techniques; PC12 Cells; Peripheral Nerves; Potassium Channels; Rats; Receptors, Nicotinic

1994
Contents of methyl-, ethyl-, propyl-, butyl- and benzylparaben in cosmetic products.
    Contact dermatitis, 1995, Volume: 32, Issue:1

    Topics: Chromatography, High Pressure Liquid; Cosmetics; Parabens; Product Surveillance, Postmarketing

1995
Sulfation of parabens and tyrosylpeptides by bacterial arylsulfate sulfotransferases.
    Biological & pharmaceutical bulletin, 1994, Volume: 17, Issue:10

    Topics: Animals; Arylsulfotransferase; Cholecystokinin; Endorphins; Enkephalin, Leucine; Eubacterium; Feces; Fungi; Haemophilus; Humans; Hydrogen-Ion Concentration; Hydroxybenzoates; Intestines; Klebsiella; Male; Mice; Naphthols; Parabens; Phenols; Rats; Staphylococcus aureus; Substrate Specificity

1994
Comparative analysis of percutaneous absorption enhancement by d-limonene and oleic acid based on a skin diffusion model.
    Pharmaceutical research, 1994, Volume: 11, Issue:3

    Topics: Animals; Cyclohexenes; Diffusion; Guinea Pigs; In Vitro Techniques; Limonene; Male; Mannitol; Mercaptopurine; Models, Biological; Oleic Acid; Oleic Acids; Parabens; Skin Absorption; Terpenes

1994
Production, nutritional profiles and storability of 'aadun' and 'kokoro': two corn products.
    Plant foods for human nutrition (Dordrecht, Netherlands), 1994, Volume: 45, Issue:2

    Topics: Food Handling; Food Preservation; Nigeria; Nutritive Value; Parabens; Zea mays

1994
In vivo and in vitro analysis of skin penetration enhancement based on a two-layer diffusion model with polar and nonpolar routes in the stratum corneum.
    Pharmaceutical research, 1994, Volume: 11, Issue:2

    Topics: Acyclovir; Animals; Azepines; Diffusion; Epidermis; In Vitro Techniques; Mannitol; Mathematics; Parabens; Rats; Rats, Wistar; Skin Absorption; Tissue Distribution

1994
Effects of the structures of polyoxyethylene alkyl ethers on uptake of butyl p-hydroxybenzoate by Escherichia coli and its antibacterial activity.
    Chemical & pharmaceutical bulletin, 1996, Volume: 44, Issue:12

    Topics: Escherichia coli; Kinetics; Microbial Sensitivity Tests; Parabens; Polidocanol; Polyethylene Glycols

1996
Effects of skin metabolism on percutaneous penetration of lipophilic drugs.
    Journal of pharmaceutical sciences, 1997, Volume: 86, Issue:6

    Topics: Animals; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Esterases; Male; Parabens; Rats; Rats, Wistar; Skin; Skin Absorption

1997
Prolonged erythema after chemical peel.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 1998, Volume: 24, Issue:8

    Topics: Asian People; Chemexfoliation; Erythema; Humans; Hyperpigmentation; Indians, North American; Medical History Taking; Parabens; Photosensitizing Agents; Preservatives, Pharmaceutical; Risk Factors

1998
Some alkyl hydroxy benzoate preservatives (parabens) are estrogenic.
    Toxicology and applied pharmacology, 1998, Volume: 153, Issue:1

    Topics: Animals; Binding, Competitive; Female; Food Preservatives; Organ Size; Parabens; Rats; Receptors, Estrogen; Tamoxifen; Uterus; Yeasts

1998
Theoretical analysis of the effect of cutaneous metabolism on skin permeation of parabens based on a two-layer skin diffusion/metabolism model.
    Biological & pharmaceutical bulletin, 1999, Volume: 22, Issue:3

    Topics: Animals; Diffusion; Male; Models, Biological; Parabens; Permeability; Rats; Rats, Wistar; Skin

1999
A centrifuge technique for the evaluation of the extent of water movement in wet powder masses.
    International journal of pharmaceutics, 1999, Oct-15, Volume: 188, Issue:1

    Topics: Cellulose; Centrifugation; Chemistry, Pharmaceutical; Parabens; Powders; Propyl Gallate; Water

1999
Membrane locus and pH sensitivity of paraben inhibition of alkali production by oral streptococci.
    Oral microbiology and immunology, 1999, Volume: 14, Issue:4

    Topics: Arginine; Biofilms; Biological Transport; Cell Membrane; Cell Membrane Permeability; Cytoplasm; Enzyme Inhibitors; Food Preservatives; Glycolysis; Hydrogen-Ion Concentration; Hydrolases; Parabens; Phosphotransferases (Carboxyl Group Acceptor); Streptococcus; Urea; Urease

1999
Physical properties of parabens and their mixtures: solubility in water, thermal behavior, and crystal structures.
    Journal of pharmaceutical sciences, 1999, Volume: 88, Issue:11

    Topics: Calorimetry, Differential Scanning; Chemical Phenomena; Chemistry, Physical; Crystallization; Crystallography, X-Ray; Hot Temperature; Parabens; Preservatives, Pharmaceutical; Solubility; Water

1999
A novel percolation method for determining solubilities of pharmaceutical agents in semisolid vehicles.
    Pharmaceutical development and technology, 1999, Volume: 4, Issue:4

    Topics: Anti-Inflammatory Agents; Chemistry, Pharmaceutical; Crystallization; Hydrocortisone; Ointment Bases; Parabens; Petrolatum; Pharmaceutical Preparations; Pharmaceutical Vehicles; Solubility

1999
The preservatives ethyl-, propyl- and butylparaben are oestrogenic in an in vivo fish assay.
    Pharmacology & toxicology, 2000, Volume: 86, Issue:3

    Topics: Animals; Biological Assay; Enzyme-Linked Immunosorbent Assay; Estrogens, Non-Steroidal; Female; Food Preservatives; Oncorhynchus mykiss; Parabens; Vitellogenins

2000
Decreased sperm number and motile activity on the F1 offspring maternally exposed to butyl p-hydroxybenzoic acid (butyl paraben).
    The Journal of veterinary medical science, 2002, Volume: 64, Issue:3

    Topics: Animals; Animals, Newborn; Body Weight; Female; Food Preservatives; Genitalia, Female; Genitalia, Male; Lactation; Male; Maternal Exposure; Organ Size; Parabens; Pregnancy; Prenatal Exposure Delayed Effects; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Sperm Count; Sperm Motility; Spermatogenesis

2002
Effects of butylparaben on the male reproductive system in rats.
    Toxicology and industrial health, 2001, Volume: 17, Issue:1

    Topics: Animals; Body Weight; Dietary Supplements; Genitalia, Male; Male; Organ Size; Parabens; Rats; Rats, Wistar; Sperm Count; Testis; Testosterone

2001
Effects of butyl paraben on the male reproductive system in mice.
    Archives of toxicology, 2002, Volume: 76, Issue:7

    Topics: Analysis of Variance; Animals; Body Weight; Food Preservatives; Gonadal Steroid Hormones; Male; Mice; Mice, Inbred ICR; Organ Size; Parabens; Spermatogenesis; Testis; Testosterone

2002
Benzoate X receptors alpha and beta are pharmacologically distinct and do not function as xenobiotic receptors.
    The Journal of biological chemistry, 2002, Nov-15, Volume: 277, Issue:46

    Topics: Animals; Benzoates; Benzocaine; Chlorpyrifos; COS Cells; DNA, Complementary; Dose-Response Relationship, Drug; Female; Intestinal Mucosa; Ligands; Liver; Male; Parabens; Protein Binding; Protein Structure, Tertiary; Receptors, Cytoplasmic and Nuclear; RNA; Tissue Distribution; Transfection; Trifluralin; Two-Hybrid System Techniques; Xenobiotics; Xenopus; Xenopus Proteins

2002
Additive estrogenic activities of the binary mixtures of four estrogenic chemicals in recombinant yeast expressing human estrogen receptor.
    Journal of veterinary science, 2002, Volume: 3, Issue:1

    Topics: Benzhydryl Compounds; Cloning, Molecular; Estradiol; Estrogens; Estrogens, Non-Steroidal; Humans; Kinetics; Parabens; Phenols; Receptors, Estrogen; Recombinant Proteins; Saccharomyces cerevisiae

2002
Determination of cisapride, its oxidation product, propyl and butyl parabens in pharmaceutical dosage form by reversed-phase liquid chromatography.
    Journal of pharmaceutical and biomedical analysis, 2003, Dec-04, Volume: 33, Issue:5

    Topics: Chromatography, High Pressure Liquid; Cisapride; Dosage Forms; Oxidation-Reduction; Parabens; Pharmaceutical Preparations

2003
Effect of heat on the percutaneous absorption and skin retention of three model penetrants.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2004, Volume: 21, Issue:2-3

    Topics: Adjuvants, Pharmaceutic; Administration, Cutaneous; Adult; Caffeine; Diffusion; Epidermis; Female; Heating; Humans; In Vitro Techniques; Membranes, Artificial; Models, Biological; Parabens; Permeability; Skin Absorption; Solubility; Thermodynamics

2004
Developmental toxicity evaluation of butylparaben in Sprague-Dawley rats.
    Birth defects research. Part B, Developmental and reproductive toxicology, 2004, Volume: 71, Issue:4

    Topics: Abnormalities, Drug-Induced; Animals; Drug Evaluation, Preclinical; Female; Fetal Development; Fetus; Parabens; Pregnancy; Rats; Rats, Sprague-Dawley

2004
Comment on developmental toxicity evaluation of butylparaben in Sprague-Dawley rats.
    Birth defects research. Part B, Developmental and reproductive toxicology, 2005, Volume: 74, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Female; Fetal Development; Fetus; Parabens; Pregnancy; Rats; Rats, Sprague-Dawley

2005
Estrogenicity of butylparaben in rainbow trout Oncorhynchus mykiss exposed via food and water.
    Aquatic toxicology (Amsterdam, Netherlands), 2005, May-15, Volume: 72, Issue:4

    Topics: Administration, Oral; Analysis of Variance; Animals; Chromatography, Liquid; Denmark; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Liver; Mass Spectrometry; Muscle, Skeletal; Oncorhynchus mykiss; Parabens; Time Factors; Vitellogenesis; Vitellogenins

2005
Morphometric analysis of mice uteri treated with the preservatives methyl, ethyl, propyl, and butylparaben.
    Toxicology and industrial health, 2004, Volume: 20, Issue:6-10

    Topics: Animals; Dose-Response Relationship, Drug; Estrogens; Female; Food Preservatives; Mice; Ovariectomy; Parabens; Preservatives, Pharmaceutical; Uterus

2004
The effect of unsaturated fatty acids in benzyl alcohol on the percutaneous permeation of three model penetrants.
    International journal of pharmaceutics, 2005, Sep-14, Volume: 301, Issue:1-2

    Topics: Algorithms; Benzyl Alcohol; Caffeine; Central Nervous System Stimulants; Chemical Phenomena; Chemistry, Physical; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Diffusion Chambers, Culture; Fatty Acids, Unsaturated; Female; Humans; In Vitro Techniques; Middle Aged; Parabens; Permeability; Pharmaceutic Aids; Skin Absorption; Solutions

2005
Effector-repressor interactions, binding of a single effector molecule to the operator-bound TtgR homodimer mediates derepression.
    The Journal of biological chemistry, 2006, Mar-17, Volume: 281, Issue:11

    Topics: Anti-Infective Agents; Bacterial Proteins; beta-Galactosidase; Calorimetry; Chloramphenicol; Dimerization; Drug Resistance, Multiple; Entropy; Evolution, Molecular; Flavonoids; Gene Expression Regulation, Bacterial; Hot Temperature; Kinetics; Models, Chemical; Models, Molecular; Naphthols; Operator Regions, Genetic; Parabens; Phloretin; Plasmids; Polymerase Chain Reaction; Protein Binding; Protein Conformation; Pseudomonas putida; Quercetin; Repressor Proteins; Solvents; Structure-Activity Relationship; Temperature; Thermodynamics; Time Factors; Transcription, Genetic

2006
Simultaneous analysis of antioxidants and preservatives in cosmetics by supercritical fluid extraction combined with liquid chromatography-mass spectrometry.
    Journal of chromatography. A, 2006, Jul-07, Volume: 1120, Issue:1-2

    Topics: Antioxidants; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Chromatography, High Pressure Liquid; Chromatography, Supercritical Fluid; Cosmetics; Molecular Structure; Parabens; Preservatives, Pharmaceutical; Pressure; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Temperature

2006
Variability in human skin permeability in vitro: comparing penetrants with different physicochemical properties.
    Journal of pharmaceutical sciences, 2007, Volume: 96, Issue:4

    Topics: Caffeine; Humans; Parabens; Permeability; Skin Absorption; Solubility

2007
Investigating protein haptenation mechanisms of skin sensitisers using human serum albumin as a model protein.
    Toxicology in vitro : an international journal published in association with BIBRA, 2007, Volume: 21, Issue:4

    Topics: Acetylation; Benzaldehydes; Chromatography, High Pressure Liquid; Dermatitis, Contact; Dinitrochlorobenzene; Haptens; Hydrolysis; Irritants; Mass Spectrometry; Models, Molecular; Molecular Weight; Nitrobenzenes; Parabens; Peptide Mapping; Salicylates; Serum Albumin; Skin; Sodium Dodecyl Sulfate; Trypsin

2007
Influence of crystal structure on the tableting properties of n-alkyl 4-hydroxybenzoate esters (parabens).
    Journal of pharmaceutical sciences, 2007, Volume: 96, Issue:12

    Topics: Chemistry, Pharmaceutical; Crystallization; Drug Compounding; Hardness; Hardness Tests; Models, Chemical; Molecular Structure; Parabens; Porosity; Powders; Pressure; Structure-Activity Relationship; Tablets; Technology, Pharmaceutical; Tensile Strength

2007
Effect of abrasion induced by a rotating brush on the skin permeation of solutes with varying physicochemical properties.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2008, Volume: 68, Issue:3

    Topics: Acyclovir; Angiotensin II; Caffeine; Humans; Parabens; Permeability; Rotation; Skin; Technology, Pharmaceutical

2008
[Enhancement of di-n-butyl phthalate on the estrogenic activities of esters of p-hydroxybenzoic acid].
    Wei sheng yan jiu = Journal of hygiene research, 2007, Volume: 36, Issue:3

    Topics: Animals; Animals, Newborn; Dibutyl Phthalate; Drug Synergism; Endocrine Disruptors; Female; Parabens; Rats; Rats, Wistar; Uterus

2007
Assessment of principal parabens used in cosmetics after their passage through human epidermis-dermis layers (ex-vivo study).
    Experimental dermatology, 2007, Volume: 16, Issue:10

    Topics: Adult; Cosmetics; Dermis; Epidermis; Female; Humans; In Vitro Techniques; Parabens; Permeability; Skin; Skin Absorption; Time Factors

2007
Hydrolysis of a series of parabens by skin microsomes and cytosol from human and minipigs and in whole skin in short-term culture.
    Toxicology and applied pharmacology, 2007, Dec-01, Volume: 225, Issue:2

    Topics: Adult; Animals; Carboxylic Ester Hydrolases; Cytosol; Enzyme Inhibitors; Female; Humans; Hydrolysis; Male; Microsomes; Models, Animal; Parabens; Preservatives, Pharmaceutical; Skin; Skin Absorption; Species Specificity; Swine; Swine, Miniature

2007
Preparation and characterization of inclusion complexes of a cationic beta-cyclodextrin polymer with butylparaben or triclosan.
    International journal of pharmaceutics, 2008, Jun-05, Volume: 357, Issue:1-2

    Topics: Anti-Infective Agents, Local; beta-Cyclodextrins; Cations; Escherichia coli; Excipients; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Microscopy, Atomic Force; Parabens; Solubility; Spectroscopy, Fourier Transform Infrared; Triclosan; Wood

2008
Preliminary ecological risk assessment of butylparaben and benzylparaben -1. Removal efficiency in wastewater treatment, acute/chronic toxicity for aquatic organisms, and effects on medaka gene expression.
    Environmental sciences : an international journal of environmental physiology and toxicology, 2007, Volume: 14 Suppl

    Topics: Animals; Ecology; Gene Expression; Industrial Waste; No-Observed-Adverse-Effect Level; Oligonucleotide Array Sequence Analysis; Oryzias; Parabens; Risk Assessment; Sewage; Waste Management; Water Pollutants, Chemical

2007
Preliminary ecological risk assessment of butylparaben and benzylparaben -2. Fate and partitioning in aquatic environments.
    Environmental sciences : an international journal of environmental physiology and toxicology, 2007, Volume: 14 Suppl

    Topics: Biodegradation, Environmental; Ecology; Parabens; Photolysis; Risk Assessment; Rivers; Sunlight; Water Pollutants, Chemical

2007
Lack of effect of butylparaben and methylparaben on the reproductive system in male rats.
    Birth defects research. Part B, Developmental and reproductive toxicology, 2008, Volume: 83, Issue:2

    Topics: Animals; Body Weight; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Genitalia, Male; Male; Organ Size; Parabens; Preservatives, Pharmaceutical; Rats; Rats, Sprague-Dawley; Rats, Wistar; Skin

2008
Do parabens have the ability to interfere with steroidogenesis?
    Toxicological sciences : an official journal of the Society of Toxicology, 2008, Volume: 106, Issue:1

    Topics: Adrenal Glands; Animals; Cell Line; Cell Proliferation; Dose-Response Relationship, Drug; Endocrine Disruptors; Female; Gestational Age; Gonadal Steroid Hormones; Male; Ovary; Parabens; Phosphoproteins; Pituitary Gland; Pregnancy; Prenatal Exposure Delayed Effects; Progesterone; Rats; Rats, Wistar; Receptors, Estradiol; Receptors, GABA-A; Receptors, Thyroid Hormone; RNA, Messenger; Testis; Testosterone

2008
Short-term iontophoretic and post-iontophoretic transport of model penetrants across excised human epidermis.
    International journal of pharmaceutics, 2009, Feb-09, Volume: 367, Issue:1-2

    Topics: Administration, Cutaneous; Caffeine; Chromatography, High Pressure Liquid; Electrochemistry; Electrodes; Epidermis; Humans; In Vitro Techniques; Iontophoresis; Microscopy, Electron, Scanning; Models, Biological; Parabens; Skin Absorption; Solvents; Surface Properties; Time Factors

2009
The aqueous photosensitized degradation of butylparaben.
    Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 2009, Volume: 8, Issue:4

    Topics: Estrogens; Humans; Models, Molecular; Parabens; Photochemistry; Preservatives, Pharmaceutical; Rose Bengal; Singlet Oxygen; Skin; Spectrophotometry; Spectrophotometry, Ultraviolet; Water

2009
[Butyl-p-hydroxybenzoate stimulates cystic fibrosis transmembrane conductance regulator Cl- transport].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2009, Volume: 44, Issue:1

    Topics: Animals; Cell Line; Cystic Fibrosis Transmembrane Conductance Regulator; Dose-Response Relationship, Drug; Epithelial Cells; Green Fluorescent Proteins; Ion Channel Gating; Mutation; Parabens; Rats; Rats, Inbred F344; Thyroid Gland

2009
Estrogenicity of parabens revisited: impact of parabens on early pregnancy and an uterotrophic assay in mice.
    Reproductive toxicology (Elmsford, N.Y.), 2009, Volume: 28, Issue:1

    Topics: Animals; Animals, Newborn; Birth Weight; Dose-Response Relationship, Drug; Embryo Implantation; Endocrine Disruptors; Estradiol; Estrogens; Female; Food Preservatives; Gestational Age; Injections, Subcutaneous; Litter Size; Mice; Organ Size; Ovariectomy; Parabens; Pregnancy; Preservatives, Pharmaceutical; Reproduction; Risk Assessment; Uterus

2009
Relating solubility data of parabens in liquid PEG 400 to the behaviour of PEG 4000-parabens solid dispersions.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2009, Volume: 73, Issue:2

    Topics: Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Dosage Forms; Drug Carriers; Drug Compounding; Molecular Conformation; Parabens; Polyethylene Glycols; Solubility; Solutions; Transition Temperature; X-Ray Diffraction

2009
Urinary concentrations of four parabens in the U.S. population: NHANES 2005-2006.
    Environmental health perspectives, 2010, Volume: 118, Issue:5

    Topics: Adolescent; Adult; Aged; Child; Chromatography, High Pressure Liquid; Environmental Exposure; Environmental Health; Environmental Monitoring; Female; Food Preservatives; Humans; Male; Middle Aged; Parabens; Preservatives, Pharmaceutical; Solid Phase Extraction; Tandem Mass Spectrometry; United States; Young Adult

2010
Potential estrogenic effect(s) of parabens at the prepubertal stage of a postnatal female rat model.
    Reproductive toxicology (Elmsford, N.Y.), 2010, Volume: 29, Issue:3

    Topics: Adrenal Glands; Animals; Endocrine System Diseases; Estradiol; Estrous Cycle; Ethinyl Estradiol; Female; Liver; Organ Size; Parabens; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Reproduction; Risk Factors; Thyroid Gland; Thyroid Hormones; Thyroxine; Uterus; Vagina

2010
Synthetic approaches to parabens molecularly imprinted polymers and their applications to the solid-phase extraction of river water samples.
    Analytica chimica acta, 2010, Sep-10, Volume: 677, Issue:1

    Topics: Molecular Imprinting; Parabens; Polymers; Rivers; Solid Phase Extraction

2010
Simultaneous determination of electroactive and non-electroactive food preservatives by novel capillary electrophoresis with amperometric detection.
    Analytica chimica acta, 2010, Sep-23, Volume: 678, Issue:1

    Topics: Dopamine; Electrochemical Techniques; Electrodes; Electrophoresis, Capillary; Food Preservatives; Hydrogen-Ion Concentration; Parabens; Reproducibility of Results; Sodium Lactate; Sorbic Acid

2010
The consequence of the chemical composition of HPMC in matrix tablets on the release behaviour of model drug substances having different solubility.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2011, Volume: 77, Issue:1

    Topics: Chemical Phenomena; Delayed-Action Preparations; Drug Compounding; Excipients; Gels; Hydrophobic and Hydrophilic Interactions; Hypromellose Derivatives; Kinetics; Methylcellulose; Parabens; Pharmaceutical Preparations; Reproducibility of Results; Solubility; Tablets; Transition Temperature; Viscosity

2011
Butyl paraben-induced changes in DNA methylation in rat epididymal spermatozoa.
    Andrologia, 2012, Volume: 44 Suppl 1

    Topics: Animals; DNA Methylation; Dose-Response Relationship, Drug; Epididymis; Male; Parabens; Random Amplified Polymorphic DNA Technique; Rats; Spermatozoa

2012
High performance liquid chromatography column packings with deliberately broadened particle size distribution: relation between column performance and packing structure.
    Journal of chromatography. A, 2011, Sep-23, Volume: 1218, Issue:38

    Topics: Chromatography, High Pressure Liquid; Kinetics; Parabens; Particle Size; Permeability; Porosity; Silicon Dioxide

2011
Effects of parabens on apoptosis induced by serum-free medium.
    Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes, 2012, Volume: 47, Issue:3

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; bcl-Associated Death Protein; Biomarkers; Caspase 3; Culture Media, Serum-Free; Enzyme-Linked Immunosorbent Assay; Food Preservatives; In Situ Nick-End Labeling; Parabens; PC12 Cells; Preservatives, Pharmaceutical; Proto-Oncogene Proteins c-bcl-2; Rats; Reverse Transcriptase Polymerase Chain Reaction

2012
Predictors and variability of urinary paraben concentrations in men and women, including before and during pregnancy.
    Environmental health perspectives, 2012, Volume: 120, Issue:11

    Topics: Adult; Age Factors; Chromatography, High Pressure Liquid; Cohort Studies; Environmental Exposure; Environmental Monitoring; Female; Food Preservatives; Humans; Linear Models; Male; Massachusetts; Middle Aged; Parabens; Pregnancy; Preservatives, Pharmaceutical; Prospective Studies; Sex Factors; Socioeconomic Factors; Tandem Mass Spectrometry; Young Adult

2012
Parabens enable suspension growth of MCF-10A immortalized, non-transformed human breast epithelial cells.
    Journal of applied toxicology : JAT, 2013, Volume: 33, Issue:5

    Topics: Breast; Cell Line; Cell Proliferation; Dose-Response Relationship, Drug; Epithelial Cells; Female; Food Preservatives; Humans; Parabens

2013
Protective role of metabolism by intestinal microflora in butyl paraben-induced toxicity in HepG2 cell cultures.
    Toxicology letters, 2012, Sep-03, Volume: 213, Issue:2

    Topics: Anthracenes; Apoptosis; bcl-2-Associated X Protein; Cell Survival; Feces; Female; Hep G2 Cells; Humans; In Situ Nick-End Labeling; Intestinal Mucosa; Intestines; Male; Parabens; Proto-Oncogene Proteins c-bcl-2; Real-Time Polymerase Chain Reaction; RNA, Messenger

2012
Metabolism and disposition of [14C]n-butyl-p-hydroxybenzoate in male and female Harlan Sprague Dawley rats following oral administration and dermal application.
    Xenobiotica; the fate of foreign compounds in biological systems, 2013, Volume: 43, Issue:2

    Topics: Administration, Cutaneous; Administration, Oral; Animals; Carbon Radioisotopes; Female; Hepatocytes; Humans; Injections, Intravenous; Male; Parabens; Rats; Rats, Sprague-Dawley; Xenobiotics

2013
p-Hydroxybenzoate esters metabolism in MCF7 breast cancer cells.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2012, Volume: 50, Issue:11

    Topics: Breast Neoplasms; Cell Line, Tumor; Chromatography, High Pressure Liquid; Female; Food Preservatives; Glucuronosyltransferase; Humans; Hydrolysis; Parabens; Sulfotransferases

2012
Here today, here tomorrow? Urinary concentrations of parabens over time.
    Environmental health perspectives, 2012, Volume: 120, Issue:11

    Topics: Environmental Exposure; Female; Food Preservatives; Humans; Male; Parabens; Pregnancy; Preservatives, Pharmaceutical

2012
Solubilization of parabens in aqueous Pluronic solutions: investigating the micellar growth and interaction as a function of paraben composition.
    The journal of physical chemistry. B, 2012, Dec-27, Volume: 116, Issue:51

    Topics: Hydrophobic and Hydrophilic Interactions; Micelles; Parabens; Poloxamer; Polyethylene Glycols; Propylene Glycols; Solubility; Transition Temperature; Water

2012
Comparative study on transcriptional activity of 17 parabens mediated by estrogen receptor α and β and androgen receptor.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 57

    Topics: Androgen Receptor Antagonists; Animals; CHO Cells; Cricetulus; Dose-Response Relationship, Drug; Estrogen Receptor alpha; Estrogen Receptor beta; Humans; Hydrolysis; Isomerism; Microsomes, Liver; Parabens; Rats; Receptors, Androgen; Structure-Activity Relationship

2013
Solid lipid nanoparticles as effective reservoir systems for long-term preservation of multidose formulations.
    AAPS PharmSciTech, 2013, Volume: 14, Issue:2

    Topics: Candida albicans; Chemistry, Pharmaceutical; Delayed-Action Preparations; Diglycerides; Drug Carriers; Drug Contamination; Kinetics; Microbial Sensitivity Tests; Nanoparticles; Parabens; Particle Size; Plant Oils; Polyethylene Glycols; Preservatives, Pharmaceutical; Sodium Cholate; Solubility; Technology, Pharmaceutical; Water

2013
Photo-degradation of butyl parahydroxybenzoate by using TiO2-supported catalyst.
    Water science and technology : a journal of the International Association on Water Pollution Research, 2013, Volume: 67, Issue:10

    Topics: Catalysis; Kinetics; Oxidation-Reduction; Parabens; Photochemical Processes; Titanium

2013
Effects of single and repeated in vitro exposure of three forms of parabens, methyl-, butyl- and propylparabens on the proliferation and estradiol secretion in MCF-7 and MCF-10A cells.
    Pharmacological reports : PR, 2013, Volume: 65, Issue:2

    Topics: Aromatase; Blotting, Western; Breast Neoplasms; Cell Line; Cell Proliferation; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Estradiol; Female; Gene Expression Regulation; Humans; MCF-7 Cells; Parabens; Real-Time Polymerase Chain Reaction; Time Factors

2013
A new treatment by dispersive liquid-liquid microextraction for the determination of parabens in human serum samples.
    Analytical and bioanalytical chemistry, 2013, Volume: 405, Issue:23

    Topics: Chromatography, High Pressure Liquid; Glucuronidase; Humans; Hydrogen-Ion Concentration; Limit of Detection; Liquid Phase Microextraction; Parabens; Preservatives, Pharmaceutical; Serum; Solvents; Sulfatases

2013
Combined prenatal and postnatal butyl paraben exposure produces autism-like symptoms in offspring: comparison with valproic acid autistic model.
    Pharmacology, biochemistry, and behavior, 2013, Volume: 111

    Topics: Animals; Autistic Disorder; Female; Male; Maternal Exposure; Models, Theoretical; Parabens; Pregnancy; Rats; Valproic Acid

2013
Ruthenium nanoparticles supported on CeO2 for catalytic permanganate oxidation of butylparaben.
    Environmental science & technology, 2013, Nov-19, Volume: 47, Issue:22

    Topics: Catalysis; Cerium; Environment; Hydrogen-Ion Concentration; Kinetics; Manganese Compounds; Minerals; Nanoparticles; Oxidation-Reduction; Oxides; Parabens; Ruthenium; X-Ray Absorption Spectroscopy

2013
Single administration of butylparaben induces spermatogenic cell apoptosis in prepubertal rats.
    Acta histochemica, 2014, Volume: 116, Issue:3

    Topics: Animals; Apoptosis; Endocrine Disruptors; Estradiol Congeners; Male; Parabens; Rats, Sprague-Dawley; Spermatocytes; Spermatogonia; Testis

2014
Late-life effects on rat reproductive system after developmental exposure to mixtures of endocrine disrupters.
    Reproduction (Cambridge, England), 2014, Volume: 147, Issue:4

    Topics: Acetaminophen; Aging; Animals; Benzhydryl Compounds; Camphor; Cinnamates; Endocrine Disruptors; Female; Genitalia; Male; Parabens; Phenols; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Reproduction; Sexual Maturation

2014
Disruption of Sertoli cell vimentin filaments in prepubertal rats: an acute effect of butylparaben in vivo and in vitro.
    Acta histochemica, 2014, Volume: 116, Issue:5

    Topics: Animals; Food Preservatives; Immunohistochemistry; Male; Parabens; Rats; Rats, Sprague-Dawley; Sertoli Cells; Sexual Maturation; Testis; Vimentin

2014
Differential effect of methyl-, butyl- and propylparaben and 17β-estradiol on selected cell cycle and apoptosis gene and protein expression in MCF-7 breast cancer cells and MCF-10A non-malignant cells.
    Journal of applied toxicology : JAT, 2014, Volume: 34, Issue:9

    Topics: Apoptosis; Apoptosis Regulatory Proteins; bcl-X Protein; Caspase 9; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Epithelial Cells; Estradiol; Female; Humans; MCF-7 Cells; Parabens; Real-Time Polymerase Chain Reaction; RNA, Messenger; Up-Regulation

2014
Effects of n-butylparaben on steroidogenesis and spermatogenesis through changed E₂ levels in male rat offspring.
    Environmental toxicology and pharmacology, 2014, Volume: 37, Issue:2

    Topics: Animals; Estradiol; Female; Follicle Stimulating Hormone; Luteinizing Hormone; Male; Maternal-Fetal Exchange; Organ Size; Parabens; Pregnancy; Prenatal Exposure Delayed Effects; Rats, Wistar; Sperm Count; Spermatogenesis; Testis; Testosterone

2014
Exposure to parabens at the concentration of maximal proliferative response increases migratory and invasive activity of human breast cancer cells in vitro.
    Journal of applied toxicology : JAT, 2014, Volume: 34, Issue:9

    Topics: beta Catenin; Cadherins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dose-Response Relationship, Drug; Down-Regulation; Epithelial-Mesenchymal Transition; Estradiol; Estrogens; Female; Humans; MCF-7 Cells; Neoplasm Invasiveness; Parabens; Preservatives, Pharmaceutical

2014
Photosonochemical degradation of butyl-paraben: optimization, toxicity and kinetic studies.
    The Science of the total environment, 2014, Aug-15, Volume: 490

    Topics: Models, Chemical; Oxidation-Reduction; Parabens; Photochemical Processes; Sonication; Ultraviolet Rays; Water Pollutants, Chemical

2014
Actions of methyl-, propyl- and butylparaben on estrogen receptor-α and -β and the progesterone receptor in MCF-7 cancer cells and non-cancerous MCF-10A cells.
    Toxicology letters, 2014, Nov-04, Volume: 230, Issue:3

    Topics: Cell Line; Epithelial Cells; Estradiol; Estrogen Receptor alpha; Humans; MCF-7 Cells; Parabens; Receptors, Estrogen; Receptors, Progesterone; RNA, Messenger

2014
Associations between urinary phenol and paraben concentrations and markers of oxidative stress and inflammation among pregnant women in Puerto Rico.
    International journal of hygiene and environmental health, 2015, Volume: 218, Issue:2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Adolescent; Adult; Benzhydryl Compounds; Benzophenones; Biomarkers; Body Mass Index; C-Reactive Protein; Chlorophenols; Deoxyguanosine; Educational Status; Female; Humans; Inflammation; Inflammation Mediators; Interleukin-10; Interleukin-1beta; Interleukin-6; Isoprostanes; Maternal Exposure; Oxidative Stress; Parabens; Phenol; Phenols; Pregnancy; Pregnancy Outcome; Puerto Rico; Triclosan; Tumor Necrosis Factor-alpha; Young Adult

2015
Glucocorticoid-like activity of propylparaben, butylparaben, diethylhexyl phthalate and tetramethrin mixtures studied in the MDA-kb2 cell line.
    Toxicology letters, 2015, Jan-22, Volume: 232, Issue:2

    Topics: Animals; Cell Survival; Diethylhexyl Phthalate; Dogs; Glucocorticoids; Insecticides; Madin Darby Canine Kidney Cells; Parabens; Plasticizers; Pyrethrins; Receptors, Glucocorticoid

2015
Interplay between pro-inflammatory cytokines and brain oxidative stress biomarkers: evidence of parallels between butyl paraben intoxication and the valproic acid brain physiopathology in autism rat model.
    Cytokine, 2015, Volume: 71, Issue:2

    Topics: Adenosine Monophosphate; Adenosine Triphosphate; Animals; Autistic Disorder; Biomarkers; Brain; Brain Diseases; Chromatography, High Pressure Liquid; Female; Glutathione; Glutathione Disulfide; Inflammation Mediators; Interleukin-1beta; Interleukin-6; Male; Mitochondria; Oxidative Stress; Parabens; Pregnancy; Rats, Wistar; Tumor Necrosis Factor-alpha; Tyrosine; Valproic Acid

2015
A case study on quantitative in vitro to in vivo extrapolation for environmental esters: Methyl-, propyl- and butylparaben.
    Toxicology, 2015, Jun-05, Volume: 332

    Topics: Adult; Animals; Biotransformation; Cells, Cultured; Endocrine Disruptors; Environmental Pollutants; Female; Genes, Reporter; Humans; Hydrolysis; Linear Models; Male; Models, Biological; Nutrition Surveys; Parabens; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Estrogen; Risk Assessment; Risk Factors; Solubility; Tissue Distribution; Toxicity Tests

2015
The metal-organic framework HKUST-1 as efficient sorbent in a vortex-assisted dispersive micro solid-phase extraction of parabens from environmental waters, cosmetic creams, and human urine.
    Talanta, 2015, Jul-01, Volume: 139

    Topics: Chromatography, High Pressure Liquid; Cosmetics; Humans; Metal-Organic Frameworks; Metals; Organometallic Compounds; Parabens; Solid Phase Extraction; Urinalysis; Urine; Water Pollutants, Chemical

2015
Action of methyl-, propyl- and butylparaben on GPR30 gene and protein expression, cAMP levels and activation of ERK1/2 and PI3K/Akt signaling pathways in MCF-7 breast cancer cells and MCF-10A non-transformed breast epithelial cells.
    Toxicology letters, 2015, Oct-14, Volume: 238, Issue:2

    Topics: Apoptosis; Breast Neoplasms; Cyclic AMP; Epithelial Cells; Estradiol; Female; Humans; Mammary Glands, Human; MCF-7 Cells; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Parabens; Phosphatidylinositol 3-Kinase; Proto-Oncogene Proteins c-akt; Receptors, Estrogen; Receptors, G-Protein-Coupled; Signal Transduction; Time Factors; Up-Regulation

2015
Temperature influencing permeation pattern of alfuzosin: an investigation using DoE.
    Medicina (Kaunas, Lithuania), 2015, Volume: 51, Issue:4

    Topics: Absorption, Physicochemical; Administration, Cutaneous; Adrenergic alpha-1 Receptor Antagonists; Cadaver; Caffeine; Cellulose; Epidermis; Hot Temperature; Humans; Membranes, Artificial; Parabens; Permeability; Pharmaceutical Vehicles; Quinazolines; Solubility; Urological Agents

2015
Polycyclodextrin and Carbon Nanotubes as Composite for Tyrosinase Immobilization and Its Superior Electrocatalytic Activity Towards Butylparaben an Endocrine Disruptor.
    Journal of nanoscience and nanotechnology, 2015, Volume: 15, Issue:5

    Topics: Biosensing Techniques; Cellulose; Cosmetics; Cyclodextrins; Electrochemical Techniques; Endocrine Disruptors; Enzyme Stability; Enzymes, Immobilized; Limit of Detection; Monophenol Monooxygenase; Nanotubes, Carbon; Parabens; Reproducibility of Results

2015
Metabolism and elimination of methyl, iso- and n-butyl paraben in human urine after single oral dosage.
    Archives of toxicology, 2016, Volume: 90, Issue:11

    Topics: Adult; Biomarkers; Biotransformation; Deuterium; Endocrine Disruptors; Environmental Exposure; Environmental Monitoring; Food Preservatives; Germany; Hippurates; Humans; Hydroxylation; Oxidation-Reduction; Parabens; Preservatives, Pharmaceutical; Renal Elimination; Stereoisomerism; Toxicokinetics

2016
Individual and combined in vitro (anti)androgenic effects of certain food additives and cosmetic preservatives.
    Toxicology in vitro : an international journal published in association with BIBRA, 2016, Volume: 32

    Topics: Androgen Antagonists; Androgens; Antioxidants; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Cell Line, Tumor; Cell Survival; Cosmetics; Dihydrotestosterone; Endocrine Disruptors; Food Additives; Genes, Reporter; Humans; Luciferases; Parabens; Preservatives, Pharmaceutical; Propyl Gallate; Receptors, Androgen

2016
Establishing the importance of oil-membrane interactions on the transmembrane diffusion of physicochemically diverse compounds.
    International journal of pharmaceutics, 2016, Jun-15, Volume: 506, Issue:1-2

    Topics: Caffeine; Chemistry, Pharmaceutical; Diffusion; Excipients; Membranes, Artificial; Oils; Parabens; Skin Absorption; Solubility

2016
UHPLC-MS/MS Determination, Pharmacokinetic, and Bioavailability Study of Taxifolin in Rat Plasma after Oral Administration of its Nanodispersion.
    Molecules (Basel, Switzerland), 2016, Apr-14, Volume: 21, Issue:4

    Topics: Administration, Intravenous; Administration, Oral; Animals; Biological Availability; Chromatography, High Pressure Liquid; Humans; Inflammation; Liquid-Liquid Extraction; Parabens; Quercetin; Rats; Tandem Mass Spectrometry

2016
Urinary levels of bisphenol A, benzophenones and parabens in Tunisian women: A pilot study.
    The Science of the total environment, 2016, 08-15, Volume: 562

    Topics: Adult; Benzhydryl Compounds; Benzophenones; Endocrine Disruptors; Environmental Exposure; Environmental Pollutants; Female; Humans; Parabens; Phenols; Pilot Projects

2016
Multiple Endocrine Disrupting Effects in Rats Perinatally Exposed to Butylparaben.
    Toxicological sciences : an official journal of the Society of Toxicology, 2016, Volume: 152, Issue:1

    Topics: Animals; Animals, Newborn; Aromatase; Dose-Response Relationship, Drug; Endocrine Disruptors; Female; Gene Expression Regulation, Enzymologic; Gestational Age; Male; Mammary Glands, Animal; Maternal Exposure; Ovary; Parabens; Pregnancy; Prenatal Exposure Delayed Effects; Prostate; Rats, Wistar; Sperm Count; Steroidogenic Factor 1; Testis

2016
Effects of in vitro exposure to butylparaben and di-(2 ethylhexyl) phthalate, alone or in combination, on ovarian function.
    Journal of applied toxicology : JAT, 2016, Volume: 36, Issue:9

    Topics: Animals; Cells, Cultured; Diethylhexyl Phthalate; Endocrine Disruptors; Estradiol; Female; Granulosa Cells; Humans; Mice; Mice, Inbred C57BL; Ovarian Follicle; Parabens; Progesterone

2016
In vitro skin absorption tests of three types of parabens using a Franz diffusion cell.
    Journal of exposure science & environmental epidemiology, 2017, Volume: 27, Issue:3

    Topics: Analysis of Variance; Animals; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Male; Mice; Mice, Hairless; Parabens; Permeability; Preservatives, Pharmaceutical; Skin; Skin Absorption

2017
Maternal exposure to butyl paraben impairs testicular structure and sperm quality on male rats.
    Environmental toxicology, 2017, Volume: 32, Issue:4

    Topics: Animals; Estrogen Receptor alpha; Female; Follicle Stimulating Hormone; Gestational Age; Injections, Subcutaneous; Leydig Cells; Luteinizing Hormone; Male; Maternal Exposure; Parabens; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Receptors, Androgen; Sperm Motility; Spermatogenesis; Spermatozoa; Testis; Testosterone

2017
Differential effects on adiposity and serum marker of bone formation by post-weaning exposure to methylparaben and butylparaben.
    Environmental science and pollution research international, 2016, Volume: 23, Issue:21

    Topics: Adiposity; Animals; Biomarkers; Body Weight; Bone Remodeling; Collagen Type I; Feeding Behavior; Female; Male; Mice; Mice, Inbred C57BL; Osteogenesis; Parabens; Peptide Fragments; Peptides; Preservatives, Pharmaceutical; Procollagen; Random Allocation; Weaning

2016
Chlorination of parabens: reaction kinetics and transformation product identification.
    Environmental science and pollution research international, 2016, Volume: 23, Issue:22

    Topics: Ammonium Compounds; Chlorine; Gas Chromatography-Mass Spectrometry; Halogenation; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; Parabens; Temperature; Water Pollutants, Chemical; Water Quality

2016
Efficient degradation of butylparaben by gamma radiolysis.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2017, Volume: 122

    Topics: Dose-Response Relationship, Radiation; Environmental Restoration and Remediation; Gamma Rays; Germination; Oxidants; Ozone; Parabens; Plants; Water Pollutants, Chemical

2017
Parabens Accelerate Ovarian Dysfunction in a 4-Vinylcyclohexene Diepoxide-Induced Ovarian Failure Model.
    International journal of environmental research and public health, 2017, 02-08, Volume: 14, Issue:2

    Topics: Animals; Cyclohexenes; Estrus; Female; Ovarian Follicle; Parabens; Preservatives, Pharmaceutical; Rats; Rats, Sprague-Dawley; RNA, Messenger; Vinyl Compounds

2017
Effects on the reproductive system of young male rats of subcutaneous exposure to n-butylparaben.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2017, Volume: 106, Issue:Pt A

    Topics: Animals; Male; Organ Size; Parabens; Rats; Rats, Sprague-Dawley; Reproduction; Sperm Motility; Spermatogenesis; Spermatozoa

2017
Methylparaben and butylparaben alter multipotent mesenchymal stem cell fates towards adipocyte lineage.
    Toxicology and applied pharmacology, 2017, 08-15, Volume: 329

    Topics: Adipocytes; Adipogenesis; Animals; Cell Line; Cell Lineage; Chondrogenesis; Mesenchymal Stem Cells; Mice, Inbred C3H; Osteogenesis; Parabens; Phenotype; PPAR gamma; Receptors, Glucocorticoid; Risk Assessment; RNA Interference; Signal Transduction; Time Factors; Transfection

2017
Detection of bisphenol A, cumylphenol and parabens in surface waters of Greater Poland Voivodeship.
    Journal of environmental management, 2017, Dec-15, Volume: 204, Issue:Pt 1

    Topics: Benzhydryl Compounds; Endocrine Disruptors; Parabens; Phenols; Poland; Rivers

2017
Genotoxic effects in transformed and non-transformed human breast cell lines after exposure to silver nanoparticles in combination with aluminium chloride, butylparaben or di-n-butylphthalate.
    Toxicology in vitro : an international journal published in association with BIBRA, 2017, Volume: 45, Issue:Pt 1

    Topics: Aluminum Chloride; Aluminum Compounds; Breast; Cell Line, Transformed; Cell Line, Tumor; Chlorides; Dibutyl Phthalate; Female; Humans; Metal Nanoparticles; Mutagenicity Tests; Parabens; Silver

2017
Comparative toxic effects of butylparaben sodium, sodium diacetate and potassium sorbate to Dunaliella tertiolecta and HL7702 cells.
    Food & function, 2017, Dec-13, Volume: 8, Issue:12

    Topics: Acetates; Carotenoids; Cell Line; Chlorophyll; Chlorophyta; Food Preservatives; Humans; Microalgae; Parabens; Sorbic Acid

2017
Bonding of Butylparaben, Bis(2-ethylhexyl)-phthalate, and Perfluorooctanesulfonic Acid to DNA: Comparison with Benzo[a]pyrene Shows Low Probability for Strong Noncovalent DNA Intercalation.
    Chemical research in toxicology, 2018, 01-16, Volume: 31, Issue:1

    Topics: Alkanesulfonic Acids; Benzo(a)pyrene; Diethylhexyl Phthalate; DNA; Fluorocarbons; Intercalating Agents; Molecular Dynamics Simulation; Parabens; Quantum Theory

2018
Butyl paraben promotes apoptosis in human trophoblast cells through increased oxidative stress-induced endoplasmic reticulum stress.
    Environmental toxicology, 2018, Volume: 33, Issue:4

    Topics: Anti-Infective Agents; Apoptosis; Cell Line; Cell Proliferation; Chromones; Endoplasmic Reticulum Stress; Glycogen Synthase Kinase 3 beta; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Morpholines; Oxidative Stress; Parabens; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Signal Transduction; Trophoblasts

2018
Reproductive toxic impact of subchronic treatment with combined butylparaben and triclosan in weanling male rats.
    Journal of biochemical and molecular toxicology, 2018, Volume: 32, Issue:3

    Topics: Animals; DNA Damage; Gonadal Steroid Hormones; Male; Oxidative Stress; Parabens; Rats; Rats, Wistar; Testis; Triclosan

2018
Estrogenic and anti-estrogenic activity of butylparaben, butylated hydroxyanisole, butylated hydroxytoluene and propyl gallate and their binary mixtures on two estrogen responsive cell lines (T47D-Kbluc, MCF-7).
    Journal of applied toxicology : JAT, 2018, Volume: 38, Issue:7

    Topics: Butylated Hydroxyanisole; Butylated Hydroxytoluene; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Endocrine Disruptors; Estradiol; Estrogen Receptor Modulators; Estrogens; Female; Humans; Inhibitory Concentration 50; MCF-7 Cells; Models, Biological; Parabens; Propyl Gallate; Risk Assessment

2018
Pancreatic beta cells are a sensitive target of embryonic exposure to butylparaben in zebrafish (Danio rerio).
    Birth defects research, 2018, 07-03, Volume: 110, Issue:11

    Topics: Animals; Cysteine; Embryo, Nonmammalian; Environmental Exposure; Gene Expression Regulation, Developmental; Glutathione; Insulin-Secreting Cells; Larva; Oxidation-Reduction; Parabens; Toxicity Tests; Zebrafish

2018
Biodegradation of four selected parabens with aerobic activated sludge and their transesterification product.
    Ecotoxicology and environmental safety, 2018, Jul-30, Volume: 156

    Topics: Adsorption; Biodegradation, Environmental; Cosmetics; Esterification; Food Preservatives; Kinetics; Parabens; Preservatives, Pharmaceutical; Sewage; Water Pollutants, Chemical

2018
Survey of selected personal care products in surface water of coral reefs in Kenting National Park, Taiwan.
    The Science of the total environment, 2018, Sep-01, Volume: 635

    Topics: Benzophenones; Coral Reefs; Environmental Monitoring; Parabens; Parks, Recreational; Seawater; Taiwan; Triclosan; Water Pollutants, Chemical

2018
Effects of parabens on antioxidant system and oxidative damages in Nile tilapia (Oreochromis niloticus).
    Ecotoxicology and environmental safety, 2018, Oct-30, Volume: 162

    Topics: Animals; Biomarkers; Catalase; Cichlids; Gills; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Lipid Peroxidation; Liver; Male; Malondialdehyde; Oxidative Stress; Parabens; Superoxide Dismutase; Toxicity Tests, Acute

2018
Addendum: Solvation Energies of Butylparaben, Benzo[a]pyrene diol epoxide, Perfluorooctanesulfonic acid, and DEHP in Complex with DNA Bases.
    Chemical research in toxicology, 2018, 08-20, Volume: 31, Issue:8

    Topics: Alkanesulfonic Acids; Benzo(a)pyrene; Diethylhexyl Phthalate; DNA; Epoxy Compounds; Fluorocarbons; Parabens; Phthalic Acids; Probability

2018
n-butylparaben exposure during perinatal period impairs fertility of the F1 generation female rats.
    Chemosphere, 2018, Volume: 213

    Topics: Animals; Endocrine Disruptors; Female; Fertility; Parabens; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley

2018
Skin Sensitization to Fluorescein Isothiocyanate Is Enhanced by Butyl Paraben in a Mouse Model.
    Biological & pharmaceutical bulletin, 2018, Dec-01, Volume: 41, Issue:12

    Topics: Animals; CHO Cells; Cricetinae; Cricetulus; Dermatitis, Contact; Dextrans; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Fluorescein-5-isothiocyanate; Mice; Mice, Inbred BALB C; Parabens

2018
Assessment of hepatotoxicity and dermal toxicity of butyl paraben and methyl paraben using HepG2 and HDFn in vitro models.
    Toxicology in vitro : an international journal published in association with BIBRA, 2019, Volume: 55

    Topics: Allergens; Cell Line; Cell Survival; Chemical and Drug Induced Liver Injury; Humans; Parabens; Skin; Toxicity Tests

2019
Biodegradation of methyl and butylparaben by bacterial strains isolated from amended and non-amended agricultural soil. Identification, behavior and enzyme activities of microorganisms.
    Journal of environmental management, 2019, Sep-01, Volume: 245

    Topics: Bacteria; Parabens; RNA, Ribosomal, 16S; Sewage; Soil; Soil Microbiology; Soil Pollutants

2019
Traces of intact paraben molecules in endometrial carcinoma.
    Environmental science and pollution research international, 2019, Volume: 26, Issue:30

    Topics: Adult; Case-Control Studies; Chromatography, Liquid; Endometrial Neoplasms; Environmental Pollutants; Female; Humans; Middle Aged; Parabens; Tandem Mass Spectrometry; Turkey; Uterine Cervical Dysplasia; Uterine Cervical Neoplasms

2019
Probabilistic exposure assessment of aggregate rates of dermal exposure of Japanese women and children to parabens in personal care products.
    Chemosphere, 2020, Volume: 239

    Topics: Administration, Cutaneous; Adult; Child, Preschool; Cosmetics; Female; Genitalia; Humans; Infant; Japan; Parabens; Preservatives, Pharmaceutical; Risk Assessment; Young Adult

2020
Parabens in breast milk and possible sources of exposure among lactating women in Korea.
    Environmental pollution (Barking, Essex : 1987), 2019, Volume: 255, Issue:Pt 2

    Topics: Adult; Breast Feeding; Child; Child, Preschool; Colostrum; Cosmetics; Demography; Environmental Pollutants; Female; Humans; Infant; Infant, Newborn; Lactation; Maternal Exposure; Milk, Human; Parabens; Pregnancy; Preservatives, Pharmaceutical; Regression Analysis; Republic of Korea; Young Adult

2019
Enhancement of paraben-fungicidal activity by sulforaphane, a cruciferous vegetable-derived isothiocyanate, via membrane structural damage in Saccharomyces cerevisiae.
    Letters in applied microbiology, 2019, Volume: 69, Issue:6

    Topics: Allergens; Animals; Antifungal Agents; Cosmetics; Drug Synergism; Female; Humans; Isothiocyanates; Parabens; Preservatives, Pharmaceutical; Saccharomyces cerevisiae; Sulfoxides; Vegetables

2019
Nanocrystalline ferrihydrite activated peroxymonosulfate for butyl-4-hydroxybenzoate oxidation: Performance and mechanism.
    Chemosphere, 2020, Volume: 242

    Topics: Catalysis; Ferric Compounds; Kinetics; Models, Chemical; Oxidation-Reduction; Parabens; Peroxides; Reactive Oxygen Species

2020
n-Butylparaben exposure through gestation and lactation impairs spermatogenesis and steroidogenesis causing reduced fertility in the F1 generation male rats.
    Environmental pollution (Barking, Essex : 1987), 2020, Volume: 256

    Topics: Animals; Dose-Response Relationship, Drug; Endocrine Disruptors; Female; Fertility; Gene Expression Regulation, Developmental; Lactation; Leydig Cells; Male; Parabens; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Receptors, Steroid; Sexual Maturation; Sperm Count; Spermatogenesis; Spermatozoa; Testis

2020
Combined effect of silver nanoparticles and aluminium chloride, butylparaben or diethylphthalate on the malignancy of MDA-MB-231 breast cancer cells and tumor-specific immune responses of human macrophages and monocyte-derived dendritic cells.
    Toxicology in vitro : an international journal published in association with BIBRA, 2020, Volume: 65

    Topics: Aluminum Chloride; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cosmetics; Dendritic Cells; Drug Interactions; Gene Expression; Humans; Macrophages; Metal Nanoparticles; Monocytes; Parabens; Phagocytosis; Phthalic Acids; Silver

2020
Effects of Butylparaben Supplementation on In Vitro Development of Mouse Preantral Follicle.
    Reproductive sciences (Thousand Oaks, Calif.), 2020, Volume: 27, Issue:6

    Topics: Animals; Caspase 3; Estradiol; Extracellular Signal-Regulated MAP Kinases; Female; In Vitro Oocyte Maturation Techniques; Mice; Oocytes; Ovarian Follicle; Parabens; Phosphoproteins; Superoxide Dismutase

2020
Paraben concentrations found in human body fluids do not exert steroidogenic effects in human granulosa primary cell cultures.
    Toxicology mechanisms and methods, 2020, Volume: 30, Issue:5

    Topics: Adult; Aromatase; Body Fluids; Cells, Cultured; Cholesterol Side-Chain Cleavage Enzyme; DNA, Mitochondrial; Dose-Response Relationship, Drug; Endocrine Disruptors; Estradiol Dehydrogenases; Female; Granulosa Cells; Humans; Mitochondria; Models, Biological; Multienzyme Complexes; Parabens; Primary Cell Culture; Progesterone; Progesterone Reductase; Steroid Isomerases

2020
Butylparaben Is Toxic to Porcine Oocyte Maturation and Subsequent Embryonic Development Following In Vitro Fertilization.
    International journal of molecular sciences, 2020, May-24, Volume: 21, Issue:10

    Topics: Animals; Blastocyst; Embryonic Development; Fertilization in Vitro; Glutathione; Oocytes; Oogenesis; Parabens; Reactive Oxygen Species; Sus scrofa

2020
Parabens inhibit hNa
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020, Volume: 128

    Topics: Dose-Response Relationship, Drug; HEK293 Cells; Humans; Membrane Potentials; Molecular Structure; NAV1.2 Voltage-Gated Sodium Channel; Parabens; Structure-Activity Relationship; Voltage-Gated Sodium Channel Blockers

2020
Urinary Concentrations of Parabens in a Population of Iranian Adolescent and Their Association with Sociodemographic Indicators.
    Archives of environmental contamination and toxicology, 2020, Volume: 79, Issue:2

    Topics: Adolescent; Cosmetics; Endocrine Disruptors; Environmental Exposure; Environmental Pollutants; Female; Humans; Iran; Male; Parabens; Preservatives, Pharmaceutical

2020
Butylparaben multigenerational reproductive assessment by continuous breeding in Hsd:Sprague Dawley SD rats following dietary exposure.
    Reproductive toxicology (Elmsford, N.Y.), 2020, Volume: 96

    Topics: Animals; Anti-Infective Agents; Dietary Exposure; Female; Liver; Male; Maternal-Fetal Exchange; Parabens; Pregnancy; Rats, Sprague-Dawley; Reproduction; Sexual Maturation

2020
Effects of butylparaben exposure on thyroid peroxidase (TPO) and type 1 iodothyronine deiodinase (D1) in female Wistar rats.
    Toxicology, 2020, Volume: 443

    Topics: Animals; Endocrine Disruptors; Female; Iodide Peroxidase; Kidney; Parabens; Rats, Wistar; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine

2020
Dietary Habits and Personal Care Product Use as Predictors of Urinary Concentrations of Parabens in Iranian Adolescents.
    Environmental toxicology and chemistry, 2020, Volume: 39, Issue:12

    Topics: Adolescent; Cosmetics; Endocrine Disruptors; Feeding Behavior; Food; Humans; Iran; Male; Parabens; Sunscreening Agents

2020
Toxicological assessment and developmental abnormalities induced by butylparaben and ethylparaben exposure in zebrafish early-life stages.
    Environmental toxicology and pharmacology, 2020, Volume: 80

    Topics: Animals; Behavior, Animal; Blood Circulation; Edema; Embryo, Nonmammalian; Female; Hemostasis; Larva; Lethal Dose 50; Male; Notochord; Parabens; Pericardium; Water Pollutants, Chemical; Yolk Sac; Zebrafish

2020
Abnormal steroidogenesis, oxidative stress, and reprotoxicity following prepubertal exposure to butylparaben in mice and protective effect of Curcuma longa.
    Environmental science and pollution research international, 2021, Volume: 28, Issue:5

    Topics: Animals; Antioxidants; Curcuma; Female; Male; Mice; Oxidative Stress; Parabens

2021
Prenatal Exposure to Butyl Paraben Is Associated With Fat Percentage in 7-Year-Old Boys.
    The Journal of clinical endocrinology and metabolism, 2021, 06-16, Volume: 106, Issue:7

    Topics: Absorptiometry, Photon; Adipose Tissue; Child; Cohort Studies; Endocrine Disruptors; Female; Humans; Male; Maternal Exposure; Parabens; Pediatric Obesity; Pregnancy; Prenatal Exposure Delayed Effects

2021
HPLC method development/validation and skin diffusion study of caffeine, methyl paraben and butyl paraben as skin-diffusing model drugs.
    PloS one, 2021, Volume: 16, Issue:3

    Topics: Administration, Cutaneous; Caffeine; Chromatography, High Pressure Liquid; Humans; Parabens; Skin; Skin Absorption

2021
Behavioural effects of early-life exposure to parabens in zebrafish larvae.
    Journal of applied toxicology : JAT, 2021, Volume: 41, Issue:11

    Topics: Animals; Endocrine Disruptors; Larva; Parabens; Zebrafish

2021
Thirteen-week subcutaneous repeated dose toxicity study of butylparaben and its toxicokinetics in rats.
    Archives of toxicology, 2021, Volume: 95, Issue:6

    Topics: Animals; Dose-Response Relationship, Drug; Estrous Cycle; Female; Injections, Subcutaneous; Male; No-Observed-Adverse-Effect Level; Parabens; Preservatives, Pharmaceutical; Rats; Rats, Sprague-Dawley; Semen; Sex Factors; Toxicokinetics

2021
Assessment of butylparaben (4-hydroxybenzoic acid butyl ester)-assisted heat treatment against Escherichia coli O157:H7 and Salmonella enterica serotype Typhimurium in meat and bone meal.
    Journal of food science, 2021, Volume: 86, Issue:6

    Topics: Biological Products; Colony Count, Microbial; Escherichia coli O157; Food Microbiology; Hot Temperature; Meat; Minerals; Parabens; Salmonella typhimurium

2021
Butylparaben Induces the Neuronal Death Through the ER Stress-Mediated Apoptosis of Primary Cortical Neurons.
    Neurotoxicity research, 2022, Volume: 40, Issue:1

    Topics: Apoptosis; Endoplasmic Reticulum Stress; Neurons; Parabens

2022
Embryonic exposure to butylparaben and propylparaben induced developmental toxicity and triggered anxiety-like neurobehavioral response associated with oxidative stress and apoptosis in the head of zebrafish larvae.
    Environmental toxicology, 2022, Volume: 37, Issue:8

    Topics: Acetylcholinesterase; Animals; Antioxidants; Anxiety; Apoptosis; Embryo, Nonmammalian; Glutathione; Larva; Neurodegenerative Diseases; Oxidative Stress; Parabens; Reactive Oxygen Species; Zebrafish

2022
Comparative cytotoxicity induced by parabens and their halogenated byproducts in human and fish cell lines.
    Drug and chemical toxicology, 2023, Volume: 46, Issue:4

    Topics: Animals; Cell Line; Humans; Mammals; Parabens

2023
Prenatal paraben exposures and birth size: Sex-specific associations in a healthy population - A study from the Odense Child Cohort.
    The Science of the total environment, 2023, Apr-15, Volume: 869

    Topics: Birth Weight; Female; Humans; Male; Parabens; Pregnancy; Prospective Studies

2023
Disparate toxicity mechanisms of parabens with different alkyl chain length in freshwater biofilms: Ecological hazards associated with antibiotic resistome.
    The Science of the total environment, 2023, Jul-10, Volume: 881

    Topics: Apoptosis; Fresh Water; Parabens

2023
Exposure to parabens and dysglycemia: Insights from a Chinese population.
    Chemosphere, 2023, Volume: 340

    Topics: Bayes Theorem; Case-Control Studies; Cohort Studies; Diabetes Mellitus, Type 2; East Asian People; Glucose; Humans; Parabens

2023
Butylparaben promotes phosphatidylserine exposure and procoagulant activity of human red blood cells via increase of intracellular calcium levels.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2023, Volume: 181

    Topics: Calcium; Endothelial Cells; Erythrocytes; Humans; Parabens; Phosphatidylserines; Thrombin

2023
Cardio- and neuro-toxic effects of four parabens on Daphnia magna.
    Ecotoxicology and environmental safety, 2023, Volume: 268

    Topics: Animals; Cardiomyopathies; Daphnia; Ecosystem; Humans; Parabens

2023