Page last updated: 2024-08-16

propranolol and pirenzepine

propranolol has been researched along with pirenzepine in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19907 (29.17)18.7374
1990's7 (29.17)18.2507
2000's7 (29.17)29.6817
2010's3 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Akamatsu, M1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Biggs, DF; Yang, ZJ1
Horne, C; Mutschler, E; Palm, D; Pitschner, HF; Schulte, B; Volz-Zang, C; Wellstein, A1
Baskin, SI; Thomsen, RH1
Jaiswal, N; Malik, KU1
O'Donnell, ME1
Palm, D; Pitschner, HF; Schlepper, M; Schulte, B; Wellstein, A1
Anderson, W; Dickinson, KE; Hirschowitz, BI; Matsumoto, H; Pruitt, RE; Uemura, N1
Morrow, C; Murphy, S; Pearce, B1
Pitschner, HF; Wellstein, A1
Ishii, K; Kato, R1
Matsumoto, S1
Fleischhacker, WW; Hummer, M; Kohl, C; Kurzthaler, I; Miller, C1
Endou, M; Okumura, F; Tanito, Y1
García-Sacristán, A; Prieto, D; Simonsen, U; Triguero, D1
Fujiwara, Y; Hamamura, T; Kuroda, S; Lee, Y; Ohashi, K; Suzuki, H1
Giglio, D; Götrick, B; Tobin, G1
Aronsson, P; Eriksson, L; Giglio, D; Tobin, G1

Other Studies

24 other study(ies) available for propranolol and pirenzepine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water

2001
QSAR study on permeability of hydrophobic compounds with artificial membranes.
    Bioorganic & medicinal chemistry, 2007, Jun-01, Volume: 15, Issue:11

    Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship

2007
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Importance of physicochemical properties for the design of new pesticides.
    Journal of agricultural and food chemistry, 2011, Apr-13, Volume: 59, Issue:7

    Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Muscarinic-receptor functioning in tracheas from normal and ovalbumin-sensitive guinea pigs.
    Canadian journal of physiology and pharmacology, 1991, Volume: 69, Issue:6

    Topics: Aerosols; Animals; Asthma; Bethanidine; Electric Stimulation; Female; Gallamine Triethiodide; Guinea Pigs; Histamine; Hypersensitivity; In Vitro Techniques; Indomethacin; Methacholine Compounds; Ovalbumin; Pirenzepine; Propranolol; Receptors, Muscarinic; Trachea; Yohimbine

1991
AF-DX 116, a cardioselective muscarinic antagonist in humans: pharmacodynamic and pharmacokinetic properties.
    Clinical pharmacology and therapeutics, 1991, Volume: 50, Issue:4

    Topics: Adult; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Female; Heart Rate; Humans; Male; Parasympatholytics; Pirenzepine; Propranolol; Random Allocation; Receptors, Muscarinic; Reference Values; Salivation

1991
The effects of AF-DX 116, a cardioselective muscarinic antagonist, on the negative inotropic action of acetylcholine.
    Research communications in chemical pathology and pharmacology, 1991, Volume: 71, Issue:1

    Topics: Acetylcholine; Animals; Dose-Response Relationship, Drug; Drug Interactions; Guinea Pigs; In Vitro Techniques; Male; Myocardial Contraction; Pirenzepine; Propranolol; Rabbits; Rats; Receptors, Muscarinic

1991
Prostaglandin synthesis elicited by cholinergic stimuli is mediated by activation of M2 muscarinic receptors in rabbit heart.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 245, Issue:1

    Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Animals; Arachidonic Acid; Arachidonic Acids; Arecoline; Heart; Heart Rate; Hexamethonium Compounds; Indomethacin; Male; Myocardium; Phentolamine; Pirenzepine; Propranolol; Prostaglandins; Rabbits; Receptors, Muscarinic

1988
Regulation of Na-K-Cl cotransport in endothelial cells by atrial natriuretic factor.
    The American journal of physiology, 1989, Volume: 257, Issue:1 Pt 1

    Topics: Acetylcholine; Animals; Aorta, Thoracic; Atrial Natriuretic Factor; Biological Transport; Cattle; Cells, Cultured; Chlorides; Cimetidine; Cyclic GMP; Endothelium, Vascular; Histamine; Kinetics; Norepinephrine; Pirenzepine; Potassium; Propranolol; Receptors, Adrenergic, beta; Receptors, Histamine H2; Receptors, Muscarinic; Second Messenger Systems; Sodium

1989
AF-DX 116 discriminates heart from gland M2-cholinoceptors in man.
    Life sciences, 1989, Volume: 45, Issue:6

    Topics: Adult; Animals; Atropine; Blood Pressure; Cattle; Cell Membrane; Cerebral Cortex; Heart Rate; Humans; Kinetics; Male; Myocardium; N-Methylscopolamine; Organ Specificity; Pirenzepine; Propranolol; Receptors, Cholinergic; Reference Values; Saliva; Salivary Glands; Scopolamine Derivatives; Swine

1989
Muscarinic cholinergic receptor subtype on frog esophageal peptic cells: binding and secretion studies.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 246, Issue:3

    Topics: Acetylcholine; Animals; Atropine; Bethanechol; Bethanechol Compounds; Carbachol; Esophagus; Imipramine; Kinetics; N-Methylscopolamine; Oxotremorine; Pepsinogens; Pirenzepine; Propranolol; Radioligand Assay; Rana catesbeiana; Receptors, Muscarinic; Scopolamine Derivatives

1988
Astrocytes have both M1 and M2 muscarinic receptor subtypes.
    Brain research, 1986, Jan-29, Volume: 364, Issue:1

    Topics: Animals; Astrocytes; Atropine; Benzodiazepinones; Carbachol; Cyclic AMP; Inositol; Isoproterenol; Phospholipids; Pirenzepine; Propranolol; Rats; Receptors, Muscarinic

1986
Complex dose-response curves of atropine in man explained by different functions of M1- and M2-cholinoceptors.
    Naunyn-Schmiedeberg's archives of pharmacology, 1988, Volume: 338, Issue:1

    Topics: Adult; Animals; Atropine; Cattle; Dose-Response Relationship, Drug; Drug Interactions; Electrocardiography; Female; Half-Life; Heart Rate; Humans; In Vitro Techniques; Male; Pirenzepine; Propranolol; Rats; Receptors, Cholinergic; Salivary Glands; Salivation

1988
Suppression by muscarinic M2 stimulation of the contractile mechanism via histamine H1 receptors in the longitudinal muscle of guinea pig ileum.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:2

    Topics: Animals; Atropine; Calcium; Dose-Response Relationship, Drug; Female; Guinea Pigs; Histamine; Ileum; Male; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Phentolamine; Pirenzepine; Propranolol; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Temperature; Tetrodotoxin

1987
Functional evidence of excitatory M1 receptors in the rabbit airway.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 281, Issue:1

    Topics: Acetylcholine; Animals; Atropine; Bronchoconstriction; Female; Gallamine Triethiodide; Male; Mechanoreceptors; Pirenzepine; Propranolol; Rabbits; Receptor, Muscarinic M1; Receptors, Muscarinic; Vagus Nerve

1997
Propranolol treatment of olanzapine-induced akathisia.
    The American journal of psychiatry, 1997, Volume: 154, Issue:9

    Topics: Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Benzodiazepines; Drug Administration Schedule; Female; Humans; Infant; Olanzapine; Pirenzepine; Propranolol; Schizophrenia, Paranoid

1997
A comparison between chronotropic effects of neostigmine and edrophonium in isolated guinea pig right atrium.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 282, Issue:3

    Topics: Acetylcholine; Adenosine; Animals; Cholinesterase Inhibitors; Edrophonium; Electric Stimulation; Female; Guinea Pigs; Heart Atria; Heart Rate; In Vitro Techniques; Male; Neostigmine; Pirenzepine; Propranolol; Tetrodotoxin

1997
Cholinergic modulation of non-adrenergic, non-cholinergic relaxation in isolated, small coronary arteries from lambs.
    Pflugers Archiv : European journal of physiology, 1999, Volume: 438, Issue:2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholinesterase; Adrenergic alpha-Antagonists; Animals; Capsaicin; Choline O-Acetyltransferase; Coronary Vessels; Electric Stimulation; In Vitro Techniques; Microcirculation; Myography; Norepinephrine; Phentolamine; Physostigmine; Pirenzepine; Propranolol; Sheep; Suramin; Vasoconstrictor Agents; Vasodilation

1999
Clozapine- and olanzapine-induced Fos expression in the rat medial prefrontal cortex is mediated by beta-adrenoceptors.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2000, Volume: 23, Issue:2

    Topics: Adrenergic beta-Antagonists; Animals; Antipsychotic Agents; Benzodiazepines; Cell Count; Cell Nucleus; Clozapine; Locus Coeruleus; Male; Neurons; Olanzapine; Pirenzepine; Prefrontal Cortex; Propranolol; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Receptors, Adrenergic, beta

2000
Studies of muscarinic receptor subtypes in salivary gland function in anaesthetized rats.
    Autonomic neuroscience : basic & clinical, 2002, Sep-30, Volume: 100, Issue:1-2

    Topics: Acetylcholine; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Analysis of Variance; Anesthesia; Animals; Blood Pressure; Diamines; Dose-Response Relationship, Drug; Drug Interactions; Female; Muscarinic Antagonists; Parotid Gland; Phentolamine; Piperidines; Pirenzepine; Propranolol; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M3; Receptors, Muscarinic; Saliva; Salivary Glands; Sublingual Gland; Submandibular Gland; Vasodilator Agents

2002
In vitro characterization of parasympathetic and sympathetic responses in cyclophosphamide-induced cystitis in the rat.
    Basic & clinical pharmacology & toxicology, 2007, Volume: 100, Issue:2

    Topics: Adenosine Triphosphate; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Cyclophosphamide; Cystitis; Diamines; Electric Stimulation; In Vitro Techniques; Male; Muscarinic Antagonists; Muscle Contraction; Parasympatholytics; Phentolamine; Piperidines; Pirenzepine; Propranolol; Purinergic P2 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Suramin; Sympatholytics; Urinary Bladder

2007