propranolol has been researched along with tolbutamide in 76 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 46 (60.53) | 18.7374 |
| 1990's | 3 (3.95) | 18.2507 |
| 2000's | 9 (11.84) | 29.6817 |
| 2010's | 18 (23.68) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
| Carrupt, PA; Martel, S; Ottaviani, G | 1 |
| Abraham, MH; Acree, WE; Ibrahim, A | 1 |
| Briand, X; Faller, B; Lázaro, E; Lowe, PJ | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Boriss, H; Braggio, S; Corbioli, S; Fontana, S; Helmdach, L; Longhi, R; Schiller, J; Vinco, F | 1 |
| Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S | 1 |
| Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
| Bending, MR; Dollery, CT; Kahn, GC; Mucklow, JC | 1 |
| Curzon, G; Fernando, JC | 1 |
| Savage, RL | 1 |
| Chertow, BS; Fariss, BL; Schikman, CH | 1 |
| Christensen, LK; Hansen, JM | 1 |
| Day, JA; Patel, YC; Ramseur, R; Samols, E; Weir, GC | 1 |
| Anderson, JH; Blackard, WG; Spitzer, JJ | 1 |
| Blackard, WG; Kikuchi, M; Rabinovitch, A; Renold, AE | 1 |
| Koene, R; Wijdeveld, P | 1 |
| Garrino, MG; Henquin, JC | 1 |
| Pfeifer, MA; Rothschild, AH; Rothschild, MA | 1 |
| Hanano, M; Iga, T; Sawada, Y; Sugiyama, Y | 1 |
| Pattavina, CG; Podolsky, S | 1 |
| Ikeda, M | 1 |
| Hodgins, DS; Kuo, JF; Kuo, WN | 1 |
| De Divitiis, O; Gallo, B; Giordano, F; Jacono, A | 1 |
| Loubatières, A; Loubatières-Mariani, MM | 1 |
| Loubatiéres, A; Mariani, MM | 1 |
| Chapal, J; Loubathières, A; Mariani, MM; Ribes, G | 1 |
| Brendel, K; Bressler, R; Cordon, MV | 1 |
| Brendel, K; Bressler, R; Vargas-Cordon, M | 1 |
| Bressler, R; Kizer, JS | 1 |
| Cerasi, E; Luft, R | 1 |
| Anderson, JH; Blackard, WG; Byrd, GW | 1 |
| Lasseter, KC; Levey, GS; McCarthy, JS; Palmer, RF | 1 |
| Albanese, MC; Alibrando, S; Allegra, V; Carducci Artenisio, A; Caruso, A; Corsi, V; Sprovieri, M | 1 |
| Bayeli, PF; Giovannelli, G; Meschino, S; Montagnani, M | 1 |
| Feldman, JM; Lebovitz, HE; Quickel, KE | 1 |
| Seltzer, HS | 1 |
| Cerasi, E; Widström, A | 1 |
| Albanese, MC; Alibrando, S; Allegra, V; Carducci Artenisio, A; Corsi, V; Ragonese, F; Sprovieri, M | 1 |
| Albanese, MC; Allegra, V; Carducci Artenisio, A; Corsi, V; Ragonese, F; Sprovieri, M | 1 |
| Beyer, J; Cordes, U; Haupt, E; Köberich, W; Schöffling, K | 1 |
| Camanni, F; Massara, F; Molinatti, GM; Strumia, E | 1 |
| Dzindzio, B; Ettinger, PO; Oldewurtel, HA; Regan, TJ; Sethi, V | 1 |
| Ettinger, PO; Oldewurtel, HA; Regan, TJ; Sethi, V | 1 |
| Fratino, P; Gamba, G; Specchia, G | 1 |
| Kowalski, S; Wolański, A | 1 |
| Delzant, G; Modigliani, E; Strauch, G | 1 |
| Erill, S | 1 |
| Lillywhite, KJ; Miners, JO; Smith, KJ; Wing, LM | 1 |
| Nezu, E; Yoneyama, T; Yoshimura, K | 1 |
| Burnett, MA; Lang, DA; Matthews, DR; Turner, RC | 1 |
| Hjelle, JJ; Petersen, DR | 1 |
| Groop, LC; Tötterman, KJ | 1 |
| Groop, L; Tötterman, KJ | 1 |
| Lux, G; Rösch, W | 1 |
| Chiba, K; Echizen, H; Ishizaki, T; Tani, M; Yoshimoto, K | 1 |
| Ikuta, M; Kuhara, T; Oda, S; Ohneda, A; Sasaki, Y | 1 |
| Aiba, T; Horiuchi, M; Kurosaki, Y; Moriyama, S; Takahata, Y | 1 |
6 review(s) available for propranolol and tolbutamide
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Drugs and breast milk.
Topics: Analgesics; Anti-Bacterial Agents; Anti-Inflammatory Agents; Anticoagulants; Anticonvulsants; Cyclophosphamide; Female; Hormones; Humans; Infant Nutritional Physiological Phenomena; Infant, Newborn; Iodides; Male; Methotrexate; Milk, Human; Narcotics; Pharmaceutical Preparations; Propranolol; Psychotropic Drugs; Sulfonamides; Theophylline; Thiouracil; Tolbutamide | 1977 |
Drug interactions with oral sulphonylurea hypoglycaemic drugs.
Topics: Allopurinol; Analgesics; Anticoagulants; Chloramphenicol; Chlorpropamide; Disulfiram; Drug Interactions; Ethanol; Glyburide; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Kinetics; Monoamine Oxidase Inhibitors; Novobiocin; Phenylbutazone; Phenytoin; Probenecid; Propranolol; Rifampin; Sulfonamides; Sulfonylurea Compounds; Tolbutamide | 1977 |
Prediction of the disposition of nine weakly acidic and six weakly basic drugs in humans from pharmacokinetic parameters in rats.
Topics: Animals; Antipyrine; Barbiturates; Biological Availability; Chlorpromazine; Diazepam; Drug Evaluation; Female; Half-Life; Humans; Kinetics; Male; Metabolic Clearance Rate; Pentazocine; Pharmaceutical Preparations; Phenylbutazone; Phenytoin; Propranolol; Quinidine; Rats; Species Specificity; Tissue Distribution; Tolbutamide; Valproic Acid; Warfarin | 1985 |
Drugs and the mechanism of insulin secretion.
Topics: Adrenocorticotropic Hormone; Amino Acids; Animals; Cyclic AMP; Diabetes Mellitus; Fatty Acids, Nonesterified; Glucagon; Glucose; Hexoses; Humans; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Ketone Bodies; Norepinephrine; Ouabain; Pancreas; Potassium; Propranolol; Rabbits; Rats; Thyrotropin; Tolbutamide | 1969 |
Drug-induced hypoglycemia. A review based on 473 cases.
Topics: Acetohexamide; Adolescent; Adult; Aminobenzoates; Child; Child, Preschool; Chlorpropamide; Coma; Edetic Acid; Ethanol; Female; Humans; Hypoglycemia; Hypoglycemic Agents; Infant; Infant, Newborn; Insulin; Male; Manganese; Middle Aged; Nutritional Physiological Phenomena; Oxytetracycline; Propranolol; Salicylates; Sulfonylurea Compounds; Tolbutamide | 1972 |
2 trial(s) available for propranolol and tolbutamide
| Article | Year |
|---|---|
No effect of propranolol and metoprolol on tolbutamide-stimulated insulin-secretion in hypertensive diabetic and non-diabetic patients.
Topics: Clinical Trials as Topic; Diabetes Complications; Diabetes Mellitus; Double-Blind Method; Female; Humans; Hypertension; Insulin; Insulin Secretion; Male; Metoprolol; Middle Aged; Propanolamines; Propranolol; Tolbutamide | 1982 |
Propranolol does not inhibit sulphonylurea-stimulated insulin secretion in patients with non-insulin dependent diabetes mellitus.
Topics: Aged; Blood Glucose; C-Peptide; Clinical Trials as Topic; Diabetes Mellitus; Double-Blind Method; Female; Glipizide; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Male; Middle Aged; Propranolol; Random Allocation; Sulfonylurea Compounds; Tolbutamide | 1982 |
68 other study(ies) available for propranolol and tolbutamide
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
In silico and in vitro filters for the fast estimation of skin permeation and distribution of new chemical entities.
Topics: Humans; Membranes, Artificial; Models, Biological; Models, Molecular; Octanols; Permeability; Pharmaceutical Preparations; Skin Absorption; Water | 2007 |
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization | 2008 |
New approach to measure protein binding based on a parallel artificial membrane assay and human serum albumin.
Topics: Humans; Kinetics; Membranes, Artificial; Permeability; Protein Binding; Serum Albumin | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method.
Topics: Absorption; Albumins; Animals; Brain; Brain Chemistry; Cell Membrane; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; In Vitro Techniques; Lipids; Male; Microdialysis; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tissue Distribution | 2011 |
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors | 2012 |
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs.
Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests | 2012 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
Drug concentration in saliva.
Topics: Adolescent; Adult; Aged; Antipyrine; Chlorpropamide; Humans; Hydrogen-Ion Concentration; Male; Meperidine; Middle Aged; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Propranolol; Protein Binding; Saliva; Tolbutamide | 1978 |
Drugs altering insulin secretion: effects on plasma and brain concentrations of aromatic amino acids and on brain 5-hydroxytryptamine turnover.
Topics: Amino Acids; Animals; Brain Chemistry; Fatty Acids, Nonesterified; Hydroxyindoleacetic Acid; Insulin; Insulin Secretion; Male; Phentolamine; Phenylalanine; Propranolol; Rats; Serotonin; Streptozocin; Tolbutamide; Tryptophan; Tyrosine | 1977 |
Paradoxical enhancement of tolbutamide-induced insulin release by diazoxide in a patient with islet cell hyperplasia.
Topics: Blood Glucose; Child; Diazoxide; Glucagon; Glucose Tolerance Test; Humans; Hyperplasia; Hypoglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Male; Pancreatic Diseases; Propranolol; Tolbutamide | 1978 |
Modulation of pancreatic somatostatin by adrenergic and cholinergic agonism and by hyper- and hypoglycemic sulfonamides.
Topics: Acetylcholine; Animals; Diazoxide; Dogs; Epinephrine; Glucagon; Insulin; Insulin Secretion; Isoproterenol; Male; Pancreas; Phentolamine; Propranolol; Somatostatin; Sulfonamides; Tolbutamide | 1978 |
Hyperinsulinism in endotoxin shock dogs.
Topics: Alloxan; Animals; Blood Glucose; Dogs; Escherichia coli; Glucose; Hyperinsulinism; Islets of Langerhans; Propranolol; Receptors, Adrenergic; Shock, Septic; Tolbutamide | 1976 |
An effect of hyposmolarity on insulin release in vitro.
Topics: Amiloride; Amylases; Animals; Atropine; Calcium; Choline; Colchicine; Diazoxide; Epinephrine; Glucagon; Glucose; Hypotonic Solutions; Imidazoles; In Vitro Techniques; Insulin; Insulin Secretion; Male; Osmolar Concentration; Ouabain; Pancreas; Phentolamine; Phenytoin; Propranolol; Rats; Sorbitol; Tolbutamide; Trypsin Inhibitors; Vinblastine | 1975 |
[Diazoxide: new way in treatment of hypertension].
Topics: Adult; Chlorthalidone; Diazoxide; Diet, Sodium-Restricted; Female; Humans; Hydralazine; Hypertension; Male; Methyldopa; Middle Aged; Propranolol; Tolbutamide; Water-Electrolyte Balance | 1975 |
B cell adrenoceptors and sulphonylurea-induced insulin release in mouse islets.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Female; Glyburide; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Metoprolol; Mice; Mice, Inbred Strains; Propanolamines; Propranolol; Receptors, Adrenergic, beta; Tolbutamide | 1990 |
The inotropic action of tolbutamide and glyburide.
Topics: Administration, Oral; Adult; Blood Glucose; Blood Pressure; Dobutamine; Epinephrine; Glyburide; Humans; Male; Myocardial Contraction; Norepinephrine; Propranolol; Stroke Volume; Tolbutamide | 1989 |
Hyperosmolar nonketotic diabetic coma: a complication of propranolol therapy.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Diabetes Complications; Diabetes Mellitus; Diabetic Coma; Glucose Tolerance Test; Humans; Hypertension; Injections, Intravenous; Insulin; Male; Middle Aged; Propranolol; Tolbutamide | 1973 |
[Plasma insulin levels in endocrine diseases. 4. Effects of adrenergic receptor agents on plasma insulin levels].
Topics: Adolescent; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Arginine; Depression, Chemical; Epinephrine; Female; Humans; Insulin; Isoproterenol; Male; Methoxamine; Phenoxybenzamine; Phentolamine; Phenylephrine; Propranolol; Receptors, Adrenergic; Stimulation, Chemical; Sympatholytics; Sympathomimetics; Tolbutamide | 1973 |
Regulation by various hormones and agents of adenosine-3',5'-monophosphate levels in islets of Langerhans of rats.
Topics: Adenine; Adrenergic beta-Antagonists; Adrenocorticotropic Hormone; Animals; Cresols; Cyclic AMP; Epinephrine; Glucagon; Glucose; Guanosine Triphosphate; Hormones; In Vitro Techniques; Islets of Langerhans; Isoproterenol; Leucine; Phenformin; Phenoxybenzamine; Phentolamine; Propanolamines; Propranolol; Propylamines; Prostaglandins; Rats; Receptors, Adrenergic; Secretin; Sotalol; Theophylline; Thyrotropin; Tolbutamide; Tritium | 1974 |
Tolbutamide and propranolol.
Topics: Blood Glucose; Humans; Insulin; Insulin Secretion; Propranolol; Tolbutamide | 1968 |
In vitro secretion of insulin after glucose, sulphonylureas, adrenergic and cholinergic substances studied by isolated perfused rat pancreas.
Topics: Acetylcholine; Animals; Atropine; Diazoxide; Epinephrine; Glucagon; Glucose; Glyburide; Heptoses; In Vitro Techniques; Insulin; Insulin Secretion; Isoproterenol; Ketoses; Norepinephrine; Pancreas; Parasympathomimetics; Perfusion; Phenoxybenzamine; Practolol; Propranolol; Sulfonylurea Compounds; Theophylline; Tolbutamide | 1974 |
[Recent pharmacologic aspects of sulfamides modifying insulin secretion (hypoglycemic and hyperglycemic sulfamides)].
Topics: Animals; Catecholamines; Diazoxide; Dogs; Dose-Response Relationship, Drug; Drug Antagonism; Drug Synergism; Glucose; Glyburide; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Isoproterenol; Pancreas; Pancreatectomy; Phenoxybenzamine; Propranolol; Rats; Tolbutamide | 1973 |
[Propranolol and hypoglycemic sulfonamides. Study on insulin secretion and blood sugar].
Topics: Animals; Blood Glucose; Dogs; Drug Antagonism; Drug Synergism; Glyburide; Hypoglycemic Agents; Insulin; Insulin Secretion; Islets of Langerhans; Perfusion; Propranolol; Radioimmunoassay; Rats; Tolbutamide | 1971 |
Studies on the role of adenylcyclase in insulin secretion.
Topics: Adenine Nucleotides; Adenylyl Cyclases; Adrenocorticotropic Hormone; Anilides; Animals; Cyclic AMP; Enzymes; Glucagon; Glucose; Injections, Intravenous; Insulin; Insulin Secretion; Male; Mice; Propranolol; Stimulation, Chemical; Sulfonic Acids; Sympatholytics; Tolbutamide | 1969 |
Inhibition of insulin secretion by aryl-substituted secondary aminoethanols.
Topics: Adrenocorticotropic Hormone; Amino Alcohols; Animals; Blood Glucose; Cyclic AMP; Depression, Chemical; Glucagon; Glucose; Injections, Intraperitoneal; Injections, Intravenous; Insulin; Insulin Secretion; Male; Mice; Propranolol; Propylamines; Sulfanilamides; Sympatholytics; Tolbutamide | 1969 |
[Mechanism of insulin secretion with special regard to prediabetes].
Topics: Adenylyl Cyclases; Cyclic AMP; Glucose; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Pancreas; Prediabetic State; Propranolol; Theophylline; Tolbutamide | 1971 |
Hyperresponsiveness to tolbutamide of dogs pretreated with diazoxide.
Topics: Animals; Cyclic AMP; Depression, Chemical; Diazoxide; Dogs; Epinephrine; Insulin; Insulin Secretion; Propranolol; Radioimmunoassay; Secretory Rate; Stimulation, Chemical; Time Factors; Tolbutamide | 1971 |
The effect of sulfonylurea drugs on rabbit myocardial contractility, canine purkinje fiber automaticity, and adenyl cyclase activity from rabbit and human hearts.
Topics: Acetohexamide; Adenylyl Cyclases; Animals; Chlorpropamide; Culture Techniques; Cyclic AMP; Dogs; Heart; Heart Atria; Heart Conduction System; Humans; Membrane Potentials; Microelectrodes; Myocardium; Phenformin; Propranolol; Rabbits; Stimulation, Chemical; Sulfonylurea Compounds; Theophylline; Tolazamide; Tolbutamide | 1972 |
[Autonomic nervous system and secretion of insulin. II. Effect of adrenergic blockaders on the insulin secretion in response to tolbutamide].
Topics: Adult; Antigens; Autonomic Nervous System; Blood Glucose; Cyclic AMP; Female; Humans; Insulin; Insulin Antagonists; Insulin Secretion; Male; Middle Aged; Phentolamine; Propranolol; Tolbutamide | 1972 |
[Beta adrenergic receptors in hyperglycemia and in induced hypoglycemia].
Topics: Adrenergic beta-Antagonists; Adult; Blood Glucose; Fatty Acids, Nonesterified; Glucagon; Humans; Insulin; Male; Middle Aged; Propranolol; Sensory Receptor Cells; Sympathetic Nervous System; Tolbutamide | 1967 |
Potentiation of insulin secretion in vitro by serotonin antagonists.
Topics: Adrenergic alpha-Antagonists; Animals; Culture Techniques; Cyproheptadine; Dopamine; Fenclonine; Glucose; Haloperidol; Insulin; Insulin Secretion; Male; Methysergide; Pancreas; Phenoxybenzamine; Propranolol; Rabbits; Serotonin; Serotonin Antagonists; Stimulation, Chemical; Tolbutamide | 1972 |
On the action of tolbutamide in normal man. I. Role of adrenergic mechanisms in tolbutamide-induced insulin release during normoglycaemia and induced hypoglycaemia.
Topics: Adult; Blood Glucose; Catecholamines; Depression, Chemical; Feedback; Female; Humans; Hypoglycemia; Insulin; Male; Middle Aged; Phentolamine; Propranolol; Tolbutamide | 1973 |
[Autonomic nervous system and HCG secretion. II. Effect of adrenergic blockaders on the excretion of HCG following intravenous loading of tolbutamide].
Topics: Adult; Autonomic Nervous System; Blood Glucose; Chorionic Gonadotropin; Fatty Acids, Nonesterified; Growth Hormone; Humans; Injections, Intravenous; Middle Aged; Phentolamine; Propranolol; Stimulation, Chemical; Tolbutamide | 1973 |
Effects of propranolol on HGH secretion after endovenous tolbutamide load in obese subjects.
Topics: Adult; Aged; Blood Glucose; Fatty Acids, Nonesterified; Growth Hormone; Humans; Middle Aged; Obesity; Propranolol; Radioimmunoassay; Time Factors; Tolbutamide | 1973 |
[Changes of blood sugar, serum insulin and free fatty acids following tolbutamide and glibenclamide in subjects of normal metabolism, pretreated with alpha and beta receptor blockaders].
Topics: Blood Glucose; Fatty Acids, Nonesterified; Glyburide; Humans; Insulin; Phentolamine; Propranolol; Tolbutamide | 1971 |
Depressed tolbutamide-induced insulin response in subjects treated with propranolol.
Topics: Administration, Oral; Adult; Blood Glucose; Depression, Chemical; Female; Humans; Injections, Intravenous; Insulin; Insulin Secretion; Male; Middle Aged; Propranolol; Tolbutamide | 1971 |
Glucose intolerance in nonischemic cardiac disease. Role of cardiac output and adrenergic function.
Topics: Adolescent; Adult; Aged; Cardiac Output; Cardiomyopathies; Cardiomyopathy, Hypertrophic; Female; Glucose; Glucose Tolerance Test; Heart Diseases; Humans; Insulin; Insulin Secretion; Male; Metabolic Diseases; Middle Aged; Pericarditis, Constrictive; Phenoxybenzamine; Propranolol; Sympathetic Nervous System; Tolbutamide | 1971 |
Glucose intolerance in cardiac patients without myocardial ischemia and its relation tto cardiac output.
Topics: Adolescent; Adult; Aged; Cardiac Catheterization; Cardiac Output; Cardiomyopathies; Coronary Disease; Glucose; Glucose Tolerance Test; Heart; Heart Valve Diseases; Humans; Middle Aged; Pancreas; Phenoxybenzamine; Propranolol; Regional Blood Flow; Sympathetic Nervous System; Tolbutamide | 1971 |
[Influence of propranolol on the action of tolbutamide].
Topics: Adult; Blood Glucose; Diabetes Mellitus; Humans; Insulin; Pancreas; Propranolol; Tolbutamide | 1970 |
[Effect of propranolol on the hypoglycemic action of insulin and tolbutamide in diabetic patients].
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus; Female; Humans; Hypoglycemia; Insulin; Male; Middle Aged; Propranolol; Tolbutamide | 1969 |
[Insulin secretion study during arginine perfusion. Comparative effects of sympatholytics in normal subjects and hyperthyroid patients].
Topics: Adult; Aged; Arginine; Blood Glucose; Catecholamines; Diabetes Complications; Epinephrine; Glucose; Guanethidine; Humans; Hyperthyroidism; Insulin; Insulin Secretion; Middle Aged; Perfusion; Phentolamine; Propranolol; Proteins; Radioimmunoassay; Thyroid Hormones; Tolbutamide | 1969 |
Persistence of the hypoglycemic effect of tolbutamide after block of beta-adrenergic receptors.
Topics: Animals; Blood Glucose; Depression, Chemical; Electrocardiography; Propranolol; Rabbits; Tolbutamide | 1969 |
Failure of 'therapeutic' doses of beta-adrenoceptor antagonists to alter the disposition of tolbutamide and lignocaine.
Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Blood Proteins; Drug Interactions; Female; Humans; Lidocaine; Male; Metoprolol; Oxidation-Reduction; Propranolol; Protein Binding; Tolbutamide | 1984 |
Stimulation of cyclic AMP-dependent protein kinase by catecholamines and its relationship to alpha-amylase release in rat parotid gland.
Topics: 1-Methyl-3-isobutylxanthine; alpha-Amylases; Alprenolol; Amylases; Animals; Catecholamines; Cyclic AMP; Enzyme Activation; In Vitro Techniques; Norepinephrine; Parotid Gland; Propranolol; Protein Kinases; Rats; Rats, Inbred Strains; Tolbutamide | 1982 |
Control of pulsatile insulin secretion in man.
Topics: Adult; Aged; Atropine; Blood Glucose; Diabetes Mellitus; Female; Glucose; Humans; Insulin; Insulin Secretion; Kinetics; Male; Middle Aged; Naloxone; Phentolamine; Propranolol; Sodium Salicylate; Tolbutamide; Vagotomy | 1983 |
Metabolic interactions of aldehyde dehydrogenase with therapeutic and toxic agents.
Topics: Alcohol Oxidoreductases; Alcoholism; Aldehyde Dehydrogenase; Aldehyde Oxidoreductases; Animals; Anti-Bacterial Agents; Benserazide; Carbon Tetrachloride; Chlorpropamide; Cyanamide; Disulfiram; Humans; Isoenzymes; Lactams; Liver; Malondialdehyde; Metronidazole; Pargyline; Pharmaceutical Preparations; Propranolol; Pyrogallol; Tolbutamide | 1982 |
[Drug therapy of gastrointestinal motility disorders].
Topics: Antacids; Atropine; Carbenoxolone; Colonic Diseases, Functional; Deglutition Disorders; Diarrhea; Dumping Syndrome; Gastroesophageal Reflux; Gastrointestinal Motility; Humans; Intestinal Diseases; Metoclopramide; Propranolol; Tolbutamide | 1980 |
Identification of human CYP isoforms involved in the metabolism of propranolol enantiomers--N-desisopropylation is mediated mainly by CYP1A2.
Topics: Aged; Benzoflavones; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Desipramine; Ditiocarb; Female; Humans; Hydroxylation; In Vitro Techniques; Isoenzymes; Male; Mephenytoin; Microsomes, Liver; Middle Aged; Oxazines; Phenacetin; Propranolol; Quinidine; Recombinant Proteins; Stereoisomerism; Substrate Specificity; Sulfaphenazole; Tolbutamide; Troleandomycin | 1995 |
Insulin and glucagon secretion in goats (Capra hircus Linnaeus) exposed to cold.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Arginine; Butyrates; Butyric Acid; Cold Temperature; Female; Glucagon; Glucose; Goats; Infusions, Intravenous; Insulin; Insulin Secretion; Phentolamine; Propranolol; Tolbutamide | 1995 |
Effects of peritoneal dialysis on pharmacotherapy: a deductive pharmacokinetic-model approach to predict drug concentration profiles in plasma and peritoneal fluid.
Topics: Acute Kidney Injury; Animals; Ascitic Fluid; Cefazolin; Disease Models, Animal; Male; Models, Biological; Peritoneal Dialysis; Propranolol; Protein Binding; Rats, Wistar; Reproducibility of Results; Tolbutamide | 2014 |