Page last updated: 2024-08-16

propranolol and nortriptyline

propranolol has been researched along with nortriptyline in 46 studies

Research

Studies (46)

TimeframeStudies, this research(%)All Research%
pre-199015 (32.61)18.7374
1990's6 (13.04)18.2507
2000's10 (21.74)29.6817
2010's14 (30.43)24.3611
2020's1 (2.17)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Bergström, F; Giordanetto, F; Rehngren, M; Tunek, A; Wan, H1
Lombardo, F; Obach, RS; Waters, NJ1
Ahman, M; Holmén, AG; Wan, H1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Glen, RC; Lowe, R; Mitchell, JB1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Boriss, H; Braggio, S; Corbioli, S; Fontana, S; Helmdach, L; Longhi, R; Schiller, J; Vinco, F1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Dalvie, D; Loi, CM; Smith, DA1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Gabriel, E; Karobath, M; Lenz, G1
Prusiner, S; Raskin, NH1
Banaszkiewicz, W; Grzymislawska, I; Mrozikiewica, A1
Bertilsson, L; Kaneko, S; Otani, K1
Badia, A; Sallés, J; Vila, E1
Brockmeier, D; Ostrowski, J1
McMahon, T1
Goldstein, FJ; Malseed, RT; Rossi, GV1
Carrara, C; Garattini, S; Jori, A; Paglialunga, S1
Garattini, S; Jori, A; Paglialunga, S1
Thorstrand, C1
Riegelman, S1
König, J; Mlejnková, M; Rysánek, K; Spánková, H; Synek, P1
Gaffney, TE; Knapp, D; Privitera, P; Saelens, D; Walle, T1
Oates, JA; Shand, DG1
Hillard, JR; Vieweg, WV1
Neppe, VM1
Cosbey, SH; Craig, I; Gill, R1
Iruela, LM1
Abel, EL1
Fragala, MR; Richmond, DR; Sabaawi, M1
Aquino, CC; Domingues, RB; Domingues, SA; Kuster, GW; Silva, AL1
Furutani, K; Inanobe, A; Kurachi, Y; Ohno, Y; Yamakawa, Y1
Atzori, M; Basu, D; Dinh, L; Nichols, JA; Peña-Contreras, Z; Roychowdhury, S; Tam, J; Yadlapalli, A1
Donaldson, L; Dornhoffer, JR; Liu, YF; Macias, D; Rizk, HG1

Reviews

2 review(s) available for propranolol and nortriptyline

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for propranolol and nortriptyline

ArticleYear
A double-blind randomized controlled trial of low doses of propranolol, nortriptyline, and the combination of propranolol and nortriptyline for the preventive treatment of migraine.
    Arquivos de neuro-psiquiatria, 2009, Volume: 67, Issue:4

    Topics: Adrenergic beta-Antagonists; Adult; Antidepressive Agents, Tricyclic; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Migraine Disorders; Nortriptyline; Propranolol; Treatment Outcome

2009

Other Studies

43 other study(ies) available for propranolol and nortriptyline

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
High-throughput screening of drug-brain tissue binding and in silico prediction for assessment of central nervous system drug delivery.
    Journal of medicinal chemistry, 2007, Sep-20, Volume: 50, Issue:19

    Topics: Animals; Brain; Central Nervous System Agents; Dialysis; Hydrophobic and Hydrophilic Interactions; In Vitro Techniques; Mice; Models, Statistical; Protein Binding; Quantitative Structure-Activity Relationship; Rats

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2

    Topics: Absorption; Albumins; Animals; Brain; Brain Chemistry; Cell Membrane; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; In Vitro Techniques; Lipids; Male; Microdialysis; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tissue Distribution

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Which metabolites circulate?
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:5

    Topics: Humans; Metabolic Clearance Rate; Pharmaceutical Preparations

2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
[The extrapyramidal symptoms in the combination of lithium long-term lithium therapy with nortriptyline. A case report on the formation of a pathogenesis hypothesis].
    Der Nervenarzt, 1976, Volume: 47, Issue:1

    Topics: Adult; Basal Ganglia Diseases; Bipolar Disorder; Chlorprothixene; Clopenthixol; Dibenzazepines; Drug Synergism; Drug Therapy, Combination; Female; Humans; Lithium; Long-Term Care; Nortriptyline; Parkinson Disease; Parkinson Disease, Secondary; Procyclidine; Propranolol; Synapses; Thioridazine

1976
Carotidynia.
    Neurology, 1977, Volume: 27, Issue:1

    Topics: Adult; Aged; Carotid Artery Diseases; Dose-Response Relationship, Drug; Ergonovine; Female; Headache; Humans; Jaw Diseases; Methysergide; Middle Aged; Migraine Disorders; Nortriptyline; Pain; Propranolol

1977
Influence of some antidepressant drugs on the circulatory system: II. Action of amitriptyline and nortriptyline on basic circulatory parameters.
    Archivum immunologiae et therapiae experimentalis, 1975, Volume: 23, Issue:6

    Topics: Amitriptyline; Animals; Atropine; Cats; Dihydroergotamine; Hemodynamics; In Vitro Techniques; Muscle, Smooth; Myocardial Contraction; Norepinephrine; Nortriptyline; Propranolol; Quaternary Ammonium Compounds; Rabbits; Respiration

1975
Studies on active transport of (E)-10-hydroxynortriptyline in the kidney and brain of rats: effects of propranolol and quinidine.
    Pharmacology & toxicology, 1991, Volume: 68, Issue:5

    Topics: Animals; Biological Transport, Active; Brain; Disease Models, Animal; Kidney; Male; Metabolic Clearance Rate; Nortriptyline; Propranolol; Quinidine; Rats; Rats, Inbred Strains

1991
Effects of chronic antidepressant treatment on alpha 1- and alpha 2-adrenoceptors in the rat anococcygeus muscle.
    Journal of neural transmission. General section, 1990, Volume: 82, Issue:3

    Topics: Animals; Antidepressive Agents; Cocaine; Desipramine; Electric Stimulation; Male; Mianserin; Muscle Contraction; Muscles; Nomifensine; Normetanephrine; Nortriptyline; Phenylephrine; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Xylazine

1990
Mean time and first-pass metabolism.
    European journal of clinical pharmacology, 1985, Volume: 29, Issue:1

    Topics: Humans; Models, Biological; Molsidomine; Nortriptyline; Pharmaceutical Preparations; Propranolol; Regression Analysis; Sydnones; Time Factors

1985
Bipolar affective symptoms associated with use of captopril and abrupt withdrawal of pargyline and propranolol.
    The American journal of psychiatry, 1985, Volume: 142, Issue:6

    Topics: Bipolar Disorder; Captopril; Drug Therapy, Combination; Female; Humans; Hypertension; Middle Aged; Nortriptyline; Pargyline; Proline; Propranolol; Substance Withdrawal Syndrome

1985
Potentiation of monoaminergic activity in peripheral ganglia by tricyclic antidepressants.
    European journal of pharmacology, 1972, Volume: 20, Issue:1

    Topics: Action Potentials; Animals; Antidepressive Agents; Cats; Desipramine; Dibenzocycloheptenes; Dopamine; Drug Synergism; Epinephrine; Ganglia; Norepinephrine; Nortriptyline; Propranolol; Serotonin; Synaptic Transmission; Time Factors

1972
Pharmacological studies on modaline sulphate (w 3207).
    The Journal of pharmacy and pharmacology, 1965, Volume: 17, Issue:11

    Topics: Antidepressive Agents; Desipramine; Dibenzylchlorethamine; Dihydroxyphenylalanine; Fever; Hydrazines; Isoproterenol; Monoamine Oxidase Inhibitors; Nortriptyline; Phentolamine; Proadifen; Propranolol; Reserpine; Sympatholytics; Tryptamines

1965
Effect of antidepressant and adrenergic blocking drugs on hyperthermia induced by reserpine.
    Archives internationales de pharmacodynamie et de therapie, 1967, Volume: 165, Issue:2

    Topics: Amitriptyline; Animals; Antidepressive Agents; Atropine; Body Temperature; Chlorisondamine; Chlorpromazine; Desipramine; Ethanolamines; Female; Fever; Hydrazines; Imipramine; Monoamine Oxidase Inhibitors; Norepinephrine; Nortriptyline; Phenoxybenzamine; Phentolamine; Propranolol; Rats; Reserpine; Sympatholytics; Tetrabenazine

1967
Cardiovascular effects of poisoning with tricyclic antidepressants.
    Acta medica Scandinavica, 1974, Volume: 195, Issue:6

    Topics: Adult; Amitriptyline; Blood; Blood Pressure; Body Temperature; Carbon Dioxide; Cardiac Output; Coma; Depression, Chemical; Electrocardiography; Female; Heart Rate; Humans; Hydrogen-Ion Concentration; Male; Middle Aged; Nortriptyline; Oxygen; Oxygen Consumption; Partial Pressure; Positive-Pressure Respiration; Propranolol; Stimulation, Chemical; Suicide; Time Factors

1974
Physiological and pharmacokinetic complexities in bioavailability testing.
    Pharmacology, 1972, Volume: 8, Issue:1

    Topics: Administration, Oral; Animals; Autoradiography; Biopharmaceutics; Carbon Isotopes; Cats; Diazepam; Dosage Forms; Half-Life; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Intestines; Kinetics; Male; Mice; Nortriptyline; Propranolol; Quinidine; Radiography; Solubility; Stomach; Tetracycline; Time Factors; Water

1972
Relationship between substances strengthening of the thrombocyte cell membrane on the aggregation of thrombocytes and on the uptake and release of serotonin.
    Acta Universitatis Carolinae. Medica. Monographia, 1972, Volume: 53

    Topics: Adenosine Diphosphate; Amitriptyline; Benzothiepins; Blood Platelets; Cell Membrane; Cell Membrane Permeability; Chlorpromazine; Colorimetry; Desipramine; Epinephrine; Humans; Imipramine; In Vitro Techniques; Nortriptyline; Phentolamine; Piperazines; Platelet Adhesiveness; Propranolol; Receptors, Adrenergic; Serotonin; Serotonin Antagonists; Spectrometry, Fluorescence; Tranquilizing Agents

1972
The importance of stable isotope labelled drugs in clinical pharmacology: with illustrations from studies on the disposition of propranolol and nortriptyline in man.
    Southern medical journal, 1974, Volume: 67, Issue:8

    Topics: Animals; Biotransformation; Chromatography, Gas; Computers; Humans; Isotopes; Mass Spectrometry; Nortriptyline; Pharmaceutical Preparations; Propranolol; Research Design

1974
Metabolism of propranolol by rat liver microsomes and its inhibition by phenothiazine and tricyclic antidepressant drugs.
    Biochemical pharmacology, 1971, Volume: 20, Issue:7

    Topics: Amitriptyline; Animals; Antidepressive Agents; Chlorpromazine; Desipramine; Imipramine; Kinetics; Liver; Male; Metabolism; Microsomes, Liver; NAD; NADP; Nitrogen; Nortriptyline; Perphenazine; Phenothiazines; Prochlorperazine; Promazine; Promethazine; Propranolol; Rats; Subcellular Fractions; Trifluoperazine; Triflupromazine

1971
Marked sinus tachycardia resulting from the synergistic effects of marijuana and nortriptyline.
    The American journal of psychiatry, 1983, Volume: 140, Issue:5

    Topics: Adult; Dronabinol; Drug Synergism; Female; Humans; Marijuana Abuse; Nortriptyline; Propranolol; Tachycardia

1983
Propranolol, depression, and nortriptyline interaction.
    The American journal of psychiatry, 1984, Volume: 141, Issue:8

    Topics: Depressive Disorder; Drug Interactions; Humans; Nortriptyline; Propranolol

1984
Novel solid-phase extraction strategy for the isolation of basic drugs from whole blood. Preliminary study using commercially available extraction cartridges.
    Journal of chromatography. B, Biomedical applications, 1995, Jul-21, Volume: 669, Issue:2

    Topics: Adsorption; Animals; Blood Chemical Analysis; Cation Exchange Resins; Chromatography; Gas Chromatography-Mass Spectrometry; Imipramine; Nortriptyline; Pharmaceutical Preparations; Propranolol; Quinine; Sheep; Solubility

1995
Sudden chest pain with sertraline.
    Lancet (London, England), 1994, Apr-30, Volume: 343, Issue:8905

    Topics: 1-Naphthylamine; Antidepressive Agents; Aspirin; Chest Pain; Coronary Disease; Depression; Humans; Male; Middle Aged; Nortriptyline; Propranolol; Sertraline

1994
Alpha-adrenergic receptors mediate imipramine/alarm substance-induced reaction in rats.
    Physiology & behavior, 1994, Volume: 56, Issue:2

    Topics: Animals; Arousal; Brain; Citalopram; Clonidine; Dose-Response Relationship, Drug; Imipramine; Male; Norepinephrine; Nortriptyline; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Receptors, Adrenergic, alpha-2; Receptors, GABA; Reserpine; Serotonin; Yohimbine

1994
Akathisia in association with nortriptyline therapy.
    American family physician, 1993, Nov-01, Volume: 48, Issue:6

    Topics: Adult; Aged; Akathisia, Drug-Induced; Female; Humans; Male; Nortriptyline; Propranolol

1993
Pharmacophore modeling for hERG channel facilitation.
    Biochemical and biophysical research communications, 2012, Feb-03, Volume: 418, Issue:1

    Topics: Animals; Atenolol; Chlorpheniramine; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Fluoxetine; Haloperidol; Humans; Hydrophobic and Hydrophilic Interactions; Imipramine; Metoprolol; Nortriptyline; Potassium Channel Blockers; Promethazine; Propranolol; Quantitative Structure-Activity Relationship; Sotalol; Terfenadine; Verapamil; Xenopus laevis

2012
α₂- and β-adrenoceptors involvement in nortriptyline modulation of auditory sustained attention and impulsivity.
    Psychopharmacology, 2012, Volume: 222, Issue:2

    Topics: Acoustic Stimulation; Adrenergic Uptake Inhibitors; Animals; Attention; Dose-Response Relationship, Drug; Impulsive Behavior; Male; Norepinephrine; Nortriptyline; Prazosin; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Adrenergic, beta; Time Factors; Yohimbine

2012
Pharmacotherapy failure and progression to botulinum toxin injection in vestibular migraine.
    The Journal of laryngology and otology, 2020, Volume: 134, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Botulinum Toxins; Dizziness; Female; Humans; Injections; Male; Middle Aged; Migraine Disorders; Nortriptyline; Propranolol; Retrospective Studies; Risk Factors; Topiramate; Treatment Failure; Verapamil; Young Adult

2020